Podcasts about fobt

Visit NascentMC.com for medical writing assistance. Visit learnAMAstyle.com for information on AI in Medical Writing and Editing - **mRNA Anti-EBV Cancer Vaccine**: The novel mRNA therapeutic cancer vaccine WGc-043 has been approved for clinical trials by the FDA, targeting Epstein-Barr virus (EBV) related cancers such as nasopharyngeal carcinoma and natural killer T-cell lymphoma. It stimulates the immune system to respond against EBV and associated malignancies, showing superior efficacy and safety in preliminary trials. A phase 1 clinical trial is currently focusing on patients who have failed second-line therapies, aiming to determine the optimal dose and evaluate safety and efficacy metrics. - **BTX-9341 for Breast Cancer**: The FDA has approved the investigational new drug application for BTX-9341, a novel cyclin-dependent kinase (CDK) 4/6 bifunctional degrader, intended for hormone receptor-positive, HER2-negative breast cancer resistant to existing CDK4/6 inhibitors. This drug targets and degrades CDK4/6 proteins, crucial for cancer cell cycle regulation, aiming to overcome resistance to current treatments. A phase 1 trial will assess its safety, biological activity, and efficacy both as monotherapy and combined with fulvestrant. - **Nivolumab Hyaluronidase Formulation**: The FDA has accepted a Biologics License Application for a subcutaneous formulation of nivolumab co-formulated with recombinant human hyaluronidase, enhancing convenience by reducing administration time compared to the intravenous version. This application includes all previously approved solid tumor indications for nivolumab, with a PDUFA date set for February 28, 2025. The subcutaneous version aims to provide faster and easier administration, supported by data from the Phase 3 CheckMate-67T study. - **ColoSense Colorectal Cancer Screening Test**: The FDA has approved ColoSense, a noninvasive colorectal cancer screening test using multi-target stool RNA for adults aged 45 and older at average risk. ColoSense, distinct from traditional FOBT tests, uses RNA biomarkers to detect CRC with high sensitivity and has shown promising results in clinical trials, detecting 93% of CRC cases and 45% of advanced adenomas in average-risk individuals. This new test offers a significant improvement in sensitivity and specificity over existing methods. For the complete shownotes visit nascentmc.com/podcast

Today we welcome Thomas Dambo to the podcast. Thomas is a Recycling sculpture Artist and activist hailing from Denmark.  He recent built a giant troll on beautiful Bainbridge Island.   We talk on sight, as the last parts of the project get finished.   Special thanks to: Scan Design Foundation (SDF), serving as overall project lead and visionary, the Paul G. Allen Family Foundation serving as a fiscal patron, the Bainbridge Island Metro Parks and Rec District (BIMPRD) serving as a site partner, and Friends of the BainbridgeTroll (FOBT) serving as Project Manager. FOBT worked to secure local fiscal sponsorship through Arts and Humanities Bainbridge (AHB). Park Commissioner Janow served as lead between SDF and FOBT. Bainbridge is but one of six partner sites in the overall project - and while we are super excited to host/highlight our troll, it is in concert with the overall NW Way of the Bird King project and our site partners (Portland, Vashon, West Seattle, Issaquah, & Seattle). The B.I.STANDER Podcast is a conversational podcast unique to Bainbridge Island and Seattle Washington, that covers the Arts, Society & Culture told through Human Interest stories. The intent is to introduce interesting people, ideas, and conversations. We are not perfect and that's OK! Thank you for your support! The B.I.Stander Podcast is a listener supported show, please consider subscribing.   BE A FRIEND OF PODCASTVILLE AND TELL A FRIEND  The BISTANDER Podcast! Blue Canary Auto NOW ALSO in Bremerton! Sound Reprographics Intro Song "Fly on the Wall by LeRoy Bell and available at:  Tower Records! Additional sound effects by: https://www.zapsplat.com/ Support the Show on PATREON "Be a friend, tell a friend!"

