Podcasts about Exclusion

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Best podcasts about Exclusion

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Latest podcast episodes about Exclusion

The Score
The Essence of Exclusion

The Score

Play Episode Listen Later Jul 29, 2025 94:34


Happy Tuesday, Scorekeepers! It's time for another episode of your favorite podcast, THE SCORE! This week, we examine the strange turn to the right taken by several Black American celebrities and institutions of late. From Laverne Cox coyly revealing her MAGA ex-boyfriend to the backlash to this year's Essence Festival, it seems like there are some influential Black people who are using their platforms to (both wittingly and unwittingly) parrot conservative talking points, prop up the broken status quo, and/or create division between different members of the African diaspora. And it seems rather sinister and frustrating and unnecessary! So let's talk about it. But don't fret, because after that we have a nice, long Pure Black Joy to get us back to homeostasis. Let's do it to it, y'all!Hosts: Lee Bynum, Rocky Jones, Paige ReynoldsProducer: Rocky Jones--Hey hey, THE SCORE is now on social! Follow us @thescorepod on Instagram here and Bluesky here! --New episodes of THE SCORE drop every other Tuesday. If you like what you hear, please support us and SUBSCRIBE to the show on your favorite podcast app and be sure to SHARE our show with your friends. Also, leaving a 5-star REVIEW on Apple Podcasts, Spotify or wherever you're listening is a great way to help people find our show. Email your questions or comments to thescorepodcast2.0@gmail.com.Ways to Listen: Apple | Spotify | YouTubeFollow Your Hosts on Insta! Lee | Paige | Rocky

PLRB on Demand
Sugar, Spice, and Everything Sand: The CGL Auto Exclusion

PLRB on Demand

Play Episode Listen Later Jul 29, 2025 20:02


A concrete foundation is crumbling due to a truck's sugar-contaminated sand delivery. Now, a court case hinges on whether the CGL auto exclusion applies: Did the damage occur in the truck or on the job site? Notable Timestamps [ 00:30 ] - At the outset, it seems the question (of whether the CGL or the BAC policy applies) turns on whether the damage occurred on the job site, at the concrete plant, or on the sand delivery truck. [ 05:01 ] - Sugar can be used in small, controlled amounts to delay concrete setting time, but higher concentrations can prevent proper curing. The contamination in this scenario was due to a "failure to clean" the truck from a previous job. [ 08:57 ] - The CGL Auto Exclusion operates to ensure coverage falls under the proper policy. In this case, the property damage occurred on a truck, so it should not be handled by the CGL policy but by Business Auto Coverage. [ 13:02 ] - The CGL form defines property damage to include "loss of use", meaning that even if the sand itself wasn't physically damaged, its inability to be used for its intended purpose (making proper concrete) qualifies as property damage. [ 15:47 ] - The Business Auto policy "Care, Custody, and Control" exclusion applied because the concrete plant's employee made the error. [ 16:24 ] - Brennan provides a recap of the scenario and the points above. Your PLRB Resources In Brief: Clear Blue Specialty Ins. Co. v. Landrieu Concrete and Cement Industries, LLC, 2025 U.S. App. LEXIS 10563 (5th Cir. La. 5/1/25). https://www.plrb.org/documents/clear-blue-specialty-ins-co-v-landrieu-concrete-and-cement-industries-llc-2025/ Annotation: CGL Policy Key GL39 – Automobile Exclusion. https://www.plrb.org/documents/gl39-automobile-exclusion Employees of member companies also have access to a searchable legal database, hundreds of hours of video trainings, building code materials, weather data, and even the ability to have your coverage questions answered by our team of attorneys (https://www.plrb.org/ask-plrb/) at no additional charge to you or your company. Subscribe to this Podcast Your Podcast App - Please subscribe and rate us on your favorite podcast app YouTube - Please like and subscribe at @plrb LinkedIN - Please follow at “Property and Liability Resource Bureau” Send us your Scenario! Please reach out to us at 630-509-8704 with your scenario! This could be your “adjuster story” sharing a situation from your claims experience, or a burning question you would like the team to answer. In any case, please omit any personal information as we will anonymize your story before we share. Just reach out to scenario@plrb.org.  Legal Information The views and opinions expressed in this resource are those of the individual speaker and not necessarily those of the Property & Liability Resource Bureau (PLRB), its membership, or any organization with which the presenter is employed or affiliated. The information, ideas, and opinions are presented as information only and not as legal advice or offers of representation. Individual policy language and state laws vary, and listeners should rely on guidance from their companies and counsel as appropriate. Music: “Piece of Future” by Keyframe_Audio. Pixabay. Pixabay License. Font: Metropolis by Chris Simpson. SIL OFL 1.1. Icons: FontAwesome (SIL OFL 1.1) and Noun Project (royalty-free licenses purchased via subscription). Sound Effects: Pixabay (Pixabay License) and Freesound.org (CC0).

Land & Livestock Report
China Suspends Tariff Exclusion for U.S. Ag Products

Land & Livestock Report

Play Episode Listen Later Jul 28, 2025


China Suspends Tariff Exclusion for U.S. Ag Products

For the Life of the World / Yale Center for Faith & Culture
How Striving to Be Better Than Others Makes Us Worse / Miroslav Volf

For the Life of the World / Yale Center for Faith & Culture

Play Episode Listen Later Jul 23, 2025 33:54


What if our relentless drive to be better than others is quietly breaking us?Miroslav Volf unpacks the core themes of his 2025 book, The Cost of Ambition: How Striving to Be Better Than Others Makes Us Worse. In this book, Volf offers a penetrating critique of comparison culture, diagnosing the hidden moral and spiritual wounds caused by competition and superiority.Drawing on Scripture, theology, philosophy, literature, and our culture's obsession with competition and superiority, Volf challenges our assumptions about ambition and identity—and presents a deeply humanizing vision of life rooted not in being “the best,” but in receiving ourselves as creatures made and loved by God.From Milton's depiction of Satan to Jesus' descent in Philippians 2, from the architectural rivalry of ancient Byzantium to modern Olympic anxieties, Volf invites us to imagine a new foundation for personal and social flourishing: a life free from striving, rooted in love and grace.Highlights“The key here is for us to come to appreciate, affirm, and—importantly—love ourselves. Love ourselves unconditionally.”“Striving for superiority devalues everything we have, if it doesn't contribute to us being better than someone else.”“The inverse of striving for superiority is internal plague by inferiority.”“In Jesus, we see that God's glory is not to dominate but to lift up what is low.”“We constantly compare to feel good about ourselves, and end up unsure of who we are.”“We have been given to ourselves by God—our very existence is a gift, not a merit.”Helpful Links and ResourcesVisit faith.yale.edu/ambition to get a 40-page PDF Discussion Guide and Full Access to 7 videosThe Cost of Ambition by Miroslav Volf (Baker Academic, May 2025)Philippians 2:5–11 (NIV) – Christ's Humility and Exaltation – BibleGatewayRomans 12:10 – “Outdo one another in showing honor” – BibleHubParadise Lost by John Milton – Project GutenbergParadise Regained by John Milton – Project GutenbergShow NotesOpening Reflections on CompetitionThe conversation begins with Volf recalling a talk he gave at the Global Congress on Christianity & Sports.He uses athletic competition—highlighting Lionel Messi—as a lens for questioning the moral value of striving to be better than others.“Sure, competition pulls people up—but it also familiarizes us with inferiority.”“We compare ourselves to feel good… but end up feeling worse.”Introduces the story of Justinian and Hagia Sophia: “Oh Solomon, I have outdone you.”Rivalry, Power, and InsecurityShares the backstory of Juliana's competing church and the gold-ceiling arms race with Justinian.“Religious architecture became a battlefield of status.”Draws insight from these historic rivalries as examples of how ambition pervades religious life—not just secular.Modern Parallels: Yale Students's & the Rat RaceVolf notes how even Yale undergrads—once top of their class—feel insecure in comparison to peers.“They arrive and suddenly their worth plummets. That's insane.”The performance-driven culture makes stable identity nearly impossible.Biblical Illustration: Kierkegaard's LilyVolf recounts Kierkegaard's retelling of Jesus's lily parable.A bird whispers to the little lily that it's not beautiful enough, prompting the lily to uproot itself—and wither.“The lesson: we are destined to lose ourselves when our value depends on comparison.”Intrinsic Value and the Image of God“We need to discover the intrinsic value of who we are as creatures made in the image of God.”Kierkegaard and Jesus both show us the beauty of ‘mere humanity.'“You are more glorious in your humanity than Solomon in his robes.”Theological Anthropology and Grace“We have been given to ourselves by God—our lives are a gift.”“We owe so much to luck, to others, to God. So how can we boast?”Paul's challenge in 1 Corinthians: “What do you have that you have not received?”Milton and Satan's AmbitionShifts to Paradise Lost: Satan rebels because he can't bear not being top.“Even what is beautiful becomes devalued if it doesn't prove superiority.”In Paradise Regained, Satan tempts Jesus to be the greatest—but Jesus refuses.Christ's Humility and Downward GloryHighlights Philippians 2: Jesus “emptied himself… took the form of a servant.”“God's glory is not domination—it's lifting up the lowly.”“Salvation comes not through seizing status, but through relinquishing it.”Paul's Vision of Communal HonorRomans 12:10: “Outdo one another in showing honor.”“True honor comes not from climbing over others, but from lifting them up.”Connects this ethic to Paul's vision of church as an egalitarian body.God's Care for Creation and HumanityLuther's observation: God calls Earth good but not Heaven—“God cares more for our home than his own.”“We are called to emulate God's loving attention to the least.”Striving vs. AcceptanceVolf contrasts ambition with love: “The inverse of striving for superiority is the plague of inferiority.”Encourages unconditional self-love as a reflection of God's love.Uses image of a parent greeting a newborn: “You've arrived.”A Vision for Healed Culture“We wreck others in our pursuit of superiority—and we leave them wounded in our wake.”The gospel reveals a better way: not performance, but grace.“Our salvation and our culture's healing lie in the humility of Jesus.”“We must rediscover the beauty of our mere humanity.”About Miroslav VolfMiroslav Volf is the founding director of the Yale Center for Faith & Culture and the Henry B. Wright Professor of Theology at Yale Divinity School. One of the leading public theologians of our time, he is the author of numerous books including Exclusion and Embrace, Flourishing, A Public Faith, Life Worth Living, and most recently, The Cost of Ambition. His work explores themes of identity, reconciliation, human dignity, and the role of faith in a pluralistic society. He is a frequent speaker around the world and has advised both religious and civic leaders on matters of peace and justice.Production NotesThis podcast featured Miroslav VolfEdited and Produced by Evan RosaHosted by Evan RosaProduction Assistance by Macie Bridge and Taylor CraigA Production of the Yale Center for Faith & Culture at Yale Divinity School https://faith.yale.edu/aboutSupport For the Life of the World podcast by giving to the Yale Center for Faith & Culture: https://faith.yale.edu/give

