Podcasts about Great Ormond Street Hospital

In this episode we are exploring rare and ultra-rare disease in honor of Rare Disease Day on February 28 which raises awareness for the 300 million people worldwide living with a rare disease. We are talking with one author about their study on the role of digital tools in rare disease management and another author about their research into experiences of parents who have a child with an emerging-ultrarare disorder. Segment 1: Exploring the role of digital tools in rare disease management: An interview-based study Andrea Chang works as a Genomic Science Liaison at Quest Diagnostics and earned her MS in Genetic Counseling from UCLA's inaugural genetic counseling class. In this segment we discuss: The role of digital tools in healthcare management for rare diseases Real-world examples of existing digital tools for the rare disease community The impact of rare disease on the global population The healthcare gaps currently not addressed by digital tools Recommended digital tool features Segment 2: The book is just being written: The enduring journey of parents of children with emerging- ultrarare disorders Bethany Stafford-Smith works clinically as a genetic counsellor at University Hospitals of Leicester. She also works for Great Ormond Street Hospital as a Research Genetic Counsellor. In this segment we discuss: The definition of emerging ultra rare disorders or E-URD Experiences of parents with children diagnosed with an E-URD Parents' perceptions on the utility of a diagnosis Challenges faced by parents seeking medical and social support after receiving an E-URD diagnosis for their child How researchers and healthcare providers can support advocacy in E-URDs Would you like to nominate a JoGC article to be featured in the show? If so, please fill out this nomination submission form here. Multiple entries are encouraged including articles where you, your colleagues, or your friends are authors. Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”.  For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others.  Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com.  DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Sydney Arlen.

Topics covered : Anorexia, grief, shame, perfectionism, recovery, gratitude, the inner critic, CBT, social media, filters, boxing, meditation, femininity, spirituality, letting go.In this episode I speak to one of the most impressive people I've ever met, boxer Mary Kate Slattery.Originally from Dublin, Mary Kate spent parts of her childhood in Lahinch in Co. Clare.She's the eldest of three girls, a law graduate from Trinity College Dublin and when she was only 9 she developed anorexia. She spent time in and out of Crumlin children's hospital in Dublin and eventually had to go to London to receive treatment at Great Ormond Street Hospital for Children.In this conversation we speak about her battle with anorexia, perfectionism, therapy, meditation, femininity, letting go and her love of boxing.It's such an inspiring yet challenging conversation in parts, so please be aware before you listen.Also as you can hear in this episode, Mary Kate is very thankful to her psychiatrist Fiona McNicholas for helping her recover from anorexia and if you're worried about yourself or someone you love, you can reach out for help here...Bodywhys | The Eating Disorders Association of Ireland Hosted on Acast. See acast.com/privacy for more information.

Our guest this week is James Burch, of Georgetown, Grand Cayman, who is a corporate law partner at Walkers, amateur boxer and single father of three young boys, including one with global developmental delays.James was born and raised in Chelton, England.  After obtaining his educaiton and becoming a lawyer he has worked overseas in Hong Kong and Grand Cayman. James and his x-wife, Gemma, were married for 9 years before divorcing seven years ago and are the proud parents of three boys: Charlie (10), Harry (12) and Archie (14), who suffered brain damage at the time of his birth and who has global developmental delays.There were complications with Archie's birth that required he be medievacked to Miami for emergency surgery, so on a moments notice, James joined Archie on the flight to Miami and didn't return to Grand Cayman for three years. James' is one of those stories, that "in the blink of an eye" life as you know is over.  It was a surreal experience and fortunately Archie is a miracle child. We also learn about James' interest in boxing, which is leading to his first professional fight in Columbia, in May at age 48.It's an inspiring story about a father's commitment to his children and overcoming adversity all on this week's episode SFN Dad to Dad Podcast.Show Notes - Phone/WhatsApp – 1-345-926-9588Email – James.Burch@walkersglobal.comLinkedIn –  https://www.linkedin.com/in/james-burch-42041510/Great Ormond Street Hospital for Children - https://www.gosh.nhs.uk/Register for the 6th Annual SFN Dads Virthual Conference on May 10, 2025: https://us02web.zoom.us/meeting/register/TLkN_ViJTTqnaK-M8pHPNA After registering, you will receive a confirmation email containing information about joining the meeting.Special Fathers Network -SFN is a dad to dad mentoring program for fathers raising children with special needs. Many of the 800+ SFN Mentor Fathers, who are raising kids with special needs, have said: "I wish there was something like this when we first received our child's diagnosis. I felt so isolated.  There was no one within my family, at work, at church or within my friend group who understood or could relate to what I was going through."SFN Mentor Fathers share their experiences with younger dads closer to the beginning of their journey raising a child with the same or similar special needs. The SFN Mentor Fathers do NOT offer legal or medical advice, that is what lawyers and doctors do. They simply share their experiences and how they have made the most of challenging situations.Check out the 21CD YouTube Channel with dozens of videos on topics relevant to dads raising children with special needs - https://www.youtube.com/channel/UCzDFCvQimWNEb158ll6Q4cA/videosPlease support the SFN. Click here to donate: https://21stcenturydads.org/donate/Special Fathers Network: https://21stcenturydads.org/  

We're a couple of folks down this week, so Coleman has put the Game Cupboard signal up, and the man called Rik has answered. Topics include Avowed, revisiting Onimusha: Warlords, and all the gaming news we could get our grubby mitts on. Time Stamps 00:00:00 Start 00:00:09 Intro 00:00:52 Check out Game Cupboard on YouTube 00:01:57 Gregory Horror Show 00:03:24 Samurai Pizza Cats: Blast from the Past! 00:04:59 Onimusha: Warlords 00:13:21 Avowed 00:25:17 Pokémon Presents Event Set for February 27 00:30:04 Niantic Reportedly in Talks to Sell Game Division 00:36:27 Ubisoft Unveils Siege X 00:38:51 Team17 Joins GOSH Charity Sale: Play It. Build It. Beat It. 00:41:11 Check out our merch at TeePublic.com/stores/BRB 00:42:17 Tabletop Tuesday at Loading Stoke Newington – 00:44:01 More Rik at Game Cupboard on YouTube 00:45:01 Go to BigRedBarrel.com and Get in Contact with us 00:45:40 I Have a Question… 00:59:15 Outro – Avowed by Venus Theory Thanks for listening to another episode of BRB UK. Here's where you can download this episode's MP3 and subscribe via Apple Podcasts, RSS, Spotify, YouTube, or anywhere else that podcasts are available.

Do mealtimes and discussions around your child's body image leave you feel stressed and frazzled?In this episode of Hello Therapy, I am joined by Clinical Psychologist and author, Dr Anna Colton as we discuss how parents can foster healthy attitudes towards food and body image in their children. Anna shares practical tips on spotting early signs of eating disorders and managing weight and body image concerns. We also explore societal pressures, the impact of diet culture, and strategies for making mealtimes positive. Join us for actionable advice to support your child's mental and physical well-being.*Watch an exclusive never heard before mini interview of this episode HERE**Read the Blog HERE*Highlights include:03:46 Addressing Children's Concerns About Body Image06:52 Understanding Diet Culture and Its Impact08:16 Promoting Healthy Eating Habits10:40 Unhelpful Messages Around Food and Body Image18:30 Challenges with School's Approach to Food Education21:09 Addressing Parental Body Image Concerns22:46 Practical Tips for Parents25:10 Making Veggies Fun for Kids27:29 Spotting Eating Disorders in Teens31:21 Gym Culture and Its Impact on Teens35:40 Key Takeaways for ParentsThis week's guestDr Anna Colton is a clinical psychologist and has specialised in eating disorders and adolescence for over 20 years. She spent 10 years in the NHS, working at Great Ormond Street Hospital and in other eating disorder services and units, before moving to private practice. Anna is a huge believer in prevention where possible and otherwise in early intervention. In addition to her eating disorder and adolescent specialties, she now has a diverse range of niches which include media work, both on screen and radio as an ‘expert' and behind the scenes assessing and supporting contributors in reality TV shows and documentaries; working in the West End with 'child stars', and adults with stage fright and performance issues and with barristers and the Bar more widely.Follow Anna:@drannacoltonBuy her book, How to Talk to Children About Food:UK/e-book,Kindle New ZealandAustraliaBE PART OF OUR GROWING SUBSTACK COMMUNITY FOR FREE - Join now****************For private psychology services and therapy in person (London/Hertfordshire) or online, please visit Harley Clinical Psychology.*****************Subscribe to Dr Liz's YouTube channelFollow Harley Clinical on InstagramFollow Dr Liz White on TikTok*****************DISCLAIMER - The Hello Therapy podcast and the information provided by Dr Liz White (DClinPsy, CPsychol, AFBPsS, CSci, HCPC reg.), is solely intended for informational and educational purposes and does not constitute personalised advice. Please reach out to your GP or a mental health professional if you need support.

In the heart of London, a quiet revolution is underway, one that is set to transform the way we experience our urban environments. At the forefront of this movement is Scott Carroll and LDA Design, landscape architects whose visionary projects are redefining the relationship between people and nature. Their work at Great Ormond Street Hospital, a renowned children's medical facility, is a prime example of how biophilic design can heal the wounds of the built environment."Great Ormond Street Hospital, in common with many of London's hospitals, faces massive challenges in the streets and spaces around it," Scott explains. "It's a vehicle-dominated environment, lacking in high-quality space for people and nature." The consequences are dire, with air pollution levels exceeding World Health Organization recommendations and a severe shortage of green spaces for the hospital community and local residents. But Scott and his team have a bold vision. By reclaiming vehicle space and introducing a rich, curated planted environment, they aim to create the UK's first "healthy hospital street." This pioneering approach will not only reduce harmful emissions but also provide a sensory oasis for patients, staff, and visitors alike. "We're applying biophilic design through patterns and design opportunities," Scott says. "The first layer is about creating prospect and refuge, exploration, and discovery. The second is about introducing natural sensory content, primarily through a carefully curated planted environment." The transformative impact of this project is not lost on Scott. "When you think about the impact we have and the people that we reach, this is such a fantastic opportunity to put biophilic benefits and outcomes right at the heart of people's experience," he says. But Great Ormond Street is just one piece of Scott's ambitious portfolio. Across the city, at the East Bank Stratford Waterfront development, they are leading the design of a new cultural and educational district that seamlessly blends people, culture, and nature."It's a really unique blend," Scott enthuses. "You'll see groups of school children sat on the terraces, working like an outdoor classroom, learning about the park and the environment. And then you'll have the first event that Sadler's Wells put on, with hip-hop dancers on the same terraces." As the project slowly unfolds, Scott finds himself increasingly inspired by the transformative power of biophilic design. "Every time I go there, there's something new that I see that I just find inspirational," he says. In a world increasingly dominated by concrete and steel, Scott's work stands as a testament to the healing power of nature. By weaving biophilic principles into the fabric of our cities, he is not only improving physical and mental well-being but also fostering a deeper connection between people and the natural world. https://www.lda-design.co.uk Great Ormond Street Hospital and LDA Design, Reimagining Great Ormond Street won the award for Health and Place at the Thornton Education Trust Inspire Future Generations Awards https://www.thorntoneducationtrust.org/ifgawards2024winnersandcommendations Have you got a copy of the Journal? You can now subscribe and become a member of our Biophilic Design Network or purchase a copy directly from us at the journalofbiophilicdesign.com or Amazon. If you like our podcast and would like to support us in some way, you can buy us a coffee if you'd like to, thank you x Did you miss the Biophilic Design Conference? Did you know you can buy a catch up ticket here and watch anytime you like on demand? www.biophilicdesignconference.com Credits: with thanks to George Harvey Audio Production for the calming biophilic soundscape that backs all our podcasts. Did you know our podcast is also on Audible, Amazon Music, Spotify, iTunes, YouTube, Stitcher, vurbl, podbay, podtail, and most if not all the RSS feeds?Facebook https://www.facebook.com/journalofbiophilicdesign/Twitter https://twitter.com/JofBiophilicDsnLinkedIn. https://www.linkedin.com/company/journalofbiophilicdesign/Instagram https://www.instagram.com/journalofbiophilicdesign

Dr Jane Gilmour talks about the new ACAMH series 'Inside the Teen Brain'. Jane is a Consultant Clinical Psychologist (Hon) at Great Ormond Street Hospital, and Course Director for postgraduate child development programmes at University College London, where she lectures on neuropsychology, neurodevelopmental conditions (Tourette's syndrome, autism, OCD) and therapeutic issues. She has published numerous academic articles and chapters on these topics. Her media presence, commenting on young people's well-being, includes appearances on BBC TV, BBC radio and broadsheet press commissions. How to Have Incredible Conversations with your Child (co-authored with Dr Bettina Hohnen) is her latest book. Using an innovative format, families use the book together in a shared experience to strengthen communication skills and their relationship. She wrote (with co-authors Dr Bettina Hohnen and Dr Tara Murphy), best-seller The Incredible Teenage Brain Book (Everything You Need to Know to Unlock Your Teen's Potential) which has been translated into numerous languages.

