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Best podcasts about MSI

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Latest podcast episodes about MSI

ASCO Guidelines Podcast Series
Biomarkers for Systemic Therapy in Metastatic Breast Cancer Guideline Update

ASCO Guidelines Podcast Series

Play Episode Listen Later Jun 27, 2022 15:29


An interview with Dr. Lynn Henry from the University of Michigan in Ann Arbor, MI, lead author on "Biomarkers for Systemic Therapy in Metastatic Breast Cancer: ASCO Guideline Update." Dr. Henry reviews new biomarkers for the purposes of making treatment decisions for triple-negative breast cancer, and hormone receptor-positive, HER2-negative breast cancer, as well as tumor agnostic tumor biomarkers. Specific biomarkers addressed in this conversation include PIK3CA, ESR1, BRCA 1/2, PALB2, HRD, PD-L1, dMMR/MSI-H, TMB, NTRK, ctDNA, and CTCs. Read the full guideline at www.asco.org/breast-cancer-guidelines.   TRANSCRIPT Brittany Harvey: Hello and welcome to the ASCO Guidelines Podcast series, brought to you by the ASCO Podcast Network, a collection of nine programs, covering a range of educational and scientific content and offering enriching insight into the world of cancer care. You can find all the shows including this one at asco.org/podcasts. My name is Brittany Harvey and today I'm interviewing Dr. Lynn Henry from the University of Michigan in Ann Arbor, Michigan, lead author on 'Biomarkers for Systemic Therapy in Metastatic Breast Cancer: ASCO Guideline Update'. Thank you for being here, Dr. Henry. Dr. Lynn Henry: Thank you very much for inviting me to participate. Brittany Harvey: First, I'd like to note that ASCO takes great care in the development of its guidelines and ensuring that the ASCO conflict of interest policy is followed for each guideline. The full conflict of interest information for this guideline panel is available online with the publication of the guideline in the Journal of Clinical Oncology. Dr. Henry, do you have any relevant disclosures that are related to this guideline topic? Dr. Lynn Henry: No, I do not. Brittany Harvey: Great! Thank you. Then let's talk about the scope of this guideline. So, what prompted this update to the guideline on the use of biomarkers to guide decisions on systemic therapy for patients with metastatic breast cancer, which was last updated in 2015? And what is the scope of this guideline update? Dr. Lynn Henry: Yes, so a lot has happened in the past six or seven years that influence how we treat metastatic breast cancer. And there are many new drugs that have been approved by the FDA during that time. When we reviewed the prior guideline and the new treatment landscape, we realized that while much of what was included in the old guideline was still relevant, there were quite a number of new biomarkers related to new drugs that needed to be included. The newly recommended biomarkers are primarily applicable to making decisions about treatment of estrogen receptor, progesterone receptor, and HER2-negative breast cancer, also called triple-negative breast cancer, as well as for treatment of hormone receptor-positive HER2-negative breast cancer. And finally, there are now some tumor biomarkers that can be tested for that are tumor agnostic, and these were included as well. Brittany Harvey: Great! So, then let's discuss the updated guideline recommendations based off these new biomarkers for our listeners. The guideline reviews testing for several different biomarkers. So, I would like to review each of the biomarkers that the panel assessed. Let's start with what is the role of PIK3CA mutation testing? Dr. Lynn Henry: Yeah! So, PIK3CA activating mutations are commonly found in tumors that are hormone receptor-positive and HER2-negative. Based on the results of the SOLAR-1 trial, patients whose tumors have an activating PIK3CA mutation had improved progression-free survival when treated with the PI3 kinase inhibitor alpelisib plus fulvestrant compared to fulvestrant alone. This improvement was not seen in patients whose cancers didn't have a mutation. So, therefore, this provided the evidence for the clinical utility of evaluating tumors for the somatic PIK3CA mutations. Testing of either a tumor specimen or plasma to look for PIK3CA mutations can be performed. However, it's important that if the plasma is tested, and no PIK3CA mutations are identified in the circulating tumor DNA, then our tumor specimen should really be tested if possible, because of the possibility of a false negative finding in the plasma. Also, since these mutations can be acquired over time, a more recent specimen should be tested if possible, as opposed to testing the primary tumor. Finally, in the SOLAR-1 trial, a patient's tumor had to have one of the 11 pre-specified PIK3CA mutations in exon 7, 9, or 20. And therefore, when mutations are identified using next-generation sequencing, it is important to confirm that the identified mutation is one of those 11 activating mutations and not a different one that may not convey benefit from treatment with a PI3 kinase inhibitor. Brittany Harvey: Great! I appreciate you're reviewing that recommendation, as well as the clinical utility of it and the evidence behind it. So, then following those recommendations, what is the role of testing for ESR1 mutations? Dr. Lynn Henry: At this time, there are insufficient data to support routine testing of metastatic hormone receptor-positive HER2-negative tumors for ESR1 mutations. However, the panel did note that there's a retrospective analysis of two different phases three trials that demonstrated that fulvestrant improved progression-free survival compared to the aromatase inhibitor exemestane in patients who had previously progressed on a non-steroidal AI and whose tumors had an ESR1 mutation. Importantly, there are ongoing clinical trials addressing this issue, including the PADA-1 trial, which is evaluating the effect of the switch of fulvestrant from aromatase inhibitor therapy, versus remaining on that therapy when ESR1 mutations are detected in the blood. However, although preliminary findings were presented at a recent large breast cancer meeting, and were suggestive of a possible progression-free survival benefit from switching therapy, data have not yet been published, and therefore they were not included in this guideline. Brittany Harvey: Great! So, we'll look forward to those updated data to potentially review that recommendation in the future. So, following those recommendations, what is the role of testing for germline BRCA 1 or 2 and PALB2 pathogenic mutations? Dr. Lynn Henry: So, the answer for germline BRCA1 and BRCA2 mutations is relatively straightforward. Patients with metastatic HER2-negative breast cancer can be either hormone receptor-positive or negative, and who are candidates for treatment with a PARP inhibitor should undergo testing for germline BRCA1 and BRCA2 pathogenic or likely pathogenic mutations to determine whether they should receive treatment with a PARP inhibitor. This recommendation is based on the results of two large randomized clinical trials comparing PARP inhibitor therapy to physician's choice chemotherapy, although notably, the chemotherapy options did not include taxanes, anthracyclines, or platinums. In contrast, there remains insufficient evidence to support a recommendation either for or against testing for germline PALB2 pathogenic variant for the purpose of determining eligibility for treatment with a PARP inhibitor. The panel did note, however, that there are small single-arm studies that show that there is high response rate to PARP inhibitors in patients with metastatic breast cancer and coding DNA repair defects, such as either germline PALB2 pathogenic variants or somatic BRCA1 or 2 mutations. It was also noted that it is likely that patients who harbored mutations in these genes will actually be identified through routine testing with panel testing for germline variants. Brittany Harvey: Okay, understood. So, then following those recommendations, what is the role of testing tumors for homologous recombination deficiency? Dr. Lynn Henry: So, although there are emerging data from other solid tumors to support the use of homologous recombination deficiency, or HRD testing to guide therapy, current data do not support the assessment of HRD in the management of metastatic breast cancer. Therefore, we did not recommend routine testing of tumors for HRD at this time. Brittany Harvey: It's important to note where we both have evidence and where we don't have evidence. So, then what is the role of testing for expression of PD-L1 in metastatic breast cancer? Dr. Lynn Henry: So, the panel recommends that patients who are candidates for treatment with immunotherapy, with either a PD1 or PD-L1 inhibitor, should undergo testing for expression of PD-L1 in the tumor and immune cells with an FDA-approved test. At present in the United States, pembrolizumab is the only approved immunotherapy for the treatment of metastatic breast cancer, and it is given in combination with chemotherapy. The FDA-approved test for this drug is the 22C3 assay which evaluates PD-L1 staining in the tumor and surrounding stroma to calculate a combined positive score or CPS, with positive considered to be a score of 10 or greater. Of note, in other countries, there are different anti PD1 and PD-L1 antibodies that are approved for treatment, and each has been approved with its own companion diagnostic. So, it is important to make sure that you're using the right biomarker test, depending on which drug you are planning to use. Brittany Harvey: Great! I appreciate you reviewing the test in addition to the role of the biomarker. So, then, following those recommendations, what is the role of testing for deficient mismatch repair microsatellite instability-high? Dr. Lynn Henry: Similar to PD-L1 testing, it is recommended that patients with metastatic breast cancer who are candidates for a treatment regimen that includes an immune checkpoint inhibitor should undergo testing for deficient mismatch repair or microsatellite instability-high to determine eligibility for treatment with one of the drugs that is currently FDA approved, either dostarlimab or pembrolizumab. In contrast to the PD-L1 data, however, there are no randomized studies that have been conducted specifically in patients with breast cancer addressing this question. The testing recommendation was therefore included in these guidelines because of the tumor agnostic FDA approval of these drugs. In terms of which biomarker methodology to use, it was noted that, while the original studies assessed the deficient mismatch repair and MSI high using immunochemistry, and PCR respectively. The FDA has subsequently approved the next-generation sequencing platform to use in selecting candidates for these treatments. And so, therefore, there are a number of different tests that can be used. Brittany Harvey: Thank you for reviewing those recommendations as well. So, then following, what is the role of testing for tumor mutational burden? Dr. Henry Lynn: So, tumor mutational burden describes the quantity of somatic mutations in the tumor. Similar to the biomarkers we were previously discussing, there are minimal data specifically in metastatic breast cancer to support the assessment of tumor mutational burden for making treatment decisions. However, the testing recommendation was again included in the guidelines because of the tumor agnostic FDA approval of the drug pembrolizumab in the setting of high TMB. And also there is one single arm phase two trial that looked at this specifically. Importantly, the panel noted that there are a variety of factors that influence assessment of TMB. These include sample type, pre-analytical factors so how the sample was handled, the size of the panel and mutations that are tested, depths of the sequencing, type of the mutations that are included on the panel, and cut point variables. So, in particular, assessment of TMB in cell-free DNA assays such as circulating tumor DNA is an area of evolving evidence. There are therefore very important caveats to be aware of when selecting a TMB assay and assessing the results, many of which are outlined in the guideline manuscript itself, and different assays can yield different results for the same tissue specimen. It is therefore very important to use the approved companion assay and the approved cut point when making decisions regarding a specific treatment. Brittany Harvey: Absolutely. I appreciate your reviewing those details. So, then what is the role of testing for neurotrophic tyrosine receptor kinase? Dr. Lynn Henry: So, I'm going to abbreviate that to NTRK. So, NTRK fusions are rare in metastatic breast cancer. One study said 0.39% of all breast cancers have NTRK fusions. So, as with the above biomarkers, the NTRK testing recommendation is based on the results of phase 1 and phase 2 studies that were identified by the panel evaluating the efficacy and safety of these inhibitors for the treatment of advanced solid tumors with NTRK gene fusions, noting that there are only minimal data available that are specific to metastatic breast cancer. Brittany Harvey: Understood. Some of these are very rare in metastatic breast cancer. So, then, following that recommendation, what is the role of using circulating tumor DNA? Dr. Lynn Henry: So, for circulating tumor DNA, although the ctDNA technology holds promise in metastatic disease, for its ability to potentially identify tumor-specific mutations that are shed into the blood and that may be targetable, to date, neither the measurement of changes in ctDNA as a marker of treatment responsiveness nor identification of specific mutations in the blood to direct therapy has actually been prospectively shown to improve patient outcomes compared to standard imaging-based detection of tumor progression. Therefore, at present, the guideline does not recommend routine assessment of ctDNA for monitoring response to therapy among patients with metastatic breast cancer, although many studies are underway evaluating this question. Brittany Harvey: Understood. Then the last biomarker that the panel assessed in this guideline update, what is the role of using circulating tumor cells? Dr. Lynn Henry: Similar to circulating tumor DNA, there are insufficient data to recommend routine use of circulating tumor cells to monitor response to therapy among patients with metastatic breast cancer. To date, studies that have examined the clinical utility of this marker to determine the optimal time for treatment change have not led to improvements in outcomes in metastatic breast cancer. Brittany Harvey: Great! Well, thank you for reviewing all of these recommendations. The panel certainly took on a lot of biomarkers and performed a critical review of all the evidence to make recommendations in this setting. So, in your view, Dr. Henry, what is the importance of this guideline update and what should clinicians know as they implement these updated recommendations? Dr. Lynn Henry: Yeah, that's an excellent question. So, this guideline addresses the key questions that we face, as we're making decisions about how best to treat patients with metastatic breast cancer. Importantly, the guideline highlights the current state of the science, with a focus on the available published data from randomized clinical trials. It also discusses the limitations of our current knowledge, as well as key considerations for different biomarkers. Of course, we recognize that there are new data emerging on a regular basis. And the panel therefore also highlighted where data are anticipated but not yet available, as well as key questions which we hope will be able to be addressed in the more distant future. Brittany Harvey: And then finally, how will these guideline recommendations affect patients with metastatic breast cancer? Dr. Lynn Henry: Yeah, so really, that is the bottom line, isn't it? So, ideally, this guideline will enable the dissemination of best practices in terms of biomarker selection and analysis to guide clinicians as they are making treatment decisions in conjunction with patients. Treatment of metastatic breast cancer has become more complex, with regimen selection affected by both inherited germline genetics and somatic changes in the cancer that can evolve over time. The assessment of relevant biomarkers should allow patients to receive the optimal therapies that are most likely to be effective based on the individual characteristics of their cancers. Brittany Harvey: Well, I want to thank you so much for reviewing this guideline with me today, and all of the recommendations and our gaps in evidence, for our listeners. Thank you for your work on this guideline update and thank you for your time today, Dr. Henry. Dr. Lynn Henry: Thank you so much! Brittany Harvey: And thank you to all of our listeners for tuning in to the ASCO Guidelines podcast series. To read the full guideline, go to www.asco.org/breast-cancer-guidelines. You can also find many of our guidelines and interactive resources in the free ASCO guidelines app available on iTunes or the Google Play Store. If you have enjoyed what you've heard today, please rate and review the podcast and be sure to subscribe so you never miss an episode.   The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement.  

