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What if the reason you’re not healing isn’t that you need another diagnosis? 0:08 It’s that your cells aren’t receiving the right signals. Because the body doesn’t run on diagnosis, it runs on 0:16 communication. And peptides are one of the most powerful, most misunderstood 0:21 tools we have for cellular signaling, immune balance, tissue repair, gut 0:27 lining support, metabolic control, brain signaling, sleep cycles, and even sexual 0:35 wellness. Today, I’m going to do what most people won’t. Define peptides in 0:41 plain English for you. break them into categories by what they’re best at and 0:47 tell you which ones are FDA approved on the list and which ones are commonly 0:53 used off label or investigational with the evidence that actually says these 1:00 work. This is going to be a powerful episode and if you’ve ever felt like you’re hearing hype without clarity, 1:07 this one’s for you. So, as usual, grab your cup of coffee or tea and settle in 1:13 as we talk about peptides that can fit into your healing journey. We’re going 1:19 to have a short word from our sponsor. You know, we got to do that. That’s how we stay on the air here. So, we will be 1:26 right back after this. Did you know sweating can literally heal your cells? 1:32I nfrared saunas don’t just relax you. They detox your body, balance hormones, 1:37 and boost mitochondrial energy. I’m obsessed with my health tech sauna. And 1:42 right now, you can save $500 with my code at healthtechalth.com/drmuthqen25. 1:54 All right, here we go, guys. I am excited to dive into peptides with you. 2:00 So understanding peptides is foundational, right? And I’ve been 2:06 studying peptides now for about nine years. Um, and I find that they are 2:13 incredible. Um, so I want to break down for you what peptides actually are, what 2:19 they do, and some of the top peptides that are available today, and how they 2:25 can be utilized. Because I think it’s really important. And I think it’s it’s there’s a lot of confusion out there about what these things actually are and 2:32 are they safe? Are they not? When do we use them? What’s the science behind them? So, we’re going to dive in and 2:38 we’re going to talk about all things peptides. So, let’s get ready here. Here we go. So, peptides are short chains of 2:45 amino acids and they typically range anywhere from 2 to 50 amino acids and 2:51 they’re linked by peptide bonds. So think of them as the superglue that holds the amino acids together. They sit 2:58 between the amino acids and they are full proteins in terms of their size and 3:04 their complex structure. And what makes peptides particularly interesting in 3:10 medicine is their role as signaling molecules. They’re essentially the 3:15 body’s text messages carrying specific instructions to cells and tissues. And 3:21 unlike our proteins which often serve as structural roles or act as enzymes, 3:28 peptides typically function as hormones, neurotransmitters and growth factors and 3:33 they bind to specific receptors on the cell’s surfaces or within the cells and 3:39 they trigger this effect. It’s like a cascade effect of a biochemical reaction 3:45 that ultimately changes the cellular behavior. So basically, it’s changing 3:50 the way the body’s cell structure acts. And this is why peptides can be so 3:56 incredibly powerful and therapeutic when you introduce the right peptide signal. 4:02 Now, you could theoretically redirect cellular processes toward healing, 4:07 towards metabolism, immune balance, tissue repair. Any of those things can 4:14 be manipulated to do a certain thing once we add the peptide. The challenge 4:19 in peptide medicine though lies in distinguishing between those peptides that have been rigorously studied, 4:26 proven safe and effective and approved by regulatory bodies like the FDA versus 4:31 those that exist in what we call the gray zone of a promising clinical data. 4:36 But they really lack human validation so far. And this distinction is critical because the presence of a plausible 4:43 mechanism does not guarantee safety or efficacy in living humans. So, this is 4:50 really important and we’re going to dive in and look at some of the research on all of these different peptides that are 4:56 available and I’m excited to say there’s some amazing peptides being studied right now that unfortunately are not 5:01 available. But I can’t wait to see them hit the market for us because it is going to be a gamecher as far as health 5:09 and longevity. So there is a quality control issue and there is a hidden 5:14 variable in peptide medicine with this and it’s one of the most underappreciated aspects of peptide 5:21 therapy particularly for non-FDA approved peptides. It’s quality control. 5:26 When we discuss pharmaceutical medicines, we take for granted that the pill contains what the label says. Not 5:32 always true depending on where it comes from. You guys, if you’ve heard my episodes before talk about how many of our medications are made in China and 5:41 have been contaminated with other things, you will realize that that is not always true. So, just because it has 5:48 the FDA stamp of approval on the medication, it still does not necessarily mean it’s safe and we still 5:54 need to do our homework on it. So, sorry for digressing on you guys, but you know, when we get a medication, we we 6:00 think that what the amount says is what is there, doesn’t have contaminants, it’s manufactured with good 6:06 manufacturing practices. You’ll see that listed as GMP on the bottle, and it’s been stored properly, it’s been 6:12 maintained stable, and with research peptides and compounded formulations, 6:17 none of this can be assumed. So, I will share a story with you. There was a gentleman that was purchasing these 6:24 peptides online from a research facility and um did not know that they were 6:30 coming from China and he was ordering a particular growth hormone peptide and 6:35 after a little while he had he had done fine for the few first few bottles. After a little while he started having 6:42 some complications. He started getting really irritable and angry and ragy and 6:47 he didn’t quite know what was going on. And so he decided to go get some testing done. He had some blood testing done and 6:53 his testosterone level was over 5,000. So for those of you who know what testosterone level should be for a guy, 7:00 they really shouldn’t be any higher than about 1,00200 would be absolute max that we’d want to see. Now he was taking 7:06 testosterone but not to that degree. And prior to adding this peptide, his 7:12 testosterone was very stable. What they ended up finding out was the peptide that he was getting, whoever was 7:18 manufacturing it added testosterone to the peptide. They felt like if if it had growth hormone, that was great, but if 7:25 it had growth hormone and tes testosterone, all the better. And he didn’t know that. And this is the 7:31 problem that we can have with peptides if you don’t source them properly. if you’re not working with somebody that 7:37 knows how to source them and can prove that they are what they say they are. Um, I’m sure there’s a whole bunch of 7:42 studies out there too of people getting these peptides and paying hundreds of thousands of dollars for them over their 7:48 lifetime and finding out they were nothing more than just sterile water. So, you really do need to be careful 7:53 with your quality control. Now, this kind of leads us right into the next topic that we’re going to talk about and that’s the manufacturing question, 8:00 right? The FDA approved peptides are manufactured in facilities subject to 8:05 the FDA inspection rules following our GMP regulations and these facilities 8:11 must validate their manufacturing process, demonstrate consistency batch to batch, test for purity and potency. 8:18 They need to test for bacterial endotoxins and sterility and they need to maintain detailed records. So, when a 8:25 pharmaceutical company submits a drug application, the FDA inspects the manufacturing facility as part of the 8:32 approval process. If you’re getting peptides from a different country, none of that is happening. And there are some 8:38 ways for us to determine if that is what you’re getting. Typically, the rule of thumb is if your peptides are coming 8:44 with a different colored top, every one of them has a different colored top. Those are typically being sourced out of 8:49 China. I wouldn’t say that’s 100% but that’s kind of the rule of thumb that people follow. So compoundingies these 8:56 are thearmacies that make our bio identical hormones. They can make medications in any dose or strength or 9:02 route. There are thousands of them in every not that not in every state but 9:08 there are thousands of them around the country right now. So these compoundingies are registered as 503A 9:15 facilities. They do traditional compounding for individual prescriptions, right? Like they can make 9:20 thyroid, they can make LDN, they can make estrogen. You can also have a 503b 9:27 facility, which is an outsourcing facility. And these companies produce larger batches of products. They’re they 9:34 have some oversight, but they’re less stringent than for FDA approved 9:40 manufacturers. And state boards of pharmacy regulate a 503A pharmacy. And 9:45 the FDA can inspect the 503b facility, but doesn’t preapprove any of their 9:52 compounding products. So, they can inspect it, but they don’t approve them. So, research chemicals and these 9:58 suppliers operate essentially with no oversight. They explicitly market products for research use only, not for 10:06 human consumption to avoid FDA regulation. If they put that on their 10:12 product, they don’t have to comply to what the FDA is saying. And there is no required manufacturing strategies or 10:19 standards, no required testing, no required sterility assurance, and no enforcement mechanisms if products are 10:26 mislabeled or contaminated. So basically, they don’t have the liability, but that doesn’t mean that 10:31 all of them are badies or bad suppliers. It just means they don’t have to comply 10:37 to the FDA rules. Now, there are many of these companies that I’ve seen and I’ve talked to that do do a lot of this. They 10:44 do test their product for sterility. They do test their product to make sure it is what it says it is. They don’t 10:51 have to, but they do. So, if you’re going to decide to use a company that 10:56 has research only, not for human consumption, at least ask for their 11:02 proof of testing so that you know that the product you’re getting is what it says it is and that it’s clean. Because 11:08 this is where we run into the problem is in purity. So in purity peptide 11:13 synthesis can produce not just the targeted peptide but also related 11:19 peptides with deletions, substitutions, truncations or truncations of amino 11:25 acids. Sorry. And this high performance liquid we call it uh chromatography can 11:30 separate these related impurities and quality and quantify the actual target 11:35 of the peptide content. So a certificate of analysis is what you want to ask these companies for. This shows the HPLC 11:44 the testing mechanism with greater than 95% or ideally 98% purity which 11:51 indicates a higher quality product. So this certificate of analysis can be fabricated may not represent the 11:57 specific batch being sold. It happens. We need to know not everybody is honest. Not everybody, you know, does what they 12:03 say and it does what’s right. But at least you at least they’re giving you something and you have some security. 12:10 and then choose a company that was referred to by someone else that has done some homework as well. In in 12:16 commercial research, there’s independent testing and they research peptides and this has been really shocking 12:23 variability that they’ve seen. Some products contain 50% or less of the 12:29 claimed peptide and some contained primarily degradation of the product or manufacturing impurities and some 12:36 contained bacterial endotoxins at levels that could cause fever and systemic 12:42 inflammation if it was truly injected. And I would also worry with some of those problems, you know, depending on 12:48 what impurity or bacterial endotoxin was there. If you’re using a product to boost your immune system and your immune 12:54 system is already compromised, these bacterial endotoxins can actually make you sicker instead of what you want it 13:02 to do, which is making you better. So, sterility is always an issue with anything that is manufactured, 13:08 especially things that we’re doing as an injection. Peptides are intended for injection. They must be sterile. They 13:16 must be kept safe. And pharmaceutical manufacturers conduct this sterility testing on every batch. 13:22 Compoundingarmacies should conduct sterility testing particularly for high-risisk compounded 13:28 sterile preparations and research chemical suppliers may or may not conduct any testing. So injecting 13:35 non-sterile material can cause local infections, abscesses at the injection 13:41 site and or if the bacteria enters the bloodstream could potentially be 13:46 life-threatening and you could have sepsis. Now, excuse me. We saw this 13:52 happen in a compounding pharmacy uh gosh, it’s probably been 10 years ago 13:57 now, I think. um they unfortunately had a strep uh contamination in their 14:03 product and they weren’t testing it. It was a large compounding pharmacy out of Florida and they were making products 14:08 that were being injected into the joints and um these people got very very sick 14:14 and some of them died and um some of them got very very injured by this uh 14:21 complication that happened. So it’s not like this doesn’t happen. It does, but it doesn’t happen often. And that’s what 14:28 we have to know about. And so, when we’re talking with you guys about storage and stability, it’s really 14:34 important to make sure you maintain your peptides well. So, many peptides are unstable at room temperature. They 14:41 require refrigeration or freezing. We tell everyone to make sure you’re refrigerating your peptides. That way, 14:48 there’s no question about it. when it stays cold um it prevents or slows down 14:54 the process of uh bacteria growing in it. So some of these peptides actually 14:59 degrade very rapidly in the solution and they must be reconstituted immediately before use and reconstitution of the 15:07 peptides really has limited stability often just days to weeks not months. So 15:13 improper storage, temperature, um changes during shipping or prolonged 15:19 storage of a reconstituted product can lead to degradation into inactivity or 15:25 potentially even a harmful breakdown of the product itself. So if you have a product that’s been sitting in your 15:30 refrigerator for a month or two months or 3 months or 6 months, just throw it away. It’s not going to be any good. 15:37 you’re not going to actually get the peptide and the uh potency that you’re looking for anyway out of it and the 15:44 potential of you introducing an endotoxin, a bacterial endotoxin is quite high at that point. So you just 15:50 really don’t want to take the risk, excuse me. So what practitioners, what 15:56 should we do and what should patients do? Well, for any peptide therapy, we 16:03 want to source our verification. know where the peptide product comes from. Is 16:08 it an FDA approved product? Is it a 503b compounding? A research chemical 16:14 supplier? Is there a certificate of analysis? Request and review this COA. 16:20 And you want it to show purity greater than 95% but ideally greater than 98%. 16:27 You want that identity be identity to be confirmed by mass spectromedy. Uh 16:33 sterility testing should be done. Bacterial endotoxin testing should be done. Batch number matching of the 16:39 product that you received should be done. Proper storage. You want to know that this has been refrigerated or 16:46 frozen as directed once it’s been mixed. Look at the expiration dates for reconstituting your peptides. Track that 16:53 reconstitution date and discarded accordingly like we just talked about. Monitor for your adverse effects. Even 17:01 with the perfect quality control, monitoring for adverse effects is essential with questionable quality and 17:08 vigilance is really critical here. I know it’s frustrating for a lot of patients when they have to get several 17:15 bottles and they only last a week or two. right here, you guys. This is why 17:21 they only last a short period of time because once they’re mixed, they start 17:26 to degrade and they won’t be good and you won’t get the benefit from it. So, 17:31 it’s really important with these research peptides specifically, practitioners should recognize that all 17:38 recommending products without quality assurance violates the fundamental medical principle of first do no harm. 17:45 If a patient is determined to use research peptides despite counseling, providing guidance on quality 17:52 verification, requesting those COAs, using pharmaceutical grade sources when available, proper testing, this all 17:59 reduces harm, but doesn’t constitute necessarily that recommendation. Now, 18:06 that being said, today it’s very difficult to find peptides by the compoundingies because of what the FDA 18:13 has done. So most of the peptides that are available to us have been labeled 18:18 not for human consumption, not because they’re not good products, but because 18:25 of what the FDA did. And this is how these companies have been able to 18:31 continue to provide peptides to the medical community. And if you know you 18:36 have a good company, then you’re, you know, you’re still taking the risk, right? But at the end of the day, the 18:42 reason they’re doing that is to protect themselves from the FDA, from liability. Um, so just kind of know that there is 18:50 some talk in the community with um Bobby Kennedy that this is going to change and 18:55 they are going to bring peptides back to the compounding pharmacies. Now, we don’t know which ones they’re going to 19:01 bring back. Uh, will it be all of them? Will it just be some of them? What’s going to happen here? Um, is it going to 19:07 go to the pharmaceutical companies like our GLP1s did? We don’t know what that’s going to look like quite yet. Um, but it 19:14 is coming and that is positive news. So, let’s talk now about FDA approved 19:21 peptide medications. So, this is the metabolic revolution, right? GLP1 19:28 and our dual increeting agonists. This is an exciting time. GLP-1s are amazing. 19:35 Um, a lot of people are skeptical, a lot of people love them, a lot of people hate them. Whichever side of the fence 19:42 that you’re on, I understand. But I want to talk about the science of it today 19:48 and what it actually means for people. So, the story of GLP1 glucagon like 19:54 peptide one represents one of the most significant advances in metabolic 19:59 medicine in the past several decades. GLP-1 is an accretin hormone. It’s 20:05 gutder derived peptide that potentiates insulin secretion in response to food 20:11 intake. And the body naturally produces GLP-1 in the intestinal L cells, but it 20:17 rapidly degraded by the enzyme DPP4 giving it a halflife of only about 2 20:24 minutes. So this rapid breakdown made in therapeutically impractical until 20:31 research was developed and modified the analoges that resist the enzyme degradation. So for those people who 20:39 never feel full when they’re eating, never feel satisfied when they’re done, this is because their body is either not 20:46 producing enough GLP1 or it’s not getting the signal right. And this is a 20:51 leptin issue. This is an insulin issue. It’s a GLP-1 issue. It’s a complicated 20:56 issue. This is not anything that the person is doing wrong. It’s what is happening to their body. And so GLP1s 21:03 have really revolutionized this. So one particular GLP-1 that we have is 21:09 semiglutide. And this GLP-1 agonist is what changed everything in the world of 21:16 metabolic medicine. Semiglutide is marketed as ompic for type 2 diabetes 21:23 and it’s marketed as WGOI for chronic weight management. It is a modified 21:29 GLP-1 analog with 95 or sorry 94% amino acid sequence uh homology to human 21:37 GLP-1. So it means that it’s it’s just like our own GLP-1 that we make. This 21:42 modification includes specific amino acid substitutions and the addition of C18 21:50 a fatty acid chain which allows the peptide to bind to albumin. Now this 21:56 albumin binding dramatically extends the half-life to approximately one week 22:01 enabling one weekly dosing which is a major advantage over the earlier GLP-1 22:07 agonists that require daily or twice daily injections. The mechanism by which 22:13 semiglutide works is multiaceted. At the pancreatin level, it binds to GLP-1 22:20 receptors on the pancreatic beta cells enhancing glucose depending sorry 22:27 enhancing glucose dependent insulin secretion. This glucose dependency is 22:33 crucial. It means the peptide only stimulates insulin release when blood glucose is elevated. This dramatically 22:41 reduces the hypoglycemic risk compared to insulin or even uh sulfuras. 22:47 Simultaneously semiglutide suppresses glucagon secretion from pancreatic alpha 22:53 cells further improving glycemic control. This is really amazing because 23:00 over the years when we’ve used insulin, which is also a peptide by the way, you 23:05 had to dose it just right because if you didn’t, you would produce so much insulin that it would crash the blood 23:12 sugar and then somebody would have too low of a blood sugar. They’d be hypoglycemic and they’d have to eat more 23:18 sugar and then they’d have to modify the insulin again and the person would be going up and down, up and down, up and 23:24 down all day long. And that created a lot of problems for people and so this 23:30 helps to stabilize that so it is not such an intense change. Now in the GI 23:36 tract semiglutide delays the gastric emptying particularly pronounced during 23:41 the initial weeks of therapy. This slowing of the gastric emptying contributes to the sensation of being 23:48 full and early satiety that patients often describe. However, this effect 23:54 tends to attend to weight over time as the body adapts through the appetite 24:00 suppressing effects generally persist through central mechanisms. So, when we 24:05 talk about what is actually happening, we’re slowing that digestive process down. That’s why people aren’t so 24:11 hungry. It’s why they’re not eating so much. This is why people can develop constipation with these products because 24:17 it’s slowing the body’s digestive tract down. Now some people will call this 24:22 gastroparesis. Um gastroparesis is actually different. 24:28 It is when we lose control over what’s happening in the in the colon like the 24:34 nerves and things like that just stop working. I have never seen that with the GLP1s that we prescribe in micro doing. 24:42 um it’s been documented. It can happen, but again it a lot of it is dosing and a 24:48 lot of it is staying on top of your client and what’s happening and what’s going on and what you’re doing and making sure that they do have good 24:54 motility still. So a lot of these things can be mitigated if you have problems 24:59 with them. Now one of the most profound effects of semiglutide occur in the 25:05 central nervous system. GLP-1 receptors are widely distributed in the brain 25:10 particularly in the hypothalamus and the brain stem area where we are involved in 25:15 appetite regulation. So when when wilding and colleagues published their 25:20 landmark step one trial in the New England Journal of Medicine in 2021, 25:25 they demonstrated that participants receiving 2.4 4 milligrams of semiglutide weekly achieved an average 25:32 weight loss of 14.9% of their body weight over 68 weeks. Now, I want you 25:39 guys to really understand this. We’re talking roughly 15% body weight loss 25:45 over a year, longer than a year. 52 weeks is a year, right? This is 68 25:50 weeks. So, it took longer for them to lose. We’re not talking about giving 25:55 somebody a dose to lose 15% of their body mass in a month or two. That that 26:01 is not healthy for any of us. That is not what we’re talking about doing here. Now, they compared this to placebo and 26:08 the placebo was only 2.4%. So, that is a significant difference. 26:14 And even beyond the numbers, patients reported something very qualitatively different, a reduction in what’s now 26:21 called food noise. Everybody knows what food noise is. We’ve talked about this long before GLP1. It’s that craving. 26:28 It’s that part of your brain that just keeps thinking about I want to eat something. You know, that was actually 26:34 reduced and they didn’t expect to see that happen. Now, this refers to the constant mental preoccupation with food, 26:42 the intrusive thoughts about eating, the difficulty in feeling satisfied. Semi-glutide appears to appears to 26:49 modulate reward pathways in the misolyic system reducing hedonic eating and food 26:57 cravings. Now there are also great cardiovascular effects of semiglutide 27:02 that extend beyond weight loss. Uh the sustained six and select trials 27:07 demonstrated significant reductions in major adverse cardiovascular events uh 27:14 mace in high-risisk populations. The select trial published in 2023 showed 27:20 that semiglutide reduced cardiovascular death, non-fatal myioardial inffection 27:25 and non-fatal stroke by 20% in adults with overweight or obesity and 27:31 established cardiovascular disease but without diabetes. So this suggests that 27:37 mechanisms beyond glucose control and weight loss possibly including 27:42 anti-inflammatory effects, improvements in endothelial function and favorable 27:47 changes to lipid profiles. Now I will tell you the clients that I work with that are on GLP1, 27:53 they will tell you that their inflammation has been significantly reduced. We are also seeing really 28:00 amazing results in lipid profiles. um part of its weight loss, but there is a 28:06 component to this that is lowering the triglyceride levels because it’s related to sugar and how the body’s processing 28:11 it. And we’re seeing better profiles, less need for statins as a result of 28:17 that. If if you want to listen to my episode on statins, I have one on that. Uh they are not my favorite medication. 28:24 I think it’s overprescribed and overused um and not really affecting or 28:29 addressing the problem. So these things can really be helpful. There’s also some 28:34 uh ramblings going on with GLP-1s saying that they may be able to help with 28:40 addiction in the future because of where they’re finding it affecting the brain and how it affects the food noise and 28:47 the cravings that we have for food and the addiction for food. Could it potentially help with other addictions 28:53 down the road? We’ll have to wait and see on that one. So semiglutide’s FDA prescribing information also includes a 29:00 box uh boxed warning about thyroid sea cell tumors. So in rodent studies 29:06 semiglutide caused dose dependent and treatment duration dependent sea cell 29:12 tumors at clinically relevant exposures. So while it’s unknown whether or not 29:17 semiglutide causes uh thyroid cancer tumors in humans and the rodent thyroid biology 29:26 differs significantly from humans, the drug is contraindicated in patients with a personal or family history of 29:33 medillary thyroid carcinoma or in patients with multiple endocrine neopl neoplasia syndrome type two. it is 29:42 uh contraindicated for safety effects with that. Um I have seen endocrinologists okay GLP1s to be used 29:50 in patients who’ve had other forms of thyroid cancer just not the meillary 29:55 thyroid cancer. So there is possibility there. Now the most common side effects 30:00 are gastrointestinal. It’s nausea affects about 20 to 44% of patients 30:06 depending on the formulation with diarrhea, vomiting, constipation, abdominal pain, and also frequently 30:13 reported in clinical trials. I see this in my clinic, too, especially dose dependent. Um, and it happens early on 30:20 when you’re first starting the medication, but seems to settle out over time. The one that I would add to this 30:26 that I don’t think they have on here is an increase in acid reflux. We also see that quite often uh especially in people 30:33 who suffer with acid reflux to begin with. Now these effects are typically most 30:40 pronounced during the escalation and they like I said often improve over time 30:45 but more serious but less common adverse effects include acute pancreatitis. 30:51 The medication needs to be discontinued immediately if this is confirmed. You can see some diabetic retinopathy 30:57 complications in patients with pre-existing retinopathy and acute kidney injury. Um, this usually happens 31:05 secondarily to dehydration from the GI effects. There are some gallbladder disease um that can occur and people who 31:13 have a sensitive gallbladder will describe uh discomfort with that. I’ve 31:18 even seen some people who’ve had their gallbladder out on GLP1s at the higher doses complain of similar pain that they 31:25 used to have when their gallbladder was in. So, really important to just kind of monitor these symptoms and work closely 31:32 with somebody that understands them and can be on top of them quite quickly if this happens. Excuse me. From an 31:39 integrative medicine perspective, semiglutide really represents a powerful tool, but it’s not a standalone 31:46 solution. Remember, the medication addresses one aspect of the metabolic dysfunction, the signaling systems 31:53 controlling appetite and glucose homeostasis, but it doesn’t address the root cause that led to the metabolic 32:00 disease in the first place. Patients who rely solely on the medication without addressing the ultrarocessed food 32:07 consumption, the ccadian disruptions, the chronic stress, the sleep apnea, or 32:12 underlying hormonal imbalances often experience weight regain when the medication is discontinued. 32:20 The drug is also not a substitute for addressing the emotional and psychological drivers of eating 32:26 behavior, including the unresolved trauma that may manifest as emotional eating. I think this is really important 32:33 because we don’t address the trauma issue enough with clients and we need to 32:38 be looking at that. There is a huge trauma effect out there these days that is I don’t want to say leading to or 32:45 causing but it is definitely contributing to chronic illness and it’s not being talked about enough. So we 32:52 really need to be talking about this and addressing this trauma aspect. Now the next GLP that one that I want to talk 32:59 about is trespathide. This is a dual agonist. It takes center stage. It is my 33:05 favorite GLP one. Trisepatide is marketed as Mangjaro for type 2 diabetes 33:11 and Zepbound for chronic weight management and it represents the next 33:16 evolution in increantbased therapy. This is a dual agonist a 39 amino acid 33:23 synthetic peptide structurally based on the human glucose dependent insulin tropic peptide so GIP sequence but 33:31 modified to activate both the GIP receptors and the GLP1 receptors. So the 33:37 addition of the GI GIP agonism to the GLP1 agonism appears to create this 33:46 synergistic effect that goes beyond simply adding the two mechanisms together. So the GIP like GLP-1 is an 33:55 increant hormone secreted by what is called the K cells in response to nutrient intake. It enhances glucose 34:02 dependent insulin secretion but it also effects on atapost tissue metabolism 34:09 potentially improving the insulin sensitivity in fat cells and influencing 34:14 how the body stores and metabolizes fat. So some research suggests that GIP may 34:20 also have effects on energy expenditure though this remains an area of 34:26 investigation. So basically what we’re saying is this drug may actually help 34:32 people who are insulin resistant or insulin sensitive, not just somebody who 34:38 has problems with glucose control. So, this is super exciting because it opens 34:43 up the door for all of these people for decades that we’ve been trying to manage with insulin resistance and trying to 34:50 prevent diabetes and honestly most of the time have been unsuccessful 34:56 unless you can keep your diet at 50 grams of carbs or less a day, which is extremely difficult. Um, and take some 35:04 supplements that may or may not work and or take some metformin that may or may not help. this drug actually really 35:11opens that up and helps in that capacity. So there was a clinical trial 35:17 called the surmount clinical trial which demonstrated that trespathide produces 35:22 even more substantial weight loss than semiglutide. In the surerount one trial published by uh J tree I might have said 35:31 that wrong. I apologize if I slaughtered your name and colleagues in the New York England Journal of Medicine in 2022. 35:38 Participants receiving the highest dose of trespide, which is 15 milligrams, achieved an average weight loss of 20.9% 35:47 of their body weight over 72 weeks, compared to 3.1% with placebo. This 35:54 level of weight loss approaches what’s typically only seen in beriatric surgery. So, this is amazing because if 36:02 this medication works and we don’t have to do beriatric surgery, stomach stapling basically, um, oh my gosh, it’s 36:11 amazing. There are so many complications and risks that go with stomach stapling and the different procedures that they 36:17 do these days. People don’t absorb their nutrients properly. They have to do liquid nutrients. It’s very complicated. 36:24 It’s very challenging. Many of these people gain their weight back. Um, and 36:30 this procedure is not fun to go through. So, if we could change that and change 36:35 the lives of people who’ve really been struggling, it is amazing. And I will tell you that I have seen this work. I 36:42 have seen people lose 100 150 pounds on these medications over a year or two 36:50 period of time. It is definitely slower than beriatric surgery on some standpoints, but that is okay. You don’t 36:56 want that rapid weight loss. It’s not good for you. It’s not healthy for you. It doesn’t look well. You know, we want 37:03 to do this safely and effectively in the best way that we can possibly do that for you. Now, the adverse effect profile 37:10 is similar to semiglutide. It’s dominated by gastrointestinal effects. 37:15 Nausea, diarrhea, decreased appetite, vomiting, constipation. These were all commonly reported in the surmount 37:22 trials. And like semiglutide, tricepide carries a blackbox warning regarding the 37:27 thyroid sea cell tumors based on the rodent data and it shares the same contra indications in patients with a 37:34 family history of thyroid cancer and men too. So the mechanism behind why 37:40 tepatide often produces more substantial weight loss than GLP-1. The agonism 37:45 alone remains under investigation, but it may relate to the complimentary effects on the different aspects of 37:51 energy homeostasis or to GIP’s effects on atapost tissue and potentially on 37:58 central central nervous system pathways that GLP1 alone doesn’t fully address. 38:03 Now patients often report even more profound reductions in food noise with tricepide compared to GLP1 and uh sorry 38:12 GLP1 the agonists through this is anecdotal and hasn’t been regularly 38:17 quantified in quality studies. So I’ve done both uh personally and in my 38:22 practice. I really like trespide better than semiglutide. For me I had too many side effects with semiglutide. uh I had 38:30 less side effects with trespathide. I also plateaued on semiglutide which I 38:35 didn’t really care for. And with Tresepide, I haven’t plateaued and I’ve been able 38:42 to lose about 25 pounds in um a year and a half and I’ve been able to maintain 38:49 that. Um and I continued to use it because I do have a strong family history of cardiovascular disease. And 38:56 if this could help me so that I don’t follow my family lineage with cardiovascular disease, I am all for 39:03 trying to do that. I’ve watched too many of my family members suffer from this. I’ve lost my dad at a very young age. I 39:09 lost my grandfather at a young age to it. All of their brothers to this. And I don’t want to be that same person. So 39:16 that is why I chose to do that. And I think it’s really important for us to take a look at that and understand that. 39:24 Now, I know this has been a really long podcast and I don’t typically do podcasts this long. I have a whole host 39:31 of information on additional peptides. So, I’m going to break this up for you 39:36 guys and I’m going to do another episode and we’re going to pick up where we left off here with these peptides so that we 39:43 can actually start to dive into different peptides as well. So, check 39:48 out my next podcast show when we’re going to dive into the peptides that 39:54 talk about sexual wellness, immune function, and all the other cool things 39:59 that we can do with peptides. So until then, remember to like, share, and 40:04 subscribe. It really helps us get out to other people and share our information, 40:10 and join us for our next episode as we continue the talk about peptides. 40:15 Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Please note that the views and 40:21 information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its 40:28 management, or our partners. Each affiliate, sponsor, and partner is an 40:34 independent entity with its own perspectives. Today’s content is provided forformational and educational 40:40 purposes only and should not be considered specific advice, whether financial, medical, or legal. While we 40:48 strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique 40:56 circumstances. We encourage you to consult with a qualified professional to address your 41:01 individual needs. Your use of information from this broadcast is entirely at your own risk. By continuing 41:08 to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its 41:14 associates harmless from any claims or damages arising from the use of this 41:20 content. We may update this disclaimer at any time and changes will take effect 41:26 immediately upon posting or broadcast. Thank you for tuning in. We hope you 41:31 find this episode both insightful and thought-provoking. Listener discretion 41:36 is advised.The post Episode 256 – How Peptides Work, Benefits, and FDA-Approved vs Off-Label Use Explained first appeared on Let's Talk Wellness Now.