While paediatric onset multiple sclerosis is relatively rare, it presents unique challenges. Extensive research efforts are taking place around the world to better understand the disease mechanism of paediatric MS and the similarities and differences that exist with adult onset MS to help determine the best treatment options for children and adolescents. In this episode, host Brett Drummond of MSTranslate explores the topic with Dr. Yael Hacohen of Great Ormond Street Hospital for Children and UCL Institute of Neurology in the UK and Dr. Thaís Armangué of SJD Barcelona Children's Hospital in Spain.

In this World Antimicrobial Resistance Awareness Week episode, Neha Voralia shares her journey from community pharmacy to becoming an advanced anti-infectives pharmacist.  Starting at Northampton General Hospital, she discovered her passion for antimicrobial stewardship through working with complex diabetic foot infections and surgical patients. Neha discusses her transition to paediatric antimicrobial stewardship at Great Ormond Street Hospital, highlighting the unique challenges of managing resistant infections in children, from dosing complexities to medication adherence. Now working at Buckinghamshire NHS Trust, she reflects on the evolving nature of antimicrobial pharmacy and her aspirations in infectious diseases. KEY TAKEAWAYS: Antimicrobial stewardship requires extensive knowledge of bacteria, resistance patterns, and complex patient factors. Paediatric antimicrobial management presents unique challenges, from dose calculations to medication adherence strategies. The role extends beyond clinical work to include guideline development, infection prevention, and regional collaboration. Tertiary centers manage particularly complex cases where standard guidelines may not apply. Professional development opportunities in antimicrobial stewardship include research, conference presentations, and global health initiatives. HAVE YOU EVER THOUGHT ABOUT LIFE OUTSIDE THE TRADITIONAL 9-5? Are you a pharmacist dreaming of: - Working on your own terms? - Achieving location independence? - Building financial freedom? I've been there. That's why I'm sharing my journey from traditional 9-5 pharmacist to creating a life of freedom and fulfillment. In this weekly newsletter, I'll be opening up about my transition to unconventional pharmacy, practical tips for working on your own terms, strategies for financial independence, and our family's adventures in homeschooling and world travel. Ready to reimagine what's possible in your pharmacy career and life? Sign up

For this very special episode we've been working with Great Ormond Street Hospital Charity, which is currently in the middle of its biggest-ever fundraising appeal to build a world-leading cancer centre at Great Ormond Street Hospital.And no-one understands the significance of this appeal more than this week's amazing guest Shaima, whose daughter Tia was diagnosed with a rare type of cancer when she was just 4 years old. Tia is now 12 and doing well at home, but has spent over half of her life in hospital.Shaima sits down with Gi for a very candid conversation about her journey with Tia's cancer treatment and why places like Great Ormond Street Hospital need our support.Trigger warning: this episode contains discussions about cancer. If you feel this may be a difficult listen, please choose another episode. Hosted on Acast. See acast.com/privacy for more information.

Ananda Developments Finance Director Jeremy Sturgess-Smith joined Steve Darling from Proactive to announce significant advancements for the company. Two of Ananda's patent-pending cannabinoid medicines, MRX2 and MRX2T, will be used in two Phase IIIa epilepsy clinical trials, co-funded by the National Institute for Health and Care Research (NIHR) and the NHS. The trials, conducted by investigators at University College London and Great Ormond Street Hospital, will involve up to 500 patients and represent the world's first double-blind randomized controlled trials to investigate the combined use of cannabidiol (CBD) and tetrahydrocannabinol (THC) for epilepsy. These will also be the first to evaluate such treatments for both children and adults with difficult-to-treat epilepsies. Sturgess shared that the MRX formulations will serve as the investigational medicinal products for these ground-breaking trials, which aim to support a marketing authorization application for MRX2 and MRX2T. Should the trials yield positive results, Ananda plans to advance further regulatory and commercial development activities for these medicines. The trials will assess the safety and efficacy of the specific cannabidiol and CBD plus THC formulations in patients suffering from two forms of treatment-resistant epilepsy. Favorable results could pave the way for submission to the UK's Medicines and Healthcare products Regulatory Agency (MHRA) and other regulatory bodies, moving Ananda one step closer to introducing innovative cannabinoid treatments for epilepsy. #proactiveinvestors #anandadevelopmentsplc #aqse #ana #EpilepsyResearch #CannabinoidMedicine #ClinicalTrials #CBDTherapy #PharmaInnovation #NIHR #Healthcare #EpilepsyTreatment#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Welcome to the 22nd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with senior author Dr Torsten Baldeweg of the Brain article entitled: Long-term neuropsychological trajectories in children with epilepsy: does surgery halt decline? Dr Baldeweg discusses fascinating insight into the long term cognitive outcomes from an impressively large cohort of 500 children who had undergone epilepsy surgery and neuropsychological assessment at Great Ormond Street Hospital (1990–2018). Their findings suggest that there are long term cognitive benefits from epilepsy surgery by preventing firther seizures. This has important clinical implications on the importance of achieving seizure freedom for our patients and the role of surgery in this regard. The Brain podcast team is very happy to introduce a new co-host Dr Roberto Bellanti in this episode and to the team! Check out the full article on the Brain website as part of the August 2024 issue: https://doi.org/10.1093/brain/awae121 This episode was co-hosted by Michael David and Roberto Bellanti,  edited and produced by Chaitra and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

What better way to celebrate women's health this month than to introduce Marlene Ellmer of Vergelegen Dietitians, who is our guest on #BusinessLunchWithCoachLindie today!   After graduating with a master's degree in nutrition, Marlene spent time in the United Kingdom, mainly specialising in gut disorders and paediatrics. She also worked at the world-renowned Great Ormond Street Hospital for Children in London.   Marlene has been in private practice for over ten years and sees a variety of patients at the practice as well as virtually. She recently embarked on the journey of nutrigenomics and nutrigenetics and educated herself on the impact of genetics on nutrition, health and disease.

How do you handle setbacks and challenges? Do you struggle, or do you stay afloat? Cathleen sits down with Russell Harvey, known widely as the resilience coach. With a career spanning over two decades in learning and development, Russell brings a wealth of experience and personal anecdotes that illustrate the profound impact of balancing humanity, data, and processes within organisations. Tune in to explore the essential components of resilience, strategies to adapt in a VUCA (Volatile, Uncertain, Complex, Ambiguous) world, and the importance of building a robust support network. Get ready to embrace change and discover the keys to thriving through adversity with actionable advice and heartfelt stories that will inspire you to become a legendary leader.   Episode Timeline:  01:07 Handling setbacks and understanding resilience as a tool. 09:13 Leadership involves resolving dilemmas ethically, creatively and adaptably. 11:50 Resilience is springing forward with learning, not bouncing back. 27:33 Adaptability is openness to change, not action. 39:35 Repeated experiences taught self-care and practical tasks. 48:16 Personal challenges taught resilience. 56:51 Leaders need training on managing emotions during change. 01:03:38 Team gathers situational awareness through conversations.   Key Takeaways:  Russell emphasises fostering a supportive community and maintaining continual communication are crucial for organisational resilience. Leaders must consider emotional intelligence and open dialogue to manage their teams and create a resilient culture effectively. According to Russell, resilience encompasses multiple components: attitude, purpose, confidence, adaptability, support network, meaning, and energy. Resilience involves a combination of being open to change, maintaining a positive attitude, and leveraging one's support network for energy and strength.  Both Cathleen and Russell discuss the importance of adaptability and agility, especially in the face of Volatility, Uncertainty, Complexity, and Ambiguity (VUCA). Leaders need to be proactive in their decision-making, maintaining situational awareness and clarity amidst change.   ABOUT Russell Harvey: Russell Harvey, "The Resilience Coach", is a dynamic and engaging Leadership Coach and Facilitator, Public Speaker, Managing Director, NED, Podcaster, and Radio Host. With over 20 years of experience in Learning, Leadership, and Organizational Development, Russell has specialised in Resilience and VUCA for the past 18 years. Russell's areas of specialisation include Resilience in our modern world of uncertainty and ambiguity, executive coaching and leadership development, talent management and career coaching, facilitation, change leadership, and creativity. He has worked with a wide range of clients, including NHS, BT, The Co-operative Group and Bank, WM Morrisons, Great Ormond Street Hospital, and many more.   Connect with Russell: Website: https://www.theresiliencecoach.co.uk/   Social Media Links: Facebook:https://www.facebook.com/theresiliencecoach/ LinkedIn: http://www.linkedin.com/in/russelltheresiliencecoach Connect: 
  Find | Cathleen O'Sullivan  Business: cathleenmerkel.com   Email: cmc@cathleenmerkelcoaching.com  LinkedIn: https://www.linkedin.com/in/cathleen-merkel/ Instagram: https://www.instagram.com/legendary_leaders_cathleenos/     FOLLOW LEGENDARY LEADERS ON APPLE, SPOTIFY OR WHEREVER YOU LISTEN TO YOUR PODCASTS.  

Great Ormond Street Hospital in London has launched an urgent review of 721 cases that were treated by a former surgeon. The hospital has revealed multiple children had come to severe harm under the care of Yaser Jabbar, a consultant orthopaedic surgeon. UK correspondent Gavin Grey says it's alleged Jabbar conducted inappropriate procedures on these children - causing permanent damage in some.  LISTEN ABOVESee omnystudio.com/listener for privacy information.

Tammy Lovell is joined by Victoria Betton, director at Peopledotcom and Hassan Chaudhury, commercial director at DATA-CAN, to talk about how to overcome racism and discrimination in the digital health sector. Along with NHS doctor Ayesha Rahim, Betton and Chaudhury are founders behind the creation of an Equity Charter, which aims to put anti-racism guiding principles for the sector in place. In the podcast, they discuss how the idea for the charter was formed at Digital Health Rewired in March 2024, following racist remarks made by TPP founder Frank Hestor, reported in The Guardian. This led Rahim, Betton and Chaudhury to publish an open letter online condemning racism and discrimination in digital health, which has had more than 1,000 signatories. In July 2024, the three founders held a summit at The King's Fund in London, attended by around 30 stakeholders, to discuss what should be included in an Equity Charter. In the podcast, the pair discuss how the views expressed by NHS suppliers can affect patient care and what needs to happen to make sure that everyone in the supply chain adheres to equality, diversity and inclusion policies. Chaudhury also highlights how anti-racism in digital health goes further than procurement, and why some NHS organisations and employees are choosing to leave X because it no longer aligns with their values. You can find out more about the Equity Charter and sign here. Guests: Victoria Betton, director at Peopledotcom Hassan Chaudhury, commercial director at DATA-CAN and head of commercial at Great Ormond Street Hospital for Children NHS Foundation Trust  

The National Institute for Health and Care Excellence has, for the first time, published a guideline on the identification and management of adrenal insufficiency, a rare condition which occurs when the adrenal glands do not produce enough essential hormones – particularly cortisol and aldosterone. We're joined by Dr Helen Simpson, a consultant endocrinologist at UCLH NHS Foundation Trust and Sally Tollerfield an endocrine clinical nurse specialist at Great Ormond Street Hospital, to discuss the guideline and the benefits it will provide to patients and healthcare professionals.