Gamekings
EvdWL over PlayStation, GamesCom, Battlefield & line-up oktober 2022

Gamekings

Play Episode Listen Later Jun 24, 2022 92:10


Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site. Dé allerbeste afsluiter van de week staat zoals elke vrijdag strak op je beeldscherm. We hebben het natuurlijk over EvdWL. Daan, Jelle & Koos zijn achter de desk gekropen en zitten klaar om de afgelopen week met jullie door te nemen. De drie gaan het hebben over het nieuws over de wens van PlayStation voor een vervolg op Ghost of Tsushima 2, Starfield, de GamesCom, het PlayStation event van komende week, Battlefield, de E3 versus Summer Game Fest en de line-up voor oktober 2022. Dit en veel meer ga je zien en horen in de de Einde van de Week Live van vrijdag 24 juni 2022. Unieke prijsvraag: wordt 1 middag onderdeel Gamekings crew Er zijn prijsvragen en prijsvragen. En deze valt in de laatste categorie. Een mogelijke droom van veel community-leden kan namelijk in vervulling gaan als je de Saints Row Boss Factory prijsvraag wint. Je maakt dan 1 middag onderdeel uit van de Gamekings crew en speelt samen met ons mee tijdens de Saints Row livestream in Utrecht. Hoe je wint? Heel simpel. Download de Boss Factory tool en creëer jouw eigen karakter. Ga all out want tijdens de EvdW Live van vrijdag 1 juli kiezen wij het vetste karakter uit. En als jij dat bent, dan spelen jij en jouw karakter mee in de stream op augustus. Hoe wreed is dat? Inzendingen kunnen gemaild worden naar redactie@gamekings.tv Nieuwe notebooks MSI in de spotlights MSI zet ook dexe week hun onlangs aangekondigde Notebooks in de spotlights. Denk aan de Titan GT77 die qua prestaties niet onder doet voor een desktop en de Raider GE67 met OLED scherm. Wil je meer informatie over deze laptops, check dan snel deze link. https://bit.ly/HX-NB

ASCP Esty Talk
EP 126 - The Rogue Pharmacist - Live from the ASCP School Forum: Designing the Best You - Healthy Mind, Body, and Skin

ASCP Esty Talk

Play Episode Listen Later Jun 24, 2022 65:40


The beauty industry encompasses businesses and services geared toward helping people look their best, but the industry is profoundly changing. People are looking past the surface to learn about systemic change and how to truly care for the skin from within. Recorded live from the ASCP Skin Care School Forum, Benjamin Knight Fuchs, RPh, discusses the future of skin health and designing the best you. This episode takes a closer look at the link between good nutrition and healthy, glowing skin. Can we turn back the hands of time just by adjusting our diet? Associated Skin Care Professionals (ASCP) presents The Rogue Pharmacist with Benjamin Knight Fuchs, R.Ph. This podcast takes an enlightening approach to supporting licensed estheticians in their pursuit to achieve results-driven skin care treatments for their clients. You can always count on us to share professional skin care education, innovative techniques, and the latest in skin science. Benjamin Knight Fuchs is a registered pharmacist, nutritionist, and skin care chemist with 35 years of experience developing pharmacy-potent skin health products for estheticians, dermatologists, and plastic surgeons. Ben's expert advice gives licensed estheticians the education and skin science to better support the skin care services performed in the treatment room while sharing insights to enhance clients' at-home skin care routines. Connect with Ben Fuchs:    Website: www.brightsideben.com    Phone: 844-236-6010    Facebook: www.facebook.com/The-Bright-Side-with-Pharmacist-Ben-Fuchs-101162801334696/    About Our Sponsor: LAMPROBE The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE  

Hot News
15 BILLION DOLLARS Down the Drain

Hot News

Play Episode Listen Later Jun 20, 2022 12:48


Sources & Timestamps! 0:00 - Intro 00:56 - $15B Of GPUs Sold to Miners: https://bit.ly/3HziYrP https://bit.ly/3y5OLgA https://bit.ly/3HzYpeA 04:40 - US Common Charging Standard?: https://engt.co/3y2cD4O https://bit.ly/3Od6mcs 05:38 - Artemis 1 Wet Rocket: https://engt.co/3y0F0R0 06:14 - Cryptostonks: http://bit.ly/2GkIP8y https://bit.ly/339VGVS https://bit.ly/3uUj19Q https://yhoo.it/3bFclob https://yhoo.it/bSRrxsM 07:06 - UFD Deals: https://www.ufd.deals/ https://geni.us/OAQ0AG 07:31 - FFVII Event: https://engt.co/3xHZMTU https://bit.ly/39CP21a https://bit.ly/3zOOT5B https://bit.ly/3y3lymw 09:51 - Ryzen 7000 Sept 15: https://bit.ly/3y5qyHB https://bit.ly/39zKg4A https://bit.ly/3xHyhtK 10:34 - MSI's Mid OC Board: https://bit.ly/3HyVz9T 11:41 - AMD Fixes More: https://bit.ly/3tDOyyM ► Follow me on Twitch - http://www.twitch.tv/ufdisciple ► Join Our Discord: https://discord.gg/GduJmEM ► Support Us on Floatplane: https://www.floatplane.com/channel/uf... ► Support Us on Patreon: https://www.patreon.com/UFDTech ► For the outro music by Kalyptra: https://goo.gl/KyLzTB ► Twitter - http://www.twitter.com/ufdisciple ► Facebook - http://www.facebook.com/ufdtech ► Instagram - http://www.instagram.com/ufd_tech ► Reddit - https://www.reddit.com/r/UFDTech/ Presenter: Brett Sticklemonster Videographer: Brett Sticklemonster Editor: Catlin Stevenson Thumbnail Designer: Reece Hill --- Support this podcast: https://anchor.fm/ufdhotnews/support

