Podcasts about MSI

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Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Het weekend komt eraan. Morgen is het zover. En dat kan vandaag maar één ding betekenen. Inderdaad, we gaan dat weekeinde feestelijk inluiden met een nieuwe editie van Einde van de Week Live. De talkshow waarin we elke week het belangrijkste game gerelateerde nieuws met jullie, de kijkers doornemen. Deze aflevering wordt een speciale, want hij staat geheel in het teken van Tokyo en de Tokyo Game Show. Vol warme en nostalgische gevoelens kijken we naar al het nieuws wat de afgelopen dagen op ons af is gekomen. Met aan tafel Koos en Jelle. Twee hosts die beide vorig jaar zelf in de Makuhara Messe aanwezig waren. Hoe kijken ze terug op vorig jaar en wat vinden ze van het nieuws dat nu uit Tokyo komt. De PlayStation State of Play, de trailer van Kojima's OD, de aankondigingen van Capcom en ga zo maar door. Dit alles en meer ga je zien en horen in de Einde van de Week Live van vrijdag 26 september 2025. Inclusief een dot Wasabi.Hoe goed was de PlayStation State of Play?Einde van de Week draait niet alleen om het bespreken van al het nieuws. Lol maken is ook een belangrijk onderdeel. En die lol ga je volop voorbij zien en horen komen in deze uitzending. Bijvoorbeeld in een Japans getinte editie van Cool & Serious Uncool. Schenk dus maar snel een glaasje sake in.Krijg 250 euro korting op de Katana 15 HX gaming laptopDeze week zet MSI opnieuw de Katana 15 HX in de spotlights. Een krachtige gaming laptop met aan boord een 14e generatie Intel Core i7 HX processor, een RTX 5060 videokaart, een 15.6” 144Hz display, een 512GB SSD en een 4-zone RGB toetsenbord. De Katana 15 HX is momenteel hier bij BOL verkrijgbaar met een lekkere 250 euro korting.Timestamps:00:00:00 Einde van de Week Live van 26 september!00:01:14 Huishoudelijke mededeling: MSI00:05:04 Tokyo Game Show00:15:26 Kojima, en de trailer van OD, op de Tokyo Game Show.00:24:35 De hoogtepunten van de PlayStation State of Play.00:34:54 Nieuwe trailer van Pragmata getoond tijdens TGS 00:37:38 Xbox kondigt aan dat Forza Horizon 6 zich in Japan zal afspelen.00:41:18 Tweede grote aankondiging van Xbox was Gungrave GORE Blood Heat. 00:43:47 Tokyo Game Show voedselcollaborations. 00:49:10 Metal Gear Solid Delta: Snake Eater Fox Hunt mode komt eind oktober.00:55:36 ROG Ally X prijs en releasedatum bekendgemaakt.00:58:50 Voorjaar 2026 worden dure maanden dankzij GTA 6.01:00:56 Er komt een Nintendo pop-up store in Lond

The Trump administration is cutting off or moving funding for TRIO, GEAR UP, and MSI programs—even though Congress approved the money. Hosts Mushtaq Gunja, Jon Fansmith, and Sarah Spreitzer explain what's happening, why it matters, and what colleges should do next. ACE President Ted Mitchell also joins to discuss the need to protect free expression and civil dialogue on campus following the murder of Charlie Kirk. Here are some of the links and references from this week's show:  U.S. Department of Education Ends Funding to Racially Discriminatory Discretionary Grant Programs at Minority-Serving Institutions  Department of Education | September 10, 2025  Trump Administration Delays $660M for College Access Programs  Inside Higher Ed | September 12, 2025  Trump Redirects Millions to Historically Black Colleges, Charter Schools  The New York Times (sub. req.) | September 15, 2025  RESTRICTION ON ENTRY OF CERTAIN NONIMMIGRANT WORKERS   White House | September 19, 2025  Trump to Impose $100,000 Fee Per Year for H-1B Visas, in Blow to Tech  Reuters | September 20, 2025  White House Tries to Tamp Down Corporate Panic for High-skill Visa Holders after Last-minute Overhaul  Politico | September 20, 2025 

Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Drie heren zitten klaar achter de desk, te weten Huey, Jasper en Koos. Zij gaan jullie een nieuwe episode van Einde van de Week Live voorschotelen. De talkshow waarin we wekelijks het belangrijkste game gerelateerde nieuws met jullie doornemen. Met dit keer onder andere de speelsessie van Jasper met de grootste map van Battlefield 6. Is de game klaar voor launch? Verder praten de drie over de nieuwe details over Assassin's Creed: Black Flag Remake, de komst van de beta van Call of Duty Black Ops 7 en de 'controverse' over de hoge moeilijkheidsgraad van Hollow Knight: Silksong. Dit en veel andere gespreksonderwerpen zie en hoor je voorbij komen in de Einde van de Week Live van vrijdag 19 september 2025.De releasedatum van Battlefield 6 nadert snelAndete onderwerpen in EvdWL zijn onder meer een mogelijke nieuwe Like a Dragon-game, de verrassende nieuwe game van Bohemia Interactive en de casting van de belangrijkste karakters in de Mass Effect tv-serie.Krijg 250 euro korting op de Katana 15 HX gaming laptopDeze week zet MSI opnieuw de Katana 15 HX in de spotlights. En met een goede reden. De Katana 15 HX is een krachtige gaming laptop die namelijk gebruik maakt van de nieuwste 14e generatie Intel Core i7 HX processor. Dit terwijl de vergelijkbare laptops van de concurrentie vaak een 13e generatie i7 processor of een AMD Ryzen 7 bevatten. Je krijgt dus de beste performance. Ter ondersteuning van dit statement van MSI hebben we de benchmarks voor je klaarstaan. Verder bevat de laptop een RTX 5060 videokaart, een 15.6” 144Hz display, een 512GB SSD en een 4-zone RGB toetsenbord. De Katana 15 HX is momenteel hier bij BOL verkrijgbaar met 250 fijne euro's korting: https://msi.gm/S36E5F1C .Zet je eigen PC in elkaar tijdens de EZ DIY Workshop van MSIOp 4 oktober organiseert MSI in samenwerking met Paradigit in Eindhoven een zogenaamde EZ DIY (Easy, Do It Yourself) Workshop. Mocht je van plan zijn een nieuwe desktop te willen kopen, dan kan kun je die nu in de webshop van Paradigit samenstellen, waarna hij die dag voor je klaarligt. De PC wordt vervolgens met de hulp van PC-experts stap voor stap in elkaar gezet. Na afloop heb je dus een dikke PC die werkt én je weet voor de volgende keer hoe je het zelf kan doen. Interesse? Meld je hier aan: https://www.paradigit.nl/powered-by-msi/diy-workshop/ .Timestamps:00:00:00 Einde van de Week Live van 19 september00:00:20 Huishoudelijke mededeling: MSI00:03:02 Nog een huishoudelijke mededeling: Playstation Top 10 item.00:05:53 Nieuwe maps en modes in Battlefield 6; een teaser van Jasper.00:11:03 Call of Duty Black Ops 7 closed en open beta komen respectievelijk 2 en 5 oktober.00:13:41 Nieuwe details over de Assassin's Creed: Black Flag Remake. 00:23:32 Ryu Ga Gotoku Studio komt al snel met een nieuwe Like a Dragon game.00:26:51 Developer Hollow Knight: Silksong reageert op hoge moeilijkheidsgraad. 00:30:15 Bohemia Interactive heeft het bij hun nieuwe IP over een andere boeg gegooid.00:32:00 BULLETTÎME: MSI00:35:43 Mass Effect hoofdrolspelers zijn gelekt is.00:38:43 Schietlood voor memes nu Borderlands 4 het moeilijk heeft qua technische prestaties. 00:42:36 Dit bericht van de Arnhemse game-expert...00:45:52 Nieuwe geanimeerde tv-serie gebaseerd op de Splinter Cell franchise00:48:46 Nintendo Direct trok meer kijkers dan het Apple event.01:03:49 Deze man spaart alles van Super Mario en heeft inmiddels meer dan 500 Mario games.01:08:33 Meta komt met de Meta Ray-Ban Display AI bril.01:11:28 Cool of Serious Uncool?

Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Het weekend staat voor de deur. En dat kan maar één ding betekenen. Inderdaad, je krijgt een nieuwe editie  op te van Einde van de Week Live voor de spreekwoordelijke kiezen. De talkshow waarin we elke week het belangrijkste game gerelateerde nieuws met jullie, de kijkers doornemen. Deze aflevering wordt een speciale, want naast een uur gezellig gekwebbel over de laatste nieuwtjes en roddels, kijken we ook mee naar de Nintendo Direct. Plus een korte nazit natuurlijk. Een bomvolle editie dus die ook ingaat op het bizarre patent van Nintendo dat de game-wereld in de greep heeft, de launch van Borderlands en de eerste details van de battle royale mode van Battlefield 6. Dit alles en meer ga je zien en horen in de Einde van de Week Live van vrijdag 12 september 2025.Heeft de Nintendo Direct ons blij gemaakt?In deze uitzending komt Kevin ook even langs. Er staan immers nog een paar losse eindjes open wat Hollow Knight: Silksong open. Is de game beter dan zijn voorganger en vanwaar de hype? Plus wat Kevin dat er straks bij de Nintendo Direct getoond wordt?Krijg 250 euro korting op de Katana 15 HX gaming laptopDeze week zet MSI de Katana 15 HX in de spotlights. Een krachtige gaming laptop met aan boord een 14e generatie Intel Core i7 HX processor, een RTX 5060 videokaart, een 15.6” 144Hz display, een 512GB SSD en een 4-zone RGB toetsenbord. De Katana 15 HX is momenteel hier bij BOL verkrijgbaar met een lekkere 250 euro korting.Pak 600 korting op de 32-inch GS95UV-B monitor van LG UltraGearDe LG UltraGear OLED 32GS95UV-B monitor is de monitor waar Koos thuis zijn games op speelt. Op dit bakbeest speel je games met in een 4K resolutie met een verversingssnelheid van 240 hertz. Deze monitor is hier bij Coolblue tijdelijk met 600 euro korting te krijgen. Een niet misselijke aanbieding die we jullie niet wilden onthouden. Op = wel op.

Immunotherapy is not usually effective against pancreatic cancer (PC), but a new study published in Oncotarget (Volume 16, 2025) highlights rare cases where it did help. These examples, though uncommon, may offer valuable insights for future treatment. Pancreatic Cancer and Immunotherapy Pancreatic cancer is often diagnosed at an advanced stage, which limits treatment options and contributes to its poor prognosis. While chemotherapy remains the standard treatment, it usually offers only modest benefits in terms of survival. Immunotherapy—an approach that activates the immune system to fight cancer—has been effective in other cancers but has shown limited success in PC. This is largely due to the tumor's ability to suppress immune responses and create an environment that protects it from attack. Currently, these drugs are only approved for a small subset of patients whose tumors have a specific genetic feature called high microsatellite instability (MSI-high), found in just 1 to 2 percent of cases. The Study: Pancreatic Cancer Immunotherapy Responders The study, titled “Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence,” was led by first author Kavin Sugumar and corresponding author Jordan M. Winter, from University Hospitals Seidman Cancer Center. The researchers examined medical records from 14 patients with pancreatic ductal adenocarcinoma (PDAC) who had responded unexpectedly well to immune checkpoint inhibitors—drugs that help reactivate immune cells to attack cancer. The drugs included PD-1 inhibitors such as pembrolizumab and nivolumab, CTLA-4 inhibitors like ipilimumab, and agents targeting tumor-associated macrophages. To find these rare cases, the research team contacted 471 oncologists from 91 major U.S. cancer centers between 2020 and 2021. Full blog - https://www.oncotarget.org/2025/09/11/immunotherapy-response-in-pancreatic-cancer-what-a-new-study-reveals/ Paper DOI - https://doi.org/10.18632/oncotarget.28739 Correspondence to - Jordan M. Winter - jordan.winter@UHHospitals.org Abstract video - https://www.youtube.com/watch?v=VeWTcuVmqgM Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28739 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, pancreatic adenocarcinoma, immunotherapy, exceptional responders, microsatellite instability, survival To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

We've got a full house today to talk about the Marvel Tokon Beta, Cronos: The New Dawn, finishing Riven, diving all the way into Sudoku, and how Silksong has done more than live up to the hype.HOLLOW KNIGHT: SILKSONG DISCUSSION FEATURING MINOR SPOILERS runs from roughly 1:24:12 to 1:56:28 (variable depending on how many ads you get beforehand).Today's episode is brought to you by our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

Jeff Grubb and Rachel Kaser start your week with rumors of a new Soul Calibur game, a lot of Silksong frustrations happening post launch, progress being made for Final Fantasy 7 Remake Part 3 and Kingdom Hearts 4, and even more stories to kickstart the week. Today kicks off our month-long partnership with our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

Jeff Grubb is joined by Rhiannon Bevan from TheGamer to chat about Hollow Knight: Silksong and Metal Gear Solid Delta sales, Star Wars Outlaws using a game key card, layoffs at Firaxis, MindsEye traumatizing IOI, and even more stories to end the week! Today kicks off our month-long partnership with our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Drie heren zitten klaar achter de desk. We hebben het over Jelle, JJ en Koos. JJ is terug van vakantie en zit zoals hij al zo vaak heeft gedaan deze nieuwe editie van Einde van de Week Live voor. Dus kun je sowieso een aantal leuke verhaspelingen tegemoet zien. EvdWL is de talkshow waarin we wekelijks het belangrijkste game gerelateerde nieuws met jullie doornemen. Met dit keer onder meer de bizarre ontwikkelingen rond de launch van Hollow Knight: Silksong, de rating van Battlefield 6 en de eerste gameplay beelden van de nieuwe James Bond-game 007 First Light. Dit en veel andere gespreksonderwerpen zie en hoor je voorbij komen in de Einde van de Week Live van vrijdag 5 september.Launch Hollow Knight: Silksong sloopt online storesAndere topics die in deze editie van EvdWL voorbij komen, zijn de prijzen van consoles door de jaren heen, geruchten over nieuwe trailer van Wolverine en Kojima die heeft gemeld hoeveel games hij per jaar speelt.Koop de Vector 16 HX AI gaming laptop van MSI en krijg er Borderlands 4 en Battlefield 6 bijMSI zet in deze editie van EvdWL hun Vector 16 HX AI in de spotlights. Deze krachtige gaming laptop met aan boord een Intel Core Ultra 7 processor, NVIDIA GeForce RTX 5070 Ti videokaart, een 240Hz QHD Scherm, 1TB SSD, Thunderbolt 5 aansluiting en RGB toetsenbord, is nu hier bij MeGekko verkrijgbaar tegen een scherpe prijs: https://msi.gm/SD25C197 . Plus je krijgt er, niet geheel onbelangrijk, Borderlands 4 en Battlefield 6 bij.Krijg 10% korting op alle producten van LG tijdens de Member DaysDat LG mooie producten maakt, hoeven we je niet uit te leggen. Dat hebben we al vaak genoeg laten zien. Momenteel lopen de Member Days bij LG. Een mooi moment misschien om 10% te scoren op alle producten van deze hardware producent uit Zuid-Korea. En ja, dus ook op de koelkasten. Hier vind je alle info over de Member Days en hoe je in aanmerking kunt komen voor deze kortingen: https://tinyurl.com/4zvk2zp2 .Timestamps:00:00:00 Einde van de Week Live van 5 september00:07:48 Huishoudelijke mededeling: MSI00:12:07 Hollow Knight: Silksong hype. Shops offline.00:33:05 Battlefield 6 krijgt een mature rating. 00:37:14 Borderlands 4 previews.00:41:33 Eerste indruk van James Bond 007 First Light.00:49:49 De prijzen van consoles. 00:53:11 Apple Event op 9 september.01:01:28 BULLETTÎME: LG01:06:19 Sophie Turner is de nieuwe Lara Croft.01:10:37 Wolverine mogelijk in september bij State of Play.01:13:08 Give-away: Tony Hawk Pro Skater Collection's Edition01:16:35 Xbox en PlayStation X headers. 01:18:10 Delta Force nu ook aan rare skins?01:19:54 Cool of Serious Uncool?

Jeff Grubb and Jan Ochoa are here to start your Thursday with stories about Silksong taking down all of the online stores, Wolverine making a supposed appearance at the next State of Play, 007 impressions, and more! Today kicks off our month-long partnership with our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!Vote on the Bomb 12! https://docs.google.com/forms/d/e/1FAIpQLSfGEh4EWQ0DuPnFyDBaQooUivEvz4jiphqPQijvKSdtjGoH9w/viewform

Jeff Grubb and Jason Fanelli check in on how Cronos, Everybody's Golf Hot Shots, and Daemon X Machina are reviewing. We also check in on news about Take-Two's involvement in th the Perfect Dark Remaster, Resident Evil: Requiem rumors, and more this Wednesday morning.Today kicks off our month-long partnership with our friends at MSI! For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout! Big thanks to MSI for their support!