Get your 3 months FREE Beauty Pie Membership HEREThis week we are joined by Ciara McClarey, Advanced Clinical Physiotherapist specialising in paediatric physiotherapy and mum of twins! In this episode, Ciara talks about the most common concerns that she sees from families from her work in clinic and her private practice, gives valuable tips and advice on at-home activities to help with your child's physical development, when to seek professional help for concerns, tummy time advice and so much more! This episode has so many takeaways and offers so much wisdom from Ciara on all things physio for children!Ciara has 14 years clinical physiotherapy experience working in a range of Paediatric settings including working at the world renowned Great Ormond Street Hospital. Ciara has developed specialist skills in Baby and toddler assessment and gross motor development, child and adolescent injury prevention and management, strength training in children and adolescents, management of Rheumatological conditions, and the assessment and treatment of infant orthopaedic conditions including Pavlik harness management for hip dysplasia, and Ponseti management of clubfoot. In 2021 she completed a Masters in Advanced Clinical Practice specialising in Paediatric Musculoskeletal rehabilitation, gaining a Distinction. This added Orthopaedic triage, musculoskeletal imaging requests and interpretation, and rehabilitation of national sports teams to her repertoire of skills. Ciara also works in the NHS as an Advanced Practice Paediatric Musculoskeletal Physiotherapist alongside Orthopaedic Consultants and Paediatricians.Ciara has always been passionate about Paediatric Physiotherapy and helping children in pain return to play and sports in a safe and enjoyable environment that reduces the chance of re-injury. She follows the ethos that “Children are not just little adults” and that they require specialist assessment and skills to appropriately treat and manage conditions of a growing skeletal system. Ciara is passionate about evidence based practice and the development of paediatric physiotherapy and is an active member of the Association of Paediatric Chartered Physiotherapist's (APCP) London and National Committees and helps to produce webinars and research to promote and raise awareness of this specialist area.As a parent to young twins, she understands the importance of a holistic approach to therapy that works for the child's wellbeing and with family life. Ciara is passionate about spreading the awareness of baby, child and teenage physiotherapy and top tips for parents and families to nurture healthy active futures.Connect with Ciara HEREConnect with the Carol App HEREDownload the free Carol App for Mums on iOS and Android!Submit your questions to the podcast HERE & start your question with the word 'PODCAST'. We can't wait to hear from you! Hosted on Acast. See acast.com/privacy for more information.

Episode 27 : The Ghostbusters Immersive Experience Thank you for joining us on the Ghostheads UK Podcast, your ultimate destination for all things Ghostbusters in the heart of Yorkshire!.  In the show today, Am Joined by Fern Sherrat-Wells and Fern is hosting an Ghostbusters Immersive Experience event with all money going to the Great Ormond Street Hospital, so please join us  Connect with us across social media to stay in the loop. Search for @ghostheadsuk on Facebook, Twitter, Instagram, and YouTube. Don't forget to hit that like button, subscribe, and turn on notifications to catch all our thrilling episodes, discussions, and exciting updates. Got something to share about Ghosts or Ghostbusters?, Want to get on next month's roll call?, We'd love to hear from you! Drop us an email at GhostheadsUK@gmail.com Let's engage in captivating conversations and delve deeper into the realms of the supernatural,  Thank you for being part of the Ghostheads UK Podcast community.  00:00 Ghostheads intro 02:15 Ghostheads Rolecall 05:16 Fern Sherrat-Wells 90:30 End of the show  Thank you for tuning into the show, Stay curious, Stay Spooky, and Keep Busting Ghostheads  Many Thanks.. Fern Looking for Ghostbusting Equipment then head over to lease links https://www.8th-logistics.com/product-page/red-parka https://www.facebook.com/Sparkys-propshop-946967075428363/ http://www.facebook.com/keymasterprops/ http://www.facebook.com/blindwolfcosplay/ http://www.facebook.com/benofkentprops/ http://www.facebook.com/cle3dprints/ https://www.8th-logistics.com/product-page/red-parka  Ghostheads Uk Tee public Store https://www.teepublic.com/en-gb/user/sirjedijamie50101  Cameo: Ernie Hudson https://www.cameo.com/5c9537322cf0090146f04455  Ghostbusters News https://ghostbustersnews.com/

Right now, in hospitals around the world, patients are being cured of diseases once thought untreatable. The reason? A gene therapy revolution means that what was once the stuff of science fiction is now becoming a reality. One person who's been at the centre of this medical revolution is Dr Bobby Gaspar, a professor of paediatrics and immunology at Great Ormond Street Hospital and University College London, and CEO of Orchard Therapeutics. Bobby guides us through the complex world of gene therapy, explaining what it is, what it can do and where it's going. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Every year, the European Healthcare Design Conference brings together professionals from all over the world involved in design and healthcare to share unique projects, solutions, and concepts. It's all about creating better healthcare spaces and experiences for patients and clinicians.Sunand Prasad is the programme director of European Healthcare Design and the architect and Principal of the global architecture and design firm Perkins and Will. As new technologies are becoming common in our daily lives, he shares his thoughts on what is required of us to ensure we don't repeat the same mistake in healthcare.Dr Paul Barach is an Anaesthetist, Critical Care Physician-Scientist, public health researcher and senior lecturer at Thomas Jefferson University in Philadelphia. He shares his thoughts on burnout and poor staff retention and why talking about these things at a design conference is essential.Gareth Drake is a Clinical Psychologist at Great Ormond Street Hospital, working predominantly with the clinical staff there. Gareth shares why we need dedicated spaces for private conversation and emotional processing in hospitals as clinicians and patients.Connect with Rolake Ojo:LinkedInInstagramWebsiteCheck out &MATTER:LinkedInInstagramResourcesLearn more about European Healthcare Design CongressLearn more about Sunand Prasad, OBELearn more about Paul Barach Learn more about Gareth DrakeBrand New Dr. is produced and managed by Urban Podcasts.

A mum from Deal has hit out at a London hospital after receiving a letter booking her son in for an appointment - more than a year after he died.Imogen Holliday was sent an email inviting three-year-old Raffy for a visit to Great Ormond Street exactly 14 months after he'd passed away there.Also in today's podcast, a leading Kent charity is calling on whoever forms the next government to ban so-called no-fault evictions.It was part of the renters reform bill that was going through parliament before the election was called. We've been speaking to Canterbury based Porchlight.A business owner in Rainham says a new red route along the high street is turning customers away.The introduction of the double red lines along the A2 was meant to help enforce existing traffic restrictions and tackle congestion. Find out what one trader's had to say and the response from the local council.A Kent veteran who landed on the beaches of Normandy on D Day is returning there this week to mark the 80th anniversary.Peter Smoothy from Herne Bay was one of 156,000 allied servicemen who took part in the invasion. He'll travel to Normandy thanks to the Taxi Charity which is run by London black cab drivers. Hear from Micky Harris from Longfield who's one of them.And in sport, it was a mixed weekend for Kent after two games in the T20 Blast.The Spitfires beat Middlesex away from home on Friday night, but lost to Hampshire Hawks yesterday.

So you've built your first terrarium. What's next? Water and light are the key aspects you'll need to keep an eye on. Then you can add plants if you're feeding detritivores. Using the proper tools will make maintenance much easier too!Epic Gardening Shop Homepage: https://growepic.co/3yzFMarBotanical Interests Shop Homepage: https://growepic.co/4bQ9ru7Book Collection Page: https://growepic.co/4bSaBFuEG Homesteading Book: https://growepic.co/3wNGal0Learn More: How to Make a Terrarium: A Step-by-Step GuideConnect With Ben Newell:Ben is the founder of Worcester Terrariums, with over 3.5 million followers across his social platforms. His journey from overcoming personal challenges to discovering his passion for horticulture has not only won him a gold medal at the Chelsea Flower Show but also paved the way for successful partnerships with giants like Disney, Marvel, Biorb, Great Ormond Street Hospital and Paramount. Ben's first book, Hello Tiny World with DK Books, is set to be released in May 2024.WebsiteInstagramYouTubeTikTokFacebookLove Epic Gardening products?Apply to the Epic Affiliate Program. Shop the StoreAs an exclusive for listeners, use code THEBEET for 5% off your entire order on our store, featuring our flagship Birdies Raised Beds. These are the original metal raised beds, lasting up to 5-10x longer than wooden beds, are ethically made in Australia, and have a customizable modular design. Get Our BooksLooking for a beginner's guide to growing food in small spaces? Kevin's book, Field Guide to Urban Gardening, explains the core, essential information that you'll need to grow plants, no matter where you live!He also wrote Grow Bag Gardening to provide you with specialized knowledge that can bring you success when growing in fabric pots.Preorder Kevin's newest book Epic Homesteading if you are looking to turn your home into a thriving homestead! Order signed copies of Kevin's books, plus more of his favorite titles in our store.More ResourcesLooking for more information? Follow us:Our BlogYouTube (Including The Beet Podcast,  Epic Homesteading and Jacques in the Garden and Botanical Interest )Instagram (Including Epic Homesteading, Jacques)PinterestTikTokFacebookFacebook GroupDiscord Server

If you want to add animals to your first terrarium, it might be difficult to know where to start. You need to know animal food sources, and what size of container is suitable to which species. Thankfully, Ben Newell has the skinny on what you need for housing animals in your terrarium.Epic Gardening Shop Homepage: https://growepic.co/3QTzcSbBotanical Interests Shop Homepage: https://growepic.co/4bvRNwaBook Collection Page: https://growepic.co/3VaM1KCEG Homesteading Book: https://growepic.co/4dUUZ68Learn More: How to Make a Terrarium: A Step-by-Step GuideConnect With Ben Newell:Ben is the founder of Worcester Terrariums, with over 3.5 million followers across his social platforms. His journey from overcoming personal challenges to discovering his passion for horticulture has not only won him a gold medal at the Chelsea Flower Show but also paved the way for successful partnerships with giants like Disney, Marvel, Biorb, Great Ormond Street Hospital and Paramount. Ben's first book, Hello Tiny World with DK Books, is set to be released in May 2024.WebsiteInstagramYouTubeTikTokFacebookLove Epic Gardening products?Apply to the Epic Affiliate Program. Shop the StoreAs an exclusive for listeners, use code THEBEET for 5% off your entire order on our store, featuring our flagship Birdies Raised Beds. These are the original metal raised beds, lasting up to 5-10x longer than wooden beds, are ethically made in Australia, and have a customizable modular design. Get Our BooksLooking for a beginner's guide to growing food in small spaces? Kevin's book, Field Guide to Urban Gardening, explains the core, essential information that you'll need to grow plants, no matter where you live!He also wrote Grow Bag Gardening to provide you with specialized knowledge that can bring you success when growing in fabric pots.Preorder Kevin's newest book Epic Homesteading if you are looking to turn your home into a thriving homestead! Order signed copies of Kevin's books, plus more of his favorite titles in our store.More ResourcesLooking for more information? Follow us:Our BlogYouTube (Including The Beet Podcast,  Epic Homesteading and Jacques in the Garden and Botanical Interest )Instagram (Including Epic Homesteading, Jacques)PinterestTikTokFacebookFacebook GroupDiscord Server

Ben Newell of Worcester Terrariums has all the info you need about building your own terrarium at home. From containers, to soil, and even to different ways to build your own, there is much that goes into it. But it only has to be as expensive or exotic as you want it to be.Epic Gardening Shop Homepage: https://growepic.co/3KhCefmBotanical Interests Shop Homepage: https://growepic.co/3VcC1jQBook Collection Page: https://growepic.co/4dWm7BuEG Homesteading Book: https://growepic.co/3KhfOLwLearn More: How to Make a Terrarium: A Step-by-Step GuideConnect With Ben Newell:Ben is the founder of Worcester Terrariums, with over 3.5 million followers across his social platforms. His journey from overcoming personal challenges to discovering his passion for horticulture has not only won him a gold medal at the Chelsea Flower Show but also paved the way for successful partnerships with giants like Disney, Marvel, Biorb, Great Ormond Street Hospital and Paramount. Ben's first book, Hello Tiny World with DK Books, is set to be released in May 2024.WebsiteInstagramYouTubeTikTokFacebookLove Epic Gardening products?Apply to the Epic Affiliate Program. Shop the StoreAs an exclusive for listeners, use code THEBEET for 5% off your entire order on our store, featuring our flagship Birdies Raised Beds. These are the original metal raised beds, lasting up to 5-10x longer than wooden beds, are ethically made in Australia, and have a customizable modular design. Get Our BooksLooking for a beginner's guide to growing food in small spaces? Kevin's book, Field Guide to Urban Gardening, explains the core, essential information that you'll need to grow plants, no matter where you live!He also wrote Grow Bag Gardening to provide you with specialized knowledge that can bring you success when growing in fabric pots.Preorder Kevin's newest book Epic Homesteading if you are looking to turn your home into a thriving homestead! Order signed copies of Kevin's books, plus more of his favorite titles in our store.More ResourcesLooking for more information? Follow us:Our BlogYouTube (Including The Beet Podcast,  Epic Homesteading and Jacques in the Garden and Botanical Interest )Instagram (Including Epic Homesteading, Jacques)PinterestTikTokFacebookFacebook GroupDiscord Server