In primary care, we are increasingly using FIT (Faecal Immunochemical Testing) to assess the risk of bowel cancer in patients with lower gastrointestinal symptoms, whilst the latest PCN DES IIF (Impact and Investment Fund) has given FIT a prominent role in risk stratifying 2-week wait referrals to secondary care. In this episode, Mo Thoufeeq, a gastroenterologist in Sheffield, talks to me about what FIT is, how it differs from previously used FOBT (and why it is a more effective test!), and how we are using FIT in both symptomatic and asymptomatic patients. He shares his top tips about how to interpret, when to test and we discuss the tricky areas of patients with rectal bleeding and those with iron deficient anaemia. Mo has a deep knowledge and understanding of FIT and provides a fantastic and relevant discussion of the topic for our primary care audience in this episode.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks… Let's get started!    Nycole: Hi Dr Cabral, I love the podcast and your positive energy, thank you for all your work!I have spots on my skin called CARP, confluent and reticulated papillomatosis. I have had them for 3 years, wondering where it comes from and what to do about it. I eat a mostly paleo diet and recently strictly gluten free due to celiac. Thanks! Rebecca: I'm looking for information on an elevated secretory IGa, my results were >6000 Anti-Gliiadin IgA was >500 Occult blood 77 I had a gi map test completed by a different company and I don't feel like they understood the results. I'm concerned about celiac and will start removing gluten from my diet. And get a FOBT from PCP. Just looking for more insight on the elevated IgAs Thank You so very much, I have spent a small fortune and don't feel like I got the best support or answers to my labs. The health coach said she had never seen such high IgA,s before As well I'm enrolled in the IHP 1&2 program, just signed up 2 weeks ago. Maria: Hi Dr. Cabral! I have a question in regards to vitamin D levels. I have had my levels tested 4 times over the last 9 months. I can't get my levels to budge from 30-35. I was supplementing with 5000 IU of the EquiLife drops and then bumped up to 10000 IU two months before my last test, but to no avail. I have listened to your podcast on the cofactors for vitamin D absorption many times. I use the DNS powder daily, so I'm getting all the other vitamins and minerals you mention in that podcast that are required for absorption. I had been taking my vitamin D at breakfast with my morning smoothie which contains 1-2 tablespoons of seeds. I just started taking it at lunch time instead and also started supplementing with additional K2 (MK7) at that time as well. I live in the Midwest, so sunlight vitamin D is really only possible from June-September. Not sure what else I can do to get my levels up. I am on month 1 of the CBO finisher, after completion of CBO protocol. I'm sure poor gut absorption has had something to do with it? Any other advice on how to get my levels up or why my levels haven't budged at all?! Do you have a favorite vitamin D light that you recommend? Karen: Dear Dr. Cabral, Thank you for your podcast and the easy way you get the information out about having good health. I am 62 and in the best health of my life thanks to many changes I have made. 10 years ago, I switched to a gluten free diet, the change it made in how I felt was amazing. Since then, I have been devouring books on health, and continuing to modify my diet and exercise. I am now dairy free, (a recent change) and eat very little sugar products. At 62 I am back to the weight I was when I graduated from high school! My question for you is about a condition I have on my lower lip, it has been there for about 25 years in varying degrees, and is called Actinic Cheilitis. It is a continual sloughing of skin cells on my lower lip, sometimes it is mildly painful, and is worse in the winter months. My dermatologist gave me a cream to treat it, a strong pharmaceutical that actually works by destroying the skin. I went through 1 round of this and couldn't tolerate the cream. The pain and ugliness on my lip was awful and I experienced body aches, headaches and couldn't sleep, a condition that is a rare side effect of this cream. As this is considered a pre-cancerous condition, I need to do something. I appreciate any suggestions you have. Dawn: I started the 7 day detox and after the 3rd shake, I felt nauseous? Is this normal? Should I continue on? Bettina: Hi Stephen thank you for your podcast, i only recently started listening to you. I got your rRain Barrel book and the 14 day detox. would love to have the tests done however with the $ exchange and taxes it get really expensive. can you suggest any labs in Brisbane or Gold Coast that you would recommend. looking forward to hearing from you. sincerely Bettina Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes & Resources:  http://StephenCabral.com/2200 - - - Dr. Cabral's New Book, The Rain Barrel Effect https://amzn.to/2H0W7Ge - - - Join the Community & Get Your Questions Answered: http://CabralSupportGroup.com - - -  Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Stress, Sleep & Hormones Test (Run your adrenal & hormone levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels)

For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:  ·PrevMed's website·PrevMed's YouTube channel·PrevMed's Facebook page

Interview: NICK RUST Chief Executive of the British Horseracing Authority talks to Simon Nott of his early love of horseracing and betting and his rise from a humble Ladbrokes board-marker. He covers conscientious issues such as bookmaker account restrictions, FOBT’s and the betting exchanges as well as the joys of being active in the sport as an owner. Meeting Nick Rust.

Interview: BRUCE MILLINGTON: We talk to the Racing Post’s editor Bruce Millington. He talks to Simon Nott of his early love for racing and betting, embryonic days as a journalist and his subsequent rise to top of the tree. He talks a host of topics and addresses criticism levelled at the paper, the FOBT debate, bookmaker restrictions and the positives and negatives of social media. Meeting Bruce Millington.

Matt Zarb-Cousin is a gambling activist. He has #livedexperience as someone who's experienced gambling harm. Matt is the Director of Clean Up Gambling Matt coordinates the Coalition Against Gambling Ads Matt is the co-founder of Gamban Matt was integral to getting FOBT's MAX BET reduced from 100 pounds to 2 pounds. Matt is a great person and I am pleased to bring you this conversation Please listen and learn from those who know. A better life without gambling. Join for an episode or simply say hello! - leestreetpod@gmail.com Please leave us a rating or review wherever you get your podcasts. It helps those still struggling to find us! Please support our sponsor - Gamban Music by T. Vance And if you are in the U.K. check out TalkBanStop

বাউয়েল ক্যান্সারের প্রাথমিক লক্ষণ সনাক্তকরণের জন্য স্ক্রিনিং অন্যতম কার্যকর উপায়। প্রথম দিকে লক্ষণ সনাক্ত করা গেলে,বেশিরভাগ ক্ষেত্রে এই ক্যান্সারের সফল চিকিৎসা করা যেতে পারে।কোভিড ১৯ এই মহামারীর সময়ে আপনি হয়তো আপনার অন্যানো বিষয়গুলোর সাথে এই বিষয়টিকে তেমন গুরুত্ব দিচ্ছেন না - যেমন আপনার বাউয়েল স্ক্রিনিং টেস্ট কিট।বাউয়েল (বা কোলোরেক্টাল) ক্যান্সারের কারণে ফুসফুসের ক্যান্সারের পরে অস্ট্রেলিয়ায় দ্বিতীয় সর্বোচ্চ সংখ্যক ক্যান্সারের মৃত্যুর কারণ হয়ে থাকে। তবে, প্রায় ৯০ শতাংশ এই বাউয়েল (বা কোলোরেক্টাল) ক্যান্সারের আক্রান্ত রোগীদের প্রাথমিক অবস্থার সনাক্ত করা গেলে নিরাময় সম্ভব ।ক্যান্সার কাউন্সিল অস্ট্রেলিয়া সুপারিশ করে যে ৫০-৭৪ বছর বয়সের অস্ট্রেলিয়ানরা প্রতি দুই বছর পরপর মলত্যাগের রক্ত ​​পরীক্ষা (FOBT) সম্পন্ন করে।স্বাস্থ্য বিষয়ের এই গুরুত্বপূর্ণ বিষয়টি নিয়ে এসবিএস বাংলার সাথে কথা বলেছেন ডাক্তার আয়াজ চৌধুরীকে যিনি Epidemiology ,Gastroenterology , endoscopy এবং Inflammatory Bowel Disease (IBD).বিশেষজ্ঞ। ৩৪ বছর ধরে অস্ট্রেলিয়ায় মেডিসিন প্রাকটিস করছেন এবং তিনি গত ২৩ বছর যাবৎ Senior Consultant Gastroenterologist হিসাবে Sydney west Area Health Service এ কাজ করছেন। এছাড়াও তিনি বাংলাদেশ ফোরাম ফর কমিউনিটি এনগেজমেন্ট এর ফাউন্ডার মেম্বার এবং দীর্ঘ সময় ধরে ক্যান্সার কাউন্সিল অফ নিউ সাউথ ওয়েলস এর জন্য ফান্ড রেসিং করছেন। ডাক্তার আয়াজ চৌধুরীর সাক্ষাৎকারটি শুনতে উপরের অডিও ক্লিপটিতে ক্লিক করুন।