Data Coffee
53 (S2E11). WWDC22, Natasha, Bergamot & AI has come to life

Data Coffee

Play Episode Listen Later Jun 18, 2022 67:46


Ведущие подкаста "Data Coffee" обсуждают новости и делятся своими мыслями! Shownotes: 7:45 Новости эпол 32:58 Xsolla закрывает российский филиал: 35:27 Doom запустили прямо в bios 39:34 Спустя годы это всё-таки произошло. теперь нако... 42:11 Minor news for streamlit fans, introducing mult... 46:09 Mozilla запустили “проект бергамот” в бета-тест... 51:12 Google отстранила от работы инженера, который н... 1:02:21 Проект natasha — набор python-библиотек для обр... 1:04:35 Msi анонсировала ножную педаль liberator для иг... Обложка - Dan Gerhards, CC0, via Wikimedia Commons Сайт: https://datacoffee.link, канал в Telegram: https://t.me/datacoffee, профиль в Twitter: https://twitter.com/_DataCoffee_ Чат подкаста, где можно предложить темы для будущих выпусков, а также обсудить эпизоды: https://t.me/datacoffee_chat

Gamekings
EvdWL over Final Fantasy VII, Capcom, Bethesda & Assassin's Creed

Gamekings

Play Episode Listen Later Jun 17, 2022 83:12


Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site. Dé afsluiter van de week staat gewoon lekker voor klaar en kan zo naar je beeldscherm. We zitten ook deze week nog een beetje in de ‘E3' sfeer en zagen opnieuw een flink aantal aankondigingen, nieuwe games en trailers voorbijkomen. En die gaan Huey, Jelle en Koos even lekker samen met jullie doornemen. Waar werden ze blij van, wat viel tegen en wat was interessant? Wat leverde de Final Fantasy VII 25th anniversary stream op? Hoe vonden ze de Capcom Showcase? Hoe kijken ze aan tegen de feestelijkheden rond Assassin's Creed? Wat weten we meer over de games van Bethesda? De drie heren zijn aangeschoven achter de desk en zitten klaar om de afgelopen week met je door te nemen. Al het belangrijke nieuws zie en hoor je voorbij komen in de EvdWL van vrijdag 17 juni 2022. Aziatische week met Final Fantasy VII en Capcom presentaties Het was deze week qua 'E3' even de Aziatische maand. Zowel Capcom als Square produceerden een stream en toonden hun games voor het aankomend jaar. Zat er wat tussen voor de heren en hoe vonden zij dat deze twee Japanse grootmachten het deden? Ubisoft liet een teken van leven zien met hun feest rond Assassin's Creed. Zagen de drie daar nog interessante zaken voorbij komen? Ook wordt er gepraat over de nieuwe game van Kojima, de vermeende PS5 Pro controller en de remake van The Last of Us. Ga er dus maar even lekker voor zitten, koud drankje erbij en begin het weekend op frisse wijze met deze nieuwe editie van Einde van de Week Live. Nieuwe notebooks MSI in de spotlights MSI zet dit keer hun vers aangekondigde Notebooks in de spotlights. Denk aan de Titan GT77 met desktop prestaties en de Raider GE67 met OLED scherm. Wil je meer informatie over deze laptops, check dan even deze link. https://bit.ly/HX-NB

TD Ameritrade Network
MSI, SPOT: Dramatically Underpriced & Room To Grow

TD Ameritrade Network

Play Episode Listen Later Jun 14, 2022 5:53


Chinese competitors of Motorola Solutions (MSI) have been forced out, says Bryan Engler. He talks about his stock pick, MSI and Spotify (SPOT). He discusses how over the medium-term, the street is dramatically underpricing how fat MSI's earnings can grow. He then goes over how SPOT's advertising technology and podcasting abilities are still emerging. Tune in to find out more.

On the Hunt - A League of Legends Podcast
On the Hunt Ep. 56: A Fair MSI - Patch 12.9, 12.10, MSI, and Summer Roster Moves

On the Hunt - A League of Legends Podcast

Play Episode Listen Later Jun 14, 2022 53:09


In this episode of On the Hunt - A League of Legends Podcast, Chris and Raymund are back at it again from a small hiatus to catch up on the LCS happenings from the past month. We briefly recap some key events that took place at MSI before jumping into the highlights of both Patch 12.9 and 12.10, the legendary durability patch. Lastly, we round out the episode by going over roster changes taking place before the Summer Split. This episode was recorded on Wednesday, June 8, 2022. Follow us on Twitter: @OnTheHuntLoL #OnTheHunt #LCS #LeagueOfLegends

Gamekings
EvdWL over Summer Game Fest, Devolver & The Last of Us Remake

Gamekings

Play Episode Listen Later Jun 10, 2022 72:48


Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site. Dé allerbeste afsluiter van de week staat zoals elke vrijdag de afgelopen jaren nu op je beeldscherm.en deze keer is hij extra de allerbeste, want het gaat om de ‘E3' of zoals we het nu bij ons noemen: de NeE3. Afgelopen donderdag was namelijk de Summer Game Fest en we verklappen niet te veel als we zeggen dat daar nogal wat over te vertellen valt. Over games als The Callisto Protocol en Modern Warfare 2, maar ook over het ontbreken van veel top titels en de ophef over The Last of Us Remake. Daan, Jelle & Koos zijn aangeschoven achter de desk en zitten klaar om de de show van donderdag tot op het bot te ontleden, inclusief de vele getoonde trailers. Je ziet en hoort het allemaal in de EvdWL van vrijdag 10 juni 2022. Waarom was het stuk van The Last of Us Remake zo lang? Waar we in deze editie van EvdWL de presentaties van donderdag doornemen, staat er zondag natuurlijk nog een dikke showcase op jullie te wachten. En wel die van Xbox & Bethesda, gevolgd door de PC Gaming Show. We coveren beide shows en beginnen onze stream om 18:00 op Twitch.tv/Gamekings. Kom dus vooral hangen voor een gezellige en gezamenlijke nerdy zondagavond. Mocht je de show live willen bijwonen, dan kan dat in Blast Galaxy samen met een aantal presentatoren. Wil je daar vanaf 17:00 bij zijn, mail naar redactie@gameking.tv. Premium Bazen kunnen gratis naar binnen. Een hoop laptops in de aanbieding tijdens zomer vakantie deals De sponsor van EvdWL, MSI bied je ook deze week een hoop fijne vakantie deals. Met korting op maar liefst acht verschillende laptops zoals de Raider GE76 en de Vector GP76. Genoeg keuze voor entertainment op de weg, in de tent, bungalow of camper. Van deze laptops kan je hier de aanbieding vinden. https://bit.ly/3PyzAn6

ASCP Esty Talk
Ep 123 – The Rogue Pharmacist: Acne: Myths, Medicine, and Methods

ASCP Esty Talk

Play Episode Listen Later Jun 10, 2022 23:44


It's easy to fall for misinformation these days and while estheticians are well versed in acne, it's your clients who may be falling for commons myths and home treatment methods. In this episode of the Rogue Pharmacist with Ben Fuchs, we discuss acne myths, medicine, and methods for treatment, and the real reason your clients have acne.  Associated Skin Care Professionals (ASCP) presents The Rogue Pharmacist with Benjamin Knight Fuchs, R.Ph. This podcast takes an enlightening approach to supporting licensed estheticians in their pursuit to achieve results-driven skin care treatments for their clients. You can always count on us to share professional skin care education, innovative techniques, and the latest in skin science. Benjamin Knight Fuchs is a registered pharmacist, nutritionist, and skin care chemist with 35 years of experience developing pharmacy-potent skin health products for estheticians, dermatologists, and plastic surgeons. Ben's expert advice gives licensed estheticians the education and skin science to better support the skin care services performed in the treatment room while sharing insights to enhance clients' at-home skin care routines. Connect with Ben Fuchs:    Website: www.brightsideben.com    Phone: 844-236-6010    Facebook: www.facebook.com/The-Bright-Side-with-Pharmacist-Ben-Fuchs-101162801334696/    About Our Sponsor:   LAMPROBE The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE  

Spill&Chill
RNG wins MSI Ep.32

Spill&Chill

Play Episode Listen Later Jun 9, 2022 130:24


Vi hyller MSI vinnerene. innblikk i utviklingen av ARMA serien. Vi har sett Stranger Things (og gitt denne sessongen et nytt navn) Obi-Wan er endelig ute, og vi er happy. Og vi introduserer ett etterlengtet segment.

Mormon Sex Info
MSI 148 - Pleasure Prescription: A Surprising Approach to Healing Sexual Pain with Dee Hartmann

Mormon Sex Info

Play Episode Listen Later Jun 7, 2022 52:49


MSI 148 Pleasure Prescription: A Surprising Approach to Healing Sexual Pain with Dee Hartmann   Natasha interviews pelvic floor therapist Dee Hartmann, author of “The Pleasure Prescription: A Surprising Approach to Healing Sexual Pain,” in regards to the role pleasure plays in helping with genital pain and sexual function for female bodies.   Resources discussed:   vulvalove.com   pleasuremovement.com   https://lioness.io   https://www.amazon.com/Pleasure-Prescription-Surprising-Approach-Healing/dp/1643885790/ref=tmm_pap_swatch_0?_encoding=UTF8&qid=&sr=   To help keep Mormon Sex Info going past 2022, please donate at mormonsex.info.

Radio Stone Update
Industry Optimistic for Rest of 2022; Equity Firm Acquires TENAX Majority Stake; more.

