Podcasts about ocular

Welcome back to your two favorite girlies!! Today we had an INCREDIBLE guest that truly left us inspired.    We talk with Paulette about aging, being courageous to take chances, and to rebrand your life!! We can't wait for you to hear this episode and leave it feeling as inspired as we both were.    About our guest: Paulette Szalay at the age of 57 weighed 264 pounds at the height of 5'4". She survived an ocular stroke and three and half years later, at the age of 61, Paulette lost 148 pounds naturally and became a model and actress. She has been on the cover of Woman's World Magazine and in countless other magazines, a guest on the Sherri Shepherd Show - Fit Over 50 segment, commercials, a movie and so much more.   Guest links:  Instagram / Threads: https://www.instagram.com/pszalay01/  Website: pauletteinspires.com Youtube: Sherri Show Fit Over 50 Segment - https://www.youtube.com/watch?v=S7E0gCKn-JM Today.com: https://www.today.com/health/diet-fitness/woman-loses-130-lbs-post-menopause-strength-training-low-carb-diet-rcna237318   Follow maddy's dating page here: https://www.instagram.com/its.maddymartinez?igsh=MXNvODZkNndlem5haA%3D%3D&utm_source=qr    To apply for Ali's Hot Mom Scholarship go here: https://forms.gle/mLBpP2n6Fu1Bs2Jv8  Find Ali here on  instagram:https://www.instagram.com/aliwagnercoaching/     Maddy's favorite redlight here and save: https://tinyurl.com/kindahot-hooga  Maddy's favorite Matcha brand:  https://tinyurl.com/kindahot-matcha  Maddy's favorite makeup: https://tinyurl.com/kindahot-subtlbeauty    Make sure to subscribe so you don't miss an episode and send us your health / relationship / life / just need advice on, submit your questions here: https://bit.ly/KHKH-ask-my-question   Find us on all streaming platforms here, including the full video experience on our YouTube channel

Host: Priya Vakharia, MD Guest: Andrew Moshfeghi, MD The SOL-1 Phase 3 superiority trial compared the efficacy and safety of the investigational product OTX-TKI (axitinib intravitreal hydrogel) with aflibercept 2 mg. The primary endpoint was proportion of subjects who maintained visual acuity, defined as

Seeing flashing lights, zigzags, blind spots, or visual disturbances before a migraine?In this episode of the Headache Doctor Podcast, Dr. Taves is joined by Novera headache specialist Dr. Kristen Bellasaro to break down ocular migraines, retinal migraines, and migraine with aura.They explain the differences between these diagnoses, why visual symptoms can be so alarming, and how the traditional medical model often focuses on symptom management rather than identifying the root cause.You'll learn:What an ocular migraine actually isThe difference between retinal migraine and migraine with auraWhy some migraines cause visual disturbances without head painWhat cortical spreading depression means—and why it may not explain the root causeHow neck dysfunction can contribute to visual symptoms and migraine presentationsWhy these symptoms are often treatable, even when imaging is normalIf visual symptoms, flashing lights, blind spots, or aura have left you feeling confused or worried, this episode will help you better understand what may actually be happening.

In this episode, cornea experts Dr. Keith Baratz and Dr. Elisabeth Cohen discuss the Herpes Zoster Eye Disease study. Tune in to appreciate how long term Valacyclovir minimizes the symptoms and sequelae of this challenging condition.    Subscribe to the podcast:  https://MayoClinicOphthalmology.podbean.com   Follow and reach out to us on X and IG: @mayocliniceye 

What if diagnosing PTSD, anxiety, and depression could be as objective as a blood test — done in 10 minutes on your phone?That's the vision behind Sensei, a company using AI and ocular biometrics to bring measurable, objective diagnostics to mental health. In this episode, host Deborah Westphal sits down with David Zakariaie, founder and CEO of Sensei, to talk about the science of the eye, a $2M technology problem solved with a commercial camera, and why fixing mental health starts with fixing measurement.Key TakeawaysMental health's biggest crisis isn't just a shortage of care — it's a measurement problem. Major depression, the most commonly diagnosed mental health condition in the U.S., is misdiagnosed approximately 65% of the time. PTSD, bipolar, and schizophrenia are misdiagnosed between 84–92% of the time.Sensei's diagnostic app shows patients a series of ocular stimuli for roughly 10.5 minutes, captures their eyes' responses via a standard smartphone camera, and outputs a binary diagnosis plus a severity score.The platform measures approximately 45 individual metrics across three categories: traditional ocular metrics (pupil size, blinks, saccades, gaze), iris dilator and sphincter dynamics (mapping sympathetic vs. parasympathetic nervous system activity), and heart rate and heart rate variability from facial video.Sensei is currently in Phase 3 clinical trials for a PTSD diagnostic, with an FDA submission planned for late 2025 and approval expected in 2027.About 16,000 people participated in pre-trial studies; the full dataset at submission is expected to reach approximately 30,000.The go-to-market strategy focuses on telehealth platform integration — partnering with companies like Spring Health, Talkspace, and BetterHelp to embed the diagnostic tool directly into existing care delivery workflows.Future expansion targets schizophrenia, bipolar disorder, and ADHD, with longer-term interest in neurodegenerative conditions like Alzheimer's and dementia.About David ZachariaDavid Zakariaie is the founder and CEO of Sensei, a mental health diagnostics company building the first FDA-regulatory-grade platform for diagnosing and monitoring PTSD, anxiety, and depression using AI-powered ocular biometrics. His path began at 15, when he attended Google I/O, received an early pair of Google Glass, and became fascinated with the scientific potential of the human eye. He left high school after 10th grade, taught himself to code, and launched the company in 2015.Resources & Links MentionedSensei: sensei.health (verify current URL)Mental Health Study (Phase 3 Trial Sign-Up): mentalhealthstudy.orgKaren Toffler Charitable Trust: tofflertrust.org (verify current URL)Parea Therapeutics (digital therapeutics reference)The CAPS-5 (Clinician-Administered PTSD Scale)The PCL-5 (PTSD Checklist for DSM-5)If You Enjoyed This EpisodeSubscribe to Research Renaissance wherever you listen to podcasts. If this conversation sparked something for you, share it with someone in healthcare, mental health advocacy, or neuroscience — this is the kind of work that needs more eyeballs on it.To learn more about the breakthroughs discussed in this episode and to support ongoing research, visit our website at tofflertrust.org. Technical Podcast Support by Jon Keur at Wayfare Recording Co.

