Podcasts about palladin

This week, we chat with Chef Daniel Holzman, who owns Danny Boy's Famous Original, a two-location operation in Los Angeles, California. We spoke with Daniel a few days before the catastrophic wildfires broke out in LA. So, our conversation with Daniel focused on his career, the growth of Danny Boy's and what he has learned in the restaurant business. Danny Boy's locations are currently safe. We would like to recognize Danny Boy's, who has quickly provided sanctuary for those affected. Both pizzerias are feeding the community, firefighters and first responders. More background on Daniel: Daniel started his cooking career at the age of 15 at Le Bernardin in New York City and remained there for four years until (at the suggestion of chef Eric Ripert) he attended the CIA. He then accepted a position at the soon-to-open Palladin in New York City under chef Jean-Louis Palladin (and worked alongside Wylie Dufresne and Sam Mason, among others). He went on to begin what would ultimately become a 10-year culinary journey through some of the West Coast's finest restaurants, including The Campton Place, The Fifth Floor, Aqua and Jardinière.In 2010, he co-founded The Meatball Shop in New York City. The fast-casual mix-and-match menu of meatballs was an instant hit. Five more locations of The Meatball Shop opened in NYC in quick succession, and he also co-authored The Meatball Shop Cookbook, published in 2011.He moved to LA in 2019 to embark on a new passion -- pizza -- and opened Danny Boy's Famous Original, the slice joint of his childhood dreams, in 2021. Describing the years-long his years-long odyssey to perfect the New York-style slice: "As a classically trained chef, I approach pizza with reverence. Pizza isn't fast food; it's one of America's most important dishes. And to understand how to make it great, I deconstructed everything about it. I searched out masters across the country, learned the history, and sampled thousands of pies. I interrogated oven makers, traveled to tomato farms, tried grains from countless flour mills, and experimented with the perfect cheese blend."Since opening, he's received praise from LA Magazine for his "ultrawide, perfectly foldable, tangy-crusted slices [that] nail it"; LAist for being a "NY-style pizzeria that absolutely rips"; and Eater LA, which claimed "There may be no better New York-style slice spot in LA than Danny Boy's right now.” He just opened his second location of Danny Boy's this past summer, and has his sights set on a third.He's also the co-author (with Matt Rodbard) of Food IQ: 100 Questions, Answers, and Recipes to Raise Your Cooking Smarts, released in 2022. (Some of the questions they answer include: "Why does pasta always taste better in a restaurant?", "When is it okay to cook with frozen vegetables?", and "What is baker's math, and why is it the secret to perfect pastry every time?")Last but not least, he also co-hosts On the Line, a podcast during which he and co-host Chef Amanda Freitag interview culinary innovators.More on the LA WildfiresAmong the horrible devastation from the wildfires in Los Angeles, we know there were pizzerias have been lost. Our new Senior Editor Kate Lavin is reporting on the LA Wildfires and the Pizza Community, including local pizzerias directly assisting the efforts on the ground, as well as Slice Out Hunger, who is rallying pizzerias in a fundraising effort to provide emergency funds. Read Kate's s

After a long Hiatus, Dan is back inside the Fifth Dimension diving deep into the seventh episode of the 1985 Twilight Zone reboot.  The first segment, "Teacher's Aide" stars a Gargoyle possesed Adrienne Barbeau  taking revenge on her unruly students. In "Palladin of the Lost Hour" Harlan Ellison spins a tale that unites an unlikely father and son relationship.  Danny Kaye and Glynn Turman shine in this emotional two hander. 

Follow him Here: @chefholzman Daniel Holzman started cooking at the age of 15 at the elite Le Bernardin in New York City. Four years later, he attended The Culinary Institute of America on a full scholarship from the James Beard Foundation. Since then, he's worked at numerous acclaimed eateries including Palladin, Napa, The Campton Place, Aqua, Jardinière, and Axe. In 2010, Daniel co-created The Meatball Shop, dedicated to serving the best meatballs in the world, in New York City. He is the co-author of the best-selling The Meatball Shop Cookbook, published in 2011, and is the co-author of Food IQ: 100 Questions, Answers, and Recipes to Raise Your Cooking Smarts, released in 2022. Over the course of his culinary career, he has been featured in publications such as The New York Times, Saveur, GQ, People, and Food Network Magazine and has appeared on Selena + Chef, The Tonight Show, and Good Morning America, among others. He now owns and operates Danny Boy's Famous Original Pizza, the New York-style slice joint of his childhood dreams, in Los Angeles.www.dannyboysfamousoriginalpizza.com

