Podcasts about cgmp

Send us a textSchedule an Rx AssessmentSubscribe to Master The MarginWhat does it really take to start and sustain a successful compounding pharmacy in 2026? In this episode, Scotty Sykes, CPA, CFP®, and Austin Murray sit down with Amy Summers, PharmD, BCSCP and of Restore Health Consulting, to discuss how pharmacy owners can move from idea to implementation when entering the compounding space.We cover:Designing a purpose-built facility for USP standards and your product mixThe mindset shift from dispensing to creating and how to balance quality with patient careMarket analysis, relationships, and niche focus in building a sustainable businessKey trends driving growth, consolidation, and private investment in the compounding industryMore About Our Guest:Amy Summers, PharmD, BCSCP is an independent consultant, specializing in business, operations, quality assurance, and regulatory compliance matters for the pharmaceutical compounding industry. She earned her PharmD degree from the University of California San Francisco and was among the first pharmacists in the nation to earn a Board Certified Sterile Compounding Pharmacist (BCSCP) credential. Dr. Summers has spent her entire career as a pharmacist in various settings centered around non-sterile and sterile compounding. She has formerly served as Director of Operations and Pharmacist in Charge at organizations engaged in compounding and also as Managing Director of a FDA-registered 503B outsourcing facility. With extensive experience in USP standards, accreditation, cGMP, and regulatory compliance, Dr. Summers has also served as an expert witness for matters related to compounding.Stay connected with Amy and Restore Health Consulting: Amy Summers LinkedInRestore Health Consulting WebsiteRestore Health Consulting LinkedInStay connected with us on social media:Facebook: https://www.facebook.com/sykesandcoTwitter: https://twitter.com/OllinSykesLinkedIn: https://www.linkedin.com/company/sykes-&-company-p-a-?trk=tyahScotty Sykes – CPA, CFP® LinkedIn: https://www.linkedin.com/in/scottysykes/More on this topic:Podcast: The Trusted Pharmacist: Advocacy and Building a Resilient PharmacyPodcast: From Counter to Capitol

44% of supplements FAIL testing! Dr. Glenn, Head of Science at SuppCo, reveals which supplements don't contain what they say, how to spot red flags, and why even expensive brands might be lying about what's in the bottle. Learn the 3 essential rules before buying ANY supplement.Think your supplements contain what they claim? Think again. Dr. Glenn, Head of Science at SuppCo, drops a bombshell: 44% of supplements they've tested have failed - meaning they contain less than 95% of the active ingredient listed on the label. Many have ZERO active ingredients at all.In this eye-opening interview, Dr. Glenn exposes the dark side of the $70 billion supplement industry, including creatine gummies on Amazon with no creatine, urolithin A products with less than 1% of the active ingredient, and why products with better reviews often contain nothing at all.Learn which certifications actually matter (NSF, USP, cGMP), the red flags to watch for when shopping, why gummies are particularly risky, and how SuppCo's trust score system helps consumers navigate the overwhelming world of supplements. Plus, get Dr. Glenn's 3 essential tips every supplement buyer needs to know before making their next purchase.

This episode of Off Script: A Pharma Manufacturing Podcast features a conversation with Jana Falkenberg, senior legal counsel and corporate compliance officer at Vetter Pharma, a global contract development and manufacturing organization (CDMO) headquartered in Germany. Falkenberg, who is responsible for the continuous improvement of the compliance management system at Vetter, makes the case that corporate compliance encompasses legal, ethical, and internal standards. At Vetter, which this year is celebrating its 75th anniversary, building trust and fostering an environment of integrity is a critical component of the company's culture and operations as a family-owned business. This episode is sponsored by Vetter Pharma.

Is continuous manufacturing delivering the transformative results everyone promised, or are you being sold an expensive solution to the wrong problem? While industry headlines tout revolutionary productivity gains, the economic reality behind continuous bioprocessing tells a more nuanced story that every process engineer needs to understand before making capital investment decisions.In this episode, host David Brühlmann continues his conversation with Andreas Castan, Strategic Technology and Business Development Leader at Cytiva, diving deep into the hard economics and operational realities of next-generation manufacturing strategies. Andreas brings over 25 years of bioprocess expertise from upstream innovation to cGMP manufacturing scale-up.Here are three critical takeaways from this conversation:Continuous vs Fed-Batch Economics Are Closer Than Expected: Andreas reveals real process economic modeling data showing that while continuous reduces capital costs through smaller bioreactors and facilities, higher media consumption (20-25% of COGS) and operational complexity often balance out the savings. The deciding factor isn't technology elegance but your specific production volume and pipeline needs.Regulatory Approval Isn't Easier Despite FDA Support: Even with regulatory enthusiasm for continuous processing, QA teams still demand the same fundamentals: traceability, batch definition, viral clearance validation, and process characterization. The technology choice should be driven by your business case, not regulatory preferences.Sustainability Benefits Are Modest: Contrary to industry hype, Andreas shares findings showing continuous manufacturing delivers only 20% carbon footprint reduction compared to optimized fed-batch. Real environmental gains come from HVAC efficiency and smaller cleanroom footprints, not inherent process advantages.Ready to cut through the marketing noise and make data-driven manufacturing decisions? This conversation delivers the unvarnished truth about when continuous processing creates real value and when intensified fed-batch might be your smartest investment.Connect with Andreas Castan:LinkedIn: www.linkedin.com/in/andreas-castan-91570b1Cytiva landing page: Process intensificationOnline tool: Process intensifierNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call

