Podcasts about sleep wake

In today's episode, we're joined by Phil Learney, founder of Advanced Coaching Academy and co-founder of HMN24, a supplement range to optimise sleep-wake cycles. Phil discusses his experiences with caffeine and other stimulants and what inspired him to find a solution to better his health and wellness. We delve into the science behind sleep-wake cycles as well as the culture surrounding caffeine and stimulants and the impact they can have on your body. After 26 years in the fitness industry, Phil explains his journey as a coach and advice on maintaining high levels of service for your clients. Furthermore, we look at how fitness business owners can create added value to their fitness business. Finally, we discuss the direction of the fitness business and the surge in recovery and supplements. Key Highlights: How to optimise yourself and your daily activity.   His journey into getting into the wellness industry and history with stimulants.   The culture surrounding caffeine and stimulants on an everyday basis.   Optimising your focus levels and how that will affect the quality of coaching with each client.   Phil's experience within the coaching industry and how he expanded his number of clients and increased pricing.   How to upgrade your levels of coaching service.   Deep dive into the science behind HMN24 products.   Phil's routine with training, sleep and nutrition.   Lessons learned and mistakes Phil has made within his fitness business.   Future of the fitness industry and the growth in wellness and recovery. To find out how Fitness Marketing Agency can help your Fitness Business, book a demo call using the link below: https://fitnessmarketingagency.com/discoverycall?sl=podcastshownotes Connect with Fitness Marketing Agency on Instagram: https://www.instagram.com/fitnessmarketingagency/ Find out more about HMN24: https://www.instagram.com/hmn24_/ https://hmn24.com/ Connect with Phil: https://www.instagram.com/theptcoach/

Moderator: Rolf Fronczek (Leiden, The Netherlands)Guest: Marina Tüzün (Bern, Switzerland)Rolf Fronczek and Marina Tüzün discuss the Burden of Sleep Disorders Project, targeting daytime sleepiness and insomnia across Europe. They emphasize primary care collaboration for effective management, including patient perspectives and long-term follow-ups. Dr. Tüzün's personal interest in sleep research drives her involvement, inviting listeners to stay updated on the project's progress.

In this episode, I am joined by Dr Jade Murray. Dr. Jade M. Murray completed a PhD programme at the Monash University Sleep and Circadian Medicine Laboratory in 2018. Dr Murray's broad research interests include studying the effects of circadian misalignment on overall health in healthy and sleep-disordered populations and developing simplified methods for determining the timing of the circadian phase. An important innovation in her work has been tracking light-dark exposure data over time to build predictive models of circadian timing for the development of personalised delivery systems for sleep-wake interventions. In this episode, we discuss Jade's recent paper "Murray JM, Magee M, Giliberto ES, Booker LA, Tucker AJ, Galaska B, Sibenaller SM, Baer SA, Postnova S, Sondag TAC, Phillips AJK, Sletten TL, Howard ME, Rajaratnam SMW. Mobile app for personalized sleep-wake management for shift workers: A user testing trial. Digit Health. 2023 Mar 29" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064476/ Connect w Jade on LinkedIn https://www.linkedin.com/in/jade-murray-652442163/  ResearchGate https://www.researchgate.net/profile/Jade-Murray-2  Contact me at iandunican@sleep4performance.com.au or www.sleep4performance.com.au  and check out the YouTube channel. Check out our sponsor, LMNT. Click on the link to order and get a free LMNT Sample Pack when you order through the custom link below. Key details: The LMNT Sample Pack includes 1 packet of every flavour. This is the perfect offer for anyone interested in trying all our flavours or wanting to introduce a friend to LMNT. This offer is exclusively available through VIP LMNT Partners – you won't find this offer publicly available. This offer is available for new and returning customers. They offer refunds on all orders with no questions – you don't even have to send it back! http://drinklmnt.com/sleep4performance

This week I discuss some simple habits to help optimize your circadian rhythm in order to have the best night's rest possible! As you age, your circadian rhythm may change, and you may experience more sleep problems. For example, you may have trouble falling asleep or staying asleep. This is because the natural levels and timing of melatonin production, a hormone that regulates sleep, alters. Additionally, older adults may produce less melatonin. This can affect your ability to sleep well at night, which in turn can reduce concentration and productivity during the day.Here are a few tips to help optimize your sleep - wake cycles:- Go to bed and wake up at the same time everyday (even weekends)- Get natural light early in the day and avoid blue light later in the evening (check out bluelight blocking glasses)- Finish eating at least 2-3 hours before bedtimeand lastly weekly exercise can help relieve stress and improve the quality of your sleep!If you love the Get Lean Eat Clean Podcast, we'd love for you to subscribe, rate, and give a review on Apple Podcasts and Spotify! Until next time!Links:Watch Get Lean Eat Clean podcast video episodes on YouTube!How to Take Simple Steps to Reclaim the Body, Energy, and Strength You Had 10-15 Years Ago Using My Stepladder System:https://www.stepladdersystem.com/LMNT: A tasty electrolyte drink mix that is formulated to help anyone with their electrolyte needs and is perfectly suited to folks fasting or following low-carb, whole food diets. Free gift with purchase:DrinkLMNT.com/getleaneatcleanUpgraded Formulas hair mineral test (Coupon Code: GETLEAN10) :https://www.upgradedformulas.com/pages/kit?rfsn=6677062.f87541&utm_source=refersion&utm_medium=affiliate&utm_campaign=6677062.f87541X3 Bar: Variable Resistance Technology allows for a full body workout in only 10 minutes! Use discount code "Save50" for $50 off your purchase! https://www.anrdoezrs.net/click-100286468-13650338| Listen to the Get Lean Eat Clean Podcast |►Apple Podcasts | https://podcasts.apple.com/us/podcast/get-lean-eat-clean/id1540391210►Spotify | https://open.spotify.com/show/0QmJzYZsdV6tUNbDxaPJjS| Connect with Brian |►Website | https://www.briangryn.com►Instagram | https://www.instagram.com/bdgryn►Facebook | https://www.facebook.com/getleanandeatclean►Twitter | https://twitter.com/grynnerwinner

Did you know that 30% of adults report signs of insomnia and only 10% actually meet the DSM-5-TR criteria?Insomnia is a common sleep disorder that affects millions of people worldwide. If you're struggling to get a good night's sleep, it's important to understand what insomnia is and how it can impact your health and well-being.In this video, we'll talk about these criteria, the causes and risk factors, and practical strategies for managing and treating this sleep disorder. From lifestyle changes to medication, many options are available to help you get the restful sleep you deserve. 