The Podcast of Jewish Ideas
69. American-Israeli Thought | Dr. Adam Ferziger

The Podcast of Jewish Ideas

Play Episode Listen Later Jul 22, 2025 78:32


J.J. and Dr. Adam Ferziger crisscross the Atlantic to better understand the influence of American Orthodoxy on Israel, and vice versa. Buy the book: Agents of Change by Dr. Adam FerzigerFollow us on Bluesky @jewishideaspod.bsky.social for updates and insights!Please rate and review the the show in the podcast app of your choice.We welcome all complaints and compliments at podcasts@torahinmotion.org  For more information visit torahinmotion.org/podcastsAdam S. Ferziger holds the Rabbi Samson Raphael Hirsch Chair in the Israel and Golda Koschitzky Department of Jewish History and Contemporary Jewry at Bar-Ilan University. He is coconvener of the Oxford Summer Institute on Modern and Contemporary Judaism, University of Oxford. Ferziger is a scholar of Jewish religious culture in the U.S. and Israel. His research focuses on the history of Jewish religious responses to modern and contemporary life.He is the author or editor of eight books including: Exclusion and Hierarchy: Orthodoxy, Nonobservance and the Emergence of Modern Jewish Identity (University of Pennsylvania Press, 2005) and Beyond Sectarianism: The Realignment of American Orthodox Judaism (Wayne State University Press, 2015), which received the 2015 National Jewish Book Award. His new monograph, Agents of Change: American Jews and the Transformation of Israeli Judaism (NYU Press, 2025), will be available from July 2025.Ferziger received his B.A., M.A., and rabbinical ordination from Yeshiva University, and, after moving to Israel in 1987, his Ph.D. from Bar-Ilan.

ASIAN AMERICA: THE KEN FONG PODCAST
EP 545: Michael Luo On "Strangers in the Land: Exclusion, Belonging & the Epic Story of Chinese in America"

ASIAN AMERICA: THE KEN FONG PODCAST

Play Episode Listen Later Jul 20, 2025 52:20


Michael Luo is an executive editor at The New Yorker and writes regularly on politics, religion, and Asian American issues. His first book, “Strangers in the Land: Exclusion, Belonging, and the Epic Story of the Chinese in America,” is a well-researched history of Chinese Americans from the Gold Rush until the 1960s. Using his skills as a former investigative reporter, Luo manages to bring back to life the myriad Chinese Americans who struggled, suffered, and even were murdered in their persistent efforts to make this strange new land a new home for themselves and for those who would one day follow in their footsteps.

Peake Mennonite Church
Excuses That Lead To Exclusion 7-20-25 Dave Miller

Peake Mennonite Church

Play Episode Listen Later Jul 20, 2025 33:22


Missions to Movements
How Tiffany Yu Turned Her Story Into a Movement for Disability Inclusion

Missions to Movements

Play Episode Listen Later Jul 16, 2025 34:15 Transcription Available


The global disability market represents a staggering $18 trillion dollars in spending power. And in this powerful episode, Tiffany Yu, founder of Diversability, TEDx speaker, and author of The Anti-Ableist Manifesto is sharing how she turned her own disability into a global movement for inclusion. After a car accident made her disabled and took her father's life, Tiffany eventually found the courage more than a decade later to share her story, helping others unlearn shame and embrace their own identities.You'll hear how Tiffany built Diversability from a college club into a thriving international community, why employers must rethink job descriptions and office norms to foster true accessibility, and how storytelling paired with data can radically shift public perception.If you want to build more inclusive communities, Tiffany's magnetic energy and practical wisdom will inspire you to see lived experience as a superpower rather than a limitation.Resources & LinksConnect with Tiffany on her website, order her book, The Anti-Ablelist Manifesto, and watch her TED talk, The Power of Exclusion.  This show is brought to you by iDonate. Your donation page is leaking donors, and iDonate's new pop-up donation form is here to fix that. See it in action. Launch the interactive demo here and experience how a well-timed form captures donors in the moment they care most. Let's Connect! Send a DM on Instagram or LinkedIn and let us know what you think of the show! My book, The Monthly Giving Mastermind, is here! Grab a copy here and learn my framework to build, grow, and sustain subscriptions for good. Want to book Dana as a speaker for your event? Click here!

YourForest
163-Breaking the Silence: Workplace Culture Challenges and Change in Forestry with Kelly Cooper & Greg Herringer

YourForest

Play Episode Listen Later Jul 16, 2025


In this episode of YourForest Podcast, host Matthew Kristoff is joined by Kelly Cooper, founder of the Free to Grow in Forestry initiative, and Greg Herringer, chair of the Canadian Institute of Forestry's DEI leadership team. Through honest and eye-opening conversation, they unpack why change is so difficult, highlighting deep-rooted resistance, fear of change, and power dynamics that hold progress back. Kelly shares her personal experience of being excluded from the very DEI work she was leading, while Greg reflects on how bias shows up in both personal and professional spaces.

Kroyi munsem
"Current NPP Executives Must Be Dissolved ASAP"- Nana Kwadwo Jantuah Responds To Kufuor's Exclusion Comment.

Kroyi munsem

Play Episode Listen Later Jul 13, 2025 100:53


"The NPP party's collapse and loss of appeal are clear. To rebuild trust, all party executives—from Afenyo Markins to Annoh-Dompreh—must be dissolved. Former President Kufuor has worked tirelessly for the party and doesn't deserve to be sidelined."

New Discourses
Exclusion as the Basis of Wealth

New Discourses

Play Episode Listen Later Jul 11, 2025 18:32


New Discourses Bullets, Ep. 119 We're inundated with messages that somehow "diversity is our strength" and the path to that strength and growth is through "inclusion." We also know that term is a Communist scam, and we've talked about that at length in the past, repeatedly. Well, it's time for a defense of exclusion as it is rightly meant by Communists, specifically the "fundamental right to exclude," which is a pillar of what defines private property. In this episode of New Discourses Bullets, host James Lindsay explains how this property, the fundamental right to exclude, is the basis for all wealth. It's not just an important episode to catch but one that's crucial to share with your kids who aren't getting these lessons at school. New book! The Queering of the American Child: https://queeringbook.com/ Support New Discourses: https://newdiscourses.com/support Follow New Discourses on other platforms: https://newdiscourses.com/subscribe Follow James Lindsay: https://linktr.ee/conceptualjames © 2025 New Discourses. All rights reserved. #NewDiscourses #JamesLindsay #exclusion

CCO Medical Specialties Podcast
Conversations in Chronic Cough: An Otolaryngologist's Perspective

CCO Medical Specialties Podcast

Play Episode Listen Later Jul 11, 2025 18:07


Listen as Michael S. Benninger, MD, describes his approach to the diagnosis and management of chronic cough and refractory chronic cough in the context of a clinically relevant case.PresenterMichael S. Benninger, MDProfessor of Otolaryngology-Head and Neck SurgeryLerner College of MedicineThe Cleveland ClinicPresident, International Association of PhonosurgeryCleveland, OhioLink to full program:https://bit.ly/4kweynG

Esprits Libres
Attentat déjoué d'un « incel » : « c'est la même chose que la radicalisation en ligne, c'est une auto-exclusion » selon Sophie Obadia

Esprits Libres

Play Episode Listen Later Jul 3, 2025 12:26


Un projet d'attentat a été déjoué le mardi 1er juillet à Saint-Etienne, avec l'arrestation d'un jeune homme âgé de 18 ans. Le suspect se revendique « incel », pour « involuntary celibate », une mouvance masculiniste et misogyne. Anne de Guigné et Sophie Obadia reviennent sur cet événement, ainsi que les motivations du jeune homme. Mention légales : Vos données de connexion, dont votre adresse IP, sont traités par Radio Classique, responsable de traitement, sur la base de son intérêt légitime, par l'intermédiaire de son sous-traitant Ausha, à des fins de réalisation de statistiques agréées et de lutte contre la fraude. Ces données sont supprimées en temps réel pour la finalité statistique et sous cinq mois à compter de la collecte à des fins de lutte contre la fraude. Pour plus d'informations sur les traitements réalisés par Radio Classique et exercer vos droits, consultez notre Politique de confidentialité.Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

KASIEBO IS NAKET
Numo Blafo Unbothered by Traditionalists' Exclusion from National Prayers, Calls For Unity

KASIEBO IS NAKET

Play Episode Listen Later Jul 2, 2025 48:10


Ghanaians observed National Prayers and Thanksgiving Day with Christian and Islamic leaders present, while traditionalists were not officially invited. Nuumo Blafo expressed no grievance, emphasizing unity and respect for all faiths and welcoming everyone regardless of invitation

RNZ: Saturday Morning
Intellectually disabled twice as likely to live in hardship

RNZ: Saturday Morning

Play Episode Listen Later Jun 27, 2025 10:13


Next Tuesday the IHC - which advocates for the rights, inclusion and welfare of people with intellectual disabilities will offiicially launch its new report entitled The Cost of Exclusion.

