Podcasts about ucl great ormond street institute

Lucinda Rouse shadows Charlotte Holmes, head of philanthropy at Leukaemia UK, to experience the day-to-day realities of a job in major donor fundraising.Charlotte outlines the range of approaches used to identify connections and nurture relationships with existing and potential donors, from individuals to trusts and foundations and corporate partners. She describes her career path, starting in the box office at Chelsea Football Club, and shares tips for anyone seeking to enter the philanthropy world. Lucinda follows Charlotte during preparations for the charity's flagship fundraising event, Who's Cooking Dinner? at The Dorchester hotel, and joins a staff and supporter visit to the UCL Great Ormond Street Institute of Child Health. There she speaks to Dr Noelia Che, whose research fellowship is funded by Leukaemia UK, and Professor Owen Williams, head of the institute's cancer section.Lucinda is joined by Third Sector's editor, Emily Burt, to reflect on the visits and consider the wider climate for major donor giving. Do you have stories of people whose lives have been transformed for the better thanks to your charity? If so, we'd like to hear them! All it takes is a short voice message to be featured on this podcast. Email lucinda.rouse@haymarket.com for further information.Tell us what you think of the Third Sector Podcast! Please take five minutes to let us know how we can bring you the most relevant, useful content. To fill in the survey, click here.Read the transcript. Hosted on Acast. See acast.com/privacy for more information.

Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Conor McCann from the Department of Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London, UK and Dr Anestis Tsakiridis from the School of Biosciences, The University of Sheffield, Sheffield, UK on the paper "Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue" published in paper copy in Gut in September 2024. Please subscribe to the Gut podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/3UOTwqS) or Spotify (https://spoti.fi/3Ifxq9p).

Join Research Development Manager, Kate Arkell as she speaks to our latest research grantees about their projects. PhD studentship: Dr Matteo Rizzi, UCL Institute of OphthalmologyInvestigating photopsia and photophobia in Stargardt disease. PhD studentship: Chloe Brotherton, Edinburgh UniversityUnderstanding why different RPGR gene mutations can lead to different diagnosis. PhD studentship: Gabriel Velichkova, UCL Institute of OphthalmologyInvestigating Stargardt disease as a target for gene repair. Professor Jacqueline van der Spuy, UCL Institute of OphthalmologyThe consequences of toxic accumulation of a molecule called cGMP in Leber congenital amaurosis (LCA). Professor Jane Sowden, UCL Great Ormond Street Institute of Child HealthRestoring some vision at the later stages of sight loss in advanced retinitis pigmentosa (RP) using a stem cell patch.

Gene therapy is gaining momentum as a noteworthy adversary to cancer, and we are thrilled to be joined today by one of the pioneers of immune system-based treatments. Professor Waseem Qasim applies his craft at the UCL Great Ormond Street Institute of Child Health, which is notorious for being the largest concentration of children's health research in Europe. Professor Qasim explains why he pursued a career in gene therapy, how three patients and technological advancements formed the basis of his groundbreaking treatments, what he thinks about autologous and allogeneic therapies, and what he has to say about his work being linked with a cure for cancer. We learn about the rapid advancement of medical technology, how accessible this technology is to disadvantaged communities, why pricing gene therapies is a slippery slope, and the factors that could lead to a cost reduction in Prof. Qasim's treatments. To end, our guest shares advice on how to merge foundational research and practical applications, why the health industry needs to do more in supporting foundational research, and what Prof. Qasim thinks about the advent of artificial intelligence (AI) in medicine. “[Soon] there will be specific conditions and circumstances where these technologies will give you a deep clearance and a possible complete eradication [of cancer], where the problem just doesn't come back.” — Waseem Qasim Key Points From This Episode: Introducing today's guest, Professor of Cell and Gene Therapy, Waseem Qasim. What led Prof. Qasim to focus on developing gene therapies for genetic disorders in children. The story for Leila Richards's groundbreaking gene-edited cell therapy. How technological innovations have paved the way for successful gene therapies. The details behind Prof. Qasim's second highly-publicized success story: Alyssa. More about his lesser-known patient who bridged the gap between Leila and Alyssa. Our guest explains the quality assurance process before cells are reentered into the body. What he thinks about autologous cell therapies versus allogeneic ones. Prof. Qasim reacts to his work being described as synonymous with a cure for cancer. What he thinks about the radical progression of health technology and whether it will continue to advance at such blinding speed. How accessible this advanced technology is and will be to disadvantaged communities. Why one size does not fit all when it comes to costing and pricing gene therapies. Exploring the factors that could reduce the cost of Prof. Qasim's treatments. Some advice on how to blend the worlds of foundational research and practical application. The role that the health industry should be playing in supporting foundational research. Our guest's thoughts on the use of AI in new medical technologies and techniques.