Big Idea: It is one thing to be awakened and it is another to be saved. Do not rest in conviction.

Stroke Effects: What a Hemorrhagic Stroke Did to Jake Stroke effects aren't always obvious. Some show up immediately. Others arrive quietly, long after the hospital discharge papers are signed. For Jake, the stroke effects didn't end when his life was saved; they began there. Four months after a hemorrhagic stroke, Jake can walk, talk, think clearly, and hold a conversation that's thoughtful, articulate, and reflective. To someone passing him in the street, he might look “lucky.” But stroke effects don't ask for permission to be visible. They live beneath the surface, shaping movement, sensation, pain, identity, and recovery in ways few people prepare you for. This is what stroke did to Jake. The Stroke Effects That Came Without Warning Before his stroke, Jake's life was full and demanding. A husband. A father of four. An administrator coordinating drivers and operations. Active. Fit. Always moving toward the next opportunity. But in hindsight, the stroke effects were quietly signaling their arrival. Jake experienced severe headaches with a rapid onset. Nausea. Vomiting. Visual disturbances. At the time, they were dismissed as migraines. His blood pressure had been flagged as “pre-high” years earlier while living overseas, but after returning to Canada, he found himself without a regular doctor in an overloaded medical system. These were early stroke effects masquerading as manageable inconveniences. When the hemorrhagic stroke finally hit, it did so decisively, affecting the right side of his body, disrupting speech, movement, sensation, and cognition all at once. What Stroke Did to His Body One of the most misunderstood stroke effects is how specific and strange the deficits can be. Jake didn't just “lose strength.” He lost motor planning. When he tried to write the letter T, his brain sent the wrong instruction. Instead of a straight downward line, his hand looped as if writing an L. The muscles worked. The intention was there. The signal was wrong. To retrain that connection, he didn't practice ten times. He practiced thousands. This is one of the realities of stroke effects: recovery isn't about effort alone, it's about repetition at a scale most rehab programs don't explain clearly enough. Post-Stroke Pain: The Stroke Effect No One Warns You About If there's one stroke effect that dominates Jake's day-to-day experience, it's pain. Not soreness. Not discomfort. Neuropathic pain. Jake describes it as: Burning sensations Tingling Tightness, like plastic strapping wrapped around his limbs At its worst, a “12 out of 10” pain, like being tased while his hand is on fire This kind of post-stroke pain often resets overnight. One morning, he wakes up and feels almost normal. The next, the pain returns without warning, severe enough to stop him in his tracks. This is a stroke effect that confuses survivors and clinicians alike because it doesn't follow logic, effort, or consistency. It simply exists. And for many survivors, it's one of the hardest stroke effects to live with. The Non-Linear Reality of Stroke Effects Stroke recovery doesn't move forward in a straight line. Jake learned this quickly. One week brings noticeable gains. The next feels like a regression. Then progress returns quietly, unexpectedly. This non-linear pattern is itself a stroke effect. Early on, these fluctuations feel frightening. Survivors worry they're “going backwards.” But over time, patterns emerge. Rest days aren't failures. They're part of recovery. Silent healing days matter just as much as active ones. Understanding this changed how Jake viewed his recovery and how he measured progress. Identity Loss: An Overlooked Stroke Effect Some stroke effects don't show up on scans. Jake wasn't defined by his job, but work still mattered. Structure mattered. Contribution mattered. After the stroke, uncertainty crept in. Would he return to the same role? Could he handle the same responsibility? Should he? Stroke effects often force people to renegotiate identity, not because they want to, but because they must. The question shifts from “What do I do?” to “Who am I now?” For many survivors, this is one of the most emotionally demanding stroke effects of all. Recovery Begins With Action, Not Permission While hospitalized, Jake made a decision. He wouldn't wait passively. He brought in notebooks. Pencils. Hand grippers. Hair clippers. He practiced shaving, writing, and gripping, no matter how long it took. If writing the alphabet took all day, that was the day's work. By discharge, his writing had moved from scribbles to cursive. This wasn't luck. It was intentional engagement with stroke effects, meeting them head-on instead of avoiding them. What Stroke Effects Teach Us Jake's experience reveals something important: Stroke effects are not just medical outcomes. They are lived realities. They affect: How your body moves How pain shows up How progress feels How identity shifts How hope is tested And yet, understanding stroke effects, naming them, and normalizing them can reduce fear and isolation. That's why conversations like this matter. You're Not Alone With These Stroke Effects If you're early in recovery, you might recognize yourself in Jake's story. If you're years in, you might recognize where you've been. Either way, stroke effects don't mean the end of progress. They mean the beginning of a different kind of journey, one that rewards patience, repetition, and perspective. If you want to go deeper into recovery insights, lived experience, and hope-driven guidance: Learn more about the book here: The Unexpected Way That a Stroke Became the Best Thing That Happened Support the podcast and community here: Recovery After Stroke Patreon Final Thought Stroke effects don't define who you are, but they do shape how you recover. Jake's story reminds us that recovery isn't about returning to who you were. It's about learning how to live fully with what remains and discovering what's still possible. Disclaimer: This blog is for informational purposes only and does not constitute medical advice. Please consult your doctor before making any changes to your health or recovery plan. Living With Stroke Effects You Can't Always See Jake reveals the stroke effects that remained after the hospital—pain, motor issues, fatigue, and how he's navigating recovery four months on. Highlights: 00:00 Introduction and Background 05:10 Health Awareness and Signs 16:56 Personal Health Journey and Challenges 23:11 Recovery Process and Emotional Impact 38:28 Attitude Towards Recovery 46:30 Long-Term Recovery and Reflection 55:06 Work and Identity Post-Stroke 01:07:40 Pain Management and Coping Strategies 01:16:16 Community and Shared Experiences Transcript: Introduction and Background Bill Gasiamis (00:00) Today’s episode is one that really stayed with me long after we finished recording. You’re going to meet Jake, a stroke survivor who is very early in recovery and navigating the reality of what stroke actually does to a person long after the emergency has What makes this conversation so powerful isn’t just the hemorrhagic stroke Jake experienced. It’s how openly he talks about the stroke effects that followed. The pain, the confusion. the nonlinear recovery and the parts of stroke that are hard to explain unless you’ve lived them. I won’t give away Jake’s story that’s his to tell, but I will say this. If you’re early in recovery or you’re trying to make sense of symptoms that don’t quite fit the brochures or discharge notes, there’s a good chance you’ll hear something in Jake’s experience that feels confronting and reassuring at the same time. Now, before we get into the conversation, want to pause for a moment and say this, everything you hear, the interviews, the hosting, the editing exists because listeners like you help keep this podcast going. When you visit patreon.com slash recovery after stroke, you’re supporting my goal of recording a thousand episodes. So no stroke survivor has to ever feel like they’re navigating this if you’re looking for something you can lean on throughout your recovery or while supporting someone you love my book, the unexpected way that a stroke became the best thing that happened is available at recovery after stroke.com slash book. It’s the resource I wished I’d had when I was confused, overwhelmed and trying to understand what stroke had done to my life. all right. Now let’s get into the conversation with Jake. Bill (01:40) Jake Bordeaux, welcome to the podcast. Jake (01:42) Hi Bill, how are you this evening? Bill (01:44) I’m very well my friend. It is morning here. Just gone past 9am. We had a late night last night. We went to the opera and we saw Carmen. Jake (01:57) Hmm. How’s that? Bill (01:59) And for those who haven’t seen it, it’s in French and you have to read the subtitles because it has subtitles. I couldn’t read them because I was just a little too far. So I was squinting the whole night. But it’s a great opera, it was a great show, but we got home late so I’m quite tired. Jake (02:20) I couldn’t imagine that. Luckily I do speak French. So I wouldn’t need the subtitles, but that’s something I was afraid of actually, you know, coming out of the stroke is I was afraid almost that I had forgotten how to speak French or that I’d forgotten how to speak both languages. But luckily I speak ⁓ English and French. Bill (02:40) With a name like Bordeaux, I would definitely expect you to at least have some idea of French. Jake (02:45) Yes, indeed, sir. Half English and half French. I’ve been using that largely to my advantage. I’d been working up here in Northern Ontario with Federal Express. So I was working in administration here and sort of coordinating the management and the drivers being the liaison during the two during the day. so, you know, anytime the drivers might have equipment that needs any kind of repair or any kind of issues they might come up with on road as well as when they leave the station and when they come back into the station, I’m the guy that they would deal with. Bill (03:22) Wow, that’s cool. So tell me what was life like before stroke for you? What were you up to? What kind of things did you do? How did you spend your time? Jake (03:33) Well, life has had a lot of ups and downs for me in the last year’s bill. So, ⁓ I had been living for many years in, in Hong Kong and I’m originally from Canada and, I was born in the seventies, born in Ontario here. And by 2009, I had had various, you know, done grit, various career, choices or opportunities, job opportunities here. And I decided to. try my hand at a little something overseas. ⁓ I had an opportunity with a fellow Canadian named Noah Fuller who brought me over wanting to show me how to get into the watch business. And being two ⁓ enthusiasts, you know, being, ⁓ you know, I’d say we were into watch modification, watch restoration, and we were wanting to get a little bit more into building custom parts and building out custom watches. ⁓ working with various ⁓ people, military groups, et cetera, at working on their watch project. So he asked me to come to Hong Kong, learn everything that he knew about the business, and hopefully show me what I was gonna get into over there. That worked out, and while I was over there, I met my wife, I love my wife, I’m still with her. Stroke Effects: Health Awareness and Signs I got together with my wife in 2009 when I had first arrived in Hong Kong and I got married to her in 2010. During that time, Noah unfortunately passed away, so I lost my business partner, but the business continued to grow. So over the years, the business grew with my wife and I running that on our own. ⁓ Unfortunately, maybe it got some of the attention on the world stage. There’s been a lot of political, we’ll say issues in Hong Kong and leading into the pandemic, business was already suffering. ⁓ Once the pandemic hit and Hong Kong was locked down for a ⁓ big chunk of time. that really affected our business and took it down. By the time the pandemic had played its way out, our life over there was looking like it wasn’t panning out the way we’d wanted it to. And a lot of the opportunities that had been unfolding for us all of a sudden came to a close. ⁓ So we moved back to Canada. about two years ago and I started working up here and thinking about our next business opportunity. I’m a lot like you and I’m never really satisfied with what I’m doing and I kind of want to reach for the next thing and I kind of want to reach for more. So I like to work a lot. So while I was working on getting the next thing started, I was working with Federal Express. My days would be really, really busy. I would get up quite early in the morning and I’d chop wood here. I have a dog that I like to walk. I have a golden retriever. I have four children. So I have three girls and a boy and they’re ranging from four years old to 14 years old. They’re all in school. And of course, I was working full time at Federal Express and ⁓ working towards the next thing. So I guess life was pretty active. Bill (07:27) Pretty helpful. Did you have any sense that, you know, with regards to your health, things might take a turn? Was there any information coming to you that you might see now kind of in hindsight and go, well, that was probably a sign. Jake (07:45) Yeah, Bill. So I’ve watched a lot of your podcasts and I found them particularly helpful, especially a lot of the ones relating to hemorrhagic stroke. ⁓ Reason being that’s what happened to me. So ⁓ I had a hemorrhagic stroke ⁓ and it took out a large part of ⁓ my capabilities, I guess, mobility on my right side. So a lot of my body that’s affected is my right side. ⁓ Now, when I got back here from Hong Kong to Canada, unfortunately, I came here to a little bit of an overloaded medical system, to say the least. So I’m hoping that maybe some of what we’re talking today might help people who are in Canada if they suffer the ⁓ same thing as I did to try and get them on track for us, get them back into recovery. ⁓ When I arrived here, the system was overloaded. I didn’t have a doctor. So unfortunately, while I had been warned for several years that I had pre high blood pressure and ⁓ the doctors in Hong Kong had been, you know, monitoring my blood pressure and keeping a pretty close eye on things after arriving here in Canada, that wasn’t a case. And so you know, it would look now that I think about it, that I was having some warning signs. I was having headaches and I’d say that some of those headaches were pretty severe. ⁓ The headaches would come on like a, like a very fast, ⁓ fast onset headache. I would get very nauseated very quickly. ⁓ And then sort of, would, I’d vomit the headache. would pass. At first, I thought I was getting migraine headaches. I’d had one when I was a lot younger. But ⁓ these were coming with some visual disturbance. I was having this horrible headache. was having nausea. So all the things you might expect from a migraine, except that it was going away within minutes and all of a sudden I was back at work. you know, in hindsight, that definitely was ⁓ a warning flashes. And ⁓ had I had a proper physician, if I had somebody watching out for me, they may have caught that. I don’t know, there’s no way for us to know that. So what I would say is, if anybody’s having pretty high blood pressure, keep an eye on that. I would say my blood pressure when I had the stroke was quite high. And if I had been monitoring that, I might’ve been on top of it. So would you like to hear about the day that it happened or? Bill (10:45) Yeah, I would in a moment. So with the blood pressure in Hong Kong, were you being monitored and also medicated or was it just you were being monitored? Bill Gasiamis (10:56) We’ll get back to Jake’s story in just a moment. I want to pause for a second and ask you something important. Why do you listen to this podcast? For many people, it’s because they finally hear someone who understands what they’re going through or because they learn something that helps them make sense of their own stroke effects without feeling overwhelmed or alone. And here’s the part most listeners never really think podcast only exists because people like you help keep it There’s no big company behind it. No medical organization funding the work. It’s just me, a fellow stroke survivor doing everything I can to make sure these conversations are available for the next person who wakes up after a stroke and doesn’t know what comes One of the biggest challenges after stroke is finding reliable information without spending years searching, reading and second guessing yourself. That’s why I want to mention turn2.ai. Turn2 isn’t a sponsor, it’s a tool I personally use. If you choose to sign up using my affiliate link, you’ll get 10 % off and I’ll receive a small commission and no extra cost to you. That commission helps support the podcast and keep these conversations free. What Turn2 does is simple but powerful. It saves you time. Instead of spending years trying to track down research, discussions and updates about stroke, Turn2 brings relevant information straight to you. If you’re already dealing with fatigue, pain or cognitive overload, saving time and mental energy matters. And if you want to go deeper on your recovery journey, you can also grab my book, The Unexpected Way That a Stroke Became the Best Thing That Happened at recoveryafterstroke.com slash book. If this podcast has helped you feel understood even once, consider supporting the mission in whatever way feels right for you. All right, let’s get back to Jake. Jake (12:46) No, so I wasn’t being medicated for high blood pressure at all. was kind of these, well, it’s not quite severe enough to really do anything about it, so we’ll just keep an eye on it. ⁓ I did have pre-existing ⁓ medical issues. When I was quite a lot younger, I had suffered from ⁓ what some people might call Crohn’s disease or an inflammatory bowel issue. and I had some back pain. But other than that, I wasn’t really on any other types of medications. I wasn’t on any kinds of blood pressure medications, any kind of heart medications. ⁓ I wasn’t on any kind of antidepressants or anything like that. ⁓ I would say that I was pretty much feeling like I was in fairly good shape. haven’t gained or lost a heck of a lot of weight since the stroke. So what you see is what you get. wasn’t overweight. I wasn’t eating a lot of junk. I don’t smoke cigarettes. So. Bill (13:56) Yeah. One of those things. I know what you mean. Like I’ve been diagnosed with high blood pressure in the last six months and headaches. Jake, I’ve had headaches for years. I’m talking maybe four or five years. And at the beginning, they were intermittent. They would come and go similar to what you mentioned. And I would be able to get through the day. And I thought they were migraines, although nobody really convinced me that they were migraines. I couldn’t really say. That sounds familiar if I look up what migraine is and all the people who I’ve ever asked about a migraine, it never sounded like, I was never convinced by it. And then a little while ago, was at home, excuse me, I was at home with my wife, feeling really unwell. Did my, checked my blood pressure and it was about 170 over 110, 120, somewhere there. And that was, I knew that’s way too high, know, previously. I’ve checked my blood pressure maybe on the on perfect day and it was 120 over 80. So for me that was pretty serious. We went to the hospital because of all my history and they said your blood pressure is high. It’s probably a migraine causing you to have a migraine which is then causing your blood pressure to go high rather than the other way around. They didn’t say it’s high blood pressure is causing the migraine and or the headache. And then they put me on some migraine medication and they said, if we give you this migraine medication, it’s going to knock you out. You’re going to sleep, but you should wake up without a headache. Well, I woke up with a headache. The migraine medication didn’t do anything. So within a couple of weeks of that particular hospitalization and then going to my general practitioner, he prescribed me a blood pressure medication, came to start on it’s called to help keep the blood pressure down. Now I’m trying to get to the bottom of why do I have high blood pressure? That’s the part that’s frustrating me, because no one can tell you why you have high blood pressure unless they check your arteries and they’re half clogged or you’ve got some other issues with your heart or something like that. And I don’t have any of those issues. So now ⁓ it’s one of those things. It’s kind of like, well, you have