Podcasts about Type 2 diabetes

Food as Medicine: Why Medical Nutrition Therapy and Medically Tailored Meals Belong in Modern Healthcare: Registered dietitian nutritionist Leyla Muedin argues that food should be treated with the same rigor as medication through medical nutrition therapy (MNT) and “diet prescriptions,” integrating nutrition into treatment plans rather than leaving it as optional advice. She cites evidence that medically tailored meals (MTMs) can improve outcomes and reduce costs, including a Health Affairs simulation estimating $23.7B in first-year net savings nationwide and a Nature Medicine analysis of a Massachusetts Medicaid demonstration (2020–2023) showing MTM recipients had 31% fewer hospitalizations, 20% fewer emergency visits, and $3,433 lower total healthcare costs, offsetting 98% of program costs. She discusses food insecurity, expanding Medicaid coverage via Section 1115 waivers, EHR integration, and how MTMs support adherence for conditions such as diabetes, cardiovascular disease, chronic kidney disease, depression, and IBS (including low FODMAP).

Hot flashes, blood sugar swings, brain fog... is it menopause, diabetes, or both?In this episode of the TCOYD Podcast, Dr. Steve Edelman is joined by renowned menopause expert Dr. Cindy Stuenkel, endocrinologist and Professor Emerita at UC San Diego, for an insightful conversation about how menopause affects women living with diabetes. Together, they explain why menopause is much more than a normal stage of aging. It's a major metabolic transition that can influence blood sugar management, insulin resistance, heart health, sleep, mood, and overall quality of life. The conversation explores what actually happens during perimenopause, menopause, and postmenopause, why hormonal fluctuations can make glucose management more challenging, and how continuous glucose monitoring can help distinguish hot flashes from hypoglycemia. Dr. Edelman and Dr. Stuenkel also discuss the latest evidence on hormone replacement therapy, newer non-hormonal treatment options, the importance of protecting heart health, and practical strategies to help women navigate this stage of life with greater confidence. Whether you're living with type 1 or type 2 diabetes, approaching menopause, currently experiencing it, or supporting someone who is, this episode provides practical guidance and evidence-based information to help you feel more prepared. Key TopicsWhat is perimenopause, menopause, and postmenopause?How hormonal changes affect blood sugar and insulin resistanceWhy menopause can increase glucose variability in women with diabetesThe difference between hot flashes and hypoglycemiaHow continuous glucose monitoring can help during menopauseMetabolic changes that occur during the menopause transitionWhy cardiovascular risk increases after menopauseThe connection between menopause, weight gain, and abdominal fatGLP-1 medications and menopauseThe latest recommendations on hormone replacement therapyNew non-hormonal treatments for hot flashesSleep, mood, brain fog, and quality of life during menopauseHeart health strategies for women living with diabetesHow partners can better support someone going through menopauseTrusted menopause resources and when to seek medical care Subscribe for practical diabetes management tips, expert conversations, and the latest advances in diabetes care to help people living with diabetes live healthier, more confident lives. ★ Support this podcast ★

Insulin-resistant patients with type 2 diabetes who require high-dose therapy have long lacked a rapid-acting option concentrated enough for compact insulin pumps. New pharmacokinetic data on an ultra-rapid U-500 insulin aspart, alongside additional phase 3 results for a combined once-weekly insulin icodec-semaglutide regimen, both aim to close persistent gaps in insulin delivery for this population. In this episode of Diabetes Dialogue, hosts Diana Isaacs, PharmD, and Natalie Bellini, DNP, reviewed two studies addressing unmet needs in insulin therapy for type 2 diabetes.The investigational agent AT278 is a highly concentrated insulin aspart formulated at 500 units/mL, distinct from existing U-500 regular human insulin, which behaves more like an intermediate-acting product. In a single-center, randomized, double-blind, crossover euglycemic clamp study spanning body mass index from 25 to 38 kg/m², AT278 produced significantly faster absorption and a greater glucose-lowering effect within the first hour versus both standard U-100 insulin aspart and U-500 regular human insulin. The ultra-rapid pharmacokinetic and pharmacodynamic profile held consistent across the BMI range studied.Current U-500 regular insulin requires dosing 30 minutes before meals while simultaneously serving as basal and prandial coverage, complicating use in automated insulin delivery systems and limiting compatibility with smaller-volume pumps. A concentrated, rapid-onset formulation could allow patients with high insulin requirements to use compact pumps and extended-wear infusion sets without the absorption problems tied to large-volume subcutaneous depots. Drawn from an early-phase study, the findings position AT278 as a potential first ultra-rapid option for prandial dosing in this population, though regulatory approval for pump use remains undefined.Separately, the phase 3 COMBINE 4 trial evaluated a fixed combination of once-weekly insulin icodec (Awiqli) and semaglutide, known as IcoSema, against once-daily insulin glargine U-100 in 485 adults with type 2 diabetes and baseline A1C above 8%. Over 40 weeks, IcoSema reduced A1C by 3.32 percentage points versus 2.44 points with glargine, a between-group difference of 0.88 percentage points, while producing a 0.79 kg weight reduction compared with a 3.81 kg gain with glargine. Time in range reached 79.8% with IcoSema versus 64.5% with glargine, consistent with the mechanistic rationale of pairing glucagon-like peptide-1 receptor agonism with basal insulin to limit postprandial excursions.These results build on earlier COMBINE 1 through 3 data, which showed IcoSema achieving noninferior or superior A1C reduction, superior weight outcomes, and lower hypoglycemia rates versus comparators. A single weekly injection combining basal insulin with a GLP-1 receptor agonist could reduce treatment burden and consolidate pharmacy copays, though semaglutide exposure remains capped by concurrent insulin titration, averaging 0.66 mg in COMBINE 4. Whether either agent reaches United States practice, including reported uncertainty around a domestic IcoSema launch, will determine their eventual role in managing insulin-resistant type 2 diabetes.

Cardiologist and electrophysiologist Dr. Gregory Marcus, chair of the American Heart Association scientific statement writing group, reveals evidence on coffee/caffeine and cardiovascular health. He discusses how earlier assumptions that caffeine triggers arrhythmias are complicated by genetics, individual risk factors, and mostly observational research. Marcus reviews randomized and observational findings: the CRAVE trial showed no increase in premature atrial contractions but more premature ventricular contractions on coffee days; a trial in post-cardioversion patients found less atrial fibrillation with daily coffee. Observational data suggest lower risks of type 2 diabetes, heart attack, stroke, and AFib among coffee drinkers, while heart failure risk may be lower at low intake but higher around 4–5 drinks/day. He cautions against extrapolating benefits to energy drinks, discusses additives like sugar, touches on alcohol, cannabis, Mediterranean/DASH diets, pollution, and evolving AFib treatments, wearables, and pacing/ablation technologies.

Low-fat dairy shown to confer no weight, cholesterol benefits over full-fat dairy; FDA and USDA to define ultra-processed foods for first time—but what are they really? Newly discovered tick-borne Bourbon virus can be fatal—but is it more pervasive than we think? Thorne supplement maker—sold 3 years ago for $700 million—acquired by Procter & Gamble for $3.8 billion. Those dark skin blotches—are they melasma, or just age spots? Is low-mercury salmon a hype? That fishy smell—does it mean your seafood is spoiled?