In this episode of New Politics, we look at the big week in Canberra, highlighting the continuing issues that have dominated the headlines and the halls of Parliament. Firstly, we examine the incident involving Barnaby Joyce's public intoxication in Canberra, which reignites discussions on the standards of behaviour expected from public figures. Joyce's actions are not just a personal failing but a reflection of broader issues within the political landscape, including double standards, substance misuse within Parliament, and the leniency often afforded to certain politicians.We also discuss Senator Linda Reynolds' announcement of her departure from politics at the next election, raising questions about the commitment and effectiveness of politicians who are on their way out but still hold office.The then explore the passage of the “right to disconnect” legislation, designed to protect employees from work-related intrusions into their personal time. Despite its benefits, the opposition, led by Peter Dutton, signals a contentious political climate, with debates skewed by media portrayal and party politics. Adding to the controversy, allegations against Peter Dutton during his tenure as Home Affairs Minister are scrutinised. Accusations of misconduct involving contracts and audits raise serious concerns about accountability and oversight within government operations.A surprising development in Parliament saw the success of a motion by independent MP Andrew Wilkie, advocating for the end of the prosecution of Julian Assange—a decision met with resistance from the Coalition, highlighting the divisive nature of political support and opposition in Australia.Lastly, the episode covers the unexpected call for a snap election in Tasmania by Premier Jeremy Rockliff, prompted by governmental instability and pressing local issues. This move could signify a pivotal moment for the Liberal Party and for Tasmanian politics, addressing or exacerbating existing challenges in health, education, and housing.Join us as we unpack these developments, offering insights into the ramifications for Australian politics and the ongoing debates that shape the nation's future. #AUSPOL #assangeSong listing:‘Confessions Of A Window Cleaner', Ed Kuepper.‘Just Give 'Em Whiskey', Colourbox.‘Praise You', Fat Boy Slim.

By 1958, Norman Macdonnell was a radio veteran with thousands of broadcast hours under his belt. He'd been producing and directing Gunsmoke since 1952. Gunsmoke's radio show was one of the first to offer a more-accurate portrayal of events and relationships from the Western era, as writer John Meston remembered. MacDonnell also directed the critically acclaimed Fort Laramie in 1956, but unlike with Gunsmoke, Fort Laramie was never able to secure national sponsorship. For more info on that series, tune into Breaking Walls episode 114. Frontier Gentleman ran into the same issues. The show was superb, but thanks to Television, there was no national advertiser appeal. So, when CBS canceled Frontier Gentleman they did so with another western in mind. Have Gun, Will Travel was in the midst of a successful second-TV season starring Dick Boone. Its lead character, Paladin, was a gun for hire based out of a posh San Francisco hotel. He advertised his services with a card that featured the series' title words. CBS felt the crossover appeal could attract national advertising dollars. Norman MacDonnell was given the task of directing the show. On November 8th, 1958, Macdonnell conducted three tests for the lead. Harry Bartell, Vic Perrin, and John Dehner all auditioned. They delivered the opening lines from what would become the debut episode. This is Mr. Bartell's. John Dehner would ultimately win the role.

Daniel started his cooking career at the age of 15 at Le Bernardin in New York City and remained there for 4 years until, at the suggestion of chef Eric Ripert, he attended the Culinary Institute of America with a full scholarship from the James Beard Foundation. Daniel's culinary journey has led him through some of the country's finest restaurants including Palladin, Napa, The Campton Place, Aqua, Jardinière, and Axe. In 2010, Daniel returned to his hometown of New York City to team up with his childhood friend Michael Chernow and debut The Meatball Shop on New York City's Lower East Side. This episode is brought to you by Authors Unite. Authors Unite provides you with all the resources you need to become a successful author. You can learn more about Authors Unite here: https://authorsunite.com/​​​​​​​​ Make sure to subscribe so you don't miss out on my future videos. --- Support this podcast: https://anchor.fm/authorsunite/support

In this adventure DM Vince sits down with Steven, who plays Seran the Palladin, and explored what happened to him while the group was out and about doing their own...

