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Decision fatigue and role confusion often show up in the body first. If growth feels unsafe or expansion feels overwhelming, this episode explains how recalibration retrains your nervous system to embrace alignment instead of fear.Why does growth feel unsafe even when you know it's right? For many high-capacity humans, the barrier to expansion isn't strategy or skill — it's the nervous system itself.In this episode of The Recalibration, Julie Holly unpacks why the body often resists aligned growth. Neuroscience explains it through predictive processing and the reticular activating system (RAS) — the brain prefers what it can predict, even if it's unfulfilling. That's why new opportunities trigger anxiety, decision fatigue, and self-protection.Through personal stories of endurance cycling and the challenges of marriage, Julie shows how resistance reveals deeper scripts like Prover or Performer. And through the story of Brian Chesky, cofounder of Airbnb, you'll see how expansion that once felt unsafe can become the pathway to global transformation.Here's where Identity-Level Recalibration (ILR) shifts everything. Your nervous system is wired for survival, not alignment. ILR re-patterns this response, teaching your body that newness doesn't equal danger — it equals alignment. Unlike mindset tactics or productivity hacks, ILR is the root-level recalibration that makes every other tool effective.If success feels empty, if you're exhausted by performance pressure, or if you've been resisting growth because it “feels risky,” this episode will help you see what's really happening — and how to lead yourself and others into expansion that lasts.Today's Micro Recalibration:Where is my body confusing risk with danger?How can I reassure it that growth is safe?As a leader, how might I help my team reframe risk as alignment?If this episode gave you language you've been missing, please rate and review the show so more high-capacity humans can find it. Explore Identity-Level Recalibration→ Follow Julie Holly on LinkedIn for more recalibration insights → Schedule a conversation with Julie to see if The Recalibration is a fit for you → Download the Misalignment Audit → Subscribe to the weekly newsletter → Join the waitlist for the next Recalibration cohort This isn't therapy. This isn't coaching. This is identity recalibration — and it changes everything.
So much of your food and body battle comes down to one thing: belief. The women who finally break free from diet culture aren't the ones with more willpower — they're the ones who learn to change the beliefs holding them back. In episode 260 of Fitness & Sushi, I'm going to show you why the beliefs you hold about yourself are the true drivers of your choices, and how to finally break free from the stories diet culture has planted in your mind. In this episode – “How to Break Free From Limiting Beliefs About Food, Your Body, and Exercise” – you'll learn…
Discover the “50 Ways” exercise that sparks creativity, expands opportunities, and helps you manifest more in business and life.Feeling stuck, uninspired, or limited in your options? In this episode of Biz Besties, Nicole and Kaila share their favorite tool to break through creative blocks: the “50 Ways” method.This simple but powerful exercise helps you brainstorm beyond limits, tap into your reticular activating system (RAS), and notice opportunities you may have been missing. From making more money to growing your audience or even finding your next big idea, this practice will expand your sense of possibility.You'll also hear how this exercise helped Nicole and Kaila expand into the US market—leading to aligned connections, new clients, and unexpected manifestations.Tune in and try it for yourself—you'll be surprised at what unfolds after idea number 25!Key TakeawaysThe 50 Ways Hack – Why forcing yourself to write down 50 ideas (even the silly ones) opens the door to creativity, new opportunities, and unexpected breakthroughs.Mindset + Environment Matter – How setting aside quiet space, using tools like binaural beats, and removing distractions helps you get into your creative “zone.”Manifestation in Action – Real-life examples of how this practice led to expanded opportunities, new clients, and even chance encounters that aligned with bigger goals.Want to magnetize more wealth and abundance? Grab our Frequency of Wealth Bundle here: https://www.myalignedpurpose.com/fow
Review các phim ra rạp từ ngày 26/09/25ĐỒI HÀNH XÁC – T18Đạo diễn: Lương Đình DũngDiễn viên: Hứa Vĩ Văn, Nguyễn Xuân Thắng,Thể loại: Hồi hộp, Kinh DịBảo là một chàng trai trẻ làm nghề sửa xe và đồng thời sở hữu một ga-ra xe hơi cũ. Khi tháo dỡ một chiếc xe từ thập niên 90, Bảo vô tình đánh thức một thế lực tà ác, kéo theo hàng loạt sự kiện kỳ dị xảy đến với anh và những người xung quanh. Cùng với sự có mặt của một điều tra viên bí ẩn (Hứa Vĩ Văn), bí mật từ quá khứ đội mồ sống dậy, bóc trần những góc khuất của lòng tham và sự tàn bạo nơi con người.EXIT 8: GA TÀU VÔ TẬN – T16Đạo diễn: Genki KawamuraDiễn viên: Kazunari Ninomiya, Yamato Kochi, Thể loại: Kinh DịBộ phim xoay quanh một chàng trai trẻ bị mắc kẹt trong một hành lang tàu điện ngầm vô tận và lạnh lẽo. Tại đây, anh chàng bất đắc dĩ phải tham gia vào một trò chơi tìm kiếm “lối ra số 8”. Vòng đầu tiên sẽ bắt đầu từ “lối ra số 0”, luật chơi tưởng chừng rất đơn giản: Đừng bỏ qua bất kỳ điều gì bất thường ở hành lang của mỗi lối ra. Nếu phát hiện điều gì sai, hãy lập tức quay đầu. Nếu không thấy gì thay đổi, cứ đi tiếp. Nhưng chỉ một lần lơ là, người chơi lập tức trở về điểm xuất phát. Giữa mê cung vô tận với những cơn ảo giác ập đến, liệu anh chàng có thể giành chiến thắng và trở về với thực tại?TRẬN CHIẾN SAU TRẬN CHIẾN – T18Đạo diễn: Paul Thomas AndersonDiễn viên: Leonardo DiCaprio, Sean Penn, Benicio Del Toro, ..Thể loại: Hành Động, Hồi hộp, Tâm LýBob Ferguson (Leonardo DiCaprio) và vợ từng là thành viên của một tổ chức cách mạng mang tên French 75. Nhiều năm sau, một sự kiện bất ngờ xảy ra khi cô con gái tuổi teen của cả 2, Willa (Chase Infiniti) bất ngờ bị bắt cóc. Để giúp Bob tìm lại con gái, những nhà cách mạng trong tổ chức đã cùng hợp tác với nhau một lần nữa. Trên hành trình tìm kiếm Willa, Bob cùng những đồng đội của mình không chỉ giáp mặt những kẻ thù cũ mà còn chứng kiến những bí mật từ quá khứ lần lượt bước ra ánh sáng.Xác Chết Về Quê – T16Đạo diễn:Adriano RudimanDiễn viên:Aghniny Haque, Thể loại:Kinh dịRas và Yudhis chỉ muốn chôn vùi nỗi đau buồn của họ - Nhưng thi thể của cha họ đã trỗi dậy và bước đi. Điều gì thực sự còn dang dở?CHAINSAW MAN - THE MOVIE: CHƯƠNG REZE – T18Đạo diễn: Tatsuya YoshiharaDiễn viên: Kikunosuke Toya, Thể loại: Hành Động, Hoạt Hình, Thần thoạiỞ phần trước, ta đã biết Denji từng làm Thợ Săn Quỷ cho yakuza để trả món nợ của cha mẹ nhưng bị họ phản bội và trừ khử. Trong khoảnh khắc hấp hối, chú chó quỷ cưa máy Pochita (người bạn đồng hành trung thành của Denji) đã đưa ra một khế ước, cứu sống cậu và hợp thể cùng cậu. Từ đó, một Quỷ Cưa bất khả chiến bại ra đời. Giờ đây ở Chainsaw Man – The Movie: Chương Reze, trong cuộc chiến tàn khốc giữa quỷ dữ, thợ săn quỷ và những kẻ thù trong bóng tối, một cô gái bí ẩn tên Reze xuất hiện trong thế giới của Denji. Denji buộc phải đối mặt với trận chiến sinh tử khốc liệt nhất của mình, một trận chiến được tiếp sức bởi tình yêu trong một thế giới nơi mọi người phải sinh tồn mà không biết bất kỳ luật lệ nào.NHÀ BÚP BÊ CỦA GABBY: PHIM ĐIỆN ẢNHĐạo diễn: Ryan CregoDiễn viên: Laila Lockhart Kraner, Kristen Wiig,...Thể loại: Hoạt Hình, Phiêu LưuBộ phim xoay quanh câu chuyện Gabby cùng bà ngoại Gigi lên đường đến xứ sở thần tiên đô thị Cat Francisco. Nhưng khi ngôi nhà búp bê của Gabby, vật sở hữu quý giá nhất của cô, rơi vào tay một bà mèo lập dị tên Vera, Gabby bắt đầu cuộc phiêu lưu vào thế giới thực để đoàn tụ với những chú mèo Gabby và cứu ngôi nhà búp bê trước khi quá muộn.BTS 2016 LIVE THE MOST BEAUTIFUL MOMENT IN LIFE ON STAGE: EPILOGUE REMASTEREDĐạo diễn: Jo HyeongseokThể loại: Hòa nhạc, Phim tài liệuTrở lại với hồi kết huy hoàng của series “The Most Beautiful Moment in Life” – nơi tuổi trẻ rực rỡ nhất được khắc họa qua âm nhạc và sân khấu của BTS.-------------------------------------------#8saigon #reviewphimrap #doihanhxac #exit8gatauvotan #tranchiensauttranchien
How to achieve your Dreams and Goals Want real results — not hype? In this episode of Personal Development Unplugged Paul Clough shows you how to move from wishful thinking to action that works. We dig into practical goal-setting, the feeling of the wish fulfilled, how to use your mind (RAS + visualization), and small, actionable steps that create momentum. Expect NLP-informed tips, a short guided hypnosis process to embed success in your unconscious, and direct coaching you can use today. Key takeaways Define success specifically: the clearer the goal, the faster the result. Use feeling of the wish fulfilled + physiology + inner dialogue to “act as if.” Employ the Reticular Activating System—focus your mind and notice opportunities. Build micro-steps (tiny wins) and schedule regular reviews to stay on track. Align goals with your values — ensure they're ecological (good for you, others, planet). Quick practical guided hypnosis included — make this a daily habit. Share with one person who needs permission to step up today. Have more fun than you can stand. https://personaldevelopmentunplugged.com/463-how-to-achieve-your-dreams-and-goals Shine Brightly
On hour two of Flames Talk, it's the Eric Francis Hour with Sportsnet's Eric Francis! Pat Steinberg and Eric Francis kick off the hour by diving to the latest on Rasmus Andersson and our new fundraiser, Ras for Cash! Eric dives into his latest article on the door potentially remaining open to Rasmus Andersson re-signing with the Flames, how that fact could benefit both sides, and Pat shares why he thinks Andersson will eventually be traded.(18:36) The guys break down the latest on the Flames' backup goaltender competition as Devin Cooley is set to make his best push for the spot Saturday against the Winnipeg Jets! The guys debate who they think will have the leg up to get the backup job to start the season, and some of the other battles around the roster!The views and opinions expressed in this podcast are those of the hosts and guests and do not necessarily reflect the position of Rogers Media Inc. or any affiliate. https://www.sportsnet.ca/960/flames-talk/
Argumenterar för ett färgblint samhälle i ny bok. Lyssna på alla avsnitt i Sveriges Radio Play. I USA har president Trump tagit upp kampen mot vad han anser är splittrande idéer som slagit klorna i kulturlivet. Och även om man kan ha synpunkter på hans metoder så har han i grunden rätt - det menar författaren och debattören Coleman Hughes, aktuell med boken "Färgblind - en strävan bortom raspolitik". P1 Kulturs Mårten Arndtzén har träffat honom på besök i Stockholm.
Understanding Focus: The RAS Have you ever noticed that once you buy a new car, suddenly that model seems to be everywhere? Or you hear a new word and then it pops up all the time? That's not magic – it's your Reticular Activating System (RAS) at work. In this Five Minute Quickie, I'm breaking down the RAS in plain English. It's the part of your brain that decides what to notice – and it's powered by emotion. The good news? You can train it to look for opportunities, positivity, and success. The bad news? If you're stuck in negative emotions, it will keep showing you reasons to stay stuck. So let's flip the switch. Learn how to focus on what serves you rather than what drags you down. Because when you understand your RAS, you can use it to fuel your goals, dreams, and everyday happiness. And keep listening – in the next longer episode I'll guide you through a process (with a bit of hypnosis) to help your unconscious mind focus deeply on what you truly want. You could start by focusing on sharing. Here is a link to this episode https://personaldevelopmentunplugged.com/fmq-514-understanding-focus-the-ras Shine Brightly
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-451 Overview: The obesity epidemic has fueled a demand for weight loss medications. Trials have directly compared medications—specifically glucagon-like peptide-1 receptor agonists (GLP-1 RAs)—with a recent study doing just that. Tune in as we explore the evidence comparing semaglutide and tirzepatide for weight loss outcomes up to 1 year. Episode resource links: Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, et al. Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity. JAMA Intern Med. 2024;184(9):1056-1064. Moiz A, Filion KB, Toutounchi H, et al. Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials. Ann Intern Med. 2025;178(2):199-217. Wen J, Syed B, Nadora D, et al. Tirzepatide Versus Semaglutide on Weight Loss in Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis of Direct Comparative Studies. Endocrinol Diabetes Metab. 2025;8(3):e70045. Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-451 Overview: The obesity epidemic has fueled a demand for weight loss medications. Trials have directly compared medications—specifically glucagon-like peptide-1 receptor agonists (GLP-1 RAs)—with a recent study doing just that. Tune in as we explore the evidence comparing semaglutide and tirzepatide for weight loss outcomes up to 1 year. Episode resource links: Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, et al. Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity. JAMA Intern Med. 2024;184(9):1056-1064. Moiz A, Filion KB, Toutounchi H, et al. Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials. Ann Intern Med. 2025;178(2):199-217. Wen J, Syed B, Nadora D, et al. Tirzepatide Versus Semaglutide on Weight Loss in Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis of Direct Comparative Studies. Endocrinol Diabetes Metab. 2025;8(3):e70045. Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Viete, čo máme úplne všetci spoločné pri narodení a hneď od začiatku nám to je prirodzené tak ako dýchanie? Kreativita. Dospelí vidia zlomený suchý konár, deti vidia čarovný prútik. My vidíme obyčajný kameň, no tí najmenší vidia vzácny drahokam. Kedy a prečo sa z nás kreativita vytráca? Vplyv na to majú aj dospeláci, s ktorými sme boli v kontakte počas nášho detstva. Existujú však ľudia, ktorí v nás dokážu opäť zapáliť oheň kreativity. Jeden z nich je aj kreatívec a sprievodca vedomou kreativitou Rasťo Michalík.