high blood pressure. It might be something that runs in your family. When I check with my dad, my dad says that he has high blood pressure. My dad’s 84. So it’s like, you know, and he says, I started taking blood pressure medication at around 50, which is my age. But that’s still, that’s not good enough for me. Like I’m still not comfortable with, well, your dad did. So you are, and then therefore, just move on with life, take this tablet and then move on. Now I’m happy to take the tablet because I do not want to have another hemorrhagic stroke. I’m very comfortable taking a tablet to prevent that, right? No trauma, no traumas. Personal Health Journey, Stroke Effects, and Challenges But ⁓ it’s a very interesting place to find myself in after going through all the three brain hemorrhages that I’ve already had since 2012, brain surgery, learning how to walk again. Now I’ve had enough. I don’t want… I don’t want to be doing this anymore, even though I am finding myself here and I’m tackling it. Part of me is going, man, this is too much. Why do we need to go through this now? Jake (17:29) Yeah, I wanted to ask you something actually, maybe if you’ve had the same, you brought something back to mind here, is that one thing I did have, again, in hindsight, I had visual disturbance. in 2018, my grandmother, bless her shit, my grandmother passed away and I was abroad and I took it pretty hard. was largely raised by my grandfather, my grandmother. And I took it, it was very emotional. And ⁓ when I was grieving, I had an episode where I had a rather bad headache. And again, I had one of these feelings, like I thought I had a migraine headache. Maybe I did, or maybe we’re reading something into it. But coming out of that, I had a visual problem. And it was one of my eyes. in my right eye, you know, again, I have my issues now with my right hand side. My right eye had gotten quite blurry. I was having ⁓ issues with my vision in my right eye. And ⁓ a doctor had decided that, well, maybe it’s a form of macular degeneration. And he decided to do a laser surgery. at the time in Hong Kong. However, it didn’t have any effect. It didn’t help me out at all. And the only thing that helped that was time. And I wonder again now if the reason why treating the eye didn’t take any effect is because he should have been treating or looking at the brain. I think that maybe the issue might have been a small stroke to begin with. and I didn’t realize it at the time. Bill (19:25) That sounds very plausible, right? That’s I think probably a very logical conclusion to get to. Sometimes, you you hear people lose their vision and the way they discovered they’ve had a stroke is they’ll go to the ophthalmologist and they’ll say, I can’t see. And the guy will go, well, your eye looks perfect. I there’s nothing wrong with your lens. There’s nothing wrong with the macula. The eye pressure is fine. Everything’s fine. And that definitely suggests that there is a ⁓ neurological issue of some kind, right? So it’s like, next step is go to the hospital, get it checked out. But ⁓ yeah, well, there’ll be no way of knowing, but I science, I had similar kind of things happen about a year and a half before my first bleed. was at our local football here, which ⁓ my team made the what we call the grand final. There’s usually a playoff series and then the last two teams get to the final game of the year and then the one that wins wins the championship. And my team made it and I was there cheering them on, screaming my head off, you know, just being a really passionate supporter and went home that weekend with a massive headache that lasted about five days and ended up in hospital. They did a lumbar puncture. They checked for a brain hemorrhage or anything along those lines and they didn’t find anything and they also didn’t find the faulty blood vessel that later would cause the first brain hemorrhage. But when I speak to people about it, everyone will say, well, we’ll never know, Bill. There’s no way of knowing whether they were linked. But in my mind, it’s pretty logical to conclude that that first massive five day headache was a sign that something wasn’t right in my brain. And although they had that suspicion of that, they didn’t know what they were looking for. So they couldn’t find the faulty blood vessel. just did a scan, a CT, sorry. Yeah, they just did a CT to actually see if there was any visible signs of a tumor or a bleed or something like that. And since there wasn’t, they weren’t able to diagnose the faulty blood vessel that would later. ⁓ bleed three times. Jake (21:55) That’s incredible, by the way, the three times thing, and that’s got to take a lot of strength to get through. ⁓ I don’t know if I had mentioned to you, how recent this has been. So ⁓ one thing that I’ve noticed with your podcast is that most of the guests who are on have had a considerable amount of time elapse in between when the event has taken place and when they’ve been able to get back lot of their capabilities, a lot of their abilities. So how long exactly did it take you to get back to the stage or the state that you’re in now? Bill (22:36) I would say that I had, ⁓ well, the first three years were tumultuous because every time I was on the road to recovery after the first bleed, then the second bleed happened, that was six weeks apart. And then after the second bleed, I was really unwell. ⁓ Memory issues, couldn’t type an email, couldn’t read, couldn’t drive, couldn’t work. Recovery Process and Emotional Impact angry, really angry. I was probably in that state for the best part of about six to nine months. And then it started to ease and settle down as the blood vessel stopped bleeding. And then the, and then the blood in my head started to dissipate and kind of dissolved, I suppose. And I think I thought everything was going fine. So between February, 2012 and November, 2014, that’s when I had the next bleed November, 2014. the third one. And then when I woke up from that, I had to learn how to walk again. So by the time I got to February 2015, I had been three years in you know, in the dungeon, you know, getting just smashed around by stroke again and again and again, and then brain surgery, then learning how to walk again. And I think personally, I turned the tide maybe at around 2018, 2019. So it took another three to four years for me to feel like even though I’m living with all these deficits, I have got enough of my cognitive function back, my physical function back to be able to go back to my painting company, which had been on pause for a number of years. yeah, so all up, you know, from first bleed, Jake (24:25) incredible. Bill (24:30) to back to the painting company, you know, it seven years. It was quite a long time. And I hear people have similar kind of stories about five, six, seven years. They’re still dealing with everything that the stroke caused, but they have some kind of a turn, like for the better, some kind of like a shift in whether it’s mindset, whether it’s emotionally or whether it’s physically, they have kind of some. Like a fork in the road moment where things change for the better. Jake (25:03) That’s incredibly inspiring for me. So yeah, you give me a lot of hope because I’ve been going through a lot and I’ve only been at this for four months now. so I had this stroke in late July and upon getting into the hospital, again, I wasn’t able to talk. I wasn’t able to use my, couldn’t move my right hand side at all. ⁓ I wasn’t able to go to the washroom, any of the things. I was basically left with kind of like ⁓ a blank slate and everything that I’ve gotten back has been pretty rapid. So I’m really extremely thankful for that, especially that, given that hemorrhagic strokes are rare, ⁓ consequences seem to be more severe and more often fatal. So, yeah, I’ve only been at this for a few months, Bill (26:10) Yeah, I was gonna ask what was it what happened on the day of the strike? What was it like? Jake (26:16) Yeah, so on the day of the stroke, let me get back there for just a second. Right, so on the day of, it was a pretty regular day and I had got up, it was a beautiful day, it was July. ⁓ My family had been on a trip recently, they’d gone to the nation’s capital and visited my family and I was happy to have them back. I just bought my wife a new bike and ⁓ I tuned it up. The dog had been out and I was starting work at 2 p.m. So I was about to go in for 2 p.m. and see the drivers for the whole second part of their day until the closing. ⁓ And I ⁓ was biking into work. again, I was incredibly active. ⁓ So I was biking to work and it would be generally about a 15 minute bike ride and it’s a lot of uphill, et cetera. And some of the route is through some residential areas and even some pathways that go through the woods. Again, I live in Canada and in particular in Northern Ontario in quite a small town named Kirkland called Kirkland Lake, which is a gold mining town. we’re in a gold mining boom right now. And so yeah, I was biking to work, feeling pretty good. ⁓ When I got to work, or when I was just getting to work, I was pretty close to being late ⁓ after messing around with the kids a little bit. And so I pushed myself a little bit harder than I usually do. ⁓ I got to work right on time. I got in a little bit winded. And I started getting my equipment together, got all of my equipment and headed to my office and headed to the window where I’d be greeting all of the drivers as they come into the station. And I started to feel a little bit dizzy. So my thinking was though, I probably just pushed it a little too hard and I probably should have had a drink of water. So I grabbed a drink of water. And ⁓ I sat back down at my desk and the first drivers started to come in. And as they started to come in, I started to feel like it was hard ⁓ to keep track of what they were saying. I was having a hard time concentrating and that’s really not like me. Usually I’m able to concentrate on four children, a wife, a pet, myself. And when I’m at work, I’m able to deal with the whole station full of FedEx workers, drivers, et cetera. So I started asking the drivers, can you just leave your things with me? I’m going to put them aside for a few minutes until I’m back in the game here. I think I’ve winded myself a bit. I’m just going to chill. And the equipment started to pile up, because it was one driver, two drivers. three drivers. And as this was starting to go on, I was looking over at a lady who was working next to me in the office. ⁓ And ⁓ I’m very lucky that she was there. And ⁓ I’ll let you know why in a second. But ⁓ I started to look at her and I started to look at the drivers. And I think at that point, she looked at me and ⁓ it struck her there’s something really not right with Jake. So she came over and started to ask me some questions and she started to try and direct the drivers away from me so that maybe they’d stop asking questions. And it became pretty apparent to her real quick ⁓ that I was having a stroke. Now, thankfully, this lady’s not usually sitting in the office next to me. It was one of those things where she just happened to be there this day and she happens to work with the fire brigade here. and she works with first responders and she’s incredibly well educated as far as first aid and strokes and heart attacks, et cetera. So she was able to recognize what was going on with me right away. ⁓ She had management and she had everybody ⁓ take a look at me and they had the first responders coming right away. The emergency crew showed up within minutes. and they started asking me all the appropriate questions and they started lifting me out of there and driving me away. So I got to work, I guess, at about 2 p.m. That was when my shift started. And ⁓ by 2.25, ⁓ my wife was walking home from the neighborhood park with our kids and heard an ambulance. go by here, not realizing it was me. I’d been taken off in the ambulance. They brought me to a nearby town and then they airlifted me to Sudbury, Ontario. I guess in our nearby town, they determined that yes, I was having a stroke. They did a very quick preliminary scan. They sent me to Sudbury, Ontario, where they started doing more scans and figured out exactly what was going on. Although the medical system had failed me and I didn’t have a doctor going into it, when the rubber hit the road there, they had it together and they got me the appropriate help as fast as possible. That’s probably what helped me to get my recovery online so quick. Bill (32:18) definitely does the time that you take to get to hospital makes a massive difference. That was a good outcome considering everything that was going wrong at the time. So then how does the hospital stay go? How long are you in the hospital and how does it play out? Jake (32:37) Yeah, so I arrived in in the hospital in in Sudbury and I was there for for a few days so ⁓ yeah, I was there for a few days and in that time my My ⁓ my wife and ⁓ one of my good friends one of our children there They managed to come and see me and from what they say I was incoherent at the time So I guess I was still able to talk ⁓ but what was coming out of me was a lot of garbled nonsense. I’ve seen some of your guests say, I thought I was saying, can you please hand me my bag and I need you to bring, and all that was coming out was sort of, blah, blah, blah, blah, like it wasn’t making any sense at all. ⁓ So I was in there for days. And once they had me stabilized in ⁓ Sudbury, Ontario, they decided to transfer me and I had my choice between a couple of different towns. So I would say that by the 25th, 24th, 25th, I was stabilized and I was heading to Sudbury on the 25th. ⁓ Once I arrived in Sudbury, I think I was visited, ⁓ by my folks and my wife and kids. And then I was sent to Timmins, Ontario for my actual recovery. So it was pretty fast. I had the stroke on the 21st and by the 26th, I was in Timmins where I’d spend the rest of my ⁓ recovery time. Bill (34:27) How did they deal with leaking blood vessel? Jake (34:30) ⁓ They didn’t. So they had determined that they were going to probably do a surgery. When they were taking me into the hospital, they had told me that there was a ⁓ brain hemorrhage, ⁓ that it was leaking, that they were going to be monitoring it, that it would be likely there would be a surgery, and that I should probably be be prepared not to make it through. ⁓ So I guess, you know, they gave me some hope. I mean, they told me that we can hope for the best, but they were quite honest with me at the time in saying you might be going for the rest of your life ⁓ wearing diapers or unable to talk. ⁓ And it’s quite probable that you might not make it out of this. Uh, so they monitored it and they continued to bring me while I was in the Sudbury for scans and they continued to monitor the situation. Um, but they didn’t do any surgery. So, uh, I was put on medications to bring the blood pressure down, to keep the blood pressure down. And, uh, and I was placed on those while I was in, in hospital. And I continued to. recover all the way through August. And by the end of August, I had come back home. ⁓ while I was in hospital, I was only visited twice because it was far away from, from my home. And, ⁓ I’m honestly, Bill, I’m glad. ⁓ I was really happy. I was able to see my, my, my wife and kids by phone, obviously, you know, the wonders of modern technology. ⁓ but I was left with a lot of time on my own to reflect and I was left with a lot of time on my own to get better. you know, one of the things I decided once I got to the hospital was I’m not going to spend any time in the lounge. I’m not going to spend any of the time with the other patients who are ⁓ in here, nothing against them or anything like that. But the very first thing I did, was I started to try and find more information about what exactly happened to me and ⁓ what are my chances of getting better and what gives me the best chances. And what I came up with was I had better start working on my recovery immediately. yeah, so one of the very first things that I did is I got my notebook into me. notebook, got pencils, I got a pencil sharpener, I got one of those, ⁓ you know, hand gripper ⁓ exercise, you know, for your hands. ⁓ And I got a razor blade, and I got my wife and kids to bring in a hair trimmer. And I decided that no matter how long it was going to take me to shave, I was going to do that on my own. no matter how long I thought I’m in here, I don’t have anything else to do today. If it’s going to take me all day to cut my hair and shave my face, I’m going to do that. ⁓ If it takes me all day to do the, write the alphabet down, I’m going to get through that. And I went from again, ⁓ scribbles from just scribbles and barely being able to hold onto the pencil to, ⁓ by the time I left the hospital, I was writing in perfect cursive. Attitude Towards Recovery Bill (38:22) Yeah, that’s brilliant. I love that attitude. That attitude is probably ⁓ something that holds people in very, like creates a great outcomes for people, regardless of how much the stroke has affected them, regardless of how bad their deficits are, you know, regardless of what version of stroke they caught, they, they had to experience. And this is what I was doing when I was in rehab as well. So I did the same thing when I came back from hospital. So My first stay, I came back and we were on the internet checking, you know, is a blade in the brain? What is all this stuff? What does it all mean? Trying to get some answers. The second time, ⁓ six weeks later, I was searching for what kind of food should I be eating? If I’ve had a stroke, what should I be avoiding, et cetera? That was pretty cool to find out and learn, wow, there is actually a protocol that you can ⁓ take that supports your brain health instead of one. that doesn’t support your brain health. So that was pretty awesome. And then ⁓ in rehab, I was searching YouTube for videos about neuroplasticity. was searching videos for ⁓ anything that had to do with recovery of a neurological challenge, et cetera. And it was just way better than being ⁓ sort of worrying about my own situation and focusing on me like. internalizing it, you know, I was externalizing it and becoming proactive and I found, ⁓ and I found some great meditations. So I’m lying there. I can’t walk. I’m very sleepy. I need to sleep most of the time because I’m exhausted from all of the rehab. I’ll put on a meditation and just let it do its thing in the background while I was healing, resting, you know, recuperating. ⁓ so I think that approach just changes the way that your body responds as well because your body wants to step up to the plate. If you set an intention, we’re going through the healing process, this is the path that we’re gonna take, the body follows. If you go through the other part, if you take the different path and go, well, things are not going good for us, we’re doing it really tough, we’re feeling sorry for ourselves, we’re not gonna put any extra effort in. the body’s going to go, no, I’m listening. I’ll do exactly what you want. And you get the results that, that your intention has set. Right. So I think that’s brilliant. The way that you went about that and not interacting with other people. kind of get that too, because it can bring you down. Like seeing other people doing it hard can bring you down. And also ⁓ sometimes other people’s attitudes can rub off as well. And they can bring you down if They’re feeling bad about this situation and you don’t want to be around people who are going to ruin your vibe. Doesn’t matter who they are or where they are. Jake (41:27) Right. And one thing that where I think the hospitals and doctors and therapy where I think they really let us down is something that I believe it was on one of your podcasts and someone talking about neuroplasticity is that when we do something for therapy, we should be doing it thousands of times. We shouldn’t be doing it a few times. I think where we’re let down is like, ⁓ for instance, I went for my physiotherapy today and I find it helpful and I definitely do go, I would recommend it to anybody. But we will do each of these exercises 10 times. Do this 10 times, do this 10 times, do this 10 times. But what we’re failing to see is that, you know, To really make those connections, need to do things hundreds or thousands of times. ⁓ I have a, know, a, for instance, for you, you know, I mentioned the writing. So a place where I have an incredible block is, ⁓ I will go to try and begin something, particularly where I’m going to write something down and I’ll have the intention of writing one thing and something different will come. So, I would try and begin a word with the letter