In this adventure DM Vince sits down with Steven, who plays Seran the Palladin, and explored what happened to him while the group was out and about doing their own...

We're here to let you know that Archie Andrews is canonically average at sex, mija. We were surprised, too. Trigger warnings: police violence, torture, child abuse, assault, su*cide --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/endgameriverdalepodcast/message

"We're going into these deals with the intent of partnering with Founders, that they're going to continue to be involved, and the last thing we want or need is for them to be surprised or disappointed with something along the way," states Rob Fioretti, Managing Director of Palladin Consumer Retail Partners. Rob has been in the private equity space for more than 25 years and in this chat with Pete, he provides extremely valuable information on what Palladin looks for in companies as well as the benefits of partnering with institutional partners versus using personal capital. He and Pete shed important light on the "business" of raising capital, why a firm may say no, some "behind the scenes" thoughts on valuations, what questions to ask before deciding to partner with a venture capital or private equity firm, the return of the studio model, and more!

The group battles Timulta, the Undead Palladin

The group reaches the final chamber of the castle and discovers the fate of the Palladin

Jean-Louis Palladin, who came to the United States from France in 1979, was one of the most talented and influential chefs of his generation. From his base in Washington, DC, Palladin, who died much too young in 2001 at age 55, helped forge a network of farmers and purveyors along the Eastern Seaboard, brought an unparalleled artistry and innate gift for improvisation to his cooking, wrote one of the first "coffee table" chef cookbooks, and left his mark on a generation of young Americans, inspiring such then-aspiring chefs as Anthony Bourdain and Thomas Keller.During a recent tribute dinner at the Watergate Hotel, Andrew sat down with a number of chefs who knew Palladin well: His contemporary and fellow immigrant French chef Jacques Pépin, three chefs who supported him at Jean-Louis at the Watergate--Larbi Dahrouch, Jimmy Sneed, and Jamie Stachowski--and chef of the Watergate's current showcase restaurant Kingbird, Sébastien Giannini.All of that, plus a bonus conversation with Jacques Pépin about how his hobby of  painting parallels his life in the kitchen.***EPISODE GUIDE***0:00 - 7:15 - Intro7:15 - 27:07 Segment 127:08 - 30:42 Mid-Show Break/Housekeeping Notes30:43 - end Segment 2***LINKS***Andrew Talks to Chefs official siteJean-Louis Palladin NY Times obituaryJean-Louis Palladin's book Cooking with the SeasonsJimmy Sneed's blog Product, Passion and SaltKingbird Restaurant at the Watergate

Kat and Greg are back for Season 2! This week we talk about Kat’s big break; George Pellophile; Climate change my mind; Cormac McMichael’s trainwreck in the sky; your Palladin and my Palladin, corruption; Hello Mathais; Morrison Arena Spectacular; bit of a Downer at the Bowlo and Democratic primaries feeling the Bern.

Our Moderator Libby gives hard-hitting stories of food in the news to our panelists and they discuss their attitudes and opinions in our Weekly Baste Segment. This week we discuss public displays of affection at restaurants, Bob Dylan's spirits company, future of school lunch, bologna and ketchup, the death of the New York coffee shop and meatballs of course! The Maillard Reaction Segment opens the floor for each panelist to give an opinion about a question that is relevant to the current week. The show is rounded out by our special guest, Daniel Holzman, co-owner of The Meatball Shop. Daniel's culinary journey has led him through some of the country's finest restaurants including Palladin, Napa, The Campton Place, Aqua, Jardinière and Axe. In 2010, Daniel returned to his hometown of New York City to team up with his childhood friend Michael Chernow and debut The Meatball Shop on New York City's Lower East Side. The mix-and-match menu of meatballs, served in a warm and convivial environment, was an instant hit. Five more locations of The Meatball Shop—in Williamsburg, the West Village, Chelsea, the Upper East Side and the Hell's Kitchen—opened in quick succession — and now Washington DC! The Main Course O.G. is powered by Simplecast