Retirement is often envisioned as the reward at the end of a long career, but too many people find themselves adrift once finances are settled, lacking a sense of purpose and fulfillment. Cyn Meyer, author of "The Rewire Retirement Method: Ailing from Aimless to Amazing," and founder of Second Wind Movement, offers a transformative approach to redefining retirement—one built not on financial spreadsheets, but on neuroscience, clarity, and sustained personal growth.From Aimless to Amazing: Redefining RetirementTraditional retirement planning focuses almost exclusively on money—401ks, nest eggs, and the dream of untethered leisure—but the real challenge is psychological and emotional. Meyer's experience as a life coach for retirees, combined with personal family events and a background in neuroscience, led her to create a system that unlocks genuine fulfillment after career ends. She saw firsthand retirees with substantial assets fall into a "retirement rut": losing momentum, purpose, and zest for living, which often gives way to anxiety, depression, and a sedentary lifestyle.The Rewire Retirement SystemMeyer's method, built into a three-month program and distilled in her book, centers around clarity before action. Instead of rushing to fill time with stereotypical pursuits like pickleball or beach days, her system guides individuals to uncover their authentic identity for this new phase. The process leverages neuroscience, notably the reticular activating system (RAS), prodding the brain daily toward new, meaningful pathways that fuel purpose.The method breaks retirement into "Five Rings," each representing a part of this holistic journey:Giving Back: Community involvement, volunteering, sharing wisdom.Recreation: Physical, creative, and leisure pursuits.Connection: Building deeper relationships and family ties.Personal Growth: Learning new skills, overcoming challenges.Legacy: Creating impact and meaning, be it through family, professional boards, or artistic expression.Rather than an all-at-once overhaul, the program recommends microsteps—small, daily actions (about 20 minutes a day)—to incrementally build a life that is both unique and deeply satisfying. The approach emphasizes that retirement is a launchpad for upward growth, not a period of descent or withdrawal.Real Success and ResilienceThe outcomes of Meyer's approach are as unique as the individuals who use it. Some find renewed drive—like the client who, after severe health setbacks and mini-strokes, used the microstepping system to reconnect with family, grow stronger physically, and hike mountains by age 70. Others discover latent passions, such as joining professional boards, writing books, or grandparenting with deeper relationships.Importantly, Meyer notes that the age at which someone begins this journey is irrelevant—what matters is the internal search for what's missing. Everyone is vulnerable to feeling "rudderless" if purpose is lacking, regardless of physical health or previous achievements. Her message is clear: when that subtle void appears, it's time to act.Individuality Over ComparisonOne vital lesson Meyer shares is to resist comparing retirement journeys. Each person is an individual, with unique dreams, goals, and intrinsic motivators. The path in this new chapter should be drawn inwardly, not by keeping up with the societal or financial benchmarks of others.Getting Started: Tools and AccessFor those interested, Meyer offers entry points through her website, SecondWindMovement.com, which includes a free masterclass and courses such as the 14-day Purpose Jumpstart. Her book is available for deeper self-guided exploration. The goal is accessibility for anyone, not just those who can afford private coaching.
The Bon Appétit test kitchen was a beloved comfort channel of the late 2010's serving up wholesome, bingeable and feel-good content for foodies across the globe. But behind the scenes systemic racism, pay inequities and mistreatment of POC staff revealed an ugly truth beyond the "BA Family" facade. This week we tackle arguably the biggest and most shocking cancellation of 2020 and discuss the unexpected downfall of Bon Appétit!Say au revoir to Bon Appétit and most importantly - let me know what you think!Instagram - @moodforfeud TikTok - @moodforfeud Support the show on Ko-fi all funds go towards upgrading my podcast gear!01:26 Why I loved Bon Appétit04:54 The magazine to YouTube pipeline09:51 YouTube rebrand and success18:20 The downfall39:39 Business Insider expose on Bon Appétit46:32 The aftermathLinksThe Bon Appétit test kitchen's race problemYarWritten by Ryan SkeltonProduced by Ras & Sakunera#BonAppetit #TestKitchen #BradLeone #ClaireSaffitz #FoodMedia #CondeNast #GourmetMakes #FoodScandal #CancelCulture #FoodieDrama #MoodForFeud
Med ett förändrat klimat väntas fler ras och skred som de som nu skett i Ångermanland. Men det går att förebygga dem. Lyssna på alla avsnitt i Sveriges Radio Play. Efter de senaste skyfallen i Västernorrland står många kvar i chock – vägar har spolats bort, samhällen har isolerats, och en människa har tragiskt nog mist livet. Nu pekar experterna på att det här förmodligen inte är ett engångsfenomen. Med klimatförändringarna väntas ras, skred och översvämningar bli både fler och dyrare att röja upp efter. Men det finns hopp – rätt insatser i tid kan skydda både människor, bostäder och landskap. I det här programmet möter du experterna som har räknat på riskerna och som vet vad som behöver göras. Medverkande: HannaSofie Pedersen, chef för strategisk klimatanpassning på Statens Geotekniska Institut, som identifierat riskområden för ras och skred och analyserat hur mycket vanligare de kan bli fram över. Sandra Fyrstedt, gruppchef inom prognos- och varningstjänsten på SMHI, och Fredrik Birging på P4 Västernorrland, som varit på de drabbade platserna i veckan.Producent: Sara Sällströmsara.sallstrom@sverigesradio.seProgramledare: Camilla Widebeckcamilla.widebeck@sverigesradio.se
Günümüzde merak edilen konulardan birisi de Allâh (c.c.) cemalinin ahirette görülmesi (Ruyetullâh) meselesidir. Allâh Rasûlü (s.a.v.) Efendimiz ahirette Allâh'ın cemalinin cennetliklere bir ikram olarak görüleceğini sahih Hadis-i Şerif'lerinde bizlere bildirmiştir. Cerîr İbni Abdullah (r.a.): “Bir gece Resûlullah'ın yanında bulunuyorduk. On dördüncü gecesindeki Ay'a baktıktan sonra şöyle buyurdu: “Şu Ay'ı hiçbir sıkıntı çekmeden gördüğünüz gibi Rabbinizi de ayan beyan göreceksiniz.”(Buhârî) Suheyb (r.a.)'dan rivayet edildiğine göre Resûlullâh (s.a.v.) şöyle buyurdu: “Cennetlikler cennete girince Allah Teâlâ onlara:“Size vermemi istediğiniz bir şey var mı?” diye soracak. Onlar: “Yâ Rabbî! Yüzlerimizi ak etmedin mi? Bizi cennete koyup cehennemden kurtarmadın mı, daha ne isteyelim”, diyecekler. İşte o zaman Allah Teâlâ perdeyi kaldıracak. Onlara verilen en güzel ve en değerli şey Rablerine bakmak olacaktır.”(Müslim)Ehlullâh'tan büyük İslam Alimi İmam Rabbani Mektubat-ı Rabbani adlı eserinde bu konuyu şöyle izah eder: “Allahü Teâlâ'yı müminler cennette, cihetsiz olarak ve karşısında bulunmayarak, nasıl olduğu anlaşılmayarak,ihatasız, yani bir şekilde olmayarak görecektir.Allahü Teâlâ'yı ahirette görmeye inanırız. Nasıl görüleceğini düşünmeyiz. Çünkü, Onu görmeyi akıl anlayamaz. İnanmaktan başka çare yoktur. Felsefecilere ve Mutezile'ye ve Ehl-i Sünnet'ten başka bütün fırkalara yazıklar olsun ki,kör olduklarından, buna inanmaktan mahrum kaldılar. Görmedikleri, bilmedikleri şeyi gördükleri şeylere benzetmeye kalkarak iman şerefine kavuşamadılar.” (Mektubat-ı Rabbani, c.2, s.267)(Basından Derleme)
What if the abundance you're chasing is already trying to reach you—but you just can't receive it?In this episode I'm flipping the script on manifesting and getting honest about a pattern most of us don't even see: turning every gift into a transaction. From compliments and kindness to love and money—if you're struggling to hold what you say you want, receivership might be your missing piece.We dive into:The difference between attracting and chasingWhy your reticular activating system (RAS) is filtering out what you say you wantHow guilt, judgment, and the pleaser pattern block your ability to receiveA juicy story from Taiwan that brought all my own receivership edges to the surfaceIf you find yourself spiraling when someone gives you too much—or you can't accept generosity without paying it back—this episode is for you. No hacks. No fluff. Just the truth about receivership, and how to actually embody it.
In this week's bonus we run through the latest trending topics in popculture starting with my heated opinions about Emerald Fennel's Wuthering Heights trailer, then we discuss Cardi B's time in court, review Sabrina Carpenter's latest album Man's Best Friend and lastly give a quick update on some new Hollywood couples!Educate lawyers about wigs and most importantly - let me know what you think!Instagram - @moodforfeud TikTok - @moodforfeud Support the show on Ko-fi all funds go towards upgrading my podcast gear!Timestamps:00:51 Wuthering Heights trailer11:35 Cardi B in Court18:03 Man's Best Friend album27:03 Zoe Kravitz and Harry Styles30:34 Sydney Sweeney and Scooter Braun33:34 Pamela Anderson and Liam Neeson Update!Intro/Outro MusicYarWritten by Ryan SkeltonProduced by Ras & Sakunera#wutheringheights #margotrobbie #jacobelordi #sabrinacarpenter #mansbestfriend #cardib #celebritylawsuit #zoekravitz #harrystyles #sydneysweeney #scooterbraun #hollywoodcouples #popculturenews
Do najnovšej epizódy hokejového podcastu suSPEAK na ŠPORT.sk si moderátori Marek Marušiak a Rasťo Konečný pozvali muža, ktorý stojí za letnou prípravou našich elitných hokejistov na ľade. Matej Múčka, korčuliarsky špecialista a tréner, ktorý spolupracuje s hráčmi ako Tomáš Tatar či Pavol Regenda, otvorene porozprával o svojej ceste od aktívneho hokejistu k uznávanému trénerovi.Bývalý hráč Slovana a mládežnícky reprezentant Matej Múčka odhalil, ako ho zranenia prinútili prehodnotiť kariéru a ako sa napokon našiel v trénerskej profesii. „Začínal som v Česku na trénerských kempoch, kde ma prekvapilo, že deti mali dva tréningy denne a na oboch ani nevideli puk,” spomínal na svoje trénerské začiatky v Karlových Varoch, kde spoznal úplne iný prístup k hokejovej príprave.V rozhovore spoznáte aj pikantné detaily z tréningov hviezdnych profíkov, ktorí sa pod jeho vedením pripravujú v lete. „Martin Fehérváry príde a ihneď prvé, čo povie: ‚Dobre, o 5 eur!' Pavol Regenda zas miluje súťaže a doťahovačky,” usmieva sa pri spomienke na súťaživosť profesionálov, ktorí si neodpustia ani tie najmenšie stávky.Nezabudnuteľné sú spomienky Mateja Múčku na MS v hokeji do 18 rokov v Rusku, kde bol súčasťou generácie s Marekom Viedenským či Martinom Štajnochom. „Išli sme do oslabenia, vyhodili sme puk, Rišo Pánik uletel a gól na 1:0. To bola eufória!” zaspomínal si na zápas proti Rusku.Ešte väčší priestor venoval historke o trénerovi Milanovi Stašovi, ktorý na letisku nabíjal svoj telefón cez zásuvku pri obrovskom vianočnom stromčeku a spôsobil výpadok elektriny.Matej Múčka otvorene rozprával aj o svojej trénerskej filozofii. „Chcem byť pre deti autorita, ale aj kamarát a vzor. Snažím sa im ukázať každý cvik, aby videli, že sa to dá,” vysvetľuje s tým, že ho teší, keď u svojich zverencov vidí progres. Jeho ambíciou je posunúť sa do profi hokeja a pracovať aj s reprezentáciou.V zábavnej a inšpiratívnej najnovšej epizóde podcastu suSPEAK na ŠPORT.sk sa dozviete veľa nielen o hokejových zručnostiach, ale aj o tom, ako skúsenosť z I. ligy v Topoľčanoch, kde praváci hrali III. tretinu s ľavačkami, formovala cestu Mateja Múčku k vrcholovému trénerskému remeslu.