T and instead of beginning by going up and then straight down and crossing my T, instead I’m doing a loop like it’s an L. So in order to, you know, retrain, sort of get that, get that connection made, to go and start doing words that begin with the letter T. Bill (43:17) I have Jake (43:24) and a lot of times, mean like thousands of times before I could sit down and write a letter T. if people are feeling like they’re not getting anywhere or it’s not coming along for them and they are doing the exercises, I would say don’t give up and do them more. Don’t give up and do them less, do them more. Bill (43:33) Wow. Jake (43:53) ⁓ If you’re going to be doing something like walking, if you’re finding that difficult, then I think maybe if you walked around the block on Tuesday, go another 10 steps further and do that for the following week and always just keep adding to it because it does get better. And I don’t know about you, do you find Bill like I know one of your recent guests mentioned that it was a challenge for him to deal with how non-linear the recovery is. And I think that only hearing that from other people allowed me to accept that. Because a lot of the time I’ll feel like I’m doing great and things are incredibly better. And then maybe I have a week where I’m doing in respects, I’m doing worse than I was when I was in hospital. And I think that that’s really hard to deal with. you have that too, or did you find that? The non-linear kind of feeling? Yeah. Bill (44:55) Indeed, and then what happens four months, five months, six months, 10 months, is you start seeing the pattern and the pattern is, okay, I’ve made some inroads, okay, here’s the quiet time or the downtime coming and then you feel better about it because it’s not a big deal. You see the pattern and you notice it and it’s less frustrating because that’s actually, it appears as though you’re doing nothing to your head. Your head might be going, oh, I’m not doing anything. Long-Term Recovery and Reflection sitting on my butt, I’m not able to get through a day of physical exertion or anything like that. I must be going backwards. Well, in fact, your body’s just doing a different version of recovery and it looks different. It looks still and it looks silent and it looks fatigued, but it isn’t going backwards. It’s just a different phase and it needs all of it. You need to do that silent, still, quiet, fatigued resting one. And then you need to do the one which is to whatever extent you can, full on, full out, doing too much, going too far, ⁓ over-exerting yourself. And they kind of, you can’t have one without the other. You have to have them both. And ⁓ if you understand that, then you don’t get anxious or upset about it or bothered about it. And you start playing the long game. You stop focusing on today, I didn’t have a lot of effort, but… If I reflect on my last six months or nine months, there was maybe only seven days that I was really low or didn’t feel great. The rest were better days or I felt okay or whatever it was. if you start playing when you’re only four months out, it’s hard to play the long game. But when you get to a year or 12 months out, you look back and reflect, you can see that majority of what you were doing was getting. outcomes that were favorable and therefore, you know, and therefore you can sort of be okay with the quiet days, rest, the rest of all those. I used to go to loud events, whether they were a concert, a family event, a party, wedding, whatever. If they were long drawn out days, I would have to plan for the next day to be completely a write off, nothing on the calendar. No going anywhere, seeing anybody, doing anything so that I could rest properly and get my brain back online so that I could have a good day, the third day, you know? And that’s how we did it for many, many years. And I remember one time when the shift came, when I said to my wife, I am not doing anything tomorrow. You make sure that whatever you do, you do without me. You’re going to go and do your thing, but I’m not going to be involved. And then waking up in the morning and going, hey, I feel fantastic. What are we doing today? And she’s like, I didn’t plan for you, but okay. ⁓ let’s get the ball rolling on something. So we did something minor, but it was more than nothing. And that was my, okay. My moment of things are shifting and I’m able to recover overnight with a good night’s sleep quicker than I was. doing previously. Jake (48:19) That’s great. That’s great. Yeah. A lot of this, I really appreciate talking to you and I appreciate hearing your guests who have been at this a lot longer than I have. ⁓ I’m incredibly encouraged by how well I’ve done so far, but it’s also, there’s a lot of questions. ⁓ For instance, I’m in this stage where I don’t know, Bill, if I’m going to make it back to the same job as I was doing before, don’t know whether it’s reasonable to think that. Right now I’m doing, you know, going through all the steps that I need to go through and doing all the evaluations that I need to do. ⁓ But I’m not sure what the outcome is going to be. And that’s a little bit hard because I’m, you know, like most people who are entrepreneurs or, you know, have large families, we like to have an element of control, you know, with things. So it’s been hard to just sort of sit back here and not know what’s coming along. As far as work goes, I don’t know. Luckily, you know, I have a building here where I do own the building and I do have commercial space downstairs. So maybe I have the option to now use that space for myself. And ⁓ maybe I’ll have to be, maybe I’ll be forced to go back into. entrepreneurship and open my own business. Maybe going back to work ⁓ is not the path for me. We’ll have to wait and see. Bill (49:56) It will emerge. You’ll get a sense of it. I had ⁓ three years where I worked for another organization and it was a completely different field and they were, the role was a very entry level administrative role. Very, we’re talking a role that would probably be replaced by AI now. ⁓ So we, I was doing that for three years and what was good about planning and trying to get back to that level of effort and work was that it served a purpose. And part of the purpose was talking to people, traveling, ⁓ doing work on the computer. It was retraining me as I was getting comfortable with the role, getting used to traveling, getting back to being in loud environments, et cetera. So it was difficult, was tiresome, it was challenging, but it was… kind of like its own therapy. And when it served its purpose after three years, I was done. I just said, okay, I’m out of here. going back to running my own business again. And I’ll be, I’ll do that as slowly or at my own pace in any other way that I can so that ⁓ I create the whole, all the rules around the amount of hours that I attend, the type of work that I take on. You know, so if I was too tired to work the following week, I would just tell my clients I’m busy for a week and I can book you in two weeks down the road, you know. So that was what was good about going back to my business. And also what was good about going back to a job for somebody else because their expectations, you know, working for a corporation, the expectations are far lower than the ones that we put on ourselves when we’re working. for ourselves. So I know some people think working for a corporation is really stressful and all that kind of stuff. And it probably is. No. But I mean, I was barely working six hours a day. Whereas working for myself six hours a day that the day’s just starting, you six hours. You haven’t even hit lunchtime yet. So it’s interesting to think about work and how ⁓ and how you can use it as a therapy. Jake (52:23) It is well, I mean the difference for me is that I was actually in that role that you’re explaining right now when I had the stroke so I I’d gone through a whole bunch of very difficult things in Hong Kong and upon coming back here to Canada, I was almost feeling like I I had a lot of stress going on and I had a lot of things that I needed to sort out and ⁓ there was a lot of things that we need to settle with the kids. There was all sorts of stuff that needed to be done. So the job that I was working was actually, it was already fulfilling that role that you explained. I was having that less responsibility. was going in for a specific amount of hours that they were letting me know. So that was exactly it. was an administration job, but it was really not close to the amount of responsibility that I was used to having. ironically, now that this has happened to me, it might be the amount of control that I have over the amount of worked that might be an advantage after going to stroke. I’d be interested to see or to hear more about ⁓ how people deal with the change that comes with the different type of work they might be forced into, forced out of, and how they deal with that. Because I think that a lot of people deal with, ⁓ they think of their employment or they deal with their life in this sort of way, like people often ask, especially in Asia. What do you do? The first thing that people do if you’re in Hong Kong is they hand you a business card. They call it a name card there. And the very first thing that you do when you meet somebody before you even speak is you hand them the card and you each examine each other’s cards. So this idea of like, what I do is who I am. And I, and I think that when you have something like this happen to you often what you do must change. when you’re identifying with what you do, you’re sort of declaring that as your title, who you are, I would imagine that’s pretty tough. Luckily, I wasn’t tied to Federal Express, thankfully. Work and Identity Post-Stroke Bill (55:00) Yeah, I hear you. is, people will work as a lawyer for 20 years or 30 years, have a stroke, and then it’s like, well, who am I now? What am I now? And that’s the challenge with working and identifying as the work that you do. know, those days are gone in theory. You know, you don’t get named John lawyer anymore. You don’t get named John banker. anymore, you you don’t get the your surname from the occupation that you do back in the day, you know, Baker, carpenter, plumber, you know, all those people, they were their entire job, they did it for 3040 5060 years, that was what they did. And then when they couldn’t work anymore, well, they still identified as john plumber, because they had the name, the name was given to them or John Carpenter or whomever. The thing about it is now with jobs being so ⁓ not long term anymore, you get a job or you go to a particular employer and then two, three years you’re in another role or another title, et cetera, ⁓ or you’ve moved up the corporate ladder, et cetera. Well, if you’ve never even done that, if you’ve only ever worked and you haven’t explored your interests, ⁓ hiking, walking, running, playing ball, ⁓ becoming a poker player, ⁓ whatever, whatever it is other than my job, you’re very, it’s understandable that it’s very narrow how you can explain to somebody how you occupy your time. Like what do you do? Well, I do plumbing, but I also do poker. ⁓ I do this, but I also do that. I’m that guy. Like when you ask me, sometimes I will literally be in a painting outfit, not so often now, but my painting clothes, and then I’ll take them off and I’ll sit in front of the computer and I’ll record a podcast episode. And then at the end of the day, I’ll be doing a presentation somewhere, speaking publicly on a particular topic at the moment. My favorite topic is post-traumatic growth. When somebody asks me, what do you do? If they know me, they know I do podcasting. They know I do painting. They know I do speaking. They know I’ve written a book. ⁓ they know all these things about me. If they don’t know me, depending on which room I’m in, I’m a podcaster. If I’m in one room, I’m an author. If I’m in another room, if I’m in another room, I’m a painter and so on. And what that allows me to do is. not be tied down to my entire existence being about only one thing, because I think that would be boring as, and I would hate to be the guy that only knows something about painting, how to paint the wall fantastically. mean, great, maybe, but not really rewarding, and not a lot of ⁓ spiritual and existential growth in painting a wall. I solve a problem for you, but I haven’t gained anything. other than money for me. It’s not really, you know, it’s not my cup of tea anymore. Now I get to have a podcast, I get to make way less money out of a podcast episode and yet reach hundreds and thousands of people and feel really amazing about that. And what that does is that fills up my cup. That allows me to fill up my cup on the down days where I’m not earning a living. And then it allows me to go earn a living. and then not feel like all I’m doing is working and going through the maze all day every day and just being on the constant cycle of the boredom and the sameness and all that kind of stuff. So I sprinkle a little bit of this and that into my life so that I don’t have ⁓ the same day twice because I can’t cope with the same day three times. Twice is a real bad sign for me. If there’s a third day coming, that’s gonna be the same as yesterday. I’m not up for that, I don’t want to know about it. Jake (59:21) Right. Well, that also helps with your recovery. I think like, as you say, you do a lot of different things and that helps a lot. Right. So, you know, one, for instance, is, know, the, of the first things I started to think of when I was in the hospital in Sudbury and thinking of getting home is my gosh, it’s going to start getting cold soon. Winter’s going to hit. And I really have to start getting that wood all stacked. Right. So So, you know, here I am, I’m benefiting from it now. I burn wood all winter, but, ⁓ you know, I spent a lot of my rehab ⁓ stacking wood. And I mean, that’s incredibly great physiotherapy, right? Whether you’re stacking wood or like you said, you made me think when you’re talking about painting, I’m thinking about like the karate kid, right? Like with wax on wax on paint on, this is the kind of stuff that gets you out of one particular mold. And with your brain sort of like focused on recovering in one single area, you can recover in all these different areas. And I think they contribute to like a big picture of your recovery. Bill (1:00:34) I agree with that. It’s exactly right. It’s you know standing on the ladder which I do less of these days because I Felt off about a year and a half ago. So standing on the ladder and Getting down the ladder holding a paint can and applying paint ⁓ Putting drop shades down and picking up tubs of paint, you know ⁓ That whole every part of that physical activity is using a different part of the brain. Writing a book, even if it’s only 10 minutes a day, writing half a page or 10 paragraphs or whatever it is, that uses a different part of the brain. ⁓ Public speaking, that trains and uses a different part of the brain. Everything that I do definitely kind of helps to rewire the brain in many, different ways and supports my ongoing recovery and… ⁓ is and the idea behind it amongst other things, the idea behind it from a neurological kind of perspective is that it activates more of the brain. The more of the brain that’s activated, the more chance you are of creating new neuronal pathways and having ⁓ more options for healing or recovery. And then it works emotionally for me, it works mentally for me. Do you know, so I get… the emotional fitness and the mental fitness out of it. Speaking on the podcast, meeting people gives back. you know, that serves my, I need to serve other people purpose. Do you know, like, it’s just so much, everyone ⁓ who knows me kind of knows that I wear a lot of hats. I kind of. I kind of like, I do it. I show people like when they’re saying, what are you up to today? I’ve been wearing a lot of hats today. And if I’m not wearing a hat, like I pretend that I put another one off or just took one off when I’m sitting with them or talking with them. It’s crazy how many things I do. And about the only hat I would prefer not to wear right now is I prefer to put the painting hat down. and just hand that over to somebody else and just go, I think that part of my life’s done and I’ll move on to other things. Jake (1:02:57) If you don’t mind, have one, there’s one more thing that right now that I’d like to mention just before I forget. Is that all right? All right. All right. So the only other thing, the thing that I’ve been dealing with myself and I don’t know how many people deal with it or don’t deal with it. I know that not everybody does. don’t, I deal with a lot of post, uh, post stroke pain. So while I don’t have Bill (1:03:04) Yeah, of course. Jake (1:03:25) ⁓ the misfortune of losing use of my feet or losing use of my hand. I mean, it’s limited. do therapy, but I’m able to use my hands. I’m able to write and all this. But coming along with that is an incredible amount of ⁓ burning, tingling ⁓ sort of ⁓ feelings like there is ⁓ almost like the, know, if you can think of newspapers when they’re delivered in a bundle and they’ve got this kind of plastic strapping around it. ⁓ It’s usually it’s yellow, you know, this sort of plastic strapping. I feel often like that is wrapped around my arms, like it’s wrapped around my leg. I deal with a lot of this kind of stuff, unfortunately. So again, I mean, I’m not going to sit here and whine about it because again, ⁓ I can walk, I can do all the things that I need to do and I’d rather have that than what I do. But I’m wondering if it’s really common for a lot of people to have this, you know, post stroke pain. Bill (1:04:44) If 10 was the worst pain you’ve ever experienced in your life, that’s like we’re talking about 10 is somebody’s cut your limb off ⁓ and one is no pain at all. Like where would the pain be for you? Jake (1:05:00) Well, thankfully, again, thankfully ⁓ I’ve had some progress in this. So when I first came to, when I was first starting to get all the feeling back, ⁓ I started to notice that some feeling wasn’t coming back. But while I was in the hospital, I was on quite a lot of medication. So I was on some pretty heavy painkillers. ⁓ I think hydro-morphone, things like this. And I came off of those when I was coming home and a lot of the feelings started coming back. I would say that some days and at some times that pain can be what I would say maybe it’s a 12 out of 10. Like it’s bad. at some points I’ve been left doing nothing but be able to just really just sit there and cry. I’m going to be honest with you. And the pain could be quite severe. Now luckily those days are few and far between. It’s not all the time. ⁓ And here’s the deal. The thing that’s very strange with the post stroke pain or the intensity of it is that it’s like going to sleep or it’s like the start of a new day, the beginning of a new day is like a reset button’s been hit. So for instance, I could wake up on a Monday and I could be hit with the worst pain that I’ve ever had in my life. It feels literally like I’m being hit with a taser gun on the right side of my body and that while somebody’s hitting it with the taser gun, they’ve lit my hand on fire. And, ⁓ And then the very next day after I’ve gone to sleep, I woke up and I’ve had the rest. I wake up almost scared to move because for me, sort of when I wake up and I haven’t moved yet, it’s almost like nothing’s happened to me. It’s like I wake up and I don’t know that I’m numb. don’t know that I’m in pain. don’t know that all this is going on. And then I start to move and sometimes I can sit there and feel a relief. Think, wow. There’s nothing severe going on. This is pretty good and it’s going to be a great day. Or sometimes I can be struck with a type of debilitating pain that I can’t even describe. Yeah. Pain Management and Coping Strategies Bill (1:07:34) Well, what you’re describing is very common. I know a lot of people going through post stroke pain. ⁓ It is a thing. I have a very minor version of exactly the thing that you described about how the tightness and things wrapped around ⁓ your hand, like the newspaper. that’s kind of what I feel on my left side, the whole left side all the time and the burning and tingling sensation all the time. And okay, on my worst days, these days, like it’s probably, you know, I know, it’s probably a four and a terrible one would be a five, but it doesn’t get there much. And what I’ve noticed is that the, either I’ve become more tolerant of it or my my pain has decreased in my awareness. Like I’m aware of the fact that my limb is in the state that it’s in. And sometimes I’ll go to get a massage to get the muscles loo

