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Today, we're speaking to Dr Cini Bhanu, GP and Academic Clinical Lecturer in the Primary Care and Population Health Department at University College London. Title of paper: Antidepressants and risk of postural hypotension: a self-controlled case series study in UK primary careAvailable at: https://doi.org/10.3399/BJGP.2024.0429Antidepressants are associated with postural hypotension (PH). This is not widely recognised in general practice, where antihypertensives are considered the worst culprits. The present study examined >21 000 older adults and found a striking increased risk of PH with use of all antidepressants (over a four- fold risk with SSRIs) in the first 28 days of initiation. TranscriptThis transcript was generated using AI and has not been reviewed for accuracy. Please be aware it may contain errors or omissions.Speaker A00:00:00.480 - 00:00:56.990Hello and welcome to BJGP Interviews. My name is Nada Khan and I'm one of the associate editors of the bjgp. Thanks for listening to this podcast today.In today's episode, we're speaking to Dr. Cini Banu, who is a GP in an academic clinical lecturer based in the Department of Primary Care and Population Health at University College London.We're here to talk about her recent paper in the BJGP titled Antidepressants and Risk of Postural Hypertension, A Self Controlled Case Series Study in UK Primary Care. So, hi Cinny, it's really nice to meet you today.I guess this is an interesting area to cover, especially as the prescribing rates for some antidepressant medications are increasing.But I don't know what your feeling is, but I'm not sure if many GPs would actually know that antidepressants are associated with poison postural hypertension. So, yeah, talk us through that.Speaker B00:00:57.310 - 00:01:18.350Yeah, so I think that's one of the reasons this study is so important.So definitely from conversations that I've had with gps that I work with and it's not commonly recognized that postural hypotension is associated with antidepressants, though it is by geriatricians, for example, where it's very.Speaker A00:01:18.350 - 00:01:41.850Well recognized and in this study used a big database to look at the risk of new postural hypertension associated with the use of antidepressants in people aged over 60.I guess there's quite a lot of in depth stuff in the methods, but I guess just for a summary for people who are interested in what you did, do you mind just sort of going over it at sort of like a high level?Speaker B00:01:41.850 - 00:02:54.200Yeah, yeah. So we looked at a big database, what we call a routine primary care database called imrd.And essentially this captures data from software that gps use like EMIS and Vision System and captures a whole load of information like problems, symptoms and prescriptions. So we went into this database and identified everyone over the age of 60 that might be eligible during our study period.And for this we looked at people that were contributing at least one full year of data between 2010 and 2018. And then within that we identified people with a first diagnosis of postural hypotension.And then again we made subgroups according to people who had this diagnosis but also had a first prescription of a new antidepressant during that time.And what we were interested in, and the methodology is called a self controlled case series, we weren't interested in who got postural Hypotension, because everyone was a case, but rather...
Send us a textTreatment of Hypotension of Prematurity: a randomised trial.Alderliesten T, Arasteh E, van Alphen A, Groenendaal F, Dudink J, Benders MJ, van Bel F, Lemmers P.Arch Dis Child Fetal Neonatal Ed. 2025 May 24:fetalneonatal-2024-328253. doi: 10.1136/archdischild-2024-328253. Online ahead of print.PMID: 40413017As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
Spontaneous intracranial hypotension reflects a disruption of the normal continuous production, circulation, and reabsorption of CSF. Diagnosis requires the recognition of common and uncommon presentations, careful selection and scrutiny of brain and spine imaging, and, frequently, referral to specialist centers. In this episode, Gordon Smith, MD, FAAN speaks with Jill C. Rau, MD, PhD, author of the article “Clinical Features and Diagnosis of Spontaneous Intracranial Hypotension” in the Continuum® June 2025 Disorders of CSF Dynamics issue. Dr. Smith is a Continuum® Audio interviewer and a professor and chair of neurology at Kenneth and Dianne Wright Distinguished Chair in Clinical and Translational Research at Virginia Commonwealth University in Richmond, Virginia. Dr. Rau is an assistant professor of clinical neurology at the University of Arizona, School of Medicine-Phoenix in Phoenix, Arizona. Additional Resources Read the article: continuumjournal.com Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @gordonsmithMD Full episode transcript available here Interview with Jill Rau, MD Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Smith: This is Dr Gordon Smith. Today I'm interviewing Dr Jill Rau about her article on clinical features and diagnosis of spontaneous intracranial hypotension, which she wrote with Dr Jeremy Cutsworth-Gregory from the Mayo Clinic. This article appears in the 2025 Continuum issue on disorders of CSF dynamics. I'm really excited to welcome you to the Continuum podcast. Maybe you can start by just telling our listeners a little bit about yourself? Dr Rau: Hi, thanks for having me. I'm really honored to be here, and I really enjoyed writing the paper with Dr Cutsforth-Gregory. I hope you guys enjoy it. I am the director of headache medicine at the Baba Bay Neuroscience Institute at Honor Health in Scottsdale, Arizona. I'm also currently the chair of the special interest group in CSF Dynamics at the American Headache Society, and I've had a special interest in this field since I first watched Dr Linda Gray speak at a conference where she talked about spinal CSF leaks and their different presentations. And they were so different than what I had been taught in residency. They're not just the post-LP headache. They have such a wide variety of presentations and how devastating they can be, and how much impact there is on someone's life when you find it and fix it. And I've been super interested in the field and involved in research since that time. And, yeah. Love it. Dr Smith: Well, thanks for sharing your story. And as I reflected on our conversation ahead of time and have been thinking about this issue… this is a cool topic, and every time I read one of these manuscripts and have the opportunity to speak with one of the authors, I learn a ton, because this was something that wasn't even on the radar when I trained back in the 1800's. So, really looking forward to the conversation. I wonder if you could really briefly just summarize or remind for everyone the normal physiology about CSF dynamics, you know, production, absorption, and so forth? Dr Rau: So, the CSF is the fluid that surrounds the brain and the spinal cord, and it's contained by the dura, which is like a canvas or a sac that covers that whole brain and spinal cord. And within the ventricles of the brain, the choroid plexus produce CSF. It's constantly producing and then being reabsorbed by the arachnoid granulations and pushed into the venous space, the cerebral sinuses, venous sinuses. And also some absorption and push into the lymphatics that we've just learned about in the past year. This is kind of new data coming out, so always learning more and more about CSF, but we know that