We're rolling out of a three day weekend and straight to the Bombcast! We chat about the Shinobi game, Gears Reloaded, Magic: the Gathering, Slay the Spire, and more games. We also chat about Nintendo having a direct very soon, Sony's live service Fairgames getting having more issues, Capcom and the Switch 2, a price for Hollow Knight: Silksong, and more!Today's episode is brought to you by our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

Esportmaníacos 2363: En el programa de hoy hemos visto las declaraciones del Commissioner de la LEC sobre el formato y por qué las cosas se han llevado de la manera que se han llevado este año. También hemos visto el T1 vs Gen G en el cuál el campeón del MSI se ha vuelto a imponer y hemos tocado algunos temas de actualidad como el nuevo fichaje de NAVI LEC o la Final Four de Superliga Domino's APÓYANOS AQUÍ https://www.patreon.com/Esportmaniacos https://www.twitch.tv/esportmaniacos 🔁Nuestras redes🔁 https://twitter.com/Esportmaniacos https://www.tiktok.com/@esportmaniacos 💙Referido de AMAZON: https://amzn.to/36cVx3g 00:00:00 - Intro 00:18:20 - Gen G vuelve a ganarle a T1 00:38:15 - Representantes del Game Changers 00:40:45 - Riot responde sobre el futuro de la LEC 01:29:00 - NAVI ficha su head coach para 2026 01:34:30 - Rumores de scrims de LEC 01:44:40 - Repaso de la Final Four de SLD

Jeff Grubb and Lex Luddy round out your week by chatting about a portable PS6 rumor, Final Fantasy XIV cracking down on mods, and the fact that Pragmata is not, in fact, a Mega Man game, MIKE.Today's episode is brought to you by our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Drie heren zitten fris en fruitig klaar achter de desk. We hebben het over Huey, Jelle en Koos. Ze gaanjullie een verse editie van Einde van de Week Live presenteren. De talkshow waarin we wekelijks het belangrijkste game gerelateerde nieuws met jullie doornemen. Met onder andere het gerucht over de nieuwe handheld van PlayStation die sterk op de Switch lijkt, de opvallende switch van Activision als het gaat om de look and feel van de multiplayer van Black Ops 7 en de Hollow Knight: Silksong-hype die GTA 6-achtige proporties aan neemt. Dit en veel andere gespreksonderwerpen zie en hoor je voorbij komen in de Einde van de Week Live van vrijdag 29 augustus.Activision wil geen weirde skins meer in Black Ops 7Andere onderwerpen die aan bod komen zijn onder andere het succes van Helldivers 2 op de Xbox Series X, Ghost of Yotei en MARVEL Tokon: Fighting Souls op de Tokyo Game Show en de verrassende terugkeer van Acclaim als publisher.Scoor 200 euro korting op de pittige Pulse A16 AI+ gaming laptop van MSIMSI zet in deze episode van EvdWL hun Pulse A16 AI+ gaming laptop in de spotlights. Met aan boord een AMD Ryzen AI 9 processor, een RTX 5070 GPU, een 16” 240Hz QHD display, 32GB RAM intern geheugen, een 1TB SSD, en een 24-zone RGB toetsenbord. Deze knaap kun je hier met 200 euro korting bestellen.Scoor kaarten voor het concert van Post Malone in het GelredomeWe hebben een nieuw concert die we onder de aandacht willen brengen. Van een artiest waar een aantal van ons graag naar luisteren. Post Malone. Hij treedt op 9 september op in de Gelredome in Arnhem in het kader van zijn The Big Ass tour. Als je houdt van een mix van hiphop, pop, rock en country, dan is de kans groot dat je hier een goede tijd gaat beleven. De kaarten kun je hier kopen.Check de (demo van de) action-adventure Hell is UsHell is Us is een third person action-adventure die draait om de uitdagende battles tegen even brute als bizarre wezens en het exploreren van de omgeving. En dat laatste kun je letterlijk nemen want het spel helpt je niet om de juiste route te vinden. De game komt 4 september aanstaande uit en momenteel kun je de demo op de PC, PS5 en Xbox Series X uitproberen. Hier vind je meer info over deze game.Timestamps:00:00:00 Einde van de Week Live van 29 augustus00:00:29 Huishoudelijke mededeling: MSI00:02:34 Gamescom road trip!00:09:51 PlayStation zou met een Switch-achtige portable komen (inclusief docking station). 00:15:04 Activision erkent dat het is doorgeschoten met de skins en gaat ‘daarnaar kijken' met Black Ops 7. 00:18:18 Ondanks negativiteit denken veel analisten dat Black Ops 7 vanwege ‘autopilot kopers', Battlefield 6 eruit zal verkopen. 00:19:46 Ghost of Yōtei en MARVEL Tokon: Fighting Souls zullen speelbaar zijn op Tokyo Game Show. 00:24:56 Skate. komt in Early Access uit op 16 september.00:33:05 Gezeur over de Unreal Engine 5: De baas van Epic vindt dat de engine zelf niks te verwijten valt en legt schuld bij developers.00:43:25 Augustus tot en met oktober laat een hoop dikke games zien. 00:44:56 BULLETTÎME: Hell is Us (NACON)00:50:27 Goed nieuws voor de ‘oudjes' onder ons? 'Acclaim keert terug' 01:01:01 Dragon's Dogma werd gemengd ontvangen. De ontwikkelaar zegt er geen seconde wakker van de te liggen. 01:07:46 Helldivers 2 gaat (opnieuw) skyhigh, ditmaal dankzij de launch op Xbox. 01:10:44 Al acht indie games uitgesteld vanwege Hollow Knight: Silksong.01:19:12 Sega is flink wat oude games aan het rebooten.01:20:20 Welke van deze zwaarden is het meest iconisch?01:22:22 BULLETTÎME: Concert van Post Malone (MOJO) 01:28:35 Cool of Serious Uncool?

Jeff Grubb and TurboShawn know how to do a podcast with ZERO tech issues, and they're bringing you one today featuring news about Resident Evil Requiem's main character arc, Tim Sweeney blaming devs for Unreal Engine issues, and a Dino Crisis remake happening... And then *not* happening.Today's episode is brought to you by our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

If it feels like med spas are turning into wellness clinics, that's because they kind of are. It's not just about Botox and laser anymore; it's peptides, metabolic health, hormone balancing, and even the little pink pill. In this episode of ASCP Esty Talk, Maggie and Ella discuss how med spas are shifting away from traditional esthetics services and expanding into whole-body health. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE   TiZO Mineral Sunscreens set the standard for aesthetic elegance with tinted and non-tinted formulas for use on virtually all skin types and tones. Our name reflects our commitment: TIZO = Titanium dioxide + Zinc Oxides. All TiZO products are reef-friendly and 100% free of chemical sunscreens, dyes, fragrances, gluten, phthalates, and parabens.  TiZO Photoceutical Skincare is the perfect partner to our sunscreens in the fight against photoaging. These silky, elegant products address tone, texture and hydration while helping to prevent further damage. From our flagship TiZO3 Primer/Sunscreen SPF 40 to our gentle Ultra Zinc formulations to our NEW Advanced Vitamin C+E Serum with Bakuchiol, TIZO has the ideal selection of products to Protect, Repair, and Revitalize skin.    Website: https://tizoskin.com/  Facebook: @tizoskin  Pinterest: @tizoskin  Instagram: @tizoskin  YouTube: @tizoskin     Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

Jeff Grubb is joined by Mat Piscatella to talk about July's US video game market highlights report from Circana, Kirby's Switch 2 update and expansion getting glowing reviews, and naturally, development troubles across the industry.Today's episode is brought to you by our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

We're packed with video game talk this week as we talk about Metal Gear Solid Delta, Dan's time with Chibi-Robo, Jan's Gamescom preview of Onimusha, Pragmata, and Resident Evil Requiem, Grubb nearing the end of Expedition 33, and how great Shinobi: Art of Vengeance is! We also recap other Gamescom stories, the delays that Silk Song is causing, and more!Today's episode is brought to you by our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