The assignments students do in STS modules today are nothing like what they used to be. These days, they build portfolios with all sorts of things: short writing, long writing, posters, blogs, in-class presentations. Add to these, projects like podcasts, film clips, campaign strategies, briefing papers, debates, and proposals. Research of different kinds. Creativity. And Challenge. We diversify our curriculum because we know the future for our students holds work as varied as we can imagine. Today's episode offers a sampler of student-made podcasts. These were created by year 3 undergraduates in our science journalism module, run by Dr Jean-Baptiste Gouyon. The assignment is straightforward: create a three-minute news feature about a recent piece of research at UCL. The piece must be suitable for use on as a news segment for radio or podcast. Students start with a recent press release from the UCL Press Office, and they go from there. The piece must include a short interview segment with a researcher. They have a tight deadline, and they have to work pretty much with the tools they have through a laptop and phone. This is real world work as a freelance journalist. For today, I've brought together eight of the ones I like a lot. They're varied, and they deliver the assignment is different ways. Think of it as a sampler. The whole syllabus for HPSC0107 Science Journalism: https://www.ucl.ac.uk/sts/sites/sts/files/hpsc0107-science_journalism-syllabus_2022-23.pdf   Tracks   TRACK 1. New X-ray Tech Promises Better Diagnostics for Heart Disease, Gracie Enticknap This newscast introduces a new-to-research x-ray technology called HiP-CT which images organs at multiple scales with better clarity than previously achievable. I discuss HiP-CT with a researcher who is using it to study the evolution of congenital heart disease in blue baby syndrome and children with one heart ventricle. We discuss the aims of his research, and eventual clinical application and hospital usage of this technology, which could have revolutionary benefit to the understanding, diagnosis and treatment of heart diseases. Interviewee: Professor Andrew Cook, Institute of Cardiovascular Science, Zayed Centre for Research Credits: Stock Media provided by baldwinphilly / Pond5   TRACK 2. Covid-19 Impact on Gut Microbiome, Marcus Chow It is well established that the digestive system, its microbiota, and the immune system are linked and influence each other. With COVID-19 coming to an endemic, much of the research interest now lies in how it can shape the microbiota and how the microbiota can influence the patients' symptoms and long term effects. Wong et has investigated how COVID-19 interact with and in the gastrointestinal tract to better understand the implications of disease management, transmission, and infection control. In this article, we review the important gastrointestinal aspects of the disease. Interviewee: Sunny H Wong, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong Credits: None   TRACK 3. Marketing Infant Formula against Breast Feeding, Nadya Rauch Let's take a critical look at infant formula marketing, which the WHO recently condemned for misleading parents and undermining breastfeeding. Breastmilk has key benefits for infants that can't be replicated in formula milk, such as stems cells and antibodies that help protect infants from infection. We talk to infant formula expert Dr. Fewtrell from UCL's Great Ormond Street Institute of Child Health to debunk some myths on whether infant formula can improve cognitive outcomes for children. Interviewee: Dr. Mary Fewtrell, UCL Great Ormond Street Institute of Child Health Credits: Intro/outro music produced by Leo Daiji Waltmann  “The Wonder of Baby SMA PRO Follow on Milk," https://www.youtube.com/watch?v=0RDGFnermSc&ab_channel=LacaraChildModelandTalentAgency   TRACK 4. New guidelines on the diagnosis and treatment of endometriosis, Sofia Sancho The European Society of Human Reproduction and Embryology have recently released 200 pages of new, comprehensive guidelines for the diagnosis of endometriosis. A major change in the new version is that laparoscopy is no longer deemed the gold standard for diagnosis, which will lead to more patients being accommodated