California Almond Board-funded research finds potential benefits for adults with prediabetes

Episode#342-Taped July 15, 2026 We talk about taking a lifestyle change approach in preventing, treating and even reversing Type 2 diabetes. According to the NIH Type 2 diabetes remission is achievable through intensive lifestyle interventions focused on weight management, nutrition, physical activity and behavior modification. Joining us is Chris Reade, an entrepreneur, technologist and Founder of LookFar and Carrollton Entreprise Services. He's sharing with us his personal health joourney that inspired him to write his book, “Beating Diabetes: How a botched insurance renewal saved my life.” Chris Reade's story is powerful because he showed us how that if you plan and do the proven strategies to treating Type 2 diabetes with lifestyle habits and practices you can actually reverse insulin resistance and gain control and improve your blood sugar levels and just most importantly live a healthier life. Buy Chris Reade's book Beating Diabetes: How a botched insurance renewal saved my life. Find out more about Chris Reade on his website.. www.beatingdiabetes.us It's All About Health & Fitness-Vicki Doe Fitness podcast Ranked on the Top 25 Midwest Fitness Podcasts to Listen to… with additional national recognition on the Top 100 US fitness podcast. Rate This Podcast Give us a 5-star review.  We appreciate you! Take this quick audience survey. Thank you! FREE Metabolic Makeover Masterclass Webinar Replay! Learn how to reset your metabolism, boost energy, and support sustainable weight loss using simple, science-backed strategies. Enroll in the Vicki Doe Fitness Academy to get instant access to the replay and begin your healthy living journey today. Vicki Doe Fitness-STORE Discover the Vicki Doe Fitness-STORE—your destination for stylish apparel, fitness gear, and wellness essentials like yoga mats, water bottles, candles, and premium supplements. Shop now and elevate your health journey! Resources *Note: Some of the resources below may be affiliate links, meaning Vicki Doe Fitness receives a commission (at no extra cost to you) if you use the link to make a purchase. Thank you for your support! Herbs and spices are the keys to delicious, flavorful, and sophisticated meals! FREE DOWNLOAD- Herbs and Spices Cheatsheet Let's get ECO-friendly.  Try ECOLunchbox.com ECOlunchbox specializes in stainless steel bento boxes, artisan fair trade lunch bags, napkins, snack sacks, and other eco-friendly lunchware. They are a certified green business.  ECOlunchbox is a consumer products company started by an eco mom in the San Francisco Bay Area. ECOLunchbox.com Go to our Resources page-   For the most recommended tools, you need to succeed on your healthy living journey!! Listen and share our podcast show- “It's All About Health & Fitness-” Vicki Doe Fitness Subscribe to Apple Podcast Subscribe on Stitcher Or on any of the platforms that you listen to your podcast! Watch & Subscribe on YouTube! Catch our latest health & wellness videos on YouTube at Vicki Haywood Doe – Vicki Doe Fitness YouTube-Vicki Haywood Doe-Vicki Doe Fitness Want a text from us? Join us to receive a health wellness message!

Once-weekly basal insulin therapy has moved from clinical trial data to pharmacy shelves, offering clinicians a new option for patients who struggle with the daily burden of insulin injections. The shift addresses a persistent adherence problem in basal insulin therapy, where missed or inconsistent daily dosing undermines glycemic control.In this episode of Diabetes Dialogue, hosts Diana Isaacs, PharmD, and Natalie Bellini, DNP, discuss the pharmacy launch of insulin icodec (Awiqli), the first once-weekly basal insulin now available in the United States.The approval rests on data from approximately 4200 participants across the phase 2 and phase 3 ONWARDS program. In insulin-naive participants enrolled in ONWARDS 1, 3, and 5, insulin icodec produced superior reductions in hemoglobin A1c compared with once-daily basal insulin. Among participants switching from daily basal therapy in ONWARDS 2, icodec showed noninferior glycemic control alongside improved treatment satisfaction scores.Insulin icodec has also been studied in type 1 diabetes but did not receive approval in this population after trials showed higher rates of hypoglycemia relative to daily basal insulin. Additional studies in type 1 diabetes are ongoing, leaving open the possibility of future expansion beyond the current type 2 indication.Dosing requires new clinical habits, since insulin icodec is formulated as U-700, a concentration allowing a full week's dose to be delivered in a comfortable injection volume. Adjustments occur in 10-unit increments rather than the single-unit changes used with daily basal insulins, though the weekly total still translates into modest day-to-day changes of roughly one to two units. Patients switching from daily basal insulin require a loading dose, calculated by multiplying the total daily dose by 10.5, to reach steady state faster than a standard weekly conversion would allow.Titration follows fasting glucose. Clinicians add 20 units when readings exceed 130 mg/dL, maintain the dose between 80 and 130 mg/dL, and subtract 20 units below 80 mg/dL. Because increases and decreases are dosed in 20-unit blocks, most cycles are reassessed over two to four weeks rather than week to week.The reduced injection frequency carries particular relevance for older adults, caregivers, and patients whose adherence to daily regimens has proven inconsistent. As pharmacy access expands, coverage and prior authorization requirements will shape how quickly insulin icodec moves into routine practice, but early trial and satisfaction data point toward a meaningful shift in basal insulin management.

Sarah Aitken is a nurse practitioner, metabolic health practitioner, and the founder of Diabetes Game Changer. Her work is deeply personal: after struggling with obesity, prediabetes, and early type 2 diabetes herself, Sarah discovered the power of nutrition and lifestyle change and transformed her own health, losing nearly 100 pounds along the way. Today, she combines her clinical experience with what she learned through her own journey to help people understand insulin resistance, improve their metabolic health, and take control of type 2 diabetes through sustainable, evidence-based lifestyle changes. In this episode, Dr. Brian, Dr. Tro and Sarah talk about… (00:00) Intro (02:49) Type 2 diabetes and body types (06:01) The woeful lack of education in medical schools on nutrition (10:32) How Sarah first educated herself on the physiology of insulin resistance and nutrition (20:42) The power of community and accountability (25:37) Providing a healthy alternative to the mega health care system that profits off of patients' illness (30:46) Food labels and grocery shopping (39:00) Fiber (43:43) Food, exercise, and blood sugar spikes (48:17) Food addiction and support (51:48) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Sarah Aitken: Reversible (book): https://www.amazon.com/dp/B0GX2WJNVK Diabetes Game Changer: https://www.diabetesgamechanger.com/ FB: https://www.facebook.com/diabetesgamechanger Dr. Brian Lenzkes:  Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian:  Website: https://toward.health Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together.  Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more.  Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888  Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://toward.health/community/