Deze talkshow wordt mede mogelijk gemaakt door MSI monitoren. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.We hebben eindelijk een weekend echt goed kunnen uitslapen. Drenthe, Castlefest, Lowlands en Gamescom zijn allemaal achter de rug. Fris en fruitig zitten Boris, Jasper en Skate daarom achter de desk om jullie een nieuwe editie van Brievenmaandag te brengen. De rubriek waarin we de prangende vragen van de community naar eer en geweten beantwoorden. Vragen zijn er altijd genoeg. Dit keer behandelen de drie vragen over een nieuwe Castlevania en Bloodborne, de standaard vraag voor advies over nieuwe TV en de waarde van een ticket voor de media-dag van Gamescom. De antwoorden op deze en andere vragen krijg je in de Brievenmaandag van maandag 25 augustus.Komt er wel of niet nog een tweede deel van Bloodborne?Als Skate bij Brievenmaandag zit, dan weet je dat er zeker één vraag over een soulslike game bij zit. Dat is nu ook het geval. Iemand wil weten of er ooit nog een tweede deel van Bloodborne komt? Een andere briefschrijver wil weten waarom de ene game weinig data op je harde schijf parkeert, terwijl de andere de boel helemaal vol stouwt. Plus, wat er in het pakketje dat speciaal gericht is aan Skate? Je ziet het in deze video.Check de krachtige gaming monitoren van MSIDat MSI goede laptops en PC's maakt voor gamers weten we inmiddels allemaal, maar ook hun monitoren zorgen voor prima prestaties. Neem bijvoorbeeld de 272URX QD OLED. Een monitor met een 2.1 display port, een OLED scherm (+ OLED care + 3 jaar garantie), 4K power en een responsetijd van 240 Hz + 0.03 ms. Dat is fijn gamen. Wil je meer informatie over dit scherm, dan kun je hier terecht.

Get the transparency you deserve and make sure you see the whole story with Ground News. Subscribe to their Vantage plan today and save 40% with our link: https://ground.news/WAN Cool down your PC in style! Check out MSI's MPG CORELIQUID P13 AIO at https://lmg.gg/7UjMo Step confidently into daily life with the ultra-light Vessi Sneakers. Vessi claims they are fully waterproof, and they come with a 1-year warranty with 30-days of worry-free returns. Get 15% off your first pair at https://vessi.com/wanshow at checkout! Get a Circuit Board skin for your device so dbrand can keep messing with Linus at https://dbrand.com/pcb Check out Dell's powerful business laptops at: https://lmg.gg/dellprowan Pick up a Secretlab Titan Evo Ergonomic Gaming Chair today at: https://lmg.gg/secretlabwan Get a special deal on Private Internet Access VPN today at https://www.piavpn.com/LinusWan Purchases made through some store links may provide some compensation to Linus Media Group. NewYork Times Article: https://www.nytimes.com/2025/08/17/business/tiktok-ai-avatars.html Learn more about your ad choices. Visit megaphone.fm/adchoices

Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site.Na anderhalve week on the road te zijn geweest, zitten we eindelijk in de oude, vertrouwde studio. Huey en Koos hebben een paar uur kunnen slapen in hun eigen bed en zijn klaar om jullie een verse editie van Einde van de Week Live te presenteren. De talkshow waarin we wekelijks het belangrijkste game gerelateerde nieuws met jullie doornemen. En reken maar dat er genoeg te vertellen valt na twee dagen Gamescom. Er is een hoop gebeurd. Welke vette games hebben de heren gezien? Wat was het hoogte- en wat het dieptepunt? What up met de haat richting Call of Duty Black Ops 7, de immense hype rond Silksong en de dramatische framerate van Elden Ring? Deze onderwerpen en veel meer ga je meemaken in de Einde van de Week Live van vrijdag 22 augustus 2025.Haat voor Call of Duty Black Ops 7, liefde voor Hollow Knight SilksongMaar er is meer. Zo steeg de PS5 met 50 dollar in prijs. Gaat deze prijsstijging, die eerder ook in de EU plaatsvond, de doorverkoop van de console van Sony in de weg zitten? En komt Valve nu toch met een eigen console? Het antwoord op al deze vragen krijg je in deze video.Pak 150 fijne euro korting op de krachtige Katana 15 HC gaming laptopMSI zet vandaag de Katana 15 HX in het zonnetje. Met onder de motorkap een 14e generatie i7 processor, een RTX 5060 GPU, een 512 GB SSD, 144Hz Full HD paneel en een 4-zone RGB toetsenbord. Deze gaming laptop is nu hier met 150 euro korting aan te schaffen bij Bol.com.Scoor fijne kortingen op de gaming monitoren van AOCWe hebben de laatste tijd al heel wat verschillende brands monitoren voorbij zien komen. Vandaag presenteren we het volgende merk wat haar gear graag aan de Gamekings community wil presenteren: AOC. Het Taiwanese AOC heeft twee lijnen voor gamers klaarstaan. AOC Gaming combineert kwaliteit met betaalbare prijzen. Denk aan monitoren met hoge refresh rates, lagere resolutie en gewone lcd-panelen, tegen een scherpe prijs. De AGON PRO-lijn focust zich op de high-end markt, met (QD)-OLED, 1440P/4K en hoge refresh rates. Perfect voor fanatieke gamers die bereid zijn wat meer geld uit te geven aan een monitor. Wil je meer info of gebruikmaken van leuke kortingen op de AOC monitoren, check dan de linkjes naar Bol en Coolblue in de tekst bij de video.Kom langs op het Elder Scrolls Online community event van Bethesda in UtrechtFan van Elder Scrolls Online en zin in een feestje? Zondag 31 augustus in Bar Josefien in Utrecht vindt er een ESO-community event plaats vanaf 18:30 uur. Gratis entree en free drinks en snacks on the house. Plus give aways, Q&A's, Trivia en de bekende gezelligheid die je van Tamriel kent. Interesse, je kunt aanmelden door te mailen naar community_blx@bethsoft.com .Timestamps:00:00:00 Einde van de Week Live van 21 augustus00:00:23 Huishoudelijke mededeling: MSI00:02:23 Hoe is de Gamescom bevallen als event?00:11:25 Dit zijn genomineerden voor de Gamescom Awards.00:16:10 Silent Hill f toonde een nieuwe trailer tijdens Gamescom. 00:18:17 Hollow Knight Silksong was een van de grote hits op de beursvloer.00:20:23 Wat is dat met de immense haat die Call of Duty Black Ops 7 momenteel treft? 00:22:37 De PS5 is 50 dollar in prijs gestegen in de VS. 00:25:05 Elden Ring draait dramatisch op Switch 2. 00:27:07 BULLETTÎME: AOC00:30:50 Hell Let Loose: Vietnam 00:34:13 Gerucht. Toch de console van Valve? 00:36:47 ROG Xbox Ally X 16 oktober, nog geen prijs bekend. 00:41:28 Bungie CEO Pete Parsons na 23 jaar bij Bungie weg.00:46:03 Grappig. Op de Gamescom (Opening Night) werd de nieuwe Wukong aangekondigd. Als je denkt dat we er dan zijn, vergeet het maar…00:48:04 Forza Horizon 6 zou zich wel eens af kunnen spelen in Japan.00:49:50 BULLETTÎME: The Elder Scrolls Online event 00:51:33 Cool of Serious Uncool?

Esportmaníacos 2357: En el programa de hoy hemos hablado de los problemas que tuvo G2 en el MSI ya que los ha desvelado BrokenBlade en una entrevista. También hemos visto que Mac ha hablado de su posible despido por el anuncio que hizo Neo hace unos meses. Finalmente, hemos hablado de nuestras sorpresa y decepciones de la LEC. APÓYANOS AQUÍ https://www.patreon.com/Esportmaniacos https://www.twitch.tv/esportmaniacos 🔁Nuestras redes🔁 https://twitter.com/Esportmaniacos https://www.tiktok.com/@esportmaniacos 💙Referido de AMAZON: https://amzn.to/36cVx3g 00:00:00 - Intro 00:15:30 - Partidos destacados del fin de semana 00:25:40 - El posible despido de Mac 00:39:39 - Los problemas de G2 en el MSI 01:04:50 - Llega MFreak 01:07:30 - Sorpresas y decepciones de la LEC 01:39:35 - Resumen de Superliga Domino's

What if that breakout isn't just hormonal—and that redness isn't rosacea? In this episode of ASCP Esty Talk, we discuss how big emotions like grief and anger can sneak onto the skin and masquerade as everyday conditions. You'll learn how to spot the difference, what to skip in the treatment room (hint: put down the glycolic), and how to build treatments that meet your clients where they really are—emotionally and physiologically. Plus, we're giving you home-care ideas that go way beyond “use this serum.” This one's for the esties ready to treat more than what meets the eye. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE   TiZO Mineral Sunscreens set the standard for aesthetic elegance with tinted and non-tinted formulas for use on virtually all skin types and tones. Our name reflects our commitment: TIZO = Titanium dioxide + Zinc Oxides. All TiZO products are reef-friendly and 100% free of chemical sunscreens, dyes, fragrances, gluten, phthalates, and parabens.  TiZO Photoceutical Skincare is the perfect partner to our sunscreens in the fight against photoaging. These silky, elegant products address tone, texture and hydration while helping to prevent further damage. From our flagship TiZO3 Primer/Sunscreen SPF 40 to our gentle Ultra Zinc formulations to our NEW Advanced Vitamin C+E Serum with Bakuchiol, TIZO has the ideal selection of products to Protect, Repair, and Revitalize skin.    Website: https://tizoskin.com/  Facebook: @tizoskin  Pinterest: @tizoskin  Instagram: @tizoskin  YouTube: @tizoskin     Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