Shawn Tierney meets up with Lauton Rushford of Endress+Hauser to learn about new innovations in Coriolis Flowmeter Technology in this episode of The Automation Podcast. For any links related to this episode, check out the “Show Notes” located below the video. Watch The Automation Podcast from The Automation Blog: Listen to The Automation Podcast from The Automation Blog: The Automation Podcast, Episode 247 Show Notes: Special thanks to Endress+Hauser for sponsoring this episode so we could release it “ad free!” To learn about Endress+Hauser, and Coriolis Flowmeters, checkout the below links: Learn more about Endress+Hauser Learn more about flowmeter products Read the transcript on The Automation Blog: (automatically generated) Shawn Tierney (Host): Welcome back to the automation podcast. Shawn Tierney here from Insights and Automation, and I wanna thank you for tuning back in. This week on the show, I meet up with Lawton Rushford from Endress and Hauser to learn all about the latest innovations in Coriolis flow meters. And I also wanna thank Endress and Hauser for sponsoring this episode so I could bring it to you completely ad free. With that said, if you’re interested in learning about what’s the latest in technology used in Coriolis flow meters, I think you’ll enjoy this episode. I know I did. And with that, let’s go ahead and jump right into this week’s show. I wanna welcome to the show, Lawton from Endress and Hauser. Lawton, it’s great to have you on. This is the first time you’re on the show. We plus, we’ve had your company on before. But, Lawton, if you don’t mind, could you, before we jump into Coriolis flow meters, which is an extremely important technology in our industry, could you first introduce yourself to our audience? Lauton Rushford (E+H): Yeah. Absolutely. Thank you. My name is Lawton Rushford. I am the flow product marketing manager here at Anderson Hauser, based in Greenwood, Indiana, which is about twenty minutes south of Indianapolis, Indiana at our, national headquarters, for Anderson Hauser. I’ve been with Anderson Hauser for seven years now, a whole bunch of different roles, but, for the last three years, I’ve been in this role, a flow marketing manager. Today, I I really wanted to highlight a couple of awesome innovations that we’ve had in Coriolis flow technology, over the last, we’ll see, about year or so, because I think there’s a lot of, use cases and a lot of awesome, insights we can get from from our Coriolis flow meters. And, yeah. So I guess we can we can kick it off. I did wanna highlight Anderson Hauser as the the manufacturer that I work for, and we have a history, a long history of, of innovation. And so I’m gonna kinda highlight that, initially, talk about what sort of portfolio we have currently with our Coriolis flow meters, and then talk about a couple of new cool things that that we have released over the last couple of couple of months. And then finish off with, what we call heartbeat technology. It’s our advanced diagnostic system in all of our flow meters and all of our products across the board. It started with flow. So I think there’s a lot of you cool use cases, and I’ll I’ll highlight a couple of those as well. And then, of course, Shawn is the the audience here. Anytime there’s questions or anything, please feel free to to let me know, and I can I can try and address them as they come up? Shawn Tierney (Host): Sounds good. Yeah. Lauton Rushford (E+H): Awesome. Great. So I guess our first Coriolis meter that we introduced into the market was back in, 1986. So it’s been some time. As you can tell by the the slide here, there’s a lot of different designs of Coriolis flowmeters. There isn’t one right way to do it, but I think that the way that Anderson Houser has approached innovation is is pretty pretty awesome and pretty impressive. Everything from a single tube, design to a dual tube design, dual straight tube design versus a dual bent tube design. There are a lot of different types of Coriolis meters out on the market, and we’ll talk about a couple of, differentiators that we that, Anderson Hauser has on, on some products that we’ve recently released. Shawn Tierney (Host): You know, just by looking at the, the slide here, the one that, like, really attracts my eye is the ProMASS. That’s the one that I I think I’ve seen the most in the field. Lauton Rushford (E+H): Yep. Yep. Shawn Tierney (Host): You know, walking around the different plants, and, that was launched in 1998. So that’s been out for quite some time. So just wanted to throw that out there for those listening. That may be the one you’ve seen the most of as in your in your travels. Lauton Rushford (E+H): Yeah. Yeah. Definitely. There’s a lot of a lot of ProMasses out there. Our endpoint was the first one, but, shortly after that, we released our ProMasses. And we’ve just been you know, we’ve we’ve had a lot of iterations, which I think is also part of the impressive thing in terms of innovation that Anderson Hauser continues to to to, do in terms of research and development on that. And the one that I always think about is is the the one that kinda looks like a UFO. That is our ProMASS X. It’s a high capacity, large diameter, Coriolis meter with four tubes in there. So it’s kind of bent two separate sys systems and then put together in one, large device, and I always I always think that one’s cool because it kinda looks like a like something out of Star Wars or something. Yep. Yep. So, yep, so I I think that’s that’s really, really cool. There’s a lot of new things that we’ve released, and this is, I mean, this is a short timeline of of some of the innovations that we have. But, you know, over the last year or so, we’ve we’ve definitely invested a little bit more, into specific applications, and that kind of leads us into our entire portfolio of Coriolis flow meters. We have 17 different sensors. So that is not a normal thing in the industry. I I think that to some people, it it can be confusing if you’re looking at them all at the same time, a little overwhelming. But I I think it’s really important that I that I kind of talk about this in terms of every application that we look at. We’re not trying to put one flow meter into that application. We’re taking the application and the requirements of that application and designing a device that’s meant for it. So, in certain applications, you may not have to choose between 17 different sensors. You really have probably two or three that you’re trying to to decide between and weigh, both pressure drop, accuracy, density specifications, things like that that that will ultimately give you the the best meter for that application. But we we don’t wanna take a an approach of trying to, cram a a sensor into an application. We would prefer to design the sensor in and meant for certain applications. So it does I guess there’s two questions on here. Why so many sensors? Well, because we wanna design our our sensors for specific applications. There’s a lot of different applications out there. Doesn’t that make it confusing? Well, of course, it makes it a little confusing if you’re looking at it from from the high level 17 different sensors. But, every application that we look at, we’re we’re trying to, there’s a lot of different requirements of of applications in oil and gas versus life sciences, and we wanted to design sensors that fit the market and fit the application that they’re supposed to go into. And in general, all of them work the exact same way. As a as a general rule of thumb, your Coriolis flow meter measurements are mass flow, density, and temperature as a as a starting point. We’ll talk about a couple of features that we’ve started adding to some of our flow meters that that, create more of a multivariable device. Instead of just measuring those three things, we can add viscosity or, we can do other things or concentration, things like that, with the meters. But in general, the mass flow is is using, the phase shift between your inlet and outlet pickup coils and taking that into account to relate it directly to the amount of mass that’s within those tubes. And then similarly, as the tubes are oscillating, a more dense fluid is going to have a lower resonant frequency. And based around resonant frequencies, we can understand how dense the fluid is inside of the, inside of those flow tubes. And then we also have on every single one of our Coriolis flow meters, PT 1,000, temperature probe that’s attached directly to the inside of the, the outside of the tube within the secondary containment, for additional values, additional multivariable, use uses. I mean, for for example, on a on a concentration measurement, really what you’re using is density and temperature in conjunction, to relate that to a concentration. So that’s something that that we would that that would add to the use cases for for a a Coriolis flow meter. And one of the the current biggest innovations that we’ve had recently is with our our ProMaths queue. The ProMaths queue is a a little bit of a different design than some of the other ProMasses that you may have seen on on some previous slides. We actually, have a little bit, longer tube that’s, has a more harsher bend in it. Mhmm. The reason for that is because what we’re trying to do is we’re trying to oscillate these two sensors or these two flow tubes at two at the same frequency, but in two different modes. So in multiple frequencies, at the same time. So, essentially, what we’re doing is our our historic use of a a pro mass meter is kind of in that that top visual where we’re oscillating in one frequency, and one one specific frequency depending on the fluid that’s going through it. And then on the at the bottom, we show an additional mode of oscillation, so an additional frequency that we’re oscillating at that gives us additional information for, specifically challenging applications. So in in in a lot of these cases, what we what we see in most of these applications is, a lot of whipped products, purposeful entrainment of of air into into, applications. So cement in general, let’s say, as an example, we can start there. Well cement, you’re it’s aerated all the time. So as you are are moving that cement around, air pockets can be filled in inside of that cement and can cause challenges as most things with air cause challenges, especially as as you’re moving into a multiphase fluid. Anytime you have one or more than one fluid phase within the the the meter, the meter can is it’s it’s almost like, the meter is kind of confused. It it’s not really sure what it’s supposed to be reading and what it is reading and why it’s reading that. So with with multi frequency technology, we can actually compensate internally compensate because we’re oscillating in two modes. We can compensate for the air that’s present and give a, a corrected mass flow and a corrected, density. So Right. A lot of milk milk applications, cream cheese, well cement, anything like that. Shawn Tierney (Host): That’s awesome. Could you back up one slide for a second? Sure. Lauton Rushford (E+H): Sure. Shawn Tierney (Host): I just I find this so interesting, but I I know that the audience, not everybody’s on the same page. So I think this would be a great slide. Could you just, like, vary what the basic the basic operation of a Coriolis flow meter is? Okay. We know we’re trying to measure typically the flow rate, the flow rate. Right? And, you know, there’s all these variables that go into it. But could you really just, you know, give us the the introductory, you know, how does this thing work? Lauton Rushford (E+H): Sure. So there are exciters, if if you will, or vibrating electronics that’s going to oscillate those flow tubes. Shawn Tierney (Host): Okay. Lauton Rushford (E+H): And they’re gonna if there’s no flow in it, the oscillation is going to basically be, very in line, in sync. Your tubes are going to move out and then move in. And, again, it’s these are a little exaggerated in terms of videos, but the actual tubes will will start vibrating, almost like a tuning fork or you hit a wine glass on the side of a table and you get the vibration out of the wine glass. That’s kind of the same vibration that’s happening. And now as we start flowing product through those flow tubes, we get these these waves that are created. And the inlet and outlet pickup coil are now not in sync, meaning that we’re using the Coriolis force or we’re essentially looking at a phase shift as those tubes start to create those waves, where where there’s a time difference between the inlet and the outlet pickup coil. And that time difference is ultimately what’s related to phase shift, which is ultimately what’s related to that mass flow that’s inside the tubes. Similarly, as we’re oscillating those tubes, if we have water going through that, those tubes, well, we know what the resonant frequency should be of water. We also know what the resonant frequency is of a more dense or a lighter, less dense fluid. So now we can start understanding what the density is specifically as well. So that’s where kind of the multivariable, measurements happen within the flow tube. But, essentially, all of it’s based around a time measurement. It’s all based around when does this, this pickup coil pick up this tube, and when does this pickup, outlet pickup coil pick up the the tube coming back. Yep. Shawn Tierney (Host): Yeah. And so we talked about the ProMASQ having two modes because when the liquids or, you know, like, the substance, like cement or dairy, you know, cream or whatnot, have a lot of ear in it, that could be a challenge. So you have this other mode. We also talked about having a, the temperature sensor thermocouple built in. Mhmm. Is is temperature always and I know I’m asking a lot of crazy questions here, but is temperature always a factor? Because I can see definitely products operate very differently than based on the temperature. Is temperature always a factor in, coming up with the calculation? Lauton Rushford (E+H): So, typically, temperature is going to affect not only the fluid. It’s also going to affect the properties of the tubes themselves. So that’s something that’s often overlooked. And and when when we’re when we’re looking at applications, yes, we care about what the the the temperature of the fluid is because, the density of that fluid may change. There may be more or less mass flow depending, on, how close a pump is. There’s a lot of installation effects as well. But, ultimately, the the as those tubes are oscillating, if you’re if the temperature is low enough or the temperature is high enough, those tubes are have the potential to move more or less Yeah. As you’re oscillating them. So that’s where temperature plays a really big factor, not only in in measuring temperature, that’s a great added value, but also in the, the thermal, properties of the actual tube’s material themselves. Shawn Tierney (Host): Thank you for taking my questions. I just find this interesting. Lauton Rushford (E+H): Yeah. Oh, that’s that’s great. That’s a great question. That is something that that isn’t really thought about, but, we always we always have to take that into account. And and that’s part of, ensuring that the the stated accuracy, their specifications of the device are met throughout the entire, temperature range of the meter’s specification. So if we know that we’re gonna be operating, this meter is rated for negative 40 degrees f to 300 degrees f, well, we have to make sure that we understand how the tubes will react throughout that entire range. And that’s that again goes back to that innovation that goes back to the research and development that goes into the design of these sensors. So, a lot of important things there. So with that, I guess there’s there’s another added value that that comes into play when, we talk about oscillating that Pro Mask Q at a, at two modes. There’s actually an additional effect that happens to the tubes, And as those tubes because of how long those tubes are, as the tubes start oscillating, at the end of their oscillation, at their maximum amplitude of oscillation, you get a slight twisting motion in the tubes themselves. And so we have a device that is called our ProMass I that directly measures, viscosity directly out of the meter. And that is using a similar, a similar technology in a torsional oscillation mode. Whereas the ProMAS Q, just by nature of design, actually has some slight twisting motions. So, you know, our our r and d g experts and geniuses over, over over overseas, they they came up with this idea. Well, why couldn’t we do a similar thing with our ProMask Q? Why couldn’t we look at how much shear we’re placing on the fluid or how much twisting we’re placing on the on the fluid and understand maybe a little bit more about the individual properties of that fluid that’s going through the meter? And that’s where the oscillation the the torsional oscillation or the rotational oscillation, of that that flow tube can give us a little bit more insight into the viscosity of the fluid itself. And so this is where kind of another innovation, which is on the ProMascue, the hydrocarbon viscosity monitoring. We do what’s called we stated it’s for hydrocarbon viscosity, and the reason for that is because hydrocarbons have a very known, viscosity profile across all different pressures and and temperatures. And so we can we can verify on water and ensure that the meter is going to react properly, and and maintain the accuracy that we stated it’s going to have. And, again, this is a monitoring point. It’s not necessarily a calibrated point. It is plus or minus 10% accuracy, which isn’t very high, but it’s it’s enough to where you can start seeing when you have the difference between a very heavy crude oil and water or a very light crude oil or, like, light hydrocarbon. And the repeatability is ultimately where where the the use case comes in. So this is one of the highlights that I wanted to to point out because I think not only on the monitoring side, it gives us more values, it gives us more information on on what’s happening inside the meter, without us having to open up the meter, and and or open up the the pipe and and look at it. So a couple of applications, typically you’re gonna see them both, in all parts of oil and gas, which is upstream, midstream, and downstream, all the way into, refining products. A lot of these applications, in in midstream, especially in pipelines, is going to be the addition of some sort of drag reducing agent. So we can understand as adding that as we start adding that drag reducing agent into pipelines, how much effect is it actually having? Are we changing the properties enough of the product, or is it, are we not changing it? Are we changing it too much? It gives us, more of a, a qualitative understanding of the product that’s going through the meter. So and, you know, I’d I’d mentioned earlier, you know, we do, a lot of industries, but, you know, I guess the two completely opposite industries would be something like oil and gas and, life sciences or pharmaceutical, And that kind of plays into this transition here into our, ProMASS U. This is our, is a relatively new product, that we’ve had out for less than a year at this point. But our ProMASS U is our single use Coriolis technology. In a lot of pharmaceutical applications, there’s a lot of challenges in terms of cleaning, in terms of making sure that there’s no risk of cross contamination. And the biggest thing with that is, the introduction of single use production. So taking cells, biology, all the way through to a, a marketed medicine or a product, but using all single use products. And that saves on risk for cross contamination, especially in large factories. And, it also actually does save some money because of the amount of chemicals and and cleaning that has to go on in a lot of these pharmaceutical companies. A single use technology kinda fits the need in in that industry very, very well. Shawn Tierney (Host): So what I’m looking at here is it looks like a a lab tabletop type device Yep. And the the u, right, the the the pipes is replaceable. So Yes. It looks like a cartridge where you would, like, you know, turn a lever. You could let’s say you ran product one and you ran that for a while and then you’re done. You would turn this lever, release the cartridge, pull it out, and those pipes don’t have to be cleaned. They can be disposed of. And now you put in your new one, and you can run a different product. And we all know, like, a few years ago, we all heard the horror stories of a pharmaceutical that makes two different batches of medicine, and it was like nightmares. Thank god. That never get out into the real world because only only god knows what would happen. So that’s that’s I like you can’t we can’t exclude that type of cross contamination just can’t happen in Yeah. The twenty first cent in the twenty first century. So but this this is so interesting. Is this c is this something that would be in a I’m just looking at such a nice looking desktop device. Would this be something that was only used in a lab or could it actually be used in a production line? Lauton Rushford (E+H): Yeah. So there’s there’s two versions. Okay. There is a tabletop, which is what you can kinda see on the screen where we have this chassis built around, the the there’s really three components in this. There’s a a transmitter that’s kind of sitting at the top there. There is a base unit, which is where the sensor goes into, that has all the electronics, and then you have your disposable sensor. So the sensor is where all your fluid is gonna be flowing through. Shawn Tierney (Host): Mhmm. Lauton Rushford (E+H): The base unit is doing all of the, manipulation on the tubes themselves. So we talked about how a Coriolis meter works or oscillating those tubes. The base unit is actually doing that, and then the transmitter is taking all of that raw data, understanding it all jumbled up, and giving it out a flow rate, a very accurate flow rate. And there’s two different versions of this. There is a test desktop version and a panel mount version. So the panel mount version would be, you know, in a skid of some sort. Mhmm. That would be permanent, but then the the single use cartridge would be pulled out, disposed of, and then a a new one would be replaced there. And and that’s kind of kind of what we’re gonna get to too in a little bit once we start seeing some of the challenges in this industry. So this industry really is is it’s not new, but it is in terms of process instrumentation. There’s not a lot of manufacturers out there who who have single use flow technologies. So there’s a challenge from our perspective as as the the manufacturer to try and meet all of the requirements of the industry, while providing a robust, accurate, reliable sensor for these applications. And so that’s where our r and d kind of, hit a hit a snag at at one point almost because they’re they’re so used to making robust products that last ten, twenty, thirty years in process. Now we have to look at a product that we want to also do all of those things, but also be disposed of. And so there’s there’s some challenges there. Similarly, there’s a challenge of of calibration in a lot of pharmaceutical plants because certain products require calibration before they’re even installed. Certain products require calibration before they’re installed and while on-site. And then, if there’s ever a replacement that goes in, there’s an additional calibration that might have to happen. And so what we wanted to do was take all of those constraints, all of those challenges, and try and check the boxes of all of them. And I think that’s kinda where our single use landed. There are still some, you know, some certain applications that are challenged, but they’re always gonna be a challenge, until there’s some innovation that comes out that that truly meets that need. But, I guess, in general, really, if if you look at a high level, it’s a half a percent accurate device. We have four different sizes of of sensors that can go into the same base unit. We have an eighth inch, a quarter inch, a half inch, and a one inch sensor that will go into this base unit. They all fit into the same base unit. So as we talked about it with an example, using product A, maybe you’re only flowing at 10 liters per minute, but then product b, you’re flowing at 75 liters per minute. Well, technically, those should probably be two different flow meters, but we can just change the different cartridges out, and and there’s no risk of of contamination, and there’s no need to change anything other than the sensor itself. It is gamma sterilizable, especially in pharmaceutical. That’s really important to make sure that there’s no contamination at all from anything in production, from any anybody’s hands getting on it or anything like that. We don’t do it as a manufacturer. We would kind of rely on our OEMs, on our, tube set manufacturers to actually put these skids together, and part of that package would be to gamma sterilize all of the fittings, all of the tubing, as well as as well as the the flow sensors. And then we also talked about the different the different designs that we have. It is stainless steel tubes, which is different, and it’s polycarbonate flow splitter. So if you see that purple part on the screen, where our tubing would come into, that is a plastic or a polycarbonate product. And then the tubes themselves where we’re actually performing the measurements is a stainless steel, three sixteen l, material, which is different because at when you think about single use, you think about plastic. You think about, bags that are plastic, bioreactors that are plastic, because they’re easy to throw away and they they’re inexpensive. But we felt like in order to meet all of those challenges and all of those, constraints in terms of, current, sensor designs, we felt like the most robust way to do that would be to use stainless steel. And we have a long history of of manufacturing stainless steel devices, and so this is just, another way that we could, show our our expertise in in in products and in especially in Coriolis meters. So there are, as I mentioned, three components. You have your base unit or your single, single use disposable sensor. Down at the bottom there, you have your base unit, which is again where all your electronics are, and then you have your, and then you have your transmitter. And there’s a cable going from the the transmitter to the the base unit. There’s a couple of things I want to highlight on the inside of what the meter is and how it what it looks like. The first thing and probably the most important is that barcode scanner. So every single one of these disposable flow tubes gets calibrated at our factory and then gets imprinted a QR code on the inside of the flow meter. And that QR code, that two d barcode scanner actually scans that information. So it can it can accurately pull in the calibration information. It can pull in the serial number of the tubes. It can pull in the line size of the tubes. It can pull in a lot of information related to those tubes. And then it can relay that back to the transmitter, and the transmitter can check to make sure everything seems functional. And that kind of falls into where our heartbeat technology, conversation may come in in in just a little bit. And then again, all the electronics are our sensor electronics boards, our, ISCM or our sensor electronics module, all is based inside that base unit, inside this very large not not very large, but a a very heavy bodied base unit to ensure stability, across the board. And so here’s an example of what that QR code kinda looks like on the on the backside of that that flow tube, and then another, look into kind of what the the the inside of the base unit looks like. You see coil inlet one, coil inlet two, or coil outlet two. Similarly to kind of what we talked about before, we really care about what’s hap what’s going on in between those tubes, in between those those two coils. And so we’re magnetically oscillating the, the Coriolis flow tubes inside at that back piece, that back, what is that? It’s like a gray type ceramic piece in the back, and that’s ultimately giving us giving us that oscillation that we’re looking for. And then our inlet and outlet, pickup coils are also magnetically coupled to to the sensors, and, we can detect very small changes in those at that oscillations those oscillations. So very very cool, very innovative. It’s a product that we’ve had out for a while in, a while, less than less than a year, but long enough. And there’s been a lot of interest in in the pharmaceutical space, especially as people are trying to save costs, go closer to maybe a personalized medicine approach, where there’s gonna be smaller, amounts of product going through, more expensive amount of product going through. Accuracy is gonna be the most important there. And so this is where, we kinda talk about a little bit more about how to maintain that data trail, that automated data trail from the cal the calibration in the factory all the way into production. And so in this case, what we what we’re looking at is, here’s the process of what would happen in in in a in a system. We would calibrate the tubes at our factory. The tubes would go to a tube set manufacturer. The tube set manufacturer puts all of these pieces together. They double bag them in a class seven ISO, ISO class seven environment. Super clean area, no risk of contamination there. And then just to be even more safe, they’re going to gamma sterilize it there. Then they’re going to bring it on-site where they have their skid created, and they’re gonna plug everything in. And then once they plug everything in and turn the entire skid on, they’re gonna, they’re gonna notice that on the flow meter, it says, hey, we’re doing a function check right now. What does that mean? That’s ultimately what we call heartbeat technology, and that’s doing some advanced diagnostics behind the scenes. And it’s checking information like electronics in the bit in the base unit. It’s checking, tubes, making sure the tubes are aligned and weren’t damaged in shipping, and ensuring that the the factory calibration is still valid on the current device. So all of that is happening kind of behind the scenes before you, even start running product through it, to ensure that we are fully CGMP or, current good manufacturing practice and operation, on a production side. And that kind of maybe leans leads a little bit into, another product that we’ve recently released, which is our Anderson Hauser ProMASS k 10. It’s the first Coriolis meter, in the world that has IO Link as an output. And now IO Link, I I think it’s really important to start with a really good basis about what IO Link is, and IO Link is something I call it the three wire digital communication, but it it’s not a 100% accurate. So we’ll maybe dive into that a little bit and talk about what IO Link can do, and how it is, is being accepted in industries, specifically in farms, in in food and beverage and pharmaceutical industries. As a general rule of thumb, most large smart factories are using Ethernet based protocols. So that means that their their the devices that they have, the control system that they have is all digital, which means you can get a lot more data and get a lot of data. You can get so much data you have no idea what to do with. There’s also, these Ethernet switches that are typically either remote Ethernet switches or switches that are out in the plant that, that are pulling in a lot of this data and then sending it up to whether it’s their asset management system or a control system, and ultimately can give us the most amount of information about the health of the device, any sort of multivariable, values that we have coming out of the device. And then similarly, on the op on the right side here of this screen, you see an IO Link system. IO Link also does a very similar thing where you have a remote, what’s called an IO Link master. It’s connected to a flow meter or connected to a level switch or connected to, a temperature probe, and it pulls all that information in, and then it outputs that information back to their control system. And so historically, we’ve had a lot of Ethernet four wire devices, whether that’s Ethernet IP, PROFINET, Modbus, any sort of digital heart as a as an option as well. That’s historically been where our Ethernet four wire and two wire devices come from. Now IO Link hasn’t really been a focus for us, but because of our our diversity in different industries, we’ve had to look at IO Link as a feasible, cost efficient choice for basic process needs in under in in flow meters, in pressure transmitters, in a lot of devices, and a lot of a lot of different applications. And so there’s some benefits and pros and cons to both. Ethernet, you have a lot of process devices versus simple simple measurement points. The, the IO Link, you have a specific range in terms of distances. That’s only about 60 feet, which means it’s really, really good for those skid solutions, that are put out in into many, many factories and especially especially in food and beverage. The IO Link masters are really where the integration happens. And then the data that’s recorded and aggregated is happening inside that IO Link master where typically on a, Ethernet based system, you all have full transparency from, device level all the way up to your your control system, DCS system, throughout and anywhere throughout that system as well. There is uses for both even in the same plants. There’s uses for both in in similar applications, but I I think one of the benefits is being the first, Coriolis manufacturer to have a IO Link device. What does that mean? Really, what it means is we can get some very good data, not all the data, but in many cases, we don’t need all of the data, and we can be super accurate, extremely fast in terms of data data transmission, and, make things a little easier in terms of of integration and installation of the devices. So typically what a a system or a subsystem might look like with IO Link, you have your IO Link master, that’s where power is is brought to, and it’s also where our connection to that overarching enterprise system or DCS system is. So that IO Link master is a must. You have to have that. You also have to have a flow meter that is or any device that is capable of outputting in an IO Link protocol, in an IO Link communication method. And then there’s a specific three wire cable that goes from the device to the master. And there this is the often overlooked thing, but it’s an IODD. Essentially what that means is it’s an IO Link device driver. So that device driver is gonna tell the IO link master what and how is this device sending information to me. So it’s almost like a little roadmap for the IO Link master to understand what’s happening on the on the base the base level of, of that IO Link device. Ultimately, these are the four things to have that you have to have for, basic subsystem components. And then, as you start integrating it to into an overarching system, there’s a little bit more that would be needed as well, but this will at least get you started, and understanding kind of why there’s IO Link masters, and why there’s IO Link protocols and technology in the first place. So again, this is our Coriolis k 10, with our IO Link master. It’s a line size three eighths of an inch all the way up to three inch. It also has what we call heartbeat technology. It has, three a. It has all of our, approvals for hygienic applications, for food and beverage applications, for pharmaceutical applications as well, and gives us a little bit more flexibility in terms of what we can offer our customers that will meet the need of where they’re at, but also prepare them for for future, expansions and, and and large scale DCS turnarounds and things like that. So, there is a couple of things here, mass flow as a standard with density, temperature, and you get a standard totalizer one as an output. There is, again, food contact materials, eHedge three a, all hygienic process connections as well as standard process connections, available with this device. And then one other key factor here is when we’re in actually interacting with this device, there’s a couple of ways we can interact with it. We can, of course, use a a touch screen. We can push the device and and be right in front of it. There’s also a method for using a free app that we have on on the Android store and the Apple Apple Store. That’s called SmartBlue. That’s available for a lot of different devices, but it is using a Bluetooth technology to, tap into the device and configure, everything. And then the other option is using a, a device manager, with a CDI port that’s built inside the transmitter as well. So all different ways to to interact with the same device, even, interacting with it using IO Link is possible as well. So a lot of different functionalities, a lot of different, options, so we can meet the needs where meet the customers where their needs are, and then also where their they wanna get get to. So that kind of takes us into what heartbeat technology is. And we actually we talk about heartbeat technology as a story because I think if we start talking about what it is before we talk about the story, it’s, it’s it’s it’s hard to to wrap your head around. There’s a lot going into it. And part of that that discussion really starts with a a marketing phrase, which is called taking the pulse of your measurement. And what that really does is is it’s trying to understand how the device is operating currently, and how the device may be operating in the future based on current conditions. And so all all of that is is started with what our customers expect out of a flow meter, expect out of a pressure transmitter, expect out of a pH probe. All of our customers’ needs and our users’ needs are expanding. So not only do they need excellent measurement performance from a device, they also need a reliable device. I I need to know when something’s going wrong. They also wanna be available. If the device itself isn’t always available, they can’t trust it. We want our customers to not only trust our device, but trust the measurement performance that they’re getting out of the device. And they also want it easy to easy to use. As we’ve seen in a lot of industries, the, the operations teams, the operators that are on on the plant floor are getting less and less, and maybe they’re moving more towards engineering. But there are a lot of plants that are running extremely lean. And so running lean means they have to run efficiently and they have to run effectively. And if our devices are not easy to use and easy to understand, we’re we’re kind of failing at at that point. So we also wanna make sure our devices are safe. We wanna make sure our devices are predictive, and we wanna make sure our devices potentially can be connected in the future. And so all of those together is now now we’ve got a difficult puzzle we’ve gotta try and solve, with any one of our measurement devices. And that’s where we think kinda heartbeat technology meets a lot of those needs and bridges the gap between, the excellent measurement performance and and all of these, needs that we have. So we split heartbeat technology into kind of three categories. We have diagnostics, which is, current, current status, current device diagnostics, advanced diagnostics. That’s the basis of everything. So if we don’t have a good basis of diagnostics, we can’t do verification. We can’t do monitoring. We can’t provide in, improved process insights, very effectively if we don’t have a good base unit. So that happens from that happens from the the design of our devices all the way down to the raw components that go into all of the devices as well. And then verification is kind of a what’s happening to my device right now, and can you give me a PDF printout of what that looks like. So that’s that’s part of the verification. And then again, monitoring how we look at certain values over time trended over time, so we can start understanding, predictively when certain process conditions or process upsets may happen or could happen, and how will they affect our measurements. So all of that together is really bridged on the diagnostic coverage. It’s based around how we can detect our, any alarms, alerts, failures, things that happen inside the device that weren’t expected. All of that needs to be, really, really important. And so our IO modules, our sensor electronic modules, our sensor, inlet and outlet pickup coils, and our divi our ex the entire excitation system that’s happening inside of a of a Coriolis meter, all are really, really important to understand the health of the device. If we can understand the health of individual components of the device, we can try and better understand the health of the entire device as a whole. Kind of the sum of, sum of equal parts or the sum of parts is is greater than the than the sum of the the system. So, that’s ultimately what we’re trying to do here. And what that means is that this value, the heartbeat sensor integrity parameter is always generated and can be used as a direct value for, understanding process related concerns as well as meter concerns. So in a similar way, we talked about, oscillation modes with our PROMAS Q, with our PROMAS I, and other flow meters as well. The frequency or the oscillation frequency that we’re actually doing for this HBSI value is a fixed diff distance from that frequency. And so at any one time, we’re we’re oscillating these tubes at one, two, almost, three every, three different frequencies every time. And so the part of this this parameter is ultimately giving us a little bit more information related to the health of the sensors, related to, even the health of the process as well. And we’ll talk about a couple of use cases on on how that, and what that means, and and can ultimately mean for you. So as a general rule of thumb, when we calibrate and design a new sensor, our HBSI value, is 0% at reference conditions, and that may fluctuate depending on if you’re operating at reference conditions or not. But right around zero, it could be negative point one to positive point one, percent, but there’s no no cause kind of for concern there. We do have kind of a stated bandwidth in which we expect the flow meter to operate well within its its factory calibration and well within its specification. But if that value shows very, very low, or values, like, right around zero as a reference condition, your HBSI value is related directly to sensor components that aren’t affected. So if our exciter current, if our pickup coils, if our, sensor tubes are not damaged, likely that HBSI value is going to remain at zero or right around zero. Now when we do have something like a wear mechanism, something like corrosion or erosion or abrasion inside the tubes, ultimately, there’s things that are going to be affected by that. Now how do we actually detect that? Well, that’s where using this HBSI value, we can actually understand individual components of the the flow meter, individual, components like the sensor tubes. For example, if we were to have a corrosion instance, your wall thickness of the tubes would change. And so what what would happen there is as we start oscillating these tubes, you would start to see that value increase because your tubes are moving moving more and more and more because we’re oscillating at the same frequency or at the at the same frequency, but the tubes is not our tubes are not as heavy. Right? So, that’s where that that HBSI value can give us information related to, kind of the health of all of our devices or all of our our components within the device. So there’s multiple ways to observe that HBSI value, and this is where trending comes into play, looking at something and trying to be predictive and preventative, in the long term. There’s no process interruption. This this entire thing happens. This entire, HBSI value is generated, automatically by the device itself. It remained the measurement remains completely available, continuously available, and it happens in situ behind the scenes, if you will, of a of your measurement. And then you’re gonna improve efficiency, obviously, and and reduce risk if you understand what’s happening and what’s going on inside the flow meter without you actually visually seeing what’s happening to the device. So, all of that to say, there’s a lot of ways to observe it, but there is also important ways, that we can use it. So, yes, knowing that the HVSI value is zero is just that’s great. That’s awesome. But what does that ultimately mean? And here’s a couple of examples. Here’s a couple of use cases. So we’ve had an application, in the past where, it was an abrasive fine slurry. And so anytime you have abrasive fine slurries, you have to be extra cautious of using bent tubes, and also the velocities in which you’re flowing those those those processes through there. So the initial one, they had was a dual bent tube that failed six months in the service, and they replaced it with a single straight tube. So they expected to see some abrasion, but because of the design of the flow meter, that HBSI parameter was taken over time, and it’s been installed for for four years now and shows a relatively flat line behavior for the the HBSI value, meaning there’s no wear mechanism going on inside that device, be because of the process. So that’s a that’s a use case there. Another use case that that we talk about a lot is is the presence of abrasion in general. We know that in some applications, there is going to be abrasion. And that’s on us as the manufacturer, that’s also on, the customer to understand what their levels and limits are, and are capable of handling. And if they don’t know, that’s that’s where we we should probably step back and say, hey, let’s let’s talk about this as a as a at a high level. What happens when something goes wrong? Do you just automatically remove the device? Is it are you down in terms of, not being able to produce properly? Things like that. And that’s where in this case we used, kind of predictive maintenance every ten, twelve, fifteen, eighteen months. We know we have to replace this device because of the abrasion, or we have to decrease our velocity, through the meter. So either way, that’s ultimately this use case and showing showing that there is a wear mechanism happening, and we need to understand at what point do we need to start replacing these devices. And lastly, here’s one that was an unexpected wear mechanism. So customer used a Coriolis flow meter, and for five days, everything was great. No worries. Everything was totally fine. Customer didn’t expect anything to be wrong, which is exactly what was shown. And then once they did a cleaning cycle with a new product a new cleaning product, they noticed that this value increased. And so over time, I mean, think about twenty five days, you’re increasing your HBSI value because you’re performing your regular scheduled cleaning. Well, that wasn’t understood, and that wasn’t, that didn’t the the customer didn’t know that was going to affect things. We didn’t know that was going to affect things, but this ultimately shined light on, here’s what’s happening. Now can we change cleaners, or can we use a material that’s more compatible with that cleaner, or can we just live with the the, the risk that the the values will last long enough for us to get really, really good good data, and then we can, and look at replacing it, things like that. So this was another, application where we weren’t expecting to see any sort of drift, but we did because of, the the wear mechanism that that wasn’t, very well known or or present at at the time. So, ultimately, I think, you know, using, something like heartbeat technology as a, a confidence boots booster in your measurement is is really the the key there. Because I think the more that we can increase confidence in our measurements, the more that our customers, will continue to want to to work with us and collaborate with us on on applications and and talk, about, different, industry applications and things like that. As as the working for a manufacturer is currently my my first my first job, I think I think, out of college, I think there’s a there’s a really cool benefit of of a privately owned company that continues to invest in research and development for the products that we have. And, I think that, you know, Anderson Hauser has has done a great job of, showing some innovations that we can within our Coriolis flow flow meter technologies. That’s all I got. Shawn Tierney (Host): Well, I thought that was very interesting, especially the HBSI, how you guys have in included that in your product so you can see that everything’s good, or if something is starting to go out of out of, you know, out of I don’t wanna say out of whack. You know, something’s starting to go out of alignment, you know, with Yeah. What you were expecting. And that example of cleaning, you know, nobody would have thought, you know, this, you know, this product is designed to run this fluid through it, but the cleaner, they’ll finding out that the cleaner was the problem. That’s priceless. Right? That’s priceless. And you can you like you said, there’s different options you can take to address that issue, but now that you know what the problem is. If you didn’t know there was a problem, then your values would be off over time, and that wouldn’t be good at all. Right. So Right. Just such an interesting topic to talk through. And I I appreciate you not only to take us through your products, but also taking us through some of the technologies that are built in the products and that make them work. And I you know, there’s a lot there between the, field bus, the PROFINET, and the Ethernet IP on your really high end, high accuracy, you know, type of installations versus maybe a smaller installation where you can use IO Link because it’s slower cost. We just had the IO Link folks on the podcast. If you guys missed that, just, check back, a podcast or two ago. We had the IO link guys on talking about what they do and how they do it, and I think you summarized it very well in this presentation. And so I think that makes a lot of people happy because in many cases, that’s a lower cost. Yeah. I mean, you’re not gonna get the same performance as you’re gonna get over Ethernet, but you’re it’s a lower cost, and it’s, you know, maybe enough information for your application. So it’s good to see that option there, especially for those skid manufacturers who can utilize those products. You know, with that, I I don’t have any other questions. Was there anything else you wanted to say before we close out the show? Lauton Rushford (E+H): No. All I have to say is thank you. I appreciate the the time and the the the platform. I think this is, awesome, and thank you for asking all the questions you did. I think there was a lot of a lot of really good information that you mentioned, as well there too. So, thank you. That’s all I have to say. Shawn Tierney (Host): Well, Lon, thank you for coming on. I, I just like the first time we had Anderson Hauser on, it was just really just so intellectually interesting. So it’s our pleasure to have you on, and we really appreciate you guys. Lauton Rushford (E+H): Thank you. Appreciate it. Shawn Tierney (Host): Well, I hope you enjoyed that episode, and I wanna thank Lawton for for coming on the show, not only to bring us up to speed on Coriolis flow meters, but also answering my questions because I know I interrupted there, especially at the beginning with a lot of questions. So really appreciate him, taking my questions and also bringing us up to speed on the technology. Now Now I also wanna thank E and H for sponsoring this episode so I could bring it to you ad free on all platforms. I don’t like ads, but, you know, you gotta pay the bills. And when a vendor comes in and they sponsor the show, it really underwrites our cost to edit it and publish it. So I’m super appreciative to them and to all our sponsors who do that. And please let them know if you see E and H anywhere out there, if you’re talking to one of their reps or you’re talking to, somebody from E and H, please let them know how much I appreciate and maybe you appreciate that they sponsored this episode. I also wanna mention that you may not know this, but I brought my other podcast back, the automation news podcast. I renamed the automation tech talk. And anytime I have an episode that is, one of my shorter episodes that I think will do good on audio, be a good listen. Right? I am publishing it on that automation tech talk podcast. And on this podcast, you probably notice every once in a while, I’m releasing an episode of the automation show. Some episodes of the automation show, there’s so much hands on that I don’t think they’d make a good audio addition, but some of them are like presentations and discussions. And I think those would make a good episode of the automation podcast. So I’m releasing them on this podcast channel, but I’m keeping the name, the automation show. So you know, hey. This is, originally was a video that was turned into a podcast. So give me feedback. If you don’t like those, I’ll stop doing it. But I thought because, some weeks we can’t always bring you a new episode, we may have an episode of automation show that I think would make a good listen. So I wanted to bring those to you on this platform as well. And, again, I always love your feedback, and I wanna thank everybody who’s given a five stars or thumbs up. You guys are great. I you know, last time I checked on it, you had so many people, had given us five stars. And that you know, that’s really how we find new vendors come out, like E and H and other vendors. Right? They specifically said you guys were such had such great feedback on the previous podcast that they wanted to come back on. So please take a moment. I know a lot of you listen while you’re driving. But when you get home or get to some place where you can look at your phone, please give us a thumbs up or a five star rating because that really helps us grow the audience and find new vendors to come on the show. And with that, I’m gonna end the show right there. I wanna wish you all good health and happiness. And until next time, my friends, peace. Until next time, Peace ✌️  If you enjoyed this content, please give it a Like, and consider Sharing a link to it as that is the best way for us to grow our audience, which in turn allows us to produce more content