Radio Stone Update

Play Episode Listen Later Jun 6, 2022 14:52


A National Kitchen and Bath Association study shows industry optimism for the remainder of 2022; majority stake in TENAX S.p.A. acquired by European equity firm; Mosaic Companies expand U.S. East Coast operations; more. 00:00  Welcome to Radio Stone Update00:34  Industry Survey Shows Positive '22 Outlook03:18  Equity Firm Gets TENAX Stake05:11  A Word from Quantra06:27  Mosaic Companies Expand Operations07:46  Mitigation Needed at Colorado Marble Quarry09:20  Cosentino Reopens Manhattan City Center10:58  MSI Honored for Sustainable Growth11:58  ISFA 2022 Annual Conference in October12:42  November Set for Total Solutions Plus 202213:32  Arizona Tile Expands in Oregon

Gamekings
EvdWL over begin ‘E3' & kwaliteit PlayStation State of Play

Gamekings

Play Episode Listen Later Jun 3, 2022 79:50


Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site. Dé allerbeste afsluiter van de week staat zoals elke vrijdag de afgelopen jaren nu op je beeldscherm. We hebben het natuurlijk over niks anders dan EvdWL. Huey, Jelle & Koos zijn aangeschoven achter de desk en zitten klaar om de afgelopen week samen met jullie door te nemen. We gaan het vandaag hebben vooral hebben over de PlayStation State of Play van donderdagnacht. Want dat was me er een. Wat vonden de drie heren van de trailers die werden getoond? Was dit een mooi begin van de 'E3' periode? Kon het qua game content wedijveren met een ouderwetse E3 presentatie? We gaan in deze EvdWL alle getoonde trailers doornemen en geven natuurlijk passend commentaar. EDn de chat laat zich natuurlijk ook horen. PlayStation State of Play hakte er goed in Maar er was deze week meer nieuws. Zoals berichten over een mogelijke Xbox series X PRO en PS5 PRO in 2023,. Over de eerste beelden van Sonic Frontiers en over Obsidian dat misschien twee games gaat laten zien bij de Xbox & Bethesda Game Showcase. Een showcase die je samen met ons op 12 juni bekijken in Blast Galaxy kan bekijken! we hebben nog wat plek dus als je wilt komen (deuren open 17:00 uur), mail dan snel naar redactie@gamekings.tv. Dit en nog veel meer hoor je in de nieuwe editie van EvdWL. Een hoop laptops in de aanbieding tijdens zomer vakantie deals De sponsor van EvdWL, MSI bied je ook deze week een hoop fijne vakantie deals. Met korting op maar liefst acht verschillende laptops zoals de Raider GE76 en de Vector GP76. Genoeg keuze voor entertainment op de weg, in de tent, bungalow of camper. Van deze laptops kan je hier de aanbieding vinden https://bit.ly/3PyzAn6

The Chrome Cast
Robby loves the Pixel 6 Pro and MSI joins the Chromebox "game"

The Chrome Cast

Play Episode Listen Later Jun 3, 2022 76:47


This week on The Chrome Cast, we dive into why Robby has come full circle and fallen in love with the Pixel 6 Pro. Despite the many high-end options on the market, the Pixel line has an intangible appeal and the 6 Pro is simply the best overall phone that Google has ever made. From there, we dive into some interesting new hardware from the ChromeOS front. ARM appears to be making a move to break free from the budget-minded segment of Chromebooks and soon, we may see ARM-powered Chromebases that rival the current devices like the HP Chromebase 22 All-In-One. Last but not least, it looks like a PC gaming giant may have just joined the ChromeOS playground. Little details are available but MSI appears to be working on a 12th Gen Intel Chromebox and that's exciting news for ChromeOS power users and gamers alike. LINKS I was wrong: the Pixel 6 Pro is by far the superior Pixel experience [VIDEO] New ARM-powered Chromebases are in the works with the MediaTek Kompanio 1380 inside It looks like MSI may be joining the ChromeOS fray, starting with a Chromebox Two more 12th-gen Intel Alder Lake Chromeboxes are in development An additional high-end Pixel may be coming to join the Pixel 7 and Pixel 7 Pro Join our Patreon community and get access to things like behind-the-scenes footage, early access to videos, private Discord server access, an ad-free experience on the mobile and desktop versions of the website, and more. CLICK HERE to be a part of our community. This episode is brought to you by Fresh Roasted Coffee. To check it out, go to https://chromeunboxed.com/coffee/ and use the discount code CHROMEUNBOXED for 15% off your initial purchase! This episode is also brought to you by NordVPN. CLICK HERE to try it out and get 2 years for $3.29 per month. --- Support this podcast: https://anchor.fm/chromeunboxed/support

Bodied: A Cloud9 Fancast
Episode 235: The Boys Are Back

Bodied: A Cloud9 Fancast

Play Episode Listen Later Jun 2, 2022 34:07


Welcome to Bodied. This week hosts Havokpus and Frozencreek are back to talk Cloud9. First, we have WoW Arena, Mang0 talk, the London Spitfire, and VALORANT changes. Next, we have the return of Cloud9 CS:GO and their escapades in Belgium and now in Texas. Last, we have some MSI and Academy talk. Intro: 00:00 World of Warcraft Arena: 01:02 Super Smash Bros. Melee: 01:11 Overwatch: 03:00 VALORANT: 08:53 CS:GO: 15:40 League of Legends: 21:13

Hotline League
Who's BURNED OUT after MSI? Is it a POINTLESS EVENT? Did T1 drop the ball? feat. Raz | HLL 224

Hotline League

Play Episode Listen Later May 31, 2022 134:06


00:00:00 Intro - Disappointment in this MSI event, wonky sleep schedules and more 00:26:33 Aiainz's take: none of the teams that made top 4 at MSI will win Summer Split due to post-MSI slump and different patch 00:40:58 Alienware break! 00:42:36 Softie's take: TSM will be bad until Regi leaves. 00:59:20 Dr.Doktor's take: the last 2 MSIs have been pointless 01:20:00 Camden's take: T1 coaching staff massively underperformed 01:30:58 Grubhub break! 01:32:47 Arsh is worried about Caps burning out 01:42:45 Is Travis too NEGATIVE? 01:50:02 Aetiss's take: viewership is dropping because casters and content creators don't know how to tell good storylines 02:13:10 Outro

Gamekings
EvdWL over het vele nieuws rond PlayStation, 'E3' & The Witcher 4

Gamekings

Play Episode Listen Later May 27, 2022 72:06


Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site. We luiden het weekend zoals elke week in met een verse editie van EvdWL. Dé talkshow als het gaat om het wekelijkse gamenieuws. En ook deze week stroomde het nieuws de redactie op. Vandaag hebben Daan, Jelle en Koos achter de desk plaats genomen en zij gaan vooral veel PlayStation nieuws behandelen. Zij presenteerden de afgelopen week namelijk de jaarrapportage over 2021 en vertelden wat ze in de komende jaren van plan zijn te gaan doen. En daar zaten een aantal spannende vergezichten bij die we je niet willen onthouden. Je gaat het allemaal zien en horen in de EvdWL van vrijdag 25 mei 2022. PlayStation doet een aantal interessante uitspraken Maar er was natuurlijk meer nieuws. De gamesindustrie is meer dan alleen PlayStation. Zo is The Witcher 4 in pre productie gegaan, is de maker van de Xbox bang voor de gevolgen van de Game Pass, hebben we (mogelijke0 releasedata voor Stray, The Lord of the Rings: Gollum en Call of Duty: Modern Warfare 2. Ook is er opnieuw een grote naam vertrokken bij de studio achter Halo Infinite en meldde een Chinese TV producent dat we in 2023 een PS5 Pro en Xbox Series X Pro mogen gaan verwachten. Kortom, meer dan genoeg nieuws om je de komende anderhalf uur aan de buis of headset gekluisterd te houden. Krijg fijne kortingen bij de Vakantie Deals van MSI De zomervakantie nadert. Het vakantiegeld is uitgekeerd. En als dat niet zo is, dan zou ik je baas even bellen. Anyway, deze tijd van het jaar is een vast moment voor MSI om met hun Vakantie Deals te komen. Laptops voor mooie prijzen. Je kunt alle deals hier op je gemak checken https://bit.ly/3PyzAn6

ASCP Esty Talk
Ep 120 - The Rogue Pharmacist: Peptides - Fad or Function?

ASCP Esty Talk

Play Episode Listen Later May 27, 2022 25:10


Not to be confused with proteins, peptides are amino acids that serve to slow the aging process and are a major buzzword in esthetics. In this episode of the Rogue Pharmacist with Ben Fuchs, we discuss what peptides really are and if they're worth the hype.   Associated Skin Care Professionals (ASCP) presents The Rogue Pharmacist with Benjamin Knight Fuchs, R.Ph. This podcast takes an enlightening approach to supporting licensed estheticians in their pursuit to achieve results-driven skin care treatments for their clients. You can always count on us to share professional skin care education, innovative techniques, and the latest in skin science. Benjamin Knight Fuchs is a registered pharmacist, nutritionist, and skin care chemist with 35 years of experience developing pharmacy-potent skin health products for estheticians, dermatologists, and plastic surgeons. Ben's expert advice gives licensed estheticians the education and skin science to better support the skin care services performed in the treatment room while sharing insights to enhance clients' at-home skin care routines.   Connect with Ben Fuchs:    Website: www.brightsideben.com    Phone: 844-236-6010    Facebook: www.facebook.com/The-Bright-Side-with-Pharmacist-Ben-Fuchs-101162801334696/    About Our Sponsor:   LAMPROBE The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE  

The Dive - A League of Legends Esports Podcast
Who Will Win MSI? | Divephoria MSI 2022 Episode 3

The Dive - A League of Legends Esports Podcast

Play Episode Listen Later May 26, 2022 72:43


In the final episode of Divephoria for MSI 2022, Drakos, Kobe and Azael recap the Rumble stage, and make their predictions for the upcoming knockout bracket. Divephoria is available on Apple Podcasts, SoundCloud, Spotify, YouTube, Anchor and more. Watch the 2022 Mid-Season Invitational at http://lolesports.com Follow LoL Esports for more updates on MSI 2022: Twitter - http://twitter.com/lolesports Facebook - http://facebook.com/lolesports Instagram - http://instagram.com/lolesports #LCS #TheDive #TheDivePodcast #LEC #EUphoriaPodcast --- Send in a voice message: https://anchor.fm/the-dive-esports-podcast/message

Euphoria Podcast
Who Will Win MSI? | Divephoria MSI 2022 Episode 3

Euphoria Podcast

Play Episode Listen Later May 26, 2022 72:50


In the final episode of Divephoria for MSI 2022, Drakos, Kobe and Azael recap the Rumble stage, and make their predictions for the upcoming knockout bracket. Divephoria is available on Apple Podcasts, SoundCloud, Spotify, YouTube, Anchor and more. Skip around to your favorite parts: 0:00 Intro 2:25 Recap Rumble Stage 3:35 SGB 11:57 PSG 14:47 RNG 16:59 Future of VCS, PCS 18:03 RNG vs.EG 19:24 RNG in Rumble Stage 23:25 How can EG win 29:33 Last EG vs. G2 game 35:43 Ashley Kang interview with Impact 43:42 Confidence and motivation 48:38 T1 vs. G2 50:43 Broken Blade 53:21 G2 weaknesses 58:48 How to beat T1 1:01:58 Series prediction 1:10:15 Outro Watch the 2022 Mid-Season Invitational at http://lolesports.com Follow LoL Esports for more updates on MSI 2022: Twitter - http://twitter.com/lolesports Facebook - http://facebook.com/lolesports Instagram - http://instagram.com/lolesports #LCS #TheDive #TheDivePodcast #LEC #EUphoriaPodcast