for, and hopefully the long wait for diagnosis being decreased. I speak to Dr Ertan Saridogan, who co-authored the new guidelines, about their significance and how they can lead to improvements in endometriosis research. Interviewee: Dr Ertan Saridogan, UCL Hospital and UCL Institute for Women's Health Credits: Cool Jazzy Brass & Vibraphone by M33 Project, licensed under CC BY 4.0   TRACK 5. Minimally invasive image-guided ablation (MINIMA), Yingnan Chen Proof-of-concept for MINIMA is recently published. Compare to traditional ways of removing tumours, MINIMA is not as invasive and has fewer side effects, hence, the patients can recover quicker. Moreover, MINIMA can preserve the function of infected organ as much as possible. I have invited the lead author, Rebecca Baker, to talk about how MINIMA works and its potential as a cancer treatment. She also discussed the limitations and what needs to be done before moving on to clinical trials. Interviewee: Rebecca Baker (PhD Student at UCL Centre for Advanced Biomedical Imaging) Credits: Inspiring Electronic https://elements.envato.com/inspiring-electronic-BHYUADP. License Code: 9WXPUERVK7   TRACK 6. Covid's impact on student experience at UCL, Juwairiyah Aftab The podcast explores a research study conducted by Dr Waugh, alongside other individuals, titled ‘Impacts of the Covid‐19 pandemic on the health of university students'. The study, based at University College London (UCL), explores the physical and mental health consequences of the pandemic on students, with mention of the importance of this study and its relevance. Furthermore, the study mentions cases of racism and discrimination, followed by an evaluation of how trustworthy the research is and brief future recommendations. Interviewee: Dr Mark Waugh, UCL Department of Education, Division of Medicine, UCL Faculty of Medical Sciences Credits: Statistics from the National Student Survey (NSS) https://www.officeforstudents.org.uk/media/1480/insight-brief-10-nss-finalforweb.pdf Background music (no copyright) https://www.youtube.com/watch?v=BQ6gUSJARIA   TRACK 7. How Do We Slow Non-Alcoholic Fatty Liver Disease, Eloise Jarvis Dr Toryn Poolman talks about non-alcoholic fatty liver disease (NAFLD), leading cause of liver transplants that effecting up to one-third of the British population. It's a medical condition that's on the rise owing to changes in diet: more sugar, more alcohol, and more processed foods. He explains what NAFLD is, what it can progress to, what the causes are, and how it can be avoided or reversed. Interviewee: Dr Toryn Poolman, Department: Structural and Molecular Biology, UCL Division of Biosciences Credits: Bensound.com   TRACK 8. Applied Linguistics studying pain descriptions associated with endometriosis, Dan Sharpe Listening more carefully to the words patients choose to describe their symptoms can help doctors identify more complex medical conditions, says Zsófia Demjén. She reports on new research into specific patterns of words patients use to describe their symptoms. This might lead to earlier diagnosis of endometriosis and other serious chronic conditions. Just listening more carefully can make all the difference. Interviewee: Zsófia Demjén, Associate Professor of Applied Linguistics, UCL Centre for Applied Linguistics Credits: Details to come   Host Professor Joe Cain Professor of History and Philosophy of Biology https://ucl.ac.uk/sts/cain   Music credits Intro and Exit music “Rollin At 5,” by Kevin MacLeod https://filmmusic.io/song/5000-rollin-at-5 License: http://creativecommons.org/licenses/by/4.0 “Silly Intro,” by Alexander Nakarada https://filmmusic.io/song/4786-silly-intro License: http://creativecommons.org/licenses/by/4.0/ Both are available on the website: filmmusic.IO   Podcast information WeAreSTS is a production of the Department of Science and Technology Studies (STS) at University College London (UCL). To find out more, or to leave feedback about the show: https://www.ucl.ac.uk/sts/podcast This site also includes information for how STS students and staff can get involved with our programme. Editing and post-production by Professor Joe Cain, unless otherwise noted. WeAreSTS producer is Professor Joe Cain. Twitter: @stsucl #WeAreSTS