O StrabCast e o SBOPCast se uniram para trazer conteúdos que vão além do que tivemos no 8° CBOPE!Neste episódio temos uma conversa muito enriquecedora com um dos nossos palestrantes internacionais que compareceu a 8° edição do CBOPE: Dr Eduardo Silva. Neste episódio conversamos sobre particularidades de doenças genéticas, perguntas e exames importantes para enriquecer sua pratica clínica.Material de Apoio:OMIM: Home - OMIM - (OMIM.ORG)GeneReviews: GeneReviews® - NCBI Bookshelf

O SBOPCast e o StrabCast se uniram para trazer conteúdos que vão além do que tivemos no 8° CBOPE!Neste episódio temos uma conversa muito enriquecedora com um dos nossos palestrantes internacionais que compareceu a 8° edição do CBOPE: Dr Eduardo Silva. Neste episódio conversamos sobre particularidades de doenças genéticas, perguntas e exames importantes para enriquecer sua pratica clínica.Material de Apoio:OMIM: Home - OMIM - (OMIM.ORG)GeneReviews: GeneReviews® - NCBI Bookshelf

Too busy to read the Lens? Listen to our weekly summary here! In this week's episode, we discuss:Ocular point-of-care ultrasound performed by emergency department physicians does not significantly reduce the number of ophthalmology consults for eye-related chief complaints.Routine glaucoma follow-up appointments may be delayed up to 60 days among patients with mild, stable disease. Those with moderate or severe disease may have greater odds of progression. Both the SII and INFLA-scores for systemic inflammation demonstrated significant, dose-dependent relationships with increased incidence of cataract formation, POAG, AMD, and DR, and were associated with retinal thinning on OCT.Intravitreal injections of KIO-301, a photoswitch molecule designed to make surviving retinal ganglion cells responsive to light in retinitis pigmentosa, demonstrate a favorable safety profile and early signs of functional vision improvement regardless of underlying gene mutation in the ABACUS-1 trial. 

Podcast host Cecelia Koetting, OD, FAAO, Dipl ABO, talks with ODs who contributed to MOD's recent aesthetics issue. Haley Perry, OD, discusses the optometrist as a salesperson and how to bridge the gap between doing what is best for the patient (and the practice) versus allowing insurance to dictate treatment. Kianna Swanson, OD, then chats about the ocular side effects of cancer medications and the importance of involving these patients in therapy decisions that prioritize maintaining and managing their comfort while on systemic medication.

O Afya News detalha as mudanças da Anvisa no Sistema Nacional de Controle de Receituários ampliando a digitalização e a rastreabilidade na prescrição de medicamentos controlados. Analisamos um relato do New England Journal of Medicine sobre a associação rara entre o uso do análogo de GLP 1 dulaglutida e o desenvolvimento de hiperplasia linfoide coroidiana bilateral. O episódio também destaca a inauguração do primeiro centro âncora de inovação em saúde do Brasil em Campinas voltado à produção de tecnologias e radiofármacos para o SUS. Afya News. Informação médica confiável e atualizada no seu tempo.Fontes do episódio aqui:https://portal.afya.com.br/podcasts/afya-news/22-05-2026

O Afya News destaca a declaração de Emergência de Saúde Pública de Importância Internacional pela OMS devido ao surto de Ebola pelo vírus Bundibugyo na África. Analisamos os resultados positivos do ensaio clínico de fase 3 com o elegrobart, um anticorpo monoclonal contra o receptor IGF 1R que traz melhorias significativas e reduz a necessidade de intervenções cirúrgicas na doença ocular da tireoide. O episódio aborda também novos estudos que demonstram que modelos avançados de inteligência artificial superaram médicos no diagnóstico de casos clínicos complexos, atuando como ferramenta estratégica para segundas opiniões.Afya News. Informação médica confiável e atualizada no seu tempo.Fontes do episódio aqui:https://portal.afya.com.br/podcasts/afya-news/18-05-2026

In this episode, I'm sharing a very real, very personal story about my daughter and what led me to take her to a developmental optometrist. As both a COTA and a mom, I always tell families “when in doubt, rule it out,” and this was one of those moments where I had to take my own advice.I walk through what I started noticing at home, from how she was positioning her head while writing, to her difficulty with attention during fine motor tasks, to hesitations with sports and play. At first, it was easy to brush some of it off as personality or age, but the patterns kept showing up.I share what our appointment actually looked like, what they were assessing, and the moment that really clicked for me when the doctor showed me what she might be seeing on a daily basis. It was one of those experiences where everything suddenly made more sense.I also talk about the difference between visual acuity and how the eyes actually function together. Just because a child can “see” doesn't mean their visual system is working efficiently. That was a big takeaway for me and something I think more families need to understand.This episode is really about awareness. Ocular motor skills, accommodation, and visual processing play such a huge role in things like attention, behavior, reading, and overall development, and they're often overlooked or mistaken for something else.I also share how to know who to go to if you're noticing similar concerns, what a developmental optometrist actually does, and why this can be such an important piece of the puzzle.This is just the beginning of our journey, and I'll continue to share updates as we learn more, especially if we move into vision therapy.Thanks for listening

Ocular aesthetics and dry eye are redefining optometry by shifting practices from product-based care to high-value services. Learn how to increase revenue per patient by 2–5x and unlock $20K–$100K+ per month in scalable growth.

Marc Bloomenstein, OD, FAAO, talks with Gina Wesley, OD, MS, FAAO, who owns a private practice in Medina, Minnesota. Dr. Wesley cold-started her clinic almost 20 years ago with an initial focus on contact lenses that shifted to dry eye management. She notes that dry eye treatment works in tandem with ocular appearance improvement—a win-win for patients. In this episode, she covers ocular aesthetic treatments ranging from dynamic muscle stimulation and radiofrequency to intense pulsed light and low-level light therapy, emphasizing the importance of proper lid hygiene and habits.

CME credits: 1.00 Valid until: 20-04-2027 Claim your CME credit at https://reachmd.com/programs/cme/beyond-iop-integrating-ocular-surface-resilience-into-glaucoma-management/49097/ Glaucoma care is shifting from a narrow focus on pressure targets to a broader, patient-centered approach that balances durable intraocular pressure (IOP) control with preservation of the ocular surface, comfort, and real-world adherence. But, daily practice often still defaults to drop-heavy regimens that can erode the very ocular surface on which long-term success depends. The chronic use of preserved topical medications can compromise the cornea and conjunctiva, perpetuating ocular surface disease (OSD) and ocular surface inflammation (OSI). These conditions not only degrade comfort and quality of life but also undermine adherence, accelerate treatment failure, and reduce the success rates of both medical and surgical interventions. Recent expert consensus underscores that every glaucoma patient should be screened for OSD/OSI, yet implementation remains inconsistent in daily practice. Contemporary perspectives and data support a shift toward ocular surface-sparing strategies, including preservative-free options, earlier laser strategies, and newer tear-restorative, anti-inflammatory, and neuromodulatory therapeutic options when OSD does occur.=