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.07.536063v1?rss=1 Authors: Harvey, B. J., Olah, V. J., Aiani, L. M., Rosenberg, L. I., Pedersen, N. P. Abstract: Independent automated scoring of sleep-wake and seizures have recently been achieved; however, the combined scoring of both states has yet to be reported. Mouse models of epilepsy typically demonstrate an abnormal electroencephalographic (EEG) background with significant variability between mice, making combined scoring a more difficult classification problem for manual and automated scoring. Given the extensive EEG variability between epileptic mice, large group sizes are needed for most studies. As large datasets are unwieldy and impractical to score manually, automatic seizure and sleep-wake classification are warranted. To this end, we developed an accurate automated classifier of sleep-wake states, seizures, and the post-ictal state. Our benchmark was a classification accuracy at or above the 93% level of human inter-rater agreement. Given the failure of parametric scoring in the setting of altered baseline EEGs, we adopted a machine-learning approach. We created several multi-layer neural network architectures that were trained on human-scored training data from an extensive repository of continuous recordings of electrocorticogram (ECoG), left and right hippocampal local field potential (HPC-L and HPC-R), and electromyogram (EMG) in the murine intra-amygdala kainic acid model of medial temporal lobe epilepsy. We then compared different network models, finding a bidirectional long short-term memory (BiLSTM) design to show the best performance with validation and test portions of the dataset. The SWISC (sleep-wake and the ictal state classifier) achieved greater than 93% scoring accuracy in all categories for epileptic and non-epileptic mice. Classification performance was principally dependent on hippocampal signals and performed well without EMG. Additionally, performance is within desirable limits for recording montages featuring only ECoG channels, expanding its potential scope. This accurate classifier will allow for rapid combined sleep-wake and seizure scoring in mouse models of epilepsy and other neurologic diseases with varying EEG abnormalities, thereby facilitating rigorous experiments with larger numbers of mice. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This episode Ali walks us through some books that were found in the 10.0.7 datamining, and she discusses with Gin what that may all mean for the future of the expansion!  Support us on Patreon! https://www.patreon.com/livelaughlore  Follow up on Twitter! Show: @live_laugh_lore Gin: @GinsJoint Ali: @AliandrasK

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.03.527083v1?rss=1 Authors: Gu, X., Zhang, L., Zhao, Z., Fang, H., Zhao, T., Ju, S., Chen, X., Gao, W., Qian, X., Wang, X., Zhang, J., Cheng, H. Abstract: Microglia surveillance manifests itself as dynamic changes in cell morphology and functional remodeling in response to fluctuations in the neural environment. Whether and how microglia surveillance is coupled to brain state switches during natural sleep-wake cycles, as well as under sleep deprivation, remain unclear. To address this question, we used miniature two-photon microscopy (mTPM) to acquire time-lapse high-resolution microglia images of the somatosensory cortex, along with EEG/EMG recordings and behavioral video, in freely-behaving mice. We uncovered fast and robust brain state-dependent changes in microglia surveillance, occurring in parallel with sleep dynamics and early-onset phagocytic microglial contraction during sleep deprivation stress. With the aid of the biosensor GRABNE2m, we also detected local norepinephrine fluctuation occurring in a sleep state-dependent manner. We showed that the locus coeruleus-norepinephrine system, which is crucial to sleep homeostasis, is required for both sleep state-dependent and stress-induced microglial responses and involves {beta}2-adrenergic receptor signaling. These results provide direct evidence that microglial surveillance is exquisitely tuned to signals and stressors that regulate sleep dynamics and homeostasis so as to adjust its varied roles to complement those of neurons in the brain. In vivo imaging with mTPM in freely behaving animals, as demonstrated here, opens a new avenue for future investigation of microglia dynamics and sleep biology in freely behaving animals. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Huberman Lab Podcast Notes Key Takeaways High-quality sleep is critical! Sleep is the foundation of mental health, cognitive health, and performanceViewing direct morning sunlight within 30-60 minutes of waking will help you fall asleep and stay asleep at night, and optimize cortisol & adenosine levelsLayer in multiple levers to be more alert: morning sunlight viewing, increasing body temperature, delaying caffeine, movement/exercise upon waking, light breakfastStack the deck to give your body predictable autonomic timing and properly set circadian rhythm to optimize sleep and wakefulness – even if you're tired, exercise a little (doesn't have to be intense) and eat a light breakfast, etc.Avoid overhead fluorescent light as much as possible between 10pm-4am – these lights will eliminate melatonin circulating in brain & body and will hinder ability to fall and stay asleep (instead, try soft lamps and dim screens as much as possible without straining eyes)Viewing afternoon sunlight from sunset can help offset some of the negative effects of light viewing in the evening (10 pm-4 am)Try to maintain a consistent sleep/wake schedule (+/- 1 hour) 7 days a week!When all else fails, try this sleep stack cocktail (buy single ingredient supplements so you can use what works, ditch what doesn't): magnesium threonate (145mg, 30-60 minutes before bed) + theanine (100-400mg, 30-60 minutes before bed) + apigenin (50mg, 30-60 minutes before bed)Sleep apnea can have very damaging effects on sleep and health – train nasal breathing with these methods: (1) use medical tape to tape mouth shut during sleep; (2) practice nasal breathing only during light exercise/cardio boutsRead the full notes @ podcastnotes.orgIn this episode, I describe a comprehensive toolkit consisting of behavioral and supplement-based tools that you can customize to enhance the quality, duration and impact of your sleep. This has an enormous positive impact on your overall health and daytime functioning, brain, hormones and immune system. I teach you how to effectively harness light (and darkness), temperature, food, exercise, caffeine, supplements, and digital devices in order to fall asleep faster, stay deeply asleep longer and overall, and achieve better quality sleep. I also describe how these tools can be modified to recover quickly from a poor night's sleep, jet lag or bouts of shift work. Given that sleep is the foundation of all mental health, physical health and performance, this episode should benefit everyone as it provides an essential toolkit of science-supported, low- to zero-cost strategies that can be tailored to optimize your sleep routine. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Eight Sleep: https://www.eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Tools to Optimize Sleep (00:03:02) Momentous Supplements (00:04:16) InsideTracker, Eight Sleep, LMNT (00:08:24) Factors to Control Circadian Rhythm & Sleep (00:15:10) Morning Tool: Morning Sunlight Viewing, Cortisol (00:20:44) Morning Sunlight: Circadian Rhythm, Artificial Lights, Cloudy Days (00:26:18) Evaluating Light in Environment, Compensating for Missed Morning Light (00:29:26) AG1 (Athletic Greens) (00:30:46) Morning Tools: Temperature & Deliberate Cold Exposure, Exercise (00:34:58) Timing Caffeine, “Afternoon Crash,” Exercise (00:40:08) Timing Eating, Alertness & Circadian Rhythm (00:45:20) 3 Daily Critical Periods (00:46:49) Afternoons: Naps, Deep Relaxation (NSDR, Self-Hypnosis), Exercise & Body Temperature, Caffeine (00:51:59) Afternoon Tools: Viewing Sunlight in Late Afternoon, Evening Light (00:56:45) Evening/Night Tools: Overhead Artificial Lights, Light Sensitivity (01:04:40) Evening Tools: Hot Bath/Sauna, Temperature & Sleeping Environment (01:09:40) Alcohol, THC & Reduced Sleep Quality; CBD, Anxiety & Falling Asleep (01:11:45) Sleep Supplements: Magnesium Threonate, Apigenin & Theanine (01:16:34) Melatonin Supplementation (Caution) (01:17:44) Additional Sleep Supplements: GABA, Glycine, Myo-Inositol & Anxiety (01:20:08) Falling Back Asleep: Reveri App, NSDR, Yoga Nidra (01:22:55) Staying Asleep: Eye Masks, Ear Plugs, Elevating Feet (01:24:58) Tool: Sleep Apnea & Nasal Breathing (01:28:20) Sleep Schedule Consistency, Weekends, Compensatory Sleep & Caffeine (01:31:14) Tools: Temperature Minimum & Jet Lag, Shift Work & Red Lights (01:37:38) Behavioral Tools for 3 Daily Critical Periods (01:39:26) Zero-Cost Support, YouTube Feedback, Huberman Lab Clips, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, I describe a comprehensive toolkit consisting of behavioral and supplement-based tools that you can customize to enhance the quality, duration and impact of your sleep. This has an enormous positive impact on your overall health and daytime functioning, brain, hormones and immune system. I teach you how to effectively harness light (and darkness), temperature, food, exercise, caffeine, supplements, and digital devices in order to fall asleep faster, stay deeply asleep longer and overall, and achieve better quality sleep. I also describe how these tools can be modified to recover quickly from a poor night's sleep, jet lag or bouts of shift work. Given that sleep is the foundation of all mental health, physical health and performance, this episode should benefit everyone as it provides an essential toolkit of science-supported, low- to zero-cost strategies that can be tailored to optimize your sleep routine. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Eight Sleep: https://www.eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Tools to Optimize Sleep (00:03:02) Momentous Supplements (00:04:16) InsideTracker, Eight Sleep, LMNT (00:08:24) Factors to Control Circadian Rhythm & Sleep (00:15:10) Morning Tool: Morning Sunlight Viewing, Cortisol (00:20:44) Morning Sunlight: Circadian Rhythm, Artificial Lights, Cloudy Days (00:26:18) Evaluating Light in Environment, Compensating for Missed Morning Light (00:29:26) AG1 (Athletic Greens) (00:30:46) Morning Tools: Temperature & Deliberate Cold Exposure, Exercise (00:34:58) Timing Caffeine, “Afternoon Crash,” Exercise (00:40:08) Timing Eating, Alertness & Circadian Rhythm (00:45:20) 3 Daily Critical Periods (00:46:49) Afternoons: Naps, Deep Relaxation (NSDR, Self-Hypnosis), Exercise & Body Temperature, Caffeine (00:51:59) Afternoon Tools: Viewing Sunlight in Late Afternoon, Evening Light (00:56:45) Evening/Night Tools: Overhead Artificial Lights, Light Sensitivity (01:04:40) Evening Tools: Hot Bath/Sauna, Temperature & Sleeping Environment (01:09:40) Alcohol, THC & Reduced Sleep Quality; CBD, Anxiety & Falling Asleep (01:11:45) Sleep Supplements: Magnesium Threonate, Apigenin & Theanine (01:16:34) Melatonin Supplementation (Caution) (01:17:44) Additional Sleep Supplements: GABA, Glycine, Myo-Inositol & Anxiety (01:20:08) Falling Back Asleep: Reveri App, NSDR, Yoga Nidra (01:22:55) Staying Asleep: Eye Masks, Ear Plugs, Elevating Feet (01:24:58) Tool: Sleep Apnea & Nasal Breathing (01:28:20) Sleep Schedule Consistency, Weekends, Compensatory Sleep & Caffeine (01:31:14) Tools: Temperature Minimum & Jet Lag, Shift Work & Red Lights (01:37:38) Behavioral Tools for 3 Daily Critical Periods (01:39:26) Zero-Cost Support, YouTube Feedback, Huberman Lab Clips, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