Here, Kevin and Ben Newell discuss the different ways you can jazz up your terrarium, diving into the complexities of adding isopods. They touch on different ways people make their terrariums unique and interesting, and how you can do the same. Epic Gardening Shop Homepage: https://growepic.co/4dWiUSOBotanical Interests Shop Homepage: https://growepic.co/3VcmFvLBook Collection Page:  https://growepic.co/3wMcXqIEG Homesteading Book: https://growepic.co/3KfHzUwLearn More: How to Make a Terrarium: A Step-by-Step GuideConnect With Ben Newell:Ben is the founder of Worcester Terrariums, with over 3.5 million followers across his social platforms. His journey from overcoming personal challenges to discovering his passion for horticulture has not only won him a gold medal at the Chelsea Flower Show but also paved the way for successful partnerships with giants like Disney, Marvel, Biorb, Great Ormond Street Hospital and Paramount. Ben's first book, Hello Tiny World with DK Books, is set to be released in May 2024.WebsiteInstagramYouTubeTikTokFacebookLove Epic Gardening products?Apply to the Epic Affiliate Program. Shop the StoreAs an exclusive for listeners, use code THEBEET for 5% off your entire order on our store, featuring our flagship Birdies Raised Beds. These are the original metal raised beds, lasting up to 5-10x longer than wooden beds, are ethically made in Australia, and have a customizable modular design. Get Our BooksLooking for a beginner's guide to growing food in small spaces? Kevin's book, Field Guide to Urban Gardening, explains the core, essential information that you'll need to grow plants, no matter where you live!He also wrote Grow Bag Gardening to provide you with specialized knowledge that can bring you success when growing in fabric pots.Preorder Kevin's newest book Epic Homesteading if you are looking to turn your home into a thriving homestead! Order signed copies of Kevin's books, plus more of his favorite titles in our store.More ResourcesLooking for more information? Follow us:Our BlogYouTube (Including The Beet Podcast,  Epic Homesteading and Jacques in the Garden and Botanical Interest )Instagram (Including Epic Homesteading, Jacques)PinterestTikTokFacebookFacebook GroupDiscord Server

Ben's interest in plants and terrariums came later in life, in his 20s. He sought out many different horticultural hobbies, and terrariums are the interest he stuck with. His love for the simplicity of terrariums led to his founding of Worcester Terrariums, which has amassed millions of followers.Epic Gardening Shop Homepage: https://growepic.co/4bSa5HyBotanical Interests Shop Homepage: https://growepic.co/44VLCyUBook Collection Page:  https://growepic.co/3Kh1cvGEG Homesteading Book: https://growepic.co/3KhfBIeLearn More: How to Make a Terrarium: A Step-by-Step GuideConnect With Ben Newell:Ben is the founder of Worcester Terrariums, with over 3.5 million followers across his social platforms. His journey from overcoming personal challenges to discovering his passion for horticulture has not only won him a gold medal at the Chelsea Flower Show but also paved the way for successful partnerships with giants like Disney, Marvel, Biorb, Great Ormond Street Hospital and Paramount. Ben's first book, Hello Tiny World with DK Books, is set to be released in May 2024.WebsiteInstagramYouTubeTikTokFacebookLove Epic Gardening products?Apply to the Epic Affiliate Program. Shop the StoreAs an exclusive for listeners, use code THEBEET for 5% off your entire order on our store, featuring our flagship Birdies Raised Beds. These are the original metal raised beds, lasting up to 5-10x longer than wooden beds, are ethically made in Australia, and have a customizable modular design. Get Our BooksLooking for a beginner's guide to growing food in small spaces? Kevin's book, Field Guide to Urban Gardening, explains the core, essential information that you'll need to grow plants, no matter where you live!He also wrote Grow Bag Gardening to provide you with specialized knowledge that can bring you success when growing in fabric pots.Preorder Kevin's newest book Epic Homesteading if you are looking to turn your home into a thriving homestead! Order signed copies of Kevin's books, plus more of his favorite titles in our store.More ResourcesLooking for more information? Follow us:Our BlogYouTube (Including The Beet Podcast,  Epic Homesteading and Jacques in the Garden and Botanical Interest )Instagram (Including Epic Homesteading, Jacques)PinterestTikTokFacebookFacebook GroupDiscord Server

Dr Ghassan Abu-Sittah is no stranger to conflict zones, having  spent decades volunteering for medical charities in Palestine, Lebanon, Yemen, Syria, and Iraq. But the plastic and reconstructive surgeon says his latest experience in Gaza has no parallel. The scale of the current suffering in Gaza, “the intensity, the ferocity, the viciousness, and the deliberate targeting of the hospitals”, he says, was like "a tsunami”.Dr Abu-Sittah travelled to Gaza days after Israel began its bombardment in response to the October 7 attack by Hamas. He remained in the besieged enclave for 43 days, working mainly in northern Gaza as a volunteer for Médecins Sans Frontières (MSF).He was at Al-Ahli Hospital during the massacre on October 17, 2023, and was among the physicians who spoke to news media, surrounded by blood-stained bodies, in the attack's immediate aftermath. He later gave evidence to the International Court of Justice (ICJ) at The Hague about what he saw.In this moving interview with Maysa Jalbout, Dr Abu-Sittah shares his experiences of working in Gaza and what it was like knowing his wife and children were watching him caught up in the attacks in real time on social media.Since returning home to the UK, he has announced plans to set up The Ghassan Abu Sittah Children's Fund to pay for injured Palestinians to receive medical and rehabilitation treatment in Lebanon.Children have borne the brunt of this latest chapter of conflict in Palestine. Before October 7, there were nearly 200 war-related amputations among young people in Gaza as well as some 2,000 adults living with amputations from earlier conflicts. Dr Abu Sittah says there could now be as many as 5,000 child amputees, with many losing limbs due to an inability to treat what would ordinarily be very salvageable injuries.Children with amputations need new prosthetics every six to eight months as they grow and could require as many as 12 surgeries before they reach adulthood, he explained. In addition to the physical impact of their injuries, their mental health needs are also “life altering”. Dr Abu-Sittah was born in Kuwait after his parents were forced from their homes in Palestine in 1948 and became refugees in Gaza. He studied medicine at the University of Glasgow and after completing his Specialist Registrar training in London, he went on to do fellowships  in Paediatric Craniofacial Surgery and  Cleft Surgery at Great Ormond Street Hospital for Sick Kids and then a fellowship in Trauma Reconstruction at the Royal London Hospital. In 2010 he was awarded Fellowship of the Royal College of Surgeons (Plastic Surgery).  Dr Abu-Sittah has served as an associate professor and head of the Division of Plastic and Reconstructive Aesthetic Surgery at the American University of Beirut (AUB) Medical Center,  in 2015, became a founding director of the Conflict Medicine Program at AUB's Global Health Institute, and in March was named Rector of the University of Glasgow.The Impact Room is brought to you by Philanthropy Age and Maysa Jalbout. Find us on social media @PhilanthropyAge

En este nuevo episodio de BackTable, el Dr. Fernando Gómez Muñoz y la Dra. Sara Lojo Lendoiro profundizan en el complejo y específico campo de la radiología intervencionista pediátrica. Al enfatizar las diferencias existentes entre los pacientes adultos y los niños, el Dr. Gómez Muñoz destaca la necesidad de capacitación y enfoques especializados para el manejo de casos pediátricos, especialmente en términos de variantes propias de la edad del paciente como la volemia o el tamaño de los vasos. Se examinan críticamente los desafíos en los procedimientos intervencionistas, particularmente en relación con las complejidades propias del trabajo con pacientes pediátricos y la dificultad añadida de los materiales necesarios. Además, el Dr Gómez Muñoz comparte su trayectoria profesional, su paso por el Great Ormond Street Hospital de Londres y su continuo aprendizaje de colegas de todo el mundo. En el podcast también se explora la necesidad de una colaboración multidisciplinar y se analiza la relación entre los radiólogos intervencionistas y los cirujanos pediátricos. Se subraya la importancia de una comunicación clara con las familias de los pacientes durante procedimientos o diagnósticos particularmente complejos, afirmando que la atención al paciente comienza con el manejo de las emociones y expectativas de los propios médicos. --- SHOW NOTES 00:00 - Introducción a la radiología intervencionista pediátrica 01:27 - Comprender las diferencias entre pacientes adultos y pediátricos 03:08 - Desafíos en radiología intervencionista pediátrica 08:29 - El papel de la formación y la especialización 13:25 - Cómo afrontar las emergencias médicas pediátricas 19:02 - La importancia del enfoque multidisciplinario en la atención pediátrica 26:23 - El futuro de la radiología intervencionista pediátrica 42:44 - Conclusión: La importancia de la radiología intervencionista pediátrica

In episode 2 we welcome Paula Hallam to the Nutshell. Paula is a Paediatric Dietician, founder of ‘Plant Based Kids' and author of the book ‘Plant Powered Little People.' Paula has been a children's dietitian for 25 years, graduating in 1998 from the University of Cape Town and gaining a wide range of experience working in many different settings and hospitals such as Great Ormond Street Hospital and Evelina Children's Hospital London, as well as consulting to charities and providing expert advice to baby food companies. She has also completed a Post Graduate Certificate in Advanced Paediatric Dietetics from the University of Plymouth and in addition, in 2021 she undertook the additional training 'Plant-Based Nutrition: A Sustainable Diet for Optimal Health' at the University of Winchester. Contact Paula: https://plantbased-kids.com Buy Paula's book: https://www.waterstones.com/book/plant-powered-little-people/paula-hallam-rd/9781915538222 Join Paula's webinar on 8th February for free by joining PBHP-UK https://plantbasedhealthprofessionals.com/membership Studies Discussed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157583/ https://www.leapstudy.co.uk/index.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852987/ https://pubmed.ncbi.nlm.nih.gov/28838083/ For our Spanish speaking listeners Miriam Martinez Biarge's book: https://www.amazon.es/familia-vegana-alimentaci%C3%B3n-saludable-equilibrada/dp/8409512394/ref=tmm_pap_swatch_0?_encoding=UTF8&qid=&sr=