Hotline League
MSI's Rumble Stage comeback! The West stays afloat; "Busan Library" EXPLAINED?? | HLL 223

Hotline League

Play Episode Listen Later May 25, 2022 120:33


00:00:00 Intro - MSI MADNESS! And movie reviews! 00:29:00 Kevin's take: EG has a higher chance to upset than G2 does 00:42:00 Alienware break! 00:43:24 Joshua's take: G2's run is proof that the international gap is mostly mental 00:59:17 Zemelcai's take: despite a mediocre group stage, rumble redeemed MSI 01:16:08 Kayokio's take: The bias around caster/narrative makes it hard to enjoy the broadcast 01:33:20 Weekly Grubhub code!! 01:34:58 Rob shows us what the Busan venue looks like for fans 01:55:40 Outro

Leaguecast: a League of Legends Podcast

The boys talk more about the Bel'Veth ability reveal, Patch 12.10, MSI, a new roundtable question, lots of emails and more on episode 536 of Leaguecast! Get 20% OFF @manscaped + Free Shipping with promo code LEAGUECAST at MANSCAPED.com! #ad #manscapedpod Grab your EXCLUSIVE NordVPN Deal by going to https://nordvpn.com/leaguecast to get up a Huge Discount off your NordVPN Plan + Free Threat Protection + 1 additional month for free! It's completely risk free with Nord's 30 day money-back guarantee! Email us - mail@leaguecastpodcast.com  Support us - https://www.patreon.com/leaguecast  Tweet us - https://twitter.com/leaguecast   Facebook - https://www.facebook.com/Leaguecast/   Join Our Discord - https://discord.gg/leaguecast  Visit our Website - https://leaguecastpodcast.com/  To skip our week discussion go to 9:55

Money Talks
Money Talks: Getting a Job with MDES

Money Talks

Play Episode Listen Later May 24, 2022 49:03


Who needs a job? Who needs a better job? Who has no idea what they want to do so they need help figuring out what kind of job would suit them? If you answered yes to any of these – have we got a broadcast for you. Our guests are Daphne James from WIN Job Centers and Adam Todd from the Governor's Job Fair Network.https://mdes.ms.gov/WIN Job Centers https://mdes.ms.gov/win-job-centers/Governor's Job Fairs https://www.jobfairs.ms.gov/Don't forget to register to attend! https://wings.mdes.ms.gov/wings/spring/self-service/job-fair/job-fair-registration;jsessionid=429BB51DD0F68C55BA00AAA1AA69A2B2?execution=e1s1Greenwood Leflore Job Fair: Begins: 9:00 am, May 25, 2022Ends: 1:00 pm, May 25, 2022Leflore County Civic Center200 Mississippi Hwy 7Greenwood, MSEast Mississippi Job FairBegins: 9:00 am, June 7, 2022Ends: 1:00 pm, June 7, 2022The Communiversity 2.07003 S Frontage RoadColumbus, MSI-59 Job FairBegins: 9:00 am, June 16, 2022Ends: 1:00 pm, June 16, 2022Sawmill Square Mall - inside the old JCPenney910 Sawmill RoadLaurel, MSMississippi Re-Entry Job Fair 2022When: 06/22/2022 : 9:00 AM - 1:00 PMWhere: MS Agriculture & Forestry Museum - Sparkman Building, 1150 Lakeland, DriveJackson, MississippiSmart Start https://skillupmississippi.com/smart-start/Fidelity Bonding Program https://mdes.ms.gov/i-need-a-job/job-searching-resources/fidelity-bonding-program/ See acast.com/privacy for privacy and opt-out information.

Podcast de Reset
¡Centinela de la semana! ya no somos la peor región del mundo

Podcast de Reset

Play Episode Listen Later May 24, 2022 61:08


Llegó el Centinela de la Semana con la previa al MSI 2022 en su Rumble Stage, además, Rainbow Six y CS:GO están por llegar a su clímax. ¡Únete a la conversación! Síguenos en nuestras redes sociales: Facebook: http://www.facebook.com/Reset.tvTwitter: @ResetMXTwitch: https://www.twitch.tv/resetmxoficialSitio web: http://resetmx.com/ The post ¡Centinela de la semana! ya no somos la peor región del mundo appeared first on ResetMX.

Gamekings
EvdWL over Xbox, PlayStation, Starfield & Final Fantasy VII Remake

Gamekings

Play Episode Listen Later May 20, 2022 89:37


Deze talkshow wordt mede mogelijk gemaakt door MSI. Alle meningen in deze video zijn onze eigen. MSI heeft inhoudelijk geen inspraak op de content en zien de video net als jullie hier voor het eerst op de site. Het is alweer bijna weekend en weten nu wel wat dat betekent: een nieuwe Einde van de Week Live staat voor je klaar. Met vandaag het trio Huey, Jelle én Skate op je beeldscherm. EvdWL is dé podcast om je week mee af te sluiten. Zo blijf je makkelijk up-to-date met de laatste nieuwtjes uit de games-industrie. Met vandaag onderwerpen over onder andere Mafia 4, Starfield, een nieuwe game waar de studio van Dying Light 2 aan werkt, de perikelen van PlayStation en Xbox en nog veel meer. Alles ga je zien en horen in de Einde van de Week Live van vrijdag 19 mei 2022. PlayStation Showcase zou wel eens in juni kunnen plaatsvinden In deze editie hebben de drie het over de mogelijk komst van de PlayStation Showcase in juni. En, als we de Xbox community mogen geloven, hebben we een paar dagen geleden de eerste informatie gekregen over Mafia 4. Mafia 4 zou zich vóór de allereerste Mafia game afspelen aan het begin van de jaren 1900. Natuurlijk moet het dan ook in 'the Home of the Mafia' afspelen, namelijk Sicily, Italië. Hier volg je het leven van de familie van Don Salieri, ook wel bekend als de baas van Tommy in Mafia 1. Wanneer deze game uit gaat komen is nog niet duidelijk. Hoeveel zin zouden de hebben presentatoren in deze game? Nieuwe laptop deals op de website van MSI Wegens het grote succes continueert MSI de aanbieding van vorige week dat betekent dus dat je ook deze week bij Alternate maar liefst 600 euro korting kunt krijgen op de MSI GP76 Vector (12UH-426NL). Het betreft een gaming laptop met een 12e generatie i9 processor en RTX3080 Videokaart aan boord! Je kan de aanbieding via https://bit.ly/3kOMdMp vinden.