In this episode, I describe a comprehensive toolkit consisting of behavioral and supplement-based tools that you can customize to enhance the quality, duration and impact of your sleep. This has an enormous positive impact on your overall health and daytime functioning, brain, hormones and immune system. I teach you how to effectively harness light (and darkness), temperature, food, exercise, caffeine, supplements, and digital devices in order to fall asleep faster, stay deeply asleep longer and overall, and achieve better quality sleep. I also describe how these tools can be modified to recover quickly from a poor night's sleep, jet lag or bouts of shift work. Given that sleep is the foundation of all mental health, physical health and performance, this episode should benefit everyone as it provides an essential toolkit of science-supported, low- to zero-cost strategies that can be tailored to optimize your sleep routine. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Eight Sleep: https://www.eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Tools to Optimize Sleep (00:03:02) Momentous Supplements (00:04:16) InsideTracker, Eight Sleep, LMNT (00:08:24) Factors to Control Circadian Rhythm & Sleep (00:15:10) Morning Tool: Morning Sunlight Viewing, Cortisol (00:20:44) Morning Sunlight: Circadian Rhythm, Artificial Lights, Cloudy Days (00:26:18) Evaluating Light in Environment, Compensating for Missed Morning Light (00:29:26) AG1 (Athletic Greens) (00:30:46) Morning Tools: Temperature & Deliberate Cold Exposure, Exercise (00:34:58) Timing Caffeine, “Afternoon Crash,” Exercise (00:40:08) Timing Eating, Alertness & Circadian Rhythm (00:45:20) 3 Daily Critical Periods (00:46:49) Afternoons: Naps, Deep Relaxation (NSDR, Self-Hypnosis), Exercise & Body Temperature, Caffeine (00:51:59) Afternoon Tools: Viewing Sunlight in Late Afternoon, Evening Light (00:56:45) Evening/Night Tools: Overhead Artificial Lights, Light Sensitivity (01:04:40) Evening Tools: Hot Bath/Sauna, Temperature & Sleeping Environment (01:09:40) Alcohol, THC & Reduced Sleep Quality; CBD, Anxiety & Falling Asleep (01:11:45) Sleep Supplements: Magnesium Threonate, Apigenin & Theanine (01:16:34) Melatonin Supplementation (Caution) (01:17:44) Additional Sleep Supplements: GABA, Glycine, Myo-Inositol & Anxiety (01:20:08) Falling Back Asleep: Reveri App, NSDR, Yoga Nidra (01:22:55) Staying Asleep: Eye Masks, Ear Plugs, Elevating Feet (01:24:58) Tool: Sleep Apnea & Nasal Breathing (01:28:20) Sleep Schedule Consistency, Weekends, Compensatory Sleep & Caffeine (01:31:14) Tools: Temperature Minimum & Jet Lag, Shift Work & Red Lights (01:37:38) Behavioral Tools for 3 Daily Critical Periods (01:39:26) Zero-Cost Support, YouTube Feedback, Huberman Lab Clips, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

Napping... Isn't it glorious?!  Not that long ago we interviewed a senior lecturer at the Sleep/Wake research centre who said napping - and filling up your 7 to 9 hour “sleep quota” - is a good thing. But now new research published in Hypertension, an American Heart Association journal, has revealed people who regularly nap have a greater chance of developing high blood pressure and having strokes.  Michael Grandner, the director of the Behavioural Sleep Medicine Clinic from Tucson in Arizona, joins us with findings.See omnystudio.com/listener for privacy information.