Episode 15: Colorectal Cancer Screening The sun rises over the San Joaquin Valley, California, today is June 5, 2020.Have you heard about a new once-a-day gabapentinoid for postherpetic neuralgia? It’s called Gralise®. Keep it in mind, but also be mindful of the price. According to GoodRx, 30 tablets of 300 mg may cost $200 with a discount coupon. Consult your patient’s formulary to verify its coverage.On Tuesday, May 24, at 9:32 PM, a 3.7-magnitude earthquake was felt in east Bakersfield. The quake’s epicenter was estimated at Corrientes Street near Kern Medical, according to USGS. There was no damage, and the shaking was described as “light” and “a typical Californian earthquake”. This serves as a reminder for emergency preparedness. Make sure you have a plan and good home storage in case of a major event. Finally, something different than COVID-19 caught national attention on May 25, 2020. Unfortunately, it was not a positive note. An African-American man named George Floyd was killed by a policeman in Minnesota. This has caused national commotion and has heated up the debate about racism in the US. Hopefully by the time you listen to this episode, justice has been served.  Welcome to Rio Bravo qWeek, the podcast of the Rio Bravo Family Medicine Residency Program, recorded weekly from Bakersfield, California, the land where growing is happening everywhere.The Rio Bravo Family Medicine Residency Program trains residents and students to prevent illnesses and bring health and hope to our community. Our mission: To Seek, Teach and Serve. Sponsored by Clinica Sierra Vista, Providing compassionate and affordable care to patients throughout Kern and Fresno counties since 1971. “If you are not willing to learn, no one can help you. If you are determined to learn, no one can stop you.” –Zig Ziglar.If you are determined to learn, you are just unstoppable. Your residency experience can be enriched by your determination to learn. Dear residents, make sure your eagerness to learn works in your favor as a driving force during this unique period of your life. Today we have a resident with a strong determination to learn. She has successfully overcome many obstacles and she’s here with us today as a PGY3. Welcome, Dr Fareedy.Question number 1: Who are you?My name is Amna Fareedy. I am a third-year resident at Rio Bravo Family Medicine Residency Program in Bakersfield. I was born in New Jersey and moved to Pakistan during high school. I relocated back to the USA after finishing my medical school and getting married. I am also a mother to two very active children. My hobbies include reading and watching period dramas, but between my children and residency that has been on a halt for a while. My only entertainment at home currently is watching baby shark with my children.Question number 2: What did you learn this week? This week I learned about the different colorectal cancer screenings. As primary care physicians, preventive visits are very important for our patient’s well-being. At age 50, colorectal cancer screening becomes part of preventive care in average risk patients.  I have observed that patients can be hesitant in getting themselves screened for colorectal cancer (CRC) which can be due to number of reasons that I will highlight as we progress in discussion. Comment: This is a very good topic. I’m surprised to know that the American Cancer Society (ACS) recommends that people at average risk start screening at age 45 (2018). People who are in good health and with a life expectancy of more than 10 years should continue regular colorectal cancer screening through the age of 75. For ages 76-85, the decision to be screened should be based on a person’s preferences, life expectancy, overall health, and prior screening history. People over 85 should no longer get colorectal cancer screening. The USPSTF recommends screening at age 50 (2016, being revised).Three different ways to screen for colorectal cancerMultiple screening tests are available to detect CRC and adenomatous polyps which differ in sensitivity, specificity, availability, effectiveness, and cost.Stool-based test: Fecal immunochemical test (FIT) for blood in stoolsThis test directly measures the hemoglobin in stool. Test Procedure: FIT is a simple test performed on stool sample provided by the patient in a special collection container. It is performed annually.Advantages and disadvantagesIt is convenient and has a higher adherence rate. There are no pre-requisites to be completed prior to testing no dietary and medication restriction.Does not require bowel prep, sedation or anxiety of an invasive procedure.It requires only one sample as compared to the FOBT which requires three.It is more sensitive than gFOBT for colon lesions.When compared with gFOBT, FIT screening has higher detection rate for CRC and advanced adenomas due to higher sensitivity and higher screening participation rate with FITFIT is less sensitive for detection of right sided than left sided colon lesions.Comment: Screening for colorectal cancer = Screening for polyps.Multitargeted stool DNA test with FIT (Cologuard®) It is a composite of test that include assay to test for DNA KRAS mutations gene amplification to test for biomarkers associated with colorectal neoplasm, and to test for hemoglobin that might be shedding in to stool from the colon.Patient collects the stool in a special collection kit and mails it to the company for testing. It has to be received by the company within 72 hrs of collection.Advantages and disadvantages:Testing is done at home.No medical dietary restrictions. No bowel prep or sedation. If test is positive, then follow up with colonoscopy. If negative, follow up every three years instead of annually.Patient may not completely collect the full stool sample as instructed by collection kit.Stool sample needs to be received by the company within 72 hours of collection. Comment: In our clinic, all the MAs have the ordering form, just sign it and ask your MA to fax it. Patient will be contacted by manufacturer. You will get the result to discuss it with the patient. ColonoscopyIt is the most commonly used screening test in United states. It needs to be performed by trained clinician using endoscope to directly visualize the colon. It is performed every 10 years. Advantages and Disadvantages: Definite test for detection of precancerous adenomas and CRC with high sensitivity and specificity.It allows for biopsy to be taken. It requires vigorous bowel preparation.Sedation is used during colonoscopy.Patient