Then & Now
The Sociolinguistics of Exclusion: Affirmative Action, DEI, and the Struggle for Belonging. A Conversation with Jamaal Muwwakkil.

Then & Now

Play Episode Listen Later Jun 25, 2025 49:24


In this episode of then & now, we are joined by Dr. Jamaal Muwwakkil, Chancellor's Postdoctoral Fellow at UCLA and incoming Assistant Professor of Anthropology at the University of Washington, to discuss the recent rollback of affirmative action and diversity, equity, and inclusion (DEI) initiatives in American universities. Jamaal examines how these changes—set in motion by the Supreme Court's 2023 decision to end race-conscious admissions, alongside a rising political backlash against DEI, particularly from the Trump administration—signal a return to exclusionary practices after decades of hard-fought progress. Bringing a sociolinguistic perspective to the jagged history of Black student experiences in the era of affirmative action, Jamaal traces the arc from the first efforts at inclusion in the 1950s to the present moment. Focusing on the implications of these shifts, particularly for Black and Latinx students navigating the current higher education environment, Jamaal provides insight into how language, policy, and power shape experiences of belonging and exclusion on campus, offering essential context for understanding this pivotal moment in higher education.Dr. Jamaal Muwwakkil is a University of California Chancellor's Postdoctoral Fellow at UCLA in the Department of Education and Information Studies and an incoming Assistant Professor of Anthropology at the University of Washington. Jamaal holds a Linguistics PhD from the University of California, Santa Barbara. He was also the 2019-20 University of California (UC) Student Regent-designate and the 2020-21 UC Student Regent. Jamaal's research specializations include African American language and culture, sociocultural linguistics, and political discourse.

Cardiology Trials
Review of the CHARM-Alternative trial

Cardiology Trials

Play Episode Listen Later Jun 24, 2025 10:03


THE LANCET 2003;362:772-776Background: Angiotensin converting enzyme inhibitors (ACEi) reduce mortality and morbidity in patients with systolic heart failure (see CONSENSUS and SOLVD trials). However, registry data showed that up to 20% of patients with systolic heart failure were not taking ACEi. One of the frequent causes for intolerance to ACEi is cough. Angiotensin converting enzyme inhibitors work by blocking the conversion of angiotensin I to angiotensin II, a key step in the renin–angiotensin–aldosterone system (RAAS). Angiotensin II receptor blockers were tolerated in patients with systolic heart failure who were intolerant to ACEi. However, data on long term effectives as an alternative to ACEi were lacking.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.The Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM)-Alternative trial sough to assess if the angiotensin-receptor blocker (ARB) candesartan, could improve outcomes in patients with systolic heart failure who are intolerant to ACEi.Patients: Eligible patients had left ventricular ejection fraction of 40% or less and NYHA class II, III or IV symptoms of at least 4 weeks duration. Patients had also to be intolerant to ACEi.Exclusion criteria were not provided in the main manuscript.Baseline characteristics: Patients were recruited from 618 centers in 26 countries. The trial randomized 2,028 patients – 1,013 randomized to receive candesartan and 1,015 to receive placebo.The average age of patients was 67 years and 68% were men. The average left ventricular ejection fraction was 30%. Cardiomyopathy was ischemic in 68% of the patients. The NYHA class was II in 48% of the patients, III in 49% and IV in 4%.Approximately 50% had hypertension, 27% had diabetes, 61% had prior myocardial infarction, 9% had stroke, 25% had atrial fibrillation and 14% were current smokers.At the time of enrollment, 85% were taking a diuretic, 46% were taking digoxin, 55% were taking beta-blockers and 24% were taking spironolactone.The most common reasons for ACEi intolerance were cough in 72% of the patients, hypotension in 13%, renal dysfunction in 12% and angioedema or anaphylaxis in 4%.Procedures: The trial was double-blinded. Patients were assigned in a 1:1 ratio to receive candesartan starting at 4 or 8mg once daily or placebo. The treatment was doubled every two weeks to a target dose of 32mg once daily.After randomization, follow up occurred at 2, 4, and 6 weeks, 6 months and every 4 months thereafter.Endpoints: The primary outcome was a composite of cardiovascular death or heart failure hospitalizations. All deaths were classified as cardiovascular unless there was a clear non-cardiac cause.Analysis was performed based on the intention-to-treat principle. The estimated sample size to have 80% power at 5% alpha was 2,000 patients. The sample size calculation assumed 18% relative risk reduction in the primary outcome with candesartan assuming a 15% annual event rate in the placebo arm.Results: The median follow up time was 34 months. The mean candesartan daily dose was 23mg at 6 months.Candesartan reduced the primary endpoint of cardiovascular death or heart failure hospitalizations (33.0% vs 40.0%, adjusted HR: 0.70, 95% CI: 0.60 – 0.81; p< 0.001). Candesartan reduced the individual components of the primary outcome - (21.6% vs 24.8%; p= 0.02) for cardiovascular death and (20.4% vs 28.2%; p< 0.001) for heart failure hospitalizations. All-cause death was also lower with candesartan (26.2% vs 29.2%, adjusted HR: 0.83, 95% CI: 0.70–0.99; p= 0.033). The number of patients who had any hospitalization as well as the total number of hospitalizations were numerically but not statistically significantly lower with candesartan (60.2% with candesartan vs 63.3%; p= 0.16) and (1,718 vs 1,835; p= 0.06).Candesartan was associated with more hypotension (3.7% vs 0.9%), more increase in creatinine (6.1% vs 2.7%) and more hyperkalemia (1.9% vs 0.3%). Angioedema occurred in three patients in the candesartan group and none in the placebo group. Cough occurred in two patients taking candesartan and four taking placebo.Authors reported no significant subgroup interactions, however, a corresponding graph was not provided.Conclusion: In patients with systolic heart failure who are intolerant to ACEi, candesartan reduced the primary composite outcome of cardiovascular death or heart failure hospitalizations with a number needed to treat of approximately of 14 patients over 34 months of follow up. Candesartan also reduced all-cause death with a number needed to treat of approximately 33 patients. Adverse events including hypotension, increase in creatinine and hyperkalemia were more common with candesartan.The reduction in the primary endpoint with candesartan was significant and offers an alternative for patients who are unable to tolerate ACEi. Of note, 72% of the patients enrolled in the trial were intolerant to ACEi due to cough. This trial did not include a head-to-head comparison between ARBs and ACEi, and therefore does not address which agent should be preferred as first-line therapy. Only 24% of participants were receiving spironolactone. The combination of ARBs with spironolactone, may increase the risk of adverse events, particularly hyperkalemia and kidney injury.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

Voices of Montana
Physical Therapists Concerned Reimbursement Rates May Force Patient Exclusion, Clinic Closures

Voices of Montana

Play Episode Listen Later Jun 24, 2025 37:52


Montana physical therapists are concerned that Medicaid reimbursement rates are not meeting even the cost of their care, and that a bipartisan bill was recently vetoed that would have made some key adjustments. Click on the podcast to hear from […] The post Physical Therapists Concerned Reimbursement Rates May Force Patient Exclusion, Clinic Closures first appeared on Voices of Montana.

Tom Nelson
Ronan Connolly/Gerry Quinn:  “COVID-19 Pandemic: Lessons Learned” | Tom Nelson Pod #313

Tom Nelson

Play Episode Listen Later Jun 22, 2025 127:42


Ronan is an independent scientist, environmentalist and writer.About Gerry: My main interests are in disease, immunity and the discovery of chemotherapeutic compounds00:00 Introduction and Guest Introduction00:15 Overview of the COVID-19 Paper02:36 Background of the Authors and Initial Work03:27 Scientific Approach to COVID-1904:58 Challenges in Questioning the Science09:38 Government Policies and Model Predictions17:44 Sweden's Unique Approach20:32 Publication Challenges and Shifting Narratives22:14 Unintended Consequences of Policies26:27 Precautionary Principle and Logical Fallacies31:56 Great Barrington Declaration and Scientific Dissent45:37 Public Perception and Media Influence49:51 Introduction to Vaccine Narratives50:12 Public Response and Social Dynamics51:23 Questioning Public Health Directives52:50 Media and Information Control53:32 Discussion on Ivermectin and Vaccines54:35 Exploring Ancient Irish Ethnopharmacology55:08 The Role of Streptomyces in Medicine01:01:35 Mathematical Models and Policy Decisions01:09:12 Seasonality and Stringency of COVID Measures01:16:44 Pharmaceutical Interventions and Controversies01:26:16 WHO's Ivermectin and Remdesivir Analysis01:26:44 Exclusion of Ivermectin Studies01:29:50 HCQ Trials and Data Issues01:32:50 Public Perception and Media Influence01:37:23 Vaccine Technology and Public Awareness01:48:54 Adverse Reactions and Reporting02:02:20 Final Thoughts and RecommendationsRonan's X: https://x.com/1RonanConnollyGerry's X: https://x.com/jercuinnFrom Ronan: The paper (37 co-authors) covers many topics, but this 28 min Alex Newman interview gives a great overview of our key findings: https://x.com/1RonanConnolly/status/1932831388790624445The paper itself: https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2025.1607727/full—AI summaries of all of my podcasts: https://tomn.substack.com/p/podcast-summariesMy Linktree: https://linktr.ee/tomanelson1