  This episode of WarDocs features Air Force Lieutenant Colonel, Dr. Charisma Evangelista, the Air Force's leading voice on refractive surgery and an expert in ocular trauma. The conversation begins with her upbringing in the Philippines and her unique path to military medicine, driven by a desire for service and the supportive, collaborative culture she found at the Uniformed Services University. Dr. Evangelista explains her transition from a prospective general surgeon to an ophthalmologist, highlighting the precision of microscopic surgery and the profound impact of sight restoration. She provides a detailed look at the "shield and ship" protocol for managing ruptured globes in combat environments, emphasizing the critical importance of preventing further injury at the point of care.    Dr. Evangelista also shares her experiences as the sole ophthalmologist deployed to Bagram, Afghanistan, where she managed severe, multi-system trauma cases while navigating limited resources. A pivotal moment in the interview occurs when she describes her own experience as a patient; she suffered a retinal detachment while performing surgery, an event that deepened her empathy for those facing vision loss and shaped her leadership style. Currently serving as the Refractive Surgery Consultant to the Air Force Surgeon General, she discusses the technological advancements in corneal collagen cross-linking and refractive standards that maintain pilot and warfighter readiness.    The episode concludes with her leadership philosophy of trust, empathy, and perseverance, alongside her advice for the next generation of military physicians. This comprehensive discussion highlights the technical expertise, emotional resilience, and deep compassion required to protect the vision of the American warfighter, offering listeners an inspiring look at the intersection of high-stakes surgery and humanitarian service. Chapters   (00:00-01:11) Introduction of Lt Col Charisma Evangelista, MD (01:12-05:13) Foundations in Medicine and the Choice of Ophthalmology (05:14-09:32) Specialized Training and Combat Deployment to Afghanistan (09:33-17:00) Ocular Trauma Protocols and Innovations in Refractive Surgery (17:01-22:35) Personal Resilience as a Patient and Leadership Philosophy (22:36-27:10) Advice for Future Medics and Defining a Military Hero Chapter Summaries   (00:00-01:11) Introduction of Lt Col Charisma Evangelista, MD: The episode opens with a tribute to the delicate nature of eye surgery in combat. Host Dr. Doug Soderdahl introduces Dr. Charisma Evangelista as a deeply compassionate healer and a leading expert in military ophthalmology and refractive surgery standards. (01:12-05:13) Foundations in Medicine and the Choice of Ophthalmology: Dr. Evangelista shares her journey from a small town in the Philippines to the Uniformed Services University, highlighting the family-oriented culture of military medical training. She discusses her transition from general surgery to ophthalmology, sparked by a love for microscopic precision and the collaborative nature of the specialty. (05:14-09:32) Specialized Training and Combat Deployment to Afghanistan: The discussion follows Dr. Evangelista through her prestigious civilian fellowship and her subsequent deployment to Bagram Airfield. She details the challenges of serving as the sole ophthalmologist in a combat theater, managing severe ocular trauma and multi-system injuries with limited resources. (09:33-17:00) Ocular Trauma Protocols and Innovations in Refractive Surgery: This section focuses on the "shield and ship" protocol for point-of-injury care and the rewarding outcomes of sight-restoring surgeries. Dr. Evangelista also explains her role as a consultant for the Air Force Surgeon General, detailing how advancements like corneal collagen cross-linking keep service members mission-ready. (17:01-22:35) Personal Resilience as a Patient and Leadership Philosophy: Dr. Evangelista provides a moving account of her own retinal detachment and the traumatic recovery process that followed. She explains how being a patient informed her leadership at the Department of Defense's largest eye center, prioritizing trust, empathy, and perseverance. (22:36-27:10) Advice for Future Medics and Defining a Military Hero: In the final segment, Dr. Evangelista offers encouragement to pre-med and medical students, emphasizing the unique opportunities for growth in military medicine. She reflects on her "Hero of Military Medicine" recognition and her desire to leave a legacy of inspiration and compassionate service. Take Home Messages Protecting the Ruptured Globe: In cases of severe ocular trauma, the most critical step for non-specialists is the "shield and ship" protocol, which involves placing a hard, protective shield over the eye without applying any pressure to the globe. Preventing additional injury at the point of care is essential for giving specialists the best chance to restore a service member's vision. Refractive Surgery as a Readiness Multiplier: Laser vision correction and specialized treatments for conditions like keratoconus are more than elective procedures; they are essential for warfighter readiness. By reducing dependence on eyeglasses and stabilizing corneal conditions, military ophthalmologists ensure that pilots and ground troops can perform their duties with maximum agility and precision. Empathy through the Patient Experience: True compassion in medicine often stems from understanding the fear and uncertainty of the patient. Experiencing a serious medical crisis personally can transform a surgeon's perspective, allowing them to lead with greater empathy and build deeper trust with those under their care. The Collaborative Power of Military Medicine: The military medical system thrives on a culture that prioritizes collective success over individual competition. This foundation of unit cohesion ensures that physicians work together across specialties to provide the highest standard of care in both domestic hospitals and austere combat environments. Persistence in the Face of Adversity: Success in high-stakes fields like ophthalmology requires the ability to persevere through personal health crises, professional challenges, and the rigors of deployment. Growth and innovation often occur as a direct result of these struggles, making a leader more resilient and effective in their mission to serve.   Episode Keywords Military Medicine, Ophthalmology, Ocular Trauma, Eye Surgery, Refractive Surgery Standards, LASIK, PRK, K-LEX, Corneal Collagen Cross-linking, Keratoconus, Bagram Airfield, Combat Medic Training, Eye Injury Protocols, Shield and Ship, Retinal Detachment, Uniformed Services University, Air Force Surgeon General, Hero of Military Medicine, Surgical Leadership, Medical Humanitarian Missions, WarDocs Podcast, Dr. Charisma Evangelista, Sight Restoration, Combat Surgery, Military Healthcare. Hashtags #MilitaryMedicine, #Ophthalmology, #CombatSurgery, #EyeHealth, #WarDocs, #AirForceMedicine, #RefractiveSurgery, #VeteransHealth   Honoring the Legacy and Preserving the History of Military Medicine The WarDocs Mission is to honor the legacy, preserve the oral history, and showcase career opportunities, unique expeditionary experiences, and achievements of Military Medicine. We foster patriotism and pride in Who we are, What we do, and, most importantly, How we serve Our Patients, the DoD, and Our Nation.   Find out more and join Team WarDocs at https://www.wardocspodcast.com/ Check our list of previous guest episodes at https://www.wardocspodcast.com/our-guests Subscribe and Like our Videos on our YouTube Channel: https://www.youtube.com/@wardocspodcast Listen to the “What We Are For” Episode 47. https://bit.ly/3r87Afm   WarDocs- The Military Medicine Podcast is a Non-Profit, Tax-exempt-501(c)(3) Veteran Run Organization run by volunteers. All donations are tax-deductible and go to honoring and preserving the history, experiences, successes, and lessons learned in Military Medicine. A tax receipt will be sent to you. WARDOCS documents the experiences, contributions, and innovations of all military medicine Services, ranks, and Corps who are affectionately called "Docs" as a sign of respect, trust, and confidence on and off the battlefield,demonstrating dedication to the medical care of fellow comrades in arms.     Follow Us on Social Media Twitter: @wardocspodcast Facebook: WarDocs Podcast Instagram: @wardocspodcast LinkedIn: WarDocs-The Military Medicine Podcast YouTube Channel: https://www.youtube.com/@wardocspodcast

In a new episode of the pharmaphorum podcast, web editor Nicole Raleigh spoke with Lance Baldo, CEO of Beacon Therapeutics, a clinical-stage biotechnology company harnessing the transformative power of gene therapy to deliver meaningful outcomes for severe ocular diseases. Baldo discusses the ocular disease landscape, as well as Beacon's work targeting X-linked retinitis pigmentosa (XLRP) and geographic atrophy (GA), and what the future could look like in terms of innovation in this field. You can listen to episode 253 of the pharmaphorum podcast in the player below, download the episode to your computer, or find it – and subscribe to the rest of the series – on Apple Podcasts, Spotify, Overcast, Pocket Casts, Podbean, and pretty much wherever else you download your other podcasts from.