might need another attendant on discharge due to sedation effect. Sedation related side effects.Colonoscopy related bowel injuries perforation bleeding.Less effective in detecting right sided compared to left side colon lesions because of contour or location.Comment: For the record, we did not cover flexible sigmoidoscopy, CT Colonography, Methylated SEPT9 DNA (mSEPT9), but those are other options to screen for colorectal cancer and adenomatous polyps. PolypsPedunculated and sessile: Both can turn into cancer, terms only describe the shape (mushroom-like or not). Hyperplastic, Hamartomatous, and inflammatory (normally not cancerous, only in certain cases – size, number, location and certain syndromes).Sessile serrated polyps or adenomatous polyps (considered precancerous polyps and require close surveillance). The GI specialist will normally give patients a follow up instruction. Question number 3: Why is that knowledge important for you and your patients?As primary care physicians, this knowledge is important so we can offer our patients all the options available for colorectal cancer screening. Limiting patients to one choice, for example colonoscopy, results in non-adherence due to different factors discussed earlier.Patients can be offered all the choices: FIT, FOBT, Cologuard®, sigmoidoscopy, etc. in addition to colonoscopy. If patient’s results are positive, further intervention and recommendations can be offered, which is better than not having any screening at all.Comment: Colorrectal cancer is the second leading cause of cancer death in the US, almost 50,000 patients die every year.Question number 4: How did you get that knowledge?Many of my patients are resistant to be screened for fears of colonoscopy. I want to offer them different options.Where did that knowledge come from?For this topic, I specifically read up-to-date test for screening for colorectal cancer, the ACS website, and USPSTF current recommendations.Speaking Medical (Medical word of the Week): Smegmaby Steven SaitoSmegma, also known as penile cottage cheese,is a white or yellowish secretion found between the glans of the penis and the foreskin of men and other mammals. It is an oily mix of sebum with dead cells that may become “cheesy and smelly” when left stagnant. The combination of warmth and smegma creates a rich breeding media where bacteria can grow and create a characteristic stench. This can lead to infections as well. Smegma is not exclusive to men as women also secrete smegma around the clitoris and labia minora. Believe it or not, smegma is essential for lubrication and good health of the genital organs. Just keep it under control with regular hygiene. An alternative definition by Urban dictionary is “a delicious butter substitute.” Espanish Por Favor (Spanish Word of the Week): Diarreaby Fermin GarmendiaHello, I am Dr Garmendia and I’m here with our section Espanish Por Favor. The Spanish word of the week is diarrea. When you see the spelling of this word, you can quickly realize it is diarrhea, but the pronunciation is different. Diarrea consists of watery or loose stools. The patient may present to you and tell you: “Doctor, tengo diarrea.” It is a common complaint among our patients, and you need to investigate the characteristics of the stools, any blood? Any mucus? Also, inquire about duration, frequency, triggers, and alleviating factors. Many of our patients relate diarrea to parasites or other infections, and you know it is not always the case. I invite you to read about the work up of diarrhea to learn more, but now you know the Spanish word of the day, diarrea.  For your Sanity (Medical Joke of the Week)by Steven SaitoLast week we gave you three questions and we got many good answers. We picked the first person who answered correctly and the winner of our contest is [drum roll] [SURAJ, ADD THE NAME HERE], congratulations! Here are the answers to our questions.For the treatment of acute cluster headache, in what nostril is it recommended you administer an intranasal triptan? Dr Manzanares explained that we should administer the intranasal triptan in the nostril contralateral to the symptoms of the acute cluster headache, i.e. if your headache is on the right side, administer Imitrex in the left nostril.What is the other term used for “wet-to-dry” dressings in wound care? Dr Tu recommended the use of the term “moist-to-dry” because the dressing should not be soaking wet, but just moist.Why do we use single-dose vaccine vials instead of multidose vaccine vials? Dr Saito explained that we use single dose vaccine vials to avoid use of thimerosal. Thimerosal is a mercury-containing preservative.Now we conclude our episode number 15 “Colorectal Cancer Screening”. Dr Fareedy explained the difference between FIT, Cologuard® and colonoscopy. Remember to offer different options to screen your patients who are 50 years and older for colon cancer. Smegma may not be the most elegant of the human body secretions, but it has many benefits. Personal hygiene is key to keep smegma under control and prevent disease. What’s diarrhea without an h? It’s the Spanish word diarrea (Suraj, pronounce dee-ah-RAY-ah). We are happy for [ADD NAME OF WINNER HERE] who is not only wiser for listening to this podcast but also $20 richer. This is the end of Rio Bravo qWeek. We say good bye from Bakersfield, a special place in the beautiful Central Valley of California, United States, a land where growing is happening everywhere.If you have any feedback about this podcast, contact us by email RBresidency@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. This podcast was created with educational purposes only. Visit your primary care physician for additional medical advice. Our podcast team is Hector Arreaza, Alyssa Der Mugrdechian, Fermin Garmendia, and Seven Saito. Audio edition: Suraj Amrutia. See you soon! _____________________References:American Cancer Society Guideline for Colorectal Cancer Screening, May 30, 2018, https://www.cancer.org/cancer/colon-rectal-cancer/detection-diagnosis-staging/acs-recommendations.html, accessed on May 28, 2020.Polyps, F!GHT Colorectal Cancer, https://fightcolorectalcancer.org/prevent/colon-polyps/ , accessed on May 28, 2020.  Colorrectal Cancer: Screening, US Preventive Services Task Force (USPSTF), https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening, accessed on May 28, 2020. Ahmed, Murtaza, “What is Smegma?: A Guide to the Unappetizing Biofluid That is Smegma”, July 1, 2015, Myheart.Net, https://myheart.net/articles/smegma/