Have you or someone you know been diagnosed with type 2 diabetes, only to discover later it was actually type 1? You're not alone.In this episode of the TCOYD Podcast, Dr. Steve Edelman is joined by Dr. Schaefer Boeder, endocrinologist, Medical Director of Paradigm Research, Associate Professor at UCSD, for an eye-opening discussion about LADA (Latent Autoimmune Diabetes in Adults)—one of the most commonly misdiagnosed conditions in diabetes. Together, they explain why so many adults are initially misdiagnosed with type 2 diabetes despite the warning signs that should raise suspicion for LADA, and why getting the correct diagnosis can dramatically change treatment and long-term outcomes.The conversation explores how LADA differs from both classic type 1 and type 2 diabetes, why the autoimmune process develops more slowly, and when antibody testing should be considered. Dr. Edelman and Dr. Boeder also discuss the importance of preserving beta cell function, the role of continuous glucose monitoring, advances in disease-modifying therapies, and why there has never been a more exciting time for research in adults who developed type 1 diabetes later in life. Whether you've been diagnosed with LADA, care for someone who has, or simply want to better understand adult-onset autoimmune diabetes, this episode provides practical guidance and hope for more accurate diagnoses in the future.Key Topics:What is LADA (Latent Autoimmune Diabetes in Adults)?Why LADA is so often mistaken for type 2 diabetesCommon signs that may point to a misdiagnosisHow LADA differs from classic type 1 and type 2 diabetesWhy many adults don't fit the "typical" diabetes profileAutoantibody testing and when it should be consideredThe role of GAD antibodies and C-peptide testingWhy preserving beta cell function mattersPreventing diabetic ketoacidosis (DKA) through earlier diagnosisHow continuous glucose monitoring can ease the transition to insulinCurrent treatment approaches for adults with LADAThe latest research on disease-modifying therapies and preserving insulin productionScreening resources, clinical trials, and where the future of LADA research is headed✨ Subscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram:   / tcoydFacebook:   / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

With Bahira Shahim, Ayah Fayad and Kari Feldt, Karolinska Institute, Stockholm - Sweden Link to European Heart Journal paper Link to European Heart Journal editorial

Lowering A1C in Prediabetes and Using Less Insulin on a Low-Carb Diet: Leyla Muedin, a registered dietitian nutritionist, answers listener questions about blood sugar and insulin. Responding to Rita, whose hemoglobin A1C rose from 5.6 to 5.8, Layla says “glucose hacks” to blunt carb absorption aren't appropriate at that level and recommends a strict very low-carb/keto approach (under 25 grams of total carbs per day), avoiding sugar, starchy vegetables, fruit (except avocado), sweetened beverages, and even alternative sweeteners and low-carb processed products; she suggests retesting A1C after three months and avoiding testing during illness or inflammation. She also addresses Joy, a type 1 diabetic, affirming low-carb eating to reduce insulin needs and weight gain, criticizing an insurance pricing structure that charges more when insulin is used more slowly, and expressing concern about doctors prescribing insulin too quickly for type 2 diabetes instead of dietary intervention.

Could you please comment on the new study that finds protein restriction could slow aging?Considerations for protein intake across the lifespanMy bone mineral density has improved with strontium. Should I stop taking it?  What about vitamin K2?

David Seymour says a decision to broaden diabetes medication met his expectations. Pharmac's widening access for several medicines for type two diabetes from September, helping to lower blood sugar and reduce kidney complications. The Associate Health Minister says more than 30 thousand people will benefit by removing ethnicity from the question. Seymour told Mike Hosking he wrote a letter to the board of what he expected. He says they need to be the best organisation in the world and forget embedding the Treaty. LISTEN ABOVE See omnystudio.com/listener for privacy information.

In this episode of the Pain and Performance Podcast, Dr. Derrick Hines sits down with Dr. Jason Shumard to explore the root causes of insulin resistance, type 2 diabetes, and chronic inflammation.They discuss why blood sugar is only part of the story, the role of toxins, cellular health, and advanced testing, and how a functional medicine approach can help uncover what's driving metabolic disease. The conversation also covers GLP-1 medications, detoxification, regenerative therapies, and practical strategies for improving long-term metabolic health.In This Episode-- Why insulin resistance is more than a blood sugar problem-- The connection between inflammation and chronic disease-- Advanced testing beyond routine lab work-- How toxins impact metabolic and cellular health-- The role of detoxification in improving health-- Where GLP-1 medications fit into treatment-- Lifestyle strategies for preventing and reversing metabolic dysfunction#BloodSugar#InsulinResistance#Type2Diabetes#FunctionalMedicine#MetabolicHealthDERRICKInstagram:https://www.instagram.com/derrickbhines/Youtube:https://www.youtube.com/@DrDerrickJASONWebsite: https://drshumard.comYouTube: https://www.youtube.com/@drjasonshumardInstagram: https://www.instagram.com/drjasonshumarddc/LinkedIn: https://www.linkedin.com/in/jason-shumard-853658140/Facebook: https://www.facebook.com/drjasonshumard 

In this episode, Dr. Steve Edelman and Dr. Jeremy Pettus are joined by Dr. Shara Bialo, Senior Medical Director of Type 1 Diabetes Immunology at Sanofi, pediatric endocrinologist, and person living with type 1 diabetes, for an in-depth discussion about what happens before type 1 diabetes is diagnosed. Together, they explore the autoimmune process that begins months or even years before symptoms appear, why early detection matters, and how screening is changing the future of type 1 diabetes care. Dr. Bialo shares her personal diagnosis story, discusses common misconceptions about what causes type 1 diabetes, and explains the three stages of the disease. The conversation also covers who should be screened, how diabetes autoantibody testing works, the benefits of preserving beta cell function, and why identifying people before they develop symptoms can lead to better long-term outcomes and fewer cases of diabetic ketoacidosis (DKA). Whether you have type 1 diabetes, have a family member at risk, or simply want to better understand the latest advances in prevention and early detection, this episode provides valuable insights into one of the fastest-moving areas of diabetes research.Key Topics:Dr. Shara Bialo's personal journey living with type 1 diabetesWhy type 1 diabetes is an autoimmune disease, not simply a blood sugar problemThe role of genetics, viral infections, and the immune systemUnderstanding the three stages of type 1 diabetesWhy most people diagnosed with type 1 diabetes have no family historyAdult-onset type 1 diabetes and why it is often mistaken for type 2 diabetesWhat diabetes autoantibodies are and how screening worksWho should consider screening for type 1 diabetesAvailable screening options, including blood tests and home screening kitsThe emotional challenges families face when considering screeningThe importance of preventing diabetic ketoacidosis through early detectionWhy preserving beta cell function can improve long-term outcomesItaly's national screening program and the future of population-wide screeningResources available through screenfortype1.comThis content was produced with support from Sanofi and screenfortype1.com.✨ Subscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram:   / tcoydFacebook:   / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

Is your child eating more than you did at their age? Why is India seeing childhood obesity, insulin resistance, and Type 2 diabetes at younger ages than ever before?In this episode of the Kidsstoppress Parenting Podcast, Mansi Zaveri – Founder of Kidsstoppress, India's leading parenting platform and Certified Conscious Parenting Coach – speaks with Dr. Malhar Ganla, one of India's leading experts in paediatric obesity and metabolic health.Together, they unpack why Indian children are becoming overweight earlier, how family habits shape lifelong health, the truth about insulin resistance, childhood obesity, processed foods, screen time, emotional eating, and what parents can do to build healthier lifestyles without fear or guilt.If you're looking for the best parenting podcast in India, evidence-based parenting advice, or practical conversations on raising healthy children, this episode is for you.Support the show

What Triggers Age-Related Belly Fat? New Stem Cell Findings and a Nutrition Perspective: Nutritionist Leyla Muedin discusses research from City of Hope (published in Science) on why belly fat increases with age even without major weight gain, emphasizing the health risks of visceral fat as an endocrine organ linked to inflammation, diabetes, heart disease, and accelerated aging. The study suggests aging activates adipocyte progenitor cells (APCs) and produces an age-specific stem cell population called committed preadipocytes (CP-As) that generate new fat cells, with experiments showing older APCs create more fat cells even when transplanted into young mice. Single-cell RNA sequencing identified greater CP-A activity in middle-aged mice and similar cells in higher numbers in middle-aged human tissue. Researchers implicate the LIFR signaling pathway and propose future therapies to block these cells, while Leyla questions root causes and argues metabolic dysfunction—insulin resistance, hyperinsulinemia, high carbohydrate intake, and sedentary behavior—should be addressed nutritionally rather than via a pill.