Erick Rivera Grana, MD, meets with host Ogul Uner, MD, to review a case of a 34-year-old woman who experienced blurred vision and mild discomfort in her right eye with an IOP of 38 mm Hg. The patient also presented with conjunctival injection and posterior synechiae. Dr. Rivera Grana describes his diagnostic approach to this case and explains the management of uveitic ocular hypertension and uveitic glaucoma.

Today, we're joined by Dr. Barbara Tylka, an optometrist at Mayo Clinic in Rochester and founder of our multidisciplinary Dry Eye Clinic. She specializes in advanced dry eye and ocular surface disease. Tune in to hear practical dry eye strategies to improve clinic efficiency and patient experience  Subscribe to the podcast:  https://MayoClinicOphthalmology.podbean.com   Follow and reach out to us on X and IG: @mayocliniceye 

 In this episode of the PA Insights Podcast, we welcome Noor Ali, DMSc, MPAS, PA-C, a Board Certified PA practicing in ocular oncology. Ali shares her journey into the field, discussing the challenges and rewards of working in such a specialized area. She emphasizes the importance of teamwork, mentorship, and continuous learning in her career. The conversation also delves into the day-to-day responsibilities, the role of PAs in subspecialty care, and the personal stories that have shaped Noor's professional path.

Learn the symptoms of retinal and ocular migraines, such as twinkling, shimmering, or flashing lights in the visual field, which are classic symptoms of both retinal and ocular migraines. ​Some differences include: retinal migraines typically affect only​ one eye and are more serious, while ocular migraines (migraine with aura) usually affect both eyes​ and involve zigzags or blind spots. For more episodes of Ageless Health® with Dr. Tom Roselle, DC please visit: https://www.drtomroselle.com/ageless-health-podcast/ #AgelessHealth @DrTomRoselleDC @WMALDC @RoselleCare #AppliedKinesiology #RoselleCenterForHealing #HolisticHealth #IntegrativeHealth #FunctionalMedicine #HealthEducation #chronicheadaches #migraines #botox #intermittentfasting #retinalmigraine #ocularmigraine

Ocular melanoma is one of the rarest forms of cancer — and because of that, it's often misunderstood.   In Episode 4 of My 15 Years, Melody talks about some of the most common misconceptions surrounding ocular melanoma, including funding challenges that come with such a rare diagnosis.   She also reflects on what advocacy looked like in the early days of her journey, when awareness of ocular melanoma was limited and resources for patients were far fewer than they are today. Melody shares how those early experiences helped shape her commitment to raising awareness and supporting the ocular melanoma community.   This episode sheds light on the realities of living with a rare cancer and the importance of advocacy, education, and community.

Despertar Podcast — Episodio: Ver sin los ojos ¿Es posible ver sin los ojos? ¿O estamos olvidando algo que siempre estuvo dentro de nosotros? En este episodio de Despertar Podcast exploramos una conversación profunda sobre intuición, crianza consciente, visión extra ocular y el verdadero trabajo de los padres. Una familia que decidió escuchar su sentir. Hablamos sobre Intuición infantil Padres conscientes Crianza emocional Niños altamente sensibles Visión mental Campo familiar Anclajes emocionales Cómo creer para ver Si este episodio te movió algo por dentro, te invitamos a vivir la experiencia: un seminario o retiro presencial.

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into a series of breakthroughs and strategic maneuvers that are reshaping the landscape of this dynamic industry.Roche is making waves with its antibody Gazyva, initially recognized for cancer treatment. The company has successfully ventured into autoimmune diseases, targeting kidney conditions. Recent phase 3 trials have reinforced Gazyva's efficacy in treating immune-mediated kidney diseases, building on its prior approval for lupus nephritis. This marks a potential paradigm shift from oncology to autoimmune therapy applications, offering a promising new avenue for treating complex kidney disorders. Such advancements underscore the power of immune modulation in addressing severe health conditions.Turning to oncology, Eli Lilly is expanding the use of its cancer drug, Retevmo. Originally approved for specific lung and thyroid cancers with rare biomarkers, Lilly is now exploring its use in the adjuvant setting for non-small cell lung cancer. This effort reflects a broader trend in oncology: companies are increasingly looking to extend the application of targeted therapies beyond their initial indications. This expansion could significantly enhance treatment options and improve patient outcomes.In ophthalmology, Ocular Therapeutix is preparing for an FDA filing following positive phase 3 results for its wet age-related macular degeneration treatment. Their candidate, AXPAXLI, showed superior efficacy compared to Regeneron's Eylea in head-to-head trials. Despite investor skepticism, Ocular remains confident in its product's potential to impact retinal disease management positively. The competitive landscape in ophthalmology is fierce, and innovative treatments with substantial clinical benefits over existing therapies can redefine standards of care.Eli Lilly is also strategically stockpiling Orforglipron, its oral GLP-1 candidate, in anticipation of FDA approval for obesity treatment. This proactive measure aims to prevent supply chain issues seen during previous GLP-1 launches. It reflects an industry-wide focus on ensuring product availability at launch to meet growing market demand effectively.On the regulatory front, there are significant shifts as well. The Trump administration's renewed pilot of 340B rebates aims to optimize drug pricing frameworks. Novartis has secured a long-term supply agreement with Niowave for Actinium-225 (Ac-225), crucial for developing targeted cancer therapies. This highlights the sustained demand for radiopharmaceutical isotopes as part of precision medicine initiatives.Biopharma funding is expected to recover steadily by 2026, albeit with a cautious approach favoring de-risked assets over broader platform technologies. Venture capitalists prefer predictable returns amidst an evolving market landscape.Now, let's turn to Japan, where Innovacell is planning a $92 million IPO on the Tokyo Stock Exchange. This move signals a renewed interest in biotech within the region after a long drought in IPOs. Financial strategies like these are vital for advancing cell therapies that hold promise for treating conditions once deemed challenging.Gilead Sciences has acquired synthetic lethal therapy from Genhouse Bio through a $1.5 billion deal, further underscoring the growing interest in synthetic lethality as a novel cancer treatment approach. This strategy focuses on targeting tumors while sparing normal cells, offering more effective therapies with fewer side effects.In mental health innovations, Compass Pathways has reported positive results from its pivotal trial using psilocybin for treatment-resistant depression. The success of this phase 3 trial highlights the potential role of psychedelics in psychiatric care and could revolutionize mental health treatments by providing new options Support the show

Ocular herpes and shingles are often misunderstood, misdiagnosed, and treated too late. In this episode, we break down herpes simplex virus (HSV) and herpes zoster affecting the eye, focusing on real world clinical insights that go far beyond textbook explanations. Whether you are an eye care professional, healthcare provider, medical student, or someone seeking reliable medical education, this conversation offers clear, practical, and evidence based insights into ocular viral disease.