What's Next|科技早知道
S6E13|MSI 巨大争议的背后,价值千亿的电竞市场已把 Web3 抱入怀中

What's Next|科技早知道

Play Episode Listen Later May 20, 2022 41:02


一场被讨伐的国际电竞赛事,为什么看到 Web3 化的电竞未来?5 月 13 日,「RNG 重赛」作为关键词在新浪微博的话题讨论解锁了 6 亿次阅读的成就,此后海内外社媒平台和论坛不断出现关于 2022 MSI 和 拳头游戏的话题讨论,英雄联盟、DOTA、反恐精英等游戏的电竞项目正在加速破圈。 Newzoo 预测,未来全球会有 2.6 亿人至少每月看一次电竞,这个价值千亿美元的市场将以两位数的年复合速度不断成长。在去年 11 月 宣布英雄联盟等八款游戏正式入选杭州亚运会之后,不仅仅是传统体育提高对电竞的关注度,互联网公司与硬件厂商也持续加大对电竞行业的投入,讨论元宇宙、 Web3 与这个行业如何有机结合。作为有经营大型国际电竞赛事有十余年的拳头游戏,在这一届的 MSI 上摔的跟头,给从业者与观察者带来哪些重要的技术与行业思考? 本期节目,代班主播刘灿与「懒熊体育」主编郑浩榕、前经纬创投 VP 庄明浩的对谈,重新梳理这场争议的来龙去脉以及背后的电竞产业格局。 MSI 在技术上到底出了什么样 bug?赛事主办方在处理这个问题上为什么遭受了公平性的质疑?电竞行业也在向传统体育看齐吗?疫情红利为什么不会长期利好电竞行业?电竞俱乐部为什么也发 NFT?Web3 产品在如何借鉴游戏玩法? 这是「What's Next|科技早知道」第一次覆盖与电竞相关的话题,如果有对这类话题感兴趣的小伙伴,或者是电竞行业的从业者、投资人,对于电竞和 Web3 非常了解,欢迎在评论区与社交媒体平台上与我们一起交流! 特别分享 重磅!「声动活泼」的新节目 声音特稿「跳进兔子洞」将在 5 月 31 日 与大家见面啦! 节目制作人佳勋此前曾报道过美国大选,也调查过十几年未破凶杀案,听过「声东击西」的小伙伴应该还记得2021年的声音时光胶囊吧「#196 请收下这枚记录 2021 年的声音时光胶囊 (https://etw.fm/196)」,这就是经过佳勋之手的节目。 福利!订阅声动小邮筒(newsletter)的用户都可以在 5 月 31 日上线之前抢先收听「跳进兔子洞」,请小胡同的伙伴们认真查阅最近的邮箱邮件,我们会在邮件里告诉大家如何领取福利。 欢迎关注「声动活泼」微信公众号,或者添加微信「声小音」,咨询新节目的相关事宜。 5 月 31 日,和我们一起「跳进兔子洞」吧! 本期人物 刘灿,「科技早知道」监制 郑浩榕,「懒熊体育」主编 庄明浩,前经纬创投 VP,前熊猫直播 VP 主要话题 [03:40] RNG 为什么会重赛?为什么网络延迟不一致会导致重赛? [10:20] 不只是一场公关危机?但英雄联盟不会退出亚运会? [16:18] 有 bug 的延迟网络工具在 2020 年就已经用了?发行商和俱乐部就是行业的一二环? [22:03] 电竞的生意逻辑跟足球俱乐部很像?俱乐部怎么扭转弱势的谈判地位? [29:09] 长期看,疫情并不是利好电竞?俱乐部也发 NFT ? [37:30] 游戏中的人性在公司治理中被借鉴?升职涨薪也要积累经验值? 延伸阅读 - 「拳头」针对此次导致重赛的技术问题说明:拳头游戏技术博客: 远程比赛时的人工延迟使用 (https://weibo.com/ttarticle/p/show?id=2309404770219460790187) - 「Fortune」关于全球电竞俱乐部的排名:The Most Valuable Esports Companies 2022 (https://www.forbes.com/sites/brettknight/2022/05/06/the-most-valuable-esports-companies-2022/?sh=434ed291599f) - 「Newzoo」关于 2022 全球电竞市场的报告:Newzoo's Global Esports & Live Streaming Market Report 2022 | Free Version (https://newzoo.com/insights/trend-reports/newzoo-global-esports-live-streaming-market-report-2022-free-version/) - 「TechCrunch」关于 Fantasy Sports 的报道:Fantasy sports platforms could have a big future in blockchain (https://techcrunch.com/2018/04/11/fantasy-sports-platforms-could-have-a-big-future-in-blockchain/) - 「鹰眼时间」在今年 5 月分析 LPL 的播客:Vol.19 电竞产业就像八九点钟的太阳,看着很好 (https://www.xiaoyuzhoufm.com/episode/626e656e3e8abf901a68d877) - 「泡腾VC」在 2021 年 3 月 分析字节跳动游戏布局 的播客::S2E06 小声冒泡 | 战投疯狂撒币,对字节来说 40 亿美金的沐瞳贵了吗? (https://popvc.fireside.fm/s2e06) 使用音乐 Misguided Path-Bonnie Grace 幕后制作 监制:刘灿 后期:Luke 运营:Yao 封面设计:饭团 关于节目 原「硅谷早知道」,全新改版后为「What's Next|科技早知道」。放眼全球,聚焦科技发展,关注商业格局变化。 关于我们 声动活泼的宗旨是「用声音碰撞世界」,致力于为人们提供源源不断的思考养料。 - 我们还有这些播客:声东击西 (https://etw.fm/episodes)、声动早咖啡 (https://sheng-espresso.fireside.fm/)、反潮流俱乐部 (https://fanchaoliuclub.fireside.fm/)、泡腾 VC (https://popvc.fireside.fm/)、商业WHY酱 (https://msbussinesswhy.fireside.fm/) - 欢迎在即刻 (https://okjk.co/Qd43ia)、微博等社交媒体上与我们互动,搜索 声动活泼 即可找到我们 - 期待你给我们写邮件,邮箱地址是:ting@sheng.fm - 如果你喜欢我们的节目,欢迎 打赏 (https://afdian.net/@shengfm)支持或把我们的节目推荐给一两位朋友 欢迎加入声动胡同小社区! 也许你知道「声动活泼」办公室在北京二环内的胡同里,事实上我们也有一个线上的「声动胡同小社区」。成为社区会员,你可以收到一周不少于三次的来自「声动小邮筒」的邮件,同时还可以参加我们各种各样的线上和线下活动,或者是一些有趣的游戏。 点击这里 (https://shengpodcasts.notion.site/a977c74222484894a9fe6245bc0f4dba)即可了解社区氛围。我们期待你加入这个虚拟胡同社区来支持我们,并和我们一起亲近交流,和有趣的人进行「碰撞」,收获新知、友谊并看见更大的世界。 国内用户(年付):加入声动胡同小社区 (https://sourl.cn/G4B2Wt) 海外用户(月付):加入声动胡同小社区 (https://sdhp.memberful.com/join) 期待你的加入! Special Guests: 庄明浩 and 郑浩榕.

Podcast de Reset
Centinela de la semana! mercado de transferencias edition

Podcast de Reset

Play Episode Listen Later May 19, 2022 58:52


Arrancó el Mercado de Transferencias en League of Legends y tendremos la previa al MSI 2022. Además, te contamos nuestra Guía de Supervivencia para el MSI 2022. ¡Únete a la plática! Síguenos en nuestras redes sociales: Facebook: http://www.facebook.com/Reset.tvTwitter: @ResetMXTwitch: https://www.twitch.tv/resetmxoficialSitio web: http://resetmx.com/ The post Centinela de la semana! mercado de transferencias edition appeared first on ResetMX.

The Dive - A League of Legends Esports Podcast
Rumble Stage Preview | Divephoria MSI 2022 Episode 2

The Dive - A League of Legends Esports Podcast

Play Episode Listen Later May 19, 2022 66:22


Drakos is joined by Azael and Kobe to recap the MSI 2022 group stage, discuss their current MVP, tournament meta, and who are their favorites moving into the rumble stage. Divephoria is available on Apple Podcasts, SoundCloud, Spotify, YouTube, Anchor and more. --- Send in a voice message: https://anchor.fm/the-dive-esports-podcast/message

Euphoria Podcast
Rumble Stage Preview | Divephoria MSI 2022 Episode 2

Euphoria Podcast

Play Episode Listen Later May 19, 2022 66:22


Drakos is joined by Azael and Kobe to recap the MSI 2022 group stage, discuss their current MVP, tournament meta, and who are their favorites moving into the rumble stage. Divephoria is available on Apple Podcasts, SoundCloud, Spotify, YouTube, Anchor and more. Skip around to your favorite parts: 0:00 Intro 1:39 EG mental pre MSI 5:06 Group C recap 8:02 caPs 16:24 Groups MVP 19:05 EG 21:29 Format 23:27 SGB 27:23 Matches to watch 28:19 G2, RNG, T1 33:50 Best jungler so far 37:03 Superman and old League 40:03 MSI Meta 49:06 PSG 53:33 Tournament favorite 56:57 Zeus and naming conventions 1:01:34 Day 1 schedule 1:04:26 Outro with clapping Watch the 2022 Mid-Season Invitational at http://lolesports.com Follow LoL Esports for more updates on MSI 2022: Twitter - http://twitter.com/lolesports Facebook - http://facebook.com/lolesports Instagram - http://instagram.com/lolesports #LCS #TheDive #TheDivePodcast #LEC #EUphoriaPodcast

Hotline League
MSI DRAMA!! Can T1 win UNDEFEATED? Can EG make it out of Rumble Stage? | HLL 222

Hotline League

Play Episode Listen Later May 18, 2022 116:05


00:00:00 Intro - Mark's MSI experience & movie chat 00:12:48 MSI drama-llama-rama 00:26:50 Michael thinks the MSI format is fine as it is 00:42:28 Alienware break! 00:44:13 Lord-Audie's hot take: the current MSI format does a huge disservice to minor regions 01:04:33 Simon's take: inflating everyone else's ping for RNG is catering to Chinese fanbase 01:16:55 Brief B.Sanderson chat & tech issues 01:25:18 Grubhub break! 01:27:29 Jake's take: T1 is making MSI look easy, can win undefeated 01:35:30 Can EG make it out of Rumble Stage? 01:44:05 Yesshua's take: if Blabber/Jensen synergy still exists, C9 can win summer and do well at Worlds 01:53:20 Outro

Leaguecast: a League of Legends Podcast

The boys talk more about the Bel'Veth teaser, Brand + Nami bot, MSI, a new roundtable question, lots of emails and more on episode 535 of Leaguecast! Get 20% OFF @manscaped + Free Shipping with promo code LEAGUECAST at MANSCAPED.com! #ad #manscapedpod Grab your EXCLUSIVE NordVPN Deal by going to https://nordvpn.com/leaguecast to get up a Huge Discount off your NordVPN Plan + Free Threat Protection + 1 additional month for free! It's completely risk free with Nord's 30 day money-back guarantee! Email us - mail@leaguecastpodcast.com  Support us - https://www.patreon.com/leaguecast  Tweet us - https://twitter.com/leaguecast   Facebook - https://www.facebook.com/Leaguecast/   Join Our Discord - https://discord.gg/leaguecast  Visit our Website - https://leaguecastpodcast.com/ 

The Jungle
The Jungle: Is MSI the Worst Esports Format EVER?! | LoL Esports Review

The Jungle

Play Episode Listen Later May 17, 2022 74:47


League Of Legends, from the awful format in recent MSI LoL, MSI 2022 matches affecting RNG LoL's performance, to EG LoL's shock win in EG vs G2, The Jungle's expert hosts provide their opinions and informed stances on the must-know beats from the world's biggest competitive esports title, LoL and its professional leagues LEC, LCS, LPL and the LCK. In this The Jungle League of Legends podcast, Daniel ‘dGon' Gonzales, Christopher ‘MonteCristo' Mykles and Christian ‘IWDominate' Rivera cover the most groundbreaking match-ups and outstanding plays, in recent LoL esports, including the likes Red Canids LoL, Evil Geniuses LoL, G2 LoL, G2 Caps, T1, Gumayusi LoL and RNG, including LoL highlight performances and underperformances, as well as their "GOD or DOG" of the week. 00:00 Ping issues & RNG Rematch Controversy 12:44 MSI: Worst Format EVER?! 24:23 Saigon Buffalo Talk & EG vs G2 Review 48:53 Can RNG Beat T1? 56:32 Will EG Miss Out on Top 4?! 1:02:44 God or Dog: Danny in Worst-EVER Form!

FTW with Imad Khan: An Esports And Competitive Gaming Podcast
Ping Issues Plague MSI 2022 ft. Tyler Esguerra

FTW with Imad Khan: An Esports And Competitive Gaming Podcast

Play Episode Listen Later May 16, 2022 13:44


MSI 2022 is taking place in South Korea. Chinese teams such as Royal Never Give Up, or RNG, are having to play from China due to Covid restrictions. To accommodate competition, Riot has implemented a special network latency tool to keep competition fair. Ping was meant to be set at or near 35 milliseconds. But in-tournament, ping issues have cropped up and things have not gone according to plan. Dot Esports Tyler Esguerra returns to the show to break it all down.