it bathes the brain and the spinal cord, helps keep some buoyancy of the brain as well as pushing nutrients in and pulling out metabolic waste. And it sort of keeps the brain in the state of homeostasis that's happy. And so, when there's a disruption of that flow and the amount of fluid there, that disrupts that, that can cause lots of different symptoms and problems for people. Dr Smith: One of the many new things I learned is that even the name of this---spontaneous intracranial hypotension---is misleading. And I think this is clinically relevant, as we'll probably get to in a moment, but can you talk a little bit about this? Is this really like a pressure disorder or a volume disorder? Dr Rau: Yeah. It's almost certainly a volume disorder. We do see in some people that they have low pressure, and it's still part of the diagnostic criteria. But it's there because if you have a low pressure, if you measure an opening pressure and it's below six, if you're measuring it in the spine in the right place, then you have indication that there's low volume. But there's over 50% of people's opening pressure who have a spinal CSF leak, have all the symptoms and can be fixed. So, they have normal pressure in 50% of the people. So, it is an inaccurate term, hypotension, but it was originally discovered because of the thought that it was a low-pressure situation. Some of the findings would suggest low pressure, but ultimately, we are pretty sure it's a low-volume condition. Dr Smith: Another new thing that I learned that really blew me away is how bad this can be. I did a podcast with Mark Burish about cluster, and I was reminded many cluster patients are pushed to the point of suicidal ideation or committing suicide by the severity of pain. And this sounds like for many patients it's equally severe. Can you maybe paint a picture for our listeners why this is so clinically important? Dr Rau: A large number of people, even people who are known to have leaks because they've had them before or they've releaked, they have a lot of brain fog and cognitive impairment. They often have severe headaches when they're upright. So, orthostatic headache is probably the number one most common symptom, and those headaches are one of the worst headaches out there. When people stand up, their fluid is not supporting the brain and there's an intense amount of pain. And so, they spend a large portion of their lives horizontal. And there's associated symptoms with that, it's not just headache pain and brain fog. There's neck pain. There's often subsequent disorders that accompany this, like partial orthostatic tachycardia syndrome. We don't know if that's because of deconditioning or an actual sequela of the disease, but it's a frequent comorbidity. We have patients that have extreme dizziness with their symptoms, but many patients are limited to hours, if that, upright per day, combined, total. And so they live their lives, often, just in the dark, lots of photophobia, sensitive to the light, really unable to function. It's also very hard to find and so underrecognized that a lot of patients, especially if they don't have that really clinical symptom of orthostatic headache. So, it's often missed. So, they're just debilitated. You know, treatments don't work because it's not a migraine and it's not a typical headache. It's a mechanical issue as well as a metabolic issue and not found, not a lot helps it. Dr Smith: So, you know, I have always thought about this as really primarily an orthostatic symptom. I wonder if you can talk about the complexity of this; in particular, kind of how this evolves over time, because it's not quite that simple. And maybe in doing so, you can give our listeners some pearls on when they should be thinking about this disorder? Dr Rau: A large portion of people do have headache with spinal CSF leak, in particular, spontaneous intracranial hypertension- hypotension, excuse me. And that's something to be thought about, is that there are spontaneous conditions where people have either rupture of the dural sac, or an erosion of the dural sac, or a development of a connection between the dura and the venous system. And that is taking away or allowing CSF to escape. In these instances that patients have spontaneous, there may be a different presentation than if they have, like, a postdural puncture or a chronic traumatic or iatrogenic leak. And we're not sure of that yet, but we're looking into that. Still, the largest presentation is headache, and orthostatic headache is very dominant in the headache realm. But over time, patients' brains can compensate for that lack of CSF and start overproducing---or at least we think that's probably what's happening. And you may see a reduction in the orthostatic symptoms over time, and you may see an improvement in the radiographic findings. So, there are some interesting papers that have been published that look at these changes over time, and we do see that sometimes within that first three to four months; this is the most common time to see that change. Other patients may worsen. You may actually see someone going from looking sort of normal radiographically to developing more of a SIH-type of picture on the brain. And so it's not predictable which patients have gone from orthostatic to improvement or the other way around, both radiographically and clinically. So, it can be quite difficult to tell. So, for me, if I have a patient that comes to me and they're struggling with headache… if it's orthostatic, very clearly orthostatic: I lay down, I get considerably better or my headache completely goes away. And then when I stand up, it comes on relatively quickly, within an hour. And sometimes it's a worsening-throughout-the-day type of thing, it's lowest in the morning and it worsens throughout the day. These are the times that it's most obvious to think about CSF leak. Especially if that headache onset relatively suddenly, if it onset after a small trauma. Like I've had patients that say, you know, I was doing yoga and I did some twists and I felt kind of a pop. And then I've had this headache that is horrible when I'm upright but is better when I lay down ever since, you know, since that time. That's kind of a very classic presentation of spinal CSF leak or spontaneous intracranial hypotension. Maybe a less common presentation would be someone who comes to you, they've had a persistent headache for a couple years, they kind of remember it started in March of a couple years ago, but they don't know. Maybe it's, you know, it's a little better when they lay down. It may be a little worse when they're up moving around, but so is migraine, and it's a migrainous headache. But they've tried every migraine drug you can think of. Nothing is responding, nothing helps. I'm always looking at patients who are new daily, persistent headaches and patients who aren't responding to meds even if it's not new daily, but they have just barely any response. I will always go back and examine their brain imaging and get full spine to make sure I'm not missing. And you can never be 100% sure, but it's always good to consider those patients to the best of your ability, if that- have that in the back of your mind. Dr Smith: So obviously, goes without saying, this is something people need to have on their radar and think about. And then we'll talk more about diagnostic tools here in a second. But how common is this? If you're a headache doc, you see a lot of patients who have intractable headaches. And how often do you see this in your headache practice? Now you're- this is your thing, so