No BS Newshour Episode #401Media: May Cause Heartache, Hysteria & NauseaMainstream News is NOT independent. (0:04) How the press, the politicians and the pollsters conspire to  manipulate.Which paper goes down first - The Detroit Free Press or the Detroit News?(24:06) City Hall puts out a press release. They've fixed Detroit's Dirt scandal.   How this is not true says the demo contractor Mr. XAnd then there are the good reporters. (46:09) Tresa Baldas (Free Press) on Karen McDonald's Crumbly Case scandal.(53:35) Ross Jones (WXYZ) and George Hunter (Detroit News) exposé on the ex-con Detroit Police commissioner.Social Media is not the new media. Look no further than (57:30) Don Lemon and (1:02:18) Benny Johnson. ⁠NBN on YouTube⁠⁠: https://www.youtube.com/@NoBSNewshourNBN on iTunes⁠⁠: https://podcasts.apple.com/us/podcast/no-bs-newshour-with-charlie-leduff/id1754976617NBN on Spotify⁠⁠: https://open.spotify.com/show/0qMLWg6goiLQCRom8QNndC⁠⁠Like NBN on Facebook⁠⁠:  https://www.facebook.com/LeDuffCharlie⁠⁠Follow to NBN on Twitter : https://x.com/charlieleduff Sponsored by American Coney Island, Pinnacle Wealth Strategies, and XG Service Group

