Podcasts about World Conference

Featuring an interview with Dr Aaron Lisberg, including the following topics: Efficacy and Safety of Datopotamab Deruxtecan (Dato-DXd) for Patients with Previously Treated EGFR-Mutated Advanced Non-Small Cell Lung Cancer (NSCLC): A Pooled Analysis of the TROPION-Lung01 and TROPION-Lung05 Trials (0:00) Ahn M-J et al. Efficacy and safety of datopotamab deruxtecan (Dato-DXd) in patients (pts) with previously-treated EGFR-mutated advanced non-small cell lung cancer (NSCLC): A pooled analysis of TROPION-Lung01 and TROPION-Lung05. ESMO Asia 2024;Abstract LBA7 Ahn M-J et al. A pooled analysis of datopotamab deruxtecan in patients with EGFR-mutated NSCLC. J Thorac Oncol 2025;[Online ahead of print]. Abstract Sacituzumab Tirumotecan for Previously Treated Advanced EGFR-Mutated NSCLC: Results from the Randomized OptiTROP-Lung03 Study (7:08) Fang W et al. Sacituzumab tirumotecan versus docetaxel for previously treated EGFR-mutated advanced non-small cell lung cancer: Multicentre, open label, randomised controlled trial. BMJ 2025;389:e085680. Abstract Zhang L et al. Sacituzumab tirumotecan (sac-TMT) in patients (pts) with previously treated advanced EGFR-mutated non-small cell lung cancer (NSCLC): Results from the randomized OptiTROP-Lung03 study. ASCO 2025;Abstract 8507. Combination of Dato-DXd and Immunotherapy as First-Line Therapy for Patients with Advanced NSCLC (13:12) Cuppens K et al. First-line (1L) datopotamab deruxtecan (Dato-DXd) + durvalumab ± carboplatin in advanced or metastatic non-small cell lung cancer (a/mNSCLC): Results from TROPION-Lung04 (cohorts 2 and 4). ESMO Targeted Anticancer Therapies Congress 2025;Abstract 8O. Okamoto I et al. TROPION-Lung07: Phase III study of Dato-DXd + pembrolizumab ± platinum-based chemotherapy as 1L therapy for advanced non-small-cell lung cancer. Future Oncol 2024;20(37):2927-36. Abstract Levy BP et al. TROPION-Lung08: Phase III study of datopotamab deruxtecan plus pembrolizumab as first-line therapy for advanced NSCLC. Future Oncol 2023;19(21):1461-72. Abstract Aggarwal C et al. AVANZAR: Phase III study of datopotamab deruxtecan (Dato-DXd) + durvalumab + carboplatin as 1L treatment of advanced/mNSCLC. World Conference on Lung Cancer (WCLC) 2023;Abstract P2.04-02. TROP2-Targeting Antibody-Drug Conjugates as Neoadjuvant and/or Adjuvant Therapy for Patients with Resectable NSCLC (19:08) A phase III, randomised, open-label, global study of adjuvant datopotamab deruxtecan (Dato-DXd) in combination with rilvegostomig or rilvegostomig monotherapy versus standard of care, following complete tumour resection, in participants with Stage I adenocarcinoma non-small cell lung cancer who are ctDNA-positive or have high-risk pathological features (TROPION-Lung12). NCT06564844 Cascone T et al. Perioperative durvalumab plus chemotherapy plus new agents for resectable non-small-cell lung cancer: The platform phase 2 NeoCOAST-2 trial. Nat Med 2025;31(8):2788-96. Abstract CME information and select publications

Oracle (ORCL) issued more confidence in its A.I. expectations at its A.I. World Conference. Analysts across the board issued price target hikes and reiterated buys on the commentary. Despite the news, shares still slid on Friday's session. Marley Kayden breaks down the analyst notes with one calling Oracle a "decade stock."======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

The 2025 World Conference on Lung Cancer brings together leading experts, researchers, and oncologists to showcase the latest advancements in lung cancer research. To reach a global audience, IASLC has recorded podcast episodes on WCLC 2025 in world languages. In this episode, host Dr. Helena Linardou moderates a discussion in Greek about highlights from the conference with Dr. Foteinos-Ioannis Dimitrakopoulos and Dr. Evangelos Sarris.

In a recent candid conversation, Stassi Cramm, the first female prophet of the Community of Christ, discussed the Kirtland Temple sale & highly publicized sale of historic sites. She offered insights into the church's current financial & addressed the complexities of continuing to lead a worldwide, diverse body on issues of inclusion and mission. President Cramm, who was ordained in June 2025 and previously served nine years in the First Presidency, emphasized that her approach centers on faithful agility and discerning God's ongoing call for the church. https://youtu.be/blYLTxtHqVk Don't miss our other conversations with Stassi: https://gospeltangents.com/people/stassi-cramm/ Copyright © 2025 Gospel Tangents All Rights Reserved   Navigating Finances and Faith: An Update from Community of Christ President Stassi Cramm In a recent candid conversation, Stassi Cramm, the first female prophet of the Community of Christ, offered insights into the church's current financial reality following the highly publicized sale of historic sites, including the Kirtland Temple, and addressed the complexities of continuing to lead a worldwide, diverse body on issues of inclusion and mission. President Cramm, who was ordained in June 2025 and previously served nine years in the First Presidency, emphasized that her approach centers on faithful agility and discerning God's ongoing call for the church. -------------------------------------------------------------------------------- The $200 Million Kirtland Temple Sale Question: Financial Stewardship The sale of the Kirtland Temple and associated properties to the LDS Church generated almost $200 million. This revenue was immediately invested into the church's endowments, which are intended to provide some foundational income for the annual budget. However, Cramm confirmed a widespread projection that this sale alone did not generate enough to fully endow the operations of the church into perpetuity. The current financial model still relies significantly on Worldwide Mission Tithes (tithing) as an essential element of discipleship. Based on current trends, if the number of financial supporters continues to slowly decline, the Community of Christ will face additional financial questions around the year 2030. Cramm noted that the church's leaders, including the Council of 12 and the Presiding Bishopric, are focused on defining what the church "needs to be" in the future. The goal is not merely to keep the lights on, but to do so while faithfully being who God needs them to be in the world. This strategy involves: Fostering new communities of disciples committed to the church's mission. Engaging in social ministries and justice activities. Empowering new forms of leadership from younger generations. Innovating stewardship, including looking at different investment strategies and business ventures aligned with the church's mission. President Cramm concluded that success must be measured in faithfulness terms, rather than "worldly terms" like turning a profit or hitting a specific number of members in the pews. -------------------------------------------------------------------------------- Inclusion, Ordination, and the Gay Apostle Question The conversation also turned to the church's approach to LGBTQ+ inclusion, a topic that remains widely discussed both in the U.S. and within the global church. Community of Christ policy allows the World Conference to establish broad principles, while national or field conferences can weigh in on particulars based on local needs and discernment. This approach acknowledges that in some parts of the world, discussing inclusion topics can be life-threatening or illegal. When asked whether an openly gay apostle might be called under her administration, President Cramm emphasized a key distinction regarding ordination policy: Sexual Orientation is Not the Barrier: Cramm clarified that sexual ...