Do najnovšej epizódy hokejového podcastu suSPEAK na ŠPORT.sk si moderátori Marek Marušiak a Rasťo Konečný pozvali muža, ktorý stojí za letnou prípravou našich elitných hokejistov na ľade. Matej Múčka, korčuliarsky špecialista a tréner, ktorý spolupracuje s hráčmi ako Tomáš Tatar či Pavol Regenda, otvorene porozprával o svojej ceste od aktívneho hokejistu k uznávanému trénerovi.Bývalý hráč Slovana a mládežnícky reprezentant Matej Múčka odhalil, ako ho zranenia prinútili prehodnotiť kariéru a ako sa napokon našiel v trénerskej profesii. „Začínal som v Česku na trénerských kempoch, kde ma prekvapilo, že deti mali dva tréningy denne a na oboch ani nevideli puk,” spomínal na svoje trénerské začiatky v Karlových Varoch, kde spoznal úplne iný prístup k hokejovej príprave.V rozhovore spoznáte aj pikantné detaily z tréningov hviezdnych profíkov, ktorí sa pod jeho vedením pripravujú v lete. „Martin Fehérváry príde a ihneď prvé, čo povie: ‚Dobre, o 5 eur!' Pavol Regenda zas miluje súťaže a doťahovačky,” usmieva sa pri spomienke na súťaživosť profesionálov, ktorí si neodpustia ani tie najmenšie stávky.Nezabudnuteľné sú spomienky Mateja Múčku na MS v hokeji do 18 rokov v Rusku, kde bol súčasťou generácie s Marekom Viedenským či Martinom Štajnochom. „Išli sme do oslabenia, vyhodili sme puk, Rišo Pánik uletel a gól na 1:0. To bola eufória!” zaspomínal si na zápas proti Rusku.Ešte väčší priestor venoval historke o trénerovi Milanovi Stašovi, ktorý na letisku nabíjal svoj telefón cez zásuvku pri obrovskom vianočnom stromčeku a spôsobil výpadok elektriny.Matej Múčka otvorene rozprával aj o svojej trénerskej filozofii. „Chcem byť pre deti autorita, ale aj kamarát a vzor. Snažím sa im ukázať každý cvik, aby videli, že sa to dá,” vysvetľuje s tým, že ho teší, keď u svojich zverencov vidí progres. Jeho ambíciou je posunúť sa do profi hokeja a pracovať aj s reprezentáciou.V zábavnej a inšpiratívnej najnovšej epizóde podcastu suSPEAK na ŠPORT.sk sa dozviete veľa nielen o hokejových zručnostiach, ale aj o tom, ako skúsenosť z I. ligy v Topoľčanoch, kde praváci hrali III. tretinu s ľavačkami, formovala cestu Mateja Múčku k vrcholovému trénerskému remeslu.
Is the universe conspiring to bring us what we want in our lives? Probably not! Are we able to focus our attention so that we notice previously unnoticed objects and information. Most certainly! Does the Reticular Activating System guide our attention to the elements that are important for our lives. Contrary to popular opinion, absolutely not! In this episode Tom airs his frustrations about an often referred to part of the brain called the Ascending Reticular Activating System, or the RAS for short. This brain region that sits in the brain stem does have an important function when it comes to attention, but it's often interpreted as a completely different function. We discuss the RAS, what it actually does for us and what people tend to suggest that it is doing, even though the neuroscience doesn't back this up. Tom loves a juicy bit of neuroscience, but does become slightly irritated by neuro-nonsense, so likes to set the record straight where he can. Join us for this fascinating exploration of an important part of the brain, its function and the myth that is attributed to it. Enjoy the podcast? If you're enjoying the podcast it would be great if you left us a review here or wherever you listen to your podcast. Contact Details Find out about our Doctors' Transformational Coaching Diploma Connect with the hosts: Tom: www.linkedin.com/in/tomdillondoctorstranformationalcoachingdiploma/ Email: tomdillon@yourcoachingjourney.co.uk Helen: www.linkedin.com/in/helenleathers/ Email: helenleathers@yourcoachingjourney.co.uk Follow ‘Your Coaching Journey' on Instagram or Linkedin: www.instagram.com/yourcoachingjourney/ www.linkedin.com/company/your-coaching-journey/ Do You Have a Question? From time to time we will have an episode where we answer listeners' questions about coaching. If you have a question, please send it to us using one of our email addresses above and you may get a mention in a future episode. (If you want to remain anonymous, that's absolutely fine, just let us know)
Have you ever wondered why once you start thinking about something — a new car, a speaking opportunity, or even a business idea — suddenly, you seem to see it everywhere? That's not coincidence. It's your Reticular Activating System (RAS) at work. In this episode of Intuition Unleashed: A Revolution in Personal Liberation, I sit down with Joyce Layman, speaker, coach, TEDx presenter, and visibility strategist, to explore the powerful intersection of RAS, intuition, and strategy. Together, we dive into how to recognize the nudges, synchronicities, and hidden opportunities that are already around you — and how to align them with strategy so you can finally act. What You'll Learn in This Episode RAS explained in plain language — what it is and how it influences your perception.Why intuition is more than a hunch — and how to recognize when to trust it.How synchronicity works in real life — stories of “impossible” connections and doors opening at the right time.The role of strategy — why intuition and synchronicity only create results when paired with practical action. How to train your brain to spot opportunities you may have been missing all along.
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Ras Vanderloo recently retired after his 14th season as the Head Boys Basketball Coach at Sioux City East High School in Sioux City, IA. He spent 32 years coaching basketball, 14 as a Head Coach and 18 as an Assistant Coach. Ras is a 5-time district coach of the year and the 2017 State 4A Coach of the Year. He won 314 games as a head coach at East High with 4 State Tournament appearances and a State Runner Up in 2012.In addition to his run as the Head Coach at East, Ras also runs a large youth league basketball program with over 650 kids annually participating. The league is currently 33 years old and was started by his father.Ras comes from a large coaching family, his father Rich and brother Jeff (now a Creighton Assistant) are both former Head Coaches at East High in Sioux City. His brothers John and Jim are coaches as wellRas has worked with USA Basketball in varying capacities, most recently as an assistant coach for the Men's 3 x 3 Nation's League that competed this summer in Chile. On this episode Mike & Ras discuss his retirement from teaching and coaching along with the new opportunities in front of him, including his involvement with USA Basketball. Vanderloo reflects on the significance of learning from experienced mentors and emphasizes the value of dedication and hard work in achieving success in coaching. He shares insights about the differences between coaching in traditional formats versus the increasingly popular 3x3 basketball format, highlighting the unique challenges and strategies involved in this fast-paced version of the game. Additionally, Vanderloo provides practical advice for young coaches, advocating for the importance of seeking out successful programs and experienced coaches to learn from. As he navigates his post-retirement journey, he remains committed to contributing to the basketball community and mentoring future generations of coaches.Follow us on Twitter and Instagram @hoopheadspod for the latest updates on episodes, guests, and events from the Hoop Heads Pod.Make sure you're subscribed to the Hoop Heads Pod on your favorite podcast app and while you're there please leave us a 5 star rating and review. Your ratings help your friends and coaching colleagues find the show. If you really love what you're hearing recommend the Hoop Heads Pod to someone and get them to join you as a part of Hoop Heads Nation.Get ready to take some notes as you listen to this episode with Ras Vanderloo from Sioux City East High School in the state of Iowa.Website – https://www.usab.com/staff-members/ras-vanderlooEmail – rvanderloo6562@gmail.comTwitter - @CoachRasVisit our Sponsors!Dr. Dish BasketballOur friends at Dr. Dish Basketball are here to help you transform your team's training this off-season with exclusive offers of up to $4,000 OFF their Rebel+, All-Star+, and CT+ shooting machines. Unsure about budget? Dr. Dish offers schools-only Buy Now, Pay Later payment plans to make getting new equipment easier than ever.The Coaching PortfolioYour first impression is everything...
Welcome to the The Achievers Podcast. I'm your host, Amber Deibert, Performance Coach. I help enterprise sellers unlock their full potential by aligning their work with how they work and cleaning up mindset trash, so they can sell more, stress less, and take back control of their time and success. Do you cringe when someone asks, “Where do you see yourself in five years?” Most achievers love the idea of having a plan but freeze up trying to make one. In this episode, Amber walks you through a simple, values-based process to design a 5- and 10-year plan you'll actually stick with. No overwhelm, no overthinking… just clarity, direction, and next steps.
Send us a textIf your brain was a nightclub... who the hell have you been letting in?In this week's Reinvention Era episode, we're ditching the hustle and rewriting the guest list.You'll meet your brain's inner staff…. from the flyer girl (RAS) to the bouncer (Amygdala) to HR (Hypothalamus), AND learn how to retrain your nervous system to roll out the velvet rope for badass boldness, wealth, power, and your next-era identity.This isn't “positive thinking”It's nervous system strategy.It's identity design.It's VIP-level reinvention.Oh…. and if wealth is on your new guest list?We're kicking off Rich AF by Amanda Frances inside the Badass AF Book Club starting September 1st.Rich As F*ck on Amazon UK*Join us and start making your next era rich in every sense of the word.Book starts September 1st.Guest list is open. You're already on it.Loads of LoveSarah x
V najnovšej epizóde populárneho hokejového podcastu suSPEAK sa Rasťo Konečný a Marek Marušiak porozprávali s obrancom HK Nitra Martinom Vitalošom, ktorý patrí medzi najtvrdších hráčov našej extraligy.Nitriansky hokejista, ktorý je držiteľom rekordu za najviac bodyčekov v našej najvyššej súťaži, sa v rozhovore otvorene rozhovoril o svojej kariére a životných skúsenostiach. Martin Vitaloš prezradil, ako sa ružinovský odchovanec dostal cez Slovan až do švédskeho klubu Rögle, kde strávil dve sezóny.Diváci sa dozvedia zaujímavé a miestami humorné príbehy z jeho pobytu vo Švédsku vrátane ochutnávky surströmmingu (fermentovanej ryby), ktorá sa skončila nepríjemnou skúsenosťou, ale aj pozitívne momenty zo švédskej hokejovej kultúry. Martin Vitaloš tiež otvorene porozprával o náročnej epizóde v českej Plzni, kde nemal takmer žiadny priestor na ľade a dokonca ho poslali hrať za Klatovy do tretej najvyššej súťaže.Rozhovor postupne prešiel k jeho najväčšiemu kariérnemu úspechu - zisku majstrovského titulu s Nitrou, kde si zaspomínal na kľúčový moment sezóny a následné oslavy. Martin Vitaloš tiež zaznačil svoje plány do budúcnosti vrátane ambícií zahrať si opäť v zahraničí, ale odhalil aj prekvapivé štúdium diplomacie ako prípravu na život po hokejovej kariére.V uvoľnenej atmosfére plnej vtipných momentov sa dozviete, prečo sa tento tvrdý obranca stal postrachom útočníkov v našej extralige, aký typ bodyčekov preferuje a aká je jeho hokejová filozofia.Táto epizóda ponúka výnimočný pohľad do života jedného z najvýraznejších hráčov slovenskej extraligy, ktorý otvorene rozprával o vzostupoch aj pádoch svojej hokejovej kariéry.
Sarah Biskowitz and Ruby Zuckerman joined "The Shmooze" to talk about the Great Jewish Books Summer Program. Sarah and Ruby, alums of the program, are back at the Yiddish Book Center as RAs for this year's program. In conversation we talk about their experiences as participants and as RAs and learn about how Great Jewish Books lead them in new directions, personal and professional. And we hear what's on the reading list for this summer's students. Episode 395 August 7, 2025 Amherst, MA
How can we prevent our older adults with prediabetes from developing diabetes? Susan is a board certified health and wellness coach. She is a certified with the CDC diabetes prevention program and owner of Weighting4You. She will walk us through the use of continuous glucose monitors (CGMs) to assist with lowering HgbA1c, counseling tips for patients on GLP-1 RAs, and more. I hope you enjoy our conversation. The Geriatric Pharmacy Focus podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Connect with Tamara here: www.linkedin.com/in/tamara-ruggles-491882251 www.thedeprescribingclinic.com Connect with Susan here:linkedin.com/in/susanward https://weighting4you.com/
Grandpa Bill Asks: listeners, picture this: We're standing with Dr. Metivier inside the early structure of his physical Memory Palace in Australia. Sunlight streams through the unglazed windows, illuminating the concrete floor where the A-to-Z memory wheel will soon be. In the center of this space, Dr. Metivier stands with his real bass guitar.Now, let's use the Major System to create a memorable scene of him playing multiple Bach works, associating each number with a specific action or element related to a piece.0 - S/Z/Soft C: Imagine Dr. Metivier zipping up a black leather jacket as he prepares to play the opening of Bach's Toccata and Fugue in D minor (often adapted for bass). The 'zipping' sound and the dramatic nature of the piece connect to the 'S' sound of zero.1 - T/Th: He then begins the famous Air on the G String from Orchestral Suite No. 3. Imagine him gently tapping his foot in time with the melody. The 'T' sound links to the number one and the flowing, gentle nature of the piece.2 - N: Next, he transitions to a lively section from one of the Brandenburg Concertos. Visualize a flock of gnats buzzing around his head as he plays a particularly intricate and fast passage, representing the quick, busy nature of the music. The 'N' sound connects to the number two.3 - M: For the powerful Passacaglia and Fugue in C minor, imagine a giant ham swinging rhythmically in front of him as he plays the deep, grounding bass line of the Passacaglia. The 'M' sound links to three, and the weighty image reflects the music's gravitas.4 - R: As he moves to a movement from one of the Cello Suites, picture a rower in a small boat gently rocking back and forth in time with the bowing motions his right hand makes on the bass strings. The 'R' sound connects to four and evokes the smooth, flowing quality of the cello.5 - L: Imagine a bright light suddenly illuminating the fretboard as he plays a particularly beautiful and soaring melodic line from the Mass in B minor (again, a bass adaptation). The 'L' sound connects to five and emphasizes the radiant quality of the music.6 - J/Sh/Ch/Soft G: For an adaptation of one of the English Suites, see him suddenly wearing a chef's hat and playfully conducting with his head while he plays a more dance-like and rhythmic section. The 'Ch' sound connects to six and adds a whimsical element.8 - F/V: As he plays a section from the Goldberg Variations (arranged for bass), imagine fluffy white foam suddenly erupting from the sound holes in his bass, bubbling and dissipating with the intricate variations. The 'F' sound connects to eight and provides a visual texture to the complex music.9 - P/B: Finally, for a powerful cadence, imagine a large purple balloon inflating and then gently deflating in time with the final, resonant notes of a Bach Chorale. The 'P/B' sounds connect to nine and provide a strong visual conclusion.So, there you have it, Dr. Metivier in his future Memory Palace, playing a medley of Bach, with each piece and a corresponding Major System number brought to life through a vivid mnemonic image. This is the power of the Magnetic Memory Method in action, connecting sound, image, and location in a truly unforgettable way. Dr. Metivier will be on my Podcast on 8/12/25 WE will discuss his thoughts on this at that time stay tuned!#BachOnBass,#MajorSystem,#MnemonicMusic,#PhysicalMemoryPalace,#Dr.AnthonyMetivier#MagneticMemoryMethod,#Bach,#MemoryPalace,#GrandpaBill,#BHSalesKennelKelpHolisticHealingHour,Join us at The BH Sales Kennel Kelp Holistic Healing Hour Podcast Daily and YouTube @billholt8792
10 - Imam Sadi's explanation of Jawaami' Al-Akhbaar | Abu Abdir-Rahmān Hilāl - Manchester Explanation of Shaykh Ubayd al-jaabiree Abū Hurayrah (raḍī Allāhu ʿanhu) said: Rasūlullah (ﷺ) said: Allāh does not accept the Prayer of anyone of you who has nullified his purification until he makes wuḍū. Narrated by Bukhari & Muslim Live at the Salafi Centre of Manchester on 2/8/25
The Positivity & Prosperity Podcast | Mindset | Entrepreneurship | Law of attraction | Manifesting |
Feeling stuck in the manifestation gap — that frustrating space where your desires haven't arrived yet? In this episode, we're diving into why the delay doesn't mean it's not working, how to shift your mindset when you start to doubt, and what your brain is doing behind the scenes to filter your reality.You'll learn:Why the absence of evidence isn't evidence of absence (thank you, Price Pritchett).The iceberg model of manifestation (Freud meets manifestation).How your Reticular Activating System can either help or sabotage your manifestation.Why surrender is the secret to speeding things up.How to keep your signal clean, stay in alignment, and hold the vibe — even when nothing is showing up… yet.