If you're pregnant right now, chances are your mornings—or really, your entire day—feel like a constant battle with nausea.

Kids can bring difficulty to marriage. We have to be vigilant to keep building our marriage while having kids.  Flexible in Marriage in Motherhood Eat, Wake, Sleep Cycle I use with my babies Works with Nursing or Breastfed babies Mama Natural Resource Other Episodes on Nursing Your baby from ME: Nursing Crash Course for First Time Moms Dealing with Emotional Ups and Down of Nursing a baby 5 tips for Success in Nursing Your Baby Breast Feeding to Lose Weight   **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

Today I'm sharing another personal healing testimony and what Bible mindsets I had to receive the healing Jesus purchased via the cross. I'll also be addressing some questions I've received about how I can believe that God wants all healthy, when not everyone IS walking in healthYou'll hear today:The danger of building a theology based off of experience and not what the Bible saysWhy people are sick if God wants everyone healthyWhere scripture shows us God is not the one making you sick and why it's also not him, even if he uses it for goodThe importance of knowing the Word of God and what your inheritance is in ChristThe thing Satan wants to steal from youOur responsibility to share the Gospel message in its fullness but not to make people believe itHow we can know from Jesus' healing ministry that God wants all wellThe different things Jesus purchased for you on the crossThe simple and effective way to speak to your sick or injured body, outlined by Jesus for us in the GospelsThe persecution even Jesus had for his teachings about healingEpisodes mentioned:Healing ones: ⁠⁠What Blind Bartimaeus and I Both Did for Healing (I got my singing voice back after almost a year of not being able to sing)⁠⁠⁠⁠Learn to Speak to Nausea, Period Cramps or Any Sickness or Injury Like Jesus Would⁠⁠⁠⁠Mark 11:23 is a SUPER Handy Tool When Dealing with Sickness or Injuries⁠⁠⁠⁠Jesus Wants You Free of Anxiety (Bible Based Advice that Has Worked for Me)⁠⁠The Identity Shift that Unlocked Asthma Healing⁠⁠⁠⁠⁠⁠Why a Headache was Healed on Day 4 and Not Day 1 (God revealed I had THIS wrong mindset preventing my healing)⁠⁠⁠⁠Why I Stopped Watching the Chosen (it has to do with health)⁠⁠⁠⁠Taking Communion Can Heal Your Complicated Relationship With Food⁠⁠Connect with Nyla:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nyla's IG ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nyla's website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nyla's Christian business podcast On the Job with God⁠⁠⁠

This is may be a little different than what I usually talk about on my podcast, but I had some pretty interesting thought break throughs that I thought I would share them. Maybe it will help at least one of you, I hope!  Email me at: positivityinpregnancy@gmail.com **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: Positiveinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Success in Second Trimester INTIMACY Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy Intimacy in the First Trimester Episode YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

This hypnosis session was for a pregnant client to help ease nausea, to reduce the intensity, and help them feel better able to manage any feelings of sickness. To access a subscriber-only version with no intro, outro, explanation, or ad breaks and 24 hours earlier than everyone else, tap 'Subscribe' nearby or click the following link.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://creators.spotify.com/pod/profile/adam-cox858/subscribe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Are you going back to work? Are you able to stay home? I have tips for both!  Feeling Alone in Pregnancy Eat, Wake, Sleep Cycle I use with my babies Works with Nursing or Breastfed babies Mama Natural Resource Other Episodes on Nursing Your baby from ME: Nursing Crash Course for First Time Moms Dealing with Emotional Ups and Down of Nursing a baby 5 tips for Success in Nursing Your Baby Breast Feeding to Lose Weight   **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

On this episode of Vitality Radio, we revisit the Grandma Was Right series to explore the therapeutic use of cayenne pepper and ginger root—two traditional remedies used for centuries to support circulation, digestion, and recovery. Jared explains why these warming herbs were historically used during illness rather than avoided, how they help restore blood flow, support digestive function, and ease aches and stiffness, and what modern research reveals about compounds like capsaicin and gingerols. You'll also learn how to use cayenne and ginger safely, how they complement each other, and why simple, time-tested remedies still matter today.Cayenne and Ginger Products DiscussedBuy KAL Think Magnesium L-Threonate AND Lifeseasons Lion's Mane Mushroom together and save $28! Vitality Radio POW! Product of the Week with PROMO CODE: POW22Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Are you ready to be intimate? Not ready? Intimacy can be a hard thing for some women after having babies. This episode has some tips and encouragement to help you in this season.  Email me on if you want me to continue doing postpartum or get back to pregnancy podcasts!: positivityinpregnancy@gmail.com Spark Love in Your Marriage and Motherhood Let's Get Awkward: Intimacy and Pleasure in Your Marriage Mama Natural Resource for week 8 postpartum Other Episodes on Nursing Your baby from ME: Nursing Crash Course for First Time Moms Dealing with Emotional Ups and Down of Nursing a baby 5 tips for Success in Nursing Your Baby Breast Feeding to Lose Weight Eat, Wake, Sleep Cycle I use with my babies Works with Nursing or Breastfed babies **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

Today I have a former Intuitive Eating coaching client on the podcast. Maddie is now a dear friend and has such a heart to give God glory in all she does. In this episode, you'll hear her share how God used this podcast to build her faith up for believing for healing in her own body. We both pray this episode draws you closer to the Father and gets you excited to dig into scripture yourself to see how the Bible talks about receiving healing.Scriptures mentioned: Mark 5:27-29 + 33-3427 When she heard about Jesus, she came up behind him in the crowd and touched his cloak, 28 because she thought, “If I just touch his clothes, I will be healed.” 29 Immediately her bleeding stopped and she felt in her body that she was freed from her suffering.33 Then the woman, knowing what had happened to her, came and fell at his feet and, trembling with fear, told him the whole truth. 34 He said to her, “Daughter, your faith has healed you. Go in peace and be freed from your suffering.”Past episode mentioned:Why I'm Certain Based on Scripture that God Wants Everyone HealthyMark 11 Teaches us How to Find Relief From Pain in Our BodiesLearn to Speak to Nausea, Period Cramps or Any Sickness or Injury Like Jesus WouldHow Jesus Healed Me of Dairy, Gluten, Citrus & Peanut IntolerancesWhat Blind Bartimaeus and I Both Did for Healing (I got my singing voice back after almost a year of not being able to sing)Connect with Nyla:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠IG⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nyla's second podcast, On the Job with God Christian Business Podcast

Sometimes helping out kids with projects can be frustrating. Thinking ahead on how you respond can help it be a smoother process.  Email me at: positivityinpregnancy@gmail.com **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: Positiveinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Success in Second Trimester INTIMACY Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy Intimacy in the First Trimester Episode YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