Joe Squared discuss gambling and FOBT machines, the Better Call Saul actor who cut his own arm off, The Hunger Games films, Donald Trump's recent sanctions tweet and the health benefits of Guinness.Support this show http://supporter.acast.com/flavours-weekly. Hosted on Acast. See acast.com/privacy for more information.

Early in November, one lucky winner matched all five numbers and the Powerball to take home a $150 million jackpot. That ticket was purchased on the California side of Gold Ranch Casino and RV Resort in Reno, Nevada. The casino portion of the property is in Nevada while the lottery sales actually take place in California. The winner has the option of taking home $60 million after taxes. They can also spread out the total $130 million over 30 years. The winner has yet to come forward. They have one year from the date of the drawing to claim their money. GVC CEO Kenny Alexander Denounces Plan for Online SlotsBritain lawmakers were successful in getting the maximum bet on fixed-odds betting terminals (FOBT) lowered to two pounds. That new law took effect early this year. They have now turned their sites toward reducing the max bet on online slots to the same level. The voice of opposition is being led by GVC CEO Kenny Alexander. His company is one of the largest regulated online gaming operators in the world. The recent acquisition of Ladbrokes Coral as Britain’s biggest land-based bookmaker makes GVC the 20th-highest corporate tax payer. Alexander described the plan as “ridiculous”. He also said FOBT’s and online slots are “apples to oranges.”Trump’s Impeachment Odds Tied to Impeachment HearingsLast week, public hearings for the impeachment proceedings against Donald Trump got underway. The beleaguered president is under the gun once again. This time it is tied to a previous phone call to the Ukraine. He allegedly used an approved financial military aid package as political clout against Democratic challenger Joe Biden. The hearings will determine the House’s actions in the matter. Betting on the outcome of these hearings is available through prop bet odds at several prominent online sportsbooks.. The odds favor impeachment at 1/5 with 3/1 betting odds he will not be impeached by Congress.Resorts World Catskills Turns the Page With New OwnershipIn early February, shareholders of the Monticello-based Empire Resorts approved the sale of Resorts World Catskills. The buyer is a Malaysian-based gambling conglomerate. The new ownership group is made up of Kien Huat Reality and Genting Malaysia. The same group already owned Resorts World New York City in Queens. The sale was first announced in August with the current ownership struggling to meet financial projections. Resorts World Catskills faced a potential bankruptcy without the sale. Kien Haut Reality will own a controlling 51 percent stake. Genting Americas will own the remaining 49 percent private interest.

Dr Kristi Milley and Sophie Chima talk to Kate Broun, Manager - Screening, Early Detection and Immunisation at Cancer Council Victoria about the recent media campaign that was launched in March 2019 and the recent publication Impact of a mass media campaign on participation rates in a National Bowel Cancer Screening Program. This study aimed to compare bowel cancer screening rates prior to, during and after a mass media campaign, and assess how high intensity campaigning in one state compared to a state that received less campaign exposure. An eight-week television-led mass media campaign was launched in selected regions of Australia in mid-2014 to promote the National Bowel Cancer Screening Program (NBCSP), which mails out FOBT kits. The campaign used TV advertising in the entire state of Queensland (QLD) but only some of Western Australia (WA). There were other supportive campaign elements such as print, digital and online advertising. The number of FOBT kits returned increased in QLD during the months of the campaign and up to two months after the broadcast, but not significantly in WA. This study indicates that low levels of participation in the NBCSP could be increased by mass media campaigns, but the overall effect will be dependent on the intensity of the campaign. Show notes are available here . http://pc4tg.com.au/research-round-up-march-2019-kate-broun/

An investigation by BBC Radio 5 Live Investigates reveals problem gamblers are able to continue betting online even when they sign up to a national self-exclusion scheme. More than 50,000 people have signed up to the GamStop scheme which allows addicts to ban themselves from online betting platforms. But 5 Live Investigates recruits the son of a problem gambler to sign up to the scheme to test if it works. After banning himself, Adam Bradford, whose dad David lost more than £100,00 by gambling online, is able to sign up to a new gambling website by changing just a few small personal details. GamStop say they're 'deeply concerned' by the findings. The programme also returns to Grimsby where a year ago a producer self-excluded from all the high street bookies in the town. But he was able to place bets on high stakes fixed odds betting terminals (FOBT's) in all but two of the betting shops he was banned from. A year on, the programme returns to Grimsby to find out if anything has changed.

