Podcasts about Paradigm

In this message we continue our series, Good 4 U, by seeing what the Word says about how to choose the relationships in your life.

#141Josh sits down with Maddy Shannon, Head of Product Strategy at SpotOn, who has spent her career making independent restaurants more profitable. From a start at Bain, to the business team at The Alinea Group under Nick Kokonas, to the finances at SingleThread Farms in Healdsburg, to a Stanford MBA and now leading SpotOn's reporting, Profit AI, and analytics teams, Maddy sits at the rare intersection of hospitality and product. The conversation keeps circling one idea: great hospitality and great product design solve the same problem. Both anticipate what someone needs before they ask, and both disappear when they work. She calls it the invisibility problem, and it reframes everything from how a point of sale should feel to why diners undervalue what a restaurant gives them.The two dig into what a restaurant meal is really worth, and why pricing a plate off the cost of the prawns misses the wine glass that gets refilled and the person clearing your crumbs. Maddy floats David Nayfeld's idea of billing a meal the way a plumber does, materials, labor, total, so guests see what they are paying for. From there it turns to leadership, where she sets Nick Kokonas's clarity of vision against Kyle Connaughton's prove me right approach at SingleThread, and Josh on unlearning twenty years of knowing every station when he moved into tech. On AI, they land on the line that anchors the back half: data is plentiful, attention is scarce. Both agree the real unlock is not another dashboard but software that tells an operator what to do, the way a doctor diagnoses rather than asking where it hurts. It closes on mastery, the donabe rice pot Maddy treasures, and the tension that restaurant economics rarely leave a chef room to master one thing. Her parting advice: next time you sit down to eat, take a beat, look around, and do not look at the prices so closely.Links and resources

ReferencesPNAS. 2011. May 24| vol. 108 | no. 21 .E118–E127 Discov Immunol. 2024 Nov 19;3(1):kyae016Cureus. 2025 Sep26;17(9):e93294Cell Reports Medicine 2022. Volume 3, Issue 3, 15 March 100543Discov Immunol. 2024 Nov 19;3(1):kyae016.Guerra, DJ. 2026 Unpublished LecturesMcQuinn,ParsonsKelly, Hillman, Dylan, Haggard.1968.Sweetheart of the Rodeo .lp .Byrdshttps://music.youtube.com/playlist?list=OLAK5uy_kejb97oJ9VJCssjIxpz2YeHK9htTy-wz0&si=XNJafnmA_B64KHcs

ReferencesGuerra, DJ.2026. Unpublished LecturesMcClean, D. 1971 American Piehttps://open.spotify.com/track/1fDsrQ23eTAVFElUMaf38X?si=05a7bcbf872c4220

This sermon examines Luke 17 to illustrate the proper relationship between believers and God as unworthy servants responding to divine mercy. The preacher contrasts the nine ungrateful lepers with the one Samaritan who returned in faith to give thanks, highlighting that true worship stems from recognizing one's spiritual uncleanness and dependence on Christ. Central to the message is the conviction that Jesus cures sinners not because they are worthy, but out of His sovereign grace. The text emphasizes that genuine saving faith inevitably produces a heart of gratitude and reverent obedience. Believers are called to abandon prideful entitlement and instead approach God with humble petitions for mercy and loud praise for His salvation.

Was justice served properly? Is there a case to be made for any of the Pikeville Six to be released? Thanks for listening to season one of Paradigm. Be sure to subscirbe to this show so that you receive updates on new season releases, bonus content, and more. For licensing information, follow the link below. All sounds and clips are used with permission or on a fair use basis.https://docs.google.com/document/d/17QJcVK3kEfoSvp9GGM3YITa4kTWvT5VE/edit?usp=share_link&ouid=114163905137206803311&rtpof=true&sd=true This is a B + B Creative Production. Podcast distributed by Stove Leg Media.  --For early, ad free episodes and monthly exclusive bonus content, join our Patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

ReferencesDiscov Immunol. 2024 Nov 19;3(1):kyae016Cell Reports2015 Volume 13, Issue 1p132-144October 06, Guerra. DJ.2026.Unpublished Lectures.Hayward/Pinder/Thomas/Edge.1969. To Our Children's Children Moody Blueshttps://music.youtube.com/playlist?list=OLAK5uy_nUbo_GZxI3GafKmIJazCD_XP1LSA5bRX4&si=sFMKnz_osf0rlmmu

ReferencesDiscov Immunol. 2024 Nov 19;3(1):kyae016Cell Metab. 2012 Jun 6;15(6):813-26. Dev Comp Immunol . 2020 Aug:109:103694. Guerra, DJ.2026. Unpublished LecturesMozart, WA. 1791. String Quintet in E-flat major, K. 614.https://music.youtube.com/watch?v=hEFu9iV0Zxw&si=xmWnzWorPG9Xtqzy