Nausea shouldn't be the most memorable part of surgery. We take a clear, evidence-based look at postoperative nausea and vomiting, from identifying who's at risk to building smarter prophylaxis bundles and choosing the right rescue when prevention falls short. With guest insights from Dr. Connie Chung, we unpack the Fourth Consensus Guidelines, translate them into practical workflows, and explore how Amisulpride—an atypical D2 antagonist—changes the game with an FDA indication for rescue after failed prophylaxis.We start by shrinking baseline risk: consider regional anesthesia when feasible, leverage TIVA with propofol, avoid nitrous and volatiles in longer cases, hydrate well, and spare opioids with multimodal analgesia. Then we scale prophylaxis to risk: dexamethasone at induction, 5-HT3 antagonists at the end, transdermal scopolamine for select patients, and low-dose Droperidol where appropriate. When prophylaxis fails, we explain why repeating ondansetron rarely helps and how switching classes boosts rescue success. Along the way, we map the safety terrain for D2 antagonists—QT prolongation, extrapyramidal risks, anticholinergic effects—so you can individualize care for elderly patients, those on antipsychotics, or anyone with potential drug interactions.We also dig into what's new: contemporary analyses of Droperidol at antiemetic doses, and growing evidence that Amisulpride pairs well with Ondansetron or Dexamethasone to improve outcomes. Pediatric pearls include TIVA, fluids, and a two-drug prophylaxis backbone for longer or higher-risk cases. The result is a practical, stepwise approach you can apply tomorrow—reduce risk, layer mechanisms, and rescue smartly—to cut PACU delays, avoid unplanned admissions, and deliver a recovery that feels as good as the surgical fix.If this deep dive helps your practice, follow, share with your team, and leave a quick review to help others find the show. Tell us your go-to PONV bundle and whether your site stocks Amisulpride.For show notes & transcript, visit our episode page at apsf.org: https://www.apsf.org/podcast/287-a-new-era-for-ponv-safety-guidelines-and-smarter-rescue/© 2025, The Anesthesia Patient Safety Foundation

Patience is a process that takes time and effort. I am still learning this one but I also have come a long ways! It is worth the effort!  Email me: positivityinpregnancy@gmail.com Mama Natural Resource Other Episodes on Nursing Your baby from ME: Nursing Crash Course for First Time Moms Dealing with Emotional Ups and Down of Nursing a baby 5 tips for Success in Nursing Your Baby Breast Feeding to Lose Weight Eat, Wake, Sleep Cycle I use with my babies Works with Nursing or Breastfed babies **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

This episode originally aired as #432 on 5/22/24 and we are bringing it to you again! Parasite cleansing has become a hot topic in the natural health world, but it can feel a little overwhelming. Are you confused about where to start or how to do a cleanse yourself? On this episode of Vitality Radio, Jared demystifies the process by sharing his experience along with his wife's, and a thorough breakdown of the entire process, the products, and what to expect. You'll learn a couple of ways to approach parasite cleansing and which one might be right for you or your family, including kids.  If you never thought about parasites being a problem in America, think again! For a deeper understanding of why parasites are indeed a bigger problem than is understood by most, be sure to listen to Jared's interviews with Dr. Todd Watts and Dr. Jay Davidson - the founders of CellCore.Products:CellCore Para KitVitality Nutrition Parasite CleanseVital 5 Precision Probiotic Vital SporesMagnesium BisglycinateCellCore Bowel MoverLife Seasons Regulari-TRedmond RelyteTrace Minerals Endure Drops***Inquire for capsule-free protocol Additional Information:For information on coaching options and personalized support, please email jessica@vitalitynutrition.comVitality Wellness Community Detox & Support GroupVitality Radio Podcast Listener Community#359: Comprehensive Detoxification of Parasites, Lyme, and Other Toxins With Dr. Todd Watts of CellCore Biosciences#431: Are Parasites Part of Your Health Concerns? With Dr. Jay Davidson#385: Rebalancing and Healing the Body Through Functional Medicine Detoxification With Dr. Stephen Cabral#258: Your Magnesium User's Guide***Be sure to check out all of the Emotional Vitality Episodes, including Jen's Story mentioned in this showVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Addictions. Sugar is one of my addictions. I feel the need and desire to take a break with sugar in the new year! Join me! 40 day sugar fast 40 day social media fast Email me at: positivityinpregnancy@gmail.com **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: Positiveinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Success in Second Trimester INTIMACY Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy Intimacy in the First Trimester Episode YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

Short breaks can really help you mentally, if you are struggling postpartum.  Email me: positivityinpregnancy@gmail.com Mama Natural Resource Other Episodes on Nursing Your baby from ME: Nursing Crash Course for First Time Moms Dealing with Emotional Ups and Down of Nursing a baby 5 tips for Success in Nursing Your Baby Breast Feeding to Lose Weight Eat, Wake, Sleep Cycle I use with my babies Works with Nursing or Breastfed babies **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

https://www.orderappai.com/Millions on GLP-1 face restaurant anxiety, but dining out doesn't have to trigger nausea. Discover exactly what to order, which foods to avoid, and the smart strategies that let GLP-1 users enjoy meals confidently while staying on track with their goals. Orderappai City: Needham Address: Boston Ma Website: https://www.orderappai.com/ Email: melissa@orderappai.com

This is probably the busiest month of the year. Start thinking ahead as you complete some of those things needing to be done this month.  With JESUS you CAN!  Dealing with Overwhelm in December 40 day sugar fast 40 day social media fast Email me at: positivityinpregnancy@gmail.com **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: Positiveinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Success in Second Trimester INTIMACY Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy Intimacy in the First Trimester Episode YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

Today I am sharing another new song. This time, it's all about what Jesus' BACK purchased for us and how to walk in that divine healing and health. Sick, injured? Know a loved one physically struggling? This episode is the one you need, friend. Be blessed!Past episode mentioned:Why I'm Certain Based on Scripture that God Wants Everyone HealthyLearn to Speak to Nausea, Period Cramps or Any Sickness or Injury Like Jesus WouldPicture Jesus' Back and Watch Sickness & Injury FLEE!Taking Communion Can Heal Your Complicated Relationship With FoodWhy I'm Not Afraid to Take Communion Carbs AnymoreCast Out Demons & Knowing if it's a Spirit of FearWhy it's Illegal for Sickness to Live in the Body of a BelieverConnect with Nyla:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠IG⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nyla's second podcast, On the Job with God Christian Business Podcast

Today I give a few tips to help you and baby find more positivity during this newborn and postpartum phase.  Mama Natural Resource Other Episodes on Nursing Your baby from ME: Nursing Crash Course for First Time Moms Dealing with Emotional Ups and Down of Nursing a baby 5 tips for Success in Nursing Your Baby Breast Feeding to Lose Weight Eat, Wake, Sleep Cycle I use with my babies Works with Nursing or Breastfed babies **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

Today is a testimony/teaching style episode. Let's study together the powerful healing story of Blind Bartimaeus found in Mark 10. I also share what he and I had in common in receiving healing from Jesus.I share today:Why corresponding action to show your faith is importantWhat Jesus purchased for you on the cross on top of forgiveness of sins (it's a lot!)A scripture that tells us God's will for all being healed doesn't just automatically happen Why you need to know what belongs to you as a child of God, so Satan doesn't steal it from you. Past episodes mentioned: ⁠⁠Learn to Speak to Nausea, Period Cramps or Any Sickness or Injury Like Jesus Would⁠⁠⁠⁠The Identity Shift that Unlocked Asthma Healing (you are ALREADY healed!)⁠⁠⁠⁠⁠⁠Does God Make us Sick? (Is God Actually Sovereign Over Our Health & Life? Part 1)⁠⁠Connect with Nyla:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nyla's IG ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nyla's website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nyla's Christian business podcast On the Job with God⁠⁠⁠

This week we are talking about Pancreatic cancer.  This is a type of cancer that begins as a growth of cells in the pancreas. The pancreas lies behind the lower part of the stomach. It makes enzymes that help digest food and hormones that help manage blood sugar. The most common type of pancreatic cancer is pancreatic ductal adenocarcinoma. This type begins in the cells that line the ducts that carry digestive enzymes out of the pancreas. Pancreatic cancer rarely is found at its early stages when the chance of curing it is greatest. This is because it often doesn't cause symptoms until after it has spread to other organs. Your health care team considers the extent of your pancreatic cancer when creating your treatment plan. Treatment options may include surgery, chemotherapy, radiation therapy or a mix of these. Pancreatic cancer often doesn't cause symptoms until the disease is advanced. When they happen, signs and symptoms of pancreatic cancer may include: Belly pain that spreads to the sides or back. Loss of appetite. Weight loss. Yellowing of the skin and the whites of the eyes, called jaundice. Light-colored or floating stools. Dark-colored urine. Itching. New diagnosis of diabetes or diabetes that's getting harder to control. Pain and swelling in an arm or leg, which might be caused by a blood clot. Tiredness or weakness. It's not clear what causes pancreatic cancer. Doctors have found some factors that might raise the risk of this type of cancer. These include smoking and having a family history of pancreatic cancer. Understanding the pancreas The pancreas is about 6 inches (15 centimeters) long and looks something like a pear lying on its side. It releases hormones, including insulin. These hormones help the body process the sugar in the foods you eat. The pancreas also makes digestive juices to help the body digest food and take in nutrients. How pancreatic cancer forms Pancreatic cancer happens when cells in the pancreas develop changes in their DNA. A cell's DNA holds the instructions that tell a cell what to do. In healthy cells, the instructions tell the cells to grow and multiply at a set rate. The cells die at a set time. In cancer cells, the changes give different instructions. The changes tell the cancer cells to make many more cells quickly. Cancer cells can keep living when healthy cells would die. This causes there to be too many cells. The cancer cells might form a mass called a tumor. The tumor can grow to invade and destroy healthy body tissue. In time, cancer cells can break away and spread to other parts of the body. Most pancreatic cancer begins in the cells that line the ducts of the pancreas. This type of cancer is called pancreatic ductal adenocarcinoma or pancreatic exocrine cancer. Less often, cancer can form in the hormone-producing cells or the neuroendocrine cells of the pancreas. These types of cancer are called pancreatic neuroendocrine tumors or pancreatic endocrine cancer. Risk factors Factors that might raise the risk of pancreatic cancer include: Smoking. Type 2 diabetes. Chronic inflammation of the pancreas, called pancreatitis. Family history of DNA changes that can increase cancer risk. These include changes in the BRCA2 gene, Lynch syndrome and familial atypical multiple mole melanoma (FAMMM) syndrome. Family history of pancreatic cancer. Obesity. Older age. Most people with pancreatic cancer are over 65. Drinking a lot of alcohol. As pancreatic cancer progresses, it can cause complications such as: Weight loss. People with pancreatic cancer might lose weight as the cancer uses more of the body's energy. Nausea and vomiting caused by cancer treatments or a cancer pressing on the stomach might make it hard to eat. Sometimes the body has trouble getting nutrients from food because the pancreas isn't making enough digestive juices. Jaundice. Pancreatic cancer that blocks the liver's bile duct can cause jaundice. Signs include yellowing of the skin and the whites of the eyes. Jaundice can cause dark-colored urine and pale-colored stools. Jaundice often occurs without belly pain. If the bile duct is blocked, a plastic or metal tube called a stent can be put inside it. The stent helps hold the bile duct open. This is done using a procedure called endoscopic retrograde cholangiopancreatography, also called ERCP. During ERCP, a health care professional puts a long tube with a tiny camera, called an endoscope, down the throat. The tube goes through the stomach and into the upper part of the small intestine. The health professional puts a dye into the pancreatic ducts and bile ducts through a small tube that fits through the endoscope. The dye helps the ducts show up on imaging tests. The health professional uses those images to place a stent at the right spot in the duct to help hold it open. Pain. A growing tumor may press on nerves in your abdomen, causing pain that can become severe. Pain medications can help you feel more comfortable. Treatments, such as radiation and chemotherapy, might help slow tumor growth and provide some pain relief. When medicines aren't helping, a health care professional might suggest a celiac plexus block. This procedure uses a needle to put alcohol into the nerves that control pain in the belly. The alcohol stops the nerves from sending pain signals to the brain. Bowel blockage. Pancreatic cancer can grow into or press on the first part of the small intestine, called the duodenum. This can block the flow of digested food from the stomach into the intestines. A health care professional might suggest putting a tube called a stent in the small intestine to hold it open. Sometimes, it might help to have surgery to place a feeding tube. Or surgery can attach the stomach to a lower part of the intestines where the cancer isn't causing a blockage. Prevention Screening for people with a high risk of pancreatic cancer Screening uses tests to look for signs of pancreatic cancer in people who don't have symptoms. It might be an option if you have a very high risk of pancreatic cancer. Your risk might be high if you have a strong family history of pancreatic cancer or if you have an inherited DNA change that increases the risk of cancer. Pancreatic cancer screening might involve imaging tests, such as MRI and ultrasound. These tests are generally repeated every year. The goal of screening is to find pancreatic cancer when it's small and most likely to be cured. Research is ongoing, so it's not yet clear whether screening can lower the risk of dying of pancreatic cancer. There are risks to screening. This includes the chance of finding something that requires surgery but later turns out to not be cancer. Talk about the benefits and risks of pancreatic cancer screening with your health care team. Together you can decide whether screening is right for you. Genetic testing for cancer risk If you have a family history of pancreatic cancer, discuss it with a health care professional. The health professional can review your family history and help you understand whether genetic testing might be right for you. Genetic testing can find DNA changes that run in families and increase the risk of cancer. If you're interested in genetic testing, you might be referred to a genetic counselor or other health care professional trained in genetics. Ways to lower risk You might reduce your risk of pancreatic cancer if you: Stop smoking. If you smoke, talk to a member of your health care team about ways to help you stop. These might include support groups, medicines and nicotine replacement therapy. Maintain a healthy weight. If you are at a healthy weight, work to maintain it. If you need to lose weight, aim for a slow, steady weight loss of 1 to 2 pounds (0.5 to 1 kilogram) a week. To help you lose weight, exercise most days of the week. Slowly increase the amount of exercise you get. Choose a diet rich in vegetables, fruit and whole grains with smaller portions.  (CREDITS: MAYO CLINIC)

There are a lot of extra things this holiday season and that can add overwhelm to your life. Use these tips to help you through!  Email me at: positivityinpregnancy@gmail.com **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: Positiveinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Success in Second Trimester INTIMACY Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy Intimacy in the First Trimester Episode YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy

In this episode, we review the pharmacology, indications, adverse effects, and unique drug characteristics of 5-HT3 receptor antagonists such as ondansetron (Zofran) and palonosetron (Aloxi). Key Concepts There are four 5-HT3 (serotonin subtype 3) receptor antagonists on the market: ondansetron, granisetron, dolasetron, and palonosetron. These have primarily been studied for acute chemotherapy-induced nausea and vomiting (within 24 hours of chemotherapy administration) and for post-operative nausea and vomiting. When used for chemotherapy-induced nausea/vomiting, 5-HT3 receptor antagonists are given prior to chemotherapy (usually 30-60 minutes before) on day #1. They are not given on subsequent days because they are not as effective for delayed nausea and vomiting. Palonosetron has the longest half-life, longer binding affinity to the 5-HT3 receptor, and trends towards having the best efficacy among the 5-HT3 receptor antagonists. 5-HT3 receptor antagonists are associated with QTc prolongation and may cause headache, dizziness, constipation, or diarrhea. Their association with an increased risk of serotonin syndrome is controversial and not supported from a mechanistic perspective. References Simino GP, Marra LP, Andrade EI, et al. Efficacy, safety and effectiveness of ondansetron compared to other serotonin-3 receptor antagonists (5-HT3RAs) used to control chemotherapy-induced nausea and vomiting: systematic review and meta-analysis. Expert Rev Clin Pharmacol. 2016;9(9):1183-1194. doi:10.1080/17512433.2016.1190271 Tricco AC, Soobiah C, Blondal E, et al. Comparative efficacy of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis. BMC Med. 2015;13:136. Published 2015 Jun 18. doi:10.1186/s12916-015-0371-y Hesketh PJ, Kris MG, Basch E, et al. Antiemetics: ASCO Guideline Update. J Clin Oncol. 2020;38(24):2782-2797. doi:10.1200/JCO.20.01296 Herrstedt J, Clark-Snow R, Ruhlmann CH, et al. 2023 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting. ESMO Open. 2024;9(2):102195. doi:10.1016/j.esmoop.2023.102195 Rojas-Fernandez CH. Can 5-HT3 Antagonists Really Contribute to Serotonin Toxicity? A Call for Clarity and Pharmacological Law and Order. Drugs Real World Outcomes. 2014;1(1):3-5. doi:10.1007/s40801-014-0004-3 Li WS, van der Velden JM, Ganesh V, et al. Prophylaxis of radiation-induced nausea and vomiting: a systematic review and meta-analysis of randomized controlled trials. Ann Palliat Med. 2017;6(2):104-117. doi:10.21037/apm.2016.12.01