Speaking before their keynotes at the BABCP 2022 Annual Conference, Roz Shafran and Adam Radomsky talk about OCD, Control, Doubt, Perfectionism & CBT. Roz Shafran, UCL Great Ormond Street Institute of Child Health., London , UK Too good for your own good? Advances in the understanding and treatment of clinical perfectionism. Adam Radomsky, Concordia University Montréal, Canada Making CBT for OCD better one experiment, one belief, one step at a time. The 50th Annual BABCP Conference will take place in London on 20-23 July 2022: babcp2022.org/

Professor Monica Lakhanpaul, (UCL Great Ormond Street Institute of Child Health) and Dr Priti Parikh (Bartlett School of Sustainable Construction) are joined by Professor Mamokgethi Phakeng in South Africa to talk about how the UN Sustainable Development Goals can be adapted and achieved throughout Africa. Professor Phakeng is the Vice-Chancellor of the University of Cape Town and is a huge advocate of the SDGs. She shares how the SDGs are perceived in South Africa, concentrating on areas of education and research. For more information and to access the transcript: www.ucl.ac.uk/sustainable-development-goals/unlocking-sdgs-blueprint-future-episode-1-part-2 Date of episode recording: 2022-04-25 Duration: 00:30:43 Language of episode: English Presenter: Professor Monica Lakhanpaul; Dr Priti Parikh Guests: Professor Mamokgethi Phakeng Producer: Front Ear Podcasts

Co-hosts Professor Monica Lakhanpaul, (UCL Great Ormond Street Institute of Child Health) and Dr Priti Parikh (Bartlett School of Sustainable Construction) delve into the impact that the pandemic has had on the UN Sustainable Development Goals. Joining them are Professor Anthony Costello and Dr Rochelle Burgess (both UCL Institute for Global Health), who offers their perspective on how the World Health Organisation has addressed some of the SDGs, and how the COVID-19 pandemic has changed how we might respond to the SDGs. For more information and to access the transcript: www.ucl.ac.uk/sustainable-development-goals/unlocking-sdgs-blueprint-future-episode-1-part-1 Date of episode recording: 2022-04-25 Duration: 00:23:03 Language of episode: English Presenter: Professor Monica Lakhanpaul; Dr Priti Parikh Guests: Professor Anthony Costello; Dr Rochelle Burgess Producer: Front Ear Podcasts

Professor Monica Lakhanpaul, (UCL Great Ormond Street Institute of Child Health) and Dr Priti Parikh (Bartlett School of Sustainable Construction) chat to Dr Kate Roll (UCL Institute for Innovation and Public Purpose) about sustainable development. Dr Roll explores what the UN Sustainable Development Goals (SDGs) really mean, where they come from, and why they exist at all. For more information and to access the transcript: https://www.ucl.ac.uk/sustainable-development-goals/unlocking-sdgs-blueprint-future-episode-0 Date of episode recording: 2022-04-25 Duration: 00:11:40 Language of episode: English Presenter: Professor Monica Lakhanpaul, Dr Priti Parikh Guests: Dr Kate Roll Producer: Front Ear Podcasts

Topic discuss: "Childhood obesity" and "Ramadhan: make lifelong changes" Presenter: Raheel Ahmad Safeer Zartasht Khan Childhood obesity Is childhood obesity taken seriously? Clearly not, with numbers on the rise and costs to the NHS at around £6.1 billion who is to blame for not stepping up to do more? What are the barriers and how can we create a healthier future for children so they are thriving, not just surviving? Ramadhan: make lifelong changes Ramadan is a blessed month that gives us a chance every year to spiritually, morally and physically reform ourselves not only for just a month but to continue the good deeds and incorporate good habits in our life. Join us as we discuss how to use Ramadan as a spiritual reset that drives a real reformation in ourselves to goodness. Guests include: Dr Helen Croker- Helen is a Registered Dietitian and has a PhD in epidemiology and public health from UCL. Laura Basterfield- Laura is a Research Associate in the Population Health Sciences Institute at Newcastle University Simon Russell- Dr Simon Russell is a Senior Research Fellow and Unit Manager of the NIHR Policy Research Unit in Obesity at the UCL Great Ormond Street Institute of Child Health Producers: Cemal Inam Noor Us Sabah

My blood pressure is perfectly normal, but could I benefit from medication to lower it even further? We discuss with Oxford University's Prof Kazem Rahimi and our resident GP Margaret McCartney. How do you diagnose a new disease that could have 200 symptoms? We explore long Covid in children with our reporter Carolyn Atkinson and Professor Sir Terence Stephenson from the UCL Great Ormond Street Institute for Child Health. PRESENTER: James Gallagher PRODUCER: Beth Eastwood

Our lives are framed by numbers tracking our performance in school, our financial health, and our physical and emotional wellbeing. While this information can help us figure out what we might do to improve a situation, it's only part of the statistical story. There's other information, other data, that might be useful as well. The importance of linking data is the focus of this episode of Stats and Stories, where we explore the statistics behind the stories and the stories behind the statistics with guest Katie Harron Harron is an Associate Professor in quantitative methods at the UCL Great Ormond Street Institute of Child Health as well as the 2021 Wood Medal recipient for, “her outstanding methodological work on record linkage.” . Her research focuses on the development of statistical methods and synthetic data for data linkage, and particularly for evaluating the quality of linkage. She aims to develop methods to exploit the rich data that are collected about populations as we interact with services throughout our lives. Her work facilitates the wider use of these population-based administrative and electronic data sources for epidemiological research, to support clinical trials, and to inform policy. Herron's applied research focuses on maximizing the use of existing data sources to improve services for vulnerable mothers and families. Her current research links data from health, education and social care at a national level, in order to improve our understanding of the health of individuals from birth to young adulthood.