Moderators: Prof. Thomas Berger (Vienna, Austria) and Dr. Ambra Stefani (Innsbruck, Austria)Guest: Prof. Claudio Bassetti (Bern, Switzerland)The final episode focusing on Sleep-Wake disorders brings together the monthly moderators, Prof. Berger and Dr. Stefani, with Prof. Claudio Bassetti to discuss controversies and other hot topics in narcolepsy.

Moderators: Prof. Thomas Berger (Vienna, Austria) and Dr. Ambra Stefani (Innsbruck, Austria)Guest: Dr. Evelina Pajediene (Vilnius, Lithuania)Prof. Berger and Dr. Stefani speak with sleep specialist Dr. Evelina Pajediene about the basics of sleep complaints and sleep-wake disorders, as well as what students and new residents will need to know about sleep-wake disorders.

Back to the basics. Everything impacts something else. At your own preferred pace you can start to feel more on track. Identify the areas of the most struggle, for me I have them listed as sleep, wake, energy and mood. These are my major focuses lately. And I try and ground with spiritual practices and nourishment of deep breathing, food, nature, music, art/craft. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

As professional working moms who are busy, we all sacrifice sleep in order to get more things done. Many of us battle with how to get quality sleep. Host, Dr. Rupa Wong, physician and working mom to 3 kids is joined by sleep specialist Dr. Shelby Harris in this week's episode. They discuss: What consitutes good sleep health and why it matters Indicators that you aren't getting enough sleep How sleep and poor sleep habits affect women Methods for treating sleep problems Things you can do each day to optimize the sleep you are getting Getting rid of the stigma for seeking help for sleep Dr. Shelby Harris is a clinical psychologist in private practice in NYC and is board certified in behavioral sleep medicine. She treats a wide variety of sleep, anxiety and depression issues using evidence-based, non-medication treatment. Before going Tinto private practice, she was the longstanding director of the Behavioral Sleep medicine Program at the Sleep-Wake disorders center at montefiore medical center. Dr. Harris has been an invited columnist for the New York Times and is frequently quoted in the media including The New Yorker and Washington Post, as well as appearing on the Today show, good morning America and CBS Mornings. Dr. Harris is on: Instagram: @SleepDocShelby www.drshelbyharris.com Get her book: "The Women's Guide to Overcoming Insomnia: Get a Good Night's Sleep Without Relying on Medication" 2 sleep apps discussed in the episode: SleepiO CBTiO Coach   Let's Connect! Topics for upcoming episodes? Email us at hello@itsgoodtoseeyou.com Instagram: @drrupawong Youtube: Doctor Mom Vlogs Tiktok: @drrupawong            

https://youtu.be/lVgfPnFz1WY This weeks' Blog is all about siblings and when they're room sharing and the effect that that can have on your little one's sleep including the all important; how you can make this work harmoniously and have siblings that share a room and sleep as well. The first thing I'm going to get you to ask yourself is why, why are your siblings going to room share first of all? Is it because it sounds lovely? It might just be that idea of, I want them to share a room. I would love for them to be together. And if we can make that work, brilliant. But you've got to ask yourself whether it's a nice fantasy idea or whether it's necessary. In some cases, it's going to be necessary. It's going to be a case of there are not enough bedrooms and the siblings have to share. And that's fine. But if you're battling with trying to get two siblings to sleep soundly and share a room, just ask yourself, is it worth it right now? And would it be better to actually work on improving their individual sleep in separate rooms until they're sleeping a little bit better and then bring them together to room share. II think it's really important to ask yourself a question and just think that through first before we delve into actually conquering sibling room sharing. In the longer term siblings will become quite resilient to each other especially when it comes to noises and sounds, things that might wake them up. Try to bear in mind that what might disturb them in the early days or initially when room sharing, they will get used to it and once they're in a deep sleep, they're not going to be disturbed by much at all. It's only really during light sleep that things, outside noises and things like that can actually wake us and rouse us from sleep. So they will become more used to each other. That will generally happen with time,but there may be a period of going through the pain barrier to get there, at which point until they are used to the noises of their siblings and the room they will wake up a little bit. This is another great time if it's an option to have them in the same room or separate that you can ask yourself, is it worth that? Is it worth paying the price? Is it worth going through that to get to the outcome? Because ultimately, at some point, if you want them to room share, you're probably going to have to go through that. Is it costing them precious sleep? Are you pushing them to do this at the cost of having an exhausted child, exhausted family and/or being miserable? Again, if it's essential and your children as siblings have to share a room and there's no other way around it, then let's make that work. So what can you do? Well, one of the most important things you can do, and this doesn't really matter, whether we're talking about a young baby or an older child, is to set up some really clear rules and boundaries. When I say that with babies, of course, they don't necessarily understand the rules or boundaries that you are implementing, but by setting the scene for those, and by having a consistent response to things, they will soon learn. For example, when lights are out and it's dark, shh, there's no talking. There's no voice. It's just whispers. You can begin to teach them that from baby stage by doing it, by making sure that when lights are out, nobody talks out loud, everything is just a whisper. It becomes nighttime mode and calm, and you can signal this simply by having the lights off. As they then get older from around 20 months, having a sleep wake clock in the room can really, really help. Sleep Wake clocks show when it's daytime and when it's nighttime. And when it's nighttime, we all can comply with nighttime mode. And when it's daytime, and time to be awake, it's a good idea to use exaggerated animation in our body language, our voices and our expressions just to really differentiate the two and show a big, clear, significant difference between daytime and nighttim...