It is easy to stress over your baby that is crying a lot. Today I have A LOT of tips to help you through this rough phase.  Mama Natural Resource Other Episodes on Nursing Your baby from ME: Nursing Crash Course for First Time Moms Dealing with Emotional Ups and Down of Nursing a baby 5 tips for Success in Nursing Your Baby Breast Feeding to Lose Weight Eat, Wake, Sleep Cycle I use with my babies Works with Nursing or Breastfed babies **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

Close your eyes and repeat after me: "Less Pharma, More Karma"... In this fascinating interview, Dr. Jeni Noerenberg -- anesthesiologist AND integrative medicine physician -- takes a couple of noobs like Amit and Jeff and explains how techniques like noetic medicine, acupuncture, guided imagery, aromatherapy, nutrition, clinical hypnosis (and more!) are being used in the perioperative space to reduce anxiety, decrease anesthetic and opioid requirement, reduce nausea and pain, and improve other important patient outcomes. We learned a TON and Jeni left us inspired to learn more. Oh, and If you don't hear from us for a while, it just means we're not back from our shamanic journey yet.    Join us each month for another sassy conversation about anesthesiology, emergency medicine, critical care, POCUS, pain medicine, ultrasound guided nerve blocks, acute pain, and perioperative care!    Links:

I'm joined this week by writer and journalist Ilya Gridneff, whose career has taken him from Sydney to South Sudan and now to the Financial Times bureau in Canada. We talk about his first work of fiction, Your Name Here, co-authored with the brilliant Helen DeWitt — a wild, experimental novel with a long, unusual history. We also dive into the ideas and books that shaped him. If you enjoy the episode, please leave a review and follow @litwithcharles.Ilya Gridneff's four books were:2666, by Roberto Bolaño (2004)A Confederacy of Dunces, by John Kennedy Toole (1980)Nausea, by Jean-Paul Sartre (1938)Post Office, by Charles Bukowski (1971)

Nursing a baby is tough, but hang in there mama, the health benefits to you and baby are so worth it!  Dealing with Mom Guilt over Not Nursing Your baby Mama Natural Resource Other Episodes on Nursing Your baby from ME: Nursing Crash Course for First Time Moms Dealing with Emotional Ups and Down of Nursing a baby 5 tips for Success in Nursing Your Baby Breast Feeding to Lose Weight Eat, Wake, Sleep Cycle I use with my babies Works with Nursing or Breastfed babies **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy  

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:   Michelle: Hi Dr. Cabral, I started the para Support protocol this morning. I had 16 ounces of warm, lemon & hydrogen water upon waking and a half hour later took 2 of the Proteolytic enzymes on an empty stomach and about a half hour later I drank a cup of coffee with a teaspoon on ghee (my regular routine water first and coffee 20 min later). Shortly, there after I got extremely nauseous over the next several hours. I'm in overall good health and have taken many supple     Adam: Hey Dr. Cabral, I am 15 years old and weigh 160 pounds. I am 5ft 10 and a half and I have been working out for 3 years and have always tried to have a healthy lifestyle. I have recently been interested in taking supplements to support muscle building and overall health. What supplements, vitamins, and minerals do you recommend for someone of my age? Thank you for all that you do, God Bless.                             Taruna: I have been diagnosed with oral lichen planus for 5 years now. I have been on anti inflammatory diet but keep getting flares. Using hydroxychloroquine now, and steroids on and off for flare. Want to get your opinion                                    Tricia: Hi Dr Cabral, I just listened to your podcast this morning with Dr. Axe and Jordan Rubin. I enjoyed it thoroughly and did purchase the book. The one thing they mentioned that I do wrong is I love shellfish. I live in MD so I do have crabs but not frequently. In general I do eat shrimp once a week and scallops once or twice a week. Can you give me your thoughts on if we need to remove scallops? I read they aren't scavengers. I do your quarterly detox. Would you recommend I do your parasite protocol and how often? Interested in your opinion and advice how to offset the toxins from shellfish. I can't give it up totally. Thank you!                                                                                                                                                          Kai: Hello! Thank you for all you do. I am currently finishing up my IHP Level 2 and I'm excited to help people! Im 3 months postpartum and dealing with Hidradenitis Suppurativa (HS). It's a bummer to say the least. I eat organic, lots of veggies, pasture-raised beef etc. I do occasional dairy and sourdough. I also love the Equilife DNS! I'd like to do a detox as soon as I'm done breastfeeding. What test would you reccomend to figure out whats going on with the HS- please note I am a bit on a budget! Thank you!         Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3578 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Baby blues and the fluctuations of having a new on in the home and to care for can be very difficult and trying. Listen today for some tips on how to help combat these annoying negative emotions.  Noise Maker I have Mama Natural Week 2 Eat, Wake, Sleep Cycle I use with my babies **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy

Singer-songwriter Sam Milton previews his new album, Nausea and visual artist Claire Rosen discusses her extraordinary new book, Birds Of A Feather. Plus Lissa Warren talks books.

This component changed me and my motherhood in all good ways and it can change yours too! SO worth it to implement!    Email me at: positivityinpregnancy@gmail.com **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: Positiveinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Success in Second Trimester INTIMACY Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy Intimacy in the First Trimester Episode YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy

Upper Gut Issues: Root Causes of Bloating, Nausea & Stomach Pain | Podcast #466

You have been SO excited to get your baby here and now that they are here, you might be feeling overwhelmed and emotional. It is ok mama! You can do this! Join in for tips on getting through that first week postpartum!  Mama Natural Baby Week 1 **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy

Hey, Heal Squad! Have you ever wondered how acupuncture really works, or if those tiny needles (or even just pressure points!) can really heal things like vertigo, anxiety, or chronic pain? This week, Maria sits down with her personal acupuncturist, Anthony DiSalvo, a California Board-Certified Traditional Chinese Medicine practitioner to break it all down. Anthony explains all the secrets of what's really happening when you stimulate certain points on the body and why you don't even need needles to start feeling better. (Yep, he walks Maria through real-time acupressure points for vertigo, stress, and even digestion!) PLUS, they dive into the ancient wisdom of Traditional Chinese Medicine, how it views energy, emotions, and the body's natural ability to heal, and why modern medicine may be missing the bigger picture. You'll learn why balance is everything, how to move “stuck” energy, and how simple touch and breath can reset your entire system. This conversation will open your mind (and your meridians). Tune in!!  HEALERS & HEAL-LINERS:  Acupressure can be just as powerful as acupuncture. You don't always need needles to heal, using simple pressure points throughout the day can move stuck energy, ease pain, and calm your nervous system naturally. Your breath directs your body's energy. When you breathe intentionally into areas that feel tense or uncomfortable, you're literally telling your body where to send healing and blood flow Balance is the foundation of true health. Traditional Chinese Medicine teaches that prevention is more powerful than treatment, so daily self-care and energy balancing keep your system strong long before illness shows up. -- HEAL SQUAD SOCIALS IG: https://www.instagram.com/healsquad/ TikTok: https://www.tiktok.com/@healsquadxmaria HEAL SQUAD RESOURCES: Heal Squad Website:https://www.healsquad.com/ Heal Squad x Patreon: https://www.patreon.com/HealSquad/membership Maria Menounos Website: https://www.mariamenounos.com My Curated Macy's Page: Shop My Macy's Storefront EMR-Tek Red Light: https://emr-tek.com/discount/Maria30 for 30% off Airbnb: https://www.airbnb.com/  Thrive Causemetics: https://thrivecausemetics.com/healsquad Get 20% OFF with this link!  Briotech: https://shopbriotech.com/ Use Code: HEALSQUAD for 20% off  GUEST RESOURCES: Instagram: https://www.instagram.com/tlcholisticlife/?hl=en  Website: https://www.yudayimedicine.com/about-anthony-disalvo You can check out his courses here! https://courses.yudayimedicine.com/tlc-holistic-life ABOUT MARIA MENOUNOS: Emmy Award-winning journalist, TV personality, actress, 2x NYT best-selling author, former pro-wrestler and brain tumor survivor, Maria Menounos' passion is to see others heal and to get better in all areas of life. ABOUT HEAL SQUAD x MARIA MENOUNOS: A daily digital talk-show that brings you the world's leading healers, experts, and celebrities to share groundbreaking secrets and tips to getting better in all areas of life. DISCLAIMER: This Podcast and all related content (published or distributed by or on behalf of Maria Menounos or http://Mariamenounos.com and http://healsquad.com) is for informational purposes only and may include information that is general in nature and that is not specific to you. Any information or opinions provided by guest experts or hosts featured within website or on Company's Podcast are their own; not those of Maria Menounos or the Company. Accordingly, Maria Menounos and the Company cannot be responsible for any results or consequences or actions you may take based on such information or opinions. This podcast is presented for exploratory purposes only. Published content is not intended to be used for preventing, diagnosing, or treating a specific illness. If you have, or suspect you may have, a health-care emergency, please contact a qualified health care professional for treatment.

I have only been a mom 12 years but I have found that the thing that makes the biggest difference in discipline so far is following through.  Email me at: positivityinpregnancy@gmail.com **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: Positiveinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Success in Second Trimester INTIMACY Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy Intimacy in the First Trimester Episode YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy

Welcome back to our ⭐ Best Of series — where we're sharing some of the most loved and listened-to episodes from the Natural Super Kids Podcast.In this Best Of episode, we're revisiting one of our most popular topics — parasites in children — specifically the two we see most often: Blastocystis hominis and Dientamoeba fragilis.These microscopic critters can cause a surprising range of symptoms in kids — from tummy aches to mood swings an,d are more common than most parents realise.Jess shares the signs to look out for, how kids can pick them up, and the Natural Super Kids approach to treating and preventing parasite infections naturally.In this episode, you'll learn:The most common symptoms of parasite infections in children - digestive, mood, and behavioural changes.Why some kids are more at risk (especially those on tank water).How parasites can affect mood, irritability, and concentration.Our holistic, naturopathic approach to testing, treatment, and prevention.The role of gut health and “terrain” in keeping parasites at bay.How we use antimicrobial herbs, probiotics, and prebiotics to support recovery.When to consider medical treatment or further investigation.Episode Links:Blog post: Holistic approach to treating worms in kidsBlog post: Low iron in children – How to boost their levelsResearch: Mental and behavioural effects of parasitic infectionsResearch: Intestinal parasites may be associated with later behavioural problems in internationally adopted childrenNeed support with testing or treatment?If you suspect parasites could be affecting your child's health, our online clinic can help.  Our qualified naturopaths and nutritionists can arrange testing, interpret results, and create a personalised treatment plan to support your child's recovery and overall gut health — all from the comfort of your home.Book an online appointment hereThis episode is proudly sponsored by my membership, the Natural Super Kids Klub. If you would like to become a member of the Klub to get more helpful resources to help you raise a happy and healthy family click here and pop your name on the waitlist. If you loved this episode, leave me a review! I would really appreciate it. Also, let me know your biggest takeaway from this episode by sending me a direct message on Instagram @naturalsuperkids or shoot me an email at jessica@naturalsuperkids.com.

I have had a c-section, a v-bac induction, epidural, and all natural birth. Birth is a big event that deserves you to give yourself grace with how ever you baby comes to this beautiful world.  Mama Natural Baby Week 1 **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy

There weren’t many surprises on election night. Mamdani’s victory could be trouble for the Democrats in the long run. Does Bruce Harrell have enough of a cushion to hang on? // Jason had to stay up way past his bedtime last night to do election coverage for CNN and almost threw up on live TV. // Transportation Secretary Sean Duffy announced there will be airspace restrictions due to the government shutdown.

Yes your baby is coming! Listen for things to watch for and ways to increase positivity the last of this pregnancy. Email me at: positivityinpregnancy@gmail.com Inducing Labor Meditation Pregnancy Affirmations for when it feels heavy Love Focused Pregnancy Affirmations References: Bridget Tyler Pregnancy Week Guide Mama Natural Pregnancy Week by Week Guide **Morning Sickness Mini Course for Mental Health (Formerly the Positive Pregnancy Program)**: This self-led video program, made to help foster positivity durning pregnancy. It is for women who have or do struggle with pregnancy and who want to have strong mental health during and specifically the first trimester of pregnancy during the nausea! This Mini Course will help you mentally navigate the hardships of the physical changes of pregnancy, especially that morning sickness phase. Direct link to Morning Sickness Mini Course for Mental Health Positivity in Pregnancy and Motherhood website: www.positivityinpregnancy.com Other Episodes you might like: Anxiety? Stressed in pregnancy? Podcast episode Strategies to Calm Fears and Worries in Pregnancy Episodes on Dealing with Nausea in the first trimester: Puking and Feeling Like I Can't Coping with Nausea in Pregnancy YouTube for Positivity in Pregnancy: https://www.youtube.com/@PregnancyisHardwithJosly-nd8wd Here is the Facebook Page for Pregnancy is hard: I have documented my journey of my fourth baby on this page and have other juicy and good tips for enjoying pregnancy better. https://www.facebook.com/pregnancyishard Here is the Pregnancy is Hard Support Group on Facebook: Let's offer support, help and fun for those in the trenches of pregnancy! https://www.facebook.com/groups/165102315544693 Instagram: @positivityinpregnancy    

Leyla Muedin, a registered dietitian nutritionist, discusses the gastrointestinal (GI) side effects commonly experienced by patients using GLP-1 medications such as Ozempic and Rybelsus. Leyla introduces a nutraceutical called Digexin, created by N-X-T-U-S-A, which has shown promise in mitigating these side effects and improving overall well-being. The episode highlights the need for patients to prioritize animal protein intake and incorporate strength training to maintain muscle mass, especially when taking GLP-1 medications. Leyla emphasizes the importance of developing healthy habits and lifestyle changes to sustain weight loss after discontinuing these drugs.

Hydration Myths & Facts: Why Drinking Ice Water May Not Be Ideal. Nutritionist Leyla Muedin delves into the often-overlooked aspects of hydration, particularly focusing on the potential drawbacks of drinking ice-cold water. She explains the effects of excessively cold water on digestion and overall health, citing insights from experts like Dr. Harry Emrich. Leyla highlights why traditional practices and scientific evidence suggest that cool rather than cold water is more beneficial, especially during warm weather. Additionally, the episode offers practical advice on maintaining hydration through alternative methods, such as consuming water-rich fruits and vegetables, and the potential hazards of certain beverages like hot caffeinated drinks and alcohol during heat waves.

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