John and Jamie discuss the punishments for the Pikeville six. For licensing information, follow the link below. All sounds and clips are used with permission or on a fair use basis.https://docs.google.com/document/d/17QJcVK3kEfoSvp9GGM3YITa4kTWvT5VE/edit?usp=share_link&ouid=114163905137206803311&rtpof=true&sd=true This is a B + B Creative Production. Podcast distributed by Stove Leg Media.  --For early, ad free episodes and monthly exclusive bonus content, join our Patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Olivia Fox Cabane reveals the behaviors and practices that help develop your personal charisma.— YOU'LL LEARN — 1) The number one myth surrounding charisma 2) How to amplify your presence in just a few seconds3) The master key to looking and feeling more powerfulSubscribe or visit AwesomeAtYourJob.com/ep1167 for clickable versions of the links below. — ABOUT IAN — Olivia Fox Cabane is a leading authority on the science of charisma and the bestselling author of The Charisma Myth and The Net And The Butterfly, translated into 36 languages. Formerly Director of Innovative Leadership for Stanford StartX, she has lectured on charisma, leadership, and innovation at Harvard, Yale, MIT, the Marine War College, and the United Nations. As cofounder of the KindEarth.Tech Foundation, she supports foodtech companies advancing environmental sustainability. Her clients include the leadership of Apple, Google, TikTok, Deloitte, UBS, and JP Morgan as well as founders of Airbnb, Brex, Paradigm, and Presight. She has been featured in The New York Times, The Economist, and The Wall Street Journal. • Book: The Charisma Myth: How Anyone Can Master the Art and Science of Personal Magnetism• Meditation: The Charisma Myth Exercises: Metta• Website: AskOlivia.com— RESOURCES MENTIONED IN THE SHOW — • Study: “Case Report: Women, Be Aware that Your Vocal Charisma can Dwindle in Remote Meetings” by Ingo Siegert and Oliver Niebuhr• Study: “Organizational Behavior and Human Decision Processes” by Jane M. Howell and Peter J. Frost• Study: “Predictors of leadership: The usual suspects and the suspect traits” by John Antonakis• Researcher: Dr. Oliver Niebuhr• Microphone: Maono HD300T• YouTube: Podcastage• Book: Influence: The Psychology of Persuasion by Robert Cialdini• Book: Radical Acceptance: Embracing Your Life With the Heart of a Buddha by Tara Brach— THANK YOU SPONSORS! — • Shopify. Sign up for your free trial at Shopify.com/awesomepod• Monarch. Get 50% off your first year with code AWESOME at Monarch.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Last night we kicked off our brand new series, Good 4 U!

ReferencesGastroenterol Res Pract. 2025 Feb 26;2025:4950214Guerra, DJ. 2026. Unpublished LecturesStaines, B.1979 The Logging Songhttps://open.spotify.com/track/23NH1l9Gn2RmAtMYt9oLfr?si=88a409a32f364989

Jamie and John explore whether the Pikeville six were truly worshipers of Satan. Could they be have been simply misguided young folks who were into things that a number of teenagers in 1997 were into? For licensing information, follow the link below. All sounds and clips are used with permission or on a fair use basis.https://docs.google.com/document/d/17QJcVK3kEfoSvp9GGM3YITa4kTWvT5VE/edit?usp=share_link&ouid=114163905137206803311&rtpof=true&sd=true This is a B + B Creative Production. Podcast distributed by Stove Leg Media.  --For early, ad free episodes and monthly exclusive bonus content, join our Patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

ReferencesFront Immunol. 2020 Jul 8;11:1024Neural Regen Res. 2019 Apr;14(4):595–596.Guerra, DJ. 2026. Unpublished LecturesLennon/McCartney. 1966 Good Day Sunshine. Beatleshttps://open.spotify.com/track/7HTH1ppjkkOe7RLoBDKXYJ?si=81b7d875d47a48ee

Jamie Gieseke, Paradigm FuturesSee omnystudio.com/listener for privacy information.

 Jamie and John discuss the stories of Jason Bryant, Dean Mullins, and Joseph Risner. For licensing information, follow the link below. All sounds and clips are used with permission or on a fair use basis.https://docs.google.com/document/d/17QJcVK3kEfoSvp9GGM3YITa4kTWvT5VE/edit?usp=share_link&ouid=114163905137206803311&rtpof=true&sd=true This is a B + B Creative Production. Podcast distributed by Stove Leg Media.  --For early, ad free episodes and monthly exclusive bonus content, join our Patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Connect with Early Riders — https://www.earlyriders.com/contactConnect with Onramp — https://onrampbitcoin.com/contact-us/Presented collaboratively by Early Riders & Onramp Media…Final Settlement is a weekly podcast covering capital markets, dealmaking, early-stage venture, bitcoin applications and protocol development.This week Michael, Liam, and Brian break down the banks' accelerating tokenization push: BlackRock, Goldman Sachs, and JPMorgan joining a 54-firm UK tokenization task force, Swift's blockchain ledger pilot with 17 banks, and what it means for Bitcoin's role in the emerging plumbing. They dig into Satya Nadella's AI sovereignty thesis, Microsoft's Frontier Company data play, Apple's lawsuit against OpenAI, and the Fed's new AI task force under Kevin Warsh. The guys run through a stack of deals: TerraWolf's $19 billion Anthropic infrastructure agreement, OLAMA's $65 million raise, Paradigm's $1.2 billion fourth fund expanding into AI and robotics, and Tether's $20 million investment in Mercado Bitcoin. They close on TradFi's crypto expansion via SBI Holdings and Russia's Alpha Bank, Kraken's $22 million lawsuit win, where the Clarity Act stands ahead of the midterms, and Spiral's new open source push to merge Bitcoin and AI.Chapters00:00 - Introduction and Show Overview00:18 - Market Sentiment and Show Focus01:15 - Banks and Traditional Enterprises in Digital Asset Space02:40 - UK Tokenization Task Force and Use Cases03:40 - Swift Blockchain Ledger Pilot with 17 Banks04:34 - Global Sprint in Tokenized Securities and Deposits07:23 - Bitcoin's Role in the Future of Digital Infrastructure09:39 - The Bullish Case for Bitcoin Amidst Tokenization12:28 - AI Tools and Sovereignty in Data Ownership15:37 - Microsoft's Investment in AI and Data Sovereignty22:16 - Microsoft Frontier Company and Proprietary Data Platforms25:07 - The Importance of Human Agency in AI Adoption28:40 - AI and the Disruption of Traditional Business Models29:08 - Apple Suing OpenAI Over Trade Secrets32:36 - The Long-Term Impact of AI and Open Source Models36:50 - DoorDash's AI Code Reviewer and Internal AI Adoption38:19 - Fed's AI Task Force and Economic Policy43:32 - Russia's Strategic Use of Bitcoin and Digital Assets50:07 - Paradigm's New Fund and Broader Tech Investment55:13 - Traditional Finance's Entry into Crypto and Digital Assets01:02:41 - Regulatory Developments and the Future of Crypto Legislation01:09:18 - Bitcoin's Role in the Future of Digital Infrastructure01:11:21 - Open Source AI and Bitcoin IntegrationIf you found this valuable, please subscribe to Early Riders Insights for access to the best content in the ecosystem weekly: https://www.earlyriders.com/researchKeep up with Michael:https://x.com/MTangumaKeep up with Liam:https://x.com/Lnelson_21Keep up with Brian:https://x.com/BackslashBTC