Where to follow us and subscribe: www.crashdummiespodcast.com Join Our Patreon For Exclusive Content: https://www.patreon.com/ 0:00 - Intro 1:30 - Sallie Mae is on Instagram 4:27 - Parmesan Debate 9:15 - Mike's PSA 11:33 - Talking Dogs 13:31 - Haircuts (Then v Now) 19:10 - Spotify Wrap Up 24:33 - Merch Update 25:25 - Would you rather (Surviving 15 minutes) 30:34 - DM from Mohamed 36:46 - Fake Vaccination Card 39:17 - Celebrities Addressing Rumors 43:40 - What would you do? (Tik Tok) 45:10 - Would you rather ( Minor Super Power) 50:12 - Mikes Story/ How do you wake up? 52:21 - How do you get into your car? 54:44 - GPS talking ish 55:30 - Squid Games 2.0 59:39 - Kevin Hart & The Rock 1:04:29 - Would you rather (Sleep/Wake 20 hours) 1:07:11 - Price going up? 1:11:44 - Santa Clause is Real 1:17:05 - Nike 1:17:43 - YK Osiris 1:24:30 - Would you rather? ( Take back/ Hear everything) 1:28:00 - Outro --- Send in a voice message: https://anchor.fm/crash-dummies/message Support this podcast: https://anchor.fm/crash-dummies/support

Welcome to the Sleep/Wake cycle, where nightmares defy waking.Credits:Written by: Mark AnzaloneVoiced by: Mark Anzalone and Steven AnzaloneMusic by: Hampus Naeselius and Steven AnzaloneArtwork by: Guilluame DucosMastering by: Steven Anzalone See acast.com/privacy for privacy and opt-out information.

Kia ora Mosen At Largers. Here's what's on when. Remember, you can skip between these segments if you have a podcast client that supports chapters.   Introduction,0:00.000 Amazon Echo gets a new voice,1:16.053 The ACB convention,6:01.416 Sky New Zealand's Olympics app has accessibility issues,10:47.996 More feedback on OrCam MyEye,12:41.472 iOS 14.7 is out,19:05.096 The social model of disability is so last century!,22:57.324 Calling ableism out might upset the nondisabled,35:07.603 Feedback on the Pneuma Solutions interview,42:52.294 Edd Thomas talks about the Optophone,48:11.986 You can read the Optophone article here The Bonnie Bulletin in scary times,1:29:03.119 The Bonnie Bulletin in sad times,1:31:52.215 Unboxing the Apple MagSafe battery,1:34:21.835 Bonnie comments on getting on the job ladder,1:42:00.398 YouTube not working with Safari on iOS,1:45:17.189 Looking for hints on staying in step with a white cane,1:47:18.465 Coping with Non-24 Sleep/Wake disorder,1:49:39.736 Legacy Android gestures aren't so bad once explained properly,1:52:29.321 Why doesn't the keyboard shortcut list work with the Apple Wireless Keyboard on my iPhone?,1:55:27.000 How does the Touchbar work with VoiceOver on a Mac?,1:56:38.532 Closing and contact info,1:59:16.338   Share your thoughts on these topics or any others. Drop me an email in writing or with an audio attachment, Jonathan at MushroomFm.com, or phone the listener line in the United States, +1864-60Mosen, that's +18646066736. Keep up with Mosen At Large between episodes. Follow MosenAtLarge on Twitter where you'll get audio extras, links to interesting news stories, sneak peeks about what's coming up and more. If you'd like to subscribe to our announcements only email list, please send email to media-subscribe@mosen.org And if you like the show, we'd love a positive review and for you to spread the word. Thank you.

Louis The Child drops their brand new song “Sleep // Wake” plus a bunch of amazing music from the likes of Disclosure, SIDEPIECE, Brockhampton, Goth Babe, Lou Phelps and many more on a brand new #PlaygroundRadio! 01. Doja Cat - Streets (Disclosure Remix) [WEEKEND TRACK] 02. Goth Babe - I Wanna Help Your Mind 03. SIDEPIECE - Together 04. Nicky Romero - You Used To 05. Daft Punk - Harder, Better, Faster, Stronger 06. Steve Aoki & KREAM - LIES (VIP Mix) 07. Jessie Ware - Running (Disclosure VIP 2021 Remix) 08. Sia - The Girl You Lost To Cocaine (Sander van Doorn Remix) 09. Drake - What’s Next 10. Lou Phelps - PARTY IN LA 11. Nate Dae - Soul 12. glaive, ericdoa - cloak n dagger 13. Joyce Wrice - Kaytra’s Interlude (feat KAYTRANADA) 14. Justin Bieber - Peaches 15. Nate Das - Good Morning 16. D-Nice - No Plans For Love (with Ne-Yo & Kent Jones) 17. Louis The Child - Sleep // Wake 18. Brockhampton - Buzzcut (feat Danny Brown) [PLAYGROUND PICK]

Episode 57 - Work. Sleep. Wake. Cry. by Rice N Beans

Besser einschlafen und entspannter Aufwachen. In dieser Ausgabe des Gadget-Talk Podcast bringen wir euch das Philips Connected Sleep & Wake-Up Light vor, das euch App-gebunden beim Einschlafen und Aufstehen unterstützt. Wir gehen auf die Funktionen ein und geben euch ein Fazit zum Alltagsgadget. Wir freuen uns über eure Fragen, Kommentare und Kritik. Gerne erreicht ihr uns auch via Mail an: talk@gadget-rausch.de --- Send in a voice message: https://anchor.fm/gadget-talk/message

Do you sometimes struggle to fall asleep, wake up during the night and/or don't feel completely rested & energized the next day? Sleep is so important for our health and we really need to honour our body enough to give it the rest it deserves. I'm going to talk all about tips to get better sleep that will help you feel better the next day. I'm sending you much love and hope that you're doing well

Are you waking up feeling refreshed, energized and ready to go in the mornings? If you answered no, it might be from not getting enough good quality sleep! Sleep is one of the most underrated tools in the health and wellness world! Everyone wants to add in supplements, do more workouts, meditations, eat cleaner, etc. but it all comes back to sleep. With a strong foundation of consistent sleep, you won't have to do more of anything to feel like the best version of yourself! In today's episode, I'll dive deep into the importance of sleep and how to cultivate an environment that promotes deep, restorative sleep! In this episode you'll learn how to: - Invest in a great mattress - Understand the importance of clean sheets - Create a strong evening routine to support deep sleep - Understand the power of a consistent sleep schedule Resources mentioned in this episode: Invest in a Tuft & Needle mattress here: https://www.tuftandneedle.com/ Purchase MindBodyGreen Magnesium+ here: https://shareasale.com/r.cfm?b=1535186&u=2544468&m=96296&urllink=&afftrack= Let's connect on Social: @TheAliMcGPodcast @alimcg_ --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

We introduce some English expressions about being sleepy, sleeping, and waking up.11/7, 11/8, Nagoya Free Bird English Workshop!Twitter!  Instagram!  Please follow and send us questions or topics that you would like to hear us talk about.Transcripts!  You can read and listen at the same time for our first three episodes.Free Bird EnglishBen's MusicAbe's YouTubeGoGoエイブ会話Podcast (Apple)GoGo ProjectEmail: 55freebirdnow@gmail.com 