Type 2 diabetes has become one of the most common chronic diseases in the world, but research continues to show that lifestyle can play a powerful role in preventing and even reversing the disease.In this solo episode of the NHA Today Podcast, Dr. Stephan Esser explores the science behind insulin resistance and shares five evidence-based lifestyle strategies that have been shown to dramatically reduce diabetes risk and improve blood sugar control. You'll learn why excess body fat, inflammation, nutrition and physical activity all play critical roles in metabolic health, and how small daily changes can lead to meaningful long-term results.Resources

BUFFALO, NY — July 23, 2026 — A new #research paper was #published in Volume 18 of Aging on July 8, 2026, titled “TM4SF1 is a surface marker of senescent pancreatic β-cells.” The study was led by first author Ana Beathriz Leite Lorente from Joslin Diabetes Center and Harvard Medical School, and São Paulo State University (UNESP), Brazil, and corresponding author Cristina Aguayo-Mazzucato from Joslin Diabetes Center and Harvard Medical School. Type 2 diabetes is characterized by insulin resistance and the progressive loss of pancreatic β-cell function. With aging and metabolic stress, senescent β-cells accumulate within the pancreas, producing less insulin while releasing inflammatory signals that contribute to disease progression. Although eliminating these dysfunctional cells has emerged as a promising therapeutic strategy, a major challenge has been identifying markers that distinguish senescent β-cells from healthy cells with sufficient precision. This study identifies transmembrane 4 L six family member 1 (TM4SF1) as a highly selective surface marker of senescent β-cells, providing a promising candidate for the future development of more selective therapies for type 2 diabetes. In this study, the researchers searched for cell-surface proteins that specifically identify senescent β-cells. Using RNA sequencing, flow cytometry, immunofluorescence, and analyses of both mouse and human pancreatic tissue, they compared TM4SF1 with the previously established senescence marker urokinase-type plasminogen activator receptor (uPAR/PLAUR). Their findings showed that TM4SF1 is expressed predominantly in senescent β-cells while exhibiting much lower expression in non-senescent β-cells and other tissues, making it a more β-cell-specific surface marker than uPAR. Full press release - https://www.aging-us.com/news-room/new-surface-marker-could-advance-precision-therapies-for-type-2-diabetes DOI - https://doi.org/10.18632/aging.206398 Corresponding author - Cristina Aguayo-Mazzucato - Cristina.aguayo-mazzucato@joslin.harvard.edu Abstract video - https://www.youtube.com/watch?v=tNbFKdleTJo Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206398 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, senescent β-cell, type 2 diabetes, transmembrane 4 l six family member 1, urokinase-type plasminogen activator receptor To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

I am a Type 2 Diabetic. I was diagnosed in December 2022.Since being diagnosed I have made a lot of life style changes with the goal of being off my diabetes medication.In November 2023 I achieved that goal. In April 2025 my doctor recommended I stopped using a Continuous Blood Glucose Monitor - CGM to monitor my blood glucose levels.Learning how to eat whole foods, and reduce sugary foods and highly processed foods has been key to my success in Reversing my Type 2 Diabetes.Here I am offering a suggestion for breakfast to help with metabolism of Fat Soluable vitamins

Type 2 diabetes may be the diagnosis—but what if it is also a symptom of deeper problems affecting the body?In this episode of The Dr. Haley Show, Dr. Michael Haley speaks with Dr. Jade Guerra about the functional medicine approach to Type 2 diabetes, insulin resistance, hypothyroidism, Hashimoto's disease, autoimmune conditions, environmental toxins, nutrition, sleep, and chronic illness.Dr. Guerra is both a Doctor of Chiropractic and a Family Nurse Practitioner with nearly 35 years of experience. Instead of applying the same treatment plan to every patient, she investigates the individual metabolic, hormonal, digestive, environmental, and lifestyle factors that may be interfering with that person's health.She explains why a diagnosis often develops years—or even decades—before it is discovered and why simply controlling a laboratory number may not address the underlying cause.DR. JADE GUERRA'S RESOURCESWebsite and Free Masterclasses:https://jadeguerra.com/The End of Type 2 Diabetes NOW! Facebook Group:https://www.facebook.com/groups/321420510744852/Unbroken: Women Overcoming Low Thyroid Symptoms:https://www.facebook.com/groups/743871260049166/Instagram:https://www.instagram.com/drjadeguerra/YouTube:https://www.youtube.com/@drjadeguerraTikTok:https://www.tiktok.com/@drjadeguerraX:https://x.com/jadeguerrarealCOMPLETE EPISODE PAGEFind the video, resources, key takeaways, timestamps, and full transcript at:https://drhaley.com/type-2-diabetes-root-causes-jade-guerra/IN THIS EPISODEDr. Guerra and Dr. Haley discuss:• Why Type 2 diabetes may be a symptom of deeper metabolic dysfunction• The difference between managing symptoms and investigating root causes• Why Type 2 diabetes may sometimes be placed into remission through appropriate nutrition, lifestyle changes, and professional care• How insulin resistance and blood sugar problems can develop years before diagnosis• Why environmental toxins may contribute to inflammation, hormonal disruption, autoimmune disease, and poor metabolic health• The relationship between hypothyroidism and Hashimoto's autoimmune thyroid disease• Why testing only thyroid-stimulating hormone, or TSH, may provide an incomplete picture• How the thyroid depends upon the liver, digestive system, brain, adrenal glands, and overall metabolic health• Testing for mold, metals, pesticides, and other environmental toxins• Why aggressive detoxification programs can create problems when the body's elimination pathways are not working properly• How functional blood chemistry may be used to create an individualized health plan• Why the same diet, supplements, or treatment strategy will not work for everyone• The importance of protein, vegetables, healthy fats, hydration, electrolytes, movement, and sleep• Practical ways to make better food choices before hunger takes control• The limitations of short medical appointments and insurance-directed healthcare• The difference between a laboratory value being “normal” and being optimal• How thoughts, words, meditation, gratitude, and mindset may influence behavior and long-term healthABOUT DR. JADE GUERRADr. Jade Guerra, FNP, APRN, DC, DABCO, has nearly 35 years of experience helping people improve their health through natural and integrative approaches.She is both a Doctor of Chiropractic and a Family Nurse Practitioner, with advanced education in functional medicine, blood chemistry, brain neurotransmitters, and thyroid health.Her work focuses on identifying factors that may contribute to Type 2 diabetes, hypothyroidism, Hashimoto's disease, autoimmune conditions, and other chronic health problems. She helps patients explore appropriate changes involving nutrition, targeted supplementation, lifestyle, laboratory testing, and their environment.EPISODE TIMESTAMPS00:00 A patient is told she is no longer diabetic00:23 Welcome to The Dr. Haley Show00:51 Introducing Dr. Jade Guerra02:10 Free diabetes and thyroid masterclasses03:53 Can Type 2 diabetes be reversed?05:27 The functional medicine pioneers who influenced Dr. Guerra06:36 Taking responsibility for your own health10:35 Functional medicine versus mainstream medicine13:37 Symptom relief, medications, and health messaging17:23 Finding root causes before symptoms develop18:14 Environmental chemicals and chronic illness21:12 Thyroid disease, Hashimoto's, and childhood diabetes23:18 The markers in a complete thyroid evaluation25:19 Connections between the thyroid, gut, liver, and brain26:06 Testing for mold, metals, and environmental toxins27:26 Supporting the body's detoxification pathways29:49 The risks of unsupervised cleanses31:14 Personalized testing, nutrition, and supplements33:37 How Dr. Guerra discovered functional medicine36:35 Protein, meal planning, hydration, and sleep38:40 Sleep temperature, grounding, and electrolytes42:22 Better restaurant choices and emergency snacks45:31 Dr. Guerra's diabetes and thyroid support communities47:39 Short appointments and insurance limitations50:21 “Normal” versus optimal laboratory ranges51:22 The power of words, mindset, and meditation58:09 Where to connect with Dr. Guerra58:54 Closing thoughtsJULY 2026 LISTENER SPECIALListeners can receive $20 off a purchase of $200 or more at Haley Nutrition through July 31, 2026. The coupon code is announced during the podcast.Shop at:https://haleynutrition.com/CONNECT WITH DR. MICHAEL HALEYThe Dr. Haley Show: https://drhaley.com/Haley Nutrition: https://haleynutrition.com/YouTube: https://www.youtube.com/user/aloe1aloeveragelInstagram: https://www.instagram.com/drhaleynutrition/Facebook: https://www.facebook.com/haleynutrition/X: https://x.com/aloe1LinkedIn: https://www.linkedin.com/company/haley-nutrition/MEDICAL DISCLAIMERThis podcast is provided for educational and informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease and should not replace personal medical advice from a qualified healthcare professional.Individual health circumstances and outcomes vary. Do not discontinue, reduce, or change prescription medication without first consulting the licensed healthcare professional responsible for your care.ABOUT THE DR. HALEY SHOWThe Dr. Haley Show explores natural health, functional medicine, nutrition, personal transformation, and unconventional ideas that challenge listeners to think differently about their health.Subscribe through your favorite podcast platform so you do not miss future conversations.