In this episode of the Tick Boot Camp Podcast, Matt Sabatello sits down with Yuri Kim, the lead clinical research nurse for MIT's MAESTRO study, described as one of the largest studies in MIT history focused on Lyme disease and Infection-Associated Chronic Illnesses (IACI). Yuri explains how MAESTRO is collecting deep symptom histories and objective measurements—from eye tracking and EEG/P300 auditory testing to NASA Lean dysautonomia testing, capillaroscopy, and multi-sample biological collection—to identify patterns that validate patient experiences and accelerate real-world clinical understanding. Yuri's story is equally compelling: she began as an ER nurse in a Level 1 trauma center, transitioned into research nursing (including neurodegenerative and traumatic brain injury work), moved to South Korea during the pandemic, and ultimately joined MIT after a conversation with Dr. Mikki Tal changed the course of her career. Throughout the conversation, Yuri shares what she's learned from MAESTRO participants: a community often exhausted and dismissed, yet profoundly motivated to help others and drive scientific progress forward. Key Takeaways (Fast Scan) MAESTRO is nearing ~200 participants enrolled, with the chronic Lyme cohort full and enrollment closing soon. The study aims to objectively measure symptoms often dismissed as “anxiety” or “depression,” especially brain fog and dysautonomia. MAESTRO uses multiple cognitive and neurologic measures, including RightEye eye tracking, EEG + P300 auditory “oddball” testing, and remote cognitive battery tests. The team added capillaroscopy (nailfold and toe microvascular imaging) to explore vascular patterns and hemorrhages in chronic illness cohorts. Dysautonomia testing includes NASA Lean Test plus an earpiece device to estimate proxy cerebral blood flow, sometimes showing abnormalities even when vitals look “normal.” Extensive biological sampling (oral, blood, vaginal/rectal) supports proteomics/immune profiling and deeper molecular analysis. Yuri emphasizes: patients' willingness to participate—despite severe symptoms—is the engine of progress and future change. Detailed Chapter-by-Chapter Show Notes 1) Meet Yuri Kim: The Human Side of Cutting-Edge Lyme Research Matt introduces Yuri as the clinical research nurse leading day-to-day operations of MIT's MAESTRO study—positioning her as a rare bridge between lab science, clinicians, and patients. Yuri shares that the study is approaching enrollment completion and that the team is eager to analyze a large dataset to “speak up” for participants who have suffered without clear explanations. Highlights: MAESTRO is one of MIT's largest studies, with enrollment nearing completion. The mission is to transform patient suffering into measurable signals, data, and insight. 2) Yuri's Background: Pharma, ER Nursing, Research, and Why This Work Became Personal Yuri explains her path: early work as a medical information specialist in pharma (including literature searches and clinician guidance, often involving off-label questions), then an intense period as a Level 1 ER nurse where she witnessed both acute crises and chronic illness desperation. Key insight:Yuri notes that in pharma and ER settings, she repeatedly saw the same reality—patients searching for answers, clinicians constrained by time, and chronic illness voices falling through the cracks. 3) From the ER to Neuro Research: Brain Inflammation, TBI, and the Gap in Chronic Illness Care Yuri left ER work largely due to the physical toll of night shifts and moved into academic research at Boston University. She worked on complex studies involving Alzheimer's, amyloidosis, and traumatic brain injury. Matt asks whether Lyme came up in those neuro settings. Yuri says no—but now she views neurodegenerative symptoms differently and believes clinicians should consider underlying root causes, including infection. Listener connection:This segment reinforces how often Lyme-related cognitive decline can be misinterpreted or missed when viewed through siloed specialties. 4) Lyme Awareness Outside the U.S.: South Korea, Tick-Borne Illness, and Global Blind Spots During the pandemic, Yuri relocated to South Korea. She shares that Lyme isn't commonly discussed there, though other tick-borne illnesses exist. Yuri underscores a global concern: agricultural and rural communities face tick exposure without awareness of the chronic implications. 5) How Yuri Joined Dr. Mikki Tal and MAESTRO (And Why She Changed Her Mind) One of the most memorable segments: Yuri reveals she had already accepted another MIT nursing role—but after speaking with Dr. Tal, she pivoted immediately, calling it the best career decision she's ever made. Why it matters: It shows how MAESTRO is not just a study; it's a mission-driven effort that attracts top clinical talent. 6) Day One at MAESTRO: Meeting the Severely Ill and the Community's Unmatched Generosity Yuri recounts a powerful early experience: meeting a participant who was bedbound and profoundly symptomatic, yet eager to contribute anything possible to help the community. Matt connects this to Tick Boot Camp's origin story: people with minimal energy still showed up to help others. The theme becomes clear—Lyme patients are often depleted but relentlessly generous. What MAESTRO Measures (The Four-Hour Visit Breakdown) 7) Brain Fog: Why MAESTRO Treats It as a Complex Phenomenon Yuri explains MAESTRO's approach: brain fog isn't one symptom. It can involve memory, processing speed, visual stimulation sensitivity, pain-triggered cognition changes, and motor response delays. Core idea: MAESTRO attempts to measure brain fog from multiple angles—visual processing, auditory processing, reaction time, and executive function. 8) RightEye Eye Tracking: Visual Stimulus + Reaction Time as Objective Signal Participants complete a structured set of ocular motor tasks (pursuit, saccades) and reaction-time games (shape recognition mapped to numbered inputs). Yuri notes many chronic illness participants struggle even with basic saccades, often aligning with reported visual disturbances. What MAESTRO is measuring: Ocular motor control Visual processing Decision speed Reaction time consistency 9) EEG + P300 “Oddball” Test: Auditory Processing Meets Motor Output Participants wear an EEG cap (19 regions) and listen to tones: common low-pitch and rare high-pitch. They must press the spacebar only for the rare tone. Yuri notes that even a 4-minute test can be exhausting for people with cognitive dysfunction, and participants often describe a frustrating “delay” between knowing what to do and physically doing it. Why this matters: This may help validate cognitive dysfunction even when standard office screening looks normal. 10) Remote Cognitive Battery Testing: Scaling Measurement Beyond MIT Participants complete executive function tests at home (memory, Stroop-like color-word matching, trail-making tasks). Yuri emphasizes why this matters: many patients can't travel, and symptoms vary dramatically by day, cycle, and crash patterns. Big future direction: Remote testing could expand access to bedbound patients and capture “good day vs bad day” variability. 11) Dysautonomia & POTS: NASA Lean Test + Proxy Cerebral Blood Flow Yuri details NASA Lean testing: supine rest, then standing/leaning while monitoring vitals and symptoms. The standout: sometimes vitals appear stable while patients feel intensely symptomatic—yet the cerebral blood flow proxy measurement fluctuates significantly. Clinical implication discussed: This approach could become a tool for identifying dysautonomia-related issues when standard vitals “look fine.” 12) Capillaroscopy: Nailfold + Toe Microvascular Imaging MAESTRO added capillaroscopy to examine microvascular patterns, including abnormal shapes and possible hemorrhages seen more frequently in chronic cohorts (as her clinical observations suggest). They also measure capillaries pre- and post-NASA Lean to explore whether symptomatic shifts correlate with microvascular changes. Why patients find it meaningful: They can visually see something measurable that aligns with how they feel. 13) Standard Neuro Screening Doesn't Capture Lyme Brain Fog Yuri shares a crucial point: participants often perform fine on standard screens like the Mini-Mental State Exam, suggesting that infection-associated cognitive dysfunction can be subtle, dynamic, and not detected by traditional tools—reinforcing the need for MAESTRO-style measurement. Biological Samples: “Measure Everything” (Head to Toe) 14) Multi-Sample Collection: Oral, Blood, Vaginal, Rectal Yuri explains the breadth of biological sampling, including saliva/oral samples (cotton chew + gum swab), multiple blood tubes, and sex-specific sampling to explore immune, hormonal, microbiome, and gynecologic dimensions. Why it's being done: To connect symptom clusters to molecular patterns and explore sex differences in chronic illness response. 15) Storage, Batch Effects, and What Happens After Enrollment Closes Samples are aliquoted and stored at -80°C until they can be processed/shipped in ways that minimize batch effects. The next phase is analysis and collaboration—including proteomics and immune signaling exploration. 16) Giving Back to Participants: The Challenge and the Intention Yuri acknowledges the “fine line” between research-only testing and clinically actionable reporting, but stresses MIT's intention to return what can be responsibly shared through certified partners—while being careful not to over-interpret research findings. Collaboration, Scaling, and What Comes Next 17) Collaboration Across Institutions: The Missing Platform Matt compares Lyme research needs to cybersecurity threat-sharing between banks: competitors collaborate because the threat is bigger than any one organization. Yuri agrees and highlights the need for secure data-sharing platforms—similar to large national efforts in other fields. 18) What's Next: Focus on Female Brain Fog, Hormones, and Remote Studies Yuri previews upcoming directions: Brain fog and hormone cycle relationships Differentiating infection-associated cognitive dysfunction vs menopause-related brain fog Remote/at-home measurement studies to reach more symptomatic and bedbound patients Potential collaborations with pediatric and neuroimmune experts Closing Message: Hope Without Hype Yuri's message to patients and families is simple and emotional: “Please don't give up.” She believes answers are coming because serious teams are working together—and because patients are driving the research forward with their participation.