What if process intensification could transform your bioprocessing economics without the complexity most engineers fear? Getting 3x productivity gains and 30-150% titer increases once seemed reserved for Big Pharma's endless R&D budgets, but a strategic approach to technology selection is making these results achievable for companies of any size.In this episode, David Brühlmann speaks with Andreas Castan, a bioprocess veteran with over 25 years of industry experience who provides leadership and support to Cytiva's bioprocess business. Andreas brings deep expertise from directing upstream development at Swedish Orphan Biovitrum and extensive work in expression systems, process development, scale-up, and cGMP manufacturing across multiple therapeutic modalities.Why tune in? Here's your process engineer's roadmap:Process Intensification Economics Decoded: Andreas reveals the cost-benefit reality behind continuous vs fed-batch manufacturing, including real process economic modeling data showing why the differences aren't as dramatic as you'd expect and what factors actually drive your business case.Low-Hanging Fruit That Delivers: Skip the overhyped AI solutions. Andreas shares the strategic fundamentals that work: high-producing cell line development, N-1 perfusion for rapid productivity gains, and smart bioreactor turndown strategies that eliminate process steps without adding complexity.Decision Framework for Technology Selection: Learn when continuous processing makes economic sense (and when it doesn't), how media costs impact your COGS analysis, and why understanding your bottlenecks, not following industry trends, should drive your intensification strategy.Industry Insider Strategies: Get the inside track on what AstraZeneca, Sanofi, Merck, Lonza, and Takeda are actually implementing, plus Andreas's perspective on why human expertise and mechanistic insights still outweigh AI in real-world process decisions.Ready to make smarter technology investments and achieve measurable productivity gains? This isn't theory. It's a practical guide to process intensification economics that you can apply whether you're preparing for Phase I or scaling for commercial manufacturing.Connect with Andreas Castan:LinkedIn: www.linkedin.com/in/andreas-castan-91570b1Cytiva landing page: Process intensificationOnline tool: Process intensifierNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call