Jones Health Law Podcast
EDUCATION: What is the difference between CMS Preclusiona and OIG Exclusion

Jones Health Law Podcast

Play Episode Listen Later Jun 18, 2025 5:53


Web: www.JonesHealthLaw.comPhone: (305)877-5054Instagram: @JonesHealthLawFacebook: @JonesHealthLawYouTube: @JonesHealthLawThe Centers for Medicare & Medicaid Services (CMS) established the Preclusion List under its authority to administer Medicare Advantage (MA) and Part D programs. The list features healthcare providers and prescribers who are precluded from receiving payment for items or services furnished to Medicare beneficiaries enrolled in MA plans or for prescriptions covered under Part D.The U.S. Department of Health and Human Services, Office of Inspector General (OIG) maintains the List of Excluded Individuals and Entities (LEIE) under the authority of the Social Security Act §§ 1128 and 1156. Exclusions are imposed on individuals or entities found to have engaged in certain misconduct, such as fraud or patient abuse.

Cardiology Trials
Review of the CIBIS II Trial

Cardiology Trials

Play Episode Listen Later Jun 17, 2025 5:17


The Lancet Volume 353, Issue 9146 p9-13 January 02, 1999Background: Accumulating data at the time suggested functional benefits of antagonism of beta-adrenoreceptors in patients with heart failure. Multiple specific beta-blockers were being tested in trials. The CIBIS 1 trial found a trend towards 20% lower mortality in the bisoprolol (a highly cardio-selective beta-blocker) group and 30% fewer admissions to hospital for worsening heart failure. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II) trial was designed to test this evidence further.Patients Eligible patients had New York Heart Association Class III-IV symptoms with LVEF ≤ 35% and were stable on diuretics and ACE-inhibitors. Exclusion criteria included recent MI or coronary intervention, AV block or resting heart rate less 60 bpm and systolic BP < 100 mmHg. Patients already on beta-blockers or with planned therapy with beta-blockers were also not enrolled.Cardiology Trial's remains independent, free of industry ads, due to reader generosity. Please consider becoming a free or paid subscriber.Baseline Characteristics The mean age of patients was 61 years, 81% male, and 83% Class III. The mean LVEF was 28%. About half the patients had ischemic heart disease, 12% primary dilated cardiomyopathy and nearly 40% had a mixture of valvular heart disease, hypertensive heart disease or unproven ischemic disease.The mean SBP on enrollment was 130 mmHg and resting HR was 80 bpm. The mean duration of heart failure before enrollment was 3.5 years. About 20% had AF at baseline. Nearly all patients were on ACE-I and half were on digoxin.Trial Procedures There was no run-in period. CIBIS II was double blinded. Slightly more than 2,600 patients were randomized 1:1 to bisoprolol or placebo in 274 hospitals across 18 countries.Patients in the bisoprolol group were started at 1.25 mg daily and titrated up weekly to as high as 10 mg daily. The goal was to attempt the highest tolerated dose. Patients were seen every 3 months.Endpoints The primary endpoint was all-cause mortality. Secondary endpoints included all-cause hospital admissions, cardiovascular mortality, combined CV death and CV hospital admissions, and premature treatment withdrawals.The authors estimated a 11.2% mortality in the placebo group and powered the trial to find a 25% reduction in death in the bisoprolol arm over 2 years.Results The trial was sopped early (mean follow-up 1.3 years) after the planned second interim analysis for benefit. The primary outcome of all-cause death occurred in 11.8% in the bisoprolol group vs 17.3% in the placebo arm (HR 0.66 (95% CI 0.54-0.81, p < 0.0001)).Bisoprolol reduced sudden death (3.6% vs 6.3%), all-cause hospitalization (33% vs 39%), CV death (9% vs 12%). Permanent treatment withdrawal occurred in 15% of both arms.The subgroup analysis showed no substantial treatment heterogeneity. The most common dose was 10 mg daily reached in 43% of patients.Conclusion The 34% reduction in death was clinically meaningful and statistically robust. Our confidence in such a large effect size stems from a) previous data on beta-blockers, which found similar effects, b) the 42% reduction in sudden death in the bisoprolol arm and c) the large reductions in all-cause hospitalization. In addition, the trial conduct appeared strong with almost no lost-to-follow up. The lack of run-in period strengthens the external validity of CIBIS II.The same caveats seen in the US carvedilol trial also apply to CIBIS II, namely that patients were ambulatory, outpatients, mostly with Class III symptoms. Patients enrolled in the trial had a mean SBP of 130 mmHg and a resting heart rate of 80. Nearly all patients were tolerating ACE-I and half were taking digoxin. In addition, patients were started on low-dose and gradually titrated higher. The majority of patients were on higher than 5 mg daily.The authors warned against applying these results to non-ambulatory patients with Class IV symptoms, especially if there was recent instability. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

The Habit
Miroslav Volf on The Cost of Ambition

The Habit

Play Episode Listen Later Jun 16, 2025 45:28 Transcription Available


Miroslav Volf is a theologian and professor at Yale Divinity School, where he is the founding director of the Yale Center for Faith and Culture. He is widely known for his work on reconciliation, forgiveness, and the intersection of faith and public life. He’s the author of at least twelve books, including the highly influential Exclusion and Embrace, as well as many articles and quite a few co-authored books. His most recent book is The Cost of Ambition: How Striving to Be Better than Others Makes Us Worse. In this episode, Dr. Volf and Jonathan Rogers talk about the difference between striving for excellence and striving for superiority. They talk about the freedom to be found when we stop defining ourselves in terms of our status relative to others. Also, they talk a good bit about Satan. This episode is sponsored by The Habit's Short Story Summer Camp, a six-week online writing class devoted to the short story. Find out more at TheHabit.co/ShortStory.Support the show: https://therabbitroom.givingfuel.com/memberSee omnystudio.com/listener for privacy information.

Marceau refait l'info
Exclusion officielle de Nicolas Sarkozy de la légion d'honneur - Hier la fête des pères - 24h du Mans Autos

Marceau refait l'info

Play Episode Listen Later Jun 16, 2025 4:42


On commence avec l'exclusion officielle de Nicolas Sarkozy de la légion d'honneur, paru ce dimanche au Journal Officiel

New Books Network
Ethnic minorities are good for democracy – Here is why

New Books Network

Play Episode Listen Later Jun 12, 2025 35:05


Democracy scholars often assume that ethnic homogeneity is good for democracy. Politically mobilised ethnic minorities, the assumption goes, stoke divisions and can destabilise democracy. In his latest book Ethnic Minorities, Political Competition, and Democracy: Circumstantial Liberals (Oxford UP 2024), Jan Rovny turns this assumption on its head and argues that not only minorities are not bad for democracy but in fact they can help strengthen and protect it. In this episode, he talks with host Licia Cianetti about why this is the case, under what circumstances, and how the book's lessons from minorities in Central and Eastern Europe can travel well beyond the region and might even provide insights to interpret recent voting patterns in the US. Jan Rovny is Professor of Political Science at the Center for European Studies and Comparative Politics at Sciences Po, Paris. Licia Cianetti is Lecturer in Political Science and International Studies at the University of Birmingham and Deputy Founding Director of CEDAR. Her book on these themes is The Quality of Divided Democracies: Minority Inclusion, Exclusion and Representation in the New Europe (University of Michigan Press, 2019). The People, Power, Politics podcast brings you the latest insights into the factors that are shaping and re-shaping our political world. It is brought to you by the Centre for Elections, Democracy, Accountability and Representation (CEDAR) based at the University of Birmingham, United Kingdom. Join us to better understand the factors that promote and undermine democratic government around the world. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

New Books in Political Science
Ethnic minorities are good for democracy – Here is why

New Books in Political Science

Play Episode Listen Later Jun 12, 2025 35:05


Democracy scholars often assume that ethnic homogeneity is good for democracy. Politically mobilised ethnic minorities, the assumption goes, stoke divisions and can destabilise democracy. In his latest book Ethnic Minorities, Political Competition, and Democracy: Circumstantial Liberals (Oxford UP 2024), Jan Rovny turns this assumption on its head and argues that not only minorities are not bad for democracy but in fact they can help strengthen and protect it. In this episode, he talks with host Licia Cianetti about why this is the case, under what circumstances, and how the book's lessons from minorities in Central and Eastern Europe can travel well beyond the region and might even provide insights to interpret recent voting patterns in the US. Jan Rovny is Professor of Political Science at the Center for European Studies and Comparative Politics at Sciences Po, Paris. Licia Cianetti is Lecturer in Political Science and International Studies at the University of Birmingham and Deputy Founding Director of CEDAR. Her book on these themes is The Quality of Divided Democracies: Minority Inclusion, Exclusion and Representation in the New Europe (University of Michigan Press, 2019). The People, Power, Politics podcast brings you the latest insights into the factors that are shaping and re-shaping our political world. It is brought to you by the Centre for Elections, Democracy, Accountability and Representation (CEDAR) based at the University of Birmingham, United Kingdom. Join us to better understand the factors that promote and undermine democratic government around the world. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/political-science