Colonoscopy can be an uncomfortable topic, but the fact is that it saves lives. Dr. Jennifer Lee discusses common excuses for not getting the test, who should be screened and why colonoscopy is so important.   TRANSCRIPT Intro: MedStar Washington Hospital Center presents Medical Intel where our healthcare team shares health and wellness insights and gives you the inside story on advances in medicine. Host: Thank you for joining us today. We’re talking with Dr. Jennifer Lee, a gastroenterologist at MedStar Washington Hospital Center. Welcome, Dr. Lee. Dr. Jennifer Lee: Hello. Thanks for having me. Host: Today we’re talking about colonoscopy and the national campaign 80 percent by 2018. The goal is to increase the colorectal cancer screening rate to at least 80 percent of eligible adults by the year 2018. Colonoscopy is the gold standard of colon cancer prevention and with regular screening, precancerous masses called polyps often can be removed before they turn into cancer. Dr. Lee, why do people avoid colonoscopy, a screening that can effectively prevent devastating colorectal cancer? Dr. Lee: I think for many reasons patients would avoid colonoscopy. One is maybe they don’t want to know. But I think the biggest reason is they find it to be uncomfortable, or, you know, who wants to come in and have something inserted in their backside? Host: Could you discuss why someone wouldn’t want to know? Dr. Lee: Yeah, I think some patients know that you maybe they have symptoms. Maybe they have a little bit of bleeding. Maybe they have a change in their bowel habits. And so they kind of suspect that something’s wrong, but, you know, you don’t want the devastating news of cancer, which is why screening colonoscopy is so important. We do it in asymptomatic individuals, and the goal is to prevent cancer. I often get asked, “Is colonoscopy the only way to screen for colon cancer?” And the answer is no. We have other noninvasive ways to screen for colon cancer, and they’re very good. But colonoscopy is a test of cancer detection, but also cancer prevention, and it’s because we’re able to take off polyps and prevent them from growing into colon cancers. Host: What are some of the alternatives if someone is really averse to colonoscopy? Dr. Lee: They’re mostly stool-based tests. Your primary care doctor can provide it. We provide it, as well. The oldest method which is fecal occult blood testing or, FOBT or otherwise known as guaiac testing. But there are better tests now and those include the FIT test and the Cologuard. Host: Are those tests done at home or at the doctor? Dr. Lee: They are done by providing a stool sample, so they are arranged through the doctor, but most patients just, sort of, do it at home. I think a misconception is that your doctor is supposed to take your stool sample with a rectal exam in the office, but it’s supposed to be a spontaneous stool sample. Host: How do you discuss colonoscopy and why it’s so important with your patients if they come in with fear or anxiety about the test? Dr. Lee: The way I describe it to my patients is the hardest part is the prep. You can’t eat the day before. You are drinking a laxative that potentially is not the best tasting laxative.  And then you have to stay by the toilet. And you know, I tell my patients to think of it as a cleanse and I think people get that. And then by the time you’re coming in, you just have an IV inserted and you get to take a nap. After you take your nap, you wake up, you’re done. So, it’s not as bad as people think it is. I think if you ask most of the patients in recovery, they will tell you that. “Yeah, it wasn’t that bad, it wasn’t as bad as I thought it was going to be,” and I’ve had patients say “I’m going to go tell my friends it wasn’t that bad. I’m going to send them all here.” As a field, gastroenterology is moving towards more advanced procedures in the care of colon cancer patients. And so, we do have experts—our advanced endoscopists—who can take care of advanced polyps, large polyps and even very, very early cancers. I’ll give you an example. I had a patient who came in for colonoscopy, average risk, completely no symptoms. You would not think that the patient had any...was at any increased risk for colon cancer. We did find a mass on colonoscopy that was suspicious for cancer. We took biopsies. The same day, I called the colorectal surgeon, and we were able to get them in to see the colorectal surgeon that same week. The pathology results were available the next day, and the patient had a curative resection for colon cancer. Host: When should a person of average risk of colon cancer start getting screened? Dr. Lee: Yeah, average-risk individuals should start getting screened at age 50 unless they’re African-American, in which case they should start their screening at age 45. Increased-risk individuals would include those with a family history of colon cancer. Those patients usually start their screening at age 40, or even before. Host: Why should African-Americans start earlier than other cultures? Dr. Lee: We’ve seen, epidemiologically that African-Americans are, more prone to colon cancer, and so therefore we want to prevent colon cancers. So, really focusing on preventive care, we want to catch them earlier. Host: If a patient has a loved one who should be screened, you know, because of their age or their risk factors, what advice could you give that individual to share with their loved one to help nudge them along and schedule that colonoscopy? Dr. Lee: You know, you think of it as any other cancer screening test—mammogram, you know, for women, GYN exams. It’s just like those, and it’s so important because you could prevent this potentially devastating disease. It’s absolutely preventable. So, while the thought of it may be displeasing, I think the end result is you are reassured and to know that you’re taking care of your body and making sure that you have a clean bill of health. Host: What do you feel is your role in the 80 percent by 2018 national campaign? Dr. Lee: Personally, this is day in and day out, this is what I do. I want to prevent colon cancer. I do colonoscopies. I remove polyps. That is, so much of what I do, and I’m such a big believer in preventive care that, you know, I feel very passionately about it. You know, I’m like a colonoscopy cheerleader. You know, like get your colonoscopy.  While it may seem a strange, topic to be excited about, it, nevertheless it’s—I am excited about it. If we could reach 80 percent, that’d be amazing, you know, and I think that, you would be saving lives, you would be saving healthcare dollars, for just, you know, one day of being hungry. You know, and I’ve done the one day of being hungry. It’s bad, but it’s, you know, you live through it, and then you can think about the meal that you’re about to have after your colonoscopy. Host: What do you feel needs to happen at a local or a national level to reach that 80 percent goal or even exceed it? Dr. Lee: You know, I think that having that part of, uh, general health be at the front of your...your mind. I think our primary care doctors are doing a great job of identifying who needs to be, screened, and so providing, access to colonoscopy, I think, is crucial. We do many of them, but there, you know, we need to do more.  And so, thinking about any patient that you are seeing --do they need to be screened, yes/no? And, if they do, send them over.  And, these days the prep is not as bad as it used to be. It’s a—we have lower volumes, better tasting things. Host: Are there any risks involved with colonoscopy? Dr. Lee: Sure. I think some patients are afraid of the complications of colonoscopy and absolutely there are complications, but I often tell them that they’re rare—the complications are quite rare--you know, 1 in 10,000, less than that even, and that’s a great aspect of having your procedure done at Washington Hospital Center. We are big believers in the multidisciplinary team approach, so we work closely with surgeons and other colleagues in case something does happen, but I should say that we are experts, we’re experts in colonoscopy, and we’re good at what we do, so patients are in good hands when they come see us. Host: Thanks for joining us today, Dr. Lee. Dr. Lee: Oh, thank you for having me. Conclusion: Thanks for listening to Medical Intel with MedStar Washington Hospital Center. Find more podcasts from our healthcare team by visiting medstarwashington.org/podcast or subscribing in iTunes or iHeartRadio.