Esportmaníacos 2355: Hoy hemos tenido programa movidito porque ha habido varias declaraciones de entrevistas a jugadores de la LEC que han salido estos días. Primero veremos las declaraciones de Myrwn sobre cómo se adapta él a los torneos internacionales después de su primera experiencia en Worlds. Después las de Mikyx, en las cuales habla de la liga en general pero también de Fnatic en particular. Finalmente hemos tocado las palabras de Brokenblade sobre los cambios internos en G2 después del fatídico MSI jugado por los samurais. APÓYANOS AQUÍ https://www.patreon.com/Esportmaniacos https://www.twitch.tv/esportmaniacos 🔁Nuestras redes🔁 https://twitter.com/Esportmaniacos https://www.tiktok.com/@esportmaniacos 💙Referido de AMAZON: https://amzn.to/36cVx3g 00:00:00 - Intro 00:18:25 - Repaso de la LCK 00:33:40 - Myrwn y su nuevo enfoque para los internacionales 01:01:45 - Mikyx habla de FNC y de la LEC en general 01:33:00 - Brokenblade explica los cambios internos en G2 01:48:30 - KOI Fenix eliminado de Superliga

We're back and we're early today! We chat about Grubb starting Expedition 33, Raccoin Pusher, a couple of puzzles with Is This Seat Taken? and Voxelgram 2, and a bunch more games. We also chat about Bioshock 4, an actual Silksong announcement, and other news before Gamescom. Oh...and somehow we talk about War of the Worlds for a while....Today's episode is brought to you by our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

Jeff Grubb is joined by Seth Macy to start your week right, chatting about the fate of Fairgame$, Skate 4 having a rotating soundtrack, and a MASSIVE Kirby Air Riders Direct happening very soon.Today's episode is brought to you by our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

I sit down with Dr Magali Svrcek, Professor of Pathology at the University of Sorbonne in Paris, and she discusses her role as a GI Pathologist.  Dr Svrcek discusses Microsatellite Instability, digital tools and Immunohistochemistry.  Dr Svrcek wrote her script in English, so I in turn wrote my introduction and closing en Francais.  I hope my French is ok.  With fewer Pathologists, especially internationally, digital pathology could be a solution.  In working with Owkin, the collaboration, MsIntuit, an AI diagnostic tool to detect MSI, and is the first to be CE marked.   Colorectal cancer is experiencing an increase internationally as western lifestyle spreads.  African countries, especially sub-Saharan African countries will not have the tools or infrastructure to work with this increase.  Developing a network of experts using digital pathology could mitigate some of these issues.  

BUFFALO, NY – August 15, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on August 13, 2025, titled “Clinical and analytical validation of MI Cancer Seek®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay.” In this study, first authors Valeriy Domenyuk and Kasey Benson, along with corresponding author David Spetzler from Caris Life Sciences in Irving, Texas, introduce MI Cancer Seek, an FDA-approved test designed to deliver comprehensive tumor profiling. MI Cancer Seek demonstrated strong concordance with other FDA-approved companion diagnostics and serves as a powerful tool to guide treatment decisions in both adult and pediatric cancer patients. Cancer remains one of the most complex and diverse diseases to treat. With many targeted therapies currently FDA-approved, selecting the right one for a specific patient requires detailed genetic insights. MI Cancer Seek addresses this need by analyzing both DNA and RNA from a single tumor sample. The tool identifies key biomarkers linked to FDA-approved treatments for several major cancers, including breast, lung, colon, melanoma, and endometrial cancers. One of the most significant strengths of MI Cancer Seek is its ability to deliver accurate and reliable results from minimal tissue input (50 ng). Even when analyzing formalin-fixed paraffin-embedded samples, which are widely used but often degraded, the test maintained high levels of accuracy. It successfully detected important genetic alterations such as PIK3CA, EGFR, BRAF, and KRAS/NRAS mutations and measured tumor mutational burden (TMB) and microsatellite instability (MSI), both of which are key indicators for immunotherapy response. In clinical comparisons, the test achieved over 97% agreement with other FDA-approved diagnostic tools, confirming its reliability in detecting critical biomarkers. Notably, it showed near-perfect accuracy in identifying MSI status in colorectal and endometrial cancers. The researchers also demonstrated that the test maintains precision across different lab conditions and varying DNA input levels, confirming its robustness for routine clinical use. Beyond its role as a companion diagnostic, MI Cancer Seek incorporates additional features developed under its predecessor, MI Tumor Seek Hybrid. These include detection of homologous recombination deficiency, structural variants, and cancer-related viruses. It also includes advanced tools such as the Genomic Probability Score for identifying the tissue of origin in cancers of unknown primary, as well as a gene signature to guide first-line chemotherapy in colorectal cancer. “One limitation to be considered is the low PPA for ERBB2 CNA detection.” By offering deeper genetic insights from a single, small sample, MI Cancer Seek has the potential to streamline diagnostics, reduce testing costs, and connect patients to effective therapies more quickly. As precision medicine continues to expand, this assay stands out as a comprehensive and efficient solution for meeting the evolving needs of modern oncology. DOI - https://doi.org/10.18632/oncotarget.28761 Correspondence to - David Spetzler - dspetzler@carisls.com Video short - https://www.youtube.com/watch?v=D4hd2FxCYY8 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Jeff Grubb and TurboShawn are here to end your week with updates on Pokemon Legends Z-A, Sakurai insisting we will see Kirby Air Riders footage soon, headaches with using PayPal on Steam, Call of Duty: Black Ops 7 not being on Switch 2 at launch, a rumor of the next Resident Evil remakes, and more! Today kicks off our month-long partnership with our friends at MSI!For the next month, they'll be offering the Giant Bomb community 10% off regularly priced Intel B860/Z890 motherboards at their US Store: https://us-store.msi.com/ - Just use code "bombcast" at checkout!Big thanks to MSI for their support!

Skin care has been the reigning queen of beauty for years—but that crown may be slipping. Is this just a phase or a sign that consumer behavior is evolving? In this episode of ASCP Esty Talk, Maggie and Ella unpack the so-called “skin care recession,” a major industry shift showing a slowdown in skin care sales and a rise in fragrance and makeup. Tune in as we explore what's driving the trend, how it's showing up in the treatment room, and what estheticians need to know to stay ahead. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE   TiZO Mineral Sunscreens set the standard for aesthetic elegance with tinted and non-tinted formulas for use on virtually all skin types and tones. Our name reflects our commitment: TIZO = Titanium dioxide + Zinc Oxides. All TiZO products are reef-friendly and 100% free of chemical sunscreens, dyes, fragrances, gluten, phthalates, and parabens.  TiZO Photoceutical Skincare is the perfect partner to our sunscreens in the fight against photoaging. These silky, elegant products address tone, texture and hydration while helping to prevent further damage. From our flagship TiZO3 Primer/Sunscreen SPF 40 to our gentle Ultra Zinc formulations to our NEW Advanced Vitamin C+E Serum with Bakuchiol, TIZO has the ideal selection of products to Protect, Repair, and Revitalize skin.    Website: https://tizoskin.com/  Facebook: @tizoskin  Pinterest: @tizoskin  Instagram: @tizoskin  YouTube: @tizoskin     Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare 