How has new research changed the way we see nutritional health? What role do ultra-processed foods, fibre, gut microbes, inflammation and insulin resistance play in the new paradigm? Why does the gut microbiome affect our mental health? How can simply diversifying the quantity of plants in your diet change health outcomes radically?In this episode we have the complex topic of nutrition to get up to date on. There's been so much research over the last 20 years that has contradicted some of our most deep seated preconceptions about food, so today we clarify science's new take. We discuss the rise of lifestyle medicine as a solution to western health crises; individualised diet; ultra processed foods; fibre; glycemic index issues; the gut microbiome; inflammation; a variety of foods over restrictive diets; how to support the use of new GPL-1 weight loss drugs; and what the nutritional organisation Zoe is doing to make this all easier for the public to put into practice.Fortunately our guest is a master at untangling all this nuance in a way that's so easy for us Joe public to understand - medical scientist and clinical nutritionist, senior lecturer and researcher at Imperial College London and King's College London, Dr. Federica Amati. She's also Head Nutritionalist at ZOE and Head of Nutrition Science at WellFounded Health. She's written 12 scientific papers and 3 books, “EveryBODY should know this”, “Recipes for better menopause”, and her brand new book “The Appetite reset”, which we discuss today.What we discuss: 00:00 Intro06:30 Worldwide pandemic of previously western-only diet related chronic diseases.07:00 Western diet, exported to the rest of the world is a big part of the problem.08:45 Sedentary lifestyle is also part of the metabolic dysfunction crisis.09:15 The “Diabesity” crisis.10:15 Dysfunctional food environments.10:55 One size dos NOT fit all for diet.11:45 Influencers are confusing the public.16:25 Personalised diet issues: more required from the patient, more expensive.18:00 Ultra-processed foods damage 1: quick energy uptake.20:30 U.P.F. damage 2: High palatability - more delicious, harder to stop eating.21:45 U.P.F. damage 3: Synthetic additives - unknown consequences & cocktail effect.23:35 Processed food risk scale from Zoe nutrition can help people consider.24:15 %60 of Uk calories are coming from ultra processed food.30:45 Fibre - How much do we eat and should we eat?32:45 Plant diversity: 30 per week, leads to Intestinal microbe diversity.35:15 Mapping the microbiome. 39:05 Microbiome and mental health - Vagus gut-brain axis, 42:55 Inflammation theory of depression - withdraw from society to heal.43:50 Chronic inflammation caused by western diet and stress.46:45 Your habits are more important than exceptions.48:15 Restrictive calorie-counting diets aren't sustainable for losing weight because of metabolic adaptation.52:05 “The Appetite Reset” book - GLP1 weight loss drugs.56:45 Adult obesity has doubled, adolescent obesity has quadrupled.References:Federica Amati, “The Appetite reset”.Federica Amati, “EveryBODY should know this”.Francesco Asnicar et al.,'Gut micro-organisms associated with health, nutrition and dietary interventions' paper. Zoe Nutrition - microbiome testing, glycemic monitoring, and personalised diet guidance.The microbiome, mental health & rethinking hygiene - Dr. Graham Rook episodeMood Food: The gut, diet and inflammation - Alex Laird episodeNot all U.P.F's are equal - Zoe Nutrition article

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ReferencesFront Immunol. 2025 Dec 3;16:1712452.Nat Commun. 2024 Nov 12;15:9803. Guerra, DJ.2026.Unpublished LecturesMiller, S. 1970. Steven Miller Band Vhttps://music.youtube.com/playlist?list=OLAK5uy_mMurbyyiMLz7bvTAJmI_j8sCs_e-NbvAM&si=0i95A7H0jAkW7AU2

This is a replay of a live Called to Lead info session Kelly hosted with co-founder Sandi Glandt, to answer the questions everyone's been asking: what is Called to Lead, who is it for, and how do you know if you should be in the room? Because it was recorded live, you'll hear real-time Q&A and references to ticket availability, pricing, and dates that were accurate as of the session. Called to Lead is built on faith, family, and freedom, a new success paradigm for ambitious women who refuse to believe they have to choose between a wildly successful business and a rich, faith-centered life. In this session, Kelly and Sandi share the story behind the movement, the gap they saw in a space full of bro-marketing pitch fests and rah-rah woo events, and exactly what to expect at the 2026 flagship event on October 1st in Boca Raton, plus the special Diamond day in Miami on October 2nd. You'll hear the full speaker lineup revealed so far, the ticket tiers and what's included, the year-round community and micro events, and a first look at the brand-new philanthropic arm of the movement. Inside this session: The origin story and the three (really four) pillars: faith, family, freedom, and fitness The full two-day event breakdown and who's in the room The speakers announced so far and why each was chosen How to get involved year-round, and the new Dress for Success partnership Timestamps   02:00 — The origin story and the gap Kelly and Sandi saw 05:00 — The pillars: faith, family, and freedom 09:00 — A litmus test: does this describe you? 12:00 — Why proximity beats consuming more content 15:00 — Called to Lead 2026: connection, collaboration, elevation 18:00 — The two-day format (Boca Oct 1, Miami Diamond day Oct 2) 22:00 — Who's in the room: 500+ women from around the globe 24:00 — The live speaker lineup 36:00 — The year-round community and micro events 39:00 — Ticket tiers, pricing, and what's included 43:00 — The new philanthropic arm: Dress for Success RESOURCES + LINKS Called to Lead 2026:  grab your ticket for the the flagship women's leadership and business growth event. Day 1: October 1, 9:00 AM–6:00 PM, Boca Raton Innovation Campus. Day 2 (Diamond experience): October 2, 1:00–4:00 PM, The Moore, Miami. Ticket tiers: Diamond, VIP, General, and Virtual, with payment plans and bulk/bundle options available:  www.sandiglandt.com/called-to-lead  Keep up with the Called to Lead Movement onInstagram, where event and speaker announcements are shared: https://www.instagram.com/calledtoleadmovement 