V najnovšej epizóde podcastu suSPEAK na ŠPORT.sk privítali moderátori Marek Marušiak a Rasťo Konečný jednu z najväčších streleckých osobností slovenskej extraligy Romana Tománka. Takmer 40-ročný rodák z malebného Milochova v Považskej Bystrici sa otvorene rozhovoril o svojej bohatej kariére aj prešľapoch, ktoré ju ovplyvnili.Charizmatický útočník, ktorý bol v roku 2004 draftovaný Phoenixom Coyotes v rovnakom ročníku ako Alexander Ovečkin či Jevgenij Malkin, sa v rozhovore vrátil k hokejovým začiatkom. Ako chlapec, ktorého hokej bavil nielen na štadióne, ale aj mimo neho - či už pri vytváraní hokejok z čísel autobusov, alebo zo zemiakových vriec.Roman Tománek bol najlepším strelcom majstrovstiev sveta do 18 rokov, o prvenstvo sa delil s Philom Kesselom. Napriek talentu však v rozhovore priznáva, že vtedy ani nevedel, čo draft znamená.V najnovšej epizóde podcastu suSPEAK na ŠPORT.sk sa dozviete detaily aj o premiére Romana Tománka v kempe Phoenixu, kde neveril vlastným očiam, keď ho trénoval Wayne Gretzky. Rovnako úprimne porozprával aj o svojom pôsobení v zahraničí - od divokých zážitkov v Kazachstane, kde zažil cestu po púšti a aj ulomené koleso, až po nemeckú precíznosť v Rostocku.Fanúšikovia slovenského hokeja si určite vychutnajú spomienky na pôsobenie v Nitre, kde vytvoril obávané ofenzívne duo s Jozefom Stümpelom. Hovoril aj o tom, že v jednej sezóne mal po desiatom zápase 0+0, no nakoniec skončili s vyše 70 bodmi. Roman Tománek má na konte viac ako 40-gólovú sezónu v extralige a patrí k hokejistom, ktorým chýba vo vitríne len slovenský titul. Dvakrát sa dostal do finále - najprv s Nitrou, potom s Banskou Bystricou, vždy však ťahal za kratší koniec.V rozhovore si zaspomína na „staré časy” aj Rasťo Konečný, ktorý s Romanom Tománkom zdieľal spoločný ľad, a prezradil, ako vyzerali ich spoločné rozcvičky: „‚Gejzo' si zobral puk, ‚prešmotlal' a vystrelil. A my dvaja mu hovoríme, že by sme si mohli ten puk ešte vymeniť. A Gejzo: ‚Sorry, chalani. Ja si skúšam'.”Skúsený útočník, ktorý síce dnes stále hrá, ale zároveň už aj trénuje mládež v Považskej Bystrici, sa zamyslel aj nad pokračovaním svojej aktívnej kariéry: „V mojom veku je to v tomto smere už také, že ak to nebude mať význam, ani hlavu, ani pätu, tak to jednoducho ukončím.”Rozhovor uzatvoril úprimným odkazom mladým hokejistom, v ktorom upozornil, že jeho príbeh je príkladom toho, ako môžu byť blízko k rozprávkovej kariére, ale zároveň od nej aj ďaleko. Zdôraznil, že talent nestačí, dôležitá je drina a schopnosť požiadať v ťažkých chvíľach o pomoc.
On this episode of ResEdChat, join our host Noah Montague, and guest Mathew Perry, Resident Director at Miami University of Ohio, to talk about RA recruitment. RA recruitment is one of the biggest endeavors that any Residence Life department goes through. And naturally, there are always things that go well and things that can go better. Noah and Perry discuss tangible ways to better recruit RAs and make the processes more equitable for those in them.
The incidence of early onset colorectal cancer (EOCRC) has been rising prompting the change in change in screening guidelines to 45 years of age for average risk patients. Join us for an in-depth discussion with guest speakers Dr. Andrea Cercek and Dr. Nancy You, where we provide a comprehensive look at the growing challenge of EOCRC. Hosts: - Dr. Janet Alvarez - General Surgery Resident at New York Medical College/Metropolitan Hospital Center - Dr. Wini Zambare – General Surgery Resident at Weill Cornell Medical Center/New York Presbyterian - Dr. Phil Bauer, Graduating Colorectal Surgical Oncology Fellow at Memorial Sloan Kettering Cancer Center - Dr. J. Joshua Smith MD, PhD, Chair, Department of Colon and Rectal Surgery at MD Anderson Cancer Center - Dr. Andrea Cercek - Gastrointestinal Medical Oncologist at Memorial Sloan Kettering Cancer Center - Dr. Y. Nancy You, MD MHSc - Professor, Department of Colon and Rectal Surgery at MD Anderson Cancer Center Learning objectives: - Describe trends in incidence of colorectal cancer, with emphasis on the rise of EOCRC. - Identify age groups and demographics most affected by EOCRC. - Summarize USPSTF recommendations for colorectal cancer screening. - Distinguish between screening methods (e.g., colonoscopy, FIT-DNA) and their sensitivity. - Understand treatment approaches for colon and rectal cancer (CRC) - Understand the role of mismatch repair (MMR) status in guiding treatment. - Outline the importance of genetic counseling and testing in young patients. - Discuss racial, ethnic, and socioeconomic disparities in CRC incidence and outcomes. - Describe the impact of cancer treatment on fertility and sexual health. - Review fertility preservation options. - Identify the value of integrated care teams for young CRC patients. References: 1. Siegel, R. L. et al. Colorectal Cancer Incidence Patterns in the United States, 1974–2013. JNCI J. Natl. Cancer Inst. 109, djw322 (2017). https://pubmed.ncbi.nlm.nih.gov/28376186/ 2. Abboud, Y. et al. Rising Incidence and Mortality of Early-Onset Colorectal Cancer in Young Cohorts Associated with Delayed Diagnosis. Cancers 17, 1500 (2025). https://pubmed.ncbi.nlm.nih.gov/40361427/ 3. Phang, R. et al. Is the Incidence of Early-Onset Adenocarcinomas in Aotearoa New Zealand Increasing? Asia Pac. J. Clin. Oncol.https://pubmed.ncbi.nlm.nih.gov/40384533/ 4. Vitaloni, M. et al. Clinical challenges and patient experiences in early-onset colorectal cancer: insights from seven European countries. BMC Gastroenterol. 25, 378 (2025). https://pubmed.ncbi.nlm.nih.gov/40375142/ 5. Siegel, R. L. et al. Global patterns and trends in colorectal cancer incidence in young adults. (2019) doi:10.1136/gutjnl-2019-319511. https://pubmed.ncbi.nlm.nih.gov/31488504/ 6. Cercek, A. et al. A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers. J. Natl. Cancer Inst. 113, 1683–1692 (2021). https://pubmed.ncbi.nlm.nih.gov/34405229/ 7. Zheng, X. et al. Comprehensive Assessment of Diet Quality and Risk of Precursors of Early-Onset Colorectal Cancer. JNCI J. Natl. Cancer Inst. 113, 543–552 (2021). https://pubmed.ncbi.nlm.nih.gov/33136160/ 8. Standl, E. & Schnell, O. Increased Risk of Cancer—An Integral Component of the Cardio–Renal–Metabolic Disease Cluster and Its Management. Cells 14, 564 (2025). https://pubmed.ncbi.nlm.nih.gov/40277890/ 9. Muller, C., Ihionkhan, E., Stoffel, E. M. & Kupfer, S. S. Disparities in Early-Onset Colorectal Cancer. Cells 10, 1018 (2021). https://pubmed.ncbi.nlm.nih.gov/33925893/ 10. US Preventive Services Task Force. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA 325, 1965–1977 (2021). https://pubmed.ncbi.nlm.nih.gov/34003218/ 11. Fwelo, P. et al. Differential Colorectal Cancer Mortality Across Racial and Ethnic Groups: Impact of Socioeconomic Status, Clinicopathology, and Treatment-Related Factors. Cancer Med. 14, e70612 (2025). https://pubmed.ncbi.nlm.nih.gov/40040375/ 12. Lansdorp-Vogelaar, I. et al. Contribution of Screening and Survival Differences to Racial Disparities in Colorectal Cancer Rates. Cancer Epidemiol. Biomarkers Prev. 21, 728–736 (2012). https://pubmed.ncbi.nlm.nih.gov/22514249/ 13. Ko, T. M. et al. Low neighborhood socioeconomic status is associated with poor outcomes in young adults with colorectal cancer. Surgery 176, 626–632 (2024). https://pubmed.ncbi.nlm.nih.gov/38972769/ 14. Siegel, R. L., Wagle, N. S., Cercek, A., Smith, R. A. & Jemal, A. Colorectal cancer statistics, 2023. CA. Cancer J. Clin. 73, 233–254 (2023). https://pubmed.ncbi.nlm.nih.gov/36856579/ 15. Jain, S., Maque, J., Galoosian, A., Osuna-Garcia, A. & May, F. P. Optimal Strategies for Colorectal Cancer Screening. Curr. Treat. Options Oncol. 23, 474–493 (2022). https://pubmed.ncbi.nlm.nih.gov/35316477/ 16. Zauber, A. G. The Impact of Screening on Colorectal Cancer Mortality and Incidence: Has It Really Made a Difference? Dig. Dis. Sci. 60, 681–691 (2015). https://pubmed.ncbi.nlm.nih.gov/25740556/ 17. Edwards, B. K. et al. Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 116, 544–573 (2010). https://pubmed.ncbi.nlm.nih.gov/19998273/ 18. Cercek, A. et al. Nonoperative Management of Mismatch Repair–Deficient Tumors. New England Journal of Medicine 392, 2297–2308 (2025). https://pubmed.ncbi.nlm.nih.gov/40293177/ 19. Monge, C., Waldrup, B., Carranza, F. G. & Velazquez-Villarreal, E. Molecular Heterogeneity in Early-Onset Colorectal Cancer: Pathway-Specific Insights in High-Risk Populations. Cancers 17, 1325 (2025). https://pubmed.ncbi.nlm.nih.gov/40282501/ 20. Monge, C., Waldrup, B., Carranza, F. G. & Velazquez-Villarreal, E. Ethnicity-Specific Molecular Alterations in MAPK and JAK/STAT Pathways in Early-Onset Colorectal Cancer. Cancers 17, 1093 (2025). https://pubmed.ncbi.nlm.nih.gov/40227607/ 21. Benson, A. B. et al. Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. J. Natl. Compr. Cancer Netw. JNCCN 19, 329–359 (2021). https://pubmed.ncbi.nlm.nih.gov/33724754/ 22. Christenson, E. S. et al. Nivolumab and Relatlimab for the treatment of patients with unresectable or metastatic mismatch repair proficient colorectal cancer. https://pubmed.ncbi.nlm.nih.gov/40388545/ 23. Dasari, A. et al. Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study. The Lancet 402, 41–53 (2023). https://pubmed.ncbi.nlm.nih.gov/37331369/ 24. Strickler, J. H. et al. Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study. Lancet Oncol. 24, 496–508 (2023). https://pubmed.ncbi.nlm.nih.gov/37142372/ 25. Sauer, R. et al. Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer. N. Engl. J. Med. 351, 1731–1740 (2004). https://pubmed.ncbi.nlm.nih.gov/15496622/ 26. Cercek, A. et al. Adoption of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer. JAMA Oncol. 4, e180071 (2018). https://pubmed.ncbi.nlm.nih.gov/29566109/ 27. Garcia-Aguilar, J. et al. Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy. J. Clin. Oncol. 40, 2546–2556 (2022). https://pubmed.ncbi.nlm.nih.gov/35483010/ 28. Schrag, D. et al. Preoperative Treatment of Locally Advanced Rectal Cancer. N. Engl. J. Med. 389, 322–334 (2023). https://pubmed.ncbi.nlm.nih.gov/37272534/ 29. Kunkler, I. H., Williams, L. J., Jack, W. J. L., Cameron, D. A. & Dixon, J. M. Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer. N. Engl. J. Med. 388, 585–594 (2023). https://pubmed.ncbi.nlm.nih.gov/36791159/ 30. Jacobsen, R. L., Macpherson, C. F., Pflugeisen, B. M. & Johnson, R. H. Care Experience, by Site of Care, for Adolescents and Young Adults With Cancer. JCO Oncol. Pract. (2021) doi:10.1200/OP.20.00840. https://pubmed.ncbi.nlm.nih.gov/33566700/ 31. Ruddy, K. J. et al. Prospective Study of Fertility Concerns and Preservation Strategies in Young Women With Breast Cancer. J. Clin. Oncol. (2014) doi:10.1200/JCO.2013.52.8877. https://pubmed.ncbi.nlm.nih.gov/24567428/ 32. Su, H. I. et al. Fertility Preservation in People With Cancer: ASCO Guideline Update. J. Clin. Oncol. 43, 1488–1515 (2025). https://pubmed.ncbi.nlm.nih.gov/40106739/ 33. Smith, K. L., Gracia, C., Sokalska, A. & Moore, H. Advances in Fertility Preservation for Young Women With Cancer. Am. Soc. Clin. Oncol. Educ. Book 27–37 (2018) doi:10.1200/EDBK_208301. https://pubmed.ncbi.nlm.nih.gov/30231357/ 34. Blumenfeld, Z. How to Preserve Fertility in Young Women Exposed to Chemotherapy? The Role of GnRH Agonist Cotreatment in Addition to Cryopreservation of Embrya, Oocytes, or Ovaries. The Oncologist 12, 1044–1054 (2007). 35. Bhagavath, B. The current and future state of surgery in reproductive endocrinology. Curr. Opin. Obstet. Gynecol. 34, 164 (2022). 36. Ribeiro, R. et al. Uterine transposition: technique and a case report. Fertil. Steril. 108, 320-324.e1 (2017). 37. Yazdani, A., Sweterlitsch, K. M., Kim, H., Flyckt, R. L. & Christianson, M. S. Surgical Innovations to Protect Fertility from Oncologic Pelvic Radiation Therapy: Ovarian Transposition and Uterine Fixation. J. Clin. Med. 13, 5577 (2024). 38. Holowatyj, A. N., Eng, C. & Lewis, M. A. Incorporating Reproductive Health in the Clinical Management of Early-Onset Colorectal Cancer. JCO Oncol. Pract. 18, 169–172 (2022). ***Behind the Knife Colorectal Surgery Oral Board Audio Review: https://app.behindtheknife.org/course-details/colorectal-surgery-oral-board-audio-review Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our recent episodes here: https://app.behindtheknife.org/listen