This SEO-optimized clinical briefing is designed for the optometric community. It synthesizes the AOA Evidence-Based Optometry (EBO) Committee June 2025 clinical report with the professional insights of Dr. Andrew Morgenstern, Director of the AOA Clinical Resources Group, regarding the management of patients on GLP-1 receptor agonists.

Episode 3: Ocular Melanoma 101 & My Treatment Experience   Understanding a rare cancer can feel overwhelming — especially at the moment of diagnosis.   n Episode 3 of My 15 Years, Melody breaks down the basics of ocular melanoma (OM 101) in a clear, approachable way. She explains what ocular melanoma is, and how she felt as a newly diagnosed patients.   Melody also goes deeper into her personal treatment experience, sharing what plaque brachytherapy was like — from preparing for the procedure to living through treatment and recovery.   This episode is designed to help patients, caregivers, and loved ones better understand ocular melanoma, while grounding the information in real lived experience.   Rare Cancer. Resilient Hope. Revolutionary Research.

Sudden vision loss is not normal — and it's not something to "wait and see." If you've ever experienced a dark curtain, shadow, blur, or sudden vision change, this episode could be life-saving. In this episode of the Uncover Your Eyes podcast, Dr. Meenal Agarwal breaks down one of the most missed medical emergencies she sees in clinical practice: ocular stroke, a critical warning sign of serious vascular disease and future stroke risk. An ocular stroke is often the first red flag before a larger, more devastating neurological event. And yet, many people are told it's "just stress," "eye strain," or something that will pass.

A red, painful eye is not always allergies it can be ocular herpes, a serious infection that can permanently damage your vision if treated incorrectly. In Part 2, Dr. Mika Moy explains how herpes simplex virus (HSV) affects the eye, what herpes keratitis looks like, and why early symptoms are often missed. Learn how doctors identify the classic “dendrite” pattern on the cornea, why steroid eye drops can make the infection worse, and when antiviral treatment must start immediately.

A red eye is not always allergies or irritation it can be a sign of a serious eye infection. In this episode, we break down the real causes of red eye, including ocular herpes, chlamydia eye infections, and other conditions that are often misdiagnosed or ignored. Many of these infections can lead to permanent vision damage if they are treated too late or with the wrong eye drops. Learn how to recognize the warning signs that mean a red eye is an emergency, why “waiting it out” can be dangerous, and when common treatments can actually make things worse.

In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the Januray 2026 Emergency Medicine Practice article, Emergency Department Diagnosis and Management of Patients With SyphilisSyphilis cases have surged 42% in the US, making it critical for emergency physicians to recognize and treat this "great masquerader." In this episode, hosts Sam Ashoo and Dr. T.R. Eckler break down the January 2026 Emergency Medicine Practice article on syphilis diagnosis and management. They cover the rising prevalence in high-risk populations, the four clinical stages (primary, secondary, latent, and tertiary), special presentations like neurosyphilis and congenital syphilis, and practical diagnostic approaches. With a national penicillin shortage, they discuss alternative treatment options including doxycycline and post-exposure prophylaxis. The conversation also addresses the dark history of the Tuskegee Study and its lasting impact on medical ethics. Whether you're seeing more cases in your ED or want to sharpen your diagnostic skills, this episode provides actionable insights for frontline providers.Timestamps[0:00] Opening/Introduction[0:11] Host Welcome & Resources[0:50] Episode Introduction[1:30] Epidemiology & Rising Cases[4:30] Risk Factors & Screening[6:30] Pathophysiology & Transmission[9:30] Primary Syphilis[12:30] Secondary Syphilis[15:30] Tertiary & Latent Syphilis[18:30] Neurosyphilis[22:30] Congenital Syphilis[25:30] Ocular & Otic Syphilis[28:30] Differential Diagnosis & Pre-hospital Care[31:30] History & Physical Examination[34:30] Diagnostic Testing Overview[38:30] Testing Details & Titers[41:30] Treatment: Penicillin & Alternatives[43:30] ClosingSubscribers, take the CME test here.Emergency Medicine Residents, get your free subscription by writing resident@ebmedicine.net

In today's VETgirl online veterinary continuing education podcast, we discuss the latest on antiviral therapy for feline infectious peritonitis (FIP) with ocular involvement, based on a recent JVIM paper. Tune in to learn how antivirals may be reshaping treatment for ocular FIP, hear practical pearls to guide your management, set clear expectations with pet owners, and refresh how you approach FIP-related eye disease in everyday practice.