probably a little more than others, but, you know, how common will someone who sees a lot of headache encounter these patients? Dr Rau: If you see a lot of headache, I mean, currently the thought is it's about 5 in 100,000. That was from a study before we were finding CSF venous fistulas. I think a lot of us think it's more common than that, but it's not super common. We don't have good estimates, but I would guess between 5 and 10 for 100,000 persons, not “persons who come to a tertiary headache clinic with intractable headaches”. So, it's hard to gauge how frequent it is, but I would say it's considerably more frequent than we currently think it is. There's still a group of people with orthostatic headaches that we can't find leaks on; that, once you treat other things that can cause or look for other things that can cause orthostatic headaches. So, there may be even still a pathophysiology out there that is still a leak type. Before 2014, we didn't even know about CSF venous fistulas. And now here we are; like, 50% of them are CSF venous fistulas. So, you know, we're still in a huge learning curve right now. Dr Smith: So, I definitely want to talk about the fistulas in a second. But before moving on, one of the things that I found really interesting is the wide spectrum of clinical phenotype. And we obviously don't have a lot of time to get into all of these different ones, but the one that I was hoping you might talk about---and there's a really great case, and you're on bunch of great case, a great case of this---is brain sagging dementia, not a term I've used before. Can you really briefly just tell our listeners about that, because that's a really interesting story and a great case in your article? Dr Rau: Yeah. So, brain sag dementia is a… almost like an extreme version of a spontaneous intracranial hypotension. Where there is clear brain sag in the imaging---so that's helpful---but the patients present kind of like a frontotemporal dementia. And when this was first started to being determined, you could turn the patient into Trendelenburg, and sometimes they would improve. There are some practitioners that have introduced fluid into the thecal sac and had temporary improvement. Patching has improvement, then they leak again, sometimes not. But the clinical changes with this have been pretty tremendous to be able to identify that that's a real thing. And in some cases, out of Cedars Sinai, you know, who does a lot of the best research in this, they've had lots of cases where they can't find the leak, but there's clear brain sag that fits with our clinical picture of CSF leaks. So, we're on a learning curve. But yeah, this- they really present. They have disinhibition and cognitive impairment that is very similar to frontotemporal dementia. Dr Smith: Well, so let's talk about what causes this. You mentioned CSF venous fistulas. I mean, that was reported now just over a decade ago, it's pretty amazing. That accounts for about half of cases, if I understand correctly. What are the other causes? And then we'll talk more about therapy in a minute, but what causes this? Dr Rau: So, within the realm of spontaneous, you know, we say it's spontaneous. But the spontaneous cases we account for, they can be tears in the dura, which are usually sort of lateral tears in the dura. They can be little places that rubbed a hole, often on an osteophyte from the spine. They can come from these spinal diverticuli. So, I always describe it to my patients like those balls that have mesh and squishy, and you squeeze them in the- through the mesh, there's the extra little bubbling out. If you think of like the dura bubbling, out in some cases, through the framing of the spine, right where the spinal nerve roots come out, they should poke out like wires from the dura. But in many cases they poke out with this extra dura surrounding them, and we call that spinal diverticuli. And if you imagine like the weakening of where you squeeze that, you know, balloon through your fingers, in those locations, that's a very common place to find a CSF leak, and you can imagine that the integrity of the dura there may be less than it would be if it were not being expanded in that direction. And that's often the most common place we see these CSF venous fistulas. So, you can get minor traumas; like I said, it can be spontaneous, like someone just develops a leak one day. It can be rubbed off, and it can be a development of a connection between the dura and the venous system. There are also iatrogenic causes, but we don't consider them spontaneous. But when you're considering your patients for spontaneous cases, you should consider if they've ever had chronic---even long, long time ago---had any spinal implementation, procedures near the spine, spinal injections, LPs in the past, and especially women who've had epidurals in pregnancy. Dr Smith: All right, so we see a patient, positional severe headache, who meets the clinical criteria. Next step, MRI scan? Dr Rau: Yeah. So, the first thing is always to get the brain MRI with and without contrast. Most places will have a SIH or a spinal CSF leak protocol, but you should get contrast because one of the most pathognomonic findings on brain MRI is that smooth diffuse dural enhancement. And that's a really fantastic thing when you find it, because it's kind of a slam dunk. If you find it, then you will see other findings. It almost never exists alone. But if you see that, it's pretty much a spinal CSF leak. But you're also looking for subdural collections, any indication of brain sag. We do have these new algorithms that have come out in the past couple of years that are helpful. They're not exclusionary---you can have negative findings on the brain and still have spinal CSF leak---but the brain MRI is extremely helpful. If it's positive for the findings, it really does help you nudge you in the direction of further investigations and treatments. Dr Smith: And what about those further investigations and treatments, right? So, you see that there's findings consistent with low pressure, and I guess I should say low intracranial CSF volume. Be that as it may, what's the next step after that? Dr Rau: Depends on where you are and what you can do. I almost always will get a full spine MRI: so, C spine, T spine, and L spine separately. Not, you know, we don't want it all in one picture, because we want to get the full view. And you want to get that with at least T2 highly- heavily T2 weighted with fat saturation in at least the sagittal and axial planes. It's really helpful if you can get it in the coronal planes, but we have to have- often have good talks with your radiologist to get the coronal plane. I spoke about the spinal diverticuli earlier, and I want to clarify a little bit of something. The coronal image will show those really nicely. It's interesting, but 44% of people have those. So just having the spinal diverticuli does not indicate that you have a leak. But if you have a lot of those, there may be more likelihood of having leak than if you don't have any of those. So, I will get all of those and I will look at them myself, but I've been looking at them myself for a long time. But a lot of radiologists in community hospitals, especially not- nonneuroradiologists, but even neuroradiologists, this isn't something that's that everybody's been educated about, and we've been learning so much about it so rapidly in the past ten years. It's not easy to do and it's often missed. And if it's not protocoled properly, the fat saturation's not there, it's very hard to see… you can have a leak