John and Jamie interview an advocate for Karen Howell and a few of Satan's Six in this exclusive interview. For licensing information, follow the link below. All sounds and clips are used with permission or on a fair use basis.https://docs.google.com/document/d/17QJcVK3kEfoSvp9GGM3YITa4kTWvT5VE/edit?usp=share_link&ouid=114163905137206803311&rtpof=true&sd=true This is a B + B Creative Production. Podcast distributed by Stove Leg Media.  --For early, ad free episodes and monthly exclusive bonus content, join our Patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

ReferencesNature Communications2=18. Vol. 9,Article number: 1228 PLoS One. 2024 Jul 5;19(7):e0304997Guerra, 2026 Unpublished LecturesSquire et al. 1971. Yes. Heart of the Sunrise Yessopngshttps://open.spotify.com/track/3vwjrVDFKelpfuD6yO1oW4?si=821bc04addaf46dd

John and Jamie explore the Satanic Panic and how it could have influenced the investigation and trial of Satan's Six. For licensing information, follow the link below. All sounds and clips are used with permission or on a fair use basis.https://docs.google.com/document/d/17QJcVK3kEfoSvp9GGM3YITa4kTWvT5VE/edit?usp=share_link&ouid=114163905137206803311&rtpof=true&sd=true This is a B + B Creative Production. Podcast distributed by Stove Leg Media.  --For early, ad free episodes and monthly exclusive bonus content, join our Patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Psychology-Paradigm is the red pill book for men on developing dominant masculine presence, frame control, and masculine mindset to transform their relationships with women. Paul Bauer breaks down how to identify the belief systems holding you back, build an unshakeable masculine frame, and stop being on the back foot with women for good.If you've been searching for red pill self improvement books for men that go deeper than surface level dating advice, this is it. Available now on Amazon in hardcover, paperback, and Kindle.➡️ Get it here: https://mybook.to/psychology-paradigm

ReferencesJCI Insight. 2018 Sep 6;3(17):e121630Signal Transduction and Targeted Therapy2022.. 7, : 304 Arthritis Res Ther.2021; 23: 19.MDPI Genes 2021, 12(9), 1313; https://doi.org/10.3390/genes12091313Guerra, DJ.2026. Unpublished LecturesLennon/McCartney. 1965. Wait Rubber Soul Beatleshttps://music.youtube.com/watch?v=qJngWval8Bc&si=9ZTkMl5YuJ870EJ4Lennon/McCartney.1968. Long Long Long White Album. Beatles.https://music.youtube.com/watch?v=e9vUCdfwlgw&si=p-8M8n6bgUurCuq8

Jamie and John explore who the Lillelids were, and how their son Peter has adjusted to life after sufffering this extreme trauma as an infant. For licensing information, follow the link below. All sounds and clips are used with permission or on a fair use basis.https://docs.google.com/document/d/17QJcVK3kEfoSvp9GGM3YITa4kTWvT5VE/edit?usp=share_link&ouid=114163905137206803311&rtpof=true&sd=true This is a B + B Creative Production. Podcast distributed by Stove Leg Media.     --For early, ad free episodes and monthly exclusive bonus content, join our Patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

References Nat Struct Mol Biol . 2006 Dec;13(12):1097-101Open Biol. 2013 Oct;3(10):130144Arthritis Res Ther.2021; 23: 19.European Review for Medical and Pharmacological Sciences 2021; 25: 1425-1435Frontiers in Immunology 2024 09 January DOI 10.3389/fimmu.2023.132280Guerra, DJ. 2026.Unpublished Lectures.Teleman, G P 1716. Concerto in D. TWV51 https://music.youtube.com/watch?v=F5J80v3ACbo&si=oiJxKkpbnLhiZ833Hunter/Garcia.1973. Stella Blue. Grateful Dead.https://music.youtube.com/watch?v=VKsWDyvWaL4&si=Jul71w1djWl2WTIIp. 1716. D1 TWV51.

Jamie and John visit the location of the Lillelid murders and explore the crime details, setting the stage for the rest of season one. For licensing information, follow the link below. All sounds and clips are used with permission or on a fair use basis.https://docs.google.com/document/d/17QJcVK3kEfoSvp9GGM3YITa4kTWvT5VE/edit?usp=share_link&ouid=114163905137206803311&rtpof=true&sd=true This is a B + B Creative Production. Podcast distributed by Stove Leg Media. --For early, ad free episodes and monthly exclusive bonus content, join our Patreon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