In today's VETgirl online veterinary continuing education podcast, we discuss the latest on antiviral therapy for feline infectious peritonitis (FIP) with ocular involvement, based on a recent JVIM paper. Tune in to learn how antivirals may be reshaping treatment for ocular FIP, hear practical pearls to guide your management, set clear expectations with pet owners, and refresh how you approach FIP-related eye disease in everyday practice.

What if simply *looking* at art could help regulate your nervous system, calm your mind, and restore emotional balance? In this deeply moving episode of HIListically Speaking, host Hilary Russo sits down with LeeAnn Heltzel, multidimensional artist, conscious explorer, and creator of MetaArt; frequency-infused abstract artwork designed as portals for ocular (eyes-open) meditation. They discuss the art form, the benefits, and the connection to Millions Meditating Alliance, the UN's World Meditation Day, and how you can join them for the healing.   MEDITATE WITH THE MILLIONS MEDITATING ALLIANCE (World Meditating Day - Dec 21) https://millionsmeditatingnow.com/   REGISTER & JOIN HILARY FOR THE UN WORLD MEDITATION DAY HAVENING HAPPY HOUR https://us02web.zoom.us/meeting/register/TH-dsgnrThKwm-kol4CjHQ   CONNECT WITH LEEANN https://www.leeannheltzel.com/ https://www.instagram.com/Leeannheltzel https://www.tiktok.com/@meta.artist   Use the code HUGITOUT20 for 20% off any MetaArt reproduction or commission. https://www.leeannheltzel.com/store   JOIN ME ON SUBSTACK - THE BRAIN CANDY BLUEPRINT! ⁣https://substack.com/@hilaryrusso ⁣ GET BRAIN CANDY & WAYS TO BE KIND TO YOUR MIND DELIVERED TO YOUR INBOX⁣ https://www.hilaryrusso.com/braincandy⁣ DISCOVER HAVENING TECHNIQUES TRAININGS & WORKSHOPS⁣ https://www.hilaryrusso.com/training⁣ ⁣ BOOK HILARY FOR YOUR NEXT EVENT OR ATTEND!⁣ https://www.hilaryrusso.com/events⁣ ⁣ CONNECT WITH HILARY⁣ https://www.linkedin.com/in/hilaryrusso⁣ https://www.instagram.com/hilaryrusso⁣ https://www.instagram.com/hilisticallyspeaking⁣ https://www.youtube.com/hilaryrusso⁣ https://www.hilaryrusso.com/podcast⁣ ⁣ MUSIC by Lipbone Redding⁣ https://www.lipbone.com⁣

Today's guest is Tessa Parry-Wingfield, global communications consultant, public speaker, and survivor of ocular melanoma, a very rare form of eye cancer that affects about 6 people per million annually. She has found purpose in her adversity and ironically "sees life clearly" despite her vision issues.We talk about learning to live with a prosthetic eye and monocular vision, the challenges of rare cancers, eye and vision health (see your eye doctor regularly), finding purpose and clarity post diagnosis, and so much more!Resources:Tessa's Website: Tessa Parry-Wingfield | Speaker + Storyteller | Seeing life clearly |Tessa's Instagram: https://www.instagram.com/seeing_life_clearly/Tessa's LinkedIn: Tessa Parry-Wingfield | LinkedInFollow:Follow me: https://www.instagram.com/melissagrosboll/My website: https://melissagrosboll.comEmail me: drmelissagrosboll@gmail.com

“Olivia Colman, calm down.”This week's scariest movie is... Hot Fuzz. This film has everything: Ocular patdowns. A loose swan. And a the most charming bond to walk the earth. If you love buddy-cop bromance, murder-murder-murder chants, and suggestive headlines, this episode's for you!Please Subscribe, Rate, and Review The Horror Virgin to help more people discover our community.What did you think of our episode on Hot Fuzz? Tell us on social media @HorrorVirgin (Facebook/Instagram), @HorrorVirginPod (Twitter).Up Next: Krampus (2015)See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In the November 2025 episode of Critical Decisions in Emergency Medicine, Drs. Danya Khoujah and Wendy Chang discuss acute radiation sickness and ocular foreign bodies. As always, you'll also hear about the hot topics covered in the regular features, including recurrent palpitations in a middle-aged man in The Critical ECG, primary adrenal insufficiency in Clinical Pediatrics, Lisfranc injury in Critical Cases in Orthopedics and Trauma, active external rewarming of hypothermic patients in The Critical Procedure, managing patients with acute visual loss in The LLSA Literature Review, abdominal pain in a child after a fall in The Critical Image, acetylcysteine for acetaminophen toxicity in The Drug Box, and carbon monoxide toxicity in The Tox Box.

Welcome to Session 1 of the Eye Believe Survivorship Seminar 2025! This 8:00 AM session features renowned ocular oncologist Dr. MATERIN (Duke Health) as he presents “Yesterday, Today & Tomorrow in Ocular Melanoma.” In this powerful opening session, Dr. Materin walks attendees through:

In this episode, we sit down with Vanessa Tompkins, wife and caregiver to Mike, who has been battling Stage 4 metastasized ocular melanoma. Over the past five years, Vanessa has supported Mike through weekly immunotherapy, four major surgeries—including the removal of his left eye, liver surgery, triple hernia repair, and open-heart surgery—and countless challenges along the way.A registered nurse, former hospice nurse, and current Sexual Assault Forensic Examiner, Vanessa brings professional expertise, personal experience, and unwavering compassion to her role as a caregiver. She is also a mother of three, grandmother of four, and devoted owner of her golden lab, Romeo. Guided by her motto, “One day at a time,” Vanessa shares insights into the realities of caregiving, the emotional resilience required, and the lessons learned in supporting a loved one through a complex and ongoing cancer journey.Tune in to hear her story, practical tips, and heartfelt reflections on the challenges and rewards of being a caregiver.