and not see it. Even the best people, like- it's not always something that's visible. And these CSF venous fistulas that we talked about are never visible on normal MRI imaging. Nonetheless, I will run those because if I can find a leak---and 90% of the ones that are found on MRI imaging are in the thoracic spine. So that's where I spend the most of my time looking. But if you find it, that's another thing to take to your team to say, hey, look, here it is, let's try and do this, or, let's try and do that, or, I've got more evidence. And there are other findings on the spine; not just the leak, but other findings, sometimes, you can see on spine that maybe help you push you towards, yes, this is probably a leak versus not. Dr Smith: So, your article has a lot of great examples and detail about kind of advanced imaging to, like, find the fistula and what not. I guess I'm thinking most of our listeners are probably practicing in a location where they don't have a team that really focuses on that. So, let's say we do the imaging of the spine and you don't find a clear cause. Is the next step to just do a blood patch? Do you send them to someone like you? What's the practical next step? Dr Rau: Yeah, if your- regardless of whether you find a leak or not, if your clinical acumen is such that you think this patient has a leak or I've treated them for everything else and it's not working and I have at least a high enough suspicion that I think the risk of getting a patch is lower than the benefit that if they got a patch and it worked, I do send my patients for non-directed blood patches, because it currently does take a long time to get them to a center that can do CT myelograms or any kind of advanced imaging to look for sort of a CSF venous fistula or to get treated outside of a nondirected patch. You know, sometimes nondirected patches are beneficial for patients, and there's some good papers out there that sort of explain the low risks of doing these if done properly versus the extreme benefit for patients when it works. And, I mean, I can't tell you how many people come in and tell me how their lives are changed because they finally got a blood patch. And sometimes it works. And it's life-changing for those people. You know, they go back to work. They can interact with their kids again. Before, they didn't know what was wrong, just had this headache that started. So it's worth doing if you have a strong clinical suspicion. Dr Smith: Yeah. I mean, that was great. And, you know, to go back to where we began, this is severe. It's something like 60% of patients with this problem have thought about suicide, right? And you take this patient and cure the problem. I feel really empowered having read the article and talked to you today. And so, I'm ready to go out and look for this. Thank you so much for a really engaging conversation. This has been terrific. Dr Rau: Thank you. I appreciate it. I enjoyed being here. Dr Smith: Again, today I've been interviewing Dr Jill Rau about her article on clinical features and diagnosis of spontaneous intracranial hypotension---which I guess I should say hypovolemia after having talked to you---which she wrote with Dr Jeremy Cutsworth-Gregory. This article appears in the most recent issue of Continuum on disorders of CSF dynamics. Please be sure to check out Continuum Audio episodes from this really interesting issue and other interesting issues. And thank you, our listeners, again for listening to us today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Irbesartan is an angiotensin II receptor blocker (ARB) used primarily for the management of hypertension and diabetic nephropathy in type 2 diabetes. It selectively inhibits the binding of angiotensin II to the AT1 receptor found in vascular smooth muscle and the adrenal gland. This blockade results in vasodilation, reduced aldosterone secretion, decreased sodium and water retention, and ultimately lower blood pressure. Irbesartan is administered orally, with a typical starting dose of 150 mg once daily, which may be increased to 300 mg depending on the patient's clinical response and tolerability. Adverse effects of irbesartan are generally mild but can include hyperkalemia and dizziness. Hypotension may occur, especially in volume-depleted individuals or those on diuretics. Routine monitoring of renal function and serum potassium is recommended, especially in patients with underlying kidney disease or those taking potassium-sparing agents or supplements. Irbesartan is contraindicated in pregnancy due to the risk of fetal toxicity and should be discontinued as soon as pregnancy is detected.
Dr. K explains what counts as low blood pressure, why it becomes common with aging, when it can be dangerous, and what to do about it. She also explains orthostatic hypotension, a common problem that affects many older adults and can lead to symptoms, such as dizziness or even falls.
Dr. Jessica Ailani and Dr. Kathleen Digre discuss the evolution of spontaneous intracranial hypotension (SIH) diagnosis and treatment over the past decade.
Dr. Jessica Ailani talks with Dr. Kathleen Digre about the evolution of spontaneous intracranial hypotension (SIH) diagnosis and treatment over the past decade. Disclosures can be found at Neurology.org.
In this Nephrology episode, Dr.Samira Farouk discusses the nuances of AKI, why you should be trending Urine like you trend Troponin. Stay tuned to find out the final diagnosis! Session facilitator: Dr.Elena Storz Case Discussants: Dr.Douglas Farrell MD: Nephrology Fellow, Icahn School of Medicine at Mount Sinai Dr. Samira Farouk MD: Associate Professor of Medicine… Read More »Episode 389: Rafael Medina Subspecialty Series – Hypotension and Peaked T waves
02/016/25The Healthy Matters PodcastS04_E09 - Hypertension: Avoiding the Silent KillerHigh Blood Pressure, or hypertension, is often called The Silent Killer because it can wreak havoc on our bodies, oftentimes without us even knowing. It's estimated that 85 million people in the U.S. alone have high blood pressure, which is an alarming stat, especially given that it can be a major contributor to a whole host of bad stuff - like stroke, heart attacks and kidney disease, to name just a few. But what causes hypertension? Why is it so damaging to our bodies? Who's most at risk, and what can be done to keep it in check?From Hypertension to Hypotension, on Episode 9 of our show, we're talking all things blood pressure with a repeat guest, Dr. Woubeshet Ayanew (MD). Dr. Ayenew is a cardiologist at Hennepin Healtcare and currently holds the record for most downloads of a single episode of our show (S3: Episode 09 - "Cholesterol: The Good, The Bad, and the Triglycerides...)! He'll break down the condition for us and explain the causes and effects of high blood pressure, best practices to stay ahead of it, the importance of home monitoring (and what those numbers actually mean), and what can be done for those looking to get things under control. This is a great chance to learn all about hypertension and get some useful tips on how to manage your blood pressure from a true expert. Join us!Links:American Heart AssociationHome Blood Pressure MonitoringWe're open to your comments or ideas for future shows!Email - healthymatters@hcmed.orgCall - 612-873-TALK (8255)Get a preview of upcoming shows on social media and find out more about our show at www.healthymatters.org.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode997. The post 997: The use of methylene blue for the treatment of refractory anaphylaxis without hypotension appeared first on Pharmacy Joe.