UK research has found that children on a vegan diet are more likely to be shorter and have weaker bones than their meat-eating peers.The study by the UCL Great Ormond Street Institute of Child Health in the UK and the Children's Memorial Health Institute in Poland compared infants on a vegan diet and those who were omnivores.It found that vegan kids might have slightly lower levels of cholesterol and body fat - but on average they were three centimetres shorter, had weaker bones and were three times more likely to be B12 deficient.To discuss this, Claire Insley media spokesperson for the Vegan Society New Zealand joined Kerre McIvor.LISTEN ABOVE 

The Beat podcast is designed for healthcare professionals and is brought to you by Nutricia. In this four-part miniseries The Beat focuses on epilepsy and the options for managing uncontrolled seizures when medication doesn't work. In this episode, Specialist Ketogenic Dietitian, Susan Wood, at Matthew's Friends Clinics, discusses the history of anti-seizure medications, their potential side effects and risks of uncontrolled seizures with Professor Helen Cross OBE. Professor Helen is The Prince of Wales's Chair of Childhood Epilepsy and Head of the Developmental Neuroscience Programme at UCL-Great Ormond Street Institute of Child Health, Honorary Consultant in Paediatric Neurology Great Ormond Street Hospital for Children NHS Foundation Trust, London and Young Epilepsy, Lingfield, UK. 

During the rule of the Ottoman Empire, some of the early Baha'is made the long pilgrimage from Persia to Akka to attain the presence of Baha'u'llah, the Founder of the Baha'i Faith. Haji Mulla Mehdi of Yazd was one such pilgrim, who in the company of his two sons, took the arduous journey on foot to pay homage to his Beloved. This journey of love enflamed the spirit of sacrifice and service in the hearts of Haji Mulla Mehdi's descendants, giving rise to three Hands of the Cause of God, and two Trustees of Huquq'u'llah across three generations. This is the story of their journeys. Faraneh Vargha-Khadem is one of the 22 great, great, grandchildren of Haji Mulla Mehdi Yazdi, and one of the three daughters of the late Hand of the Cause of God, and Trustee of Huquq'u'llah, Dr Ali Muhammad Varqa. Professionally, Faraneh is Professor of Cognitive Neuroscience at the UCL Great Ormond Street Institute of Child Health in London, UK. She is also the Clinical Academic Lead for the Department of Neuropsychology at Great Ormond Street Hospital for Children. Her research is focused on early brain injury and the development of brain circuits that underpin human attributes, such as episodic memory, and speech and language. She was part of the team that identified the FOXP2 gene, the so-called “speech gene” that may explain why humans talk and chimps do not! She is also credited with the discovery of the amnesic syndrome in children. To view the video visit our YouTube channel https://youtu.be/wy0TJyMlChs

Helen Mirren tells us about her new film the Good Liar and why even she has fallen for a scam. We talk about a DIY home urine or swab test currently being trialled as an alternative to the cervical smear with Imogen Pinnell from Jo’s Cervical Cancer Trust Line. We hear from two female police officers about their difficulties reporting allegations of domestic abuse against their partner who also works for the police. The human rights lawyer and founding director of the Centre for Women’s Justice, Harriet Wistrich talks about launching an official Super-Complaint where repeated allegations of 16 cases of domestic abuse where made only for the cases to be dropped. We discuss the safety of vaccinations with Professor Helen Bedford from UCL Great Ormond Street Institute of Child Health, Professor Adam Finn a Professor of Paediatrics at the Bristol Children’s Vaccine Centre and from Dr Tonia Thomas from the Vaccine Knowledge at Oxford University. Rising soul artist Celeste talks about her music and the support of BBC Introducing. She performs her new single, Strange. Father and daughter Mark and Emily Simmonds talk about overcoming mental illness and their book Breakdown and Repair.

We’re used to hearing about the negative impact that using social media can have on girls – it can cause sleeplessness, low mood, depression and anxiety. Edwina Dunn, a data entrepreneur and founder of the educational charity The Female Lead, thinks differently. She believes that used in the right way, social media can be a force for good and can improve teenagers’ mental health. She joins Jenni to explain her theory and the research she commissioned from Cambridge University, along with Dr Anne-Lise Goddings, Clinical Lecturer at UCL Great Ormond Street Institute of Child Health.