We zitten deze hele week in Drenthe. Op Chateau Dolmen om precies te zijn. We gaan daar bloedhete, dampende en hardcore zomerse content voor jullie maken. Gewoon omdat het kan. Eén van de onderdelen van het zomerkamp is een dagelijkse avondshow die je hier kunt gaan kijken: Chateau Dolmen: Soirée Drenthée (https://www.gamekings.tv/videos/chateau-dolmen-soiree-drenthee-nerden-op-het-platteland/). Anderhalf uur lang nerden vanuit  een weiland in Drenthe. Met Gamekings die schilderen, eten koken en Drents dialect uitproberen. Kan toch op niets anders uitlopen dan een heerlijke anderhalf uur aan vermaak.Anderhalf uur nerden in het rustieke platteland rond Chateau DolmenShelly en JJ zijn in deze aflevering te gast bij kasteelheer Jelle De l'Art. Alleen hij kan de meest persoonlijke ontboezemingen aan de heren ontlokken. Pak dus lekker een biertje en ga genieten van dit zomers spektakel.Pak 70 euro korting op de 27-inch UHD Nano IPS monitor van LG UltraGearLG UltraGear heeft een toffe actie exclusief voor de Gamekings community opgezet. De 27-inch UHD 4K (3840×2160) Nano IPS Black display is met een korting van ruim 70 euro verkrijgbaar voor onze community. Dit model is de eerste 27-inch gamingmonitor ter wereld met 4K-resolutie en 240Hz refreshrate en biedt daarmee in onze ogen een erg wrede en soepele spelervaring voor gamers, vooral voor liefhebbers van FPS-titels. Interesse, vul dan hier bij aankoop de code ‘gamekings' in het vakje bij vouchers.Scoor 25% korting bij de aankoop van de Hue starterskit + 1 accessoireDe setting van de avondshow en afterparty (terugkijken of Twitch of YouTube Live) wordt vol in de kleurige spotligfhts gezet door Philips Hue. Elke avond veranderen we daarmee de vibe bij de Soirée Drenthée. Wil je checken hoe Philips Hue jouw woning kan opfleuren. Er is 25% korting bij de aankoop van de starterskit + 1 accessoire. Hier tref je alle info aan.Pak fijne korting tijdens de Back to School actie van MSI en AzertyTerwijl we chill aan de BBQ in Drenthe zitten, is het bij MSI en Azerty volle bak Back to School. Talloze laptops verkrijgbaar voor mooie en scherpe prijzen. Alle laptops die verkrijgbaar zijn tijdens de Back to School actie zijn via de volgende link te bekijken en kopen: https://azerty.nl/sale/back-to-school?ae-categorie%5B0%5D=Laptops&merk%5B0%5D=MSI

We zitten deze hele week in Drenthe. Op Chateau Dolmen om precies te zijn. We gaan daar bloedhete, dampende en hardcore zomerse content voor jullie maken. Gewoon omdat het kan. Eén van de onderdelen van het zomerkamp is een dagelijkse avondshow die je hier kunt gaan kijken: Chateau Dolmen: Soirée Drenthée. Anderhalf uur lang hoogstaande game- en nerd-talk vanuit een blokhut in Drenthe. Met Gamekings die schilderen, eten koken en Drents dialect uitproberen. Kan toch op niets anders uitlopen dan een heerlijke anderhalf uur aan vermaak.Anderhalf uur nerden in het rustieke platteland rond Chateau DolmenBoris en Jasper zijn in deze aflevering te gast bij de kasteelheer Jelle De l'Art. Alleen hij kan de meest persoonlijke ontboezemingen aan de heren ontlokken. Pak dus lekker een biertje en ga genieten van dit zomers spektakel.Pak 70 euro korting op de 27-inch UHD Nano IPS monitor van LG UltraGearLG UltraGear heeft een toffe actie exclusief voor de Gamekings community opgezet. De 27-inch UHD 4K (3840×2160) Nano IPS Black display is met een korting van ruim 70 euro verkrijgbaar voor onze community. Dit model is de eerste 27-inch gamingmonitor ter wereld met 4K-resolutie en 240Hz refreshrate en biedt daarmee in onze ogen een erg wrede en soepele spelervaring voor gamers, vooral voor liefhebbers van FPS-titels. Interesse, vul dan hier bij aankoop de code ‘gamekings' in het vakje bij vouchers.Scoor 25% korting bij de aankoop van de Hue starterskit + 1 accessoireDe setting van de avondshow en afterparty (terugkijken of Twitch of YouTube Live) wordt vol in de kleurige spotligfhts gezet door Philips Hue. Elke avond veranderen we daarmee de vibe bij de Soirée Drenthée. Wil je checken hoe Philips Hue jouw woning kan opfleuren. Er is 25% korting bij de aankoop van de starterskit + 1 accessoire. Hier tref je alle info aan.Pak fijne korting tijdens de Back to School actie van MSI en AzertyTerwijl we chill aan de BBQ in Drenthe zitten, is het bij MSI en Azerty volle bak Back to School. Talloze laptops verkrijgbaar voor mooie prijzen. Bijvoorbeeld de Katana 15 HX B14WFK-046NL. Met aan boord een 14e generatie i7 processor, een RTX 5060 videokaart, een 1TB SSD, een 144Hz Full HD scherm en een 4-zone RGB toetsenbord. Hier kun je alle laptops die verkrijgbaar zijn tijdens de Back to School actie bekijken en kopen.

What happens when your business starts to feel like your whole identity? When you are your brand, where's the line between personal and professional? In this episode of ASCP Esty Talk, Maggie and Ella talk about the overlap between who you are and what you do—and when that overlap becomes too much, how to set boundaries and reconnect with yourself outside the treatment room. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services. Website: www.lamprobe.com Email: info@lamskin.com Phone: 877-760-2722 Instagram: www.instagram.com/lamprobe Facebook: www.facebook.com/theLAMPROBE   TiZO Mineral Sunscreens set the standard for aesthetic elegance with tinted and non-tinted formulas for use on virtually all skin types and tones. Our name reflects our commitment: TIZO = Titanium dioxide + Zinc Oxides. All TiZO products are reef-friendly and 100% free of chemical sunscreens, dyes, fragrances, gluten, phthalates, and parabens.  TiZO Photoceutical Skincare is the perfect partner to our sunscreens in the fight against photoaging. These silky, elegant products address tone, texture and hydration while helping to prevent further damage. From our flagship TiZO3 Primer/Sunscreen SPF 40 to our gentle Ultra Zinc formulations to our NEW Advanced Vitamin C+E Serum with Bakuchiol, TIZO has the ideal selection of products to Protect, Repair, and Revitalize skin.    Website: https://tizoskin.com/  Facebook: @tizoskin  Pinterest: @tizoskin  Instagram: @tizoskin  YouTube: @tizoskin     Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

“Colorectal cancer treatment is not just about eliminating a disease. It's about preserving life quality and empowering patients through every phase. So I think nurses are really at the forefront that we can do that in the oncology nursing space. So from early detection to survivorship, the journey is deeply personal. Precision medicine, compassionate care, and informed decision-making are reshaping outcomes. Treatment's just not about protocols. It's about people,” ONS member Kris Mathey, DNP, APRN-CNP, AOCNP®, gastrointestinal medical oncology nurse practitioner at The James Cancer Hospital of The Ohio State University Wexner Medical Center in Columbus, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about colorectal cancer treatment.  Music Credit: “Fireflies and Stardust” by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 1.0 contact hour of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by August 1, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learner will report an increase in knowledge related to the treatment of colorectal cancer. Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Episode 370: Colorectal Cancer Screening, Early Detection, and Disparities Episode 153: Metastatic Colorectal Cancer Has More Treatment Options Than Ever Before ONS Voice articles: Colorectal Cancer Prevention, Screening, Treatment, and Survivorship Recommendations Genetic Disorder Reference Sheet: Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) How Liquid Biopsies Are Used in Cancer Treatment Selection Oncology Drug Reference Sheet: 5-Fluorouracil Oncology Drug Reference Sheet: Oxaliplatin What Is a Liquid Biopsy? Clinical Journal of Oncology Nursing article: Colorectal Cancer in Young Adults: Considerations for Oncology Nurses Oncology Nursing Forum article: Neurotoxic Side Effects Early in the Oxaliplatin Treatment Period in Patients With Colorectal Cancer ONS Colorectal Cancer Learning Library ONS Biomarker Database (filtered by colorectal cancer) ONS Peripheral Neuropathy Symptom Interventions American Cancer Society colorectal cancer resources CancerCare Colorectal Cancer Alliance Colorectal Cancer Resource and Action Network Fight Colorectal Cancer National Comprehensive Cancer Network To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode “Colorectal cancer has several different types, but there is one that dominates the landscape, and that is adenocarcinoma. So I think most of us have heard that. It's fairly common, and it accounts for about 95% of all colorectal cancers. It begins in the glandular cells lining the colon or rectum and often develops from polyps, in particular adenomatous polyps.” TS 1:41 “One of the biomarkers that we'll most commonly hear about is KRAS or NRAS mutations. This indicates tumor genetics, and these mutations suggest resistance to our EGFR inhibitors such as cetuximab. BRAF mutation or V600E is a more aggressive tumor subtype, and those may respond to our BRAF targeted therapy. … And then our MSI-high or MMR-deficient—microsatellite instability or mismatch repair deficiency—that really predicts an immunotherapy response and may indicate Lynch syndrome, which is a huge genetic component that takes a whole other level of counseling and genetic testing with our patients as well.” TS 6:02 “Polypectomy or a local excision—that removes our small tumors or polyps during that colonoscopy. And that's what's used for those stage 0 or early stage I cancers. A colectomy removes part or all of the colon. This may be open or laparoscopic. It can include a hemicolectomy, a segmental resection, or a total colectomy, so where you take out the entire part of the colon. A proctectomy removes part or all of the rectum. This may include a low anterior resection, also known as an LAR … or an abdominal perineal resection, which is an APR. … Colostomy or ileostomy—that diverts the stool to an external bag via stoma. Sometimes this is temporary or permanent depending on the type of surgery.” TS 14:11 “We'll have our patients say, ‘Hey, I want immunotherapy therapy. I see commercials on it that it works so well.' We have to make sure that these patients are good candidates for it, also that we're treating them adequately. We need to make sure that they have those biomarkers, so as I mentioned, the MSI-high or MMR tumors. Our MSS-stable tumors—they may benefit from newer combinations or clinical trials. Metastatic disease—immunotherapy may be used alone or with other treatments. And then in the neoadjuvant setting, some trials are really showing promising results using immunotherapy prior to surgery.” TS 25:38 “Antibody-drug conjugates are really an exciting frontier in all cancer treatments as well as colorectal cancer treatment. This is used mainly for patients with advanced or treatment-resistant disease, and these therapies combine the targeted power of monoclonal antibodies with the cell-killing ability of potent chemotherapy agents. They're still on the horizon for the most part in colorectal cancer. However, there is only one approved antibody-drug conjugate, or ADC, at this time, and that's trastuzumab deruxtecan, or Enhertu. That's approved for any solid tumor, such as colorectal cancer with HER2 IHC 3+. So again, looking back at that pathology in those markers, making sure that you have that HER2 mutation and that IHC.” TS 35:00 “There are a few myths going around about colorectal cancer treatment that can lead to confusion or even delayed care. One myth is only older men get colorectal cancer. As you heard me talk in my previous podcast on screening, unfortunately, this isn't necessarily true. Colorectal cancer affects both men and women and our cases in the younger population are rising. So our screening guidelines have changed to age 45 because we are seeing it in the younger population.” TS 45:54