Hypotension has been mentioned repeatedly in literature, but is it really a thing. Link to full podcast: https://creators.spotify.com/pod/show/dennis3211/episodes/Prolonged-Field-Care-Podcast-212-TXA-e2sss55 Thank you to Delta Development Team for in part, sponsoring this podcast. deltadevteam.com For more content go to www.prolongedfieldcare.org Consider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
Does TXA cause hypotension or is it just correlated due to the types of trauma patients it's indicated for? Link to full podcast: https://creators.spotify.com/pod/show/dennis3211/episodes/Prolonged-Field-Care-Podcast-212-TXA-e2sss55
L'hypotension (tension trop basse) affecte de nombreuses personnes. Comment accompagner cette situation à l'aide des plantes médicinales ? ➜ www.altheaprovence.com/podcast-lettreinfo ---------------------------- La transcription du podcast : ➜ www.altheaprovence.com/hypotension-les-plantes-qui-peuvent-aider/
It's that time of year again. Let's finish the year off strong with your favorite podcasts. Don't worry...I already have new episodes in the pipe starting in January. In this episode of the PFC Podcast, Dennis and Jeff delve into the complexities of anoxic brain injury, discussing its causes, recovery processes, and prevention strategies in tactical environments. They emphasize the importance of monitoring, airway management, and resuscitation goals, while also addressing the management of hypotension and shock. The conversation highlights the significance of preventing secondary brain injuries and the role of basic medical practices in saving lives. Takeaways Anoxic brain injury is caused by a lack of oxygen to the brain. Recovery from brain injuries can take time and various therapies. Preventing blood loss is crucial in tactical environments. Monitoring oxygen saturation is essential for early detection. Airway management decisions should be based on the patient's condition. Resuscitation goals should focus on maintaining adequate blood pressure and oxygen levels. Hypotension can arise from various causes and needs to be managed effectively. Resuscitation targets should aim for optimal blood pressure and oxygen saturation. Preventing secondary brain injuries is critical for patient outcomes. Basic medical practices can significantly impact survival rates. Thank you to Delta Development Team for in part, sponsoring this podcast. deltadevteam.com For more content go to www.prolongedfieldcare.org Consider supporting us: patreon.com/ProlongedFieldCareCollective or www.lobocoffeeco.com/product-page/prolonged-field-care
Contributor: Aaron Lessen MD Educational Pearls: Induction agent selection during rapid sequence intubation involves accounting for hemodynamic stability in the post-intubation setting Many emergency departments use ketamine or etomidate A recent study sought to explore the rates of post-induction hypotension of ketamine compared with propofol Single center retrospective cohort study of patients between 2018-2021 Ketamine and propofol were both significantly associated with post-induction hypotension Ketamine adjusted odds ratio = 4.50 Propofol adjusted odds ratio = 4.88 50% of patients became hypotensive after induction with either propofol or ketamine These findings suggest post-induction hypotension is mainly due to sympatholysis rather than the choice of agent itself References Tamsett Z, Douglas N, King C, et al. Does the choice of induction agent in rapid sequence intubation in the emergency department influence the incidence of post-induction hypotension?. Emerg Med Australas. 2024;36(3):340-347. doi:10.1111/1742-6723.14355 Summarized & Edited by Jorge Chalit, OMS3 Donate: https://emergencymedicalminute.org/donate/
In this episode, researchers explore how asymptomatic versus symptomatic hypertension affects heart failure patients on sacubitril valsartan, finding that both types are linked to worse outcomes, but the drug's benefits remain strong, suggesting clinicians should avoid stopping treatment based solely on blood pressure.
Recorded at the recent American Association of Nurse Anesthesiology meeting this piece focuses upon the importance of addressing intraoperative hypotension (IOH) and its broader implications for patient outcomes, such as surgical site infections (SSI), postoperative cognitive dysfunction, and other complications. We also discuss the need for continuous education and the use of goal-directed therapy (GDT) to improve patient care. Presented by Desiree Chappell and Monty Mythen with their guest Amy Yerdon, DNP, CRNA, Assistant Professor of Nursing, Nursing Acute, Chronic & Continuing Care, University of Alabama, Birmingham. Our guest previously featured on TopMedTalk here: https://www.topmedtalk.com/podcasts/intraoperative-hypotension-killing-them-softly-topmedtalk-at-the-aana/
Unlock the secrets to improving anesthesia patient safety as we tackle the critical issue of intraoperative hypotension. Did you know that hypotension during surgery can lead to severe complications like acute kidney injury, myocardial injury, delirium, and stroke? Join us as we dissect recent studies, including one by Ariyarathna and colleagues linking high vasopressor use to kidney damage, and another by Chiu and colleagues on the dangers of limiting IV fluid administration. With expert insights from Amy Yerdon, Matt Scherrer, and Desiree Chappell, this episode is packed with essential information on minimizing hypotensive events and optimizing patient outcomes through advanced monitoring and goal-directed therapy.Stay ahead in your practice by understanding the differential diagnosis for intraoperative hypotension and the importance of continuous blood pressure monitoring. Learn strategies to balance fluid and vasopressor use effectively, ensuring patient safety. Whether you're an anesthesia professional or simply interested in medical advancements, this episode offers valuable knowledge and practical tips to enhance postoperative recovery. Don't miss out on these crucial insights that could transform your approach to anesthesia care.For show notes & transcript, visit our episode page at apsf.org: https://www.apsf.org/podcast/219-optimizing-outcomes-in-anesthesia-care-spotlight-on-intraoperative-hypotension/© 2024, The Anesthesia Patient Safety Foundation
Hypotension and shock are both recognized as complications post-cardiac surgery. Some patients may develop more severe shock refractory to fluids and catecholamines. This response is also known as today's podcast episode, topic: vasoplegia after cardiac surgery. For this discussion, Dr. Zanotti is joined by Dr. Iqbal Ratnani, an intensivist who practices at the DeBakey Heart & Vascular Center and the Center for Critical Care at Houston Methodist Hospital. Dr. Ratnani is an Associate Professor of Clinical Anesthesiology & Critical Care for the Department of Anesthesiology and Critical Care at Weill Cornell Medical College. In addition, Dr. Ratnani is the Director of Critical Care Education at the Center for Critical Care. Additional resources: Vasoplegia: A Review. Igbal Ratnani, et al. Methodist DeBakey Cardiovascular Journal 2023: https://pubmed.ncbi.nlm.nih.gov/37547893/ Vasoplegic Syndrome after Cardiopulmonary Bypass in Cardiovascular Surgery: Pathophysiology and Management in Critical Care. Zied Ltaief, et al. Journal of Clinical Medicine 2022: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658078/ Books mentioned in this episode: Marino's The ICU Book. By Paul Marino: https://bit.ly/3XmWPGA Every Deep-Drawn Breath. By Wes Ely: https://bit.ly/4cODkeq In Shock: My Journey from Death to Recovery to Redemption. By Rana Awdish: https://bit.ly/3Z4mC7z
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode948. In this episode, I'll discuss postintubation hypotension following rapid sequence intubation with full vs. reduced-dose induction agent. The post 948: Does reducing the induction agent dose lessen the chance of postintubation hypotension? appeared first on Pharmacy Joe.