Cardiology Trials
Review of the CHARM-Added trial

Cardiology Trials

Play Episode Listen Later Jun 11, 2025 10:32


THE LANCET 2003;362:767-771Background: Angiotensin II which plays a role in ventricular remodeling and progression of heart failure can be produced by pathways independent of angiotensin convening enzyme. Preliminary studies showed that the combination of angiotensin II blockers with angiotensin-converting enzyme inhibitors (ACEi) improves hemodynamics and reduces ventricular remodeling.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.The Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM)-Added trial sough to assess if adding the angiotensin-receptor blocker (ARB), candesartan, to ACEi could improve outcomes in patients with systolic heart failure.Patients: Eligible patients had left ventricular ejection fraction of 40% or less within the previous 6 months, and NYHA class II, III or IV symptoms. Patients with NYHA class II symptoms had to have cardiac-related hospitalization within 6 months. Patients also had to have treatment with ACEi at a constant dose for at least 30 days.Exclusion criteria were not provided in the main manuscript.Baseline characteristics: Patients were recruited from 618 centers in 26 countries. The trial randomized 2,548 patients – 1,276 randomized to receive candesartan and 1,272 to receive placebo.The average age of patients was 64 years and 79% were men. The average left ventricular ejection fraction was 28%. Cardiomyopathy was ischemic in 62% of the patients. The NYHA class was II in 24% of the patients, III in 73% and IV in 3%.Approximately 48% had hypertension, 30% had diabetes, 56% had prior myocardial infarction, 9% had stroke, 27% had atrial fibrillation and 17% were current smokers.At the time of enrollment, 90% were taking a diuretic, 58% were taking digoxin, 55% were taking beta-blockers, 17% were taking spironolactone and all but two patients were taking ACEi.Procedures: The trial was double-blinded. Patients were assigned in a 1:1 ratio to receive candesartan starting at 4 or 8mg once daily or placebo. The treatment was doubled every two weeks to a target dose of 32mg once daily.After randomization, follow up occurred at 2, 4, and 6 weeks, 6 months and every 4 months thereafter.Endpoints: The primary outcome was a composite of cardiovascular death or heart failure hospitalizations. All deaths were classified as cardiovascular unless there was a clear non-cardiac cause.Analysis was performed based on the intention-to-treat principle. The estimated sample size to have 80% power at 5% alpha was 2,300 patients. The sample size calculation assumed 16% relative risk reduction in the primary outcome with candesartan assuming an 18% annual event rate in the placebo arm.Results: The median follow up time was 41 months. The mean candesartan daily dose was 24mg at 6 months.Candesartan reduced the primary endpoint of cardiovascular death or heart failure hospitalizations (37.9% vs 42.3%, adjusted HR: 0.85, 95% CI: 0.75 – 0.96; p= 0.01). Candesartan reduced the individual components of the primary outcome - (23.7% vs 27.3%; p= 0.021) for cardiovascular death and (24.2% vs 28.0%; p= 0.018) for heart failure hospitalizations. There was no significant reduction in all-cause death (29.5% with candesartan vs 32.4%; p= 0.105). The number of patients who had any hospitalization was similar in both groups (66.8% with candesartan vs 67.5%; p= 0.7), however, the total number of hospitalizations was lower with candesartan (2,462 vs 2,798; p= 0.023).Serum creatinine at least doubled in 7% of the patients in the candesartan group vs 6% in the placebo group. In the subset of patients taking spironolactone, serum creatinine at least double in 11% of the patients taking candesartan compared to 4% of the patients taking placebo.Hyperkalemia, defined as serum potassium of 6 mmol/L or higher, occurred in 3% of the patients in the candesartan group vs 1% in the placebo group. In the subset of patients taking spironolactone, hyperkalemia occurred in 4% of the patients taking candesartan compared to 1% of the patients taking placebo.There were two cases of angioedema in the candesartan group and three in the placebo group. All patients were taking an ACEi.There were no significant subgroup interactions, including in patients taking both beta-blockers and ACEi at baseline.Conclusion: In patients with systolic heart failure, adding candesartan to an ACEi reduced the primary composite outcome of cardiovascular death or heart failure hospitalizations with a number needed to treat of approximately of 23 patients over 41 months of follow up. The total number of all-cause hospitalizations was reduced by 336 with candesartan. All-cause death was not significantly reduced with candesartan.While the results of the trial appear impressive, the high number of adverse outcomes with candesartan in patients taking spironolactone is concerning. Spironolactone led to significant reduction in all-cause mortality in patients with systolic heart failure, as seen in the RALES trial, and should be prioritized over adding candesartan. Notably, fewer than 20% of patients in the trial were on spironolactone at baseline; if more had been, the incremental benefit of candesartan would likely have been reduced due to an increased risk of adverse effects from triple neurohormonal blockade (ACEi, ARBs, and mineralocorticoid receptor antagonists). Furthermore, spironolactone acts by blocking the aldosterone receptor, which is downstream in the renin–angiotensin–aldosterone system. Since candesartan blocks angiotensin II upstream in the same pathway, simultaneous inhibition at multiple points may lead to diminishing benefit.Finally, the differences observed in the subgroup of patients on beta-blockers between this trial and Val-HeFT remain unclear and may simply reflect the play of chance. As we previously discussed, patients receiving both an ACEi and beta-blockers had worse outcomes with valsartan in the Val-HeFT trial.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

RNZ: Afternoons with Jesse Mulligan
Book Critic: Pip Adam

RNZ: Afternoons with Jesse Mulligan

Play Episode Listen Later Jun 10, 2025 9:04


Pip reviews Prairie, Dresses, Art, Other by Danielle Dutton (Coffee House Press), American Precariat: Parable of Exclusion by Zeke Caligiuri (Coffee House Press) and Sound Museum by Poupeh Massaghi (Coffee House Press).

Tent Talk
Ep 348: Sagdrina Brown Jalal | Building A Bigger Tent: Rooted in Resilience

Tent Talk

Play Episode Listen Later Jun 9, 2025 42:10


We're talking this month about Building a Bigger Tent at our farmers markets. Let's remember that the more people and communities we welcome to markets, the deeper our variety of produce, products and personalities. Exclusion, whether purposeful or just thoughtless, means we miss out on all the richness that comes with diversity.   Sagdrina Brown Jalal is back with us for this episode, just in time for Juneteenth. While that day of historic remembrance is coming up next week on June 19th, observances and events will start this weekend and extend into next. We're talking about how your market can support that holiday. And we're looking at how organizations like the West Georgia Farmers Cooperative are working to level the playing field and lift up small farmers all year round. Tune in while we discuss:   Support can be more appropriate than leadership The exhausting history of resilience Bridging urban and rural division Looking beyond Federal funding Partnership and collaboration as strength #Farmersmarkets #Juneteenth #Blackfarmersmarkets #Cooperatives #Belovedcommunity #SageDCollective

Smart Social Podcast: Learn how to shine online with Josh Ochs
The Quiet Hurt of Online Exclusion: Helping Kids Navigate Digital Rejection

Smart Social Podcast: Learn how to shine online with Josh Ochs

Play Episode Listen Later Jun 6, 2025 2:37


Join our next weekly live parent events:  https://smartsocial.com/eventsWhat does online exclusion really feel like for kids—and how can parents and educators help?In this Josh Talk, we explore the emotional impact of being left out online. Whether it's being ghosted in a group chat or seeing a party they weren't invited to, these digital moments can affect a child's self-esteem.Josh shares practical ways to:Recognize when your child is quietly hurtingReframe online rejection and model healthy copingStrengthen offline relationships to build confidenceTune in to learn how to support students through the ups and downs of digital life.Become a Smart Social VIP (Very Informed Parents) Member: https://SmartSocial.com/vipDistrict Leaders: Schedule a free phone consultation to get ideas on how to protect your students in your community https://smartsocial.com/partnerDownload the free Smart Social app: https://www.smartsocial.com/appdownloadLearn about the top 190+ popular teen apps: https://smartsocial.com/app-guide-parents-teachers/View the top parental control software: https://smartsocial.com/parental-control-software/The SmartSocial.com Podcast helps parents and educators to keep their kids safe on social media, so they can Shine Online™

Love Is Stronger Than Fear
The Cost of Ambition with Miroslav Volf, PhD

Love Is Stronger Than Fear

Play Episode Listen Later Jun 3, 2025 50:42 Transcription Available


Ambition is the air we breathe—but what is it costing us? In this episode, Amy Julia Becker and theologian Miroslav Volf discuss his latest book, The Cost of Ambition. They unpack the hidden damage of a culture obsessed with competition and invite us to imagine a new way of being, for ourselves and our society, rooted not in achievement, but in love, mutuality, and genuine abundance. They explore:  Striving for superiority in American cultureThe dark side of competitionLonging for what we haveStriving for excellence vs. striving for superiorityThe illusion of individual achievementPractices for embracing love and generosityReimagining human relationships beyond superiority__MENTIONED IN THIS EPISODE:The Cost of Ambition: How Striving to Be Better Than Others Makes Us Worse by Miroslav VolfAbundance by Ezra KleinThe Sabbath by Abraham HeschelLuke 18:9-14, Philippians 2, 1 Corinthians 12:21-26, Mark 10:35-45The Magnificat (Luke 1:46-55)Works of Love by Søren KierkegaardSubscribe to Amy Julia's newsletter_WATCH this conversation on YouTube by clicking here. READ the full transcript and access detailed show notes by clicking here or visiting amyjuliabecker.com/podcast._ABOUT:Miroslav Volf (DrTheol, University of Tübingen) is the Henry B. Wright Professor of Theology at Yale Divinity School and founding director of the Yale Center for Faith and Culture in New Haven, Connecticut. He has written or edited more than two dozen books, including the New York Times bestseller Life Worth Living, A Public Faith, Public Faith in Action, and Exclusion and Embrace (winner of the Grawemeyer Award in Religion and selected as among the 100 best religious books of the 20th century by Christianity Today). Educated in his native Croatia, the United States, and Germany, Volf regularly lectures around the world. CONNECT with Miroslav Volf on X at @miroslavvolf.Photo Credit: © Christopher Capozziello___Let's stay in touch. Subscribe to my newsletter to receive weekly reflections that challenge assumptions about the good life, proclaim the inherent belovedness of every human being, and envision a world of belonging where everyone matters.We want to hear your thoughts. Send us a text!Connect with me: Instagram Facebook YouTube Website Thanks for listening!