ReferencesFrontiers in Immunology 2014. November 21(578):1Clin Epigenetics. 2017; 9: 94. Cancer Cell International 2020. September 20(1):429Guerra, DJ.2026. Unpublished Lectures.Vinsom/Chapman/Burnett. 1930. Sitting On Top of the World Creamhttps://open.spotify.com/track/0aY5bJ4jRHiOd8eCMWmcy8?si=b3c7f2090c6e441cJagger/Richards.1965.Satisfaction Rolling Stoneshttps://open.spotify.com/track/2PzU4IB8Dr6mxV3lHuaG34?si=6b244c676bf1454eLennon/McCartney. 1968 Helter Skelterhttps://open.spotify.com/track/0Bs0hUYxz7REyIHH7tRhL2?si=f345fea1161a4f27Paige/ Plant 1971. Rock and Roll Led Zepplinhttps://open.spotify.com/track/4PRGxHpCpF2yoOHYKQIEwD?si=3203893185c24bee

When Anthropic launched Claude for Legal in May – more than 20 MCP connectors and a dozen practice-area plugins built specifically for legal work – it marked the company's biggest and most explicit commitment yet to the legal industry. It also reignited a debate that's been simmering since Anthropic's first legal plugin briefly rattled the stock prices of Thomson Reuters, RELX and Wolters Kluwer back in January: Is Anthropic's entry into the legal market a major step forward for legal productivity? Or is it a threat to trust, governance and the existing legal-tech infrastructure?   In today's episode, Mark Pike, associate general counsel at Anthropic and product lead for Claude for Legal, joins host Bob Ambrogi to share the inside story of Claude for Legal and his own unconventional path into leading its development. Pike, who went from Facebook to Slack to building internal tools for Anthropic's own legal team, talks about how that work turned into a product that has ignited both excitement and concern throughout the global legal industry. Among the topics they discuss:   Why Anthropic decided legal deserved its own dedicated launch, and why now. What plugins, skills, connectors, cookbooks and agents actually mean in plain English. Why lawyers have become Claude's most active power users. Anthropic's decision to partner, rather than compete, with major legal tech vendors such as Thomson Reuters. How Anthropic thinks about human oversight and professional responsibility. Confidentiality, data training policies, and what firms need to know before adopting these tools. Anthropic's commitment to access to justice. What Claude for Legal might look like a year from now.   Whether you're excited about what this technology could mean for legal innovation, wary of what it means for the future of legal work, or just have questions about how it all works, this conversation offers insights.   Background links: Announcement: Claude for the Legal Industry. Webinar: How Legal Teams Put Claude to Work. Claude for Legal Github Repo. LawSites: Anthropic Goes All-In on Legal, Releasing More Than 20 Connectors and 12 Practice-Area Plugins for Claude.   Thank You To Our Sponsors This episode of LawNext is generously made possible by our sponsors. We appreciate their support and hope you will check them out.   Paradigm, home to the practice management platforms PracticePanther, Bill4Time, MerusCase and LollyLaw; the e-payments platform Headnote; and the legal accounting software TrustBooks. Briefpoint, eliminating routine discovery response and request drafting tasks so you can focus on drafting what matters (or just make it home for dinner). CosmoLex, helping law firms manage their entire practice in one platform, from intake to payment. Try it free.   If you enjoy listening to LawNext, please leave us a review wherever you listen to podcasts.  

ReferencesAtherosclerosis .2012 Mar;221(1):2-11.Antiox and Redox Sig. 2018. March 30(6):813-856Experimental Immunol. 2018.v87. issue 4:e12648Scand J Immunol. 2018 Apr;87(4):e12648Front. Immunol. Sec. Cancer Immunity and Immunotherapy 2025. vol16 05 February Guerra,DJ.2026.Unpublished Lectures.Dvorak. A. 1894. American Suite in A Major. op.98https://music.youtube.com/watch?v=yi37I6w46FM&si=hhBZx2_TqEu9Txmn

References Sci Signal. 2017 Jul 25;10(489)EMBO Rep. 2017 Mar 7;18(4):645-657`Guerra, DJ. 2026. Unpublished LecturesHunter/Garcia, et al.1970. American Beauty lp. Grateful Dead.https://music.youtube.com/playlist?list=OLAK5uy_nc3dHmM6xdsySO1SSxYLYzlm82rVZ1pfM&si=2xOrRK6QpYFeI8Is

ReferencesBiochimica et Biophysica Acta (BBA) 2026 - Molecular Basis of Disease February168069 Volume 1872, Issue 2Comput Math Methods Med. 2012 Sep 16; 2012:173521Front. Immunol.2026. 15 April Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune DisordersVolume 17 - 202Guerra, DJ. 2026. Unpublished LecturesHunter/Garcia.1973. US Blues Grateful Deadhttps://music.youtube.com/watch?v=-IBk5xk5Pec&si=yMHTzyV2p8xsIZly

ReferencesNeuroendocrinology. 2000 Mar;71(3):187-95J Immunol.2014 Jan 3;192(3):979–984.Molecular and Cellular Endocrinology 2018.Volume 472, 5 September: 40-49Front. Immunol., 2023. 16 March Sec. T Cell Biology.Volume 14 -Guerra, DJ. 2026. Unpublished Lectures.Emerson/Lake/Palmer. 1972. Trilogy lp. fullhttps://music.youtube.com/playlist?list=OLAK5uy_m-KrYKLiBdrOau11bsTte7M4qSR0en7VI&si=DwpdwN0nR_IGNsK1

How do you discern the call of God on your life? Sometimes hearing from God can feel difficult. This week, Pastor Jon led us through Acts 16, and the requirements we need to hear God's call for us. 1. We need closed doors. While they can initially seem like lost opportunities, how you navigate closed doors can be what your calling is contingent upon. 2. We need word from God. God often speaks to his people through the Word itself, along with through biblically wise people, dreams, and the Holy Spirit. 3. We need a willing heart to go. God grows a heart that is willing to go, and is waiting on our yes and surrender to his plan. Don't be a Christian who just professes faith, but one who also possesses faith. Remember that faithfulness is the prerequisite to a word from God. We'll see you next Tuesday, Paradigm!