Laura Richards and Rachel Horman, award winning lawyer and Chair of Paladin National Stalking Advocacy Service, take a deep dive into the subject of stalking.Laura and Rachel discuss many cases including the five year stalking campaign waged on Helen Pearson which escalated to attempted murder, the case of Justene Reece and Dr Alison Hewitt who was stalked by a narcissistic psychopath and narrowly survived. Many of our listeners have written in with questions about what to do if you are being stalked and we have responded. This is a special episode to mark National Stalking Awareness Week in the UK.#NSAW2018#KnowTheLaw#UseTheLaw#Stalking#ReportingStalking Rachel Horman BiographyRachel Horman is a Solicitor and Head of the Domestic Abuse, Stalking and Forced Marriage Department at Watson Ramsbottom Ltd. With over 20 years experience Rachel is also the Chair of the charity Paladin, the National Stalking Advocacy Service Rachel regularly advises clients on how to increase the chances of obtaining a successful prosecution for stalking as well as advising in relation to civil options.She was highly commended in the Female Lawyer of the Year Category at the Law Society Excellence Awards 2016, won the Eva Business Award 2016, the Jordans Family Law Partner of the Year Award in 2014 and the National Family Legal Aid Lawyer of the Year Award in 2012 as recognition of her work in these areas.Rachel writes a poplar blog rachelhorman.co.uk where she comments on new developments or gaps in the law around Domestic Abuse, Stalking and Honour Based Violence.Please include (same as Clive pod)6 Golden Rules If You Are Being Stalked R - report it to police. Stalking is a crime. Tell people what's happening to you.E - evidence collection. Save and retain all evidence.P - practical advice from experts like Paladin and the National Stalking Helpline. O - overview of what's going on. Keep a diary with the time, date, stamp of the behaviour.R - risk screening questions. Anderson 12 S-DASH questions.T - Trust your instinct. Www.paladinservice.co.uk@paladinserviceAdvice for Victims and Stalking Lawhttps://paladinservice.co.uk/advice-for-victims/DV La Reform and Coercive Control Guidance https://paladinservice.co.uk/harassment-legislation/domestic-violence-campaign/HMIC/CPS Inspection Report in to the PÓlice and Crown Prosecution Response to Stalking https://www.justiceinspectorates.gov.uk/hmicfrs/publications/living-in-fear-the-police-and-cps-response-to-harassment-and-stalking/Petition for Serial Stalkers Sign the petition for serial stalkers and domestic violence perpetrators to be included on the sex offenders registerhttps://paladinservice.co.uk/serial-perpetrator-register-and-order/Alison Hewitt’s Book- Stalked https://www.amazon.co.uk/Stalked-dangerous-predator-terrifying-story-ebook/dp/B00LB89SI0Please visit watsonramsbottom.com and paladinservice.co.uk

Today Jon talks with Ed Hubbard, Futurist, Palladin and First Elder Emeritus of the Correllian Nativist Tradition of Wicca, and Founder of Nature's Little Recyclers in Chicago, about the transformative power and spiritual application of technology and cyberspace

Today Jon talks with Ed Hubbard, Futurist, Palladin and First Elder Emeritus of the Correllian Nativist Tradition of Wicca, and Founder of Nature's Little Recyclers in Chicago, about the transformative power and spiritual application of technology and cyberspace

This episode we go to a future with pirates! There always has to be at least one pirate episode per season. This time it’s pharmaceutical pirates.     This episode was inspired by a new book by Annalee Newitz called Autonomous. It’s very good and you should read it. I am not being paid to say that, I just really like the book.     Autonomous tells the story of two main characters: Jack the pharmaceutical pirate, and Palladin the bot that is trying to hunt her down. A few cool links related to Autonomous:    How to Write a Novel Set More Than 125 Years in the Future  Robots need civil rights, too  Sword and Laser podcast #306 - Indentured Robotude w/ Annalee Newitz  Pirates and Robots Square Off Over Drugs in Annalee Newitz’s Debut Novel  In A Future Ruled By Big Pharma, A Robot Tentatively Explores Freedom — And Sex: 'Autonomous'    For our episode, we focused on the pharmaceutical piracy part of the book. And to talk to us about the nitty gritty of how pharmaceuticals are made, and how they’re protected by patents, I talked to Jason Kahana, the founder and president of a small biotech company called Integrity Biosolutions, and Charles Duan, the director of the Patent Reform Project at Public Knowledge. [Full disclosure: my father and Jason know each other and have worked together in the past.]    These Aren’t the Patent Remedies You’re Looking For (No, Really)  Teva Pharmaceuticals Antitrust Settlement is a Win for Competition  Martin Shkreli Is Big Pharma’s Biggest A**hole  Drug C.E.O. Martin Shkreli Arrested on Fraud Charges  Yusuf Hamied, generic drugs boss  The Treasure of Mumbai   Pharmaceutical deformulation  The Role of Reverse Engineering in the Development of Generic Formulations  The Impact of the US Food and Drug Administration Chlorofluorocarbon Ban on Out-of-pocket Costs and Use of Albuterol Inhalers Among Individuals With Asthma  Do Patents Disclose Useful Information?   We Are Definitely Against Indefiniteness in Patents    Flash Forward is produced by me, Rose Eveleth. The intro music is by Asura and the outtro and ad-break music is by Hussalonia. The pirate music from the intro is by Nerve Damage. The future voices this episode were played by Tamara Krinsky, Brent Rose and Stephen Granade. The episode art is by Matt Lubchansky.     If you want to suggest a future we should take on, send us a note on Twitter, Facebook or by email at info@flashforwardpod.com. We love hearing your ideas! And if you think you’ve spotted one of the little references I’ve hidden in the episode, email us there too. If you’re right, I’ll send you something cool.     And if you want to support the show, there are a few ways you can do that too! We have a Patreon page, where you can donate to the show. But if that’s not in the cards for you, you can head to iTunes and leave us a nice review or just tell your friends about us. Those things really do help.     That’s all for this future, come back next month and we’ll travel to a new one. Learn more about your ad choices. Visit megaphone.fm/adchoices

Good afternoon everyone and welcome to another edition of The Avid Reader. Today our guest is Annalee Newitz author of her first novel Autonomous published September 19th by Tor (tomorrow). Annalee’s career started 15 years back in San Francisco at the Guardian. Later she worked at Wired and then founded the super cool io9 at Gawker. She edited io9 for 7 years then became the editor in chief at Gizmodo. Since last year she has been an editor at Ars Technica. She’s ben published in the New Yorker, The Washington Post The Times The Atlantic and many other publications. She also writes about movies, TV and books in the sci-fi fantasy genre. Which ties in nicely wit this her first venture into novel writing with Autonomous. Autonomous is about free will, love, corporate greed and deceit and loyalty. It follows the path of Jack (Judith) Chen, a modern day pirate who reverse engineers drugs and supplies them to the market in spite of the inherent but ill-gotten rights of major drug companies with semi-familiar names. Hot on Jack’s trail are two corporate cops, one human and one robotic, Eliasz (Elias) and Palladin. Who have their own unusual and unique relationship with each other. Jack seeks help along the way and finds it from some likely and unlikely sources. But the high concept that runs through the book is this concept of autonomy and what it means. And we can talk about that a little today.

Good afternoon everyone and welcome to another edition of The Avid Reader. Today our guest is Annalee Newitz author of her first novel Autonomous published September 19th by Tor (tomorrow). Annalee’s career started 15 years back in San Francisco at the Guardian. Later she worked at Wired and then founded the super cool io9 at Gawker. She edited io9 for 7 years then became the editor in chief at Gizmodo. Since last year she has been an editor at Ars Technica. She’s ben published in the New Yorker, The Washington Post The Times The Atlantic and many other publications. She also writes about movies, TV and books in the sci-fi fantasy genre. Which ties in nicely wit this her first venture into novel writing with Autonomous. Autonomous is about free will, love, corporate greed and deceit and loyalty. It follows the path of Jack (Judith) Chen, a modern day pirate who reverse engineers drugs and supplies them to the market in spite of the inherent but ill-gotten rights of major drug companies with semi-familiar names. Hot on Jack’s trail are two corporate cops, one human and one robotic, Eliasz (Elias) and Palladin. Who have their own unusual and unique relationship with each other. Jack seeks help along the way and finds it from some likely and unlikely sources. But the high concept that runs through the book is this concept of autonomy and what it means. And we can talk about that a little today.

Our experts Jim Clemente and Laura Richards respond to listener questions including how to become a profiler as well as expanding upon decision making when analyzing cases.