It is imperative that children and young people are central to the co-design and co-production of our patient safety improvement interventions. In this episode, we speak with Dr Jane Runnacles, consultant paediatrician at St. George's Hospital, and Dr Victoria Dublon, paediatric diabetes consultant at the Royal Free Hospital. Both are champions of improvement work that puts the young person and their needs first. As Jane and Victoria describe, involving children, young people and their families in improvement work improves the experience and outcome for all involved. There are fantastic examples of co-creating and co-producing safety improvements in healthcare. We discuss the practicalities of how to do this and who to involve in your healthcare setting, and we hear about some of Jane and Victoria's successes. Thank you for listening. Dr Natalie Wyatt, RCPCH Clinical Fellow and Jonathan Bamber RCPCH Head of Quality Improvement  Produced by 18Sixty Please be advised that this podcast series contains stories relating to child death and harm. All views, thoughts and opinions expressed belong to the guests and not necessarily to their employer, linked organisations or RCPCH. Download transcript (PDF)  About the patient safety series As doctors we ‘first, do no harm'. However, the systems in which we work are rife with safety issues and resultant harm. In thinking about how to improve this, we have brought together leaders in the field to discuss challenging and thought-provoking issues around keeping our children safe in healthcare settings. We hope you will be entertained, educated and energised to make strides in improving the safety of the children that you care for. The RCPCH Patient Safety Portal has lots of resources. And our engaging children and young people web pages can help you get started on your engagement journey to effectively work with children and young people to improve their healthcare.  Dr Victoria Dublon is based at the Royal Free Hospital and part of the Trust-wide diabetes team. She has been a paediatric diabetes consultant for eight years, working primarily at the Royal Free Hospital as well as running clinics at Barnet Hospital and Chase Farm Hospital. As a registrar, she trained in adolescent health as well as endocrinology and diabetes and this continues to be a big part of her work. Victoria is involved in improvement work within the department as well as being a champion of ‘Me First', striving to put the young person and their needs first. Dr Jane Runnacles is a consultant in ambulatory paediatrics at St George's hospital NHS Foundation Trust, London and clinical governance lead for her department. She has an interest in acute paediatrics, simulation and quality improvement. During her postgraduate training in London, she was awarded distinction in her MA in clinical education and spent a year as a Darzi clinical leadership fellow at Great Ormond Street Hospital. Jane is a Training Programme Director for the London School of Paediatrics and leads their leadership and QI education programmes. Topics/organisations/papers referenced in this episode Great Ormond Street Hospital Royal Free Hospital Darzi Fellowship Peter Lachman RCPCH SAFE Collaborative RCPCH QI Central Don Berwick Whiteboard communication project (on QI Central) Yincent Tse NHS blog - Asking "What Matters To You?" NHS - Co-production Paediatric Early Warning System (PEWS) St George's Hospital St George's Hospital - Children and Young People's Council Wac Arts WHO World Patient Safety Day (17 September) ‘Listening to you' project at Birmingham Children's Hospital NHS Patient Safety Incident Response Framework Safety huddles (part of Situation Awareness for Everyone)  

William Lau, Assistant Head and Learning Tech Lead at Great Ormond Street Hospital talks about the similarities and differences between mainstream and hospital education, he also extols the virtues of giving admin rights to all staff!

Psychological safety in healthcare settings is the condition in which you feel included, safe to learn, safe to contribute and safe to challenge the status quo - without fear of being embarrassed, marginalised or punished. And it's an essential foundation in building a safety culture. Individually, feeling psychologically safe improves performance and innovation, while feeling unsafe reduces productivity and harms retention. In a highly productive team, it is about feeling safe to take risks, to learn from each other and to feel resilient and able to tackle the difficult and varying challenges of healthcare with a healthy mindset. This is the second episode in our patient safety series and features Dr Dal Hothi and Dr Jess Morgan. Learn how you can reflect on your own behaviour, champion effective communication and create a psychologically safe space within your team. Hosts: Dr Natalie Wyatt, RCPCH Clinical Fellow and Jonathan Bamber, RCPCH Head of Quality Improvement Produced by 18Sixty Please be advised that this podcast series contains stories relating to child death and harm. All views, thoughts and opinions expressed belong to the guests and not necessarily to their employer, linked organisations or RCPCH. If you are a healthcare professional and you are worried that you are suffering with burnout please speak to your team, your GP or Practitioner Health. Download transcript (PDF) About the speakers Dr Dal Hothi is a paediatric nephrologist at Great Ormond Street Hospital. She's also a Director of Leadership Development at the Faculty of Medical Leadership and Management, as well as being an Officer for Lifelong Careers at the RCPCH. Dr Jess Morgan is a paediatric doctor and Dinwoodie RCPCH Fellow who leads on the RCPCH Thrive Paediatrics Project along with Dal. About the patient safety podcast series As doctors we ‘first, do no harm'. However, the systems in which we work are rife with safety issues and resultant harm. In thinking about how to improve this, we have brought together leaders in the field to discuss challenging and thought-provoking issues around keeping our children safe in healthcare settings. We hope you will be entertained, educated, and energised to make strides in improving the safety of the children that you care for. To learn more, visit the RCPCH Patient Safety Portal and begin your journey in improving your own psychological safety and that of those you work with. Links for topics/organisations/papers referenced in this episode Dinwoodie Thrive Paediatrics at RCPCH Amy Edmondson and psychological safety Tim Clark's four stage model of psychological safety Freedom to Speak Up (The National Guardian) Charles Vincent ("Safety is not defined by the absence of negative outcomes") - The Health Foundation: The measurement and monitoring of safety

Healthcare is inherently risky and so as child health professionals we need to make patient safety a priority in all our actions. We need to think about safety all the time.  In episode 1 of our six-part series on paediatric patient safety, we speak with Dr Peter Lachman, who develops and delivers programmes for clinical leaders in quality improvement at the Royal College of Physicians in Dublin. As Peter explains on the podcast, we healthcare professionals need to know patient safety theory - but, more importantly, we need to know how to apply it, drive improvement and create a workplace culture that fosters safe working practices. Everyone - from the most junior member of the team to the most senior paediatric clinical leader - needs to think about patient safety all day every day. A safe culture takes time to build. Shared activities such as handover, huddles and debrief can model good behaviour and benefit performance. Repeating behaviours that represent a safe culture can create a virtuous cycle which can change deeply held attitudes and beliefs, then ultimately the safe culture overall. Thank you for listening. Dr Natalie Wyatt, RCPCH Clinical Fellow and Jonathan Bamber RCPCH Head of Quality Improvement Produced by 18Sixty Please be advised that this series contains stories relating to child death and harm. All views, thoughts and opinions expressed in this podcast series belong to the guests and not necessarily to their employer, linked organisations or RCPCH. Download transcript (PDF) About the Patient safety podcast series As doctors we ‘first, do no harm'. However, the systems in which we work are rife with safety issues and resultant harm. In thinking about how to improve this, we have brought together leaders in the field to discuss challenging and thought-provoking issues around keeping our children safe in healthcare settings. We hope you will be entertained, educated, and energised to make strides in improving the safety of the children that you care for. There are lots of resources that expand on this on the RCPCH Patient Safety Portal, including the theory of patient safety culture and examples of how people across the UK are doing this well. Visit at https://safety.rcpch.ac.uk. More about Dr Peter Lachman Dr Peter Lachman develops and delivers programmes to develop clinical leaders in quality improvement at the Royal College of Physicians in Dublin. He works with HSE Global in Africa, and he was Chief Executive Officer of the International Society for Quality in Healthcare (ISQua) from 1 May 2016 to 30 April 2021. Peter was a Health Foundation Quality Improvement Fellow at IHI in 2005-2006 and then went on to be the Deputy Medical Director with the lead for Patient Safety at Great Ormond Street Hospital 2006-2016. Peter was also a Consultant Paediatrician at the Royal Free Hospital in London specialising in the challenge of long-term conditions for children. Peter is the lead editor of the OUP Handbook on Patient Safety published in April 2022; Co-Editor of the OUP Handbook on Medical Leadership and Management published in December 2022; and Editor of the OUP Handbook on Quality Improvement to be published in 2024. Topics/organisations/papers referenced in this podcast ISQUA (International Society for Quality in Healthcare) Oxford Professional Practice: Handbook Of Patient Safety IHI (Institute for Health Improvement) Human factors - on RCPCH Patient Safety Portal S.A.F.E. Collaborative - on RCPCH Patient Safety Portal Cincinnati Childrens Hospital patient safety Paediatric Early Warning System (NHS England) BMJ Quality & Safety journal Lachman, P., Linkson, L., Evans, T., Clausen, H., & Hothi, D. (2015). Developing person-centred analysis of harm in a paediatric hospital: a quality improvement report. BMJ quality & safety, 24(5), 337–344 Health Foundation A framework for measuring quality, with Professor Charles Vincent et al WellChild: the national charity for sick children Applied human factors - on RCPCH Patient Safety Portal 5 whys SEIPS (Systems Engineering Initiative for Patient Safety) Psychological safety- on RCPCH Patient Safety Portal Situational awareness - on RCPCH Patient Safety Portal MaPSaF (Manchester Patient Safety Awareness Framework) Top Gun Irish Certificate in Essential Leadership for New Consultants Rolfe et al's reflective model (PDF) (what now what so what) NHS England: Improving patient safety - a practical guide

This month we speak to Dr Susie Shelmerdine who is an Academic Paediatric Radiologist at Great Ormond Street Hospital in London. We discuss her niche subspecialty interest, post mortem imaging, and how she has channelled this interest into founding a company called Anubix. We also discuss academia, AI and her recent Radiology outreach trip to Nepal. Enjoy!