Your body cannot release stored fat or heal itself when it perceives threat; gratitude is the measurable physiological switch that lowers cortisol, raises oxytocin, and allows metabolic transformation.DESCRIPTIONBen Azadi lost 80 pounds and reversed suicidal depression through metabolic healing. His father wasn't as fortunate—a preventable decline into type 2 diabetes, neuropathy, and stroke in 2014. That loss forged his purpose: reach one billion people and reverse type 2 diabetes in a million within a decade.But Azadi's message diverges sharply from the biohacking mainstream. While cold plunges and red light have their place, they're secondary. The foundation is unglamorous: gratitude, sunlight, grounding—all free, all measurable in blood work and heart rate variability.The science is stark: stress elevates cortisol; cortisol packs visceral fat around your organs. Gratitude does the inverse. Peer-reviewed research shows intentional gratitude practices reduce all-cause mortality by 9 percent and cardiovascular death by 15 percent.KetoFlex Revised, his new book, merges this psychological work with metabolic flexibility—teaching your body to burn fat instead of remaining locked into sugar dependence. His thesis: most people major in the minors, chasing complexity while overlooking what actually works.Ben Azadi Contact Info:https://KetoFlexBook.comSocial Media LinksInstagram: instagram.com/thebenazadiFacebook: facebook.com/thebenazadiYouTube: https://www.youtube.com/@KetoKampTikTok: https://www.tiktok.com/@thebenazadiSend Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com WEBSITE: Stay Off My Kitchen Table Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Ready to take control of your health?  Grab Dr. Ovadia's brand new book Stay Off My Kitchen Table now! This isn't just another diet book; it reveals why it's not just what you eat, but what your body actually absorbs that determines your health.If you're struggling with low energy, stubborn weight, or feeling like “healthy eating” isn't working… this book shows you exactly how to fix it.Learn how to reset your gutEliminate hidden foods sabotaging your progressUnlock real energy, metabolism, and longevityDon't wait until it's too late. Take action today. Get your copy of Stay Off My Kitchen Table now.Learn More:Take Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart HealthTheme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey (c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.

Grazia Aleppo, MD, discusses the evolving role of continuous glucose monitoring (CGM) in non-insulin-treated Type 2 diabetes, drawing from her recent review published in Diabetes Technology and Therapeutics that examines evolving evidence and real world implications.Practical considerations for integrating CGM into routine care are also reviewed, with an emphasis on early intervention and data-driven decision-making.Key Topics• Evidence supporting CGM use in non-insulin-treated type 2 diabetes • Limitations of A1C and the role of time in range • Impact of CGM on patient engagement and self-management • Clinical and real-world outcomes associated with CGM adoption • Practical applications for endocrinology and primary careLearn more about Northwestern Medicine Endocrinology 

Scientific Sense ® by Gill Eapen: Prof Mike Snyder leads the center for genomics at Stanford. He collects and analyzes deep data from wearables to transform helathcare through analysis and behavior modifications.Please subscribe to this channel:https://www.youtube.com/c/ScientificSense?sub_confirmation=1

In this episode of the TCOYD Podcast, Dr. Steve Edelman is joined by Raquel Baron, founder of Type One Together, to discuss the challenges, triumphs, and everyday realities of raising a child with type 1 diabetes. Diagnosed herself at age five, Raquel combines her lived experience with years of supporting families through Type One Together, an organization that provides trusted resources, educational programs, and a nationwide network of trained babysitters for children with type 1 diabetes. Together, Dr. Edelman and Raquel explore the emotional side of diabetes that often goes beyond blood sugars. They discuss helping children navigate school, sports, friendships, burnout, and growing independence, while giving parents practical strategies to reduce fear, build confidence, and create a healthier relationship with diabetes. The conversation also covers diabetes technology, social media, Afrezza for children, community support, and why perfection should never be the goal.Whether you're the parent of a newly diagnosed child or have been managing type 1 diabetes for years, this episode offers practical advice, reassurance, and reminders that children with diabetes can live full, active lives.✨ Subscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram:   / tcoydFacebook:   / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