Interview: ANDY MARGETT Andy found himself going from a small-staking horse racing punter and recreational on-line poker player to a self-confessed ‘compulsive gambler’ who could lose £1000 on a FOBT in one session. These losses were funded by credit cards and loans. On the precipice of financial and family ruin he sought help and pulled himself from the brink. In this brutally honest interview he tells his story and offers advice to people who may find themselves in a similar position. He concludes talking about the work he now does in that sphere and facing up to having a problem. (interview by Simon Nott)

Cancer Screening Cervical: Age 21-65 Cytology q3yrs, co-test q5 if normal. ASCCP guidelines (there is an app! Or PDF: http://www.asccp.org/Assets/51b17a58-7af9-4667-879a-3ff48472d6dc/635912165077730000/asccp-management-guidelines-august-2014-pdf ) Breast: ACOG: 40-75 annual mammogram Colon: Colonoscopy, FOBT, FIT. Begin at age 50. If first degree relative with colon cancer begin screening at age 40 or 10yrs prior to youngest diagnosis, whichever is younger. […]

Cancer Screening Cervical: Age 21-65 Cytology q3yrs, co-test q5 if normal. ASCCP guidelines (there is an app! Or PDF: http://www.asccp.org/Assets/51b17a58-7af9-4667-879a-3ff48472d6dc/635912165077730000/asccp-management-guidelines-august-2014-pdf ) Breast: ACOG: 40-75 annual mammogram Colon: Colonoscopy, FOBT, FIT. Begin at age 50. If first degree relative with colon cancer begin screening at age 40 or 10yrs prior to youngest diagnosis, whichever is younger. […]

In association with At The Races: Emmet Kennedy, Kevin Blake and Vanessa Ryle discuss the FOBT controversy and look ahead to this weekend's action at Newbury and Naas. Subscribe for free on Apple Podcast's, SoundCloud, Podcast Republic, Google Play and Android Podcast apps. If you're listening on an Apple device, we'd really appreciate a Five Star Rating on Apple Podcast's to help spread the word about the show. www.attheraces.com/finalfurlongpodcast Download on iTunes itunes.apple.com/ie/podcast/the-f…id601526577?mt=2

Theo Usherwood explains what we can expect from the Brexit transition period. Plus, Richard Suchet looks at FOBT's and whether they need to be better regulated. And we have everything you need to know about Cambridge Analytica.

I'm excited to be answering your questions this weekend and can't wait to get started with our first Cabral #HouseCall!   Here are today's communities questions:   Jenn: Hi Dr. Cabral! I will be traveling internationally within the next week and a half and am trying to pump my body up with extra goodness to prevent illness while abroad. I have been using your all in one shake (which is out of stock and I am running out!) and have increased my vitamin c. What else should I add into my daily regimen? Anything I should throw in my backpack besides the vitamin c to take along with me? I am on xarelto, my only medication, for Factor V Leiden, as I have had 2 PE's. I love to integrate natural supplements etc into my life, but am confused at times if they interact with this drug. Thank you so much for your insight!     Vrajhi: Hello Dr. Cabral. I want to first thank you for all that you do. My family has benefitted so much from your podcasts and products... I honestly don't know where we would be without you. That being said, I have a question about facial hair on females. Is it possible at all to get rid of unwanted facial hair growth? I am hoping that once my hormones get rebalanced that it will go away on its own. I have only been dealing with chin hair for maybe 2 or 3 years and it has gotten aggressively worse with everything I've tried to do to get rid of it (which includes waxing, plucking, electrolosis, hair removal creams, etc). Is there a silver lining?       Anon: Hello! My mom gets frequent sinus infections, at least 2x a year and takes antibiotics about 1-2x year for them. She is an elementary teacher and has bad allergies. I tell her not to take the antibiotics but she feels it is the only way she can function and get back to normal. They usually work. How can she wean off of this bad habit, and kick sinus infections naturally. Any advice much welcomed. Also a reminder of what antibiotics do to our bodies. Thank you!       Anon: Hello, My husband has been dealing with excess gas, bloating, mucous in his stool and frequent constpation. We are currently doing your OAT test and food sensitivity test, but I know that those symptoms match the symptoms for colon cancer. I was wondering what your take is on colonoscopies. I know there are real risks associated with the procedure. 1 in 1000 cause death. I've also read that the harsh laxatives they give before procedure cause gut imbalances and there are often false positives and finding/treating tumors that may heal themselves. Would an FOBT be sufficient? Would a simple blood test possibly show if there are any problems? Or is a colonoscopy necessary? Thanks for info       Susan: Hello Dr. Cabral I am an avid listener and love your show. I have learned so much. I am a 52 year old healthy female - approx 10 to 20 lbs overweight I have been active over the years but not consistently. I recently went through menopause and now my hips are aching and certain motions hurt. I went to the doctor and through xrays he says I have arthritis (not sure what kind - but I do have psoriasis) The pain although not severe is somewhat constant. I have no pain in any other joints and am still very flexible for my age. I am concerned about this as I feel 52 is young to start getting arthritis and I do not want to lose my mobility? Help do you have any suggestions. Susan     Ness: Hello! I just want to say thanks, your an absolute legend for sharing all this information for free. I wanted to ask if its possible to eat too much avocado in a day. I eat about 1-2 a day, is this okay because of its high fat content? I don't eat a lot of carbs and try to stay full from healthy fats. Thank you for the work you are doing in the world.   Enjoy your weekend and be sure to join us tomorrow for our 2nd Q&A of the weekend!   - - -    Show Notes:   http://StephenCabral.com/449   - - -   Get Your Question Answered:   http://StephenCabral.com/askcabral  