We hear from the woman known, until recently, as Emily Doe. Chanel Miller was sexually assaulted while she was unconscious on the ground on Stanford University campus in the USA. Her Victim Impact statement which she addressed to her attacker Brock Turner was published on Buzzfeed and was viewed online by eleven million people within four days. In her memoir is titled Know My Name - she explains why. Following the death of a new born baby in a cell at Bronzefield prison in Surrey, we talk to Deborah Coles, the director of Inquest about what the overarching investigation will need to do, to help prevent further tragedies in women's prisons. Edwina Dunn, a data entrepreneur and founder of the educational charity The Female Lead, believes that social media can be used to improve teenagers’ mental health. She explains how - and we hear from Dr Anne-Lise Goddings, Clinical Lecturer at UCL Great Ormond Street Institute of Child Health. And, Fuchsia Dunlop explores the flavours of Sichuanese cuisine - known for its liberal use of chillies and Sichuan pepper. Presenter: Jenni Murray Producer: Ruth Watts

Measles cases in Europe have tripled between 2017 and 2018. It's the highest number recorded this decade, according to the World Health Organisation and in America, two states are experiencing an outbreak of measles. Jane is joined by Helen Bedford, Professor of Children's Health at UCL Great Ormond Street Institute of Child Health and Samantha Vanderslott, social sciences researcher at Oxford Vaccine Group to discuss parental attitudes to vaccinating children.

Head coach of the England netball team, Tracey Neville tells us about her work to get netball recognised as a professional sport.New research shows almost two thirds of those who left the Bar on the Western Circuit over the last six years were women. Why is it so difficult for women to progress in a career as a barrister? We hear from Sarah Langford who specialises in criminal and family law and Arlene Small, a specialist in family finance and children work. Cases of measles in Europe have tripled between 2017 and 2018 the highest recorded this decade according to the World Health Organisation. Helen Bedford, Professor of Children's Health at UCL Great Ormond Street Institute of Child Health and Samantha Vanderslott a social sciences researcher at Oxford Vaccine Group discuss the recent outbreaks in America and why some parents are reluctant to get their children vaccinated.The day before Valentine's Day has now become Galentine's Day, a day to celebrate female friendships. Claire Cohen Women's Editor at the Daily Telegraph and Rachel Pashley a marketing consultant and the author of New Female Tribes discuss the marketing of gal pals.Breast ironing is a way to stop teenagers' breasts from growing. It's painful but mothers in some communities call it tradition and believe it will protect their daughters from sexual assault. It happens in some African countries but has been recorded in the UK too. Milly Kerr from the National FGM Centre tells us what the UK government is doing to tackle this form of child abuse. The textile artist Clare Hunter tells us about the importance of sewing when it comes to protest banners and story telling tapestries.Fran Thomas, who can have up to 15 epileptic fits a day, tells us how her seizures are linked to her menstrual cycle. Dr Simona Balestrini, an epilepsy expert, explains why new research should bring better and new treatment options to women.Presented by Jenni Murray Produced by Rabeka Nurmahomed Edited by Beverley Purcell

Chair in Translational Psychology at the UCL Great Ormond Street Institute of Child Health discusses active innovation and scrutiny of future psychological treatments research.

Helena is interested in the functional effects of genetic variation in human induced pluripotent stem cells (iPSC). Her research combines computational and experimental methods in iPSC-based models to understand the cellular mechanisms that lead to rare human diseases. Helena is a human geneticist who leads a research group at the UCL Great Ormond Street Institute of Child Health. She is a MRC eMedLab career development fellow (www.emedlab.ac.uk) and holds an appointment also at the Wellcome Trust Sanger Institute. Helena received her PhD from the University of Helsinki, where she studied the genetic mechanisms underlying autism spectrum disorders. She then transitioned to functional genomics, using diverse next-generation sequencing -based assays to study how DNA sequence variation influences different levels of gene regulation in human cells, first at the University of Geneva, and then at the EMBL-EBI. She joined the Human Induced Pluripotent Stem Cells Initiative (www.hipsci.org) in 2014 and has since focused on the functional characterization of genetic variation in human iPS cells from hundreds of donors. The long-term goal of her research is to combine high-dimensional molecular data from iPSCs and iPSC-derived cell types with clinical data to comprehensively model the cellular mechanisms that lead to rare human diseases.