What if your symptoms are not the problem? What if they're actually trying to help you?Today, we explore a different perspective on health, illness and healing. Rather than seeing symptoms as signs that the body is broken, what if they are intelligent messages from a body that is trying to protect, adapt and communicate with you?Sarah shares insights from her own healing journey from autoimmune disease, chronic pain, depression, adrenal exhaustion and other health challenges, as well as what she has learned through years of supporting others on their healing journeys.In this episode, you'll discover:

Last month, when Anthropic, developer of the popular AI assistant Claude, announced a major push into legal, much of the coverage in the media and the buzz on social media focused on what the announcement meant for law firms, in-house legal teams, and the legal tech ecosystem.   But the less talked about side of the story was potentially the more impactful – Anthropic's explicit commitment to access to justice, highlighted by a direct partnership with the Free Law Project and its CourtListener free legal research platform. Suddenly, anyone with a legal problem and a chat window could access verified, authoritative legal materials, significantly reducing the risk of using a general AI assistant to answer legal questions.   As the Free Law Project itself put it: "A response built on verified CourtListener data is categorically different from one built on even the best model alone."   In today's episode, host Bob Ambrogi sits down with Mike Lissner, executive director and co-founder of the Free Law Project, the nonprofit behind CourtListener, and Nathan Dahlberg, the Free Law Project's AI developer who actually built the CourtListener connector. They get into what was announced and why it matters, how the technology works under the hood, and, most importantly, the bigger questions it raises — about the potential impact on access to justice, and on the legal research industry.. Thank You To Our Sponsors This episode of LawNext is generously made possible by our sponsors. We appreciate their support and hope you will check them out.   Paradigm, home to the practice management platforms PracticePanther, Bill4Time, MerusCase and LollyLaw; the e-payments platform Headnote; and the legal accounting software TrustBooks. Briefpoint, eliminating routine discovery response and request drafting tasks so you can focus on drafting what matters (or just make it home for dinner). CosmoLex, helping law firms manage their entire practice in one platform, from intake to payment. Try it free.   If you enjoy listening to LawNext, please leave us a review wherever you listen to podcasts.   Chapters (00:00) Introduction to AI in Legal Tech (03:17) The Free Law Project and CourtListener (05:01) Anthropic's Commitment to Access to Justice (10:29) Understanding MCP Connectors (11:48) Potential Impact on Access to Justice (14:31) The Changing Landscape of Legal Research (17:21) User Interaction with AI Tools (20:00) Concerns About Self-Help Legal Tools (24:00) Marketing Challenges for Legal Tools (27:20) Understanding User Engagement with the Connector (29:00) Grounding AI Responses in Legal Data (30:30) The Future of Legal Research and MCP Connectors (34:10) Commercial Opportunities in Legal AI (38:55) User Experience and Privacy Concerns (43:10) Impact on Access to Justice

In today's episode, we spoke with David O'Malley, MD. Dr O'Malley is a professor in the Department of Obstetrics and Gynecology at The Ohio State University College of Medicine and the director of the Division of Gynecologic Oncology at The Ohio State University Comprehensive Cancer Center–James in Columbus, Ohio. In our exclusive interview, Dr O'Malley discussed his approach to treatment selection and sequencing in platinum-resistant ovarian cancer, a disease setting he described as representing the highest unmet need in the field. He emphasized the central role of clinical trial enrollment and biomarker-driven decision-making, alongside practical patient-centered considerations, such as infusion schedule and quality of life.He highlighted the growing importance of antibody-drug conjugates (ADCs) in this setting, noting that folate receptor alpha and HER2 are the two biomarkers most relevant to current practice. Dr O'Malley outlined how National Comprehensive Cancer Network guidelines support treatment across a broader range of expression levels than initial approvals reflected, citing emerging data suggesting activity even at lower expression thresholds. He also addressed payload sequencing, explaining that outside of a clinical trial, he currently uses topoisomerase I–based ADCs and antimicrotubule-based ADCs each one time only, and remains open to targeting the same antigen again if the payload differs.The discussion also touched on combination strategies, resistance biology, and the evolving role of immunotherapy following the survival benefit observed with pembrolizumab (Keytruda) in the phase 3 KEYNOTE-B96 trial (NCT05116189). Dr O'Malley expressed enthusiasm for next-generation payloads, dual-target approaches, and the potential for bispecific antibodies and novel DNA damage response–targeting agents to define the post-ADC treatment landscape.Finally, Dr O'Malley underscored the need for more tumor biopsies to better characterize resistance mechanisms and called for expanded pharmaceutical investment in retreatment and cross-resistance studies to guide future sequencing decisions.

The 10 Commandments Hyperlink Episode (E15) — Sometimes at the close of a series, we'll dig through the podcast archives to find clips that discuss similar ideas from a different perspective. In this 10 Commandments series, we explored how trusting in God's wisdom leads to true life and flourishing, while building lives on our own terms often leads to pain. So in this hyperlink episode, we'll listen to three clips that explore this theme further. First, Jon and Tim break down the literary structure of the stories surrounding the 10 Commandments, which highlight humanity's reluctance to wait on God's commands. Second, Jon, Tim, and former BibleProject scholar Carissa Quinn look at how the golden calf story in Exodus 32 relates to the 10 Commandments. And finally, Jon, Tim, and Carissa discuss how all of the Bible's poems, narratives, laws, and letters are wisdom for us. CHAPTERS The Literary Structure of Exodus 19-24 (0:00-11:32) Obeying God on Our Terms (11:32-31:10) Commandments in a Modern Context (31:10-47:10) REFERENCED RESOURCES Find the 10 Commandments full collection of resources here. Clip 1 is from “Testing at Mount Sinai,” episode 6 in our 2022 series, Exodus Scroll. Clip 2 is from “A God of Our Own Making,” episode 2 in our 2020 series, Character of God. Tim reads quotes from both the Talmud (sometimes referred to as the Babylonian Talmud) and Midrash Exodus Rabbah in the discussion about the golden calf of Exodus 32. Clip 3 is from “Wisdom for Life's Complexity,” episode 8 in our 2021 series, The Paradigm. Find the 10 Commandments full collection of video, podcast, and written resources here. Check out Tim's extensive collection of recommended books here. SHOW MUSIC “The Shepherd” by Lofi Sunday feat. Marc Vanparla “Just Truth” by Lofi Sunday feat. Yoni Charis BibleProject theme song by TENTS  SHOW CREDITS Production of today's episode is by Lindsey Ponder, producer, and Cooper Peltz, managing producer. Tyler Bailey and Aaron Olsen edited today's episode and provided the sound design and mix. JB Witty writes the show notes. Our host for today is Michelle Jones. Our creative director is Jon Collins, and our lead scholar is Tim Mackie. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