Open||Source||Data
Building Open-Source LLMs with Philosophy | Anastasia Stasenko

Open||Source||Data

Play Episode Listen Later Jun 3, 2025 57:45


Join Charna Parkey as she welcomes Anastasia Stasenko, CEO and co-founder of pleias, through her unique journey from philosophy to building open-source, energy-efficient LLMs. Discover how pleias is revolutionizing the AI landscape by training models exclusively on open data and establishing a precedent for ethical and socially acceptable AI. Learn about the challenges and opportunities in creating multilingual models and contributing back to the open-source community. QUOTES[00:00:00] Introducing Anastasia and pleias[00:02:00] From Philosophy to AI[00:06:00] The Problem of Generic Models[00:10:00] Open Weights vs. Open Source vs. Open Science[00:14:00] Why Open Data Matters[00:18:00] High-Quality, Specialized Models[00:22:00] Multilingual Challenges[00:26:00] Global Inclusion Requires Small Models[00:30:00] Using and Contributing to Wikidata[00:38:00] The Future: Specialized Models[00:48:00] Advice for Newcomers[00:54:00] Cultural Sensitivity and Data Representation[00:50:00] Leo's Takeaways[00:52:00] Charna on Ethical, Verifiable AI[00:54:00] Representation vs. Exclusion[00:56:00] Letting People Be More Human[00:57:30] Applied, Transformative AIQUOTESCharna:"If you didn't make it represented in the data, then we're leaving another culture behind... So which one are you wanting to do, misrepresent them or just completely leave them behind from this technical revolution?"Anastasia:"The real issue now is that the lack of diversity in the current AI labs leads to the situation where all LLMs look alike."Anastasia:"Being able to design, to find, and also to create the appropriate data mix for large language models is something that we shouldn't really forget about when we talk about the success of what large language models are."

The Kevin Sheehan Show
Eric Edholm breaks down Commanders' roster and top 10 rank exclusion

The Kevin Sheehan Show

Play Episode Listen Later Jun 2, 2025 19:01


6.2.25, Eric Edholm from NFL Network joins Denton Day to break down the Commanders roster and what went into his NFL roster ranking list.

The Military Money Manual Podcast
CZTE The Triple Tax Benefits of Combat Zone Tax Exclusion | Tax Free Pay for Military #177

The Military Money Manual Podcast

Play Episode Listen Later Jun 2, 2025 20:01


Did you know there's a way to get tax-free income, tax-free growth, AND tax-free withdrawals—all legally? If you're in the military, you have access to one of the most powerful wealth-building tools that civilians can only dream of. Combat Zone Tax Exclusion (CZTE) is the golden ticket, and in this episode, we break down exactly how you can leverage it to maximize your savings and accelerate your journey to financial freedom. Episode Summary: Military members deployed to a Combat Zone Tax Exclusion (CZTE) location receive tax-free pay, but did you know this can also supercharge your retirement savings?  No federal income tax on military pay earned in a combat zone. Contributions to Roth IRA or Roth TSP using tax-exempt combat pay grow tax-free. Withdrawals in retirement are completely tax-free, giving you a massive financial advantage. We also discuss the Savings Deposit Program (SDP), tips for avoiding common financial mistakes, and strategies to maximize your tax-free earnings while deployed. Key Takeaways: Maximize Your Benefits: Understand the triple tax benefits and how to supercharge your Roth TSP and Roth IRA. Combat Zone Pay Benefits: Know which locations qualify and how even touching a combat zone for one day can get you CZTE benefits. Emergency Fund First: Use the extra tax-free income to build financial security before investing. Savings Deposit Program (SDP): Earn a guaranteed 10% return with this little-known military savings program. Tax Planning Strategies: Advanced moves like Roth conversions, tax-gain harvesting, and earned income tax credit eligibility. Watch Out for Common Mistakes: Avoid lifestyle inflation and missed opportunities to grow tax-free wealth. Links mentioned today: IRS Publication 3, Armed Forces Tax Guide IRS.gov CZTE locations (as of this publishing) DFAS.mil's Imminent Danger Pay (IDP) info Savings Deposit Program (SDP) Article Responding to CP04 IRS Letter Article Military Tax Experts Alliance Episode 167 w/ Ryan Guina, Contributing up to $70,000 to TSP while Deployed! Episode 116 - Roth TSP and Roth IRA are Different!! For a limited time, Spencer is offering one-on-one Military Money Mentor sessions! Get your personal military money and investing questions answered in a confidential coaching call. Our new TSP course is live! Check out the Confident TSP Investing course at militarymoneymanual.com/tsp to learn all about the Thrift Savings Plan and strategies for growing your wealth while in the military. Use promo code "podcast24" for $50 off. Plus, for every course sold, we'll donate one course to an E-4 or below- for FREE! If you have a question you would like us to answer on the podcast, please reach out on instagram.com/militarymoneymanual or email podcast@militarymoneymanual.com. If you want to maximize your military paycheck, check out Spencer's 5 star rated book The Military Money Manual: A Practical Guide to Financial Freedom on Amazon or at shop.militarymoneymanual.com. I also offer a 100% free course on military travel hacking and getting annual fee waived credit cards, like The Platinum Card® from American Express, the American Express® Gold Card, and the Chase Sapphire Reserve® Card in my Ultimate Military Credit Cards Course at militarymoneymanual.com/umc3. Learn how to get your annual fees waived on premium credit cards from American Express in the Ultimate Military Credit Cards Course at militarymoneymanual.com/umc3. The Platinum Card® from American Express and the American Express® Gold Card waive the annual fee for active duty military servicemembers, including Guard and Reserve on active orders over 30 days. The annual fees on all personal Amex cards are also waived for military spouses married to active duty troops.

Two Minutes in Trade
Two Minutes in Trade - USTR Extended Section 301 Duty Exclusion Extended the Expiration Date to August

Two Minutes in Trade

Play Episode Listen Later Jun 2, 2025 3:24


Section 301 tariff exclusions due to expire on 5/31 were extended at the last minute until 8/31. Listen for more on Two Minutes in Trade. 

Good Faith
Michael Luo: Exclusion and Belonging in Immigrant America

Good Faith

Play Episode Listen Later May 29, 2025 31:30


What does it mean to truly belong in America?  Michael Luo, executive editor at The New Yorker and author of Strangers in the Land, joins Redeeming Babel's director of content, DT Slouffman, to explore the Asian American experience—from the legacy of the Chinese Exclusion Act to the rise in anti-Asian hate during the COVID-19 pandemic. Drawing from personal stories and a viral moment that sparked national conversation, Luo confronts the “perpetual foreigner” stereotype and envisions a more inclusive vision of American identity. DT and Michael unpack how race, immigration, and belonging continue to shape all of our lives. Send written questions or voice memos for “Ask Curtis” episodes to: askcurtis@redeemingbabel.org Send Campfire Stories to: info@redeemingbabel.org   Resources mentioned in this episode: Michael Luo's An Open Letter to the Woman Who Told My Family to Go Back to China Kirkus Reviews: A Vast History Began With One Sidewalk Encounter  Chinese Exclusion Act, 1882 The Burlingame-Seward Treaty, 1868 Immigration and Nationality Act, 1965 Pew Research: Asian American discrimination in the COVID-19 pandemic Pew Research: A third of Asian Americans changed daily routine due to threats   More From Michael Luo: Michael Luo's Strangers in the Land: Exclusion, Belonging, and the Epic Story of the Chinese in America  Michael Luo's latest articles at The New Yorker Follow Michael Luo on Instagram Follow Michael Luo on X (formerly Twitter)   Follow Us: Good Faith on Instagram Good Faith on X (formerly Twitter) Good Faith on Facebook   Sign up: Redeeming Babel Newsletter

Key Ministry: the Podcast
148: From Exclusion to Embrace: Creating Churches Where Everyone Belongs with Dr. Erik Carter

Key Ministry: the Podcast

Play Episode Listen Later May 29, 2025 33:25


At the heart of Dr. Erik Carter's Main Stage talk at Disability and the Church Conference 2025, lies a compelling vision: a church where everyone — no asterisks, no exceptions — is welcomed, valued, and needed. His message to ministry leaders and congregations is both a challenge and an encouragement: shift from passive welcome to active inclusion, especially for families impacted by disability.Find the full show-notes at: www.keyministry.org/podcast/

AP Audio Stories
Chinese students call measure 'Chinese Exclusion Act' after Rubio vows to revoke visas

AP Audio Stories

Play Episode Listen Later May 29, 2025 0:46


AP correspondent Charles de Ledesma reports Chinese university students in Beijing are concerned over the future of student exchange programs, after Secretary of State Marco Rubio said some Chinese students would have their U.S. visas revoked.