Will Parker is the founder and formulator of Parker Williams Skincare, a brand dedicated to simple, sophisticated skin care solutions for men. In this episode of ASCP Esty Talk, Maggie and Ella sit down with Will to learn about his pivot into skin care and the inspiration behind creating products tailored specifically for men. They explore his journey, formulation philosophy, and approach to creating effective, uncomplicated skin care. About Will Parker: Will Parker is the founder and formulator of Parker Williams Skincare, a men's skincare line focused on simplicity and performance. His work centers on creating effective, easy-to-use products that make skincare more accessible and approachable for men. Before launching his own brand, Will was the co-founder of Color Up, a wellness-focused skincare company where he led product development. His formulations earned over 20 industry awards, establishing him as a respected innovator in the field. Today, Will continues to share his expertise in skincare and product development through his work and online presence at @with_will_and_wonder and @parkerwilliamsskincare ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE   TiZO Mineral Sunscreens set the standard for aesthetic elegance with tinted and non-tinted formulas for use on virtually all skin types and tones. Our name reflects our commitment: TIZO = Titanium dioxide + Zinc Oxides. All TiZO products are reef-friendly and 100% free of chemical sunscreens, dyes, fragrances, gluten, phthalates, and parabens.  TiZO Photoceutical Skincare is the perfect partner to our sunscreens in the fight against photoaging. These silky, elegant products address tone, texture and hydration while helping to prevent further damage. From our flagship TiZO3 Primer/Sunscreen SPF 40 to our gentle Ultra Zinc formulations to our NEW Advanced Vitamin C+E Serum with Bakuchiol, TIZO has the ideal selection of products to Protect, Repair, and Revitalize skin.    Website: https://tizoskin.com/  Facebook: @tizoskin  Pinterest: @tizoskin  Instagram: @tizoskin  YouTube: @tizoskin     Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

In this episode of ASCP Esty Talk, Ella and Maggie introduce the concept of biohacking for the skin—breaking down how wellness trends like adaptogens, red light therapy, collagen supplements, and even intermittent fasting are woven into esthetics practices. Whether you're new to the term or already using these tools, this episode helps connect the dots between modern biohacking and everyday esthetics treatments. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE   TiZO Mineral Sunscreens set the standard for aesthetic elegance with tinted and non-tinted formulas for use on virtually all skin types and tones. Our name reflects our commitment: TIZO = Titanium dioxide + Zinc Oxides. All TiZO products are reef-friendly and 100% free of chemical sunscreens, dyes, fragrances, gluten, phthalates, and parabens.  TiZO Photoceutical Skincare is the perfect partner to our sunscreens in the fight against photoaging. These silky, elegant products address tone, texture and hydration while helping to prevent further damage. From our flagship TiZO3 Primer/Sunscreen SPF 40 to our gentle Ultra Zinc formulations to our NEW Advanced Vitamin C+E Serum with Bakuchiol, TIZO has the ideal selection of products to Protect, Repair, and Revitalize skin.    Website: https://tizoskin.com/  Facebook: @tizoskin  Pinterest: @tizoskin  Instagram: @tizoskin  YouTube: @tizoskin     Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

Timestamps: 0:00 y'know how computers do stuff? 0:17 YouTube, Meta's slop crackdown 2:03 Grok govt contract, Companions 3:08 Steam game bans, Reddit age checks 4:29 MSI! 5:16 LTTStore LIME Day they made me sorry 5:55 QUICK BITS INTRO 6:01 Stream Xbox games you "own" 6:32 Google can call businesses for you 7:08 China AI chip restrictions lifted 7:43 Stellantis gives up on hydrogen 8:05 YouTuber Once Were Nerd facing jail NEWS SOURCES: https://lmg.gg/9u7vB Learn more about your ad choices. Visit megaphone.fm/adchoices

The boys discuss Patch 25.14, Tilt Brackets, MSI, emails and more on episode 699 of Leaguecast! Email us - mail@leaguecastpodcast.com   Support us - https://www.patreon.com/leaguecast  Tweet us - https://twitter.com/leaguecast   Facebook - https://www.facebook.com/Leaguecast/   Join Our Discord - https://discord.gg/leaguecast  Visit our Website - https://leaguecastpodcast.com/

From managing money in the treatment room to building long-term stability, financial literacy doesn't get enough attention in the beauty industry. In this episode of ASCP Esty Talk, Maggie and Ella get real about budgeting, pricing, and everything in between. ASCP Esty Talk with hosts Ella Cressman and Maggie Staszcuk   Produced by Associated Skin Care Professionals (ASCP) for licensed estheticians, ASCP Esty Talk is a weekly podcast, hosted by licensed estheticians, Ella Cressman, ASCP Skin Deep Magazine contributor, and Maggie Staszcuk, ASCP Program Director. We see your passion, innovation, and hard work and are here to support you by providing a platform for networking, advocacy, camaraderie, and education. We aim to inspire you to ask the right questions, find your motivation, and give you the courage to have the professional skin care career you desire.  About Ella Cressman:  Ella Cressman is a licensed esthetician, certified organic formulator, business owner, ingredient junkie, and esthetic cheerleader! As an educator, she enjoys empowering other estheticians and industry professionals to understand skin care from an ingredient standpoint rather than a product-specific view.  In addition to running a skin care practice, Cressman founded a comprehensive consulting group, the HHP Collective, and has consulted for several successful skin care brands.    Connect with Ella Cressman:  Website: www.hhpcollective.com  LinkedIn: linkedin.com/in/ella-cressman-62aa46a    About Maggie Staszcuk:  Maggie Staszcuk serves as the Program Director for ASCP and is the cohost of ASCP Esty Talk podcast. With over 18 years' experience in the esthetics industry, her diverse background includes roles in spa management, spa and med-spa services, and esthetics education. Since becoming a licensed esthetician in 2006, she carries a range of certifications in basic and advanced esthetics. Maggie is dedicated to equipping estheticians with the knowledge and resources they need to thrive in their careers.   Connect with Maggie Staszcuk:  P: 800.789.0411 EXT 1636  E: MStaszcuk@ascpskincare.com    About our Sponsors:   The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE   TiZO Mineral Sunscreens set the standard for aesthetic elegance with tinted and non-tinted formulas for use on virtually all skin types and tones. Our name reflects our commitment: TIZO = Titanium dioxide + Zinc Oxides. All TiZO products are reef-friendly and 100% free of chemical sunscreens, dyes, fragrances, gluten, phthalates, and parabens.  TiZO Photoceutical Skincare is the perfect partner to our sunscreens in the fight against photoaging. These silky, elegant products address tone, texture and hydration while helping to prevent further damage. From our flagship TiZO3 Primer/Sunscreen SPF 40 to our gentle Ultra Zinc formulations to our NEW Advanced Vitamin C+E Serum with Bakuchiol, TIZO has the ideal selection of products to Protect, Repair, and Revitalize skin.    Website: https://tizoskin.com/  Facebook: @tizoskin  Pinterest: @tizoskin  Instagram: @tizoskin  YouTube: @tizoskin     Massage Envy is a national franchisor and does not independently own or operate any of the Massage Envy franchised locations nationwide. The Massage Envy franchise network, through its franchise locations, is the leading provider of massage services. Founded in 2002, Massage Envy now has approximately 1,100 franchise locations in 49 states that have together delivered more than 200 million massages and skin care services. Website: www.massageenvy.com/careers/career-areas/esthetician  Facebook: @MassageEnvyCareers LinkedIn: @MassageEnvy   About Associated Skin Care Professionals (ASCP):    Associated Skin Care Professionals (ASCP) is the nation's largest association for skin care professionals and your ONLY all-inclusive source for professional liability insurance, education, community, and career support. For estheticians at every stage of the journey, ASCP is your essential partner. Get in touch with us today if you have any questions or would like to join and become an ASCP member.  Connect with ASCP:  Website: www.ascpskincare.com  Email: getconnected@ascpskincare.com  Phone: 800-789-0411  Facebook: facebook.com/ASCPskincare  Instagram: @ascpskincare   