Send us a Text Message.Vasopressin as adjunctive therapy in pulmonary hypertension associated with refractory systemic hypotension in term newborns.Santelices F, Masoli D, Kattan J, Toso A, Luco M.J Perinatol. 2024 Jul 4. doi: 10.1038/s41372-024-02015-0. Online ahead of print.PMID: 38965377 As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
Join us this week as we dive into the complexities of Postural Orthostatic Tachycardia Syndrome (P.O.T.S.) with Dr. Carissa Doherty, ND. Dr. Doherty ND sheds light on the different types of P.O.T.S. and how the COVID-19 pandemic has increased awareness of this often under-recognized condition. Discover how Long COVID has brought POTS-like symptoms, such as orthostatic intolerance, into the spotlight and what this means for patients and healthcare providers alike.The information presented on this podcast is for educational purposes only. It is not intended to diagnose or prescribe for any medical or psychological condition, nor prevent, treat, mitigate, or cure any conditions. Please make your own healthcare decisions based on your judgment and research in partnership with a qualified healthcare professional.Become a supporter of this podcast: https://www.spreaker.com/podcast/that-naturopathic-podcast--4229492/support.
Severe orthostatic headaches could indicate a serious condition called spontaneous intracranial hypotension (SIH). Neurologist Will Meador, M.D., and interventional neuroradiologist Jesse Jones, M.D., discuss how they interpret a combination of symptoms and imaging to make diagnoses and the common first-line treatments for cases that do not resolve with conservative lifestyle interventions. Learn details about a complex surgery to address severe cases.
For the full video, check out the Final Exam Coursehttps://anaesthesia.thinkific.com/courses/finalexamExam StemYou are seeing a 14yo female accompanied by her mother in preadmission clinic. She's booked for a planned multilevel thoracic spine fixation in two week's time for idiopathic scoliosis. Her regular medications are - Paracetamol - PRN diclofenac - Esomeprazole- Multivitamin - Vitamin D - Symbicort - Fluoxetine Past Medical History - Childhood asthma - Idiopathic scoliosis - Anxiety and depression Vitals - HR 80, - BP 110/70, - RR 16- Sats 97%- Height 156cm- 48kgShe attends the local high school.What are the components of informed consent? ---------Find us atInstagram: https://www.instagram.com/abcsofanaesthesia/Twitter: https://twitter.com/abcsofaWebsite: http://www.anaesthesiacollective.comPodcast: ABCs of AnaesthesiaPrimary Exam Podcast: Anaesthesia Coffee BreakFacebook Page: https://www.facebook.com/ABCsofAnaesthesiaFacebook Private Group: https://www.facebook.com/groups/2082807131964430---------Check out all of our online courses and zoom teaching sessions here!https://anaesthesia.thinkific.com/collectionshttps://www.anaesthesiacollective.com/courses/---------#Anesthesiology #Anesthesia #Anaesthetics #Anaesthetists #Residency #MedicalSchool #FOAMed #Nurse #Medical #Meded ---------Please support me at my patreonhttps://www.patreon.com/ABCsofA---------Any questions please email abcsofanaesthesia@gmail.com---------Disclaimer: The information contained in this video/audio/graphic is for medical practitioner education only. It is not and will not be relevant for the general public.Where applicable patients have given written informed consent to the use of their images in video/photography and aware that it will be published online and visible by medical practitioners and the general public.This contains general information about medical conditions and treatments. The information is not advice and should not be treated as such. The medical information is provided “as is” without any representations or warranties, express or implied. The presenter makes no representations or warranties in relation to the medical information on this video. You must not rely on the information as an alternative to assessing and managing your patient with your treating team and consultant. You should seek your own advice from your medical practitioner in relation to any of the topics discussed in this episode' Medical information can change rapidly, and the author/s make all reasonable attempts to provide accurate information at the time of filming. There is no guarantee that the information will be accurate at the time of viewingThe information provided is within the scope of a specialist anaesthetist (FANZCA) working in Australia.The information presented here does not represent the views of any hospital or ANZCA.These videos are solely for training and education of medical practitioners, and are not an advertisement. They were not sponsored and offer no discounts, gifts or other inducements. This disclaimer was created based on a Contractology template available at http://www.contractology.com.