There is a microphone, a clock, and sixty seconds. What you do with them is entirely up to you. Ten episodes in, Paradigm Drift has become something nobody planned: a living laboratory where the wild, the rigorous, and the genuinely unclassifiable share the same stage. This time the theories range from epigenetic operating systems and fractal cosmology to edge theory, tulpamancy, and the slow dismantling of dark energy. Each one delivered under the gun, each one taken seriously. Pull up a chair; the floor is yours.PARADIGM DRIFThttps://demystifysci.com/paradigm-drift-showPATREON https://www.patreon.com/c/demystifysciPARADOX LOST PRE-SALE: https://buy.stripe.com/7sY7sKdoN5d29eUdYddEs0bHOMEBREW MUSIC - Check out our new album!Hard Copies (Vinyl): FREE SHIPPING https://demystifysci-shop.fourthwall.com/products/vinyl-lp-secretary-of-nature-everything-is-so-good-hereStreaming:https://secretaryofnature.bandcamp.com/album/everything-is-so-good-here00:00 Go! 00:01:56 Paradigm Drift X!00:03:55 How the 60-Second Theory Format Works00:10:01 Time as an Emergent Property00:21:28 Epigenetics as an Operating System00:38:54 Archetypes, Synchronicity, and Quantum Behavior00:53:46 Dark Energy as a Time Illusion01:07:08 Discrete Spacetime and Frequency as Foundation01:37:30 Edge Theory: Geometry, Mass, and Discrete Time01:54:37 Noetics, Embodiment, and Constructed Consciousness02:15:07 Fractal Geometry as Physics' Missing Principle02:35:04 Physics, Mysticism, and Where They Converge#paradigmdrift #philosophy #physics #consciousness #epigenetics #fractals #quantummechanics #naturalphilosophy #cosmology #timeMERCH: Rock some DemystifySci gear : https://demystifysci-shop.fourthwall.com/AMAZON: Do your shopping through this link: https://amzn.to/3YyoT98DONATE: https://bit.ly/3wkPqaDSUBSTACK: https://substack.com/@UCqV4_7i9h1_V7hY48eZZSLw@demystifysci RSS: https://anchor.fm/s/2be66934/podcast/rssMAILING LIST: https://bit.ly/3v3kz2S SOCIAL: - Discord: https://discord.gg/MJzKT8CQub- Facebook: https://www.facebook.com/groups/DemystifySci- Instagram: https://www.instagram.com/DemystifySci/- Twitter: https://twitter.com/DemystifySciMUSIC: -Shilo Delay: https://g.co/kgs/oty671

Sources:https://substack.com/@returntotradition1Contact Me:Email: return2catholictradition@gmail.comSupport My Work:Patreonhttps://www.patreon.com/AnthonyStineSubscribeStarhttps://www.subscribestar.net/return-to-traditionBuy Me A Coffeehttps://www.buymeacoffee.com/AnthonyStinePhysical Mail:Anthony StinePO Box 3048Shawnee, OK74802Follow me on the following social media:https://www.facebook.com/ReturnToCatholicTradition/https://twitter.com/pontificatormax+JMJ+#popeleoXIV #catholicism #catholicchurch #catholicprophecy#infiltration

The lights are on, the BPM is up, and summer nights are calling. TOSHI TYLER brings a nonstop mix of high-energy Euro dance anthems, uplifting vocals, and feel-good club favorites from start to finish. Turn it up and enjoy the ride. Tracklist Midnight Sun, Girls Trip – Zara Larsson, PinkPantheress Desire – Dimension, Sub Focus Voyage Voyage – Klaas, Rocco, Michael Roman I Swear – Mila Falls, Josh Hunter Hot N Cold – Mazza, Klaas, Michael Roman Party Like It's 99 – Jimmy Clash, Dirty Signal Les Dangereux – Reinier Zonneveld, Kiki Solvej All Night – Ceres, Paradigm, Lavinia Insomnia – Restricted, NIKSTER Every Time I Touch You – Mondello'G, Distrion, Sarah De Warren Rock My Body – R3HAB, Inna, Sash!

Send us Fan MailAlyssa feels stress around fireworks that will happen on the 4th of July  - she shares information to create awareness of the devastating effects they have to the planet - offers a mantra and prayer for healing Mother Earth - please see links below:Effects of FireworksEffects of Fireworks on AnimalsArticle in New York TimesSupport the showInstagram

In this message we tackled a big question: What happens to people who never hear about Jesus? Walking through Romans, we were reminded that God has made Himself known through creation. Yet all of us have rejected Him, fallen short of His glory, and stand in need of a Savior. The bad news is that everyone is guilty. The good news is that everyone can be saved. Not by good works. Not by religion. Not by trying harder. We are justified by grace through faith in Jesus alone. But the message doesn't stop there. Romans 10 reminds us that everyone who has put their faith in Jesus has been given a mission: make Him known. We are called to bring the hope of the gospel to the people around us. This week's challenge was simple: Find someone who is spiritually lost. Invite them into your life. Build a genuine relationship. Ask them about their faith. The gospel is too good to keep to ourselves.