As we approach the conclusion of 2023, we reflect on a year that not only signifies our 10-year anniversary but also marks another chapter of The G Word. Throughout the year, guests have joined us fortnightly to share their research, stories, and aspirations for the future of genomic healthcare.  In this special end-of-year episode, Naimah Callachand sits down with Dr Rich Scott, Interim Chief Executive Officer at Genomics England, to look back on the last decade of Genomics England. Tune in as we revisit memorable moments from the 2023 podcast episodes through key quotes, reflecting on the transformative journey of Genomics England. Join us for this insightful recap and a glimpse into the exciting future ahead!  Below are the links to the podcasts mentioned in this episode, in order of appearance:  Adam Rutherford, Laurence Hurst, Cristina Fonseca and Vivienne Parry: Public views on genetics - what have we learnt?  Dr Jack Bartram: Can genomics improve our understanding of childhood cancers?  Helen Webb, Lizzie Mordey, Kirsty Russell and Prabs Arumugam: How can advances in genome sequencing support patients through their sarcoma journey? Vivienne Parry and David Bick: Which conditions will we look for initially in the Generation Study?   Dr Nicola Byrne: What are the challenges of data governance in the digital age?  Chris Wigley: The journey to the Human Genome Project and beyond with Dr Francis Collins   “We're also looking to the future where, as I say, we're proud of the impact that there already has been, and the NHS Genomic Medicine Service is the first national healthcare system to offer whole genome sequencing and that is extraordinary. Thinking about how we can broaden our impact is a really important part of that, and that's thinking about how we can be supportive of genomic technologies broader than just whole genome.”    You can read the transcript below or download it here: Reflecting-on-2023-transcript.docx   Naimah: Welcome to the G Word. Rich: We're in an extraordinary time. The power to analyse genomic data has changed enormously. These are big changes in terms of the, sort of, analytics that AI could bring and the potential to work not just within the UK but with other countries and other big initiatives to make sure that we're answering the questions as best we can. Naimah: I'm your host Naimah Callachand and today we'll be hearing from Rich Scott, Interim CEO for Genomics England. He'll be sharing insights with us from the last year, and we'll be revisiting key moments from earlier podcasts in the year featuring some of the voices that have shaped our discussions. If you enjoyed today's episode we would love your support, please like, share and rate us on wherever you listen to your podcasts. Now let's get into the interview. So, this year we celebrated our ten-year anniversary and as 2023 comes to a close we want to reflect on our achievements not just in the last year but over the last ten. So, Rich first of all can you talk us through where we started in 2013 and where we are now? Rich: It's amazing really to think about how much things have changed in terms of genomics in clinic and in hospitals and then for us as Genomics England over the last ten years. So, actually thinking back ten years ago was only ten years after the Human Genome Project was completed, and when one thinks about what one could do in clinic and those questions you could answer using genomics in clinic. We could see what was coming, we could see these new technologies, next generation sequence in coming, but it was much more dependent on very targeted testing. And now with, you know, our founding project, the 100,000 Genomes Project that Genomics England was founded to deliver in partnership with the NHS we asked the first big question if you like which was how can whole genome sequencing play a role in routine clinical care. And that's now played out where evidence from the project, what we've learnt, the infrastructure we've built, and also evidence from around the world that through the NHS Genomics Medicine Service has now put that into practice and we're working in partnership to help them deliver it. So, it has gone from an idea where we could see this new technology, this potential, to a position where now patients in the NHS with cancer or with rare conditions have whole genome sequencing as a routine part of their clinical care where that's in that national genomic test directory that NHS England have set up. Naimah: Earlier in the year we heard from Dr Adam Rutherford, geneticist, author and broadcaster who commented on how the public perception of genetics and science has evolved over the last few decades. “I've been doing this a long time and I think that when it comes down to it, genetics which is a relatively young science and really in a sophisticated way, you know, a mere few decades old, but what is it at its absolute core, it's thinking about families, it's thinking about inheritance and it's thinking about sex. And these have been the major preoccupations of humans for thousands of years, and it's only really in the last century, really only in the last 30 years or so, that we've had a sophisticated understanding of how these things work, if indeed we have had at all.” Naimah: Let's get back to Rich. Rich, I've already touched briefly on it, but can we dive a bit deeper into the 100,000 Genomes Project and can you tell me a bit more about how it started. Rich: Yes, so the 100,000 Genomes Project as I said was there to ask what role can whole genome sequencing play in understanding medical conditions, you know, is it ready for clinical prime time. And also how can we link routine clinical care to research so that we're not just asking questions with today's knowledge, but we can continue to build that knowledge for the future. So, the 100,000 Genomes Project was driven by that idea that people realising, the government realising and the NHS forming a partnership with us Genomics England to explore that question in real depth. And it's not just about the clinical aspects and the scientific questions, it has also been working with participants and the public to understand how we could do that. And through the 100,000 Genomes Project we worked particularly with patients with cancer and rare conditions to see how we could help make diagnosis and improve care. And also with their consent make their data available in our secure, trusted research environment so that researchers could continue to look for answers that we couldn't answer today, and we continue to do that work for those participants now. Naimah: Next we're going to hear from an interview with Dr Jack Bartram, a Consultant Paediatric Haematologist at Great Ormond Street Hospital for Children. He spoke about the significance and impact of integrating genomics into routine clinical care in diagnosing cancer in children. “If I look back and if I reflect on the last three years, you know, we could probably accurately say at least a quarter of patients it has given us additional information which is either aided in diagnosis or like I had said help risk stratify a patient or potentially reveal a target for a therapy that we didn't know of before. And what this has led to and what we've seen over the last three years or so is that we have actually changed management of patients based on this. So, definitely we've got examples where we scan clarify the diagnosis, we've changed the risk category, or we've identified for example that an unexpected cancer predisposition in a family which has then led onto screening for the family which can then give the family the knowledge to try and do things to either modify the risk of cancer in the family or at least screen for it so they can detect things early to prevent things presenting too late.” Naimah: Okay, now let's talk a little bit about some of the initiatives at Genomics England. Can we talk about how they've progressed and what they might look like in the future. Rich: Yeah, so we really are on a journey both as an organisation but with all of those partners that we work with across the UK system. And one of the great things I think about genomics and genomics in the UK is that the ecosystem that we're in and the strong partnerships that we can form to ask these really big questions. So, if you like when we formed as an organisation we had the questions that we're asking around diagnostic use of whole genome sequencing in the 100,000 Genomes Project. And if you like in our second chapter as we've moved on to support the NHS in delivery of life clinical care we also have been thinking about the other big questions that we need to address. And those have played out and we've been really fortunate to gain the funding and to work in partnership with the NHS and others on these big questions. So, firstly our newborn genomes programme, secondly our diverse data programme and then our cancer 2.0 initiative. And each of them have big questions behind them so that we're saying, you know, where could genomics better support healthcare and move forward and improve care for everyone. Our vision at Genomics England is a world where everyone can benefit from genomic healthcare and each of them is pushing those boundaries, asking those questions in different ways. For the newborns programme the big question is should every newborn baby be offered whole genome sequencing driven particularly by that potential to identify more treatable severe genetic conditions at birth, and if so how should we do that. Again, developing evidence in and around really broadly across the clinical and scientific aspects, but also engaging and understanding public attitudes how we might do that. And really understanding how that might impact on the healthcare system, how it might be delivered in clinical care. For the diverse data initiative we recognise the challenges historically that there have been because of the inequity in terms of the communities who have been engaged with and included in genomic research. And the diverse data initiative aims to both understand where we are today but also to make sure for example the national genomic research library is at least representative of the UK population so that we can work towards again that word that's in our vision, everyone, a world where everyone can benefit from genomic healthcare. And in the cancer 2.0 initiative we've been exploring two really promising areas in terms of cancer genomics. Firstly, exploring different sequencing technologies and in this case partnering with the NHS to work on the Oxford Nanopore technology which we think is really promising in terms of use in diagnostics to speed up and better diagnose and treat cancers. And also looking in our multimodal element of our cancer 2.0 initiative at bringing in a broader range of data alongside the genomic and clinical data that participants in our programme consent to us holding in our trusted research environments. And bringing in image data, images of their tumours on the histopathology slides that are looked at traditionally down a microscope but scanning those at very high resolution and with uniformity between participants working with NPIC to do that. And also bringing in imaging, so radiology type imaging, of tumours so that that data is there to drive new discovery. And working in partnership with academics and with industry for example insitro to understand how we can both bring that data together usefully, put the right tools next to it and then allow that discovery so that our participants know that we're looking not just on what we know today but to improve things for the future. Naimah: Rich mentioned some of our initiatives here at Genomics England. And now we're going to hear from some G Word guests on how these programmes can make a difference for those with a genetic diagnosis. We spoke to Lizzy Mordey, a clinical trials co-ordinator, whose husband Steve sadly passed away last year after receiving a sarcoma diagnosis. Lizzy commented on the pivotal role whole genome sequencing can play in receiving a quicker diagnosis on the identification of suitable treatments for patients with sarcoma. “Personally, I would hope for quicker diagnosis, and I know that's super hard to do and I think as we've discussed before on this call it's such a rare thing and it, kind of, often doesn't fit the standard clinical pathway and that's one of the reasons why it's so frustrating. So, anything that we can do on that front that I think would be hugely valuable to anyone experiencing a journey like what me and Steve went through, and yes advances like genome sequencing are really amazing in supporting that. Yes, as I mentioned as well any information about types of treatment, you know, the diagnosis is important but then the other aspect of getting a diagnosis and a specific diagnosis is understanding what's most likely to help.” Naimah: Next we're going to hear from David Bick who is a principal clinician for the Newborn Genomes Programme at Genomics England. He spoke about the generation study which is being delivered in partnership with the NHS. “I'm doing this because I imagine a day when all over the world we will find and treat children before they get ill. This is one of the most wonderful programmes to be involved with because I can see that future. I want there to be a healthcare system. I really want to help children stay healthy and really live their best lives, that's what's so exciting for me.” Naimah: Now let's get back to the interview with Rich. You mentioned all of the partnerships there and also one important one is with the NHS. As you know the NHS also celebrated its 75th anniversary year as well as our tenth anniversary. And I wondered if you could tell me a bit more about that relationship with Genomics England and the NHS and how we're working together.  Rich: Our relationship with the NHS is absolutely critical. So, as we're thinking about what we can do to enable better genomic healthcare we're so fortunate in this country to have a national healthcare system. And for us and for our work at Genomics England it's absolutely critical to work hand in hand with NHS England both in supporting their live clinical services so we enable their national whole genome sequencing service through the Genomic Medicine Service and also as we work through all of our patient facing research. So, as we did for the 100,000 Genomes Project, as we are for our Newborn Genomes Programme and so forth co-designing these programmes so that the evidence that we're able to generate is relevant in the UK for our healthcare system but also that national scale is just so extraordinarily powerful. And I think we're really lucky for many reasons, the UK genomics ecosystem, it's richness, the investment that has come from government and from the NHS in genomics and the recognition of its importance and from funders, and then that ability to ask questions at national scale. And when you look internationally I think that's the piece that people are often most jealous of in terms of the power of the questions that we can ask together with the NHS so that we can do exactly what we want to do which is transform care so that it's better in the future. Naimah: Rich highlighted the importance of our relationship with the NHS in transforming patient care. Louise Fish, CEO of Genetic Alliance UK commented on the importance of joined up care following diagnosis to support them throughout their lives. “So, there is a lot more we need to do to work with the NHS to make sure that the care from the health service is joined up and co-ordinated for people. And then beyond that how does the co-ordination reach out to education, to housing, to benefits, to social care. The bit that almost should be simplest is if the NHS has someone who understands your child's condition. But it should be possible for their school to be in touch and to find out how that condition is going to affect them and what support the school might need to put in place through an education health and care plan, but those links out to the other services aren't there either. So, for us there is a lot of work to do that's not just around the diagnosis but it's about ensuring that lifelong care and support is delivered in a co-ordinated way. And as more people are getting genetic diagnosis through this amazing, kind of, clinical advances how do we make sure there is also investment into the clinical services that are going to support people throughout their lives.” Naimah: One of the key factors in supporting Genomics England to deliver this important work and all of our initiatives is the participants and the trust that they have in us. I wondered if you could share a bit more on this, so how Genomics England works with their participant panel. Rich: Yes, so I think one of the things I'm proudest about at Genomics England and it was established about the time I was arriving at the organisation is the participant panel who are a group of our participants who represent a broader participant across the national genomic research library. And they're a part of our governance, which governance sounds like a boring word, our relationship with the participant panel and their role in our governance is absolutely critical. They are the people whose data we are the custodians of, and we have a responsibility to them to live up to their expectations and also to make sure that they're driving the decisions that we're making. An example is how we setup the access to data for researchers. So, I mentioned that the way the national genomic research library works and a model that we developed through engagement with the public and with the input of our participants is that people can visit the de-identified data in our trusted research environment, but they can't take it away. They come and look at the data, they carry out their research which is on approved projects that is exploring healthcare questions. Those researchers have to go through an access process overseen by an independent access review committee that has our participants on it. So, they are making the decisions about the sort of research that they are comfortable with and that they want to be done on their data, and I think that's really critical. It has also been a real pleasure to work with our participants as we design future programmes either on for example finding further answers or looking for better treatments for people who are already in the national genomic research library, already a part of our participants or to help us design future programmes, for example our Newborn Genomes Programme. Our participants as well as engagement with potential future participants and the public more broadly has been absolutely critical in guiding us on how we do that. It's a team sport what we're doing in many different ways. That's with our broader ecosystem, it's with our participants, and that means this isn't about some people going away and sort of thinking up what sounds like the right programme and using all of their knowledge and expertise and producing something which is set in stone. This is about dialogue and engagement and using that to understand the right way of us approaching the questions we are and responding to what we hear. And our participant panel are absolutely critical in that. Naimah: And maybe it would be good now to discuss a bit about the new challenges that we're currently facing such as AI and issues with data sharing and data protection. Can you comment a bit on that. Rich: Yeah, so genomics is a fast moving area. We're really proud of the impact that we've had already, but we also recognise that at the moment we can only use genomics in a particular number of clinical situations. And even within those we can only help a certain proportion of patients. And what our participants say to us is that we need to be restless if you like and not accept where we are today. I think it's quite easy to merely celebrate progress but it's really important to also then ask where we need to be going next. I'm always guided by our participants thinking about what the new technologies are and what the different ways of approaching these scientific questions is critical. We're in an extraordinary time, genomic technology has changed enormously. The power to analyse genomic data has changed enormously. These are big changes in terms of the sorts of analytics that AI could bring and the potential to work not just within the UK but with other countries and other big initiatives to make sure that we're answering the questions as best we can. That brings with it as with all of these areas questions about how you best do things and how you balance the importance of privacy, data privacy, with the benefits of being able to look across larger number of research participants to find answers that you just wouldn't otherwise. Likewise with AI there is the potential for us to both speed up current processes but also ask broader questions that we can't yet using some of these technologies. Doing that in conversation with our participants and the public to understand how to best balance the different benefits and also clarify where there are, sort of, very clear expectations that we shouldn't exceed is really important. And I think that's one of the things that puts us in such a strong position is that confidence that our participants are guiding us and often, and speaking as a doctor myself, it's interesting the medical community is often quite paternalistic, quite cautious and quite narrow in what they might think their participants would want. What we like to do is be driven by what our participants want and expect, and I think that has been really important for us in our history up to now as an organisation and increasingly in the future. Naimah: Yeah, and I think you've really highlighted how Genomics England were trying to keep the participants at the heart of everything that we do. Dr Nicola Byrne, the National Data Guardian for health and adult social care in England spoke about challenges with sharing health data and the importance of transparency and accountability in how data is used to support better outcomes from health and care services. “So, it's absolutely important that people feel that they can share that information and then feel confident that any information they do share is going to be used in ways that are safe, appropriate and ethical. Whether that's for their own care or thinking about the benefit of other people in future through research, innovation and planning.” Naimah: Well, let's get back to the interview for some final reflections with Rich. So, we've been looking back at our achievements over the last ten years, and I'll be keen for us to look at what's next. So, we've touched on it, but let's take some time to reflect on the research that has taken place across the global genomic landscape for example and, you know, what we've done here at Genomics England. Rich: The world has changed a lot in ten years. We've learnt a lot ourselves as an organisation and the researchers that work with our participants data and the national genomic research library have done extraordinary work. So, to give you a flavour of the sorts of things that I guess have changed in terms of what we can enable them doing in terms of research and research work. When participants data enters the research library they're consenting to their genomic data sitting there alongside deidentified clinical data from their longitudinal health records. As I said through our multimodal cancer initiative we're also now able to bring in image data for our cancer participants. And increasingly, and this is something that Matt Brown, our chief scientist, was talking a lot about at our research summit in September, was bringing in additional modalities of data alongside that. So, for example, in our rare disease participants bringing in proteomic, transcriptomic and long read data alongside the current sets of data. It means that that resource becomes even more powerful and able to answer a broader set of questions and able to ask questions across a broader set of data in terms of what might be useful for improving the understanding of medical conditions and improving clinical care. So, for example, there has been amazing work over the last few years on cancer and the mutational signatures that are there in tumours. For example, Serena Nik-Zainal's group understanding the patterns of mutation that are there in tumours driven by the underlying biology, not just because it helps us understand how things have happened, but also because it helps us understand about prognosis and how to treat conditions. We've got really exciting early insights from the work on the image data, that multimodal data, working as I said with academia and also looking at the work that insitro are doing. Recognising patterns between you can see down the microscope of a tumour and the genomics. To understand some of those processes that we've just not been in a position to explore before. And I think one of the really powerful pieces of work that is ongoing and will continue to is the ability for researchers and teams within Genomics England to continue to look for answers as our knowledge improves. So, some of the research work that we're doing is discovering some new fields if you like of understanding. We also know that each year literally hundreds of new genes linked to rare conditions are identified. So, enabling research that allows us to go back and look in our existing participants data to see if that new knowledge, that new knowledge about gene to condition links or better understanding of genomic variation means that we can keep looking for and finding things relevant to people who at the moment are research studies, 100,000 Genomes Project, or the Genomic Medicine Service initial testing with today's knowledge or the knowledge of today or whenever their test was couldn't identify because of the limitations of knowledge. Now we can go back and identify through by sharing likely insights of clinical importance with NHS laboratories. We can then pass those findings back to participants and that has been the case in more than 2,000 of our 100,000 Genomes participants already and it's enormously powerful. I think as we think about the direction of travel in the future, I think thinking about how we make sure that the breadth of questions that can be addressed for our participants in the national genomic research library is even broader, is really important. And that's, as I say, something that's particularly bringing in other types of data alongside has been a really important part of. We're also looking to the future where as I say we're proud of the impact that there already has been, and the NHS Genomic Medicine Service is the first national healthcare system to offer whole genome sequencing and that is extraordinary. Thinking about how we can broaden our impact is a really important part of that, and that's thinking about how we can be supportive of genomic technologies broader than just whole genome. So, for example,  panel and exome data and thinking about some of those other modalities of data like transcriptomes is really important as well for us. And that's something that we're exploring at the moment how we best do that, how we might do that. Also thinking about the range of settings that genomics is currently playing a role and we can see a future in five to ten years' time where rather than genomics being something where it plays a role in a small proportion of healthcare encounters where it could be impactful, over a much larger proportion, perhaps even up to a half of all healthcare encounters through, for example, pharmacogenomics potentially. And our Newborn Genome Programme is developing evidence that will help us understand whether that whole genome sequencing should be offered to all newborns. Potentially in research studies like Our Future Health are asking questions around the value of integrated or polygenic risk scores. Through those sorts of elements we can see genomics playing a role much more broadly both in terms of the number, proportion of clinical settings where it's relevant, much more towards it being a routine part of healthcare, but also across the lifetime at different stages and thinking about the value of genomic data if you like through the life course as something that can be looked at repeatedly increasingly without requiring specialist knowledge from the clinical teams so that it can have the impact it can. And thinking about how we might play a role in developing that evidence but also supporting the infrastructure through our expert knowledge in the management of coherent national genomic data sets. And also having that dialogue in public about how genomic data might be used and working out how we generate evidence that can drive policy change. I think there is enormous potential in the future and we in the UK I think remain uniquely placed to explore those sorts of questions. Naimah: So, we'll wrap up there and that brings us to the end of our podcast for 2023. Thanks to Rich Scott for sharing his reflections on the last ten years of Genomics England and his aspirations for the future. Moving into the new year we'll leave you with a powerful quote from our podcast with Dr Francis Collins who is renowned for his landmark discoveries and leadership in the Human Genome Project.  “My dream Chris is that we come up with in the next decade a scalable approach to every genetic disease where you know the mutation.” You can find all of the podcast episodes mentioned in this podcast plus many more on our website www.genomicsengland.co.uk or on your favourite podcast app. We look forward to bringing you some new episodes with more exciting guests in the New Year but do get in touch if you have any topics you would like us to cover. I've been your host Naimah Callachand, and this episode was edited by Mark Kendrick at Ventoux Digital. Thank you for listening.  