This piece is part of our coverage of The International Anesthesia Research Society (IARS) annual meeting. This wide ranging conversation tackles hemodynamics, intraoperative hypotension and its implications. We also discuss finance for medical practitioners and patient-centered research. Presented by Desiree Chappell, Vice President of Clinical Quality at NorthStar Anesthesia and TopMedTalk co-editor in Chief and Monty Mythen, TopMedTalk's founder and Senior Vice President Medical Affairs, Edwards Lifesciences with their guest Wael Saasouh, Anesthesiologist and Director of Research for NorthStar Anesthesia.
Commentary by Dr. Valentin Fuster
The first multidisciplinary consensus guideline for the diagnosis and treatment of spontaneous intracranial hypotension (SIH) has recently been published by the UK SIH Specialist Interest Group. Group members Prof. Manjit Matharu (1), Dr. Indran Davagnanam (2), and Mr. Parag Sayal (3) join Dr. Amy Ross-Russell to explain their recommendations. They discuss the impact this condition has on patients, the possible presentations, and approaches for diagnosis and treatment. Read the article: Spontaneous intracranial hypotension (1) Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, London, UK (2) Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, UK (3) Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK
Radiology read to you! Frank reads our spontaneous intracranial hypotension article to neuroradiologist and CSF leak expert Lalani Carlton Jones. Workup and management of CSF leaks has evolved rapidly over recent years so this will be a much needed update for many listeners. Radiopaedia's spontaneous intracranial hypotension article ► https://radiopaedia.org/articles/spontaneous-intracranial-hypotension-2 Radiopaedia's CSF venous fistula article ► https://radiopaedia.org/articles/csf-venous-fistula Radiopaedia 2024 Virtual Conference ► https://radiopaedia.org/courses/radiopaedia-2024-virtual-conference Become a supporter ► https://radiopaedia.org/supporters Get an All-Access Pass ► https://radiopaedia.org/courses/all-access-course-pass Andrew's X ► https://twitter.com/drandrewdixon Frank's X ► https://twitter.com/frankgaillard Ideas and Feedback ► podcast@radiopaedia.org The Reading Room is a radiology podcast intended primarily for radiologists, radiology registrars and residents.
CHEST April 2024, Volume 165, Issue 4 Elizabeth S. Munroe, MD, joins CHEST Podcast Moderator Dominique Pepper, MD, to discuss the use of vasopressors in routine practice and potential associations between vasopressor initiation route and in-hospital mortality. DOI: https://doi.org/10.1016/j.chest.2023.10.027 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.
Low blood pressure during surgery is common in patients having non-cardiac surgery under general anesthesia. This can be secondary to many factors but has been linked to major postoperative complications such as renal failure to myocardial injury and even death. On today's episode of Clinical Pearls, we have an expert in this field. Amy Yerdon, DNP, MNA, CRNA, CNE, is an Assistant Professor in the UAB School of Nursing and the BSN-DNP Nurse Anesthesia Assistant Program Director.
Our coverage of the 18th World Congress of Anaesthesiologists (WCA 2024) continues. In this piece we cover assisted fluid management in anesthesia. Using AI in anesthesia and its potential impact on anesthesiologists. The validity of the hypotension prediction index in academic debate. Reducing hypertension in surgical patients using HPI. Desiree Chappell and Monty Mythen speak with Thomas Scheeren, Senior Director Medical Affairs, Edwards Lifesciences and Paul Van Beest, Anaesthesiologist, Medical Center Leeuwarden, University Medical Center Groningen.
Host: Jasmine T. Kency, M.D., Assistant Professor of Internal Medicine and Pediatrics at the University of Mississippi Medical Center.Topic: Questions from the Clinic: Hypertension, Hypotension, Flu, Over the Counter Medication, and MoreEmail the show: remedy@mpbonline.org. Hosted on Acast. See acast.com/privacy for more information.
Commentary by Dr. Valentin Fuster
In this episode, we're tackling the topic of hypotension and exploring intervention and management strategies. Additionally, we're diving deep into the various types of shock, discussing how treatment approaches differ based on the underlying cause. There's no universal solution; each case requires careful assessment to identify the type of shock and tailor the treatment plan accordingly. Join us as we navigate through the complexities of these conditions and share insights on effective management strategies.Support the showTo access all of our content, download the CORE Anesthesia App available here on the App Store and here on Google Play. Want to connect? Check out our instagram or email us at info@coreanesthesia.com
Host: Jasmine T. Kency, M.D., Assistant Professor of Internal Medicine and Pediatrics at the University of Mississippi Medical Center.Topic: Questions from the Clinic: Hypertension, Hypotension, Flu, Over the Counter Medication, and MoreEmail the show: remedy@mpbonline.org. Hosted on Acast. See acast.com/privacy for more information.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode878. In this episode, I'll discuss the prediction of hypotension from propofol when used as an ICU sedative. The post 878: Here Is How You Can Predict Hypotension From Propofol appeared first on Pharmacy Joe.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode878. In this episode, I ll discuss the prediction of hypotension from propofol when used as an ICU sedative. The post 878: Here Is How You Can Predict Hypotension From Propofol appeared first on Pharmacy Joe.
Wendy presents with a recent diagnosis of Addison's disease and has. been referred to physical therapy. During exercise, the therapist should expectant of which of the following symptoms? A. Hypertension and tachycardia B. Hyperglycemia and diaphoresis C. Hypotension and fatigue D. Hypoglycemia and hyperreflexia LINKS MENTIONED: Did you get this question wrong?! If you were stuck between two answers and selected the wrong one, then you need to visit www.NPTEPASS.com, to learn about the #1 solution to STOP getting stuck. Are you looking for a bundle of Coach K's Top MSK Cheatsheets? Look no further: www.nptecheatsheets.com --- Support this podcast: https://podcasters.spotify.com/pod/show/thepthustle/support
Intraoperative hypotension is now firmly associated with harm and poor outcomes, this conversation should get you thinking about what this means to you as a practitioner. Here Desiree Chappell speaks with Amy Yerdon, Assistant Professor of Nursing, Nursing Acute, Chronic & Continuing Care, University of Alabama, Birmingham and Bradley Steg, CRNA is a Nurse Anesthetist in Jackson, Tennessee.