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.21.306456v1?rss=1 Authors: Bahari, F., Billard, M. W., Kimbugwe, J., Curay, C., Watson, G. D. R., Alloway, K. D., Gluckman, B. J. Abstract: Sleep-wake regulation is thought to be governed by interactions among several nuclei in midbrain, pons, and hypothalamic regions. Determination of the causal role of these nuclei in state transitions requires simultaneous measurements from the nuclei with sufficient spatial and temporal resolution. We obtained long-term experimental single- and multi-unit measurements simultaneously from multiple nuclei of the putative hypothalamic and brainstem sleep-wake regulatory network in freely behaving rats. Cortical and hippocampal activity, along with head acceleration were also acquired to assess behavioral state. We found that although the average activity of cell groups during states matches the patterns presented previously in brief recordings of individual nuclei in head-fixed animals, the firing rates with respect to cortical and behavioral signs of state transitions differ in critical ways. Our findings pose fundamental questions about the neural mechanisms that maintain specific states and the neural interactions that lead to the emergence of new states. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.12.246405v1?rss=1 Authors: Sela, Y., Hoekstra, M. M. B., Franken, P. Abstract: While brain temperature is of neurobiological and clinical importance, it is still unclear which factors contribute to its daily dynamics and to what degree. We recorded cortical temperature in mice alongside sleep-wake state during 4 days including a 6h sleep deprivation, and developed a mathematical tool to simulate temperature based on the sleep-wake sequence. The model estimated temperature with remarkable precision accounting for 91% of its variance based on three main factors with the sleep-wake sequence accounting for most of the variance (74%) and time-of-day (circadian) the least (9%). As third factor, prior wake prevalence, was discovered to up-regulate temperature, explaining 43% of the variance. With similar accuracy the model predicted cortical temperature in a second, independent cohort using the parameters optimized for the first. Our model corroborates the profound influence of sleep-wake state on brain temperature, and can help differentiate thermoregulatory from sleep-wake driven effects in experiments affecting both. Copy rights belong to original authors. Visit the link for more info

A leading sleep research centre is facing changes that could undermine its worldwide status. Massey University wants to absorb the Sleep Wake centre into another department due to a shortfall in funding. It says this will make no difference to the research, but others fear it will possibly curtail a pioneering attempt to combat fatigue in public hospitals. Phil Pennington reports.

Sleep on it. If it keeps you awake, deal with it. If not, you good. Wake up with a Spark of life. Listen and follow #DryerBuzz powered by http://DryerBuzz.com

In this episode of CUBIST, Don and Amanda discuss the article, “The Prevalence and Stability of Sleep-Wake Disturbance and Fatigue Throughout the First Year After Traumatic Brain Injury” published in the Journal of Neurotrauma in May of 2020. Article Citation: Saksvik, S. B., Karaliute, M., Kallestad, H., Follestad, T., Asarnow, R., Vik, A., Håberg, A. K., Skandsen, T., & Olsen, A. (2020). The Prevalence and Stability of Sleep-Wake Disturbance and Fatigue throughout the First Year after Mild Traumatic Brain Injury. Journal of Neurotrauma, 10.1089/neu.2019.6898. Advance online publication. https://doi.org/10.1089/neu.2019.6898 Article LINK: https://pubmed.ncbi.nlm.nih.gov/32460623/ DVBIC’s Management of Sleep Disturbances Following Concussion/Mild TBI Clinical Suite: https://dvbic.dcoe.mil/material/management-sleep-disturbances-following-concussionmild-tbi-clinical-suite CUBIST is a podcast for health care providers produced by the Defense and Veterans Brain Injury Center. We discuss the latest research on traumatic brain injury (TBI) most relevant to patient care. For more about TBI, including clinical tools, go to dvbic.dcoe.mil or email us at dha.DVBICinfo@mail.mil The views, opinions and/or findings contained in this podcast are those of the host and subject matter experts. They should not be construed as an official Department of Defense position, policy or decision unless so designated by other official documentation. Our theme song is “Upbeat-Corporate’ by WhiteCat available and was used according to Creative Commons Attribution-Noncommercial 4.0 licensing

In this episode of CUBIST, Don and Amanda discuss the article, “The Prevalence and Stability of Sleep-Wake Disturbance and Fatigue Throughout the First Year After Traumatic Brain Injury” published in the Journal of Neurotrauma in May of 2020. Article Citation: Saksvik, S. B., Karaliute, M., Kallestad, H., Follestad, T., Asarnow, R., Vik, A., Håberg, A. K., Skandsen, T., & Olsen, A. (2020). The Prevalence and Stability of Sleep-Wake Disturbance and Fatigue throughout the First Year after Mild Traumatic Brain Injury. Journal of Neurotrauma, 10.1089/neu.2019.6898. Advance online publication. doi.org/10.1089/neu.2019.6898 Article LINK: pubmed.ncbi.nlm.nih.gov/32460623/ DVBIC’s Management of Sleep Disturbances Following Concussion/Mild TBI Clinical Suite: dvbic.dcoe.mil/material/manageme…bi-clinical-suite CUBIST is a podcast for health care providers produced by the Defense and Veterans Brain Injury Center. We discuss the latest research on traumatic brain injury (TBI) most relevant to patient care. For more about TBI, including clinical tools, go to dvbic.dcoe.mil or email us at dha.DVBICinfo@mail.mil The views, opinions and/or findings contained in this podcast are those of the host and subject matter experts. They should not be construed as an official Department of Defense position, policy or decision unless so designated by other official documentation. Our theme song is “Upbeat-Corporate’ by WhiteCat available and was used according to Creative Commons Attribution-Noncommercial 4.0 licensing

Insomnia is a highly prevalent condition that presents in primary care, but nearly three quarters of all patients do not tell their providers about their symptoms. Unfortunately, insomnia can have serious consequences for patients' daily activities, quality of life, and mental and physical health. Recent developments in the understanding of insomnia have led to the availability of new treatment options, but clinicians may not be aware of these developments. In this episode, Dr. Paul P. Doghramji will discuss the importance of recognizing the condition, examine evidence-based treatment of insomnia, and review the role of orexin in the balance of sleep and wakefulness.Faculty Paul P. Doghramji, MD, FAAFPFamily PhysicianCollegeville Family PracticeMedical Director of Health ServicesCollegeville, PAHostGregg Sherman, MDChief Medical Officer/Course DirectorNational Association for Continuing EducationPlantation, FLThis educational activity is supported by an independent medical educational grant from Eisai.This activity is not certified for CME/CE credit.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.16.137034v1?rss=1 Authors: Konduru, S. S., Wallace, E. P., Pfammatter, J. A., Rodrigues, P. V., Jones, M., Maganti, R. Abstract: Study objectives: Traumatic brain injury (TBI) results in sequelae that include post-traumatic epilepsy (PTE) and sleep-wake disturbances. Here we sought to determine whether sleep characteristics could predict development of PTE in a model of severe TBI. Methods: Following controlled cortical impact (CCI), sham injury (craniotomy only) or no craniotomy (NC), CD-1 mice were implanted with epidural electroencephalography (EEG) and nuchal electromyography (EMG) electrodes. Acute (1st week) and chronic (months 1, 2 and 3 after injury) 1-week long video-EEG/EMG recordings were examined for epileptiform activity. We analyzed sleep-wake patterns manually and extracted high amplitude interictal events from EEG using an automated method. Sleep spindles and EEG delta power were derived from non-rapid eye movement (NREM) sleep epochs. Brain CTs (computerized tomography) were performed to quantify the extent of brain lesions in cohorts of sham and CCI. Results: Posttraumatic seizures were seen with CCI, whereas interictal epileptiform activity as well as sleep-wake disruptions (shorter wake or NREM bout lengths, shorter duration or lower power for spindles, and increased NREM EEG delta power) were seen in CCI and sham groups. No sleep feature predicted PTE. Follow up brain CTs showed a small lesion in the sham injury group suggesting a milder form of TBI that may account for their interictal activity and sleep changes. Conclusions: In our model, interictal epileptiform activity and sleep disruptions resulted from CCI and sham and thus, sham injury was not an optimal negative control. Further work is necessary to determine the relationship between sleep-wake disturbances and PTE. Copy rights belong to original authors. Visit the link for more info