Contributor: Taylor Lynch, MD Educational Pearls: What is orbital compartment syndrome, and how is it assessed in the emergency room? Orbital compartment syndrome (OCS) is an emergent ophthalmic condition in which intraorbital pressure in the orbital compartment rises dramatically, compromising perfusion of the optic nerve and retina, leading to risk of irreversible vision loss. OCS occurs in the context of traumatic lesions with retrobulbar hemorrhage. Intraocular pressures (IOP) are measured via tonometry as a surrogate for intraorbital pressures, with emergent pathology being present when IOP exceeds 30-40 mmHg (normal being around 20 mmHg). What might be some physical exam findings beyond increased IOP for orbital compartment syndrome? Proptosis (physical outward protrusion of eye) with resistance to being pushed posterior. Afferent pupillary defect (when the non-impacted eye has light shown into it, the impacted eye will have pupillary constriction, and when light is removed it will begin to dilate, but when light is shown into the impacted eye, it will not constrict and continue to dilate). Generalized complaints of vision loss or an inability to move the eye. What is the treatment for orbital compartment syndrome? Lateral canthotomy must be performed immediately upon clinical suspicion as permanent vision loss can occur within minutes to hours.  Lateral canthotomy Step-by Step: Ideally have the patient sedated or highly cooperative. Numb and vasoconstrict the surrounding eye/orbital skin tissue with lidocaine and epinephrine. Take hemostats and clamp the interior and exterior eyelid at the lateral canthus at a 90º angle towards the orbital rim for 30-60 seconds to further devascularize the region. Take iris scissors and cut laterally to the orbital bone/rim to reveal the lateral lanthal tendon. Cut the inferior crus of the lateral lanthal tendon as this will provide the most significant reduction in IOP. Reassess IOP during each step of the procedure to measure procedure efficacy. If no pressure reduction is noted with inferior cantholysis, cutting the superior crus of the lateral canthal tendon may be required to further allow the eye to bulge out and reduce intraorbital pressure. Big takeaways? Ocular compartment syndrome is a rare but emergent vision threatening condition that requires immediate lateral canthotomy to reduce intraocular and intraorbital pressures. Lateral canthotomy done within 30-60 minutes of symptom development can save the patient from permanent vision loss. References: Mohammadi F, Rashan A, Psaltis A, et al. Intraocular Pressure Changes in Emergent Surgical Decompression of Orbital Compartment Syndrome. JAMA Otolaryngol Head Neck Surg. 2015;141(6):562-565. doi:10.1001/jamaoto.2015.0524 Haubner F, Jägle H, Nunes DP, et al. Orbital compartment: effects of emergent canthotomy and cantholysis. Eur Arch Otorhinolaryngol. 2015;272(2):479-483. doi:10.1007/s00405-014-3238-5 Bailey LA, van Brummen AJ, Ghergherehchi LM, Chuang AZ, Richani K, Phillips ME. Visual Outcomes of Patients With Retrobulbar Hemorrhage Undergoing Lateral Canthotomy and Cantholysis. Ophthalmic Plast Reconstr Surg. 2019;35(6):586-589. doi:10.1097/IOP.0000000000001401 Summarized by Dan Orbidan, OMS2 | Edited by Dan Orbidan and Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/

In this episode, we interview Danny Powell, an ocular melanoma (OM) patient whose tumor was identified early thanks to his eye doctor noticing a change and acting quickly. Danny explains his diagnosis, his treatment with brachytherapy, and how he later discovered that his grandmother also had OM—an extremely rare family connection. This prompted genetic testing, which revealed that Danny carries a BAP1 gene mutation. He discusses what that means for his ongoing care, his decision to join a clinical study, and the importance of regular surveillance scans. Whether you're an OM patient, caregiver, or medical professional, this episode provides practical insight into early detection, genetic risk factors, and patient involvement in research.

¿Te pican, se irritan o te lloran demasiado los ojos?

In this call to action, Drs. Robert Mazzoli, Stuart Seiff, and Jon Perlstein share the scope of issues surrounding ophthalmic trauma care in the United States and a roadmap for improving it, including how we can translate experiences from the military into our own set of Damage Control Ophthalmology (DCO) guidelines. Referenced article: A Call to Action and Roadmap for Improving Emergency Treatment of Ophthalmic Trauma in the United States For all episodes or to claim CME credit for selected episodes, visit www.aao.org/podcasts.

In this episode, Kelly Knickelbein, VMD, DACVO, joined us to discuss ocular squamous cell carcinoma in horses, including clinical signs, risk factors, treatment options, prevention strategies, and more. She also briefly discussed her current research on genetic cataracts in horses. This episode of Disease Du Jour is brought to you by Equithrive.GUESTS AND LINKS - EPISODE 169Host: Carly Sisson (Digital Content Manager) of EquiManagement | Email Carly (CSisson@equinenetwork.com)Guest: Dr. Kelly Knickelbein, VMD, DACVOPodcast Website: Disease Du JourThis episode of Disease Du Jour podcast is brought to you by Equithrive.Connect with the Host: Carly Sisson (Digital Content Manager) of EquiManagement | Email Carly (CSisson@equinenetwork.com)

Ocular complaints in children, such as a red or painful eye, sudden vision changes, or difficulty opening one eye, may be more than a minor concern. In pediatrics, these presentations can progress rapidly, and timely recognition is critical to preventing long-term vision impairment. A focused five-minute eye examination can often distinguish between emergent, urgent and routine conditions, making early assessment and intervention essential in the primary care setting.  This episode was recorded on the exhibit floor at the 2025 American Academy of Pediatrics National Conference in Denver, Colorado. Our guest is Donny Suh, MD, Professor of Ophthalmology and Chief of Pediatric Ophthalmology at the University of California, Irvine, and Children's Hospital of Orange County.  Some highlights from this episode include:  What a pediatrician can learn in five minutes  The most common ocular injuries that pediatrician's encounter  How pediatricians can support a patient before sending to a specialist  How understanding a patient's history can help a pediatrician For more information on Children's Colorado, visit: childrenscolorado.org. 

What if the brain fog you're experiencing isn't just tiredness—but your nervous system's way of disconnecting you from an unbearable reality? In this mini episode, Dr. Aimie Apigian answers a question from Rachel, a therapist in Seattle, about why the freeze response is associated with brain fog. Many people think of the freeze response as simply paralysis, not understanding the sophisticated biological mechanisms happening at the cellular level. This episode dives deep into the freeze response—when it happens, why it happens, and the brain inflammation that creates the disconnection and fog we experience. Understanding this biology helps us recognize when we or someone we're working with has a chronic functional freeze, so we know where to start with healing. In this episode you'll hear more about: The five steps the body takes to go into a trauma response—starting with activation and crossing the critical line of overwhelm The two reasons we cross that critical line: "too much too fast" (excessive activation) and "too little for too long" (prolonged stress without recovery) Why your nervous system decides certain situations are life threats—even when logically they're not (like being berated in residency or hearing hurtful words from someone you care about) The cellular biology of brain fog: How immune cells in your brain (microglia) unleash inflammation, cytokines, and chemokines that create the mental disconnection and fog The surreal feeling of freeze: Why voices sound distant, why you feel like you're in a daze, and why people around you seem far away even though they're right there Chronic functional freeze: The state where you're still functioning and going through life, but secretly wanting to hide, using substances like caffeine or food (especially histamine-producing foods) to push through Why anxiety is often your body fighting the freeze—using stress to stay out of shutdown, which is why relief from anxiety can sometimes make you fall into that heaviness The brain inflammation protocol: Specific nutrients and practices to keep your microglia in their resting state, including NAC, magnesium L-threonate, luteolin, GABA, resveratrol, and turmeric Ocular-cardiac reflex (eye support): A simple but powerful tool where gently pressing on closed eyes activates the vagus nerve for immediate calm Why starting with the freeze is essential—opening up the chronic functional freeze gives you more energy to dedicate to the healing journey Dr. Aimie's personal story of a biking accident and concussion—experiencing the freeze response firsthand as she regained consciousness on the sidewalk The freeze response isn't weakness or paralysis—it's your nervous system's sophisticated survival strategy when it perceives a life threat. Brain fog is always part of the freeze response, created by immune cells in your brain that help you disconnect from unbearable reality. Understanding this biology helps you recognize the freeze in yourself or others, and know that working with it is where healing must start.