ASCP Esty Talk
Ep 117 - The Rogue Pharmacist: Is Colloidal Oatmeal All It's Cracked Up to Be

ASCP Esty Talk

Play Episode Listen Later May 13, 2022 20:57


We've all heard of oatmeal. Some of us may have even bathed in it as kids when our skin was irritated. But did you know colloidal oatmeal has many skin benefits and is often found in some of the creams we use every day? In this episode of The Rogue Pharmacist with Ben Fuchs, we discuss colloidal oatmeal's benefits, side effects, how to use it, and the skin conditions it may help.   Associated Skin Care Professionals (ASCP) presents The Rogue Pharmacist with Benjamin Knight Fuchs, R.Ph. This podcast takes an enlightening approach to supporting licensed estheticians in their pursuit to achieve results-driven skin care treatments for their clients. You can always count on us to share professional skin care education, innovative techniques, and the latest in skin science.    About Benjamin Knight Fuchs, R.Ph:   Benjamin Knight Fuchs is a registered pharmacist, nutritionist, and skin care chemist with 35 years of experience developing pharmacy-potent skin health products for estheticians, dermatologists, and plastic surgeons. Ben's expert advice gives licensed estheticians the education and skin science to better support the skin care services performed in the treatment room while sharing insights to enhance clients' at-home skin care routines.    Connect with Ben Fuchs:     Website: www.brightsideben.com    Phone: 844-236-6010     Facebook: www.facebook.com/The-Bright-Side-with-Pharmacist-Ben-Fuchs-101162801334696/     About Our Sponsor:   LAMPROBE The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE

Hotline League
Is MSI SCUFFED? Will EG come back to NA stronger than ever? LCS Mockumentary?! | HLL 221

Hotline League

Play Episode Listen Later May 12, 2022 125:24


00:00:00 Intro - Mark's in Germany! 00:14:45 Regi/DL WaPo stuff 00:24:53 ChezBurglur's take: it doesn't matter who wins this MSI, this will be the most scuffed/controversial tournament in league history 00:45:06 Alienware break! 00:48:02 Inscrutiable's take: the way the fans are flaming young NA players is unacceptable 00:58:07 Brakthir's take: if Danny/Jojo continue to do poorly at MSI, the hype around them will do more harm than good 01:13:58 Timmychanga trolls the new LoL Paramount+ TV show 01:28:15 Grubhub code below! 01:31:26 Izzdaer predicts T1/G2 Final because RNG will drop both games 01:40:18 pfwangers thinks Riot should require coaches to do more post-game interviews 01:49:34 Mike's take: EG are ramping up right now, they'll stomp summer LCS 02:00:20 Outro

What's The Matter With Me? Podcast

i had a birthday dinner and didn't wear a mask Shout outs to the ceramicist brian R. Jones who likes the longer episodes- he makes the stuff at brianrjones.comhe hangs out in a ceramics studio. i attended Alfred University for a single semester and I got him and Steve theretry to calm down and go slowerI revisited the last night for dinner journal, it had been 13 months. Last night For dinner we had left over meatloaf and martini's made with cheap gin but at least there was plenty of it5 oz gin to 1.5oz dry vermouth, garnished with banana peppers. it wasn't very goodme & my wife: Ronin commonsense media sounds like the answer is, sounds fine/ nobunch of ex-govt spies fighting over a briefcasewent over it last time: Elon musk is named after a smell, On the other hand John Hoppin is the name of a less wealthy and less popular smell that doesnt own twitterI'm riding the exercise bike 2-3x per weekI got asked by another parent in San Leandro if it had happened to me recently and for a moment i wasnt sure if they meant the wheelchair or MSi told them that i had the wheelchair almost a full year before i would ride it around in publicit was recommended to me by an occupational therapist at the stanford neuroscience a couple years before thatshe told me it would help me get there- not spend my energy to get therei'm tired of falling and hitting my head and having to get staples in my headReading foreign cuisine cookbooks- Ethiopian smoked milk or waterGoing to dinner at a Moroccan restaurant on SaturdayMy wife wanted to support the idea of journeying to EthiopiaRoger Maris visited JFK in the white house in his capacity as MS Society's national campaign co chairman in 1962Last night for dinner and the night before i had pb&j for dinnerwent to my 2nd kfjc meeting since corona, raided the spliff binWet leg, kyle ransonTook the kids to baseball, made dinner, all by myself but i had help. The burger place closedi was afraid i would lose my licenseDmv workedHayward dmv was coolthe guy had a hat that said oldies car club and the bull was scrunched up like anthrax - he told me i should work thereso i'm afraid tommy lee jones is going to pull me out of line so he can show me some of his techniquesignoring disabled people all the way up to euthanizing them are on a spectrum together (like the way microagression and out right aggression) are both kinds of discrimination Need advice about a wheelchair lift for the car, i know there a re listeners who use wheelchairs, i need to get a machine that takes my chair out of the car bc i dont like someone doing it who is either a woman or older than me.its for the opticsHave you heard the sound of the atmosphere dragging across the EarthI went to birthday dinner in San FranciscoI had a 3 hour mriThen i had rods drilled into my jaw

W2M Network
MSI 2022 - Group Stage, Day 2

W2M Network

Play Episode Listen Later May 11, 2022 75:37


Andesian and Dr. Manhattan are back at it again! They'll recap what was an exciting Day 1 (for almost everyone except Dr. M), review their predictions, and get ready for the opening game of Day 2 as G2 takes on Evil Geniuses in Group Stage play. You can view the video version of the live stream on YouTube here: https://youtu.be/N80o2cJ9yro While you're here, join us on Discord! https://discord.gg/aydMgvUN9d

W2M Network
MSI 2022 Special Live Coverage

W2M Network

Play Episode Listen Later May 11, 2022 120:21


Why are we up so late at night? Well, it's not our fault that #MSI2022 is coming to us, and therefore you, live from Busan, South Korea! Well, guess what? We're going to cover the start of the tournament live! Yes, Andesian and Dr. Manhattan will have their own alternate commentary alongside catching up with all the big news from LCS over recent weeks. The Washington Post article about TSM and Reginald is here: https://www.washingtonpost.com/video-games/2022/05/04/tsm-andy-dinh-misclassification/ You can watch the video of the livestream on YouTube here: https://youtu.be/YSBBxSGxNEU While you're here, join us on Discord! https://discord.gg/aydMgvUN9d

Leaguecast: a League of Legends Podcast

The boys talk more about the damage reduction patch, patch 12.9, MSI, a new roundtable question, lots of emails and more on episode 534 of Leaguecast! Get 20% OFF @manscaped + Free Shipping with promo code LEAGUECAST at MANSCAPED.com! #ad #manscapedpod Grab your EXCLUSIVE NordVPN Deal by going to https://nordvpn.com/leaguecast to get up a Huge Discount off your NordVPN Plan + Free Threat Protection + 1 additional month for free! It's completely risk free with Nord's 30 day money-back guarantee! Email us - mail@leaguecastpodcast.com Support us - https://www.patreon.com/leaguecast Tweet us - https://twitter.com/leaguecast  Facebook - https://www.facebook.com/Leaguecast/  Join Our Discord - https://discord.gg/leaguecast Visit our Website - https://leaguecastpodcast.com/ To skip our week discussion go to 26:30

Butter Cuts
Only a Couple More Weeks!

Butter Cuts

Play Episode Listen Later May 10, 2022 59:52


Sergio says adios??? “Couple more weeks” Martin Kaymar is in with LIV DP World Tour; Thorborn Olesen Mother Nature is undefeated! Keegan Bradley collapses Max Home wins a wet and windy Wells Fargo Championship. 4th win for Home and the wins gets him into the Top 30 OWGR. Titleist semi-sweep - In addition to golf balls, Titleist was also the most trusted driver, hybrid, utility iron, iron, wedge and putter at the event Max Homa WITB Driver: Titleist TSi3 (10 degrees, A1 SureFit setting)
Shaft: Fujikura Ventus Black 6 X 3-wood: Titleist TSi2 (15 degrees, A1 SureFit setting)
Shaft: Aldila Rogue Silver 130 MSI 80 TX 5-wood: Titleist TSi2 (21 degrees)
Shaft: Graphite Design Tour AD XC 9 TX Irons: Titleist T100S (4), Titleist T100 (5), Titleist 620MB (6-9)
Shafts: KBS $ Taper 130 X Wedges: Titleist Vokey Design SM9 (46-10F, 50-12F, 56-14F, 60-04L)
Shafts: KBS $ Taper 130 X (46), KBS Hi Rev 2.0 125 S (50-60) Putter: Scotty Cameron Phantom X T5.5 Prototype Ball: Titleist Pro V1 * “Max was looking for a little more height throughout the bag (versus the previous generation Pro V1 he was playing),” said Jeff Beyers, tour consultant for Titleist Golf Ball R&D. “With 2021 Pro V1 he was seeing that increase in peak height and the steeper angle of descent that he wanted. We went through a lot of clubs, he really liked the window, how consistently the ball was flying – and the numbers were right in line. The softer feel was also a big plus for him.” - Grips: Golf Pride Tour Velvet

The Dive - A League of Legends Esports Podcast
Group Stage Preview | Divephoria MSI 2022 Episode 1

The Dive - A League of Legends Esports Podcast

Play Episode Listen Later May 9, 2022 84:10


Divephoria returns for MSI 2022! Drakos is joined by MarkZ and Dagda to discuss tournament favorites, players to watch, and the MSI meta with a special guest from the League of Legends design team. Divephoria is available on Apple Podcasts, SoundCloud, Spotify, YouTube, Anchor and more. Watch the 2022 Mid-Season Invitational at http://lolesports.com Follow LoL Esports for more updates on MSI 2022: Twitter - http://twitter.com/lolesports Facebook - http://facebook.com/lolesports Instagram - http://instagram.com/lolesports #LCS #TheDive #TheDivePodcast #LEC #EUphoriaPodcast --- Send in a voice message: https://anchor.fm/the-dive-esports-podcast/message