Thorin and Yamato discuss the final matches of MSI 2025, the reasons why GenG are the best LoL esports team, T1 and Faker's performances at the event, what it will take for Western League of Legends teams to "bridge the gap" between them and Eastern teams, Maple un-retiring to return to PSG Talon, and more! Get the ultimate immersive gaming experience with Turtle Beach today! For a limited time only, head to https://TurtleBeach.com and use Code SUMMONING for 10% off your entire order. Upgrade your wallet today! Get 10% Off Ridge with code SI at https://www.Ridge.com/SI Control Body Odor ANYWHERE with Mando and get 20% off + free shipping with promo code SUMMONING at shopmando.com! Get up to 10 FREE meals and a free item for life at https://www.hellofresh.com/lfn10fm The Last Free Nation merch shop is open! Show off your fandom and support us and by purchasing  the high-quality items on our merch shop. Check our website for more info on shipping! https://go.lastfreenation.shop/summoningyt

Welcome back to a brand new episode of The Dive Driven by Kia. Chronicler joins Azael and Kobe right after the insanity of the MSI Finals! They discuss the future of Fearless within the competitive scene, cover FlyQuest's intense series against BilliBilli Gaming, and reflect on their experience at MSI. Thank you to the fans who showed up for an epic MSI in Vancouver, and for all the listeners who tuned into these episodes!With MSI now concluded, get ready as the LTA North returns July 26th with FlyQuest taking on Disguised at 1PM PT/4PM ET, followed by Cloud9 vs Lyon.Timestamps:0:00 Intro and T1 vs Gen.G Finals Recap 21:46 Doran was not the problem27:29 FlyQuest vs BiliBili Gaming42:52 MSI Memories & Fan Appreciation

The boys discuss the ADC role, League Trivia, MSI, and more on episode 698 of Leaguecast! Email us - mail@leaguecastpodcast.com   Support us - https://www.patreon.com/leaguecast  Tweet us - https://twitter.com/leaguecast   Facebook - https://www.facebook.com/Leaguecast/   Join Our Discord - https://discord.gg/leaguecast  Visit our Website - https://leaguecastpodcast.com/

Take a look at NZXT! - https://nzxt.co/travis ( Use code: travis5 )Check out Enchanted Travel at enchantedtravel.com !Follow Travis on Twitch: http://twitch.tv/travisgaffordSupport: https://linktr.ee/tgisupport00:00:00 Intro 00:10:32 yami asks Jamada for some perspective on EU roster instability and lack of success00:38:15 Narfidy's take: FLY has to beat BLG to have a successful MSI01:00:30 NZXT break!01:03:05 rawnblade apologizes to Jamada about dismissing Fearless format concerns01:19:00 Enchanted Travel break!01:22:20 mihir's take: this MSI is the greatest international or one of01:38:20 Acklon's take: FLY is going to beat BLG in less than 5 games, CFO will beat AL in their bo5, and more01:50:49 Outro

Welcome back to a brand new episode of The Dive, Driven by Kia. MSI 2025 is already delivering some exciting games, and the crew is here to break it all down. They take a look at standout moments from every region, including an unforgettable showdown between NA and EU, an impressive showing from the LCP, and absolute bangers featuring LCK and LPL powerhouses. The team also looks ahead to Week 2's high stakes matchups, spicy storylines, and discusses which teams are heating up and which ones might be in trouble.Who's looking the strongest? Who needs to bounce back? Let us know what you think in the comments below!MSI continues July 7 at 5PM PT/8PM ET. Timestamps:0:00 - Intro & Farewell to Europe3:23 - Champion Win rates at MSI9:31 - FlyQuest vs G2 Esports Recap26:05 - Gen.G vs Anyone's Legend Recap30:37 - The Evolution of Champion Strategies44:00 - Movistar KOI vs CTBC Flying Oyster Recap46:46 - T1 vs BLG Recap1:08:59 - CTBC Flying Oyster's Impressive Showing 1:17:43 - CTBC Flying Oysters vs Anyone's Legend Preview1:29:57 - FlyQuest vs BiliBili Gaming Preview1:37:42 - Gen.G vs T1 Preview

The boys discuss LoL Stats, TFT, Fun ‘Umm Actually League Games', MSI, and more on episode 697 of Leaguecast! Email us - mail@leaguecastpodcast.com   Support us - https://www.patreon.com/leaguecast  Tweet us - https://twitter.com/leaguecast   Facebook - https://www.facebook.com/Leaguecast/   Join Our Discord - https://discord.gg/leaguecast  Visit our Website - https://leaguecastpodcast.com/  

Welcome back to The Dive Driven by Kia! Hot off the intense last day of MSI Play-Ins, Azael, Kobe, & Meteos break down all the action from the first 3 days and share how their MSI experience has been so far. With the Bracket Stage just around the corner, the crew look ahead at the exciting matchups, key players, and storylines to keep an eye on.The MSI Bracket Stage begins July 1st at 5:00pm PT/8:00pm ET as Gen.G takes on G2 Esports.Timestamps:0:00 - Intro & Initial Play-Ins Thoughts3:25 - FURIA MSI Performance8:30 - GAM vs G228:10 - BiliBili Gaming Domination32:06 - Bracket Stage Matchup Previews - G2 vs Gen.G 37:47 - FlyQuest vs Anyone's Legend45:59 - Movistar KOI vs BiliBili Gaming52:00 - CTBC Flying Oysters vs T1

Welcome back to The Dive Driven by Kia! In this episode, Kobe and Meteos are joined by Emily Rand and Riot Cadmus, Modes Lead, to discuss all the changes coming to ARAM. Then, the crew breaks down Patch 25.13 (the MSI patch) and previews all the teams facing off in Vancouver.Timestamps:0:00 - Intro with Modes Lead Producer Riot Cadmus2:43 - ARAM Changes9:26 - ARAM Champion Buffs13:44 - Brawl, Arena, Swarm, Dominion & Twisted Treeline19:54 - ARAM All Time Teams25:10 - Exhaust in ARAM29:18 - MSI Meta Predictions & Patch 25.13 42:49 - Movistar KOI's Rise to 1st Seed  50:00 - BiliBili Gaming & Anyone's Legend1:01:49 - Gen. G & T11:08:11 - G2 Esports Expectations  1:09:50 - FURIA & GAM Esports 1:31:11 - CTBC Flying Oysters1:18:31 - FlyQuest 

The boys discuss Patch 25.13, Yunara, MSI, EWC, and more on episode 696 of Leaguecast! Email us - mail@leaguecastpodcast.com   Support us - https://www.patreon.com/leaguecast  Tweet us - https://twitter.com/leaguecast   Facebook - https://www.facebook.com/Leaguecast/   Join Our Discord - https://discord.gg/leaguecast  Visit our Website - https://leaguecastpodcast.com/