Hey listeners! Got plans for October 10th and 11th? Well, clear your calendars, because the FACTS About Fertility Virtual Conference is coming in hot and you won't want to miss it. Listen in today to Dr. Marguerite Duane and all the incredible work she is doing with FACTS, but also she is now the Director of the first ever Fertility Awareness Based Medical program in a medical school, Duquesne University! We're talking TWO days of inspiring talks, real connection, and expert insight—all from the comfort of your favorite sweatpants.

As the seasons change, our eating habits often shift — and this is also the time of year when many of us start thinking about how to optimise our immune response and maintain resilience.That's why, for September and October only, Conella is offering an exclusive 30% discount across our entire branded range. This includes trusted favourites such as Maxi-Immune+, Maxi-D & K, Vitamin D3 Peppermint Mouth Spray, and Maxi-Vit C, along with other essentials like Maxi-Mag+ and Mega-Cultri-Max. And of course, every order includes free delivery across the UK mainland.But Conella isn't just another supplement brand. We are pioneers of Electromagnetic™ Nutrition — a science-led approach that combines naturopathic wisdom with bioenergy insights to optimise your body's cellular energy, or ATP production.That means:Formulas designed to support cellular rehydration and mitochondrial efficiency.Only the highest-purity, non-GMO raw materials — all fully UK-compliant and rigorously researched.A commitment to traceable sourcing, with products manufactured in cGMP-certified facilities that meet ISO 9001:2015 and NSF GMP standards.And most of our products are Vegan Society-registered and free from unnecessary additives.We know the supplement industry faces real challenges — with studies showing that many products don't always contain what their labels claim. At Conella, we address this through rigorous testing, transparent sourcing, and full UK regulatory compliance, so you can always trust what's in the bottle.And new for this autumn — we're also offering a free nutritional advice call by Zoom or phone. There's no purchase necessary — it's our way of giving you personalised support, whether you'd like seasonal health tips, help choosing the right supplements, or guidance for your family's wellbeing.So, are you ready to begin? This autumn, re-ignite your wellness journey with Conella and enjoy:30% off all Conella branded products, valid September and October with voucher code SEPT30.Free UK mainland postage.And a free, no-obligation nutritional advice call.

In this conversation, Dr. Shawn Tassone and Monica discuss the complexities of the fertility journey, emphasizing the importance of holistic approaches and emotional well-being. They explore the challenges women face in trusting their intuition amidst overwhelming information and medical advice. Monica shares her insights on the need for women to slow down, embrace their innate fertility, and prioritize their health and emotional state before pursuing treatments like IVF. The discussion highlights the significance of conscious parenting and the necessity for women to reclaim their power in their fertility journeys. Episode Highlights: Why women often struggle with trusting their intuition in fertility How the fertility journey is not a one-size-fits-all process Why type A personalities may face additional challenges in fertility IVF success rates are not guaranteed and can be influenced by stress Why holistic health approaches are essential for improving fertility How emotional well-being plays a crucial role in fertility success Why women need to prioritize self-care and slow down during their fertility journey Why trusting oneself is key to navigating fertility treatments Why pregnancy does not equate to overall health Reasons conscious parenting is vital for future generations Episode Resources: Dr. Shawn Tassone's Practice | www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.    

In this episode, Dr. Shawn Tassone discusses the fundamentals of hormonal health, focusing on the roles of estrogen, progesterone, testosterone, DHEA, and thyroid hormones. He emphasizes the importance of understanding these hormones, their effects, and the misconceptions surrounding them. The conversation also touches on the significance of finding the right hormonal balance and the potential risks associated with various hormone therapies. Episode Highlights: The recent flooding in Texas serves as a reminder of community support Understanding the basics of hormones is crucial for health The three types of estrogen The most effective form of estrogen Why you should avoid using estriol face creams Fiber intake and estrogen elimination Estradiol for women with a history of breast cancer Progesterone's role for women Why testosterone should not be overlooked in women's health How DHEA can be beneficial for women Episode Resources: Dr. Shawn Tassone's Practice | www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.  

In this conversation, Dr. Shawn Tassone discusses the importance of holistic health and hormone balance, introducing his SHINES protocol and the Holistic Health Bundle. He emphasizes the value of the resources included in the bundle, shares testimonials from satisfied customers, and explores the various courses and content available. Dr. Tassone encourages listeners to take advantage of this opportunity to enhance their health and well-being. Episode Highlights: The SHINES protocol integrates spiritual practice with health. The Holistic Health Bundle offers over $5,000 worth of resources. Testimonials highlight the transformative impact of the bundle. Holistic living includes natural beauty and non-toxic home care. Herbal remedies and detox solutions are key components. The bundle includes courses on children's health and wellness. Dr. Tassone's course on hormonal archetypes is a highlight. Community feedback shows high satisfaction with the bundle. Investing in health resources can lead to significant benefits. Dr. Tassone is available for virtual consultations. Episode Resources: Holistic Health Bundle - Available until July 16th @ 11:59PM EST Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.