The Pharm So Hard Podcast: An Emergency Medicine and Hospital Pharmacy Podcast
Guest For the podcast Rosa Malloy-Post Hometown: Brooklyn, NY College: Fort Lewis College Durango, CO Medical school: University of Colorado What you love about living in/moving to Charlotte: The food and the trees. Coming from Denver it's nice to have some greenery. The variety and concentration of good food is impressive, I haven't had a bad meal yet. What you […] The post Episode 110. The use of Methylene Blue for Refractory Hypotension with Rosa Malloy-Post, MD appeared first on The Pharm So Hard Podcast.
This important piece covers the recent Anestheia Patient Safety Foundation (APSF) conference on perioperative hemodynamic instability, and the recent recommendations that they have just launched. The Anestheia Patient Safety Foundation is here: https://www.apsf.org/ Presented by Desiree Chappell and Mike Grocott with their guests, Daniel Cole MD, APSF President, Louise Y. Sun MD, SM, FRCPC , FAHA Professor of Anesthesiology at Stanford University, Michael Scott MB, ChB, FRCP, FRCA, FFICM Professor of Anesthesiology at the University of Pennsylvania. -- Originally streamed live as part of our coverage of Anesthesiology 2023; the annual meeting of the American Society of Anesthesiologists (ASA), the largest and most important gathering of anesthesiologists in the world. We're your free front row seat. For more on the ASA go here: https://www.asahq.org/ Check out our YouTube page for a record of the live stream video of this podcast: https://www.youtube.com/@topmedtalk7687/streams
Imagine you are anesthetizing your last patient of the day, and the alarm for the anesthesia machine is blaring, warning that your patient's blood pressure is far too low. The machine reads 80/40 (55). It probably doesn't seem too hard to imagine, because anesthesia-induced hypotension is one of the most common cardiovascular complications of general anesthesia. In this episode, host Dr. Bonnie Gatson welcomes Dr. Vaidehi Paranjape. Not only is Dr. Paranjape a board-certified veterinary anesthesiologist and assistant professor at Virgina-Maryland College of Veterinary Medicine, but she has also focused her research career on understanding how to appropriately identify, measure, and manage cardiovascular problems under general anesthesia. We will answer your burning questions about blood pressure monitoring, including: what are we measuring when we take an animal's blood pressure, how do we know if we are measuring blood pressure correctly, which is the most accurate indirect method of measuring blood pressure: oscillometric or Doppler, and what are the most appropriate steps to take when dealing with a hypotensive patient under anesthesia?We invite our listeners to check out articles mentioned in today's episode: 2020 AAHA Anesthesia and Monitoring Guidelines for Dogs and Cats ACVAA Recommendations for Anesthesia Monitoring in horses and small animals ACVIM consensus statement on the identification, evaluation, and management of systemic hypertension in dogs and cats Veterinary Blood Pressure SocietyIf you like what you hear, we have a couple of favors to ask of you:Become a member at North American Veterinary Anesthesia Society (NAVAS) for access to more anesthesia and analgesia educational and RACE-approved CE content.Spread the word. Share our podcast and FB/IG posts, re-tweet, post something on a network or a discussion forum, or tell a friend over lunch. That would really help us achieve our mission: Reduce mortality and morbidity in veterinary patients undergoing sedation, anesthesia, and analgesia through high-quality, peer-reviewed education.We also ask our listeners to save the date for the NAVAS Virtual Spring Symposium on April 27th and 28th, 2024. For more information about the program, visit the NAVAS Spring Symposium website. Dr. Paranjape will be one of our featured speakers during the symposium, and several speakers will discuss blood pressure management under anesthesia.Thank you to our sponsor, Dechra - learn more about the pharmaceutical products Dechra has to offer veterinary professionals, such as Zenalpha.If you have questions about this episode or want to suggest topics for future episodes, reach out to the producers at education@mynavas.org.All opinions stated by the host and their guests are theirs alone and do not represent the thoughts or opinions of any corporation, university, or other business or governmental entity.The NAVAS Podcast is published monthly on or near the 15th of the month.Special thanks to Chris Webster for editing, producer Maria Bridges, and Saul Jimenez for IT support in making this podcast a reality.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode853. In this episode, I’ll discuss how to predict hypotension from dexmedetomidine. The post 853: Can hypotension from dexmedetomidine be predicted? appeared first on Pharmacy Joe.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode853. In this episode, I’ll discuss how to predict hypotension from dexmedetomidine. The post 853: Can hypotension from dexmedetomidine be predicted? appeared first on Pharmacy Joe.
Dr. Tesha Monteith talks with Dr. Wouter Schievink about what spontaneous intracranial hypotension is and why it's commonly misdiagnosed. Full podcast: https://directory.libsyn.com/episode/index/id/27833880
Dr. Tesha Monteith talks with Dr. Wouter Schievink about what spontaneous intracranial hypotension is and why it's commonly misdiagnosed. Visit NPUb.org/Podcast for additional podcasts and associated article links.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode838. In this episode, I'll discuss whether there is an association between the sedative dose and postintubation hypotension and rapid sequence intubation. The post 838: Hypotension After Intubation – Is It the Sedative Dose That Matters? appeared first on Pharmacy Joe.
The Elective Rotation: A Critical Care Hospital Pharmacy Podcast
Show notes at pharmacyjoe.com/episode838. In this episode, I ll discuss whether there is an association between the sedative dose and postintubation hypotension and rapid sequence intubation. The post 838: Hypotension After Intubation – Is It the Sedative Dose That Matters? appeared first on Pharmacy Joe.
Dr. Derek Stitt talks with Dr. Andrew Callen about the relationship between bern score, spinal elastance, and opening pressure in patients with spontaneous intracranial hypotension. Read the related article in Neurology. For links to articles and previous podcast episodes, please visit NPUb.org/Podcast. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.