We're discussing 2 controversial topics with Stassi Cramm, President of the Community of Christ. We'll focus on the controversial sale of Kirtland Temple, as well as the schism that followed the 1984 revelation on women's ordination. Which was more controversial? Check out our conversation... https://youtu.be/CIv5kq-x648 1984 Schism & Its Aftermath The 1984 revelation that allowed women to hold the priesthood led to an immediate schism within the church, which was then known as the RLDS Church. President Cramm, who was not present at the 1984 conference, describes the period as rancorous with hard feelings. Following the decision, there were significant conflicts, including debates over property ownership and padlocks being put on church doors as whole congregations pulled away from the main body of the church. The opposition was so strong that a resolution to rescind the 1984 revelation was brought forward at the 1986 conference, though it did not pass. President Cramm contrasts this divisive experience with how the church handled the more recent, and also potentially divisive, issue of same-sex marriage in the early 2010s. Learning from the past, Church leadership approached the topic more slowly, with years of study and conversation. They developed "the principles of faithful disagreement," which allow members to hold differing opinions on church decisions without being judged as unfaithful. While the church still lost members after implementing new policies on same-gender marriage in 2013, the schism was not as severe as in 1984. Today, there are still members who do not believe women should be ordained, and some voiced their opposition to President Cramm's call at the most recent conference, which she notes is acceptable within the church's framework. Sale of Kirtland Temple A significant portion of the conversation addresses the recent sale of Kirtland Temple and other historic sites to The Church of Jesus Christ of Latter-day Saints. This decision was very difficult and emotional, comparable in some ways to the 1984 revelation. Key points regarding the sale: Lack of Conference Vote: The decision for the sale of Kirtland Temple was made by church leadership without a vote or formal input from the World Conference delegates. This was a major point of contention for members who felt the process contradicted the principle of common consent. A resolution was brought to the most recent conference demanding that future property sales receive conference approval, but it was ruled out of order. Rationale for Bypassing Conference: President Cramm explained that the resolution was ruled out of order because it conflicted with the scriptural and bylaw authority granted to the First Presidency and the Presiding Bishopric to act in the church's best overall interest. She also stated that giving 2,800 delegates enough information to make an informed recommendation was not feasible, and that leadership needed to be trusted to do their difficult job. Negotiation Secrecy: The negotiations on sale of Kirtland Temple were conducted under a non-disclosure agreement (NDA), which President Cramm described as a mutual decision to manage how information was released. A public debate or vote would have weakened the church's negotiating position, especially since it was determined that the LDS Church was the only entity capable of providing the necessary funds while ensuring the site's continued maintenance and accessibility. Financial Necessity: The sale was driven by a looming financial shortfall that threatened the church's ability to function globally. Leadership had a legal and moral obligation to keep the church operating and to ensure they could be good stewards of their properties. When it became clear they could no longer afford to properly maintain the temple, selling it was seen as the best option to preserve it. Response to "Revelation" Argument: When asked about the argument that the temple was given by...

The 2025 World Conference on Lung Cancer brings together leading experts, researchers, and oncologists to showcase the latest advancements in lung cancer research. To reach a global audience, IASLC has recorded podcast episodes on WCLC 2025 in world languages. In this episode, host Dr. Nagla Abdel Karim moderates a discussion in Arabic about highlights from the conference with Dr. Riad Abdeljalil, Dr. Khaled Abdel Aziz, Dr. Ashraf Abdel Ghani, Dr. Ahmed Rabea, and Dr. Hussein Soudy.

Stassi Cramm is the 1st female Prophet-President of the Community of Christ. I asked her to reflect back on the 1984 revelation that granted priesthood to women and her time as a lifelong member of Community of Christ. Was it hard? Check out our conversation... https://youtu.be/OjtLJ-FG988 Copyright © 2025 Gospel Tangents All Rights Reserved 0:00 Meet Stassi Cramm 4:32 Women Get Priesthood in 1984 Revelation 17:28 Diverse Agreement Look Back at 1984 Revelation on Women's Ordination Stassi Cramm, is the first female President of the Community of Christ. In 1984, was a young adult just starting her career in Southern California when the Community of Christ (then the RLDS Church) experienced a pivotal moment in its history: a revelation was presented that, among other things, opened the door for women to be ordained to the priesthood. For many, it was a moment of profound rightness. For others, it was a deeply divisive decision that would reshape the church for years to come. She recalls being "oblivious" to the years of study and conversation that led to this moment, as she had been busy with university and her new job. She wasn't at the 1984 World Conference where this new scripture, now Section 156 of the Community of Christ Doctrine and Covenants, was approved. News traveled slowly back then, through weekly long-distance phone calls and reports from conference attendees returning home. A Sense of Rightness Amidst Division When President Cramm finally read the new revelation, her reaction was immediate. "For me, there was this immediate sense of rightness to it and this sense of course! Why hadn't I thought of this before?" she recalls. She expresses a retrospective sense of shame that, as a woman in the male-dominated field of flight test engineering, she hadn't previously recognized the "lack of equal opportunity for leadership and service" in her own church. However, she soon learned of the "divisive nature" of the decision. People had walked out of the conference in protest, and the revelation sparked a schism within the church. Congregations split. Padlocks were put on church doors, and debates raged over property ownership. President Cramm's own congregation in Lancaster, California, handled the change well. But the wider church felt the strain. Personal Cost of a Calling Two years later, in 1986, Stassi Cramm received her first call to the priesthood. She remembers the vulnerability of that moment, standing before her stake conference as some members, including people she considered friends, raised their hands in opposition. "It's hard. You feel vulnerable anyways when you're accepting a call. And so when there's a group of people who raise their hand against you, intellectually you understand it. Emotionally you feel it". She credits the very first women who were ordained as her heroes, calling them "amazing path makers" who endured verbal criticism with humility and faithfulness. For herself, she chose to live in the difficult space of maintaining friendships with those who disagreed, recognizing that differing perspectives on whether the revelation was "of God" shouldn't sever their ability to be friends. This, she notes, is where Christlike love becomes a conscious choice, not a feeling—a choice to respect others' opinions even when you don't share them. Navigating Faithful Disagreement This experience highlights a core aspect of the Community of Christ's culture: navigating faithful disagreement. President Cramm later moved to a congregation in Las Vegas where a group remained opposed to women in the priesthood. The congregation found a way to coexist, making small accommodations for one another. For example, if a woman said the communion prayer, a male priesthood member would serve the sacrament to those who objected. These were hard conversations, but they were necessary to stay in community together. President Cramm shares a poignant memory of a conversation with a woma...

The 2025 World Conference on Lung Cancer brings together leading experts, researchers, and oncologists to showcase the latest advancements in lung cancer research. To reach a global audience, IASLC has recorded podcast episodes on WCLC 2025 in world languages. In this episode, host Dr. Chul Kim moderates a discussion in Korean about highlights from the conference with Dr. Jeongmin Seo and Dr. Min Hee Hong. Guest Host: Chul Kim, MD, MPH Thoracic Medical Oncologist and Associate Professor Georgetown University Instagram: @fe0120 Guest Name(s) & Title(s): Jeongmin Seo, MD, MSc Assistant Professor, Medical Oncology Seoul National University Bundang Hospital Min Hee Hong, MD Associate Professor, Yonsei Cancer Center Severance Hospital, Seoul

Join us in this episode of the Oncology Brothers podcast as we dive into the highlights from the World Conference on Lung Cancer 2025! We are joined by Dr. Balazs Halmos, a thoracic medical oncologist at the Montefiore Einstein Cancer Center, to discuss three pivotal studies that are shaping the future of lung cancer treatment. In this episode, we covered: •⁠  ⁠FLAURA2 Trial: Discover the significant overall survival benefits of combining osimertinib with chemotherapy for patients with EGFR-positive non-small cell lung cancer, and how it compares to single-agent osimertinib. •⁠  ⁠HARMONi Trial: Explore the intriguing yet complex findings of a new bi-specific antibody targeting PD-1 and VEGF in patients with progressive EGFR-mutated disease, and the implications of its current negative results. •⁠  ⁠ALCHEMIST Trial: Learn about the role of crizotinib in the adjuvant setting for ALK-positive lung cancer and why it reinforces alectinib as the standard of care. Tune in for an insightful discussion on the latest advancements in precision medicine, the importance of ctDNA, and the evolving landscape of lung cancer treatment.  Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ Don't forget to like, subscribe, and hit the notification bell for more updates from the Oncology Brothers!

The 2025 World Conference on Lung Cancer brings together leading experts, researchers, and oncologists to showcase the latest advancements in lung cancer research. To reach a global audience, IASLC has recorded podcast episodes on WCLC 2025 in world languages. In this episode, guest host Dr. Kuan Yu Chen moderates a discussion in Mandarin with Dr. Bin-Chi Liao and Dr. Jeng-Sen Tseng, leading lung cancer experts in Taiwan, who share their perspectives on key highlights from the conference.

The 2025 World Conference on Lung Cancer brings together leading experts, researchers, and oncologists to showcase the latest advancements in lung cancer research. To reach a global audience, IASLC has recorded podcast episodes on WCLC 2025 in world languages. In this episode, host Dr. Clarissa Mathias moderates a discussion in Portuguese about highlights from the conference with Dr. Clarissa Baldotto, Dr. Lilian Faroni, Dr. Maria Cecilia Mathias, and Dr. Wiliiam William, Jr.

A conversation with Doris Viljoen about the upcoming WFSF World Conference in South Africa 29 to 31 October 2025

On this week's episode, Chris Garabedian, Tess Cameron, EricSchmidt, Sam Fazeli, and Brad Loncar open with a look at the market environment as biotech sees its first IPO since February -- LB Pharma -- and financings, including Maze's $150M PIPE and Rapport's $250M follow-on. The co-hosts discuss improving sentiment around rates, the $XBI, and insights from conversations at the HC Wainwright conference. Novartis' $1.4B acquisition of Tourmaline Bio and broader deal-making dynamics are also highlighted. On thepolicy front, the group examines the latest China biotech news, including a draft executive order from the Trump Administration. The co-hosts debate access, geopolitical concerns, and the FDA's slower trial-startup process. Indata news, the co-hosts examine Revolution Medicines' pancreatic cancer therapy, emerging small-cell lung cancer data from the World Conference on Lung Cancer, Summit's mixed readout and market reaction, and promising newnarcolepsy data from Takeda and Alkermes. Dianthus' positive generalized myasthenia gravis results are also highlighted. Regulatory and safety updates cover the FDA's withdrawal of Intercept's liver drug, a patient death in Capsida's gene therapy trial, Soleno's FAERS-related stock drop, SEC action on Fibrogen data manipulation, and cancellations of several FDA ad comms raising transparency questions. The episode concludes with a discussion on BridgeBio accusing Alnylam and Pfizer of aggressive tactics in the ATTR-CM market, Arena Bioworks appointing veteran Harvey Berger as CEO, and Novo Nordisk's 11% workforce reduction. *This episode aired on September 12, 2025.

The 2025 World Conference on Lung Cancer just concluded, and there are several notable updates concerning treatment of EGFR-mutated NSCLC. 1. The COMPEL study tries to find the value of continuing osimertinib (with the addition of chemotherapy) after progression on osimertinib. The results are, well, compelling! 2/3. We now have updates on the OS benefits of osimertinib + chemotherapy (FLAURA2) and amivantamab + lazertinib (MARIPOSA) compared to osimertinib monotherapy in initial treatment of metastatic disease. 4. NEOADAURA tries to determine if neoadjuvant osimertinib has value, but longer follow-up will be needed to assess this practice.

The 2025 World Conference on Lung Cancer brings together leading experts, researchers, and oncologists to showcase the latest advancements in lung cancer research. To reach a global audience, IASLC has recorded podcast episodes on WCLC 2025 in world languages. In this episode, host Dr. Alona Zer moderates a discussion in Hebrew about highlights from the conference with Dr. Haitam Nasrallah, Dr. Jair Bar, and Dr. Ory Wiesel.

The Make America Healthy Again Commission released itssecond report Tuesday, recommending, among other efforts, an investigation into a possible link between vaccines and the uptick in chronic disease. At a livestreamed MAHA commission meeting, Health Secretary Robert F. Kennedy painted a dire picture of the country's health, saying the U.S. now has “the highest chronic disease burden of any country in the world.” Looking back to last week, all eyes were on HealthSecretary Robert F. Kennedy Jr.'s appearance before the Senate Finance Committee. The combative showdown amounted to little more than political theater, according to industry watchers, with Kennedy accusing former CDC Director Susan Monarez of lying in an op-ed published in the Wall Street Journal about his alleged request that she approve vaccine advisors' recommendations in advance of their meeting later this month.Over at the FDA, BioSpace combed through the latest cache of publicized complete response letters (CRLs), including one for Lykos' MDMA-based therapeutic for post-traumatic stress disorder. Going forward, the agency has promised to release CRLs in real time. The greater transparency could help companies spinning on a carousel of confusion caused by all the recent regulatory change. In other FDA news, we take a deep dive into new expert panels, which some commentators view as one-sided, and into the new rare disease approval framework, which one critic called “all wrapper and no gift.” And in the weight loss space, the FDA debuted a consumer “green list” for GLP-1 ingredients. Meanwhile, at the World Conference on Lung Cancer inBarcelona, several data readouts caught our attention. In particular, Summit Therapeutics released disappointing data for its PD-L1/VEGFa bispecific antibody ivonescimab in Western populations—a finding some analysts said could have readthroughs to Bristol Myers Squibb/BioNTech's first ever global data readout for its L1/VEGFa bispecific.Finally, in Biopharm Executive this week, check out features on contingent value rights, which have been getting tacked on to biopharma deals more and more, Amgen's pipeline beyond the obesity drug MariTide and Novartis' recent deal spree, which included the $1.4B acquisition of Tourmaline on Tuesday.

Guest: Paola Marignani, PhD, EMBA While smoking remains a key risk factor for lung cancer, up to 25 percent of cases occur in people who have never smoked, leaving significant gaps in our understanding of causation and diagnostics. Dr. Paola Marignani explores emerging discoveries in gene variants unique to never-smokers, uncovered through single-cell RNA sequencing and machine learning. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.

Guest: Paola Marignani, PhD, EMBA While smoking remains a key risk factor for lung cancer, up to 25 percent of cases occur in people who have never smoked, leaving significant gaps in our understanding of causation and diagnostics. Dr. Paola Marignani explores emerging discoveries in gene variants unique to never-smokers, uncovered through single-cell RNA sequencing and machine learning. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.

The 2025 World Conference on Lung Cancer brings together leading experts, researchers, and oncologists to showcase the latest advancements in lung cancer research. To reach a global audience, IASLC has recorded podcast episodes on WCLC 2025 in world languages. In this episode, host Dr. Narjust Florez moderates a discussion in Spanish about highlights from the conference with Dr. Laura Mezquita and Dr. Jorge Alatorre Alexander.

JCO fellow Dr. Ece Cali speaks with JCO Associate Editor Dr. Thomas E. Stinchcombe to discuss the JCO article "Phase 2 Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non-Small-Cell Lung Cancer with Epidermal Growth Factor Receptor Exon 20 Insertion Mutations (WU-KONG1B)", that was simultaneously released at the IASLC 2025 World Conference on Lung Cancer. TRANSCRIPT Dr. Ece Cali: Hello, and welcome to our series where we cover some of the top JCO papers published simultaneously with their abstract presentation at this year's most important oncology meetings. I am your host, Dr. Ece Cali, JCO editorial fellow, and I am joined by Dr. Tom Stinchcombe, JCO associate editor, to discuss the Journal of Clinical Oncology article and 2025 World Conference on Lung Cancer abstract presentation, “Phase II Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non–Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations.” The WU-KONG1B trial is a multinational, phase II study that investigated the efficacy and safety of different doses of sunvozertinib in patients with metastatic non-small cell lung cancer and EGFR exon 20 insertion mutations after progression on platinum based chemotherapy. Tom, before we dive into the results, could you walk us through the rationale for this study, and how does it fit into the current treatment options for patients with EGFR exon 20 insertion? Dr. Tom Stinchcombe: Thank you, Dr. Cali. I think the clinical context is always important. We have known that EGFR exon 20 insertions exist and that they are resistant to our currently available EGFR tyrosine kinase inhibitors, and I think there have been attempts in the past to develop a tyrosine kinase inhibitor, but there is a very narrow therapeutic window between the dose you need to inhibit the EGFR mutation in the cancer and the EGFR receptor on normal tissues, most notably the mucosa, the gut, and the skin. And so, our previous attempts have failed largely because the dose required was not tolerable for patients and they could not really stay on the drug for a long time or they were not very active. And so, I think there was a real desire to develop an EGFR tyrosine kinase inhibitor, and then, historically, the standard had been a platinum based doublet as the standard of care. And more recently, platinum based doublet with amivantamab has proven to be superior to platinum based chemotherapy alone. I think the context is also important that amivantamab is not necessarily available in all the countries, and so, there are patients who do not have access to amivantamab. Going to the rationale, I think that this drug had shown preliminary promise of having activity but without that being encumbered by those EGFR wild type toxicities, and, therefore, it was really explored in this larger study. Dr. Ece Cali: And what are some key findings from this trial? Dr. Tom Stinchcombe: So, I think that we should look at the study design. It is a little quirky, for lack of a better term, in that there is a randomization to 200 versus 300 mg, and then, there was a nonrandomized cohort of 300 mg. So, when you look at the study, if you are a purist, you will just look at the randomized patients. If you are sort of an aggregator, you look at all patients. So, it shows reporting on three cohorts, but I think the key findings are that the 200 mg and the 300 mg treatments had similar toxicities in terms of response rate, duration of response, and progression free survival. And as you know going through the review, there was a lot of queries from the reviewers as to which would be the preferred dose, and to me, I think this really illustrates a dose finding component to a trial design because there is a lot of debate about what the minimal effective dose is or the optimal dose. And in this case, having the two dose cohorts did provide us some valuable efficacy and toxicity information. And then, when I look at the study, I want to make sure it reflects my patient population, and about a quarter of patients had brain metastases, and about 15% had previous amivantamab, and about 5% to 10% had another EGFR tyrosine kinase inhibitor. Dr. Ece Cali: And what is the objective response rate and the duration of response? These are pretty good numbers for this patient population. Dr. Tom Stinchcombe: In the 200 mg cohort, it was about 46%. The duration of response was around 11 months, and the PFS was around 8 months. The 300 mg cohort was 46%, duration of response 9.8, and the median PFS is 6.9 months, and I think that this is greater activity than we have seen with our previous attempts at EGFR tyrosine kinase inhibitors. Dr. Ece Cali: And based on these data, FDA granted accelerated approval for sunvozertinib very recently at 200 mg once daily dosing in this setting. So, that is a major step forward for our patients. Dr. Stinchcombe, how does this impact your clinical practice, and what side effects should oncologists be watching for if they prescribe this medication? Dr. Tom Stinchcombe: So, I think it was very interesting that they chose the 200 mg dose, which I think was more tolerable, and when we kind of look at this, there still was a rate of diarrhea, all grade, rash, paronychia, which are the EGFR related toxicities. There can be some decreased appetite, stomatitis, and then, it can lead to some lab abnormalities, like increased CPK and creatinine that physicians have to be aware of. You know, how it will affect my practice is that all these patients had received a platinum based chemotherapy as the first line therapy. I think that this would become my preferred second line therapy for patients outside the context of a trial because of the activity and the tolerability. Dr. Ece Cali: And lastly, several other tyrosine kinase inhibitors are being evaluated for EGFR exon 20 insertion, including in the frontline setting. So, what are some of the outstanding questions in this space, and what data should our listeners keep an eye on moving forward? Dr. Tom Stinchcombe: I think you are right that now, there is going to be another EGFR tyrosine kinase that may become available in the next year, and there is another drug, furmonertinib, that is being investigated. I think, for the clinical question, is, well, can we move these into the first line setting? And actually, the development path has two ways of doing this. There is EGFR tyrosine kinase compared to platinum based chemotherapy, and then, platinum based chemotherapy with an EGFR tyrosine kinase versus platinum based chemotherapy, and both have their merits and strengths. And so, I think it is going to be very interesting as we see if those first line trials, one, can they be demonstrated to be superior to platinum based chemotherapy, and then by what magnitude and what the side effects are. But I think we are hoping that in the next couple of years, we will have an additional first line option for our patients. Dr. Ece Cali: Yeah, it is always great to have more options for our patients. Thank you, Dr. Stinchcombe, for speaking about the JCO article, “Phase II Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations.” Join us again for the latest JCO simultaneous publications. Please take a moment to rate, review, and subscribe to all ASCO podcast shows at asco.org/podcasts. Until then, enjoy the rest of World Lung Conference. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.  

Guest: Paola Marignani, PhD, EMBA Single-cell RNA sequencing is transforming our understanding of tumor heterogeneity in primary lung cancers by offering insights far beyond traditional bulk sequencing. In this program, Dr. Paola Marignani explores how advanced machine learning enables faster, more precise profiling of genetic diversity, predictive modeling for recurrence and drug resistance, and personalized treatment strategies. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.

Guest: John Cho, MD, PhD, FRCPC While early findings using the SMART protocol for mesothelioma have been encouraging, replication has proven challenging due to steep surgical learning curves, complexities in planning, and skepticism. Dr. John Cho explores why adoption has been limited and what's next for this approach, which he discussed at the 2025 World Conference on Lung Cancer. Dr. Cho is a radiation oncologist at Princess Margaret Cancer Centre and an Associate Professor in the Department of Radiation Oncology at the University of Toronto.

Guest: John Cho, MD, PhD, FRCPC Surgery for mesothelioma after radiation therapy (SMART) offers new hope for patients with resectable epithelioid mesothelioma by reversing the traditional treatment sequence. Hear from Dr. John Cho as he discusses the rationale behind this decade-long clinical advancement, which he spoke about at the 2025 World Conference on Lung Cancer. Dr. Cho is a radiation oncologist at Princess Margaret Cancer Centre and an Associate Professor in the Department of Radiation Oncology at the University of Toronto.

Guest: John Cho, MD, PhD, FRCPC While early findings using the SMART protocol for mesothelioma have been encouraging, replication has proven challenging due to steep surgical learning curves, complexities in planning, and skepticism. Dr. John Cho explores why adoption has been limited and what's next for this approach, which he discussed at the 2025 World Conference on Lung Cancer. Dr. Cho is a radiation oncologist at Princess Margaret Cancer Centre and an Associate Professor in the Department of Radiation Oncology at the University of Toronto.

Guest: John Cho, MD, PhD, FRCPC Surgery for mesothelioma after radiation therapy (SMART) offers new hope for patients with resectable epithelioid mesothelioma by reversing the traditional treatment sequence. Hear from Dr. John Cho as he discusses the rationale behind this decade-long clinical advancement, which he spoke about at the 2025 World Conference on Lung Cancer. Dr. Cho is a radiation oncologist at Princess Margaret Cancer Centre and an Associate Professor in the Department of Radiation Oncology at the University of Toronto.

Guest: Paola Marignani, PhD, EMBA Single-cell RNA sequencing is transforming our understanding of tumor heterogeneity in primary lung cancers by offering insights far beyond traditional bulk sequencing. In this program, Dr. Paola Marignani explores how advanced machine learning enables faster, more precise profiling of genetic diversity, predictive modeling for recurrence and drug resistance, and personalized treatment strategies. Dr. Marignani is a Professor in the Department of Biochemistry and Molecular Biology at Dalhousie University in Halifax, Novia Scotia, and she spoke about this topic at the 2025 World Conference on Lung Cancer.

The 2025 World Conference on Lung Cancer brings together leading experts, researchers, and oncologists to showcase the latest advancements in lung cancer research. To reach a global audience, IASLC has recorded podcast episodes on WCLC 2025 in world languages. In this episode, host Dr. Chunxia Su moderates a discussion in Mandarin Chinese about highlights from the conference with Dr. Yang Xia and Dr. Nan Bi.

Dublin's Trinity College researchers have announced a potential breakthrough in relation to a cancer that kills up to 50 people a year. The offending condition is called Mesothelioma the team lead is Prof Patrick Forde and he joined us from the World Conference on Lung Cancer in Barcelona.

In this episode of Lung Cancer Considered, Dr. Narjust Florez and Dr. Stephen Liu share tips for first-time attendees of the World Conference on Lung Cancer (WCLC). Recorded live at WCLC 2025, hear their 10 key recommendations to make the most of your experience, including advice on how to sneak self-care into your busy conference schedule.

The Community of Christ has sold the Kirtland Temple and several Nauvoo properties to the LDS Church for a jaw-dropping $200 million. But RLDS finances are still shaky! That money is only expected to keep the church afloat for about five years. Historian John Hamer joins us to explain why he thinks the deal could have been much better, why he's disappointed there are still no openly gay apostles, and to share his brutally honest thoughts on Steven Veazey's leadership. Stick around—this conversation pulls no punches. John is the co-author of Scattering of the Saints: Schism Within Mormonism. https://youtu.be/F3sTvJCWD3c Don't miss our other episodes with John Hamer! https://gospeltangents.com/people/john-hamer/ Copyright © 2025 Gospel Tangents All Rights Reserved Deep Dive into the Kirtland Temple Sale & Path Forward The recent sale of the Kirtland Temple sent shockwaves through the Latter Day Saint movement, and for the Community of Christ (formerly RLDS). It highlighted significant and ongoing financial challenges. John Hamer, a Community of Christ historian and Seventy, has offered candid insights into the church's financial state, the controversial temple sale, and his hopes for the future. Kirtland Temple Sale: A "Pittance" and a Crisis of Legitimacy The sale of the Kirtland Temple to the Church of Jesus Christ of Latter-day Saints (LDS Church) for less than $200 million was a deeply troubling event for many in the Community of Christ. John Hamer describes the price as a "pittance," emphasizing that the property's value, particularly in terms of "legitimacy" for the LDS Church, is "priceless" and far exceeds the sale amount. He provocatively suggests that the LDS Church, with its "hundreds of billions of dollars," would not sell the temple for even $200 billion. A major point of contention was the lack of transparency and consultation surrounding the sale. The decision was made "in secret," without any input from the World Conference, the church's "giant legislature". This went against historical precedent, as a previous General Conference had determined that a revelation would be necessary to sell the Kirtland Temple, which had originally been built by revelation. Hamer views the sale as a missed opportunity, stating that it was sold for "a third of what was necessary" for the church to achieve a "sustainable endowment for operations" (which he estimates would have required $600 million.) He suggested that a wealthy family foundation within the Community of Christ could have acquired the assets for the same price, held them as an investment, and then sold them to the LDS Church for a significantly higher amount later, but this option was not considered. Broader RLDS Financial Woes and Leadership Accountability The Kirtland Temple sale is just one symptom of deeper financial struggles within the Community of Christ: Declining Tithing to Headquarters: Over the 20-year tenure of former prophet-president Steve Veazey, "tithing to headquarters... has gone down so precipitously," with only around 6,000 members in the United States and Canada contributing to the world church. Hamer attributes this partly to members feeling their input is ignored when resolutions from the World Conference are ruled "out of order" by the executive leadership. High Operating Costs: The Community of Christ headquarters apparatus costs approximately $2.5 million annually to operate, while its current income is less than $10 million. Unsustainable Endowment: The endowment established to perpetually fund the Independence Temple was, in Hamer's opinion, "invested not like a responsible investor would do" and became "not worth anything" during Veazey's leadership. Unfunded pension obligations also contributed to the financial crisis. Short-Term Fix: The $200 million from the Kirtland Temple sale is projected to sustain headquarters only until "up through 2030," after which "anything goes".

Dinkar P. Srivastava joined the Indian Foreign Service in 1978. He has served in Karachi in the early 90s. Also served in the Middle East, Washington, Brussels and Tehran.In 1993-94, as Director (UNP), he was part of successful Indian lobbying efforts against four Pakistani attempts to have resolutions on J&K adopted in UN General Assembly and UN Commission on Human Rights. He was involved in the drafting of National Human Rights Commission statute. As Joint Secretary (UNP), he participated in Indian lobbying efforts to contain the diplomatic fallout of the Pokhran II nuclear tests and prevent the internationalization of the J&K issue during the Kargil war (1999).He dealt with Indian candidature for permanent membership of the UN Security Council, UN Peace-keeping and Comprehensive Convention on International Terrorism. He was a member of the Indian delegations to the World Conference on Human Rights in 1993, and the International Court of Justice in the case of Aerial Incident of 1999 (Pakistan v. India). In 2011-15, as Indian Ambassador to Iran, he negotiated the MOU for Indian participation in Chabahar Port.His book 'Forgotten Kashmir: The Other Side of the Line of Control' examines the evolution of Pakistan-Occupied Kashmir (POK) over the past seven decades. His latest book 'Pakistan: Ideologies, Strategies, Interests' examines the ideology of Pakistan

Changes in RLDS Succession Last Spring, John Hamer gave a monumental address about RLDS succession at the JWHA Meetings that literally changed RLDS History. Pres-prophet Steven Veazey had announced his pending retirement in 2 years and said he would choose a successor. John argued in his address that if Veazey did so, it would make his presidency illegitimate as well as whoever he picked. So, the process was changed as a result of his address. He'll give more details. Check out our conversation... https://youtu.be/2rQnCWIYxqE John is the co-author of Scattering of the Saints: Schism Within Mormonism. Don't miss our other episodes with John Hamer! https://gospeltangents.com/people/john-hamer/ Copyright © 2025 Gospel Tangents All Rights Reserved From Monarchical Tendencies to a "Prophetic People" Historically, leadership in the Reorganized Church of Jesus Christ of Latter Day Saints (RLDS), now Community of Christ, was heavily influenced by the Joseph Smith lineage. Joseph Smith III's succession, recognized by the General Conference (World Conference), established two pillars of legitimacy: appointment by the predecessor and the "royal line" of Joseph Smith, which was seen as holy according to the Book of Mormon. William Smith, brother of Joseph Smith, actively promoted the idea of a Smith "royal seed," drawing parallels to James, the brother of Jesus, leading the early Christian church. However, this tradition soon saw shifts. Joseph III's son, Frederick M. Smith, introduced the concept of "supreme directional control," concentrating power in the First Presidency, which he led. This led to significant internal conflicts, including the resignation of the entire Presiding Bishopric and the departure of prominent figures like R.C. Evans, who felt sidelined despite his own aspirations for leadership. The Smith lineage continued through Joseph III's sons until Wallace B. Smith, a grandson, took the helm. He was a "progressive leader" who, in 1984, initiated the end of priesthood discrimination based on gender (D&C 156), a move that led to schism within the church as "restorationist" groups broke away. Importantly, Wallace B. Smith broke from the Smith lineage tradition by appointing a non-Smith, W. Grant McMurray, as his successor. Grant McMurray's tenure marked another pivotal shift. In D&C 162, he articulated a vision of the church as a "prophetic people, not just a people with a prophet," introducing a new pillar of legitimacy that emphasized discernment and input from the wider church body. This concept challenged the previous monarchical tendencies and opened the door for more democratic forms of leadership. Crisis and Controversy: The Kirtland Temple Sale and Succession Plans Grant McMurray's abrupt resignation in 2004, without appointing a successor, created a succession crisis, effectively breaking the chain of appointment. In response, a special World Conference was called, and the First Presidency assigned the Council of Twelve Apostles to choose the next prophet, who turned out to be Steve Veazey. Steve Veazey's 20-year presidency, however, was marked by significant financial struggles for the church, leading to an "unmitigated decline". This culminated in the controversial sale of the historic Kirtland Temple for less than $200 million. Critics, including historian John Hamer, argued that the sale was conducted "in secret" and for "a pittance," insufficient for the church's long-term financial sustainability. The World Conference had previously required a revelation to sell the Kirtland Temple, highlighting the lack of transparency in the recent transaction. Adding to the controversy, Steve Veazey announced a plan to personally select his successor. John Hamer publicly argued that this move would "retroactively completely delegitimize" Veazey's tenure and render his chosen successor illegitimate, as it contradicted the principle of a "prophetic people" and the broken chain of appo...

Claire de Mézerville López welcomes IIRP alumnus Joseph Iacona to the Restorative Works! Podcast. We are joined by Joseph as he takes us behind the scenes of projects in schools, libraries, prisons, shelters, and behavioral health facilities, revealing how restorative practices create authentic collaboration between artists and communities. He shares powerful stories, including a mural co-created with youth aging out of the foster care system—a project that evolved into a living, breathing space of connection and care years after the paint dried. As a featured speaker at the IIRP's upcoming World Conference on Artful Integration, Joseph offers a preview of his presentation on the parallels between successful public art projects and restorative leadership. He issues a call to action for more intentional partnerships between artists and restorative practitioners to use art as a tool for authentic collaboration and social change. Joseph is a visual artist and restorative practitioner. He has initiated more than 100 community art projects in schools, libraries, museums, prisons, shelters, behavioral health facilities, and other public service centers. As the director of the Mural Arts Institute for Mural Arts Philadelphia, the United States' largest public art nonprofit, he develops resources on community driven mural-making for other artists and public art advocates around the world. Joseph holds a Master of Science in Restorative Practices with a specialization in Community Engagement from the IIRP and a Bachelor of Fine Art with concentrations in painting and art history from Kutztown University of Pennsylvania. He's an upcoming featured speaker at the IIRP's next World Conference on Artful Integration, Exploring the Art and Science of Restorative Practices. Tune in to hear more from Joseph as he explores how defining “community” is an essential first step, and how tools like narrative mapping can uncover shared values and vision.

NPR, Mayor Frm Legislator, Councilman, U.S. Presidential Appointee, AmbassadorFord got his start in politics working for U.S. Sen. Robert Kennedy's presidential campaign, and he later worked for the U.S. Department of Justice Community Relations Service.A native of the great State of Alabama, Johnny Lawrence Ford grew up in Tuskegee, the home of Tuskegee University, “the Pride of the Swift-Growing South,” also the home of the famed Tuskegee Airmen. He graduated from Tuskegee Institute High School and received his B.A. degree in history and sociology from Knoxville College, Knoxville, Tennessee, and a Masters of Public Administration from Auburn University at Montgomery. He also received 5 honorary degrees including The Honorary Doctorate of Laws from Alabama A & M University in 2004.Elected as the 1st African-American Mayor of the City of Tuskegee in 1972, Mayor Ford served six consecutive terms from 1972 – 1996 and was again elected to that office in September, 2004 and 2012. In 1998, he was elected Representative from District 82 to the State Legislature, where he served on the County and Municipal Government Committee, the Lee County Legislation Committee, the Health Committee, and the Tourism and Travel Committee. The Honorable Ford retained his legislative position until his return to office as mayor of Tuskegee.As Founder of the World Conference of Mayors, Inc., The Honorable Ford also serves as Secretary General. He is a Founder and President-Emeritus of the National Conference of Black Mayors, Inc., and a former member of the Alabama Foreign Trade Commission and the Alabama Municipal Electric Authority. While Mayor, Banjul, The Gambia was designated as the Tuskegee Sister City; therefore, he has worked closely with the country, The Gambia, for many years. Furthermore, he has served as Co-Chairman of the National Policy Alliance, which is an arm of the Joint Center for Political and Economic Studies. The National Policy Alliance Center for Political and Economic Studies is comprised of The National Bar Association, The Congressional Black Caucus, The World Conference of Mayors, The National Conference of Black Mayors, The National Association of Black County Officials, The National Black Caucus of School Board Members, Blacks in Government, The National Black Caucus of Local Elected Officials, as well as the Joint Center For Political and Economic Development.The Honorable Ford has served as a former U.S. Presidential Appointee to the National Advisory Committee on Federalism, and the Intergovernmental Policy Advisory Committee on Trade. He is a past President of the Alabama League of Municipalities, and the first African-American in Alabama History to be elected to this statewide position.He is married to the Honorable Judge Joyce London Alexander, Retired, Former Chief U. S. Magistrate Judge, of the District of Massachusetts. She was the First Female Chief United States Magistrate Judge in the USA. She is Past Chair of the Judicial Council of the National Bar Association, and of the Board of the Joint Center for Political and Economic Studies.He is also the proud father of three adult children…John, Christopher, and Tiffany…The Honorable Ford has four grandchildren. The Fords have a second home on Garden Street in Cambridge, Massachusetts.© 2025 Building Abundant Success!!2025 All Rights ReservedJoin Me on ~ iHeart Media @ https://tinyurl.com/iHeartBASSpot Me on Spotify: https://tinyurl.com/yxuy23baAmazon Music ~ https://tinyurl.com/AmzBASAudacy:  https://tinyurl.com/BASAud

We'll discuss controversial RLDS beliefs with John Hamer, a Seventy with the Community of Christ. We're focusing on the 1844 succession crisis, its lasting impact on both the LDS and Community of Christ (formerly RLDS) churches. He's the co-author of Scattering of the Saints: Schism Within Mormonism. Don't miss this fascinating discussion! https://youtu.be/mscrLYLKZs0 00:00 How 1844 Succession Affects Us Today 8:15 How Baptism For Dead Was De-canonized 14:22 Will Book of Mormon Be De-canonized? 24:10 Black Priesthood in Community of Christ 36:37 3 Official Languages in CoC Copyright © 2025 Gospel Tangents All Rights Reserved Succession Crisis and its Legacy: ◦ The 1844 schism "froze" both churches into peculiar systems, as each justified its own succession to assert legitimacy. ◦ LDS Church Succession: Brigham Young's claim relied on his position as the senior-most apostle, a concept that was not established doctrine in 1844 but emerged from the crisis. ◦ Community of Christ (RLDS) Succession: Joseph Smith III's claim was supported by patriarchal blessings and prophecies. His acceptance of the prophet role in 1860 solidified the General Conference's (legislative) authority to choose the prophet. Sidney Rigdon also made a claim to leadership, presenting himself as a "guardian of the church.” ◦ The Mark Hofmann forgery of Joseph Smith Jr.'s blessing to Joseph Smith III is discussed, noting its incorrect date caused dissonance Jerald & Sandra Tanner. It was acquired by the LDS Church, which then traded it to the RLDS Church for a copy of the Book of Commandments. The RLDS Church put it in the appendix of their version of the Doctrine & Covenants & then later removed this forgery from its historical appendix through a "historical appendectomy.” RLDS Doctrine and Covenants and De-canonization: ◦ The Community of Christ's Doctrine and Covenants is an active scripture, with new sections added through votes by elected representatives at World Conferences. The conference also has the power to remove sections, which it has done several times. ◦ Baptism for the Dead: This practice was removed from the RLDS Doctrine and Covenants, largely due to the church's desire to distance itself from associations with LDS temples and practices, particularly those perceived as "secret" or "embarrassing.” John Hamer expresses a nuanced view, considering it meaningless as a necessary saving ordinance for random names but "incredibly valid and amazing" as a spiritual practice for connecting with cherished ancestors (e.g., Jane Manning James). ◦ Blacks in the Priesthood (RLDS): Joseph Smith III's 1860s revelation allowed black men to hold the priesthood but included a racist caveat to "be not hasty" in ordaining them, reflecting the prevailing societal racism of the 1860s. A recent World Conference resolution to remove this section was voted down, with John Hamer arguing against removal to avoid setting a precedent of "Jefferson Bible" editing scripture. ◦ De-canonization of the Book of Mormon: There's a "dig" (and potential validity) that the Community of Christ "doesn't believe in the Book of Mormon" in the same way other groups do. Some leaders and members, traumatized by the "New Mormon History" and historical-literary criticism suggesting the Book of Mormon is a 19th-century construct, have proposed to "jettison all of this stuff.” However, others, especially older members, find it essential to their identity. John Hamer "firmly anticipates" a resolution to remove the Book of Mormon from the canon, though he personally opposes it. Understanding Scripture: ◦ John Hamer advocates for viewing scripture as "errant, not inerrant.” He believes scripture is a "human response to God's revelation," filled with the "biases and limitations of every prophet.” ◦ He argues against treating scripture as a "perfect idol" or a "literalistic rule book," emphasizing that doing so misses its true meaning and preve...

We are delighted to partner with the Writers' Guild of Ireland to bring you 2 very special podcasts of panels and discussions from the 2024 World Conference of Screenwriters, an international gathering of screenwriters and Writers Guilds' from all around the world, which took place in Galway, 2 – 3 October 2024. Day 2 This second podcast features Day 2's proceedings, beginning with: Globalising Screen Industries: Balancing Inward Production and Domestic Screenwriting Talent This panel delves into the dynamics of globalised production and the implications for screenwriters worldwide. As the influx of inward production persists, often sidelining domestic writing talent, the panel examines the risks inherent in developing an industry heavily reliant on external service productions and share strategies to encourage more domestic projects. Speakers Alice Shearman Rachel Kilfeather Gabor Krigler Bruce M. Smith Lesley Gannon In Conversation with the WGA East and WGA West This conversation takes a deep dive into the organisation of 2023''s WGA negotiations and strike. [from 1hr 04mins] Speakers Josep Gatell David Goodman Meredith Stiehm Chris Keyser Lisa Takeuchi Cullen Roddy Who? A Commitment to Credits This panel explores how credits for screenwriters and producers diverge in different territories. The discussion analyze why showrunners sometimes belong in one category and sometimes in the other, and yet it's still not a recognized credit, how much the “created by” credit matters, who's getting it, and the value of a global standard for credits. [from 2hr 05mins] Speakers Denis Goulette Barbara Petronio Emma Reeves Betsy Thomas Marcus Seibert Artificial Intelligence A conversation on what's being done to protect screenwriters, and what they need to do next. [from 2hr 59mins] Speakers Jennifer Davidson Dr Abigail Rekas Ellen Stutzman Victoria Shen David Kavanagh KEYNOTE SPEECH: The Future is Unwritten Speakers [from 3hr 45mins] Laura Slattery Terry George Liaten back to Day 1 https://filmireland.net/2025/04/18/wcos-podcast-2024-world-conference-of-screenwriters-day-1/ https://script.ie/ https://filmireland.net/

I was in a zoom meeting today, the speaker was unable to make it and the secretary suggested a quick group consensus about playing this recording at the meeting thinking it would make a good discussion topic. As it turned out it did. I did notice the part where Barry plays a recording of Bill W speaking on the 3rd tradition was muddy so I went back at it and managed to improve Bills audio quality enough I thought it worth a new upload. Barry L sober in 1945, speaking about the origin of the 3rd tradition at the 50th World Conference in Montreal in July 1985. He was (arguably) the first openly gay member of AA.  Tradition 3 - The only requirement for A.A. membership is a desire to stop drinking. Barry passed away 3 weeks after this speak. Barry is the author of the book Living Sober and was a great friend of Bill W and his wife Lois. In 1978 Lois gave the original manuscript of the big book to Barry, and in 1979 Barry signed a notarized letter gifting the manuscript to A.A. World Services. In exchange, he asked only to be able to keep it in his possession until his death. Somewhere between 1979 and Barry's death in 1985, everyone at A.A. World Services apparently forgot about this arrangement. The whereabouts of the manuscript remained unknown until it reappeared at an auction house in 2004, sold by a “Joseph B.” for $1.5 million. It was auctioned again in 2007 to Alabama resident Ken Roberts for $992,000.  A few months later, according to court documents, A.A. World Services rediscovered Barry's notarized letter and tried to legally regain possession, they failed. In 2018 the manuscript was once again auctioned off, this time for $2.4 million. Support Sober Cast: https://sobercast.com/donate Email: sobercast@gmail.com Sober Cast has 2900+ episodes available, visit SoberCast.com to access all the episodes where you can easily find topics or specific speakers using tags or search. https://sobercast.com

Join us for an incredible opportunity to engage with influential voices shaping our community! We are excited to welcome Mayor Johnny Ford, the esteemed founder of the World Conference of Mayors and the National Council of Black Mayors. He will be sharing valuable insights on Historic Black Settlements and his experiences as the former mayor of Tuskegee. Before Mayor Ford takes the stage, you'll hear from Professor Tyrene Wright, who will delve into her groundbreaking book, *Booker T. Washington and Africa: The Making of a Pan-Africanist*. Plus, Dr. Kelchi Egwin, Executive Director of Appeal Incorporated, will update us on the vital work of his organization. And don’t miss Pam Africa from MOVE, who will address the important issue of political prisoner Mumia Abu-Jamal.See omnystudio.com/listener for privacy information.

Join host Robin Linkhart as she speaks with Glenn Johnson, Peace and Justice Minister, about the 2025 Community of Christ World Conference. Glenn shares insights on the historic ordination of Stassi Cramm as President-Prophet and other historic leadership changes that led to increased diversity in church roles.  He also discusses his personal journey, including advocating for LGBTQIA+ inclusion within the church, and shares details about his current peace and justice ministries, such as his "100 days of exhortation and prayer" and the development of new resources. Learn more about Redwoods Peace Colloquy 2025Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

Not everyone agrees there is a climate emergency, but agree or not, we are seeing the results of global climate change, and those most affected are “the least of these.” At Community of Christ's 2025 World Conference, there was strong support for resolutions that seek to address climate issues, and three resolutions passed with significant support. In this episode of Climate Brewing, host Susan Oxley sits down with previous guest and climate enthusiast Paul Bethel to get his response to the actions taken at that conference. Listen in for some eye-opening information that shows how the realization of the Church's initiatives depends on our response... not just in legislation, but in real-life action. Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

Community of Christ's 2025 World Conference passed the G-10 resolution, entitled “Earth Stewardship Affirmation.” While some question the need for such a resolution, there is no doubt that the call for accountability was heard and supported.  The question remains whether or not the “support” will manifest itself in necessary action. Join host, Susan Oxley, as she sits down with Rick Bunch, chair of Community of Christ's World Church Earth Stewardship Team and lifelong contributor to natural resource management, to talk about why the time for hesitation is past and the time for action is now!   Check out the free Earth Stewardship resources mentioned by Rick in this episode. Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

This year marks two significant milestones worth our attention and our celebration. While we've already spent time reflecting on the 500th anniversary of the Anabaptist movement, 2025 also marks the 100th anniversary of the Mennonite World Conference (MWC). Recently, leaders from around the globe gathered in Germany and Switzerland to commemorate both anniversaries, and this week, we get the inside scoop from two of our USMB representatives: Gertrud Geddert and Sebastian Mireles.In this episode, Gertrud and Sebastian help us reflect on where we've come from, how the global Church is growing, and what it looks like to follow Jesus together across languages, cultures, and continents. Their stories and insights remind us why global connection matters and how honoring our past can strengthen our faith for today and the future.

The Divine presence is not limited to our spatial confines. At the recent Community of Christ World Conference, technology provided opportunity for the community to experience that first-hand as we gathered in places around the globe to share in worship, fellowship and legislative sessions. In all the places we gathered, the Spirit was present in abundance. Listen in to hear Presidents of Seventy, Karin Peter and Larry McGuire reflect on the experiences of sacred community and Divine presence in Côte d'Ivoire (Ivory Coast). Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

Community of Christ's 2025 World Conference has come and gone, but the excitement and challenge felt by those gathered has not yet waned. In the quiet moments after the “storm” of Conference, newly ordained Apostle, Matt Frizzell, sat in his new office reflecting on what had taken place and what it meant for him ... and for us ... as we move into the future. In this special episode of What's Brewing, Matt asks us to dream with him.  Imagine what we can accomplish in this world if we first choose to dream... and then make that dream a reality. Find the original blog post here.Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

Hope is here! For this special What's Brewing episode, we join the Thursday night First Presidency Worship of the 2025 Community of Christ World Conference, where we hear a message of hope in celebration of all that has taken place in the days leading up to this worship as well as the call into the future.  You'll hear the inspiring words from the newly ordained First Presidency and other leaders as they lead us into hope-filled action. Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

“It's easy to throw up our hands and say it's bigger than what we can do,” says this "Say What?!" episode's guest, Rick Bunch.  Join hosts Mary Anne and Kassie for a close look at G-10, the resolution submitted by the Community of Christ Earth Stewardship team for consideration at the 2025 World Conference. In this episode, Rick Bunch provides a little more background for the resolution as well as a number of practical ways to live out those things to which the resolution calls the Community of Christ ... a people who claim to hold a belief in the Sacredness of Creation. Check out the Earth Stewardship Lesson Series mentioned by Rick.Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

In this episode, we're joined by our 2025 Shark Tank competition winners: Molly Passow and Katherine Foerg from Niagara University. Their entry, Schedule Genie, uses Artificial Intelligence to assist in schedule coordination and management. You can view their whole presentation at World Conference (along with the other finalists' presentations) on CMAA's YouTube: https://www.youtube.com/watch?v=PYkor-0fuvM

Diverse, inclusive, multi-cultural, multi-lingual, spiritual, joyful, contemplative. Who knew worship could be all these things and more? In this episode of Say What?, hosts Mary Anne and Kassie sit down with Tyler Marz to talk about all of the ins and outs of worship at World Conference. Here, we get a behind-the-scenes look at what it takes to make worship happen in an intentionally inclusive way ... creating a meaningful experience for those gathered in person as well as those watching from across the globe. It's a huge and extremely complex task, but it will be such a blessing to so many. Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

The spotlight is back on at Graceland University, and this time it's shining on freshman and academic honors scholarship winner, Callie Dennis. Callie hails from the Liberty Street congregation in Independence, MO, and she has her eyes fixed on the goal.  That said, she's taking time to enjoy the Graceland experience and make it her own.  Join hosts Aliyah Farrell and Mike Hoffman as they sit down with Callie to get to know what makes her tick and find out her hopes for the church as we approach a historical World Conference. Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.

The word Zion has been an integral part of Community of Christ's journey as a people, but now it is being used by others in ways that are confusing and contradictory. In this episode of Say What?, host Mary Anne and Kassie sit down with Steve Kellogg, member of the Community of Christ Peace and Justice Team, and author of 2025 World Conference Resolution G-2.  Listen in to see what the Peace and Justice Team hopes to accomplish with this resolution, and get the added treat of hearing about Steve's personal journey toward peace and justice advocacy. Download TranscriptThanks for listening to Project Zion Podcast!Follow us on Facebook and Instagram!Intro and Outro music used with permission: “For Everyone Born,” Community of Christ Sings #285. Music © 2006 Brian Mann, admin. General Board of Global Ministries t/a GBGMusik, 458 Ponce de Leon Avenue, Atlanta, GA 30308. copyright@umcmission.org “The Trees of the Field,” Community of Christ Sings # 645, Music © 1975 Stuart Dauerman, Lillenas Publishing Company (admin. Music Services). All music for this episode was performed by Dr. Jan Kraybill, and produced by Chad Godfrey. NOTE: The series that make up the Project Zion Podcast explore the unique spiritual and theological gifts Community of Christ offers for today's world. Although Project Zion Podcast is a Ministry of Community of Christ. The views and opinions expressed in this episode are those speaking and do not necessarily reflect the official policy or position of Community of Christ.