Send us Fan MailWondering if reversing type 2 diabetes is actually possible? It is, and it doesn't have to be complicated.In this episode, you'll learn:What "reversing" type 2 diabetes really means, and why doctors call it remissionWhy losing just 5 to 7 percent of your body weight can significantly improve insulin sensitivityThe cycle of quick fixes and burnout that keeps so many people stuckOscar's personal Day One story, from hospital diagnosis to lasting lifestyle changeThe 7 simple, practical steps you can start using today to lower your blood sugar and feel greatSupport the showDownload FREE resources to help you stay focused and consistent at BeatingDiabetesLifestyle.com_____________________Connect With MeTo submit a question or join my mailing list, use the information below to connect with me.Join My Facebook Group - https://www.facebook.com/groups/beatingdiabeteslifestyle Web - www.beatingdiabeteslifestyle.comEmail - hello@beatingdiabeteslifestyle.comInstagram - @beatingdiabeteslifestyle_____________________©Oscar Camejo - The Beating Diabetes Lifestyle

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/KPS865. CME/AAPA credit will be available until June 25, 2027.Bridging Knowledge to Action: Translating Evidence Into Practice for Type 2 Diabetes Management In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/KPS865. CME/AAPA credit will be available until June 25, 2027.Bridging Knowledge to Action: Translating Evidence Into Practice for Type 2 Diabetes Management In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/KPS865. CME/AAPA credit will be available until June 25, 2027.Bridging Knowledge to Action: Translating Evidence Into Practice for Type 2 Diabetes Management In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/KPS865. CME/AAPA credit will be available until June 25, 2027.Bridging Knowledge to Action: Translating Evidence Into Practice for Type 2 Diabetes Management In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/KPS865. CME/AAPA credit will be available until June 25, 2027.Bridging Knowledge to Action: Translating Evidence Into Practice for Type 2 Diabetes Management In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/KPS865. CME/AAPA credit will be available until June 25, 2027.Bridging Knowledge to Action: Translating Evidence Into Practice for Type 2 Diabetes Management In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

GLP-1 receptor agonists have become some of the most talked-about medications in recent years. You may have heard names such as liraglutide, semaglutide (Ozempic and Wegovy), and tirzepatide (Mounjaro). These treatments have attracted attention because they can significantly reduce appetite and support weight loss while also helping to manage blood glucose levels. The breakthrough came when researchers developed long-acting versions of hormones naturally released by the body after eating, including GLP-1 and, in some cases, GIP. These hormones help regulate hunger and promote feelings of fullness. While the body's natural response lasts only a short time, modern medications extend these effects for up to a week with a single injection. Since results from major clinical trials emerged in the early 2020s, GLP-1 therapies have transformed obesity treatment, delivering weight-loss outcomes that surpass those achieved by previous medications and offering new hope for people struggling with weight management. - Laureate Professor Clare Collins, internationally distinguished leader in nutrition and dietetics, University of NewcastleSee omnystudio.com/listener for privacy information.

Attend a Live Q&A with Dr. Glandt. Reigster here.What if the way we treat type 2 diabetes is fundamentally backwards?Dr. Mariela Glandt is an endocrinologist and obesity medicine specialist who spent 15 years practicing conventional medicine before concluding, in her words, that how we treat diabetes “is actually upside down.” As co-founder of OwnaHealth, she focuses on addressing the insulin resistance underlying type 2 diabetes, not only the elevated blood sugar it eventually causes.In this episode, she walks through the science of that shift: why fasting insulin may reveal metabolic dysfunction before A1C becomes abnormal, why a laboratory “normal” range running up to 20 can be misleading, and why she believes repeatedly escalating insulin can contribute to weight gain, reduced insulin responsiveness, and worsening metabolic health.She also shares what she has learned bringing low-carbohydrate and ketogenic therapy to underserved communities in the South Bronx, where patients may be navigating severe diabetes alongside financial pressure, cultural food traditions, psychiatric illness, chronic stress, and conflicting medical advice. Her work shows that these therapies can succeed even in communities facing significant barriers to care.Dr. Glandt also breaks down what GLP-1 medications actually do, where they can help, and what they may leave unresolved—including the risks of muscle loss, inadequate protein intake, and relying on medication without addressing the patient's broader metabolic health.Questions Answered in This Episode:• What key mindset shifts do conventionally trained physicians need to make when transitioning to a more integrated approach to medicine?• How does reframing diabetes as insulin resistance change the way a doctor practices?• What are the earliest signs of metabolic dysfunction that many clinicians miss?• Can ketogenic metabolic therapy succeed in underserved communities?• What do GLP-1 medications actually solve, and what do they leave untouched?• Where can ketogenic therapy and GLP-1 medications work together?• What has Dr. Glandt observed in patients living with both metabolic and psychiatric illness?• Where does endocrinology most need to change course?Viewers will come away with a different lens on metabolic disease, one that looks beyond glucose and weight to the biological, social, and practical factors shaping a patient's health.More links:For Richer, for Poorer: Low-Carb Diets Work for All IncomesOwnaHealth: Reverse the course of chronic disease — for everyone.Special thanks to the sponsors of this episode:✅ Toups and Co – Get 15% off your first order with code METABOLIC here.✅ iRestore – Get a huge discount on the Elite and the Illumina bundle with the code LINK here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: InstagramFacebookYouTubeLinkedInPlease keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode of the TCOYD Podcast, Dr. Steve Edelman is joined by pediatric endocrinologist Dr. Anna Cymbaluk, along with Philip and his father Jim, to discuss the recent FDA approval of Afrezza inhaled insulin for children and adolescents living with type 1 diabetes. Dr. Cymbaluk served as an investigator on the INHALE-1 trial, while Philip participated in the study himself, providing a unique real-world perspective on what it is like to transition from injections to inhaled insulin, and Philip's dad, Jim provided the parent perspective as well as addressed parental concerns that might have arisen.The conversation focuses on the INHALE-1 study and the unmet challenges that continue to exist around mealtime insulin dosing in pediatric diabetes care. Dr. Cymbaluk reviews the trial design, glucose outcomes, safety data, patient satisfaction findings, and the practical realities of introducing inhaled insulin into everyday diabetes management. Philip and Jim share how Afrezza impacted school, sports, social situations, and the day-to-day burden of diabetes, particularly around pre-bolusing, corrections, and avoiding multiple injections throughout the day.Dr. Edelman and Dr. Cymbaluk also explore how Afrezza is dosed, how inhaled insulin differs from injected insulin, who may be a good candidate, and where it may fit alongside pumps and automated insulin delivery (AID) systems. For families looking for more flexibility, fewer mealtime barriers, and another option in the diabetes toolbox, this episode provides an honest look at the benefits, limitations, and real-world experience of inhaled insulin in children and teens.Key Topics• The FDA approval of Afrezza for children and adolescents living with type 1 diabetes• The design and results of the INHALE-1 pediatric clinical trial• Patient satisfaction and quality-of-life outcomes from the study• The challenges of pre-bolusing and mealtime insulin management in children and teens• How inhaled insulin compares to traditional mealtime injections• Dosing strategies, cartridge sizes, and insulin conversion considerations• Using Afrezza for corrections, meals, and post-meal dosing• The role of continuous glucose monitoring (CGM) when using inhaled insulin• Safety findings, lung-function monitoring, and cough management• Who may be a good candidate for Afrezza—and who may not be• Benefits for active children, athletes, and those participating in sports• Social situations, injection avoidance, and reducing the burden of diabetes management• Using Afrezza alongside insulin pumps and automated insulin delivery (AID) systems• The importance of having more treatment options to individualize diabetes careSupported by an unrestricted educational grant from MannKind CorporationSubscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram: / tcoydFacebook: / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