Leaguecast: a League of Legends Podcast

Aidan is back and the boys talk about the damage reduction patch, MSI news, LCS, a new roundtable question, lots of emails and more on episode 533 of Leaguecast! Get 20% OFF @manscaped + Free Shipping with promo code LEAGUECAST at MANSCAPED.com! #ad #manscapedpod Grab your EXCLUSIVE NordVPN Deal by going to https://nordvpn.com/leaguecast to get up a Huge Discount off your NordVPN Plan + Free Threat Protection + 1 additional month for free! It's completely risk free with Nord's 30 day money-back guarantee! Email us - mail@leaguecastpodcast.com Support us - https://www.patreon.com/leaguecast Tweet us - https://twitter.com/leaguecast  Facebook - https://www.facebook.com/Leaguecast/  Join Our Discord - https://discord.gg/leaguecast Visit our Website - https://leaguecastpodcast.com/ To skip our week discussion go to 14:20

Hotline League
LCS MVP Summit leaves-- what does it mean? Can TSM come back in summer? feat. Revenge | HLL 220

Hotline League

Play Episode Listen Later May 3, 2022 140:21


00:00:00 Intro - Revenge returns! Roster changes, Summit's departure 00:25:46 Wizard's take: Winsome wasn't LCS ready and Summit was a poor teammate after LS left 00:43:43 Alienware break! 00:45:38 Oscar's take: despite C9 looking better on paper, TSM will be in a better position as an org by the end of summer 00:58:04 PapaDon's take: TSM's effort to finish top 3 instead of rebuilding feels pathetic and bad for LCS 01:16:41 Squizzomatic's take: 100T needs to replace 2 of these 3: Huhi, Closer, Abbedagge 01:33:22 Rob is frustrated about MSI's lack of transparency around ticket sales, schedule, etc. 01:43:13 CadmusAres says Jack should take responsibility and answer questions about C9 roster changes 02:00:15 Nicole says Travis is WRONG about Summit's leaving being bad for the league 02:15:15 Outro

rePROs Fight Back
Papua New Guinea: Providing Reproductive Health Care in a Highly Stigmatized Environment

rePROs Fight Back

Play Episode Listen Later May 3, 2022 42:50


Note: We recorded this episode prior to the leaked document showing the Supreme Courts intent to overturn the right to abortion. While unfortunately we don't talk about it in the episode we will be recording an emergency episode soon to talk about what happened.  Women and girls in the Pacific region face a variety of barriers to accessing sexual and reproductive healthcare. Geographic isolation, lack of bodily autonomy, and some of the world's highest rates of sexual and gender-based violence contribute to high maternal mortality, low contraceptive prevalence and pervasive gender inequality. Myths and misconceptions around sex, reproduction and gender norms are rife, creating stigma and further impacting access to SRHR services. Kelly Durrant, External Relations Director at MSI Asia Pacific, speaks to us about addressing some of these challenges.  Papua New Guinea (PNG) is the largest country in the pacific and the third largest island nation globally, home to approximately 9 million people—85% of which live in rural locations. Even before the pandemic, the country battled high rates of tuberculosis, HIV/AIDS, malaria, maternal and child mortality, and inadequate primary healthcare in rural areas. MSI Asia Pacific has worked in Papua New Guinea since 2006, and is the largest – and in many provinces, the only – SRHR provider in the country. Teams of MSI-trained healthcare workers, community mobilizers and educators travel by plane, boat, or jeep to reach remote communities that are often inaccessible by road. In many cases, these outreach visits are the only way that these communities can access high-quality information, counselling and services to meet their sexual and reproductive healthcare needs and chose if and when to have children. Limited exposure to sexual and reproductive health education in tandem with social expectations related to the role of women in society means providers in the country must work to bust myths and address stigma related to contraception. The COVID-19 pandemic has only exacerbated poor health outcomes. The country also has some of the worst rates of gender-based violence globally, with some statistics estimating that 2 out of 3 women in PNG have experienced gender-based violence, rates of which have been worsened by the pandemic. MSI Asia Pacific works at a government level, community level, and individual level, to advocate for policy change, increase education, confront bias, and better deliver care. Involving faith leaders and men and boys in sexual and reproductive health education (balanced carefully with women and girl's autonomy to make their own reproductive decisions) de-stigmatizes services.  LinksMSI Asia Pacific MSI Asia Pacific on TwitterMSI Asia Pacific on FacebookMSI Asia Pacific on InstagramMSI Asia Pacific DonationsSupport the show (https://www.reprosfightback.com/take-action#donate)

ASCP Esty Talk
Ep 114 – The Rogue Pharmacist: Star Supplements to Boost the Barrier Function

ASCP Esty Talk

Play Episode Listen Later Apr 29, 2022 25:55


Ep 114 – The Rogue Pharmacist: Skin Barrier Function The skin has many functions but perhaps the most important is its permeability barrier, limiting water loss and preventing the penetration of harmful elements from the environment. Ceramides, lipids, and antioxidants all play a role in the health and function of the skin. In this episode of The Rogue Pharmacist with Benjamin Knight Fuchs, we discuss these star supplements to include in your skin care regimen as well as to take topically to support and boost the barrier function. Associated Skin Care Professionals (ASCP) presents The Rogue Pharmacist with Benjamin Knight Fuchs, R.Ph. This podcast takes an enlightening approach to supporting licensed estheticians in their pursuit to achieve results-driven skin care treatments for their clients. You can always count on us to share professional skin care education, innovative techniques, and the latest in skin science. Benjamin Knight Fuchs is a registered pharmacist, nutritionist, and skin care chemist with 35 years of experience developing pharmacy-potent skin health products for estheticians, dermatologists, and plastic surgeons. Ben's expert advice gives licensed estheticians the education and skin science to better support the skin care services performed in the treatment room while sharing insights to enhance clients' at-home skin care routines.   Connect with Ben Fuchs:    Website: www.brightsideben.com    Phone: 844-236-6010    Facebook: www.facebook.com/The-Bright-Side-with-Pharmacist-Ben-Fuchs-101162801334696/    About Our Sponsor:   LAMPROBE The popular and revolutionary LAMPROBE utilizes radio and high-frequency technology to treat a wide variety of Minor Skin Irregularities™ (MSI)—non-invasively—with instantaneous results. Common conditions treated by the LAMPROBE include: vascular MSI, such as cherry angiomas; dilated capillaries; sebaceous MSI, including cholesterol deposits and milia; and hyperkerantinized MSI, such as keratoses and skin tags.   The LAMPROBE uniquely assists modern, capable, and skilled skin care practitioners to do their work more effectively and with greater client and professional satisfaction. Setting standards in quality, education, and training, the LAMPROBE has become an essential tool enabling skin care practitioners around the world to offer new revenue-enhancing and highly in-demand services.   Website: www.lamprobe.com   Email: info@lamskin.com   Phone: 877-760-2722   Instagram: www.instagram.com/lamprobe   Facebook: www.facebook.com/theLAMPROBE  

Hotline League
EG's FIRST LCS TITLE! Who carried them?! Is NA talent the FUTURE of LCS? | HLL 219

Hotline League

Play Episode Listen Later Apr 28, 2022 123:08


00:00:00 Intro 00:17:40 Travis's fan polls 00:31:09 Fez wants to talk about how Danny and Jojo were the worst 2 players on EG 00:45:10 Alienware break! 00:46:32 Snailchip thinks this is the first time in a while the LCS has storyline potential 01:04:30 Timmychanga says EG did NOT prove that NA talent is the future of LCS 01:15:47 Grubhub break! 01:19:15 Izzdaer's take: Jojo at MSI in his first split will be a buff 01:32:05 LooterJoe's take: 100T should blow up the team after summer split 01:42:20 kito's take: C9 is making a mistake if they ditch the summit project 01:51:30 Emily calls in to add context to her scouting statement 02:01:20 Outro

W2M Network
The MSI Field is Set

W2M Network

Play Episode Listen Later Apr 27, 2022 116:17


Now all of the regional playoffs are complete, we know our full field for the 2022 Mid-Season Invitational. The groups are drawn, and there's chatter about the ping rate, but we're here to give our thoughts on what the big question is: who's gonna win? Plus, there's already a handful of changes on both rosters and coaching staffs, so Andesian will break those down and see what it could mean ahead of Summer Split. The full article about kkOma and his Korean head coaching role is here: https://www.invenglobal.com/articles/17019/update-apr-22-kkoma-announces-intention-of-resignation-from-team-koreas-head-coach-position You can watch the video version on YouTube here: https://youtu.be/6KJ9aPPv3wk While you're here, join us on Discord! https://discord.gg/aydMgvUN9d

Summoning Insight
Evil Geniuses and RNG win titles / NA talent on the rise? (feat. Dagda)

Summoning Insight

Play Episode Listen Later Apr 25, 2022 213:23


Join MonteCristo and Thorin with guest Robert "Dagda" Price, LPL color caster and analyst, as they discuss the LPL and LCS finals, Evil Geniuses and RNG's victories, the rise of NA players jojopyun and Danny, previewing MSI, the upcoming Asian games qualifiers, the chances of G2 and T1 and MSI, and more. This episode was filmed on April 25th, 2022.

The Dive - A League of Legends Esports Podcast
The Dive | Report Cards, Predictions and Playoffs

The Dive - A League of Legends Esports Podcast

Play Episode Listen Later Apr 7, 2022 85:49


Hey there Dive fans! With playoffs fully in swing, we've got another jam-packed episode from our usual gang, Azael, Kobe, and Mark. They discussed each of their Power Ranking Records (shoutout to @lolpodcastmeta for the breakdown via twitter), whether player report cards were actually motivating players, and discussed Danny's status with playing Champions Queue. Then we shifted over to questions from fans (yes, you!) regarding which team should be sent to MSI, The Dive's take on what C9 needs to practice to make a lower bracket run, C9 vs GG, and the best top laners. A reminder that tickets are on sale for the Spring Finals in Houston, you can get information on how to get your set of tickets here: https://twitter.com/LCSOfficial/status/1507401972437057541?s=20&t=ySRE4Hc5BlHq0c8rr7FH5w As always, we appreciate the questions we got this week, and the more you send in questions with #TheDiveLol on Twitter or on Anchor.fm, the more we can feature them on episodes. Playoffs continue this weekend with Cloud9 vs Golden Guardians on Saturday 4/9 at 1:30pm PDT, and Evil Geniuses vs FlyQuest on Sunday 4/10 at 12:30pm PDT. Make sure to tune in! --- Send in a voice message: https://anchor.fm/the-dive-esports-podcast/message