Episode 7: Colorectal Cancer Colon cancer is the second most commonly diagnosed cancer in Ontario and the second most common cause of cancer deaths.  You can check for colon cancer with a take home, fecal occult blood test (FOBT).  People of average risk of colon cancer should screen every 2 years between 50-74 years of age. People with a family history of colon cancer are at an increased risk and should be checked with a colonscopy.  Frank Pittman shares his story of how colon cancer affected his family and how he dedicates a major part of his life to helping other learning more about colon cancer prevention and screening.  Frank works with the Colorectal Cancer Association of Canada and can always be seen where The Giant Colon tour is.  Dr. Lawrence Hookey, the South East Regional Lead for GI Endoscopy, discusses different screening options, the risks and benefits of these and how patients can be best prepared to deal with colon cancer.    

Background/Aims: Surveillance colonoscopy is recommended afterpolypectomy of adenoma and surgery for colorectal cancer. The purpose ofthis study was to assess the frequency of advanced adenoma and cancer incolonoscopies performed for surveillance compared to screeningcolonoscopies. Methods: Analysis of relative frequencies of findings incolonoscopies performed for post-adenoma surveillance (post-ad),post-cancer surveillance (post-crc), screening, and follow-up of apositive fecal occult blood test (FOBT). Logistic regression was used toidentify the risk for advanced adenoma (adenoma mm, containinghigh-grade dysplasia, or villous histology) and cancer. Results: 324,912 colonoscopies were included in the analysis: 81,877 post-ad, 26,89 6post-crc, 178,305 screening, 37,834 positive FOBT. Advanced adenoma(cancer) was diagnosed in 8.0% (0.4%) of post-ad, 5.0% (1.0%) ofpost-crc, 7.4% (1.1%) of screening, and 11.7% (3.6%) of positiveFOBT colonoscopies. Compared to screening, the odds ratios for findingadvanced adenoma were 0.93 (95% CI 0.88-0.98) for post-ad, 0.96(0.86-1.08) for post-crc, and 1.18 (1.09-1.28) for positive FOBTcolonoscopies. The odds ratios for the diagnosis of cancer were 0.29(0.24-0.36) for post-ad, 0.81 (0.61-1.07) for post-crc, and 2.77(2.43-3.17) for positive FOBT. Conclusion: Colonoscopy for post-adsurveillance but not colonoscopy for post-crc surveillance is associatedwith a lower risk of diagnosis of advanced adenoma and cancer.

Colorectal cancer (CRC) is one of the leading causes of cancer related morbidity and death. Despite the fact that the mean age at diagnosis of CRC is lower in men, screening by colonoscopy or fecal occult blood test (FOBT) is initiated at same age in both genders. The prevalence of the common CRC precursor lesion, advanced adenoma, is well documented only in the screening population. The purpose of this study was to assess the risk of advanced adenoma at ages below screening age. We analyzed data from a census of 625,918 outpatient colonoscopies performed in adults in Bavaria between 2006 and 2008. A logistic regression model to determine gender- and age-specific risk of advanced neoplasia was developed. Advanced neoplasia was found in 16,740 women (4.6%) and 22,684 men (8.6%). Male sex was associated with an overall increased risk of advanced neoplasia (odds ratio 1.95; 95% confidence interval, CI, 1.91 to 2.00). At any age and in any indication group, more colonoscopies were needed in women than in men to detect advanced adenoma or cancer. At age 75 14.8 (95% CI, 14.4-15.2) screening, 18.2 (95% CI, 17.7-18.7) diagnostic, and 7.9 (95% CI, 7.6-8.2) colonoscopies to follow up on a positive FOBT (FOBT colonoscopies) were needed to find advanced adenoma in women. At age 50 39.0 (95% CI, 38.0-40.0) diagnostic, and 16.3 (95% CI, 15.7-16.9) FOBT colonoscopies were needed. Comparable numbers were reached 20 and 10 years earlier in men than in women, respectively. At any age and independent of the indication for colonoscopy, men are at higher risk of having advanced neoplasia diagnosed upon colonoscopy than women. This suggests that starting screening earlier in life in men than in women might result in a relevant increase in the detection of asymptomatic preneoplastic and neoplastic colonic lesions.