SummaryIn this episode of A Cup of Joe podcast, Joe Morton explores the interconnectedness of the reticular activating system (RAS) and the law of attraction, emphasizing the power of thoughts, emotions, and intentions in shaping our reality. He discusses how our beliefs and dominant thoughts filter our experiences and attract corresponding outcomes. The conversation delves into practical applications such as prayer, visualization, and mindfulness, highlighting the importance of setting intentions and nurturing a positive mindset to achieve personal goals and well-being. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit joemorton88.substack.com
MUSICDeftones will release their first album in five years, Private Music, on August 22nd. The first single is called "My Mind Is a Mountain," which you can check out on YouTube now. The album was produced by Nick Raskulinecz [pr: RAS-kell-in-ich], who sat in the producer's chair on 2010's Diamond Eyes and 2012's Koi No Yokan. https://www.youtube.com/watch?v=cgh_jEm5twE An old clip is resurfacing again from the Joe Rogan podcast where Jelly Roll sets some things straight. A bunch of people on the internet were calling his wife, Bunnie XO, a gold digger for being with him . . . but Jelly had the perfect answer. https://www.tiktok.com/@xomgitsbunnie/video/7234363257467817259 Jojo Siwa has teased a cover of Kim Carnes' classic '80s hit "Bette Davis Eyes", and Kim dissed it on an Instagram post that has since been deleted. Kim said "There's a difference between singing a song . . . And embodying it." Here's the clip Jojo posted. https://pagesix.com/2025/07/10/entertainment/kim-carnes-seemingly-shades-jojo-siwas-viral-betty-davis-eyes-cover/? The Yungblud documentary Are You Ready Boy? will be shown in theaters on August 20th and 24th. https://yungblud.film/ Ozzy Osbourne teamed up with some chimpanzees to create five paintings to sell at an auction to raise money for Save the Chimps. He says, quote, "I paint because it gives me peace of mind, but I don't sell my paintings. I've made an exception with these collaborations as it raises money for Save the Chimps . . . NEW ALBUM RELEASES:311 - 311 30th Anniversary Edition (two-LP set)Wet Leg - Moisturizer TVRick Springfield was disrespected not once, but TWICE on the "Today" show yesterday. The first diss happened before he even came out on the set. Al Roker was hyping Rick's appearance, and fellow hosts Savannah Guthrie, Jenna Bush Hager, and Kaylee Hartung started singing "867-5309 / Jenny". As EVERYONE should know, that's NOT a Rick Springfield song. It's by the FAR INFERIOR Tommy Tutone. https://www.dailymail.co.uk/media/article-14893911/today-rick-springfield-hosts-yawned-craig-melvin.html Check out a new trailer for the "King of the Hill" revival. https://www.hollywoodreporter.com/tv/tv-news/king-of-the-hill-revival-trailer-hulu-1236311177/ Larry David is returning to HBO one more time for a limited sketch comedy series about American history. David will star in six episodes. https://variety.com/2025/tv/news/larry-david-american-history-sketch-comedy-series-hbo-1236451946/ Tom Brady's representative has firmly denied claims that he ever said Sofía Vergara is “too old” to date him, calling such reports “pure fiction” and saying he “would never” make such a remark, according to People magazine. https://people.com/tom-brady-would-never-say-sofia-vergara-too-old-date-says-rep-exclusive-11770067?utm_source=chatgpt.com MOVING ON INTO MOVIE NEWS: IN THEATERS:Superman (Nicholas Hoult, Rachel Brosnahan, David Corenswet) The third installment of the 'Dune' franchise has an official title, 'Dune: Part Three.' Rumors spread that the movie would be called 'Dune Messiah', based off of the 1969 novel. https://variety.com/2025/film/news/dune-3-title-imax-cameras-1236448953/ AND FINALLYBefore some celebrities made it BIG, they did background work for movies, TV, and even music videos. BuzzFeed put together a list of some of these familiar faces. https://www.buzzfeed.com/trendyghost618/celebrities-who-started-as-extras AND THAT IS YOUR CRAP ON CELEBRITIES!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:https://www.mycme.com/courses/the-latest-data-in-ckd-progression-10197SummaryEmerging evidence highlights the potential of GLP-1 receptor agonists (GLP-1 RAs) to slow CKD progression and reduce cardiovascular and kidney-related mortality in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD). Yet, despite updated guidelines, these therapies remain underused. This program will explore the latest clinical data supporting the role of GLP-1 RAs in risk mitigation and provide practical strategies for implementing guideline-based treatment to reduce cardio-renal risk and improve outcomes in patients with T2D and CKD.This podcast was recorded and is being used with permission of the presenters.Learning ObjectivesAt the conclusion of this activity, participants should be better able to:Discuss emerging data on GLP-1 RA therapy for CKD progression in T2DImplement guideline-based care to minimize CV risk and CKD progressionThis activity is accredited for CME/CE CreditThe National Association for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.The National Association for Continuing Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.The National Association for Continuing Education is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 121222. This activity is approved for 0.25 contact hours (which includes 0.25 hours of pharmacology).For additional information about the accreditation of this program, please contact NACE at info@naceonline.com.Summary of Individual DisclosuresPlease review faculty and planner disclosures here.Disclosure of Commercial SupportThis activity is supported by an educational grant from Novo Nordisk.Please visit http://naceonline.com to engage in more live and on demand CME/CE content.
Azra Sokira je mladá slovenská influencerka s výrazným balkánskym temperamentom. Ten ju zviditeľnil nielen na Farme, ale aj v tretej sérii reality šou Ruža pre nevestu. Vyspovedali sme ju v StarTalks s Ninou. V podcaste sa dozviete: Ako Azru vnímajú ľudia po skončení Ruže pre nevestu? Išla do šou hľadať lásku, alebo sa iba zviditeľniť? Ktorá séria mala podľa nej najlepšieho ženícha a vydržalo by to Azre s Rasťom aj v reálnom živote? S ktorými ružičkami si najviac a naopak najmenej rozumela a ktorú si na sociálnych sieťach zablokovala? Ako vzala fakt, že Miška na ňu pred Rasťom vytiahla, že mala na Farme sex na kamerách? Je nejaká situácia z Ruže, ktorú spätne ľutuje? Prečo drží svojho priateľa mimo záujmu médií a čo on hovorí na jej účinkovanie v Ruži? Taktiež budete počuť: Tolerovala by Azra u muža, keby sledoval na instagrame svoje ex? Akceptovala by, ak by bol muž nižší než ona? Ako by vnímala, ak by muž stále býval u matky a nevedel variť?
This is a rerelease of one of our popular episodes from our series on ballet summer intensives. Wondering how much the RAs see of student antics? More than you think! We're talking with Robert Fulton and Camille Kellems, both professional dancers and also RAs at ballet summer intensives. Get ready for a mix of insider info that's helpful for parents as well as hilarious anecdotes as Robert and Camille let us in on what really goes on behind the scenes. From dorm shenanigans to studio mishaps, they've seen it all and they're here to spill the tea. Robert and Camille are also the founders of Ballet Scout. You can learn more about what they do on their website. Links: Support Ballet Help Desk Summer Intensive Essentials Guide Buy Summer Corrections Journals Instagram: @BalletHelpDesk Facebook: BalletHelpDesk Ballet Help Desk Music from #Uppbeat: https://uppbeat.io/t/ian-aisling/new-future License code: MGAW5PAHYEYDQZCI
Ras de tierra con Ana Laura Magaloni
30 Jun 2025. Air Asia aims to open a Gulf hub this year with four airports on the shortlist, including Ras al Khaimah. CEO Tony Fernandes shares the details. Plus, we get the inside story on G42’s rise to the global Top 100 - the company’s chief marketing officer joins us live. And with the UAE corporate tax deadline fast approaching, tax expert Vishal Sharma joins us to explain what businesses need to know and what exemptions may still apply.See omnystudio.com/listener for privacy information.
What if your brain has a built-in filtration system that's keeping you stuck in worry instead of manifesting your dreams? In this special bonus episode of Why Isn't Everyone Doing This?, I'm taking you deep into the science behind embodied manifesting and revealing why traditional manifestation techniques often fall short. Most people spend minutes every day "worshiping their worries"—obsessing over what could go wrong instead of focusing on what they'd love to create. But there's actual neuroscience behind why this happens, and more importantly, how to rewire it. I break down the reticular activating system (RAS), your brain's filter that determines what you notice in reality. When you're in chronic stress, this filter prioritizes threats over opportunities. But when you learn to regulate your nervous system first, then manifest from that grounded state, everything changes.
Send us a textEver feel like you're juggling flaming swords on a tightrope over a pit of to-do lists?Whether it's surprise invoices, deadline-pinging texts, or a mind that spirals straight to worst-case scenario mode… this episode is for the high-achiever who's ever found herself red-faced and frozen mid-Zoom call, wondering, “How am I going to pull all this off?”Join Alex and Carol for a raw, practical, and encouraging conversation about what really happens in our minds and bodies when overwhelm hits—and what to do about it.