Profesor Jan Marek patří k mezinárodně uznávaným odborníkům v dětské kardiologii a diagnostice vrozených vad srdce. Je nositelem stříbrné medaile Jana Masaryka. Od ministra zahraničních věcí dostal cenu Gratias agit za šíření dobrého jména České republiky v zahraničí. Pár let před padesátkou vyměnil kariéru úspěšného lékaře v dětském kardiocentru v Motole za post v jedné z nejlepších dětských nemocnic na světě – Great Ormond Street Hospital v Londýně. V čem je tak výjimečná?Všechny díly podcastu Host Lucie Výborné můžete pohodlně poslouchat v mobilní aplikaci mujRozhlas pro Android a iOS nebo na webu mujRozhlas.cz.

Rob from Gold Mountain Games (who have been going from strength to strength) returned to discuss what they've been up to in the six months since the whole OGL debacle. We discuss Balder's Gate 3, Resident Evil, Bards (horny and non-horny), and Squidge's ideas for Apple stores.Remember that you can always get in touch with us on our Facebook page, on Twitter, or with our Contact page.Content WarningUsually, we'll add warnings here about swears and such, but with this episode, there was some background noise on Rob's audio. Squidge (our hard-working editor, and audio engineering expert) did everything he could to isolate and remove it, but there's one part where it's a little rough: 23:16 when Rob is describing the game SCUM.We hope the background noise doesn't take you out of the episode too much.Show NotesFrom active timer battling to zombie slaying, Waffling Taylors covers video games beyond.In part one of this episode, we are joined by Rob from Gold Mountain Games. We reminisce about gaming as we grew up, as well as covering everything from ram-raiding shop windows as pirates-for-dummies to the dangers of horny warlocks. Yeah, you'll have to wait for that one.So, without further ado, sit back, grab some snacks, and get ready for this episode entitled "A Catch-up with Rob, No Bards Allowed - Part One"Enjoy.— SquidgeFor this episode, Rob from Gold Mountain Games made his second-ever appearance on the show and wanted to talk about all things video games. You might remember him from his previous appearance where both he and his business partner Tim discussed the (then) impending changes to the Dungeons & Dragons license agreement (the Open Game License of OGL) - here's a link to that episode.But before any of that, it was important to have Rob talk about Gold Mountain Games in his own words:So, Gold Mountain Games: we are a small tabletop RPG production studio. And one of the things that's changed since last time we spoke is that we are now a tabletop production company rather than a [D&D] fifth edition production company, which is quite... I think that lots of people have done that because of what happened.But yeah, so we have our own setting, as you've mentioned, the Salt Reach Isles. We've had a successful Kickstarter for a Zine... And that focuses on one of the cities that we've written. It's got some species in it, it's got some monsters, some spells, and we are currently editing the second magazine for that. So that's going to be coming to Kickstarter in a couple of months.We've got some streams being recorded, so we've got one in our setting. We're about to start Baldur's Gate: Descent into Avernus, partly because Baldur's Gate 3 is coming out, which is very exciting. I'm desperately stopping myself starting another playthrough before they release it fully. And that's also interesting because we've got two complete noobs playing it. So they know nothing about D&D at all....And then the other thing we've got going on at the moment, which I'm really excited about, is Dark Legacies is an amazing franchise written by Chris McCauley and Claudia Christian from Babylon 5 fame. And they've got two comics out of four out so far. There's going to be a miniatures game, there's going to be, apparently an animated TV series. There's a card game.And we've just signed a contract with them to publish their RPG, which is like Dark Legacy's Corporation Wars, it's called. I actually got some of the content yesterday and had a read through it and it's really good. It's a mixture of that kind of the Cyberpunk that you know and love with a bit of that really Dark Judge Dredd style in it. It's got bits of the Expanse in there as well. It's really interesting and I'm really excited that we're going to be publishing that... We'll be publishing the main book and then we'll also be creating more content for it. We're going to have a live stream of it as well. There's a lot of exciting stuff coming out of it.— RobSo if you're interested in tabletop gaming, Babylon 5, Cyberpunk (the tabletop RPG game, that is) and/or the futurism and grim dark of Judge Dredd, then you should be checking out Gold Mountain Games.Dungeons & Dragons, Tabletops, and NovelsAnd speaking of D&D, at the time of recording Jay was reading through Aaron A Reed's 50 Years of Text Games: From Oregon Trail to AI Dungeon - which he was a Kickstarter backer for - and talked about how interesting it is that a lot of the earliest PC games where based on either D&D or the tabletop war games that inspired Gary Gygax to come up with D&D. Which reminded Rob of his first video game memory:I was in Great Ormond Street Hospital when I was six or seven. And in there they had, like, a play area on the children's ward, and they had a computer in there and they had this text based game where you were walking through the woods and you had to find the witch's hut and avoid getting killed by the witch. And that was all.I'd completely forgotten it until you started talking about that. But yet that's probably my earliest memory of a computer game is exactly that. It's sitting there in a hospital of all places going, "oh, choose your Own adventure."I wonder how much fighting fantasy had to do with it as well.— RobAnd Squidge summed up video game history and D&D's involvement quite succinctly:It's like: early D&D is sort of like [the Rosetta Stone](https://en.wikipedia.org/wiki/Rosetta_Stone) to everything that came afterwards— SquidgeWhat's interesting about Rob's earliest video game memory is that it reminded Jay of the opening scene of Tomorrow, and Tomorrow, and Tomorrow by Gabrielle Zevin - which is an amazing book and filled with references to video games.Full Show NotesCheck out the full show notes for the full list of Squidge's questions, some extra stuff, and some links to related things.Reach out to us on Discord, Twitter, Facebook, or try our brand-new contact page.Links of Interest Join our Discord server and be part of future episodes Our Facebook page Us on Twitter Support us on Ko-Fi Gold Mountain Games On Facebook On Twitter On Instagram On Tik-Tok On Twitch On YouTube Gold Mountain Games on Patreon The Open Game License of OGL Climbing the Gold Mountain with Rob and Tim The Saltreach Isles Zine 1: Zilaram 50 Years of Text Games: From Oregon Trail to AI Dungeon the Rosetta Stone Tomorrow, and Tomorrow, and Tomorrow by Gabrielle Zevin SCUM Larian Studios Signing Off... For NowAnd have you left us a rating or review? We really like to hear back from listeners about our show, so check out https://wafflingtaylors.rocks/our-podcast/ for links to services where you can leave us some wonderful feedback.The Waffling Taylors is a proud member of Jay and Jay Media. If you like this episode, please consider supporting our Podcasting Network. One $3 donation provides a week of hosting for all of our shows. You can support this show, and the others like it, at https://ko-fi.com/jayandjaymedia ★ Support this podcast ★