Non-24 Sleep/Wake Disorder

New Heights Educational Group, Inc., promotes literacy for children and adults by offering a range of educational support services. Such services include the following: assisting families in the selection of schools; organization of educational activities; and acquisition of materials.  We promote a healthy learning environment and various enrichment programs for families of preschool and school-age children, including children with special needs.

Does it feel like an endless cycle? It does, but it will stop. But, until then...we'll be sittin on the dock of the bay, Wasting time.... --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/fiftyish/message Support this podcast: https://anchor.fm/fiftyish/support

Lee and Stephen King fans Kim and Dallas share their reaction to Doctor Sleep.

Lee and Stephen King fans Kim and Dallas share their reaction to Doctor Sleep.

Bombay Bicycle Club - Eat, Sleep, Wake (Nothing But You) - a 2019 single on Mmm...Records.Support the show: https://www.kexp.org/donateSee omnystudio.com/listener for privacy information.

Join The White Noise Podcast in a discussion of the diagnosis and management of Delayed Sleep Wake Phase Disorder (DSWPD) with special guest Dr. Cathy Goldstein, an expert in circadian rhythm disorders in Ann Arbor, Michigan and Chair of the Artificial Intelligence in Sleep Medicine subcommittee of the American Academy of Sleep Medicine (AASM). www.thewhitenoisepodcast.com

Join The White Noise Podcast in a discussion of the diagnosis and management of Delayed Sleep Wake Phase Disorder (DSWPD) with special guest Dr. Cathy Goldstein, an expert in circadian rhythm disorders in Ann Arbor, Michigan and Chair of the Artificial Intelligence in Sleep Medicine subcommittee of the American Academy of Sleep Medicine (AASM). www.thewhitenoisepodcast.com

--- Support this podcast: https://anchor.fm/brad-richardson/support

In this week’s VIP, Nelson and James are joined by Jeff Thompson from Blind Abilities and Randy Rusnak from ACB Radio. They discuss the top stories from Apple’s Keynote Event and give you some Cool Picks and tips. Top Stories Accessibility Changes Coming On The iPhone X The new iPhone X has an edge-to-edge screen and no Home Button, but will be using the Sleep/Wake button on the upper right hand side instead for functions such as the triple click feature for accessibility users and initiating Siri commands. Although we have yet to get our hands on the device to test accessibility features for VoiceOver users, Sighted users can wake the iPhone X by tapping on the screen. Users can then access the home screen by swiping up from the bottom of the phone. Switching between apps also requires swiping up from the bottom of the displays. Additionally, users can switch between apps by swiping from the bottom left of the phone. Unlocking the phone is done with the company new Face ID technology. The phone will remain locked until the iPhone X is able to see the user and positively identify their face using the phone’s TrueDepth camera system. We reached out to Apple on how VoiceOver users will be accommodated on the iPhone x and this is what they told us: "The iPhone X has been designed with a number of accessibility features to support its use. An Overview Of the Apple Event Apple announced this fall’s additions to their hardware lineup. They unveiled the Series 3 Apple Watch, a 4K version of the Apple TV, the iPhone 8 and 8+, along with a special iPhone X addition. Cool Picks All-New Element 43-Inch 4K Ultra HD Smart LED TV - Fire TV Edition LG HBS-910 Tone Infinim Bluetooth Stereo Headset - Black Bank of America Mobile Banking Monster Blaster Boombox Wireless Speaker

In this week’s VIP, Nelson and James are joined by Jeff Thompson from Blind Abilities and Randy Rusnak from ACB Radio. They discuss the top stories from Apple’s Keynote Event and give you some Cool Picks and tips. Top Stories Accessibility Changes Coming On The iPhone X The new iPhone X has an edge-to-edge screen and no Home Button, but will be using the Sleep/Wake button on the upper right hand side instead for functions such as the triple click feature for accessibility users and initiating Siri commands. Although we have yet to get our hands on the device to test accessibility features for VoiceOver users, Sighted users can wake the iPhone X by tapping on the screen. Users can then access the home screen by swiping up from the bottom of the phone. Switching between apps also requires swiping up from the bottom of the displays. Additionally, users can switch between apps by swiping from the bottom left of the phone. Unlocking the phone is done with the company new Face ID technology. The phone will remain locked until the iPhone X is able to see the user and positively identify their face using the phone’s TrueDepth camera system. We reached out to Apple on how VoiceOver users will be accommodated on the iPhone x and this is what they told us: "The iPhone X has been designed with a number of accessibility features to support its use. An Overview Of the Apple Event Apple announced this fall’s additions to their hardware lineup. They unveiled the Series 3 Apple Watch, a 4K version of the Apple TV, the iPhone 8 and 8+, along with a special iPhone X addition. Cool Picks All-New Element 43-Inch 4K Ultra HD Smart LED TV - Fire TV Edition LG HBS-910 Tone Infinim Bluetooth Stereo Headset - Black Bank of America Mobile Banking Monster Blaster Boombox Wireless Speaker

In this week’s VIP, Nelson and James are joined by Jeff Thompson from Blind Abilities and Randy Rusnak from ACB Radio. They discuss the top stories from Apple’s Keynote Event and give you some Cool Picks and tips. Top Stories Accessibility Changes Coming On The iPhone X The new iPhone X has an edge-to-edge screen and no Home Button, but will be using the Sleep/Wake button on the upper right hand side instead for functions such as the triple click feature for accessibility users and initiating Siri commands. Although we have yet to get our hands on the device to test accessibility features for VoiceOver users, Sighted users can wake the iPhone X by tapping on the screen. Users can then access the home screen by swiping up from the bottom of the phone. Switching between apps also requires swiping up from the bottom of the displays. Additionally, users can switch between apps by swiping from the bottom left of the phone. Unlocking the phone is done with the company new Face ID technology. The phone will remain locked until the iPhone X is able to see the user and positively identify their face using the phone’s TrueDepth camera system. We reached out to Apple on how VoiceOver users will be accommodated on the iPhone x and this is what they told us: "The iPhone X has been designed with a number of accessibility features to support its use. An Overview Of the Apple Event Apple announced this fall’s additions to their hardware lineup. They unveiled the Series 3 Apple Watch, a 4K version of the Apple TV, the iPhone 8 and 8+, along with a special iPhone X addition. Cool Picks All-New Element 43-Inch 4K Ultra HD Smart LED TV - Fire TV Edition LG HBS-910 Tone Infinim Bluetooth Stereo Headset - Black Bank of America Mobile Banking Monster Blaster Boombox Wireless Speaker