Sometimes we meet people and we tell them something about Kṛṣṇa, give them a book, and it's not immediately evident, but later, we'll meet them. Or maybe we won't meet them, we'll meet somebody else who had an incidental contact with the devotee, and then they'll tell how everything started from that one statement. “I heard that thing. He said this, I read this one thing, and then it started.” And we're in a liminal state. Any minute we can cross back over into the spiritual environment by a little encouragement from the sound vibration, or by the same principle, we can always slip into nescience. But once the devotees have been awakened and have experienced the taste of Kṛṣṇa consciousness, even if they temporarily slip into darkness, it's not the same, Nārada Muni says, “as it is for somebody who's never experienced it, they always remember it.” Even though they become captured by Māyā, they still remember. As Viśvanātha Cakravartī Ṭhākura said, they're haunted by the ghost of rasa. Rasāgraha, he said, “they're grabbed by it.” They keep thinking, “Oh, yeah, but I remember that time.” So it's very poignant, what you said about the power of the sound. And the saṅkīrtana movement is based on that; it's spreading that same sound vibration, Bhagavad-gītā, and the holy names to other living entities. ------------------------------------------------------------ To connect with His Grace Vaiśeṣika Dāsa, please visit https://www.fanthespark.com/next-steps/ask-vaisesika-dasa/ ------------------------------------------------------------ Add to your wisdom literature collection: https://iskconsv.com/book-store/ https://www.bbtacademic.com/books/ https://thefourquestionsbook.com/ ------------------------------------------------------------ Join us live on Facebook: https://www.facebook.com/FanTheSpark/ Podcasts: https://podcasts.apple.com/us/podcast/sound-bhakti/id1132423868 For the latest videos, subscribe https://www.youtube.com/@FanTheSpark For the latest in SoundCloud: https://soundcloud.com/fan-the-spark ------------------------------------------------------------ #spiritualawakening #soul #spiritualexperience #spiritualpurposeoflife #spiritualgrowthlessons #secretsofspirituality #vaisesikaprabhu #vaisesikadasa #vaisesikaprabhulectures #spirituality #bhaktiyoga #krishna #spiritualpurposeoflife #krishnaspirituality #spiritualusachannel #whybhaktiisimportant #whyspiritualityisimportant #vaisesika #spiritualconnection #thepowerofspiritualstudy #selfrealization #spirituallectures #spiritualstudy #spiritualquestions #spiritualquestionsanswered #trendingspiritualtopics #fanthespark #spiritualpowerofmeditation #spiritualteachersonyoutube #spiritualhabits #spiritualclarity #bhagavadgita #srimadbhagavatam #spiritualbeings #kttvg #keepthetranscendentalvibrationgoing #spiritualpurpose
GLP-1 receptor agonists have changed the landscape of obesity treatment, offering levels of weight loss once thought unattainable without surgery. But what happens after the weight is lost? And can we really talk about success without talking about maintenance? While much of the public discourse fixates on dramatic weight loss numbers, the harder question is what comes next. Can lifestyle interventions alone sustain weight loss after GLP-1 cessation? How do metabolic adaptations and behavioral relapse factor in? And what does the data actually show about relapse rates, nutritional adequacy, and lean mass preservation when using these medications? In this episode, Danny sits down with Tara Schmidt, dietitian at the Mayo Clinic, to examine the intersection of pharmacology and behavior in long-term weight management. Tara Schmidt is a registered dietitian and an instructor of nutrition at Mayo Clinic. As the lead dietitian for the Mayo Clinic Diet, she provides guidance rooted in evidence-based principles. She hosts the Mayo Clinic On Nutrition podcast and co-authored The Mayo Clinic Diet: Weight Loss Medications Edition. Timestamps [05:17] Understanding weight loss maintenance [08:44] Defining success in weight loss maintenance [11:54] Predictors of maintenance: self-monitoring and behavioral strategies [23:37] Pharmacological interventions: GLP-1 receptor agonists [31:06] Dietary considerations for those taking GLP-1 RAs [37:07] Addressing misconceptions about weight loss drugs [42:48] Final thoughts and takeaways [48:49] Key ideas (Premium-only) Links/Resources Subscribe to Sigma Nutrition Premium Go to episode page Join the Sigma email newsletter for free Enroll in the next cohort of our Applied Nutrition Literacy course Visit sigmanutrition.com
On this episode of The Wholesome Fertility Podcast, I am joined by Dr. Nirali Jain (eggspert_md), a board-certified OB/GYN and reproductive endocrinologist at Reproductive Medical Associates (RMA). Dr. Jain shares her expert insights on fertility preservation for individuals undergoing cancer treatment, a crucial yet often overlooked aspect of reproductive care. We explore what options are available for fertility preservation, including egg and sperm freezing, and why it's so important to initiate these discussions before starting chemotherapy or radiation. Dr. Jain also explains the difference between Letrozole and Clomid, the impact of estrogen-sensitive cancers on IVF treatments, and innovative approaches like random-start cycles and DuoStim protocols. Whether you're facing a cancer diagnosis or simply thinking proactively about your reproductive future, this conversation is filled with knowledge and reassurance. Key Takeaways: Why it's essential to discuss fertility before starting cancer treatment. The role of Letrozole in estrogen-sensitive cancers and fertility preservation. Differences between Letrozole and Clomid, and why Letrozole is often preferred. How new protocols like DuoStim and random-start cycles are improving outcomes. Why fertility preservation is important even for those without a cancer diagnosis. Guest Bio: Dr. Nirali Jain (@eggspert_md) is a board-certified OB/GYN and fertility specialist at Reproductive Medicine Associates (RMA) in Basking Ridge, New Jersey. She earned both her undergraduate degree in neurobiology (with a minor in dance!) and her medical degree from Northwestern University, before completing her residency at Weill Cornell/NYP, where she served as co-Chief Resident, and her fellowship in reproductive endocrinology and infertility at NYU Langone. Deeply passionate about women's health and fertility preservation, Dr. Jain blends the latest research and cutting-edge treatments with compassionate, patient-centered care. Her interests include third-party reproduction and oncofertility, and she is especially passionate about supporting patients navigating fertility preservation through a cancer diagnosis. Outside of the clinic, Dr. Jain is a trained dancer, a dedicated global traveler, and an adventurer working toward hiking all seven continents with her husband. Her diverse experiences, from international medical rotations to personal connections with friends and family navigating infertility, have shaped her into a warm, resourceful, and determined advocate for her patients. Links and Resources: Visit RMA websiteFollow Dr. Nirali Jain on Instagram For more information about Michelle, visit www.michelleoravitz.com To learn more about ancient wisdom and fertility, you can get Michelle's book at: https://www.michelleoravitz.com/thewayoffertility The Wholesome Fertility facebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/ Instagram: @thewholesomelotusfertility Facebook: https://www.facebook.com/thewholesomelotus/ Disclaimer: The information shared on this podcast is for educational and informational purposes only and is not intended as medical advice. Please consult with your healthcare provider before making any changes to your health or fertility care. -- Transcript: # TWF-Jain-Nirali (Video) [00:00:00] **Michelle Oravitz:** Welcome to the podcast Jain. **Dr. Nirali Jain:** Thanks so much for having me **Michelle Oravitz:** Yeah, so. **Michelle Oravitz:** I'm very excited to talk about this topic, which, um, actually you don't really hear a lot of people talking about, which is how to preserve your fertility if you're going through a cancer diagnosis and if you have to go through treatments. 'cause obviously that can impact a lot on fertility. **Michelle Oravitz:** I have, um, seen actually like a colleague of mine go through. And she also preserved her fertility and, and now she has a baby boy. so it's really nice. **Michelle Oravitz:** to **riverside_nirali_jain_raw-video-cfr_michelle_oravitz's _0181:** so nice. **Michelle Oravitz:** So I'd love for you first to introduce yourself and kind Of give us a background on how you got into this work. **Dr. Nirali Jain:** Of course. Um, so I am Dr. Narly Jane. I am, um, an OB GYN by training, and then I did an additional, after completing four years of residency in OB GYN and getting board certified in that, I did an additional training in reproductive endocrinology and [00:01:00] infertility or otherwise known as REI. So now I'm a fertility specialist. **Dr. Nirali Jain:** Um, I trained at Northwestern in Chicago, so I went to undergrad and medical school there. And then, um, home has always been New Jersey for me, so I moved back out east to New Jersey. Um, I did all my training actually in New York City at Cornell for residency and NYU for fellowship. Um, and then moved to the suburbs. **Dr. Nirali Jain:** Um, and now I'm a fertility specialist in, in Basking Ridge at Reproductive Medical Associates. **Michelle Oravitz:** Very impressive background. That's awesome. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** I'd love to hear just really. About what your process is. If a person has been diagnosed with cancer, like what is the process? What are some of the things that you address if they are trying to preserve fertility, and what are some of the concerns going **Dr. Nirali Jain:** yeah, yeah. All great questions. So, you know, there's a lot of us, uh, the Reis. Are a very small, [00:02:00] there's a very small number of us. So in terms of specializing in fertility preservation, technically we all are certified to treat patients with cancer and kind of move them through fertility preservation before starting chemotherapy. **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** Um, luckily we've been working closely with oncologists in the past several years just to establish some type of streamlined system because having a diagnosis of cancer and hearing all that information. Especially when you're young is so hard. So I think that's, that's where my interest started in terms of being able to speak to and counsel cancer patients. **Dr. Nirali Jain:** I think it is a very specific niche that you really have to be comfortable with in our field. Um, I. So I'll kind of walk you through, you know, what it, what does it look like, right? Um, you go into your oncologist's office suspecting that you have this, this lump. I'll take breast cancer, for example. It could really be any kind of cancer. **Dr. Nirali Jain:** Um, but breast cancer in a reproductive age patient or someone that's in those years where you're starting [00:03:00] to think about building a family, planning a family, um, or if you have kids at home, that's usually the type of patient that we see come in with a breast cancer diagnosis. So. Kinda just taking that, for example, um, the minute that you're diagnosed, it's really your oncologist's responsibility to counsel you on what treatment options are going to be offered to you. **Dr. Nirali Jain:** And then based off of the treatment options, it's important to know how that affects your reproduction. So how does it affect your ovaries in the short term, in the long term, um, in any way possible. So. Once a patient is initially referred from their oncologist to myself or any other fertility specialist, they come into my office and we just have a 30 minute conversation really talking about family planning goals. **Dr. Nirali Jain:** Any kids that they've had in the past either naturally conceived or through um, IVF, and then we talk about where they're at in their relationship. Are they married, are they not? Are they with a partner, [00:04:00] a male partner, a female partner, whatever it might be. It's important to know the social standpoint, um, especially in this sensitive phase of life. **Dr. Nirali Jain:** So patient patients usually spend anywhere from 30 minutes to an hour. Um, just kind of talking through where they're at, how they're feeling, what their ultimate childbearing goals are. And then from there we do an ultrasound and that's when I'm really able to see, you know, the, the reproductive status. **Dr. Nirali Jain:** So what do the ovaries look like? What does the uterus look like? Is there something that I need to be concerned about from a baseline GYN standpoint? Um, and all of those conversations are happening in real time. So. I think one of the things is patients come in and they're like, I'm already so overwhelmed with all this information from my oncologist, and now my fertility specialist is throwing all this information at me. **Dr. Nirali Jain:** Luckily, the way I like to frame it is you come in and you just let go. Like you let us do the work because in the background we're the ones talking to your oncologist. We're the [00:05:00] ones giving that feedback and creating a timeline with your oncologist. Um, and really I think just getting in the door is the hardest part. **Dr. Nirali Jain:** So once patients are here to see us, we go through the whole workup. We do anything that we would do for a normal patient that came in for fertility preservation. And then based off of where they're at in their journey, we talk about what makes sense for them, whether that means freezing embryos, freezing eggs, they're very similar in terms of the, the few weeks leading up to the egg retrievals. **Dr. Nirali Jain:** So I have that whole conversation just at the initial visit. And then from there we talk about the timeline behind the scenes and make sure that it works with their lives before moving forward. **Michelle Oravitz:** So for people listening to this, why, and this might be an obvious question, but to some it might not be, **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** why would somebody want to preserve. eggs or sperm. 'cause I've had actually some couples **Dr. Nirali Jain:** Yep. **Michelle Oravitz:** come to me where the husband preserved the sperm and they had to go through IVF just because he was going [00:06:00] through cancer treatments. So he had to preserve the sperm ahead of time. **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** people need to consider doing that before doing cancer treatments? **Dr. Nirali Jain:** So there are certain cancer treatments that do affect the ovaries and the sperm health, and you know, for men and women, it affects your reproductive organs. In a similar way, um, depending on the type of chemotherapeutic agent, there are some that are more dangerous in terms of, um, being toxic to your ovaries or toxic to your sperm. **Dr. Nirali Jain:** And those are the instances where we are really thinking about what's the long-term impact because there's medications that oncologists do give patients, and our oncologists are amazing, the ones that we work with, Memorial Sloan Kettering from Reproductive Medical Associates through RMA, um, and. **Dr. Nirali Jain:** They're just so good at what they do and are so well-trained, so they know in the back of their mind, is this going to impact your ovaries or your sperm health or not? Um, and I [00:07:00] think that any chemotherapy, you know, your ovaries are these, these small organs that are constantly turning over follicles every month. **Dr. Nirali Jain:** So every month we're losing those eggs, and if they don't become. If an egg isn't ovulated, it doesn't become a baby, it's just gonna die off. So I counsel even patients that don't have cancer, I counsel them on fertility preservation as young as possible. You know, between the ages of 28 and 35, that's like the best time to preserve your fertility. **Dr. Nirali Jain:** So in cancer patients, there's an extra level added to that where even if they are a little bit younger, a little bit older. Your eggs are not gonna be the same quality. There's gonna be higher level of chromosomal errors, more DNA breakage, um, and, and bigger issues that lead to issues with conceiving naturally afterwards. **Dr. Nirali Jain:** So I think that it's important to consider how that chemotherapy is going to affect them or how surgery would affect them if it was, for example, a GYN cancer where [00:08:00] we're removing a whole ovary, you know, what, what do we have to do to preserve your fertility in that case? And those are important conversations to have. **Michelle Oravitz:** Yeah. for sure. I know that a lot of people are also concerned, you know, with going through the IVF process, you're taking in a lot of estrogen, a lot of hormones, and many cancers are actually estrogen sensitive. So I wanted to talk to you about that. 