Martha Mills died after failures in her treatment at King's College Hospital. Martha's mother, Merope, is calling for hospitals around the country to bring in "Martha's rule", which would give parents, carers and patients the right to call for an urgent second clinical opinion from other experts at the same hospital if they have concerns about their current care. The government has said it will explore the introduction of Martha's rule in UK hospitals. Today's Nick Robinson spoke to Dr Sanjiv Sharma, Medical Director at Great Ormond Street Hospital and Matthew Taylor, Chief executive of the NHS Confederation. Nick Robinson also spoke to Sir Robert Francis, chair of the Francis Report and chair of the Freedom to Speak Up Review, published in 2015. (Image, Merope and Martha Mills, Credit Merope Mills)

How can listening help organizations have impact on critical global issues, while understanding and acting upon local needs? This tension is the space our next guest leans into in order to understand the real needs and potential. Jeff Hoffman is a Proven Public Affairs executive for The Walt Disney Company, the world's most storied and admired media and entertainment enterprise. He currently leads The Conference Board's Institute on Corporate Citizenship & Philanthropy, part of the ESG Center. He manages his own firm specializing in global corporate citizenship, ESG (environmental, social and governance), sustainability, philanthropy, and cause marketing.  In this episode Jeff discusses the transformative power of offering a listening ear, which brings about magical experiences that enriches individuals' lives and has positive effects on their company and the community they're a part of. He also shares how he has navigated failures, challenges and successes, where listening or not listening well has played a role. Understand better how to have a bigger impact on global issues, yet adjust to the nuances of local needs. "The important thing about listening is also to understand what you're hearing… really try to pull the facts out of what you're listening to." - Jeff Hoffman Listening SUPERPOWER Notes: 00:33 - That time he experienced the power of listening by giving the people he talked to a magical listening experience 03:36 - What he realizes about the power of listening. 06:00 - Describing the corporate culture at Disney: You want your cast member to be the best and to bring out the richness of their own experiences into their role within the company. 12:13 - Understanding and recognizing everyone's differences: You have to understand where you are and what the needs are, and the differences. 20:35 - How he engages with the communities he serves in a manner that creates a powerful impact on them. 26:20 - Serving together to be effective: Habitat for Humanity International has done an amazing program where you can have volunteers volunteering with the people who are going to live in that home. 29:07 - Neighboring over volunteering 30:24 - Achieving the United Nations Sustainability Goals: It's all about coming together in community and collaboration and service. 35:32 - One important insight to understand about listening Key Takeaways: "... to understand differences, you need to talk to people, but you really need to listen and understand what they're saying."  - Jeff Hoffman "We don't do a lot of telling now. We ask a lot of questions because we want you to tell us. We know (listening) is going to be more effective. And we're seeing that effectiveness where programs today are based on a lot of input from the people who are being served." - Jeff Hoffman Notes/Mentions: Episode 66 with Mary Alice Arthur: https://listeningalchemy.com/allgemein/a-journey-into-the-power-of-storytelling-with-mary-alice-arthur/https://listeningalchemy.com/allgemein/a-journey-into-the-power-of-storytelling-with-mary-alice-arthur/ Great Ormond Street Hospital for Children: https://www.gosh.nhs.uk/https://www.gosh.nhs.uk/ Connect with Jeff Hoffman:    LinkedIn: https://www.linkedin.com/in/hoffmanjeffrey/   Connect with Raquel Ark:   www.listeningalchemy.com Mobile: + 491732340722 contact@listeningalchemy.com  LinkedIn Podcast email: listeningsuperpower@gmail.com

Great Ormond Street Hospital is undertaking the biggest fundraising challenge of a generation – a capital appeal to raise £300 million to build a world-class new Children's Cancer Centre. In this episode of the Fundraising Everywhere podcast we welcome Amy Hutchings, Creative Strategy Director at Open and Jennie Sullivan, Head of Legacy and Donor Development from GOSH who worked on the campaign, called Build it, Beat it. They share the thinking that went into this amazing work to inspire the public to donate on this epic scale. Speakers: Amy Hutchings, Creative Strategy Director at Open & Jennie Sullivan, Head of Legacy and Donor Development at GOSH Want to stay on top of everything that's happening? Sign up to get emails from the humans at Fundraising Everywhere & Everywhere+ with cracking fundraising tips, news, promos & updates on upcoming events. And thank you to our friends at JustGiving who make the Fundraising Everywhere podcast possible.

Today I talk about my feel good formula and how you can use this in your life. I am running a 10k for charity on Sunday 14th May for a charity close to my heart helping ill and vulnerable children, Great Ormond Street Hospital. If my story or this resonates with you any donation would be hugely appreciated: ⁠greatbristolrun2023.enthuse.com/pf/jonny-pardoe⁠ Thank you. Disclaimer: these podcast episodes are sharing my personal experiences, stories from mentors and guests around self esteem, confidence, personal growth and mental health. For any serious mental health concerns and advice please consult with a professional such as a doctor, therapist or what seems appropriate.

Today I talk about self confidence and responsibility. I am running a 10k for charity on Sunday 14th May for a charity close to my heart helping ill and vulnerable children, Great Ormond Street Hospital. If my story or this resonates with you any donation would be hugely appreciated: greatbristolrun2023.enthuse.com/pf/jonny-pardoe Thank you. Disclaimer: these podcast episodes are sharing my personal experiences, stories from mentors and guests around self esteem, confidence, personal growth and mental health. For any serious mental health concerns and advice please consult with a professional such as a doctor, therapist or what seems appropriate.

For Episode 137 of the Wealth On Any Income Podcast, Rennie is joined by Jonathan Jay. Jonathan has been an entrepreneur successfully buying and selling businesses for over 30 years. He has built businesses in publishing, digital marketing, adult education and coaching, and preschool education - and sold each of them. Jonathan is now passionate about sharing his life experience to help others successfully buy businesses through his consultancy company, Dealmakers.Jonathon is an advocate of a healthy work-life balance, after suffering mental and physical burnout himself, he now believes you can achieve success without business taking over your life.He helps other people buy businesses and helps them avoid the expensive mistakes - as he says he has made them all!Are you ready to learn how to create wealth buying and selling businesses?In this episode, Rennie and Jonathan cover:01:52 How Jonathan realized a different way of being in business - buying and selling businesses.04:44 Jonathan's two favorite charities The Great Ormond Street Hospital for Children (https://www.gosh.nhs.uk/) and his seven-year-old daughter's all-girls school in London.05:45 Who Jonathan's clients are - the people who he helps to buy & sell businesses.07:22 A recent challenge that Jonathan faced and what he learned from it about himself.12:59 To get hundreds of videos all about buying and selling businesses visit Jonathan's YouTube channel at https://www.youtube.com/@thedealmakers.14:16 Jonathan shares who he feels can buy a business successfully and the person you become in the process of buying and selling businesses.“Many years ago in the 1990s, I had a publishing business. On one particular day, I will never forget it, someone approached me and said that they wanted to buy the business. I never thought that was ever going to be possible that I would sell this company - and I did the deal. I sold the business and I made more money the day I sold that business than I had in the previous two and a half years of owning and running the business. So, to put that another way, I'd worked very, very hard seven days a week for two and a half years and then I sold it and I made more money than all that effort combined. That opened my eyes to a different way of being in business.” – Jonathan JayTo get hundreds of videos all about buying a business visit Jonathan's YouTube channel at https://www.youtube.com/@thedealmakersTo learn more about Jonathan and Dealmakers visit https://www.thedealmakersacademy.com/about-us/If you'd like to know how books, movies, and society programs you to be poor, and what the cure is visit wealthonanyincome.com/tedx. You'll hear Rennie's TEDx talk and can request a free 27-page Roadmap to Complete Financial Choice® and receive a weekly email with tips, techniques, or inspiration around your business or money. AND if you'd like to see how you can increase your wealth and donate to the causes that touch your heart. Please check out our affordable program ‘Wealth with Purpose'.Rennie's Books and Programshttps://wealthonanyincome.com/books/Wealth with Purpose:https://wealthonanyincome.com/wealthwithpurposeRennie's 9 Days to Financial Freedom program:https://wealthonanyincome.com/programsConnect with Rennie Websites:WealthOnAnyIncome.comRennieGabriel.comEmail: Rennie@WealthOnAnyIncome.comLinkedIn: https://www.linkedin.com/in/renniegabriel/Facebook: https://www.facebook.com/WealthOnAnyIncome/Twitter: https://twitter.com/RennieGabrielYouTube: https://www.youtube.com/channel/UCdIkYMOuvzHQqVXe4e_L8PgInstagram: https://www.instagram.com/wealthonanyincome/

The Third International Summit on Human Genome Editing was held this week in London. It was the first such meeting since 2018, when a Chinese researcher announced that he had created the world's first genetically edited babies—a move that was roundly condemned at the time. Host Alok Jha and Natasha Loder, The Economist's health editor, report from the conference to explore the exciting future—and knotty challenges—of the world that gene-editing therapies could create.Robin Lovell-Badge, a leading scientist at the Francis Crick Institute in London and the organiser of the summit, explains how genome-editing technology has rapidly advanced in recent years. Claire Booth, a professor of gene therapy and paediatric immunology at Great Ormond Street Hospital and University College London discusses the hopes of gene-editing treatments. Plus, Kelly Ormond, a bioethicist from ETH-Zurich, explores the ethical dilemmas that are raised by the technology, and Filippa Lentzos of King's College London, explains why human genome editing presents potential biosecurity risks.Listen to previous episodes of “Babbage” on the topic: the gene therapy revolution and an interview with Jennifer Doudna, the pioneer of CRISPR-Cas9 technology. For full access to The Economist's print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience. Hosted on Acast. See acast.com/privacy for more information.

The Third International Summit on Human Genome Editing was held this week in London. It was the first such meeting since 2018, when a Chinese researcher announced that he had created the world's first genetically edited babies—a move that was roundly condemned at the time. Host Alok Jha and Natasha Loder, The Economist's health editor, report from the conference to explore the exciting future—and knotty challenges—of the world that gene-editing therapies could create.Robin Lovell-Badge, a leading scientist at the Francis Crick Institute in London and the organiser of the summit, explains how genome-editing technology has rapidly advanced in recent years. Claire Booth, a professor of gene therapy and paediatric immunology at Great Ormond Street Hospital and University College London discusses the hopes of gene-editing treatments. Plus, Kelly Ormond, a bioethicist from ETH-Zurich, explores the ethical dilemmas that are raised by the technology, and Filippa Lentzos of King's College London, explains why human genome editing presents potential biosecurity risks.Listen to previous episodes of “Babbage” on the topic: the gene therapy revolution and an interview with Jennifer Doudna, the pioneer of CRISPR-Cas9 technology. For full access to The Economist's print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience. Hosted on Acast. See acast.com/privacy for more information.

This week Cariad talks to Paines Plough artistic director Charlotte Bennett and her seven-year-old niece, Illy joins aswell. They talk about Margot, Charlotte's baby daughter who died just 24 hours after she was born and her mum, who died not long after from pancreatic cancer

In Rio de Janeiro, surgeons separated 3-year-old conjoined twins Arthur and Bernardo Lima in June. When the twins were born, they were attached at the head, their brains intertwined. Separating them would require dozens of complicated surgeries. To prepare, the twins’ doctors in Rio used 3D printed models of the kids’ brains and they practiced the surgeries in virtual reality, using goggles and controllers while connected to another medical team in London that had done this before. Marketplace’s Marielle Segarra speaks with Noor ul Owase Jeelani, a pediatric neurosurgeon at London's Great Ormond Street Hospital. His team led the VR training, and then he flew to Brazil to be one of the lead surgeons on the case.

In Rio de Janeiro, surgeons separated 3-year-old conjoined twins Arthur and Bernardo Lima in June. When the twins were born, they were attached at the head, their brains intertwined. Separating them would require dozens of complicated surgeries. To prepare, the twins’ doctors in Rio used 3D printed models of the kids’ brains and they practiced the surgeries in virtual reality, using goggles and controllers while connected to another medical team in London that had done this before. Marketplace’s Marielle Segarra speaks with Noor ul Owase Jeelani, a pediatric neurosurgeon at London's Great Ormond Street Hospital. His team led the VR training, and then he flew to Brazil to be one of the lead surgeons on the case.