In this podcast, Jennifer Green, MD, and Jay H. Shubrook, DO, FAAFP, FACOFP, share strategies for integrating incretin-based therapies in type 2 diabetes (T2D) management in the primary care setting, including: Importance of moving beyond a glucose-centric approach to T2D care  Current evidence for incretin-based therapies in T2D Rationale for integrating these therapies into the primary care setting Shared decision-making strategies to discuss optimal T2D treatment options with patients Timing for endocrinology referral Presenters: Jennifer Green, MD Professor of Medicine Division of Endocrinology Duke Clinical Research Institute Duke University School of Medicine Durham, North Carolina Jay H. Shubrook, DO, FAAFP, FACOFP Professor, Diabetologist Department of Clinical Sciences and Community Medicine Touro University California, College of Osteopathic Medicine Vallejo, California Full program link: https://bit.ly/4uSKCqv Get access to all of our new podcasts by subscribing to the Decera Clinical Education Multispecialty Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/GUX865. CME/AAPA credit will be available until June 8, 2027.Betting on Basal Insulin: Case Studies in Improving the Odds for People With Type 2 Diabetes In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/GUX865. CME/AAPA credit will be available until June 8, 2027.Betting on Basal Insulin: Case Studies in Improving the Odds for People With Type 2 Diabetes In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

I find it shocking that, as easy as type 2 diabetes is to reverse,  backed up by even human clinical trials validating this concept, few doctors inform their diabetic patients of this. Oddly, now that GLP-1 agonist (disastrous) drugs are available, the reduction in blood sugar coupled with weight loss has brought the idea of type 2 diabetes remission to the forefront, since it now is profitable to reverse it. But you do NOT need any pharmaceutical to reverse type 2 diabetes in the majority. Support the showYouTube channel: https://www.youtube.com/@WilliamDavisMDBlog: WilliamDavisMD.comMembership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.comBooks:Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose WeightWheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed

Professor Donal O'Shea, specialist in obesity, responds to the National Centre for Pharmacoeconomics comments that Mounjaro could be deemed cost effective.

Is type 2 diabetes an incurable, progressive disease, as many doctors claim? The research says no. There is a simple, food-based approach that has been quietly studied since the 1970s, and it has helped people get their A1C back to normal without Metformin, without insulin, and without giving up a social life. In this episode, Chris Reade, entrepreneur and author of Beating Diabetes, shares his own story: his A1C jumped from normal to 9.1 in a single year, his doctor handed him a prescription and told him diabetes was an incurable, progressive disease. He walked out of that office and decided to find another way. Four months later, his A1C was back in the normal range. No Metformin. No insulin. No extreme diet. Listen now and start taking control of your blood sugar today! For show notes, visit https://fivejourneys.com/podcasts/soluble-fiber-may-be-your-best-tool-to-reverse-type-2-diabetes/  Follow us on Instagram at https://www.instagram.com/feelfreakingamazing/  Related Episodes Reverse Pre-Diabetes with a Fasting-Mimicking Diet, with Dr. Joseph Antoun How to Stop Taking Metformin, Insulin, and Ozempic for Good, with Dr. Jeffrey Hockings Lose Weight By Improving Your Leptin Sensitivity, with Dr. Bindiya Gandhi Lower Your Risk for Cancer & Chronic Diseases, with Dr. Greg Eckel Reverse Chronic Diseases using Allulose, with Neil Gyte Overcome 14 Chronic Illnesses, with Ashok Gupta Lose Weight By Getting Healthy, with Ben Azadi Try Keto for Optimal Health, with Robert & Crystal Sikes Leverage Ketosis and Fasting to Reverse Disease, with Ben Azadi Unlocking Longevity: Transform Your Health with a Fasting Mimicking Diet, with Dr. Joseph Antoun Why 16 Hours Isn't Enough for True Fasting Benefits, with Dr. Chris Rhodes Why Eating While Fasting Could Give You Better Results, with Renee Fitton

If you've ever thought, “I know what to do, so why can't I do it,” this conversation hits the nerve and gives you a way out. We sit down with Dr. John Oberg, a human behavior strategist and healthcare innovator whose work targets one of the biggest problems in modern health: chronic metabolic disease and type 2 diabetes. Along the way, John shares a near-death car crash story that reshaped how he sees faith, relationships, and service, and why that personal turning point connects directly to how people change when the stakes are real.We get concrete about what actually moves the needle: how hemoglobin A1C works, why tiny sustainable swaps can drive major blood sugar improvement, and why most “go hard on Monday” plans collapse under stress. John breaks down his core framework: focus on what you control (your thoughts and your actions), build small habits you can repeat, and create the right support system so your environment stops fighting you. We also talk GLP-1 medications, insulin, and modern telemedicine, not as magic fixes, but as tools that can help patients stabilize, lower treatment burden, and eventually reduce dependence on medication with food-as-medicine strategies.You'll also hear practical guidance you can use today: “move right” by shifting from processed food toward whole food, “move more” with 10-minute blocks of intentional walking, and stop grazing all day so your body gets clear fed and fasting periods. We even share a blunt, compassionate patient story framed as Door A, Door B, or Door C that shows what non-judgmental care really looks like when someone feels stuck.If this helped you, subscribe, share it with a friend who needs hope, and leave a review so more people can find these conversations. What's one small change you're willing to start this week?Join the What if it Did Work movement on FacebookGet the Book!www.omarmedrano.comwww.calendly.com/omarmedrano/15min

In this episode of the TCOYD Podcast, Dr. Edelman and Dr. Pettus are joined by pediatric endocrinologist Dr. Jamie Wood, medical director of pediatric diabetes at Rainbow Babies & Children's Hospital and an investigator on the INHALE-1 trial, to talk through inhaled insulin in kids and where it fits in real-world pediatric care.The conversation focuses on the recent approval of Afrezza for children as young as six, and what the INHALE-1 trial actually showed. Dr. Wood walks through the study design, A1C results, lung-function and safety data, and the practical aspects of dosing inhaled insulin in a pediatric population. Rather than positioning it as a replacement for injections or pumps, the discussion centers on finding the right fit for each child's needs, from the newly diagnosed kid with a needle phobia to the teen trying to dose discreetly during a 20-minute school lunch.Dr. E, Dr. P, and Dr. Wood also discuss the everyday realities that shape how this option is used, including the set-dose cartridge sizes, a titration approach refined in clinic, and how families are mixing and matching tools alongside automated insulin delivery. The takeaway is encouraging: there are more options than ever for managing mealtime insulin in kids, and this one may help fill some of the gaps left by injections and pumps.Key Topics • The recent approval of inhaled insulin for children as young as six • How the INHALE-1 pediatric trial was designed • A1C results and what the primary endpoint analysis showed • Continuous glucose monitor (CGM) metrics across the two groups • Lung-function (FEV1) monitoring and pediatric safety • Weight and body mass index (BMI) findings • Why mealtime dosing is a leading unmet need in pediatric type 1 diabetes (T1D) • The set-dose cartridge approach and how it reframes meal sizes • A real-world titration method for inhaled insulin • Managing cough and other practical considerations • Needle phobia and the kids who struggle most with injections • Using inhaled insulin alongside automated insulin delivery (AID) systems • What's coming next, including a smaller cartridge dose and a new-onset trial Subscribe for practical diabetes management tips, technology updates, and treatment breakthroughs that help people with diabetes live healthier, more flexible lives.More diabetes resources:Website: tcoyd.orgBlog: tcoyd.org/blogPodcast: tcoydthepodcast.transistor.fmInstagram: / tcoydFacebook: / tcoydStay connected! Sign up for our monthly newsletter here!Support TCOYD's educational programs: tcoyd.org/donate ★ Support this podcast ★