CCO Medical Specialties Podcast
Conversations in Chronic Cough: An Allergist's Perspective

CCO Medical Specialties Podcast

Play Episode Listen Later May 28, 2025 16:36


Listen as Michael S. Blaiss, MD provides case-based perspectives on chronic cough recognition, burden, management, and pathophysiology and describes the evolving treatment landscape for refractory chronic cough.PresenterMichael S. Blaiss, MDClinical Professor of PediatricsDivision of Allergy-ImmunologyMedical College of Georgia at Augusta UniversityAugusta, GeorgiaLink to full program: https://bit.ly/4kweynG

New Books in Gender Studies
Luanjiao Hu, "Inclusion, Exclusion, Agency, and Advocacy: Experiences of Women With Physical Disabilities in China, With Worldwide Implications" (IAP, 2024)

New Books in Gender Studies

Play Episode Listen Later May 27, 2025 65:22


Inclusion, Exclusion, Agency, and Advocacy: Experiences of Women With Physical Disabilities in China, With Worldwide Implications (IAP, 2024) explores the lived experiences of six women, including the author herself, with physical disabilities in China. The book provides in-depth descriptions of each woman's experiences in different aspects and analyze the commonalities and differences in their experiences through their life courses. The book explores answers to some of these questions: How do physically disabled women make sense of their experiences? What are some of the empowering and/or disempowering moments/events in their lives, if any? What are disabled women's experiences in terms of education, employment, relationships, family life, and social activism? How does some of the disabled women in the book become motivated and mobilized to work on disability issues? This book serves to amplify Chinese disabled women's stories and make their presence more visible. Too often, dominant narratives and depictions of disability are written by people without disabilities, while disabled people's voices are either invisible or secondary. Sadly, this phenomenon is not new and disability advocates have been faced with these types of narratives for quite some years. To have one's own voice and speak up is to claim subjectivity, agency, and power. Different stories told by women with disabilities themselves can enrich our understanding of disability and gender. These stories have the potential to challenge dominant and oppressive narratives prevalent in our ableist societies. The stories included in this book could provide space and potential to connect with disabled people (people with either visible or invisible disabilities) elsewhere. Women's empowering experiences and encounters shown in this book could inspire relevant stakeholders to think of ways to better understand and support disabled women in their environments. This book will have wide implications for readers not only in China, but also in other parts of the world. Many disability stories of exclusion and/or empowerment of the world are still hidden and not reflected upon. The author invites readers to reflect on their own experiences and how societies have impacted the life courses of individuals with or without disabilities in their respective social, political, economic, and cultural environments. Cultural and social change around disability can start with anyone who are touched by genuine stories of vulnerability and reflexivity, as the ones to be shared in this book. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/gender-studies

The Midlife Revolution
LDS Bigotry: Revealing Dallin Oaks' Views on Women, Family, and the Exclusion of LGBTQ Blessings

The Midlife Revolution

Play Episode Listen Later May 26, 2025 45:32 Transcription Available


Dive deep into the complexities of faith, identity, and personal growth in this transformative episode of "The Midlife Revolution." In this episode, I explore my journey of leaving the Mormon Church after decades of membership, focusing on a significant talk by Elder Dallin H. Oaks from October 2019. This discussion centers on his views on women's roles and the church's stance towards the LGBTQ community, highlighting the gap between the church's inclusive rhetoric and its exclusionary policies.Listen as I dissect the implications of these teachings on personal lives, especially for women over 40 who are reevaluating their faith and seeking authenticity in their spiritual journey.Learn how small, positive changes can lead to profound life improvements, using my own experience as a testament to the power of personal revolution at midlife.Explore the dissonance between 'all are welcome' statements and the reality of church policies that bar full participation for the LGBTQ community.This episode is not just about critique; it's a beacon for those navigating their way out of high control environments, whether religious, familial, or otherwise. Join the conversation on:Finding your voice after years of silenceRebuilding your life with authenticity and joy Embracing change in midlife Leaving Mormon Church, high control religions, women over 40, Dallin H. Oaks, LDS Church critique, faith deconstruction, personal growth, midlife change, small positive changes, LGBTQ exclusion, spiritual awakening, authenticity in faith, leaving religion, life after church, women's roles in church. #MidlifeRevolution #FaithDeconstruction #HighControlReligionSubscribe to "The Midlife Revolution" for more stories of transformation, empowerment, and finding your path in midlife. Click the bell icon to get notified about new videos that might just change your life's trajectory. Join our community of brave souls choosing to live their truth, one step at a time.

New Books Network
Luanjiao Hu, "Inclusion, Exclusion, Agency, and Advocacy: Experiences of Women With Physical Disabilities in China, With Worldwide Implications" (IAP, 2024)

New Books Network

Play Episode Listen Later May 25, 2025 65:22


Inclusion, Exclusion, Agency, and Advocacy: Experiences of Women With Physical Disabilities in China, With Worldwide Implications (IAP, 2024) explores the lived experiences of six women, including the author herself, with physical disabilities in China. The book provides in-depth descriptions of each woman's experiences in different aspects and analyze the commonalities and differences in their experiences through their life courses. The book explores answers to some of these questions: How do physically disabled women make sense of their experiences? What are some of the empowering and/or disempowering moments/events in their lives, if any? What are disabled women's experiences in terms of education, employment, relationships, family life, and social activism? How does some of the disabled women in the book become motivated and mobilized to work on disability issues? This book serves to amplify Chinese disabled women's stories and make their presence more visible. Too often, dominant narratives and depictions of disability are written by people without disabilities, while disabled people's voices are either invisible or secondary. Sadly, this phenomenon is not new and disability advocates have been faced with these types of narratives for quite some years. To have one's own voice and speak up is to claim subjectivity, agency, and power. Different stories told by women with disabilities themselves can enrich our understanding of disability and gender. These stories have the potential to challenge dominant and oppressive narratives prevalent in our ableist societies. The stories included in this book could provide space and potential to connect with disabled people (people with either visible or invisible disabilities) elsewhere. Women's empowering experiences and encounters shown in this book could inspire relevant stakeholders to think of ways to better understand and support disabled women in their environments. This book will have wide implications for readers not only in China, but also in other parts of the world. Many disability stories of exclusion and/or empowerment of the world are still hidden and not reflected upon. The author invites readers to reflect on their own experiences and how societies have impacted the life courses of individuals with or without disabilities in their respective social, political, economic, and cultural environments. Cultural and social change around disability can start with anyone who are touched by genuine stories of vulnerability and reflexivity, as the ones to be shared in this book. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

New Books in East Asian Studies
Luanjiao Hu, "Inclusion, Exclusion, Agency, and Advocacy: Experiences of Women With Physical Disabilities in China, With Worldwide Implications" (IAP, 2024)

New Books in East Asian Studies

Play Episode Listen Later May 25, 2025 65:22


Inclusion, Exclusion, Agency, and Advocacy: Experiences of Women With Physical Disabilities in China, With Worldwide Implications (IAP, 2024) explores the lived experiences of six women, including the author herself, with physical disabilities in China. The book provides in-depth descriptions of each woman's experiences in different aspects and analyze the commonalities and differences in their experiences through their life courses. The book explores answers to some of these questions: How do physically disabled women make sense of their experiences? What are some of the empowering and/or disempowering moments/events in their lives, if any? What are disabled women's experiences in terms of education, employment, relationships, family life, and social activism? How does some of the disabled women in the book become motivated and mobilized to work on disability issues? This book serves to amplify Chinese disabled women's stories and make their presence more visible. Too often, dominant narratives and depictions of disability are written by people without disabilities, while disabled people's voices are either invisible or secondary. Sadly, this phenomenon is not new and disability advocates have been faced with these types of narratives for quite some years. To have one's own voice and speak up is to claim subjectivity, agency, and power. Different stories told by women with disabilities themselves can enrich our understanding of disability and gender. These stories have the potential to challenge dominant and oppressive narratives prevalent in our ableist societies. The stories included in this book could provide space and potential to connect with disabled people (people with either visible or invisible disabilities) elsewhere. Women's empowering experiences and encounters shown in this book could inspire relevant stakeholders to think of ways to better understand and support disabled women in their environments. This book will have wide implications for readers not only in China, but also in other parts of the world. Many disability stories of exclusion and/or empowerment of the world are still hidden and not reflected upon. The author invites readers to reflect on their own experiences and how societies have impacted the life courses of individuals with or without disabilities in their respective social, political, economic, and cultural environments. Cultural and social change around disability can start with anyone who are touched by genuine stories of vulnerability and reflexivity, as the ones to be shared in this book. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/east-asian-studies

New Books in Chinese Studies
Luanjiao Hu, "Inclusion, Exclusion, Agency, and Advocacy: Experiences of Women With Physical Disabilities in China, With Worldwide Implications" (IAP, 2024)