In this episode of the Root Cause Medicine Podcast, Dr. Kate Kresge sits down with Dr. Eric Viegas, a naturopathic doctor and Fullscript's Medical Product Manager, to pull back the curtain on the world of supplement quality and safety. From raw ingredient sourcing to manufacturing audits, Dr. Viegas explains what CGMP really means, how Fullscript ensures product integrity, and why certifications like NSF and third-party testing matter. You'll learn how to evaluate your supplements for quality, what common industry terms really mean (or don't), and what to avoid—like potentially dangerous sports nutrition products and under-tested trendy gummies. Whether you're a clinician or a supplement-savvy consumer, this episode offers practical insights to help you navigate the supplement landscape with confidence. You'll here them discuss: - What CGMP certification actually means—and why it matters - The hidden dangers of poor manufacturing practices and counterfeit products - Why Fullscript's catalog is CGMP-certified across all 375+ brands - How and why supplements like turmeric are tested for purity, potency, and contamination - The surprising problems with gummies and “pharmaceutical grade” claims - Which third-party certifications actually mean something (and which don't) - Why the supplement industry is regulated—but not in the way most people assume - How Fullscript handles recalls, audits, and adverse event reports - What every provider and consumer should know before recommending or taking a supplement

Menopause isn't a medical condition requiring endurance—it's a physiological transition that responds to intervention. While the diagnostic criteria demand 12 consecutive months of amenorrhea, waiting a full year to address debilitating symptoms defies clinical logic. When patients present with vasomotor symptoms, mood dysregulation, and menstrual irregularities, laboratory evaluation can provide diagnostic clarity before the arbitrary 12-month mark. The key is recognizing that symptom management doesn't require a completed diagnostic checklist. This episode dissects the diagnostic approach to menopause, examines the cultural mythology that keeps women suffering unnecessarily, and provides evidence-based perspectives on hormone replacement therapy. We'll explore the actual risk-benefit profile of HRT, the cardiovascular and skeletal implications of hormone deficiency, and why decades of misinterpreted data have created widespread HRT phobia. Because apparently, we needed a Women's Health Initiative study to convince everyone that horse urine hormones aren't ideal for human women. Episode Highlights: Clinical definitions and diagnostic nuances of perimenopause versus menopause Laboratory markers and symptom patterns that inform menopause diagnosis The overlooked significance of testosterone assessment in menopausal women How societal expectations perpetuate the "suffer in silence" mentality Deconstructing the HRT fear-mongering that followed flawed research interpretations Evidence-based rebuttal to the estradiol-breast cancer causation myth Comprehensive approach to symptom assessment and therapeutic options Risk-benefit analysis of bioidentical estradiol and progesterone therapy Comparative evaluation of progesterone and estrogen delivery methods Clinical consequences of testosterone deficiency in women Pre-treatment evaluation and contraindications for HRT initiation Role of genetic testing in personalizing hormone replacement protocols Distinguishing natural menopause from surgical menopause management strategies Episode Resources: Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.

What if we told you that your menstrual cycle isn't a weakness to overcome—but a superpower to embrace? In this bold and empowering episode of The Hormone Genius Podcast, Jamie and Teresa are joined by Jillian Bosak, women's health and performance coach, founder of Jillian B. Well, and a passionate advocate for redefining what it means to be a thriving, high-performing woman—in sync with your cycle. Jillian brings to light the often-overlooked truth: most women are being trained, coached, and supported as if they were men. With only 6% of sports science research conducted exclusively on women, the female experience in fitness, performance, and health is being sidelined. But not anymore. Together, we dive into: Why birth control being labeled as “women's healthcare” is a disservice—and what women actually need How tracking your cycle gives you clarity, power, and performance insights What athletes (from everyday movers to pros) should look for when syncing training with their cycle How your hormones are not the problem—they're your secret weapon Why the female body is not fragile, and how to stop suppressing what makes it uniquely strong Jillian's message is clear: You are not broken. You are brilliantly designed. And when you understand your hormones, you unlock a level of strength and confidence that can radically shift your life and training—for good. This episode is for women, coaches, athletes, and anyone who wants to stop fighting their body and start working with it. Whether you're an everyday athlete or pushing elite-level performance, your hormones matter. And it's time the world recognized that.

In this episode, Dr. Shawn Tassone examines a paradigm-shifting study from the Journal of the North American Menopause Society that demolishes decades of unfounded hysteria surrounding hormone replacement therapy for women over 65. The research reveals that HRT—specifically estrogen therapy—administered beyond age 65 correlates with significant risk reductions across multiple disease categories: mortality, breast cancer, lung cancer, colorectal cancer, congestive heart failure, venous thromboembolism, atrial fibrillation, myocardial infarction, and dementia. The findings underscore the critical importance of precision medicine approaches utilizing individualized protocols, lower dosing strategies, and non-oral delivery methods for optimal clinical outcomes. Episode Highlights The NAMS study that's rewriting the hormone therapy playbook for women over 65 Quantifiable risk reductions across nine major disease categories, including the holy grail of mortality reduction Why the data on breast cancer, lung cancer, and colorectal cancer risk reduction should make us question everything we thought we knew The cardiovascular benefits that contradict decades of clinical paranoia: reduced congestive heart failure, venous thromboembolism, atrial fibrillation, and heart attacks Dementia risk reduction—because apparently estrogen is neuroprotective, not neurotoxic The vindication of individualized hormone therapy protocols using lower doses and transdermal delivery Estrogen monotherapy combined with progesterone: the life-extending intervention hiding in plain sight How this research obliterates the arbitrary age-based cutoffs that have dominated clinical practice Why your patients over 65 deserve a risk-benefit analysis based on actual science, not medical mythology The clinical implications for practitioners ready to abandon fear-based prescribing in favor of evidence-based care Episode Resources Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.

In this powerful and eye-opening episode, we welcome Dr. Katie Lee, a trailblazing dentist, visionary entrepreneur, and author of "Saved by the Mouth." Dr. Lee is on a mission to reframe how we think about oral health—not as an isolated part of the body, but as a foundational element of systemic and especially female health. Dr. Lee's journey began at just 14 years old when a traumatic ATV accident forever changed her life. After enduring nine surgeries and dental implants, she learned firsthand the profound impact a healthy smile can have on a person's physical, emotional, and mental health. That experience sparked a calling to become the best dentist she could be—not just to treat teeth, but to heal the whole person. As the founder of The Collective Health Society, a groundbreaking fully integrated functional dental and medical center, Dr. Lee is at the forefront of oral-systemic health. She also serves as the Chief Clinical Advisor for the Dental Innovation Alliance and contributes to groundbreaking space health research with NASA, helping protect astronauts' oral microbiomes during space travel. In this episode, Dr. Lee unpacks the critical but overlooked links between oral health, fertility, and women's overall wellness. She challenges the outdated research models that treat women as "small men" and calls for a more holistic, ecosystem-based approach to women's health. What You'll Learn in This Episode:

In this conversation, Dr. Shawn Tassone discusses the complexities of nicotine, its historical context, biological effects, and personal experiences with its use. He emphasizes the importance of understanding both the potential benefits and risks associated with nicotine, particularly in relation to cognitive function and addiction. The discussion also touches on the broader implications of nicotine use in society and the need for informed decision-making regarding its consumption. Episode Highlights Dr. Shawn Tassone licensing updates in 42 states. How The Hormone Balance Bible outlines common hormone imbalances and solutions The historical significance of nicotine Nicotine is a psychoactive agent found in tobacco Positive and negative biological effects of nicotine Nicotine effects on cognitive function and memory. Why addiction potential is a significant concern with nicotine use Personal experiences with nicotine can vary widely among individuals Nicotine pouches as an alternative Consultation with a healthcare provider is essential before trying nicotine Episode Resources Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.    

“Your normal is different than everybody else's.” There's so much misinformation out there about hormones. The misunderstanding of the Women's Health Initiative findings did massive damage to women's health. It basically ruined an entire generation of physicians who now buy into the false narrative on the dangers of hormone replacement. Today I'm doing a review episode all about my book, The Hormone Balance Bible. I wrote the book not for you to read from cover to cover but so that you can look at the relevant sections as you go through certain stages of your life. In The Hormone Balance Bible, I break down the 12 hormonal archetypes and what to do to start the healing journey for each one.  For this episode,  I'm talking about how you can start figuring out which archetype you are, the characteristics of each type, symptoms you might be noticing, the kinds of women I see in my practice for each archetype, and more. Enjoy the episode!   Highlights The concept and creation of the Hormone Balance Bible How I came up with the twelve hormonal archetypes Why it was important to me to include processes with which women could heal themselves Archetype #1: The Queen - Estrogen Dominance Archetype #2: The Unbalanced Heroine - Progesterone Deficiency Archetype #3: The Mother - High Estrogen, Low Progesterone Archetype #4: The Wise Woman - Menopause Archetype #5: The Workaholic - Excess Cortisol Archetype #6: The Saboteur - Low Cortisol Archetype #7: The Nun - Low Testosterone Archetype #8: The Warrior - High Testosterone Archetype #9: The Underdog - Hypothyroidism/Subclinical Hypothyroidism Archetype #10: The Overachiever - Hyperthyroidism Archetype #11: The Chairwoman - Estrogen Dominance + Excess Cortisol Archetype #12: The Philosopher The medical system's poor treatment of menopausal women Episode Resources: Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.

Today on The Hormone Genius Podcast, we are so excited to welcome Maddy Pollack—a passionate Integrative Nutrition Health Coach, Hormone Health Coach, and Yoga Instructor who specializes in helping women take control of their menstrual and hormonal health naturally. Maddy's journey is incredibly powerful. At just 24 years old, she was diagnosed with Stage 2 Hodgkin's Lymphoma. That life-altering experience sparked a deep curiosity and commitment to understanding the why behind her illness—and ultimately led her to uncover the often-overlooked connection between nutrition, hormone balance, and emotional wellness. Now fully in remission, Maddy dedicates her work to guiding women in naturally reducing PMS symptoms, balancing their hormones, releasing stubborn weight, and reconnecting with their bodies—without relying on medication. In our conversation today, we dive into: The missing link between traditional medical treatment and nutritional healing How to naturally regulate your cycle and ease PMS, and heal from PCOS The impact of stress, gut health, and lifestyle on hormone function Practical, empowering tips for working with your cycle instead of against it Maddy brings a compassionate, science-informed approach to wellness, and I know our listeners are going to walk away with so many actionable insights.

In this episode, Dr. Shawn Tassone discusses the importance of pap smears in women's health, addressing recent misinformation and the historical context of cervical cancer screening. He emphasizes the significance of regular screenings, the role of HPV, and the process of pap smears, while debunking myths propagated by health influencers. Dr. Tassone advocates for informed health choices and the necessity of understanding the medical procedures that can prevent cervical cancer. Episode Highlights: Pap smears and cervical cancer prevention Misinformation about pap smears  How cervical cancer rates have significantly decreased due to screening The history of the pap smear HPV and cervical health Why regular screenings are important The pap smear process Understanding results from pap smears  Health influencers and the spread of dangerous misinformation Episode Resources: Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.    

Why is it so important for both men and women to understand the physiology of sexual intimacy? In this eye-opening episode of The Hormone Genius Podcast, Jamie and Teresa are joined by Dr. Liz Jones, a leading pelvic floor physical therapist from Bismarck, ND, to unpack one of the most sacred, yet misunderstood, aspects of the human experience: sexual intimacy. Dr. Liz brings 20 years of expertise treating complex men's and women's pelvic health conditions at Jones Physical Therapy, the clinic she co-founded with her husband, Joe. Together they've helped countless patients find healing in areas often clouded by shame, fear, or misinformation. This episode dives into both female and male pelvic floor therapy, with a special emphasis on common but often overlooked concerns in men, including: Erectile dysfunction Varicoceles Internal and external hemorrhoids Chronic pelvic pain Pain or fear related to intimacy For many men, these conditions go unspoken and untreated, often leading to emotional and relational strain. Dr. Liz helps normalize these issues and provides practical, hope-filled insight into how pelvic floor therapy can restore function and confidence. She is one of the few physical therapists who treats internal hemorrhoids and has developed a reputation for tackling difficult cases with compassion and clinical excellence. Also covered in this episode: Why understanding the biological design of sexual intimacy can dismantle harmful myths How cultural portrayals of sex often create false expectations and deepen insecurities The spiritual battle around sexual intimacy—and why healing in this area is so deeply needed How understanding the sacredness of the body, especially the pelvic region, can transform your approach to love, marriage, and personal health Whether you're a man experiencing one of these pelvic health challenges, a woman longing for better understanding in your marriage, or someone seeking healing in this vulnerable area—this episode is for you. Dr. Liz Jones, a wife, mother of five, and fierce advocate for pelvic health, reminds us that intimacy is not just physical—it's spiritual, emotional, and deeply human. Find her at https://jonespt.com/ elizabeth@jonespt.com You'll walk away with: A better understanding of how the pelvic floor works—for both men and women Hope for healing, connection, and confidence Practical steps toward restoring intimacy and trust in your relationship Don't miss this powerful and necessary conversation. Listen, share, and help us spread truth and healing.