The corticotropin-releasing hormone (CRH) is widely recognised as the major activator of the hypothalamic-pituitary-adrenocortical (HPA) axis, thereby mediating neuroendocrine, autonomic, and behavioural responses to stress. Dysregulation of the release of stress hormones, caused by excessive CRH secretion from the hypothalamus, is frequently observed in patients with affective disorders such as depression. One of the cardinal symptoms of major depression is a severe impairment of sleep (e.g. reduced sleep intensity, disinhibition of rapid eye movement sleep (REMS), and early morning awakenings). Consequently, besides a role of CRH in stress-induced arousal, its additional contribution to spontaneous sleep-wake regulation was suggested in literature. Due to the lack of highly specific CRH receptor antagonists and adequate CRH receptor knockout animal models, the mechanism and pathways by which CRH communicates its arousal function remained indistinct. Up to now it is unclear whether CRH interferes with sleep by a direct central action, or if the activation of the HPA axis and the subsequent release of peripheral stress hormones are mandatory. The present study with conditional CNS-specific CRH receptor type 1 (CRH-R1 CKO) and conventional CRH receptor type 2 knockout mice (CRH-R2 KO), allows assessment of CRH effects on wakefulness and sleep separately from a functional HPA axis together with various levels of CRH receptor system functionality. In addition, challenging sleep homeostasis in these mouse lines by sleep deprivation allows investigating the involvement of CRH and its receptor system in basic sleep-wake regulatory processes. Besides slight dissimilarities between the baseline sleep profiles in the various genotypes, CRH-R1 CKO displayed a markedly different response to intracerebroventricular (i.c.v.) CRH injections. The dose-dependent increases in wakefulness and decreases in non-REM sleep (NREMS), which could be observed in all other mouse lines, were almost totally absent in CRH-R1 CKO. The dose-dependent REMS suppression on the other hand persisted in all, even CRH-R1 CKO, animals. This suggests that the centrally expressed CRH receptor type 1 (CRH-R1) but not the CRH receptor type 2 (CRH-R2), mediates the crucial effects of CRH on wake induction and NREMS suppression. Since REMS inhibition by CRH still occurred in CRH-R1 CKO animals pretreated with a highly specific CRH-R2 antagonist, the clear role of central CRH and both receptors in REMS suppression remains elusive. Sleep deprivation induced significant increases in plasma corticosterone levels in all mouse lines, demonstrating HPA axis activation and suggesting that all mice perceived sleep loss as a stressor. After termination of sleep deprivation, all animals responded with a significant increase of slow wave activity (SWA), an indicator of sleep intensity, followed by a rebound of NREMS. With the exception of CRH-R1 CKO mice, all mice furthermore similarly displayed REMS rebound. Another difference in response to sleep deprivation constitutes the course of SWA in CRH-R1 CKO which was significantly increased over baseline levels for a longer period as compared to all other mouse lines. Accordingly CRH-R1 CKO animals presumably sleep more intensely or efficiently than mice of the other breeding lines. These results suggest that CRH mediates the effects, at least the stressful component, of sleep loss, and moreover that CRH-R1 is essentially involved in sleep homeostasis. This study is the first to show considerable evidence for a crucial involvement of central CRH and CRH-R1 in arousal and the suppression of NREMS. It could further be shown that activation of the HPA axis is not a prerequisite of these effects. Additionally, the action of central CRH, mediated by CRH-R1 seems to influence sleep quality. The role of CRH-R2 has to be regarded as of a minor nature. The impact of CRH on REMS regulation demands further investigation.

Join the faculty from the "The Complexities of Managing Patients with Sleep-Wake Disorders: The Need to Treat the Whole Patient" neuroscienceCME Live and On Demand broadcast as they answer additional audience questions in an informal Q&A session.

The Complexities of Managing Patients with Sleep-Wake Disorders: The Need to Treat the Whole Patient - PDF Course Materials

Patients with sleep-wake disorders such as obstructive sleep apnea, shift work sleep disorder, and jet lag disorder are complex in their presentation and pose significant therapeutic challenges. Sleep-wake disorder patients often present with the symptom of excessive sleepiness and although highly prevalent and detrimental to the patient, society, and the healthcare system, excessive sleepiness remains under-recognized as well as not appropriately managed. Both patients and physicians often view sleepiness as a normal phenomenon; patients may not mention it, and if they do, physicians may not view it as a serious symptom in need of further attention. In part, the difficulty may arise from the fact that patients often do not complain of excessive sleepiness but instead may use terms like fatigue, tired, and lack of energy that may not raise clinical concern or may lead to misdiagnosis (e.g., depression) and inappropriate treatment. In some cases, patients may report problems with their memory or concentration, or automobile crashes. In fact, patients often do not mention anything at all unless some consequence has ensued, like an automobile crash. In this neuroscienceCME Live and On Demand activity, the expert faculty will examine the challenges of sleep-wake disorders from the primary care and sleep specialist perspective with the goal of providing tools for improved recognition, assessment, and coordinated care of the whole patient.

Learning in Hand: iPods Episode #18: iPod touch Basics shows the fundamentals that iPod touch and iPhones users should know. Items in this episode:iPod touch runs the iPhone Operating System that is currently at version 3.0, Sleep/Wake buttons, Slide to unlock, Touchscreen information, Home screen organization, Selection of text, Copy & paste, Setting up Wi-Fi internet access, Turning off keyboard clicks, and Apple's 100+ page iPod touch manual. Go to a web app user guide in iPod touch's Safari at help.apple.com/ipodtouch.

Discover the key to waking up rejuvenated with "Sleeping Sounds," offering 30 minutes of deep sleep enriched with tranquil tunes to enhance melatonin production. Immerse yourself in a world of calming melodies expertly crafted to soothe your mind and body into a restful slumber. Experience the magic of melatonin-boosting music, ensuring a more revitalizing and refreshing wake-up. Join us on this transformative journey to improve your sleep quality and embrace each day with renewed energy. Tune in now and unlock the harmonious gateway to a well-restedand rejuvenated self.--- Send in a voice message: https://podcasters.spotify.com/pod/show/sleeping-sounds1/messageAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy