The Rounds Table

Send us a textWelcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. David Juurlink, pharmacologist and internist, Professor of Medicine at the University of Toronto, and head of the Clinical Pharmacology and Toxicology division at Sunnybrook Health Sciences Centre, to chat about the top drug interactions you might be missing. Here we go!Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back, Rounds Table Listeners! This week we have a solo episode with Dr. John Fralick, discussing a recently published trial of the GLP-1 receptor agonist semaglutide for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). Here we go!Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis (0:00 – 6:33).The Good Stuff:Go Leafs go!Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the safety and efficacy of lorundrostat (an aldosterone synthase inhibitor) in treatment of uncontrolled and treatment-resistant hypertension. Here we go!Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension (0:00 – 7:02).The Good Stuff:Trial Files, a free monthly newsletter on practice-changing trials, delivered straight to your inbox. (7:03 - 7:50)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast. This week, Dr. Mike Fralick and special guest Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration discuss two recent papers: the use of brensocatib (a DPP-1 inhibitor) to treat bronchiectasis, and the effect of alteplase administered 4.5 to 24 hours after stroke in patients with mild posterior circulation stroke who did not receive thrombectomy. Two papers, here we go!Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis (0:00 – 12:46)Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours (12:47 – 24:55)And for the Good Stuff (24:56 – 26:08):Medicine Pods qMonthly newsletter Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Clinical Practice Guidelines series. This week, Drs. Mike and John Fralick discuss the 2025 ACC/AHA Clinical Practice Guidelines for Acute Coronary Syndrome. Here we go!2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes (0:00 - 18:56)Mike's interview with Dr. Jeff Carson:Episode 110 - Restrictive versus Liberal Transfusion in Myocardial Infarction with Dr. Jeff CarsonThe Good Stuff:Egg cracking tips! (18:57 - 19:47)Jerro (19:48 - 20:47)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of tirzepatide in weight reduction and diabetes prevention in persons with obesity. Here we go!Tirzepatide for Obesity Treatment and Diabetes Prevention (0:00 – 10:24).The Good Stuff:We've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here! (10:25 - 11:23)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining liberal fluid intake vs. fluid restriction in chronic heart failure. Here we go!Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial (0:00 – 4:20).And for the Good Stuff:starpowerdrummer on YouTube (4:21 – 5:20).Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of high-dose Vitamin D therapy in reducing disease activity in patients with clinically isolated syndrome (CIS) typical of multiple sclerosis (MS). Here we go!High-Dose Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis: The D-Lay MS Trial (0:00 – 7:35).Announcements (7:36 – 9:15):Canadian physicians, 2025 CMPA Council elections are underway in Alberta and Ontario! View the candidates and cast your ballot here.Check out Dr. Yatin Chada's podcast, beyondMD!And we've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here!Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss top papers from the 2025  American College of Cardiology (ACC) Annual Scientific Session. Hot off the presses, here we go!Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism (0:00 - 5:55)Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation (DapaTAVI) (5:56 - 9:51)Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes (9:52 - 14:04)Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE) (14:05 - 18:36)The Good Stuff:The Studio TV series on Apple (18:37 - 19:11)Cardiology Trial Files (19:12 - 20:40)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Dr. John Fralick and guest host Dr. Chunpeng Nie discuss two recent papers: resmetirom for the treatment of Nonalcoholic Steatohepatitis (NASH)—now known as Metabolic Dysfunction-Associated Steatohepatitis (MASH)—with liver fibrosis, and the effect of a Mediterranean diet on disease activity, inflammation, and the gut microbiome in patients with ulcerative colitis. Two papers, here we go!A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis (0:00 – 10:17)A Mediterranean Diet Pattern Improves Intestinal Inflammation Concomitant with Reshaping of the Bacteriome in Ulcerative Colitis: A Randomised Controlled Trial (10:18– 15:45)And for the Good Stuff:Shoutout to all the MTU teams supporting their R1's! (15:46 – 16:20).For the 1st time in Canada, surgeons put teeth in patients' eyes to restore sight (16:21 – 17:56)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Send us a textWelcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2023:Hydrocortisone in Severe Community-Acquired Pneumonia (0:00 – 5:39).Tirzepatide vs Insulin Lispro Added to Basal Insulin in Type 2 Diabetes (5:40 – 8:48).Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (8:49 – 12:29).Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection (12:30 – 17:49).Early versus Later Anticoagulation for Stroke with Atrial Fibrillation (17:50 – 23:38).And for the Good Stuff:The Beckham docuseries on Netflix (23:39 – 24:15)Upside Drinks (24:16 – 26:04).Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Jeffrey Carson, Distinguished Professor of Medicine at the Rutgers Robert Wood Johnson Medical School and Provost at Rutgers University, to chat about his recent publication - Restrictive versus Liberal Transfusion in Myocardial Infarction — A Patient-Level Meta-Analysis. Here we go!Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss two recent papers examining the effect of glucagon-like peptide-1 receptor agonists (GLP1's) on patients living with Parkinson's disease. Two papers, here we go!Trial of Lixisenatide in Early Parkinson's Disease (0:00 – 10:24).Exenatide once a week versus placebo as a potential disease-modifying treatment for people with Parkinson's disease (10:25 – 17:40).And for the Good Stuff:Port Blandford artist creates portraits from Scotch tape (17:41 – 18:33).Rheumatology for the Royal College podcast (18:34 – 19:42).This episode is sponsored by Northern Ontario Resident Streamlined Training and Reimbursement Program (NORSTAR). Check out details here!Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he will discuss a paper exploring endovascular treatment (EVT) for acute ischemic stroke due to medium-vessel occlusion. Here we go!Endovascular Treatment of Stroke Due to Medium-Vessel Occlusion (0:00 – 6:02).This episode is sponsored by Northern Ontario Resident Streamlined Training and Reimbursement Program (NORSTAR). Check out details here!Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike and John Fralick discuss two recent papers - the role of continuous glucose monitoring for diabetes management in hospital and the benefit of tirzepatide in patients with heart failure with preserved ejection fraction and obesity. Two papers, here we go!Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity (0:00 – 11:26).DIATEC: A Randomized Controlled Trial (11:26 – 19:56).And for the Good Stuff:Surgeons successfully transplant genetically edited pig kidney into U.S. man (19:56 – 20:55).Diabetes Trial Files (20:55 – 22:25)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Amy Yu, a Stroke Neurologist, Clinician-Scientist, and Associate Professor of Medicine at the University of Toronto and Sunnybrook Hospital, to chat about her hot-off-the press publication - Population-Level Screening for Diabetes and Dyslipidemia After Pregnancies Complicated by Hypertension or Diabetes!Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with a solo episode with Dr. Mike Fralick!This week, he will discuss a paper exploring the role of intravenous thrombolytic therapy in patients with minor ischemic stroke and intracranial vessel occlusion. Here we go!Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open-label, phase 3 superiority trial (0:00 – 6:18).And for the Good Stuff:Trial Files (6:18 – 7:59).Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePodsDo you ever feel like you can't get ahead of charting? Freed AI has an AI driven scribe for you! You can try Freed for free right now by going to getfreed.ai. Listeners can use the INTERN50 code for $50 off their first month!

Welcome back Rounds Table Listeners!We are back today with a solo episode with Dr. John Fralick!This week, he will discuss a paper exploring infliximab versus cyclophosphamide for the treatment of severe Behçet's Syndrome. Here we go!Infliximab versus Cyclophosphamide for Severe Behçet's Syndrome (0:00 – 5:15).And for the Good Stuff:Bob Ross and Painting (5:15 – 6:28).Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePodsDo you ever feel like you can't get ahead of charting? Freed AI has an AI driven scribe for you! You can try Freed for free right now by going to getfreed.ai. Listeners can use the INTERN50 code for $50 off their first month!

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike and John Fralick discuss two recent papers - whether aspirin should be held in patients with stable coronary artery disease and drug-eluting stents and the role of semaglutide in patients with obesity and knee osteoarthritis. Two papers, here we go!Aspirin Monotherapy vs. No Antiplatelet Therapy in Stable Patients With Coronary Stents Undergoing Low-to-Intermediate Risk Noncardiac Surgery (0:00 – 10:15).Once-Weekly Semaglutide in Persons with Obesity and Knee Osteoarthritis (10:15 – 22:50).And for the Good Stuff:"I'm making money from my terrible paintings" (22:50 – 23:25).Squid Game Season Two (23:25 – 24:43)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration, discuss two recent papers exploring oxygenation in acute respiratory failure and the use of ablation versus anti-arrhythmic medication for ventricular tachycardia. Two papers, here we go!High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients with Acute Respiratory Failure: The RENOVATE Randomized Clinical Trial (0:00 – 14:45).Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia (14:45 – 22:55).And for the Good Stuff:Medicine Pods! (22:55 – 23:51).Sign-up to our mailing list to receive link to attend the Royal College Epidemiology Crash Course hosted by Dr. Mike FralickQuestions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Dr. John Fralick sits down with Dr. Nicole Hawe, a first-year Internal Medicine resident at the University of British Columbia, to discuss her third place winning clinical vignette from the Canadian Society of Internal Medicine Annual Meeting 2024. Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Dr. Laiya Carayannopoulos sits down with Nick Sanchez (MD student) to discuss his second place winning clinical vignette from the Canadian Society of Internal Medicine Annual Meeting 2024. Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with a solo episode with Dr. John Fralick!This week, he will discuss a paper exploring whether Renin-Angiotensin System Inhibitors should be held before major non-cardiac surgery. Here we go!Continuation versus Discontinuation of Renin-Angiotensin System Inhibitors Before Major Non-Cardiac Surgery: The Stop-or-Not Randomized Clinical Trial (0:00 – 6:16).And for the Good Stuff:"Tweetorials" by Tony Breu (6:16 – 7:11).Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Dr. Zahra Merali (Host) sits down with Dr. Shaima Kaka (Internal Medicine resident) to discuss her first place winning clinical vignette (oral case report) from the Canadian Conference of Medicine Annual Meeting 2024.Resources: Diabetic Striatopathy: An Updated OverviewQuestions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. David-Dan Nguyen, a Urology Resident at the University of Toronto, to chat about his recent study, "Payments by Drug and Medical Device Manufacturers to US Peer Reviewers of Major Medical Journals", that has been recently published in JAMA.Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Happy Holidays Rounds Table Listeners! For our penultimate episode of 2024, we are back with a special treat! This week, Drs. Mike and John Fralick chat about the top five RCTs published over the past year:Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (0:00 – 3:40).Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (3:40 – 9:00).Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (9:00 – 13:55).Tirzepatide for Metabolic-Dysfunction Associated Steatohepatitis with Liver Fibrosis (13:55 – 20:00).Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (the Balance Trial) (20:00 – 23:30).And for the Good Stuff:Toronto Star Santa Claus Fund, Calgary Food Bank, Epilepsy Canada (23:30 – 24:51).Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Kevin Venus, a General Internist at Toronto Western Hospital, to chat about perioperative medicine!Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Justin Boyle and Emily Hughes discuss two recent papers - the effect of dietary sodium on blood pressure and the role of decolonization in nursing homes to prevent infection. Two papers, here we go!Effect of Dietary Sodium on Blood Pressure (0:00 – 10:05).Decolonization in Nursing Homes to Prevent Infection and Hospitalization (10:05 – 20:45).And for the Good Stuff:What Do Trainees Want? The Rise of House Staff Unions (20:45 – 22:48).Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario (22:48 – 24:39)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike and John Fralick discuss two recent papers - the Balance Trial and the role of inhaled amikacin in preventing VAP. Two papers, here we go!Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia (0:00 – 8:24).Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections (the Balance Trial) (8:24 – 17:24).And for the Good Stuff:The Tragically Hip: No Dress Rehearsal (17:24 – 18:30).www.powercalc.ca (18:30 – 20:06)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike Fralick and Justin Boyle discuss two recent papers exploring the effect of sitting time reduction on blood pressure and the discontinuation of RAAS inhibition perioperatively. Two papers, here we go!Sitting Time Reduction and Blood Pressure in Older Adults (0:00 – 11:35).Discontinuation versus continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial (11:35 – 21:32).And for the Good Stuff:Summer McIntosh becomes 1st Canadian to win 3 gold medals at a single Olympic Games (21:32 – 22:37).One-Pagers for the Wards by Dr. Mike Fralick! (22:37 – 24:13)Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with a special Rapid Fire Podcast!This week, Drs. Mike Fralick and Justin Boyle discuss top papers from the 2024 European of Society of Cardiology Congress. Here we go!Edoxaban Antithrombotic Therapy for Atrial Fibrillation and Stable Coronary Artery Disease (0:00 – 9:25).Beta-Blocker Interruption or Continuation after Myocardial Infarction (9:25 – 13:52).Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (13:52 – 21:20).Continuation vs. Discontinuation of Renin-Angiotensin System Inhibitors Before Major Non-Cardiac Surgery (21:20 – 28:51).Of note, for prescribers in Ontario, there is now a limited use code for finerenone for patients that have both T2DM and CKD. Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Take a listen to our live recording of The Canadian Conference of Internal Medicine Top papers of the year 2024 session! We talk about recent studies involving alzheimer's dementia, community acquired pneumonia, atrial fibrillation, MASLD and long covid. Host: Dr. Zahra Merali, Expert: Dr. Rajender Hanmiah. Check out www.medicinepods.com for a live video recording. You can also see a link to each paper there. Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Up to 30% of all healthcare offers no clinical value to patients. Reducing this care has the co-benefit of decreasing healthcare's carbon footprint. In this special CSIM episode, host Dr. Zahra Merali sits down with guests Dr. Billy Silverstein @WKSilverstein (General Internist, University of Toronto) and Dr. Owen Luv @OwenLuo5 (Internal Medicine Resident, McGill University) to discuss 4 of the Choosing Wisely Canada's climate-conscious recommendations (https://choosingwiselycanada.org/climate/).  They were integral in creating these recommendations, and have a wealth of practical tips about how we can implement them into our own practice! Infographic by Julia Simone (medical student). If you have not heard Part 1 - make sure to go back and listen to other Canada-wide experts in this area.Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome to Part 3 of a special series Medicine Pods has created in collaboration with the Canadian Society of Internal Medicine (CSIM)!In the lead up to the CSIM Conference, we will be discussing the runners up for the ever popular 'Top Papers' session. This year's session will be chaired by Dr. Raj Hanmiah, who has kindly joined us as a special guest for this series. If you want to find out which papers made the final cut, make sure to join us at the 'Top Papers' session on October 17th, where we will be recording live! Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

There are everyday practices we can stop or reduce that don't add value to patient care and harm the environment. In this special CSIM episode, host Dr. Zahra Merali sits down with guests Dr. Mathilde Gaudreau @MathildeGSimard (General Internist, University of Ottawa), Dr. Nabha Shetty (General Internist, Dalhousie University) and Dr. Valeria Stoynova (General Internist, Island Health/UBC Island Medical Program) to discuss 4 of the Choosing Wisely Canada's climate-conscious recommendations (https://choosingwiselycanada.org/climate/).  They were integral in creating these recommendations, and have a wealth of practical tips about how we can implement them into our own practice! Infographic by Julia Simone (medical student). Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome to Part 2 of a special series Medicine Pods has created in collaboration with the Canadian Society of Internal Medicine (CSIM)!In the lead up to the CSIM Conference, we will be discussing the runners up for the ever popular 'Top Papers' session. This year's session will be chaired by Dr. Raj Hanmiah, who has kindly joined us as a special guest for this series. If you want to find out which papers made the final cut, make sure to join us at the 'Top Papers' session on October 17th, where we will be recording live! Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome to a special series Medicine Pods has created in collaboration with the Canadian Society of Internal Medicine (CSIM)!In the lead up to the CSIM Conference, we will be discussing the runners up for the ever popular 'Top Papers' session. This year's session will be chaired by Dr. Raj Hanmiah, who has kindly joined us as a special guest for this series. If you want to find out which papers made the final cut, make sure to join us at the 'Top Papers' session on October 17th, where we will be there recording live! Questions? Comments? Feedback? We'd love to hear from you! @roundstable @InternAtWork @MedicinePods

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our new Medicine Pods collaboration, discuss two recent papers exploring the novel management of two rare diseases - ATTR Amyloidosis and Hereditary Angioedema. Two papers, here we go!Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis (0:00 – 14:15).Efficacy and Safety of Donidalorsen for Hereditary Angioedema (14:15 – 25:14).And for the Good Stuff:Medicine Pods! (25:14 – 26:23).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome to Medicine Pods! Your one stop shop for everything internal medicine, prn. Find us at www.medicinepods.com to find everything from The Intern at Work, The Rounds Table, Everything You Need To Know and Trial Files all in one place.

Welcome back Rounds Table Listeners!We are back this week with a special podcast episode! Dr. Mike Fralick sits down with Dr. Dirk von Lewinski, an Interventional Cardiologist, Intensivist, and Scientist from the Medical University of Graz, to chat about his practicing changing trial!Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike and John Fralick discuss two recent papers exploring the role of acupressure in pain management for knee osteroarthritis and the utility of AI-enabled electrocardiography. Two papers, here we go!Self-Administered Acupressure for Probable Knee Osteoarthritis in Middle-Aged and Older Adults (0:00 – 09:02).AI-enabled electrocardiography alert intervention and all-cause mortality: a pragmatic randomized clinical trial (09:02 – 23:16).And for the Good Stuff:100-year-old veteran parachutes out of a plane, raising over $100K for SickKids hospital (23:16 – 23:50).One-Pagers for the Wards (23:50 – 25:15).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. John Fralick and Justin Boyle discuss two recent papers exploring the role of semaglutide in CKD in patients with Type II Diabetes and the utility of tirzepatide in metabolic dysfunction-associated steatohepatitis with liver fibrosis. Two papers, here we go!Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (0:00 – 09:32).Tirzepatide for Metabolic Dysfunction-Associated Steatohepatitis with Liver Fibrosis (09:32 – 17:06).And for the Good Stuff:Congratulations to everyone starting/progressing through residency/finishing their training! (17:06 – 17:43).Calgary officials aiming for 'low end' of repair timeline after pipes arrive from San Diego (17:43 – 19:06).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!In this throwback episode, Drs. John Fralick and Justin Boyle discuss early versus late anticoagulation after stroke with atrial fibrillation and dual antiplatelet therapy versus alteplase in minor ischemic stroke.Early versus Later Anticoagulation for Stroke with Atrial Fibrillation (0:00 – 8:48).Dual Antiplatelet Therapy vs Alteplase for PatientsWith Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial (8:48 – 16:20).And for the Good Stuff:Taylor Swift makes history with more No. 1 albums than any female artist (16:20 – 17:03).‘I finally did it': Ottawa's Michael Woods wins 9th stage of Tour de France (17:03 – 18:00).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!In this throwback episode, Drs. Mike and John Fralick discuss the use of semaglutide in patients with obesity without diabetes and changes in renal function after starting dapagliflozin in patients with heart failure. Check it out below!Decline in Estimated Glomerular Filtration Rate After Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Secondary Analysis of the DELIVER Randomized Clinical Trial (0:00 – 09:40).Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (09:40 – 19:24).And for the Good Stuff:How Ozempic and Weight Loss Drugs Are Reshaping Denmark's Economy (19:24 – 19:58).How a Canadian scientist and a venomous lizard helped pave the way for Ozempic (19:58 – 23:36).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!We are back today with a solo episode with Dr. Mike Fralick!This week, he will discuss a recent paper exploring the efficacy of tirzepatide in treating obstructive sleep apnea and obesity. Here we go!Tirzepatide for the Treatment of Obstructive Sleep Apnea and ObesityCheck out the New Motto!Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!We are back today with a solo episode with Dr. John Fralick!This week, he will discuss a paper exploring a modification of the Valsalva manoeuvre for the treatment of supraventricular tachycardias. Here we go!Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT) (0:00 – 7:00).And for the Good Stuff: Live Transcribe (7:00 – 8:16).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!In this throwback episode, Drs. Mike Fralick and Justin Boyle discuss two papers exploring intravenous iron infusions in heart failure with iron deficiency and in reducing blood transfusion requirements in patients with hip fracture. Check it out below!Ferric Carboxymaltose in Heart Failure with Iron Deficiency (0:00 – 8:12).Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial) (8:12 – 19:00).And for the Good Stuff:Pop Culture Nostalgia (19:00 – 19:33).Thrombo Trial Files (19:33 – 20:48).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike and John Fralick discuss two recent papers exploring the role of ticagrelor with aspirin versus ticagrelor alone after percutaneous coronary intervention in acute MI and the efficacy of empagliflozin after acute MI. Two papers, here we go!Ticagrelor alone versus ticagrelor plus aspirin from month 1 to month 12 after percutaneous coronary intervention in patients with acute coronary syndromes (ULTIMATE-DAPT) (0:00 – 9:22). Empagliflozin after Acute Myocardial Infarction (9:22 – 16:00).And for the Good Stuff:Impact of presentation at conference with timed release of academic publication (16:00 – 17:32).Top spot in the PWHL and attendance record at stake in latest Montreal-Toronto showdown (17:32 – 19:59).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!In this throwback episode, Drs. John and Mike Fralick discuss two papers – one, exploring IVIG in the treatment of dermatomyositis, and the second investigating the effect of tranexamic acid in patients with acute gastrointestinal bleeding.Trial of Intravenous Immune Globulin in Dermatomyositis (0:00 – 8:38).Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international, randomised, double-blind, placebo-controlled trial (8:38 – 18:04).And for the Good Stuff:Alberta using humour to attract workers (18:04 – 18:50).CBME in Residency Education (18:50 – 21:02).Questions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Drs. Mike Fralick and Emily Hughes discuss two recent papers exploring the role of beta blockers after myocardial infarction when there is preserved ejection fraction and the utility of Paxlovid in vaccinated versus unvaccinated adult outpatients with symptomatic COVID-19. Two papers, here we go!Nirmatrelvir for Vaccinated or Unvaccinated Adult Outpatients with COVID-19 (0:00 – 14:02). Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction (14:02 – 27:24).And for the Good Stuff: A 65-Year-Old Woman with an Incorrect Operation on the Left Hand (27:24 – 31:04).Bradycardia associated with remdesivir therapy for COVID-19 in a 59-year-old manQuestions? Comments? Feedback? We'd love to hear from you! @roundstable

Welcome back Rounds Table Listeners!We are back today with our Classic Rapid Fire Podcast!This week, Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast, discuss two recent papers exploring the role tenecteplase between 4.5 and 24 hours in ischemic stroke and comparing fidaxomicin with vancomycin in treating C. difficile when patients are receiving concurrent antibiotics. Two papers, here we go!Tenecteplase for Stroke at 4.5 to 24 Hours with Perfusion-Imaging Selection (0:00 – 15:20).Comparing Fidaxomicin with Oral Vancomycin for the Treatment of C. difficile Infection in Hospitalized Patients Receiving Concomitant Antibiotics for Concurrent Infections (15:20 – 28:58).Questions? Comments? Feedback? We'd love to hear from you! @roundstable