In this episode Dr. Shawn Tassone and Maddie discuss various topics related to women's health, including the impact of AI on medical practices, the debunking of health myths, the rise of health tech, and the importance of understanding study validity. They also touch on the ethics of health influencers and the credibility of health products in the market. Episode Highlights: Why AI is likely to replace certain medical specialties. Why misinformation in women's health is a significant concern. How health trends often lack scientific backing. Continuous glucose monitor trend How online claims about health products often outpace actual results. Why it's essential to critically evaluate health studies and their methodologies. Reasons consumers should be informed and skeptical of health claims. Why fear-based marketing is prevalent in health products. Not all health influencers are credible; many promote products for profit. Why if a health claim sounds too good to be true, it probably is. Episode Resources: Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.    

Do you have heavy periods, feel bloated, have headaches, bad PMS, or struggle with infertility and/or fibroids? Have you ever considered that these symptoms—and many more—could be related to a hormone imbalance? Estrogen dominance is one of the most commonly misunderstood hormone issues. In this episode, we take a deep dive into what estrogen dominance actually means. We explore the critical role of your liver and gut in estrogen detoxification and how dysfunction in these systems can lead to symptoms like heavy periods, breast tenderness, anxiety, fatigue, and stubborn weight gain. You'll learn how your liver goes through a two-phase detox process to neutralize estrogen, and how the gut's microbiome—including the estrobolome—can either help or hinder that elimination process. We also unpack a lesser-known but powerful enzyme called beta-glucuronidase, which can cause estrogen that was supposed to be excreted to be reabsorbed back into the body—essentially recycling hormones and contributing to estrogen dominance. This often happens when gut health is compromised due to dysbiosis, constipation, or poor diet. Whether you're in your reproductive years, navigating perimenopause, this episode will help you better understand the physiology behind estrogen dominance and how to begin addressing it at the root. We Heart Nutrition offers high-quality supplements designed specifically for women's health. Here are three standout features: Bioavailable Ingredients: Their supplements use the most absorbable forms of each nutrient, ensuring your body gets what it needs. Third-Party Tested: All products are tested for purity and potency, manufactured in NSF & cGMP certified facilities. Purpose-Driven: 10% of every purchase supports pregnancy care centers, aligning with their pro-life mission. Visit weheartnutrition.com and use code GENIUS for 20% off your first order. Medical disclaimer: The information presented in The Hormone Genius Podcast is for informational purposes only and is not intended to be a substitute for actual medical or mental health advice from a doctor, psychologist, or any other medical or mental health professional.

In this episode, Dr. Shawn Tassone discusses the nomination of Casey Means as Surgeon General, exploring her background, credentials, and the implications of her appointment. He critiques the healthcare system, the role of functional medicine, and the influence of nutrition on health. Dr. Tassone emphasizes the importance of questioning the narratives presented by health influencers and the potential impact of the Surgeon General's role on public health policy. Episode Highlights The nomination of Casey Means Questions about her qualification Casey Means educational background Thoughts on her residency Why disillusionment in medicine is common, but quitting is controversial Why functional medicine practices are critiqued as potentially exploitative Reasons continuous glucose monitoring is viewed as a money-making scheme Evaluating Casey Means' statements which may lack evidence How the Surgeon General's role is often more symbolic than powerful Episode Resources: Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Thank you to our sponsor, Endurance Products Company! After over 25 years of practicing medicine, I'll be the first to tell you that not all supplements are created equal. But when I discovered Dihydroberberine SR, by Endurance Products Company, I was genuinely impressed.  It's highly bioavailable and outperforms standard berberine at significantly lower doses. You can explore their offerings at endur.com. Not only is the science solid, but I love that Endurance Products Company is a family-run American company that has cared about doing things right since 1978. I've started recommending Dihydroberberine to my patients who struggle with blood sugar management, and the results speak for themselves. So much so, that I personally take this supplement for helping to support healthy blood sugar levels, heart health, and tap into how my body uses fats for energy As a special offer for my audience, Endurance Products Company is providing a 10% discount on your order! Simply use the code DRT10 at checkout when you visit endur.com. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.  

Today we're diving into how to source peptides safely.  We'll talk about why where you live matters, how to find a reputable provider, and the red flags to watch out for. So if you've been curious about peptides but unsure where to start, this podcast is for you.  Why Peptides? And Why You Need to Be Cautious So first, what are peptides? In short, they're short chains of amino acids—basically, the building blocks of proteins—that signal your body to perform specific actions. Some stimulate growth hormone, others help with weight loss, repair tissue, or improve cognition. Sounds amazing, right? And they can be. But, only when used safely and under the guidance of a qualified provider. Peptides aren't regulated the way pharmaceuticals are, so it's incredibly easy to run into unlicensed sources, impure peptides, or outright scams. Why Where You Live Matters Let's talk geography for a minute. Depending on where you live—whether that's in the U.S., Canada, Mexico, or Europe and other parts of the world—the legal status and availability of peptides vary widely. In the U.S., many peptides are still considered “research chemicals,” meaning they can be sold online but not legally for human use unless prescribed by a licensed provider working with a compounding pharmacy regulated by the FDA. In Canada, peptides are more restricted, and access may require going through clinical trials or specific wellness clinics. Interestingly, in parts of Europe, peptides like BPC-157 have been in clinical use since the 1990s, as it was originally developed and researched in Croatia. So what's the takeaway? The laws in your region affect what's legal, what's safe, and what kind of provider you should be working with. That's why it's important to find someone who not only understands peptide therapy but also works within your country's regulatory framework. How to Find a Reputable Peptide Therapy Provider So now you're wondering: Okay, then who DO I trust? Great question. Let's go over some things you should look for when wanting to start a particular peptide therapy. Credentials Your provider should be a licensed clinician—an MD, DO, PharmD, PA, or NP—with specific training in peptide therapy, functional, or regenerative medicine. Bonus points if they're certified by organizations like SSRP (Seeds Scientific Research & Performance), the A4M (American Academy of Anti-Aging Medicine), or IFM  (Institute for Functional Medicine). Provider Works with Licensed Compounding Pharmacies or Peptide Manufacturers Avoid providers who suggest buying your peptides online or mixing them at home. Thorough Evaluation Process Prior to Treatment The first and most critical step in a full medical workup is gathering a comprehensive medical history. This includes a detailed review of your personal health background—such as any chronic conditions, previous illnesses, surgeries, or hospitalizations—as well as your current medications and supplements. Your provider will also explore your family medical history to identify any contraindications to peptide therapy. Laboratory testing may be obtained if clinically indicated depending on the particular peptide therapy and based on your symptoms, medical history, and treatment goals. Another key component of a full medical workup is the functional assessment, which goes beyond lab numbers to evaluate how your body is actually performing day to day.  This includes an in-depth discussion of your sleep quality, energy levels, cognitive function, mood, libido, and overall sense of well-being. Your provider may also ask about your ability to recover from exercise, your stress resilience, and whether you're experiencing symptoms like brain fog, fatigue, or low motivation. For those seeking peptide therapy for performance or longevity, this assessment helps establish baseline functioning and goals, so treatment can be tailored not just to correct deficiencies, but to optimize quality of life and daily performance. Follow-up Care and Dosing Guidance Peptides aren't one-size-fits-all. You need personalized dosing, cycle recommendations, peptide stacking, and monitoring. If you're not getting that, you're not being cared for safely. Red Flags  “For research only” Let's get real and talk about some red flags you may come across when doing your research. The internet is full of what I like to call “peptide pirates.” These are websites that sell cheap peptides labeled “for research only.” They might even look legit, but here's the thing, there's no regulation, no guarantee of purity or potency, and no support during your peptide therapy journey. Low cost and hidden fees Keep in mind that peptides are often expensive due to several factors. They require complex, specialized manufacturing processes, which include synthesis and purification to ensure quality and purity. Additionally, high-quality peptides are typically produced in small batches by licensed compounding pharmacies or peptide manufacturers, which increases costs. The research and development and regulatory compliance required to ensure their safety and efficacy also contribute to the higher price point.  If the prices from online peptide providers/clinics seem unusually low or too good to be true, there's a high likelihood that the products are either compromised, unregulated, or not what they claim to be. And while we're on the topic of cost, I shouldn't forget to mention hidden fees. You know, the sneaky little charges that pop up after you've been lured in by the words “free consultation.” When you book that initial appointment thinking, “Okay, great. I'll get expert advice, ask a few questions, and figure out if peptide therapy is right for me.” But then what happens? What if you've got more questions after the appointment—maybe you're dealing with side effects, started a new medication and want to be sure there aren't any interactions, or your symptoms have shifted and you're thinking about adjusting your dosage. And just like that, your “free” consultation suddenly comes with a consult price tag. I've personally seen clinics charge $50 just to email a follow-up question or do a “dosage review”. And don't get me started on the “lab interpretation fees.” You either pay for your bloodwork or labs are included, but then they charge you again just to tell you what your results mean.  Cold-chain And lastly, let's not forget that peptides are delicate compounds that require specific storage conditions. Certain peptide providers may not store or ship peptides correctly, affecting their potency and stability. As a general rule, for long-term storage, peptides should be kept frozen in their lyophilized (powder) form to preserve stability. Once reconstituted, most peptides should be stored in the refrigerator and used within the recommended timeframe, typically 2–8 weeks depending on the peptide and diluents used. It's important to avoid repeatedly freezing and thawing, as this can degrade the peptide structure and reduce its effectiveness.  Recap Do your homework. Research providers in your area. Look for peptide clinics or functional or integrative clinics with peptide experience. Ask smart questions. Where do they source peptides? Are the peptides made in a cGMP, FDA-registered facility? What's their follow-up protocol? How do they store and ship their peptides? Trust your gut—and the science. If something feels off, it probably is. Safe peptide therapy is always grounded in evidence and ethical practice. Your health isn't something to gamble with. Peptides can be powerful tools—but only from a trusted source and with guidance. Thank you for listening to The Peptide Podcast. If you enjoyed the show and want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going.  Have a happy, healthy week!

In this episode, Dr. Shawn Tassone discusses the complexities and controversies surrounding functional medicine and its distinction from integrative medicine. He critiques the rise of functional medicine practitioners, highlighting issues of credibility, ethical practices, and the commercialization of health services. Dr. Tassone emphasizes the importance of informed consumer choices in navigating the healthcare landscape, particularly in the context of hormone health and wellness. Episode Highlights: Why prevention should be emphasized as a key aspect of healthcare How functional medicine has become as corrupt as traditional medicine The truth about many self-proclaimed functional medicine practitioners who lack proper medical credentials How Integrative Medicine focuses on a team approach to patient care Functional medicine's origins are rooted in addressing chronic diseases Why the criticism of functional medicine includes its reliance on unnecessary testing Reasons consumers should be wary of health scams and marketing tactics How informed consumerism is crucial in the healthcare industry Episode Resources: Dr. Shawn Tassone's Practice | https://www.drshawntassone.com Dr. Shawn Tassone's Book | The Hormone Balance Bible Dr. Shawn Tassone's Integrative Hormonal Mapping System | Hormone Archetype Quiz Thank you to our sponsor, Purality Health! The question isn't which supplements to take—it's whether your body can absorb them. Most traditional supplements fall victim to stomach acid before delivering benefits. Purality Health's micelle liposomal technology creates a double-layer protective system that shields nutrients from stomach acid destruction while facilitating direct bloodstream absorption—making supplements up to 800% more effective. For perimenopausal and menopausal patients, I recommend their Vitamin D3 with K2 for bone density and mood regulation, and their exceptional magnesium formula for sleep and muscle tension. As a physician, I value their commitment to quality: cGMP-compliant facilities, purity testing, and organic, non-GMO ingredients without unnecessary fillers. Visit puralityhealth.com/drshawn and use code DRSHAWN for exclusive savings. Thank you to our sponsor, Endurance Products Company! After over 25 years of practicing medicine, I'll be the first to tell you that not all supplements are created equal. But when I discovered Dihydroberberine SR, by Endurance Products Company, I was genuinely impressed.  It's highly bioavailable and outperforms standard berberine at significantly lower doses. You can explore their offerings at endur.com. Not only is the science solid, but I love that Endurance Products Company is a family-run American company that has cared about doing things right since 1978. I've started recommending Dihydroberberine to my patients who struggle with blood sugar management, and the results speak for themselves. So much so, that I personally take this supplement for helping to support healthy blood sugar levels, heart health, and tap into how my body uses fats for energy As a special offer for my audience, Endurance Products Company is providing a 10% discount on your order! Simply use the code DRT10 at checkout when you visit endur.com. Medical Disclaimer This podcast and website represent the opinions of Dr. Shawn Tassone and his guests. The content here should not be taken as medical advice and is for informational purposes only. Because each person is so unique, please consult your health care professional for any medical questions.

In this episode of The Hormone Genius, we sit down with Haley Yeager to explore a topic every woman deserves to understand—how charting your cycle can be a life-changing tool for health, healing, and wholeness. Contrary to popular belief, menstrual cycle charting isn't just for family planning. It's one of the most powerful insights a woman can have into her overall health. A well-charted cycle acts like a monthly report card, revealing signs of hormonal imbalances, fertility struggles, or conditions like PCOS and endometriosis. It's not just about reproduction—it's about connection with your body. We also discuss the widespread use of hormonal birth control as a catch-all solution for reproductive concerns. While the pill may manage symptoms, it often masks the real issue, delaying diagnosis and treatment. True healing begins with understanding what's actually happening in the body—and that starts with cycle awareness. Haley shares her own powerful journey. At 16, she was prescribed the pill to manage irregular periods but quickly experienced intense side effects. Unsatisfied with masking symptoms, she turned to cycle charting and, through the help of a knowledgeable OBGYN, was diagnosed with PCOS. This shift allowed her to manage her health naturally—and ultimately led to the conception of her three beautiful children.