'cause I know that the data shows that it's. It's been fine, which some people might find surprising, but I wanted you to address that and just kind of **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** from your perspective. **Dr. Nirali Jain:** That's so interesting that you asked that question because I actually, my whole I I graduated fellowship last year and my entire, like passion project in fellowship was looking at one of the drugs that we use to suppress the estrogen levels specifically in cancer patients. Um, and I had presented this at a few of our reproductive meetings. **Dr. Nirali Jain:** Um, A SRM is one of our annual meetings where all of the reiss get together. A lot of male fertility [00:09:00] specialists come and we kinda just talk about. Specific things and fertility preservation for cancer patients is, has been an ongoing topic of interest for all of us. Um, and it's important to know that there are different medications that we can offer. **Dr. Nirali Jain:** Letrozole is the one that I, um, have a particular love for and I, uh, you know, I use all the time for my patients, um, for different reasons, but it suppresses the exposure that your body has to estrogen. And there's mixed data, um, out there in terms of, you know, does Letrozole suppression actually impact, you know, does it help or. **Dr. Nirali Jain:** Or does it have no impact on your future risk of cancer after treatment? Um, and that honestly is still up for debate. But what we do know is that there's no increased risk of cancer recurrence in patients that have undergone fertility preservation with or without Letrozole. Um, Letrozole is one of those things that we can give, and the way it works is basically. **Dr. Nirali Jain:** It masks that [00:10:00] conversion. It, it doesn't allow for conversion from those androgens in the male hormones over to estrogen. Um, and so your body doesn't really see that estrogen exposure. It stays nice and low throughout your cycle, and it does help with actually ovarian maturation and getting mature eggs harvested and, um, helps a little bit with, with quality too. **Dr. Nirali Jain:** So I think that it's really nice in terms of having that available to us, but know that. It's not, it's not essential that you have it, really, the data showing plus minus. Um, but there are certain things that we can do to protect the ovaries, protect your exposure to estrogen. Um, and so that shouldn't be top of mind of concern when we're going through fertility preservation, even with an estrogen sensitive cancer. **Michelle Oravitz:** Actually, so, uh, on a different topic, kind of going back to that, so Letrozole versus Clomid, I, it's like a, the questions I personally feel just based on what I've heard and like my own research that Letrozole would be kind of like the more. [00:11:00] Um, the, it's, it's a little better, but I know that it really depends on the person as well. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** they might do better with Clom, but I'd love to hear your perspective and kind of pick your brain on this. **Dr. Nirali Jain:** totally. You're choosing all the, all the right questions because these are all of my, my specific interests and niches. So **Michelle Oravitz:** Oh, **Dr. Nirali Jain:** Letrozole is basically, you know, we use Letrozole and Clomid in. Patients that don't have cancer and patients that come in for an intrauterine insemination, that's kind of the most common scenario where we're thinking about, you know, which medication is better? **Dr. Nirali Jain:** Letrozole or Clomid and Clomid used to be the, the most common medication that we use, we dose patients, you know, have 50 milligrams of Clomid, give them five days of the medication. It's an oral pill. Feels really easy and. The way it works is really, it recruits more than one follicle, so it really helps with the release of, um, more than one follicle growing more than one follicle in the ovary. **Dr. Nirali Jain:** Um, but it has a little bit [00:12:00] higher of a risk of twins because that's exactly what it's good at. Um, Clomid, not so much in the cancer. In the cancer front, it's not really used there because it's considered, from a scientific perspective, it's considered like a selective estrogen receptor modulator. So it doesn't necessarily suppress your estrogen levels in the same way that Letrozole does versus. **Dr. Nirali Jain:** Letrozole is an aromatase inhibitor, so it really blocks the chemical conversion of one drug or one hormone to the other hormone. Um, the reason we love Letrozole so much, and I don't mean to like gush over Letrozole, but um, it's a mono follicular agent, so it works really well at recruiting one follicle **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** you know, every OB-GYN's nightmare in a way is having multiples when you didn't intend on having multiples at all. **Michelle Oravitz:** so **Dr. Nirali Jain:** Um. **Michelle Oravitz:** were saying that, um, there's more of a chance of twins, it's Clomid, not letrozole. **Dr. Nirali Jain:** Yes, there's a higher chance with Clomid versus Letrozole. And I mean, don't get me wrong, there's a chance of twins with [00:13:00] any type of assisted reproductive technology. Even when we're doing single embryo transfers, there's a chance that it's gonna split. So, um, the chance is always there just like it is in the natural world. **Dr. Nirali Jain:** But we know for a fact that. CLO is really good at recruiting many follicles. It's good for certain patients that don't respond well to Letrozole. Um, but Letrozole is kind of our, our go-to drug these days just because of all the benefits that we've seen. **Michelle Oravitz:** Awesome. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** These are all fun things to ask because I, I love talking to our eis 'cause there's so much information that I'm always **Dr. Nirali Jain:** totally. **Michelle Oravitz:** learn a lot from my patients in my own research, but it's really cool. Picking your guys' brains. So another question I have, and I have actually talked to Dr. Andrea Elli, he's been on, **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** and he does a lot of endometriosis and, and immune related work as well, **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** so. I'd love to know just from your perspective. One thing that I do know from, based on what I've heard is that the, [00:14:00] guess like you were just saying, that breast cancer or estrogen sensitive breast cancer doesn't seem to be affected by IVF cycles, however, and endometriosis lesions do get affected. **Dr. Nirali Jain:** Yeah. **Dr. Nirali Jain:** that's a great question. So, you know, every, there are so many complex G mind diagnoses that the, that our patients come in with. Um, and endometriosis is a big one because there is clear data that endometriosis is linked to infertility. So we think about, you know, when a patient comes in with endometriosis, we really do think about the different treatment options and what are the short-term and long-term impacts of the hormones that we're giving 'em. **Dr. Nirali Jain:** Um, these days, again, kind of going back to Letrozole, we, letrozole is something that I give all of my endometriosis patients because it helps suppress their estrogen because we know. **Michelle Oravitz:** interesting. **Dr. Nirali Jain:** is very responsive to estrogen and leads to this dysfunctional regulation of all the endometrial tissue that can really flare in a, [00:15:00] in a cycle, or shortly after a cycle. **Dr. Nirali Jain:** I. So we really, for endometriosis patients, the, the best treatment is being on birth control because we don't see that hormonal fluctuation. The up and down of the estrogen and the progesterone, that's what leads to those flares. Um, so I really, I watch patients closely after their cycles too, because you definitely can have an endometriosis flare and we say the best treatment for endometriosis is pregnancy, right? **Dr. Nirali Jain:** That's when you're suppressed, that's when you're at your lowest. Um, and patients, my endo patients feel so good in pregnancy because they have. Hormones that are nice in that baseline, they're not getting periods of course. Um, and that's truly, truly the best treatment. **Michelle Oravitz:** That's interesting. **Dr. Nirali Jain:** But it is important to consider when you're going through infertility treatments. **Dr. Nirali Jain:** How does my endometriosis affect the short and long-term effects of the fertility medications? And really not to, not to say that they're bad in any way. I think a lot of endometriosis patients go through IVF and have success and do really, really well, and that's kind of the push that they need. [00:16:00] Um, but it's important to be mindful of the bigger picture here. **Dr. Nirali Jain:** It's not just, you're not just a number of. A patient with endo coming in, getting the same protocol. It's really individualized to the extent of your lesions, what symptoms you're having, what grade of endometriosis, where your lesions are. So we're the RAs are thinking about everything before we actually start your protocol. **Michelle Oravitz:** It's crazy how in depth it is, and it's, it, there's just so, it's so multifaceted, **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** when it's females **Dr. Nirali Jain:** totally. **Michelle Oravitz:** are a little, I mean, they can, you know, there, there's definitely a number of things, but it's not as complicated and interconnected **Dr. Nirali Jain:** Exactly. Exactly. That's so true. **Michelle Oravitz:** And so one question I actually have, this is kind of really off topic, but something that I was curious about. **Michelle Oravitz:** 'cause I heard about a while **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** a, a type of cancer treatment that was used. I'm not sure exactly what it was, but for some reason it actually caused follicles to grow, [00:17:00] or to multiply. And they were **Dr. Nirali Jain:** Interesting. **Michelle Oravitz:** this definitely. Puts, um, the whole idea of like a woman being born with all the follicles she'll ever have on its head, I thought that was really Interesting. **Michelle Oravitz:** Now I learned a little bit about it. I don't think it really went further than that, **Dr. Nirali Jain:** Mm-hmm. **Michelle Oravitz:** one of those things that they're like, Hmm, this is interesting. I don't know, it was kind of a random side effect of this chemo drug. I dunno if it was a chemo drug or a cancer drug. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** ever heard of that. **Michelle Oravitz:** So I was just **Dr. Nirali Jain:** I haven't, I mean, that's interesting. I feel like I'd have to look into that because that would be definitely a point of interest for a lot of Reis. But it kind of does go back to the point of, you know, women are really born with all the eggs we're ever gonna have. So it's about a million, and then it just goes down from there. **Dr. Nirali Jain:** And the, by the time you start having periods, I like to kind of show my patients a chart, but you have a couple hundred thousand eggs and you ovulate one egg a month. That's, you know. Able to [00:18:00] progress into a fertilized egg and then into a, an embryo into a baby, um, if that's your goal. But otherwise, patients that are having periods and not trying to actually get pregnant, we're losing hundreds of eggs a month. **Dr. Nirali Jain:** So. **Michelle Oravitz:** Mm. **Dr. Nirali Jain:** It's important to kind of think about that decline, and it's important to know that that rate can be faster in patients with cancer, patients with low ovarian reserve. And sometimes when you have the two compounded, that's when a fertility specialist is definitely, you know, in the queue to, to have a discussion with you in terms of what that means and how you can reach your family building goals despite being faced with that, with that challenge. **Michelle Oravitz:** Yeah. **Michelle Oravitz:** I mean, 'cause we know oxidative stress is one of the things that can cause, uh, **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** quality eggs, but it's also can cause cancer. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** um, similar, you know, like things that really deplete the body could definitely impact. Um, and then what are your thoughts? I know I'm asking you all kinds of random questions, **Dr. Nirali Jain:** I love it. **Michelle Oravitz:** are your thoughts about doing low simulation in certain [00:19:00] circumstances versus high stem? **Michelle Oravitz:** Sometimes people don't respond as well to higher stems. **Dr. Nirali Jain:** Yeah, that's a great point. I think that it kind of all goes back to creating an individualized protocol. If. A patient's going to a practice and basically just getting a protocol saying, this is our standard. We start with our standard of, you know, I, I think about the standard, which is 300 of the FSH or that pen that you dial up, and then 150 units of that powder vial. **Dr. Nirali Jain:** And we have patients mixing powders all the time, and that's kind of our blanket protocol that we give patients. But that's not really what's happening behind the scenes. And if you're given a protocol that's, and being told, you know, this is kind of what we give to everyone, it's probably not the right fit for you. **Michelle Oravitz:** Yeah, I **Dr. Nirali Jain:** Um, there are certain patients that respond to a much lower dose and do really, really well, and then some patients that need a much higher dose. Um, and I think it's, that's kind of like the fun part of being an REI of being able to individualize the [00:20:00] protocol to the patient. Um, and I know for a fact there are so many, luckily, you know, we have so many leaders in REI that have been. **Dr. Nirali Jain:** Have dedicated their entire careers to researching these different protocols and how they can help different patients. Um, patients with lower a MH, you know, might benefit from a duo stim protocol, for example. That's kind of the first one that comes to mind, but a protocol where we're using those follicles from the second half of a cycle. **Dr. Nirali Jain:** I would've never thought that those were the follicles that **Michelle Oravitz:** Oh, **Dr. Nirali Jain:** would be better than the first half of the cycle, **Michelle Oravitz:** Wait, **Dr. Nirali Jain:** but, **Michelle Oravitz:** that. Explain that. Um, because I think that that's kind of a unique **Dr. Nirali Jain:** mm-hmm. **Michelle Oravitz:** that I haven't heard of. **Dr. Nirali Jain:** Yeah, so there's this new day. It's still kind of developing, but um, kind of going back to, you know, what's an individualized protocol? Duo STEM is one of the newer protocols that we've started using. I, I've used it once or twice in patients. Um, but it goes back to the research that shows that you might actually have two different periods of time in a menstrual cycle where you could potentially recruit [00:21:00] follicles. **Dr. Nirali Jain:** You could have a follicular phase where there's a certain cohort of follicles recruited, and then you have a follicle that forms creates a corpus glut. **Michelle Oravitz:** um, protocols **Dr. Nirali Jain:** Yep. And then you basically go through the follicular protocol and then a few days after a retrieval, instead of waiting for a new follicular cohort or follicular recruitment from the first half of your menstrual cycle, you actually use the luteal phase and you recruit those follicles that would've actually died off or have been prematurely recruited in a prior cycle. **Dr. Nirali Jain:** So **Michelle Oravitz:** that's So **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** you just do a similar, I guess, um, medicine, **Dr. Nirali Jain:** go right back into it. **Michelle Oravitz:** do the same exact thing, but right after ovulation. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** Fascinating. That's really interesting. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** has been your experience with that? **Dr. Nirali Jain:** I think it's, honestly, it's mixed. Um, so far, you know, our data from fertility and sterility and A SRM, it, it shows support for these DUO STEM [00:22:00] protocols, saying that if patients don't have that great quality of eggs or if they have a very low number, maybe they'd benefit from starting the meds earlier and recruiting follicles. **Dr. Nirali Jain:** A little bit earlier. Um, so we've seen positive results so far. A lot of work to be done in terms of really understanding it. Um, and of course, as a new attending, I have a lot more experience to kind of build on. Um, but I, I have seen success from it. **Michelle Oravitz:** That's fascinating. Are there any other new technologies, like new add-ons, um, that you've seen, that you've found to be really cool or interesting? **Dr. Nirali Jain:** I think the biggest thing, actually, kind of going back to our whole topic for today is fertility preservation cancer patients. One of the biggest things that I've learned recently is that we used to start fertility, um, patients. You know, only in the beginning of the cycle days, two or three is technically like when most. **Dr. Nirali Jain:** Most clinics, um, start patients, but for our cancer patients, sometimes you don't have that time. You don't wanna wait a full month to [00:23:00] restart, um, your, you know, your menstrual cycle and then do the fertility preservation and then delay chemotherapy a full month. So we started doing what we call random starts. **Dr. Nirali Jain:** So you basically start a patient whenever they come in. You know, it could be the day after your consultation, the day of your consultation. I've kind of seen all of the above. Um, and we've seen really good success with random starts, per se. Um, and we've been doing a lot more of that, where it's not as dependent on where you're at in your cycle. **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** Um, obviously there's a difference in outcomes. You might not be a great candidate for it, so definitely it's worth talking to your doctor about it. But it kind of gives relief to our cancer patients where if you have a new cancer diagnosis and you're like, oh, I just finished my period, like, I can't even start a cycle until next month. **Dr. Nirali Jain:** That's not always true. Um, so it's always worth it to go into see a fertility specialist and just get, you know, get the data that you need right away, and then you can make a decision later on. **Michelle Oravitz:** For sure. Um, Yeah. **Michelle Oravitz:** and I wanted to kind of cover a lot of different topics 'cause I know that [00:24:00] some people are gonna wanna hear what you have to say that don't necessarily, or, uh, have cancer. But it is important. I, I think that, you know, if you get to thirties and you haven't gotten married or you don't have a partner, I think it's really important to preserve your fertility in general. **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** important thing. And then if you were going through a cancer diagnosis and you decided to preserve your fertility, um, guess more for women because they're eventually going to be thinking about transfers after they go through treatment. So what are some of the things that they would need to consider as far as that goes? **Michelle Oravitz:** Like after the **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** then they go through the cancer treatments. Um, and then what, how long should they **Dr. Nirali Jain:** yeah. Like what does it look like? So I've had patients that come back, you know, in my fellowship training I did a, a couple research projects on patients that came back to pursue an embryo transfer, um, after chemotherapy agent. And basically compared them to how they did, um, [00:25:00] compared to patients that didn't have cancer and just froze their embryos or froze their eggs and then came back to pursue a transfer and. **Dr. Nirali Jain:** I think the, the most reassuring thing from the preliminary data that we have is saying that there's no difference in pregnancy rates and no difference in life birth, **Michelle Oravitz:** Awesome. **Dr. Nirali Jain:** of whether they had chemotherapy or not. After freezing those eggs and going through fertility preservation. **Michelle Oravitz:** Amazing. **Dr. Nirali Jain:** Um, in terms of where your body needs to be, I think the oncologist, we, we wait for their green light. **Dr. Nirali Jain:** We wait for their signal to say, you know, she's safe to carry a pregnancy. **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** And then once we do that, we basically treat you like any other patient. So if you're coming in for a cycle, if you're having periods, then it's reasonable to try a natural cycle protocol, wait for your body to naturally ovulate an egg. **Dr. Nirali Jain:** And instead of obviously hoping that egg will fertilize, we, um, use a corpus luteum. We use the progesterone from the corpus luteum to really support this embryo being implanted into the uterus. Um. Yeah. [00:26:00] And then there's also another side. I mean, some patients don't get their periods back and they always ask like, what if I never get my period back? **Dr. Nirali Jain:** What if I'm just like in menopause because of the chemotherapy agents? And for that, we can start you on a synthetic protocol or basically an estrogen dependent protocol where you take an estrogen pill for a certain number of days. We monitor your lining, then we start progesterone, um, to support your hormones from that perspective instead of relying on your ovaries to release the progesterone that they need, um, and then doing the embryo transfer a few, few days after progesterone starts. **Dr. Nirali Jain:** So there's definitely different protocols depending on where your menstrual health is at after the chemotherapy or after the cancer treatment. Um, but it's important to kind of just know that. That there's options. It doesn't mean that it's the end of the road if you all of a sudden stop getting your period. **Michelle Oravitz:** Yeah, for sure. I mean, 'cause you, technically speaking, you can really control a lot of that. More so for transfers **Dr. Nirali Jain:** Yep. **Michelle Oravitz:** Retrievals really is kind of like what [00:27:00] eggs you have, what the quality is. But people can be in complete menopause and you guys can still control their cycles for transfer, which is kind of. A huge difference **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** in the **Dr. Nirali Jain:** exactly. That's exactly right. Yeah. **Michelle Oravitz:** interesting. Any other, um, new, new things that you're, you guys are excited about? I always like to hear about like the new and upcoming things **Dr. Nirali Jain:** Of course. **Michelle Oravitz:** actually before, which I thought was fascinating. Yeah. **Dr. Nirali Jain:** I feel like there's always like updates and, and new data and things like that coming out, but just know, I think it's important for patients to know, like we're constantly, we're, the reason I chose to even pursue this field was because it's new. Right. There's something that we are discovering every day, every year, and that's what makes our, our conferences so important to attend, um, to really just stay up to date. **Dr. Nirali Jain:** Um, but we are, uh, constantly updating our embryology standards, the way we thaw our eggs, and the success rate associated with a thaw and [00:28:00] how we treat our embryos and the media that we use, right? Like, so we're really thinking about the basic science perspective every single day, and that's what makes this field so unique. **Michelle Oravitz:** It is really awesome. And so do you guys specialize specifically on, um. Egg freezing and, and I mean specific fertility preservation in patients that do that have cancer that are going through treatments, do you guys specialize specifically in that? I mean, I know you do range **Dr. Nirali Jain:** Yeah. Yeah, because it's such a small community, we all have our own niches and we all kind of have our own interests and **Michelle Oravitz:** Yeah. **Dr. Nirali Jain:** no like specific training. There are a couple courses that you take that I took in in training as well, just to kind of understand what it sounds like to, I. Council of fertility preservation, patient with and without cancer. **Dr. Nirali Jain:** Um, and then, you know, you kind of just learn by experience and you form a niche for something that you're passionate about. 'cause that's what makes you, you know, really thorough in, in your treatment. [00:29:00] So that's one of my interests. Um, and, but I would say, **Michelle Oravitz:** training for that. It's just like **Dr. Nirali Jain:** yeah, **Michelle Oravitz:** just know how to treat that in **Dr. Nirali Jain:** exactly. **Michelle Oravitz:** especially if you're interested in doing that. **Dr. Nirali Jain:** Exactly. That's exactly right. It's kind of, it just comes with the experience comes with your mentors and who you're surrounded by, and everyone kind of helps each other get to that point. But there are several specialists in our practice at RMA that specialize specifically in fertility preservation in cancer patients. **Dr. Nirali Jain:** So we have a close communication with our oncologist and they know who to refer to within the practice because everyone has their own little interests. **Michelle Oravitz:** Amazing. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** Um, definitely. I, like I said, I really enjoy picking your brain because it's a lot of fun for me. I, I do **Dr. Nirali Jain:** Totally. **Michelle Oravitz:** acupuncture, so **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** and I, I think that it's just so crazy that our fields don't work together. I mean, we kind of do, but I think, I just feel like it would be so great **Dr. Nirali Jain:** exactly.[00:30:00] **Michelle Oravitz:** the expertise because you guys have immense. Benefits like in, in, uh, technology and incredible innovations and, and then the natural aspect of really understanding the, the body. And I, I just think that it would work so amazing together if it was more of like a thing. 'cause it, I know in China they actually combine the two **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** eastern. **Dr. Nirali Jain:** Yeah, I mean I think that that's so important and there is data that shows, you know, there's actually a recent study that came out just a few weeks ago on the benefits of acupuncture for fertility patients. And we know that, I mean, I recommend it to all of my patients, specifically the day of the embryo transfer. **Dr. Nirali Jain:** We, luckily, we offer it on site at RMA and we have acupuncturists that come in and, and do a session before and after the embryo transfer, and I think. A lot of that is targeted towards stress relief. But I also think that holistically it's important to feel at your best when we're doing something that's so crucial to your, to your health. **Dr. Nirali Jain:** So to really focus on the diet, focus on stress relief, [00:31:00] focus on meditation, yoga, whatever it takes to get to your best wellbeing when you're going through fertility treatments, um, is so important. So I appreciate **Michelle Oravitz:** Mm-hmm. **Dr. Nirali Jain:** like you that really specialize in the other side of. Of this, because I do consider it still part of the holistic medicine that we need to really maximize success for our patients. **Michelle Oravitz:** Awesome. Well, **Dr. Nirali Jain:** Yeah, **Michelle Oravitz:** Jane, this is such a pleasure Of talking to you. You've given us some, so much great information and we've definitely dived into a, do a topic that I don't typically, I haven't yet spoken about. But, um, that being said, it's such an important topic to talk about. And thank you so much for coming on today. **Michelle Oravitz:** Oh, **Dr. Nirali Jain:** course. **Michelle Oravitz:** I get off, how can people find you? **Dr. Nirali Jain:** That's a great question. So I have, um, a social media page. I, it's called Expert nc. So like EGG, **Michelle Oravitz:** I **Dr. Nirali Jain:** um, expert nc. Try, tried to make it a little bit humorous. Um, but I'm all over social [00:32:00] media and would love to hear from anyone that is listening. I, you know, every, every day I get different, um, dms and I'm happy to respond. **Dr. Nirali Jain:** I love hearing about everyone else's. Stories and things like that. Um, so that is kind of my main, main social media platform. Um, and then through like RMA and Reproductive Medical Associates, we also have a YouTube channel. We have an Instagram page, um, of our office available, um, as well that is public. **Dr. Nirali Jain:** So you can find us pretty easily if you just kind of hit Google. But um, yeah, I'm kind of developing my social media platform as the expert and I hope it grows. **Michelle Oravitz:** Love it. Great. **Dr. Nirali Jain:** Yeah. **Michelle Oravitz:** was such a pleasure talking to you. Thank you. so much **Dr. Nirali Jain:** Thank you. **Michelle Oravitz:** today. **Dr. Nirali Jain:** Of course. Thank you so much for having me. [00:33:00]
This week hosts Tiffany Cross, Angela Rye, and Andrew Gillum speak with the Mayor of Newark, Ras Baraka. The Mayor made headlines last Friday after he was arrested by ICE while protesting a new ICE detention facility in his home city. Mayor Baraka’s arrest comes in the context of Trump’s sprawling campaign of retribution against his “political enemies.” From law firms, to judges, to universities and elected officials–Trump is weaponizing the federal government against anyone he perceives to have wronged him. The legal attacks are often effective even if his administration doesn’t win the case… Today our hosts discuss government retaliation. The chilling effect of these attacks could have long term impacts on free speech, the application of justice, and our ability to govern. Mayor of Newark, New Jersey, Ras J. Baraka is a Newark native, poet, and educator. Under his leadership, Newark achieved a 60-year low in crime, replaced 23,000 lead service lines, and reduced homelessness by 57%. A member of Alpha Phi Alpha, Ras is a lifelong advocate for equity and opportunity. He’s now running a campaign for Governor of New Jersey. If you’d like to submit a question, check out our tutorial video: http://www.instagram.com/reel/C5j_oBXLIg0/ and send to @nativelandpod. We are 537 days away from the midterm elections. Welcome home y’all! —--------- We want to hear from you! Send us a video @nativelandpod and we may feature you on the podcast. Instagram X/Twitter Facebook NativeLandPod.com Watch full episodes of Native Land Pod here on YouTube. Native Land Pod is brought to you by Reasoned Choice Media. Thank you to the Native Land Pod team: Angela Rye as host, executive producer and cofounder of Reasoned Choice Media; Tiffany Cross as host and producer, Andrew Gillum as host and producer, and Lauren Hansen as executive producer; Loren Mychael is our research producer, and Nikolas Harter is our editor and producer. Special thanks to Chris Morrow and Lenard McKelvey, co-founders of Reasoned Choice Media. Theme music created by Daniel Laurent.See omnystudio.com/listener for privacy information.
11:16 - Guest: Kent Lee Platte, creator of the groundbreaking Relative Athletic Score (RAS) metric for NFL Draft prospects, on the Commanders for each of their two NFL Drafts with Adam Peters as general manager being No. 1 in the NFL in average RAS for players taken in the draft, whether prioritizing players who test very well athletically is a wise NFL Draft strategy, why offensive tackle Josh Conerly Jr. most stands out regarding players selected by the Commanders in the 2025 NFL Draft in terms of RAS, perspective on receiver Jaylin Lane and running back Jacory Croskey-Merritt in terms of RAS, when an NFL player's athletic prime truly is and much more 32:45 - Capitals: preview of the Caps' best-of-seven series against the Carolina Hurricanes in the second round of the Stanley Cup Playoffs 44:40 - Nationals: discussion of the Nats winning two out of three games at the Cincinnati Reds 56:40 - Orioles: breakdown of the O's losing two out of three games against the Kansas City Royals Download the PrizePicks app and use the promo code "Galdi" for $50 instantly after you play your first $5 lineup The Nace Law Group, Accident & Injury Lawyers - 202-902-7611 and make sure that you mention that Al Galdi sent you Call Nova Fireplace And Stove at 571-513-3803, mention that Al Galdi sent you and receive $50 off any fireplace service before Sept. 1, 2025 - this includes cleaning, safety inspection, tune-up and diagnostic work For advertising inquiries, email Sales@BlueWirePods.com Please note that time stamps may be slightly off depending on rotating national ads