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The extracellular matrix (ECM) provides the structural frame for the development of tissues and organs. The ECM is bound by numerous membranous matrix-adhesion molecules and thereby triggers intracellular signals that control various cellular functions such as survival, polarity, proliferation and differentiation. Integrins represent an important family of ECM adhesion molecules which link the ECM with the intracellular actin-cytoskeleton. Integrin mediated adhesion structures also serve as important signaling platforms, although the integrin itself does not harbors any catalytic domains. Therefore integrin signaling depends on the recruitment of a number of cytoplasmic proteins that directly or indirectly bind to the short cytoplasmic integrin tails. During my PhD thesis I worked on three of these molecules, ILK, Kindlins and Palladin, and used the mouse as a model system to address their in vivo function. First, I investigated the role of integrin-linked kinase (ILK) in skeletal muscle. Loss of ILK expression in mice leads to peri-implantation lethality due to a cell polarization defect of the early embryo and abnormal actin accumulations. Studies in Caenorhabditis elegans and Drosophila melanogaster revealed an essential function for ILK in the attachment of actin filaments to the membrane of muscle cells and lack of ILK expression results in early lethality during embryogenesis. We generated mice with a skeletal muscle-restricted deletion of ILK that developed a mild, but progressive muscular dystrophy. This phenotype is predominantly restricted to myotendinous junctions (MTJs). Ultrastructural analyses showed muscle cell detachment from the basement membranes, and an accumulation of extracellular matrix. Endurance exercise training enhances the defect leading to disturbed subsarcolemmal myofiber architecture and an abrogation of the phosphorylation of Ser473 as well as Thr308 of protein kinase B (PKB)/Akt. The reduction in PKB/Akt activation is accompanied by an impaired insulin-like growth factor 1 receptor (IGF-1R) activation. Second, I studied the expression and in vivo function of a further integrin- and actin- associated protein, palladin. Palladin belongs to the palladin/myotilin/myopalladin protein family. Palladin represents a phosphoprotein which plays an important role in cell adhesion and motility. Initially, I characterized the gene structure and the expression pattern of palladin. The palladin gene spans about 400 kb, with 25 exons and 3 alternative promoters resulting in at least three different isoforms (200 kDa, 140 kDa and 90-92 kDa) in mice. Using RT-PCR and in situ hybridizations of embryonic and adult tissues, I could show that the 200kDa isoform is predominantly expressed in heart and skeletal muscle. In contrast, the 140kDa isoform is expressed in various tissues and represents the major palladin isoform of the brain. The 90-92 kDa isoform is almost ubiquitously expressed with highest levels in tissues rich in smooth muscle, like bladder, uterus, small intestine and colon. The expression of the 200kDa isoform was characterized in more detail with a polyclonal antibody showing that this isoform localizes to the Z-discs of heart and skeletal muscle cells. In vitro differentiation experiments with a mouse myoblast cell line revealed an induction of the 200kDa isoform during myoblast fusion and differentiation suggesting that the biggest palladin isoform may serve as a molecular scaffold during myogenesis. Third, I specifically inactivated the largest palladin isoform in mice. Lack of the 200 kDa palladin isoform has no impact on the development, viability and fertility of mice. However ultrastructural analyses by transmission electron microscopy (TEM) showed a mild cardiac myopathy due to disintegration of myofibrils. In collaboration with the group of Olli Carpén, we generated palladin 200 kDa isoform/ myotilin double knockout mice. Myotilin is also expressed in heart and skeletal muscle. Ablation of both myotilin and palladin 200 kDa isoform in mouse revealed in addition to the mild cardiac myopathy a structural and functional impairment of skeletal muscle. Finally, I was also involved in the characterization of the expression and subcellular localization of a novel family of integrin associated proteins: the Kindlins. The Kindlin family consists of three members, Kindlin-1, -2 and -3. Mutations in Kindlin-1 cause a human disease, called Kindler Syndrome, which represents a skin blistering disease affecting the actin cytoskeleton of basal keratinocytes. Kindlin gene expression was first analyzed at the mRNA level by RT-PCR and Northern Blot studies. In situ hybridizations showed that Kindlin-1 is preferentially expressed in epithelia. Kindlin-2 is expressed in all tissues with highest levels in striated and smooth muscle cells. While both localize to integrin-mediated adhesion sites in cultured keratinocytes Kindlin-2, but not Kindlin-1, colocalizes with E-cadherin to cell-cell contacts in differentiated keratinocytes. In contrast, Kindlin-3 expression is restricted to hematopoietic cells. Using a Kindlin-3-specific antiserum and an EGFP-tagged Kindlin-3 construct, we could show that Kindlin-3 is present in podosomes, which are specialized adhesion structures of hematopoietic cells.