Chatterheads, for those who have been with us since the Sunday Shenanigan days, stuck around for last season's Midweek Meltdowns... Somehow, WE'VE BEEN RENEWED FOR SEASON 3 here at Tables, Ladders, and Chatter! Tonight we bring our best analysis of the weeks following Wrestlemania 41, discuss theories leading into Backlash... And Tommy Gunns gives his "State of Wrestling" address to continue his reign as TLC Predictions Champion!Thanks To Our Sponsors:Reaper Apparel Co⁠⁠⁠⁠⁠⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order!⁠⁠⁠⁠⁠⁠Psycho Pharma⁠⁠⁠⁠⁠⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

Documentation Hierarchy and Best Practices in Quality Systems with Aaron SnyderIn this episode of Let's Combinate, host Subhi Saadeh is joined by Aaron Snyder, the creator of Quality Systems Explained and a seasoned consultant in regulated quality systems. The discussion revolves around the critical role of documentation in quality systems, which serves as the backbone of compliance. Key topics include the hierarchy of regulations, document management best practices, the intricacies of quality manuals, and the critical distinctions between SOPs and work instructions. Additionally, they explore the interconnectedness of document control and training, emphasizing the importance of defined roles and responsibilities within organizations. Listeners are provided with insights into establishing and maintaining effective documentation systems while ensuring adherence to regulatory requirements.00:00 Introduction and Guest Introduction00:37 The Importance of Documentation in Quality Systems01:30 Hierarchy and Structure of Documentation02:44 Standard Operating Procedures (SOPs) vs. Work Instructions11:22 Document Control and Change Management15:52 Roles and Responsibilities in Quality Systems18:20 RACI Matrix and Its Importance20:47 Common Issues in Documentation and Training25:25 Conclusion and Where to Find More InformationAaron Snyder is a quality management systems expert and the founder of Quality Systems Explained. He previously served as VP of QA at Allotex and has held roles at Fresenius Kabi, Molnlycke, Waters Corporation, Covidien, Cardinal Health, and General Electric. With extensive experience across pharmaceuticals, medical devices, and combination products, Aaron is also a member of the AAMI Faculty, teaching several courses on various QMS topics. An avid content creator, he dissects, presents, and teaches QMS and cGMP topics on his YouTube channel, Quality Systems Explained.Subhi Saadeh is a Quality Professional and host of Let's Combinate. With a background in Quality, Manufacturing Operations and R&D he's worked in Large Medical Device/Pharma organizations to support the development and launch of Hardware Devices, Disposable Devices, and Combination Products for Vaccines, Generics, and Biologics. Subhi serves currently as the International Committee Chair for the Combination Products Coalition(CPC) and as a member of ASTM Committee E55 and also served as a committee member on AAMI's Combination Products Committee.For questions, inquiries or suggestions please reach out at letscombinate.com or on the show's LinkedIn Page.

Chatterheads, It's that time of the year once again and we've come full circle... The Big 4 Predictions has been a wild ride and Tommy Gunns still holds the title... But will he remain the champion after this weekend's Wrestlemania 41 in Las Vegas, Nevada... Only time will tell and may Lady Luck be on his side!⁠⁠⁠Reaper Apparel Co⁠⁠⁠⁠⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order!⁠⁠⁠⁠⁠Psycho Pharma⁠⁠⁠⁠⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

What a chaotic week it's, been Chatterheads... And to bring it all into perspective with their own cynical twists are your three faithful hosts, Tommy Gunns, Ponyboy, and Zero! Let's not waste anymore time, it's time for MIDWEEK MELTDOWN!⁠⁠⁠Reaper Apparel Co⁠⁠⁠⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order!⁠⁠⁠⁠Psycho Pharma⁠⁠⁠⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

Chatterheads, Tommy Gunns has taken the night off to spend time with his family, on that note.... Looks like you're stuck with the brothers; Ponyboy and Zero for this next installment of Midweek Meltdown as we enter the final weeks before Wrestlemania 41!⁠⁠⁠Reaper Apparel Co⁠⁠⁠⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order!⁠⁠⁠⁠Psycho Pharma⁠⁠⁠⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

In this latest episode of Proven Health Alternatives, I sit down with Dr. Eric Viegas, a Medical Product Manager, to break down the booming supplement industry and its crucial role in modern health. We discuss why supplements are essential for many people today—helping to fill critical nutrient gaps in our diets. But with that rise in demand comes a major challenge: quality control. Dr. Viegas sheds light on the risks of low-quality supplements, from inconsistent potency to contamination, and shares key strategies for ensuring product credibility—like looking for third-party testing and CGMP certifications. Whether you're a practitioner or a health-conscious consumer, this episode will help you navigate the supplement market with confidence and make informed choices for better health. Key Takeaways: Supplement Quality Indicators: Learn how third-party CGMP certification and brand credibility play critical roles in ensuring safe and effective dietary supplements. Understanding Fillers and Forms: Dr. Viegas explains the importance of bioavailability in nutrient absorption, specifically how certain forms like chelated minerals are superior. Top Supplement Choices: The discussion includes various popular supplements like magnesium, omega-3s, and probiotics, and offers insights into their best applications and benefits. Role of Practitioners: Emphasizing the need for practitioner guidance in supplement selection, the episode discusses how healthcare professionals can integrate quality assessments into patient education. The Danger of Misinformation: Tips on discerning credible supplement information from prevalent misinformation on social media platforms are provided, helping consumers make informed decisions. More About Dr. Eric Viegas: Dr. Eric Viegas is a licensed naturopathic doctor in Ontario, Canada. He is currently serving as the Medical Product Manager and Medical Advisor at Fullscript, where he focuses on whole person care, supplement quality, and practitioner education. With extensive experience in the supplement industry, Dr. Viegas works closely with practitioners to ensure they have access to high-quality, research-backed supplements for their patients. He is passionate about educating both healthcare providers and patients on the importance of proper supplementation and how to navigate the ever-expanding supplement market with confidence.

Officially coming to you live during the official midweek... IT'S MIDWEEK MELTDOWN WITH YOUR WONDERFUL HOSTS TOMMY GUNNS, PONYBOY, and ZERO!!!⁠⁠⁠Reaper Apparel Co⁠⁠⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order!⁠⁠⁠Psycho Pharma⁠⁠⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

I am back!!!!!! And not only am I back BUT this is a VERY SPECIAL release because it is my 50TH episode and it is super appropriate that as I approach my 1 year Anniversary of owning Evergreen Nutrition in Eugene, OR that this episode is shared!   On this episode of Totally Exposed I got to sit down with Allie Hobson from Core Formulas 1/2 of the fabulous duo to the company!  Allie is a FTNP, RWP and she and Emily Morrow saw a huge need for supplements that get back to the basics and foundations.  There is a lot of nasty ingredients used as fillers in supplements and Core Formulas believes in giving the consumer full transparency and clarity on what are Foundational supports.  They are an American made company with no chemical fillers, no artificial anything, tested for purity and CGMP compliant. This episode is for the listener who wants to learn more about what to look for in a supplement and what to stay away from!  So pull up a chair, a cozy blanket and get ready to find all the golden nuggets throughout our talk! 

YAWN!!! Boy it's been a relaxing few weeks away from Midweek Meltdown, and we hope you've all missed us live we've missed you... However, let's not waste any time as we get right back where we left off... Well sorta! ANYWAY, here comes Zero, Ponyboy, and Tommy Gunns... Did ya see what I did there with the title by the way? HA HA HA!... "I'm so lonely..." - Conquest from "Invincible"⁠⁠Reaper Apparel Co⁠⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order!⁠⁠Psycho Pharma⁠⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

Introduction: Guests: Dennis Katz (President) & Michael Macione (VP of Sales & Marketing), founders of Doctor Inspired Formulations Recorded at: ILADS Conference, the largest Lyme disease conference in the world Focus: Providing high-quality, standardized supplements for the Lyme disease community Key Points: Background and Inspiration for Doctor-Inspired Formulations Founded in response to physicians' frustrations over inconsistent supplement quality Initially launched with Mimosa pudica and liposomal artemisinin to ensure proper dosing and purity Challenges in Sourcing and Standardizing Supplements Difficulty in obtaining high-quality, contaminant-free raw materials Rigorous quality control, including certificates of analysis for every batch Expanding Product Line to Meet Lyme Community Needs Grew from 2 to 8 products based on feedback from Lyme-literate doctors and patients Offerings include liposomal curcumin, oregano oil, artemisinin, and Mimosa pudica Enhancing Bioavailability and Reducing Inflammation Use of enteric coating, micronization, and carrier oils to maximize absorption Formulations designed to reduce common side effects Key Products and Their Uses Cinnamon-Clove-Oregano Formula: Supports biofilm disruption and Lyme persisters, included in Dr. Horowitz's protocol Whisbax Topical Spray/Cream: Designed for skin issues like actinomyces and post-tick bite support Commitment to Quality and Customer Service Manufactured in the U.S. in cGMP-certified facilities with stringent testing protocols Small company with a direct line of communication between founders and customers Conclusion: Doctor Inspired Formulations is dedicated to providing standardized, pharmaceutical-grade supplements for the Lyme community Founders emphasize the importance of transparency, quality, and patient-centered innovation Resources & Links:

Dr. Stephanie's Natural Supplements for Health & Wellness - formulated by Dr. Stephanie Redmond, PharmD, CDCES, BC-ADM. The products are crafted to simplify your wellness journey with all-in-one formulas that save you time & money – providing options for weight support, general health, and motherhood. Available for purchase at Amazon, Walmart, CVS, Walgreens, Kroger, and more.  Dr. Stephanie's Natural Supplements for Health & Wellness - formulated by Dr. Stephanie Redmond, PharmD, CDCES, BC-ADM. The products are crafted to simplify your wellness journey with all-in-one formulas that save you time & money – providing options for weight support, general health, and motherhood. Available for purchase at Amazon, Walmart, CVS, Walgreens, Kroger, and more.  https://byebyeweekend.com Key Information: Your Health, Simplified: Taking control of your health with natural solutions shouldn't be overwhelming. Dr. Stephanie's products are crafted to simplify your wellness journey with all-in-one formulas that save you time and money. We've done the research and combined the right ingredients in clinically effective doses to address your specific health needs. Clinically-Backed Doses: Our mission is to create supplements that prioritize efficacy over marketing gimmicks and proprietary doses. Every ingredient and dosage in Dr. Stephanie's products is supported by clinical studies, ensuring that each formula contains enough of the right ingredients to truly make a difference. Clean & High-Quality Ingredients: Your safety is our top priority. Dr. Stephanie's supplements are made in the USA in a cGMP facility and undergo third-party testing to guarantee accuracy, safety, and purity. We source only the highest-quality ingredients, so you can trust what's in every bottle. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Let's Combinate, host Subhi Saadeh is joined by quality systems expert Aaron Snyder to explore the critical quality system element known as CAPA (Corrective and Preventive Action). They dive into the differences between CAPA approaches in the pharmaceutical and MedTech industries, examining their historical and regulatory contexts. Aaron explains how U.S. regulations describe deviations on the pharma side and non-conforming products on the MedTech side, and how these are handled differently under respective quality systems. The conversation also touches on topics like root cause analysis, verification of effectiveness, and the importance of management support in making CAPA systems effective. Aaron highlights the value of continuous improvement and debunks common misconceptions about CAPA in both industries.00:00 Introduction and Guest Introduction00:33 Understanding CAPA in Pharma and MedTech01:08 Regulatory Differences and Their Implications03:12 Event Handling and Investigation Processes08:13 CAPA System Effectiveness13:57 Quality System Approaches in Pharma and MedTech26:22 Root Cause Analysis and Continuous Improvement30:43 Conclusion and Contact InformationAaron Snyder is a quality management systems expert and the founder of Quality Systems Explained. He previously served as VP of QA at Allotex and has held roles at Fresenius Kabi, Molnlycke, Waters Corporation, Covidien, Cardinal Health, and General Electric. With extensive experience across pharmaceuticals, medical devices, and combination products, Aaron is also a member of the AAMI Faculty, teaching several courses on various QMS topics. An avid content creator, he dissects, presents, and teaches QMS and cGMP topics on his YouTube channel, Quality Systems Explained.Subhi Saadeh is a Quality Professional and host of Let's Combinate. With a background in Quality, Manufacturing Operations and R&D he's worked in Large Medical Device/Pharma organizations to support the development and launch of Hardware Devices, Disposable Devices, and Combination Products for Vaccines, Generics, and Biologics. Subhi serves currently as the International Committee Chair for the Combination Products Coalition(CPC) and as a member of ASTM Committee E55 and also served as a committee member on AAMI's Combination Products Committee.For questions, inquiries or suggestions please reach out at letscombinate.com or on the show's LinkedIn Page.