Sol LuckmanHere's a fun fact.If you lived in an old-school shamanic society and went to the local medicine person complaining of feeling completely drained or disheartened, the first line of questioning probably wouldn't be about your physical symptoms.It's highly unlikely anyone would check your blood pressure, ask about your sleep hygiene, or verify that your retirement fund was safe.Instead, according to author Gabrielle Roth, you'd more likely be asked one or more of four seemingly unrelated—to the Western mind anyway—questions:When did you quit dancing?How long ago did you stop singing?When was the last time you were enchanted by a story?When did you last find comfort away from the madding crowd in your own silence?This is Sol Luckman, and you're listening to SOL SPEAKS.Today I invite you to shift your paradigm in terms of what causes illness and what we can do ourselves to address many of our own health and mental health problems.The diagnostic framework that allopathic medicine is based on views our modern epidemic of exhaustion as just some sort of “chemical imbalance.”But what if, instead, we're looking at something else entirely?What if we're confronted with a severe and dangerous loss of connection to the fundamental physical rhythms of being human?Before we really get cranking, I want to let you know that if you're a paying member of solluckman.substack.com and find yourself listening there, make sure you scroll down to download your free PDF companion to this podcast, “The Quantum Disco.”Moving (or should I say, grooving?) on now …In today's deep dive, I'm honored and thrilled to have you with me as I explore actionable strategies for getting back our groove—individually and even collectively—in a world that seems stuck in a deep, dark rut of its own.Some of this material will be intense in the way it invites profound and possibly uncomfortable introspection as to why so many of us in modern society feel so fundamentally drained by it.I'm going to look at the architecture of daily anxiety, and even more importantly, I promise to unpack a surprisingly ancient and eminently physical antidote to this problem.This podcast builds on my most recent book, GET OUT OF HERE ALIVE, and also looks forward to the forthcoming sequel that I believe will absolutely knock your socks off.If you'd like to receive an Advance Review Copy of this new book that isn't yet published in exchange for sharing your honest review when it's publicly available, just visit www.crowrising.com and sign up.I can hardly wait to share this brand-new book with the world. I plan to give paid subscribers sneak peek access in the form of a cover reveal in addition to snippets from and other material related to this new book in my exclusive, members-only Substack chat.If you want to show your support and stay in the loop of this and other projects, please be sure to hit the subscribe button right after you like this episode.So, are you ready to challenge how you view your daily routines and ruts, your devices and vices, your screens and perhaps even your mental and emotional burnout?Okay then. Let's dance! Thank you for subscribing. Leave a comment or share this episode.

Once upon a time, a legal tech vendor's goal in getting seen by potential customers was to rank on the first page of Google search. But in the age of AI, that is no longer enough. Now, when a potential buyer asks ChatGPT, Claude or Gemini to recommend a vendor, what matters is whether the company shows up in the answer the AI generates. And that, increasingly, depends on who is quoting you, citing you, and treating you as the authority in your category.   On this episode of LawNext, host Bob Ambrogi talks with two legal marketing and communications leaders who are seeking to help their clients get ahead of that shift. Amy Juers is CEO of Edge Marketing, a firm she founded in 1997 that serves clients across legal technology and accounting. Valerie Chan is CEO of Plat4orm, a strategic communications firm working across legal, cybersecurity, AI, and other regulated industries.   Last week, these longtime competitors announced a strategic partnership and a new framework they call the Trusted Answer Growth System, designed to help companies adapt to how buyers research and shortlist vendors in AI-driven search.   In the conversation, Amy and Val discuss how generative AI is reshaping the buyer's journey, why earned media and third-party credibility carry more weight than ever, the new vocabulary marketers are wrestling with — from GEO to AEO — and what companies can do when AI tools get their story wrong. They also explain why, after years of competing, they concluded they were better off working together.   Thank You To Our Sponsors This episode of LawNext is generously made possible by our sponsors. We appreciate their support and hope you will check them out.   Paradigm, home to the practice management platforms PracticePanther, Bill4Time, MerusCase and LollyLaw; the e-payments platform Headnote; and the legal accounting software TrustBooks. Briefpoint, eliminating routine discovery response and request drafting tasks so you can focus on drafting what matters (or just make it home for dinner). CosmoLex, helping law firms manage their entire practice in one platform, from intake to payment. Try it free.   If you enjoy listening to LawNext, please leave us a review wherever you listen to podcasts.  

After seven years and nearly 300 episodes, I'm trying something I don't think anyone else is doing: giving you all of my Polyvagal Theory knowledge, directly. And free.Season 2 of the Stuck Not Broken podcast is different from the regular show. It's the full audiobook of my first book, Stuck Not Broken: Book 1 - Trauma & the Polyvagal Paradigm, read chapter by chapter, right here in the feed. No book to buy. No course. Just the whole thing.If you've ever wanted to actually understand your nervous system, what it's doing and why, this is the place to start. By the end of the audiobook, you'll have written a new, simple self-narrative and be ready for the next phase of your unstucking journey. No quick fixes. No hacks. No gimmicks.

"That's bulls***." That was my honest first reaction, back in 2018, to the work I now build my entire career around.In this episode of the Stuck Not Broken audiobook, I invite you to challenge your paradigm:How I came to Polyvagal Theory, and nearly dismissed itWhat a paradigm is, and why you need a new one before the science can landThe urge most of us feel to skip ahead to the fix, and why there isn't one to skip to