Perimenopause, Insulin Resistance, and Persistent Muscle & Joint Pain: A Functional Medicine Framework: Nutritionist Leyla Muedin discusses perimenopausal musculoskeletal symptoms—new or persistent joint pain, muscle aches, and tendon problems—and highlights a Clinician's Journal article by physical therapist Tara Moore proposing insulin resistance screening in perimenopausal musculoskeletal care. She explains that declining estradiol during the menopausal transition can worsen insulin signaling, increase visceral fat, and reduce insulin sensitivity, affecting skeletal muscle recovery and potentially contributing to tendinopathies and poor or short-lived responses to localized treatments like PT. The framework emphasizes assessing systemic metabolic contributors (e.g., sedentary behavior, high-carbohydrate nutrition patterns, PCOS, central weight gain, stress, sleep disruption) and addressing mediators such as inflammation and impaired glucose utilization. She suggests integrating metabolic risk assessment, sleep and stress strategies, resistance training, and interdisciplinary referrals, arguing that nutrition and supplementation—especially a low-carb approach—may improve recovery and pain outcomes.

Is there a diet that can help reverse type 2 diabetes? Discover how to reverse diabetes naturally with a diet that improves blood sugar control, eliminates cravings, and reduces insulin resistance.0:00 The diet that reverses diabetes naturally0:23 Can you reverse diabetes?1:38 Insulin resistance and prediabetes 5:09 High blood sugar explained 6:08 Side effects of type 2 diabetes 6:47 How to reverse diabetes naturally 8:49 A low-carb diet and intermittent fasting 9:30 Signs of blood sugar problems10:13 The best diabetes diet plan12:15 Foods to avoid if you have type 2 diabetes12:58 Natural blood sugar control

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3424: Jacquelyn Cafasso shares practical snack ideas that make it easier to manage type 2 diabetes without spending time on complicated meal prep. From protein-rich nuts and Greek yogurt to fiber-packed vegetables, avocados, and popcorn, these simple options can help support steady blood sugar levels while keeping hunger under control throughout a busy day. Read along with the original article(s) here: https://www.healthline.com/health/type-2-diabetes/grab-and-go-snacks Quotes to ponder: "Studies show that having at least five servings per week of nuts is significantly associated with a lower risk of cardiovascular disease." "Air-popped popcorn is a great snack option for people with type 2 diabetes." "When you have type 2 diabetes, you can snack smart by aiming for items high in protein and fiber, but low in sodium and sugar." Episode references: U.S. Department of Agriculture (USDA): https://www.usda.gov American Diabetes Association: https://diabetes.org Learn more about your ad choices. Visit megaphone.fm/adchoices

The “Enhanced Games”, with no-holds-barred performance-enhancing drugs, yields scant advantages over “clean” contests; Does saturated fat increase insulin resistance? Can a heart attack victim avoid statin use with CoQ10? Omega-3 fish oil shows promise vs. type 2 diabetes; Motorized e-scooter use needs to be regulated NOW!

Sami Inkinen (@samiinkinen) is a Finnish-born, Stanford-trained entrepreneur and the founder and CEO/president of Trulia and Virta Health. Virta is on a mission to reverse metabolic disease in one billion people using technology, AI, and nutrition. A world-class endurance athlete, Sami is a triathlon age-group world champion and an 8-hour, 24-minute Ironman finisher, having completed the Hawaii Ironman World Championship seven times.This episode is brought to you by:Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/TimAG1 all-in-one nutritional supplement: DrinkAG1.com/TimWealthfront high-yield cash account: Wealthfront.com/Tim Wealthfront disclaimer: New clients get 3.30% base APY from program banks + additional 0.75% boost for 3 months on your uninvested cash (max $150k balance). Terms and conditions apply. The Cash Account offered by Wealthfront Brokerage LLC (“WFB”) member FINRA/SIPC, not a bank. The base APY as of 1/30/26 is representative, can change, and requires no minimum. Tim Ferriss, a non-client, receives compensation from WFB for advertising and holds a non-controlling equity interest in the corporate parent of WFB, which creates a conflict of interest. Individual experiences and outcomes will differ. Instant withdrawals may be limited by your receiving firm and other factors. Investment advisory services provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, not bank-guaranteed or FDIC-insured, and may lose value.DISCLAIMER:The content of this episode is for informational purposes only. Neither Sami Inkinen nor Tim Ferriss is a medical professional, and nothing discussed here should be taken as medical advice or a substitute for consultation with a qualified healthcare provider.Timestamps:[00:00] Start.[01:45] How Sami uses 15 minutes every Sunday to outrun the universe.[03:37] Virta: at a thousand employees and counting.[04:15] The 5 a.m. boot-up: cold lake, core work, and emptying the dishwasher.[06:45] Why mood follows movement before the brain even boots up.[11:54] Saying no to 99% of what “normal people” do.[19:29] The weekly architecture.[20:29] Two direct reports: the case for radical subtraction.[21:09] 553 CEO letters and the case for one scalable habit.[32:36] The text-file life plan.[33:32] The 15-year personal plan Sami stumbled into by accident.[34:30] The four-pillar formula for not cracking in 26 years of founder life.[38:20] What “white Japanese people” and beer steins in saunas have in common.[45:55] Smoke saunas, löyly, and the one Finnish word worth knowing.[48:37] The lean, ten-percent-body-fat triathlete who was quietly going prediabetic.[53:07] Why 93% of American adults are metabolically unhealthy.[56:05] Reversing type 2 diabetes the way Virta actually does it.[1:00:17] Most surprising interventions.[1:03:32] The pancreatic cancer trial that bought patients 35% more time.[1:07:02] The McDonald's protocol: how to reverse diabetes from the drive-thru.[1:16:00] Why GLP-1 adherence collapses and Virta's doesn't.[1:21:10] Vegans, tofu, and the hardest macronutrient to get right.[1:25:27] The dose-response curve that lets perfect stop being the enemy of progress.[1:29:32] VO2 max blocks: how Sami trains an 80+ engine without burning out.[1:41:56] Hacking 10% off your running speed in four weeks.[1:46:09] Progressive overload, specificity, and the case against the long ride.[1:50:07] 45 days, three hours, and a contract to keep a marriage afloat.[1:55:27] The lightning strike in the middle of the Pacific that started a family.[2:01:15] The 36-year-old who bought his first car only because his wife made him.[2:05:40] The book recommendation no one saw coming: Trejo.[2:07:51] The PSA: chronic, progressive, and irreversible — three words Sami refuses.[2:11:40] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.