Chatterheads, we are back for another episode of Midweek Meltdown... What can we say? It's Wrestlemania season, but before we get there we have one stop going through Toronto... The Elimination Chamber is less than two week away and what can we say? It's loaded!A special thank you to our sponsors:⁠Reaper Apparel Co⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order!⁠Psycho Pharma⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

In this episode of the Life Science Success Podcast, my guest is Forrest Brown, President of Germfree, a pioneering company in mobile laboratory and biocontainment solutions. With a Summa Cum Laude degree in Biomedical Engineering and an impressive career transforming CGMP facilities, Forrest brings a wealth of strategic leadership and technical expertise to our conversation today. 00:00 Introduction to Life Science Success Podcast 00:42 Sponsor Message: Bio on the Bayou 2025 02:16 Guest Introduction: Forrest Brown of Germfree 02:51 Forrest Brown's Career Journey 06:19 Germfree's Global Reach and Client Engagement 11:01 Challenges and Innovations in Pharmaceutical Solutions 20:48 Leadership and Industry Insights 35:30 Concluding Thoughts and Farewell

Chatterheads, let's cut to the chase... The Royal Rumble has come and gone and while there were some surprise returns... It seemed to be lacking... What do your TLC Boys have to say about it? Tune in and find out NOW on MIDWEEK MELTDOWN! A special thank you to our sponsors: ⁠Reaper Apparel Co⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order! ⁠Psycho Pharma⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

Rounding out the year Chatterheads we have hit the Royal Rumble Prediction SHOW!!! Tonight is a special episode as we give our thoughts and insight as well as lay it all on the line to make our predictions heading into Wrestlemania Season... The Road begins this Saturday!!! A special thank you to our sponsors: ⁠Reaper Apparel Co⁠ - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order!⁠ Psycho Pharma⁠ - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

Chatterheads, welcome back to Midweek Meltdown with your hosts, Tommy Gunns, Ponyboy, and returning from recovery and vacation, Zero!!! Tonight the stakes are high... as we are just one week out from our Royal Rumble Predictions showcase! A special thank you to our sponsors: Reaper Apparel Co - Reaper is not only a brand, its a complete life adjustment. A commitment to live your most authentic way every single day! Use discount code: Zero815 for 10% off your order! Psycho Pharma - Psycho Pharma is a fast-growing company that innovates aggressive formulas to be better than most of the run of the mill products many other brands produce. All Psycho Pharma products are produced in an FDA registered manufacturing facility that follows cGMP standards, with assays on each ingredient and COA's/batch records kept for every run. Use discount code: PONYBOY815 for 20% off your order!

In this episode of the RWS Clinician's Corner, Margaret Floyd Barry meets with one of the world's top supplement formulators, Shawn Wells. Not only does Shawn give us the inside scoop on some really powerful new supplement ingredients and formulations, but he delves into the complex process of creating supplements, improving their bioavailability, and the science behind new, innovative ingredients on the market. We also explore the exciting world of exercise mimetics and their potential health benefits, especially for those unable to train due to severe health conditions. Plus, you'll hear about the exciting new ingredient, paraxanthine, and how it might soon revolutionize the market.  We discuss:   The supplement formulation process, with an emphasis on quality control and compliance How Shawn thinks about developing novel ingredients  Dihydroberine, L-ergothioneine & Spermidine: what they do and why they're important NAD and aging Benefits of Paraxanthine and Dileucine  Using Creatine for health (not just building muscle) - one of Shawn's top recommendations Blood sugar management with ​​Dihydroberine (vs. Metformin) Supplement integrity: key things to watch out for when researching a new product or line The Clinician's Corner is brought to you by Restorative Wellness Solutions.  Follow us: https://www.instagram.com/restorativewellnesssolutions/ Timestamps:  00:00 Mother sold Shackley vitamins; early supplement industry. 06:21 Vitamin C research explores higher doses, benefits. 15:57 Paraxanthine benefits without caffeine's side effects. 20:23 Attention to detail signifies brand quality control. 27:31 Supplements: Can't claim cures, only support wellness. 29:04 High-earning products must be tailored to individuals. 35:04 Restorative Wellness Solutions: Transformative health practitioner training. 43:44 Mitochondrial health is crucial for combating aging. 48:07 NAD declines with age; polyphenols inhibit breakdown. 51:39 No caffeine side effects; boosts nitric oxide, dopamine. 59:44 Optimize leucine spikes for protein synthesis effectiveness. 01:01:53 Mitochondria abundance supports high energy cells. 01:06:51 Join, follow, share, suggest topics, change health. Speaker bio:  Shawn Wells MPH, LDN, RD, CISSN, FISSN is the world's leading nutritional biochemist and expert on health optimization. He has formulated over 700 supplements, food, beverages, and cosmeceuticals and patented 20 novel ingredients including Teacrine, Dynamine and Dihydroberberine and is now known as the “ingredientologist” - the scientist of ingredients.  Formerly a Chief Clinical Dietitian with over a decade of clinical experience, he has counseled thousands of people on innovative health solutions such as keto, paleo, fasting, and supplements. He has also personally overcome various health issues including Epstein-Barr Virus, Chronic Fatigue Syndrome, Fibromyalgia, depression, insomnia, obesity, and a pituitary tumor. As a world-renowned thought-leader on mitochondrial health, he has been paid to speak on five different continents. His insights have been prominently featured in documentaries and podcasts like Ben Greenfield and regularly on morning television. His expertise can help any health-conscious individual to better manage stress and experience greater resilience and more energy through utilizing his practical research-backed solutions. His book, The Energy Formula, has been recognized by both USA Today and Forbes as well as an Amazon best-seller in multiple categories.   Connect with Shawn Wells: Website: https://shawnwells.com/ Instagram: https://www.instagram.com/shawnwells/   And find his book, The Energy Formula, here. Keywords:  supplement formulation, Shawn Wells, dihydroberine, paraxanthine, bioavailability, pharmacokinetics, cognitive function, physiological benefits, metformin alternatives, CGMP certification, exercise mimetics, L-valine, Albeba, insulin sensitivity, mitochondrial health, longevity vitamins, L-ergothioneine, spermidine, anti-aging supplements, NAD levels, NMN vs NR, apigenin, fisetin, autoimmune diseases, gluten sensitivities, paresthesis, caffeine metabolites, dileucine, continuous glucose monitor, acetyl-L-carnitine, creatine Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

Host Emily Walsh Martin, PhD, is joined by Chris Choi, PhD, Roswell Park Comprehensive Cancer Center's Senior Vice President of Industry Partnerships and Technical Director of the center's new Good Manufacturing Practice (cGMP) Facility. Dr. Choi is also an associate professor of oncology. This wide-ranging conversation covers cell therapy development and manufacturing and how the growing Roswell Park Center is aiming to support sponsors in the CAR T and cell therapy space. Emily and Chris also discuss their experiences on cross-functional teams and how a program's research, manufacturing, and clinical elements must be knit together for success. Music by: https://www.steven-obrien.net/--------------------------Bright New Morning - Steven O'Brien (Used for free under a Creative Commons Attribution 4.0 License: https://creativecommons.org/licenses/by/4.0/)Show your support for ASGCT!: https://asgct.org/membership/donateSee omnystudio.com/listener for privacy information.

Send us a textYo, yo, yo, yo...how are all you Vipers doin? Mr and Mrs Weedman are getting normal with a sesh of Sub Zero from their friends @MidwestTerps.  They share their latest adventures from the Chicagoland cannabis scene and then get right into delivering some big cannabis articles, reports, political news, and stories from all around this big beautiful world.  Mr Weedman shares a study from the National Cancer Institute where researchers tracked cannabis use data from cancer and pain therapy patients, another report talking about the potential for cannabis use to build confidence, and a story on the need for policy change to support out-of-pocket costs for medical cannabis patients.  Mrs. Weedman shares a perspective on cannabis use during pregnancy, the unknown risks of using cannabis while taking Ozempic, and an in-depth report on the benefits of cGMP compliance being initiated in cannabis production facilities prior to being required, and much more. Thanks for listening and as always, hit us up!TWITTER: @weedman420podIG: @weedman420chronicles2.0YouTube: Weedman420 ChroniclesEMAIL:  weedman420chronicles@gmail.comSHOP: www.eightdecades.comIG: @eightdecadesEMAIL: eightdecadesinfo@gmail.com#ImHigh #Cannabis #StomptheStigma #HomeGrow #FreethePlant #Stoners #Burners #rosin #liverosin #Potheads #Vipers #CannabisEducation #CannabisResearch #Weed #Marijuana #LegalizeIt #CannabisNews #CBD #Terpenes  #Podcast #CannabisPodcast #eightdecades #LPP #Lifestyle #HealthyLifestyle #NaturalMedicine #PlantMedicine #News #Research #MedicalMarijuana #Infused #420 #Education #Health #Wellness #WorldNews #Gardening #budtender #kief #hemp #dabs #hash #joints #edibles #gummies #tincture #vapes #esters #pauliesayssmokesmartArticle Links:* https://www.marijuanamoment.net/federal-agency-examines-core-questions-about-medical-marijuana-for-cancer-including-as-an-opioid-alternative-to-treat-pain/* https://www.mercurynews.com/2024/09/25/can-marijuana-help-you-build-confidence/* https://thefreshtoast.com/culture/can-you-consume-marijuana-on-ozempic/* https://www.marijuanamoment.net/most-pain-patients-and-doctors-support-legalizing-medical-marijuana-and-having-insurance-companies-cover-the-cost-ama-study-shows/* https://www.cannabissciencetech.com/view/how-regulation-and-quality-assurance-can-ease-fears-about-cannabis-legalization-ahead-of-a-critical-electionCOPYRIGHT 2021 WeedMan420Chronicles©

Part 4 of 4. My guest for this week's episode is Derek Hennecke, a veteran biotech entrepreneur and board member with over 30 years of experience in the CDMO industry, whose mission is to support the biotech revolution and create value for patients, customers, and investors. In addition to his Board work, Derek previously held leadership positions at DSM and was the Founder and CEO of Xcelience, a Florida-based CDMO specializing in preformulation, micronization, analytical services, formulation development, cGMP manufacturing, and more. Derek eventually sold Xcelience to Capsugel (now Lonza) in 2016. His extensive pharma and cell therapy expertise makes for an insightful conversation that founders can learn from.

From simple biomarker tests to cutting-edge precision medicine, the diagnostics industry is navigating a complex landscape of regulatory changes and technological advancements. In this episode, Andrew L'Huillier, a leader in the diagnostics industry and Director of Regulatory Affairs Liaison - Diagnostics at Merck, discusses his work on FlowScript and other groundbreaking diagnostic products. Learn about the challenges and opportunities in regulatory compliance, drug discovery, and the implementation of cGMP guidelines. Tune in and discover how precision medicine is revolutionizing healthcare and improving patient care! Resources: Connect with and follow Andrew L'Huillier on LinkedIn. Follow Merck on LinkedIn. Explore the Merck Website! Subscribe to the CDER, CBER, and CDRH newsletters! Discover AgencyIQ and 360Dx!

"For most American adults, a strong foundation in supplementation can be built with five key nutrients: a high-quality multivitamin, magnesium, omega-3 fatty acids, probiotics, and digestive enzymes."Are you frustrated by the lack of transparency in the supplement industry?Overwhelmed by the endless options and claims on supplement labels?Unsure how to distinguish high-quality, effective products from ineffective ones?Join us as we chat with Jared St. Clair of Vitality Nutrition and host of the Vitality Radio Podcast about the often convoluted world of dietary supplements. In this episode, Jared pulls back the curtain on questionable practices by some companies and shares his 'vital five' must-have supplement recommendations.Learn how to spot trustworthy brands that prioritize your health over profit, and gain adept knowledge on supplementing wisely. Tune in to Season 3, Episode 17 of the Gutsy Health Podcast! Show Highlights: 00:00 - Episode start02:25 - Jared's background as health store manager turned owner and radio show host 12:52 - The impetus for creating his own product line of supplements17:28 - Jared shares his "vital five" supplement recommendations18:28 - Why multivitamins like Centrum are a waste of money25:41 - Praise for companies with high-quality standards and commitment to purity29:13 - Direct-to-consumer business models that allow for higher quality at lower prices33:05 - Risks of long-term use of proton pump inhibitors (PPIs) 34:14 - cGMP (current Good Manufacturing Practices) in the supplement industry36:10 - Are fillers and flow agents in supplements something to be mindful of?39:50 - Differences between synthetic and natural/food-based sources of nutrients47:59 - Why you need more magnesium and methylated B vitamins49:25 - Voting with your dollars to support ethical companies and drive real change50:33 - Jared's top picks for omega-3 supplements58:18 - How and where to start your supplement journey1:00:52 - The gut-brain connection and the link between IBS and depression1:06:19 - Guidance on selecting a high-quality probiotic supplementImportant Links: Gutsy Health Website - https://www.mygutsyhealth.com/Gutsy Health Podcast IG - https://www.instagram.com/gutsyhealthpodcast/Reach out to Provo Health and schedule a consultation with Dr. Jeff Wright by calling 801-691-1765Connect with Jared St. Clair on:Vitality Nutrition - https://vitalitynutrition.com/Vitality Radio Podcast with Jared St. Clair - https://podcasts.apple.com/us/podcast/vitality-radio-podcast-with-jared-st-clair/id1499760048Instagram - https://www.instagram.com/vitalitynutritionbountiful/Reach out to Vitality Nutrition by calling 801-292-6662 or visit the shop on 107 South 500 West, Bountiful, UT 84010Links Mentioned:Jared's Vital 5 - https://vitalitynutrition.com/collections/vital-5Just Ingredients Podcast with Karalynne Call - https://podcasts.apple.com/us/podcast/just-ingredients/id1557557205The Great Debate  in Probiotics: Human Strains vs. Spores - https:Send us a Text Message.