New Books in Chinese Studies

Play Episode Listen Later May 25, 2025 65:22


Inclusion, Exclusion, Agency, and Advocacy: Experiences of Women With Physical Disabilities in China, With Worldwide Implications (IAP, 2024) explores the lived experiences of six women, including the author herself, with physical disabilities in China. The book provides in-depth descriptions of each woman's experiences in different aspects and analyze the commonalities and differences in their experiences through their life courses. The book explores answers to some of these questions: How do physically disabled women make sense of their experiences? What are some of the empowering and/or disempowering moments/events in their lives, if any? What are disabled women's experiences in terms of education, employment, relationships, family life, and social activism? How does some of the disabled women in the book become motivated and mobilized to work on disability issues? This book serves to amplify Chinese disabled women's stories and make their presence more visible. Too often, dominant narratives and depictions of disability are written by people without disabilities, while disabled people's voices are either invisible or secondary. Sadly, this phenomenon is not new and disability advocates have been faced with these types of narratives for quite some years. To have one's own voice and speak up is to claim subjectivity, agency, and power. Different stories told by women with disabilities themselves can enrich our understanding of disability and gender. These stories have the potential to challenge dominant and oppressive narratives prevalent in our ableist societies. The stories included in this book could provide space and potential to connect with disabled people (people with either visible or invisible disabilities) elsewhere. Women's empowering experiences and encounters shown in this book could inspire relevant stakeholders to think of ways to better understand and support disabled women in their environments. This book will have wide implications for readers not only in China, but also in other parts of the world. Many disability stories of exclusion and/or empowerment of the world are still hidden and not reflected upon. The author invites readers to reflect on their own experiences and how societies have impacted the life courses of individuals with or without disabilities in their respective social, political, economic, and cultural environments. Cultural and social change around disability can start with anyone who are touched by genuine stories of vulnerability and reflexivity, as the ones to be shared in this book. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/chinese-studies

The Hidden Addiction Podcast
The Hidden Addiction Podcast - Voluntary Self-Exclusion

The Hidden Addiction Podcast

Play Episode Listen Later May 22, 2025 17:25


In this episode we welcome Sarah Bryant, Finger Lakes Program Manager, and Isabel Barbosa, Special Population Coordinator. They join us to discuss the Voluntary Self-Exclusion program and supportive services. Questions that are discussed include:What is Voluntary Self-Exclusion (VSE)?What is the process to complete the VSE form?How can we connect with help to complete the VSE form?How does the VSE program work with casinos and benefit them?How does the VSE help make the casino environment better?How is an empathetic approach a beneficial strategy?Is there something we're doing with the casinos that can help them?Do we have a training that is specific to casino employees?Can someone refer themselves or someone else for VSE?Who do you contact to access this information and support? If you find yourself struggling with gambling harm, or if you suspect someone you know is facing such challenges, don't hesitate to seek help. For 24/7 support, call the NYS OASAS HOPEline at 1-877-846-7369 or text 467369. Or choose your county using our interactive map on our NYProblemGamblingHELP.org HOME PAGE to see the contact information for the Problem Gambling Resource Center (PGRC) in your region.

Youth Culture Today with Walt Mueller
When they are Left Out

Youth Culture Today with Walt Mueller

Play Episode Listen Later May 20, 2025 1:00


Most of us can remember those pit-in-the-stomach times we experienced as teenagers when we realized we had been left out. I remember a summer day in the neighborhood when I couldn't find any of my friends at home. I couldn't figure out why they were all gone until somebody spilled the beans later, telling me that they had all been invited to go to a home in another neighborhood to swim in the families' pool. Truth be told, I felt like a loser. The journal Frontiers in Digital Health reports that for kids living in today's social media world, the feelings I felt on that one summer day occur far more frequently, as our kids see visual and story content recounting activities and gatherings of friends from which they've been excluded. This ramps up feelings of exclusion, jealousy, and rejection. Researchers say this is feeding emotional stress and creating interpersonal conflict. Let's use these moments to teach our kids to handle disappointment and conflict with the kindness and grace of Jesus Christ. 

Holistic Alpha: Male Optimization
Accelerate Your Growth Through Inclusion, Not Exclusion

Holistic Alpha: Male Optimization

Play Episode Listen Later May 19, 2025 7:16


If you're going to grow you need to get rid of those negative habits, negative beliefs, etc—right?? NOPE. Do this instead and you'll grow much faster.

Cardiology Trials
Review of the U.S. Carvedilol Heart Failure Study

Cardiology Trials

Play Episode Listen Later May 14, 2025 8:45


N Engl J Med 1996;334:1349-1355Background Before 1990, the prevailing idea held that the negative inotropy of beta-blockers would harm patients with impaired systolic function. Yet part of the progression of systolic heart failure involved over stimulation of the sympathetic nervous system. Norepinephrine can exert adverse effects on the circulation, both directly and indirectly. Smaller trials of beta-blockers in systolic heart failure found trends for benefit with beta-blockers, however, a mortality benefit had not yet been proven. The U.S. Carvedilol Heart Failure Study aimed to study mortality in patients with heart failure with a reduced ejection fraction.Cardiology Trial's Substack remains free of industry ads because of your support. Thank you. Please consider becoming a free or paid subscriber.Patients The study enrolled 1094 patients with chronic heart failure symptoms for at least 3 months, LVEF ≤ 0.35%, at least 2 months of treatment with diuretics and an angiotensin-converting enzyme (ACE) inhibitor (if tolerated). Treatment with digoxin, hydralazine, or nitrates was permitted but not required.Exclusion criteria were extensive and important to understand. These included any recent major cardiac events or surgery within the previous 3 months, uncorrected valvular disease, active myocarditis, sustained VT or higher degrees of AV block not controlled by pacing, systolic blood pressure of more than 160 or less than 85 mm Hg or diastolic blood pressure of more than 100 mm Hg, clinically significant kidney or liver disease or use of calcium-channel blockers, adrenergic agonists/antagonists, or class IC/III antiarrhythmic agents. Patients receiving β-adrenergic agonists or antagonists (presumably for another indication) were not enrolled.Baseline Characteristics The results of this and other beta-blocker trials in heart failure will be clear. One of the most important points for translating this evidence to patients will be the baseline characteristics. It is vital to understand who these patients were.The mean age was 58 years and approximately 76% were male. Most patients had mild to moderate heart failure, with 53% in NYHA Class II, 44% in Class III, and only 3% in Class IV. The etiology of heart failure was nearly evenly split between coronary artery disease (47%) and nonischemic cardiomyopathy (53%). Patients had significantly impaired cardiac function with a mean LVEF of 0.23. The mean six-minute walk distance ranged from 386 to 390 meters. Hemodynamic parameters were relatively stable, with mean systolic blood pressure of 116 mmHg, and mean heart rate of 83-84 beats per minute. Most patients were receiving standard heart failure therapy at baseline, including digitalis (90-91%), loop diuretics (95%), and ACE inhibitors (95%), while approximately one-third (32%) were on direct-acting vasodilators.Trial Procedures Patients were assessed for eligibility during a 3-week screening period during which exercise capacity was assessed with a 6-minute walk test. Notable was that these were outpatients able to complete a 6-minute walk test. Enrollment was stratified to one of four treatment protocols on the basis of the patients' performance on the exercise test: patients able to walk between 426 and 550 m when tested were assigned to the mild-heart-failure protocol; those able to walk between 150 and 425 m were assigned either to the moderate-heart-failure protocol or to a dose-ranging protocol, depending on the location of the study center; and those able to walk only less than 150 m were assigned to the severe-heart-failure protocol.After this base-line testing, all patients received 6.25mg of carvedilol twice daily for two weeks in an open-label run-in period. Those who tolerated this initial dose were then randomized to receive either placebo (n=398) or carvedilol (n=696) on a double-blind basis, in addition to their usual medications.The allocation ratio (carvedilol:placebo) was 2:1 in the mild and severe heart failure protocols and 1:1 in the moderate heart failure protocol. The dose was gradually increased to target levels of 25-50mg twice daily over 2-10 weeks, followed by maintenance therapy for an additional 6 months (12 months for mild heart failure).Endpoints At the time of trial planning, the original intent was safety. That is, to show that carvedilol did not increase mortality. The original intent was to enroll 1100 patients. As smaller trials on beta-blockers were published, the statistical plan included the possibility of beta-blocker benefit. The trialists therefore planned two sided statistical analysis.Cumulative survival curves were constructed as time-to-first-event plots by Kaplan–Meier survivorship methods and differences between the curves were tested for significance by the log-rank statistic with use of a Cox proportional-hazards regression model (which included the protocol as a covariate).Results Median follow-up was only 6.5 months due to early termination for benefit. The patients mean total daily dose of carvedilol was 45±27 mg. Overall mortality was 7.8% in the placebo group vs. 3.2% in carvedilol group. The relative risk reduction from carvedilol vs placebo was 65% (95% CI, 39-80%; p

All Things to All People with Michael Burns
S7E213 - The Gospel of Exclusion

All Things to All People with Michael Burns

Play Episode Listen Later May 12, 2025 61:54


The Eikon team explores the differences between bounded and centered gospels, discussing the implications of church dynamics on inclusion and exclusion. They delve into the nature of bounded churches, the judgmentalism that can arise, and the importance of fostering a community that encourages exploration of faith. The discussion highlights the spectrum of church mentalities, the impact of exclusion on individual identity, and the need for a more inclusive approach that focuses on unity rather than uniformity.   00:00 Introduction to Bounded and Centered Set Gospels09:13 Exploring the Concept of Bounded vs. Centered Gospels19:09 Real-World Applications and Implications of Gospel Types29:15 Navigating Boundaries in Faith Communities31:42 Understanding Bounded vs. Centered Gospels36:47 The Nature of Bounded Churches40:33 The Role of Judgmentalism in Bounded Groups45:06 Exploring Inclusion and Exclusion48:33 Unity vs. Uniformity in Church Dynamics52:35 The Spectrum of Church Mentalities57:05 The Impact of Exclusion on Individual Identity01:01:39 Navigating Personal Beliefs in Church Contexts01:08:35 Looking Ahead: Centered Gospels

Breaking Free: A Modern Divorce Podcast
8 Telltale Signs You're A Target Of Workplace Bullying Abuse with Rebecca Zung on Negotiate Your Best Life #685

Breaking Free: A Modern Divorce Podcast

Play Episode Listen Later May 7, 2025 101:22