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Have you ever wondered how far back modern skin-care recipes can be traced? It turns out, pretty far! Join Matilda and guest Katie Chin-Quee in the second part of their discussion all about ancient skin care. This episode, Katie shares some of the experimental archaeology that she has conducted with different ancient recipes, and why some ingredients are best left in the past! Transcripts For rough transcripts of this episode go to https://www.archpodnet.com/teabreak/54 Links Katie's post on her experiment Katie's LinkTree Article on honey and skin care The Scent of Ancient Greco-Roman Sculpture (article) The Ebers Papyrus translated Text Ovid on Cosmetics by Marguerite Johnson The rise of the cosmetic industry in ancient China: Insights from a 2700-year-old face cream (article) American Girl Dolls Some other interesting reads suggested by Katie: Doménech-Carbó, M.T. et al. (2012) “Characterization of prehispanic cosmetics found in a burial of the ancient city of Teotihuacan (Mexico),” Journal of archaeological science, 39(4), pp. 1043–1062. Cilione, M., Cavarra, B. and Gazzaniga, V. (2023) “Once again on the Empress Zoe: Women, dermatology, cosmetics, and materia medica (medical matter) in the ancient world,” Journal of cosmetic dermatology, 22(2), pp. 555–560. Ursin, F., Borelli, C. and Steger, F. (2020) “Dermatology in Ancient Rome: Medical ingredients in Ovid's ‘Remedies for female faces,'” Journal of Cosmetic Dermatology, 19(6), pp. 1388–1394. Contact the Host Email: matilda@thearchaeologiststeacup.com https://www.thearchaeologiststeacup.com insta: @the_archaeologists_teacup fb: /TheArchaeologistsTeacup twitter: @ArchaeoTeacup ArchPodNet APN Website: https://www.archpodnet.com APN on Facebook: https://www.facebook.com/archpodnet APN on Twitter: https://www.twitter.com/archpodnet APN on Instagram: https://www.instagram.com/archpodnet APN Shop Affiliates Motion Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Have you ever wondered how far back modern skin-care recipes can be traced? It turns out, pretty far! Join Matilda and guest Katie Chin-Quee in the second part of their discussion all about ancient skin care. This episode, Katie shares some of the experimental archaeology that she has conducted with different ancient recipes, and why some ingredients are best left in the past! Transcripts For rough transcripts of this episode go to https://www.archpodnet.com/teabreak/54 Links Katie's post on her experiment Katie's LinkTree Article on honey and skin care The Scent of Ancient Greco-Roman Sculpture (article) The Ebers Papyrus translated Text Ovid on Cosmetics by Marguerite Johnson The rise of the cosmetic industry in ancient China: Insights from a 2700-year-old face cream (article) American Girl Dolls Some other interesting reads suggested by Katie: Doménech-Carbó, M.T. et al. (2012) “Characterization of prehispanic cosmetics found in a burial of the ancient city of Teotihuacan (Mexico),” Journal of archaeological science, 39(4), pp. 1043–1062. Cilione, M., Cavarra, B. and Gazzaniga, V. (2023) “Once again on the Empress Zoe: Women, dermatology, cosmetics, and materia medica (medical matter) in the ancient world,” Journal of cosmetic dermatology, 22(2), pp. 555–560. Ursin, F., Borelli, C. and Steger, F. (2020) “Dermatology in Ancient Rome: Medical ingredients in Ovid's ‘Remedies for female faces,'” Journal of Cosmetic Dermatology, 19(6), pp. 1388–1394. Contact the Host Email: matilda@thearchaeologiststeacup.com https://www.thearchaeologiststeacup.com insta: @the_archaeologists_teacup fb: /TheArchaeologistsTeacup twitter: @ArchaeoTeacup ArchPodNet APN Website: https://www.archpodnet.com APN on Facebook: https://www.facebook.com/archpodnet APN on Twitter: https://www.twitter.com/archpodnet APN on Instagram: https://www.instagram.com/archpodnet APN Shop Affiliates Motion Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
CardioNerds Dr. Joseph Kassab, Dr. Mariana Garcia-Arango, and Dr. Christopher Mason explore the technological revolution of Coronary CT Angiography (CCTA) with expert faculty Dr. Michael Gallagher. The discussion details how CCTA has evolved into a frontline diagnostic and preventive tool, moving beyond simple anatomy to incorporate physiology via CT-FFR and biology through AI-driven plaque quantification. The episode reviews landmark evidence like the SCOT-HEART and PROMISE trials, the nuances of CAD-RADS 2.0 reporting, and the emerging role of AI in monitoring treatment response and personalizing cardiovascular care. Critically, they also discuss some of the assumptions and limitations of these techniques. Stay tuned for a matching review article to be submitted to US Cardiology Review, the official Journal of CardioNerds. This episode was supported by an independent medical education grant from HeartFlow. All CardioNerds education is planned, produced, and reviewed solely by CardioNerds. Enjoy this Circulation Paths to Discovery article to learn more about the CardioNerds mission and journey. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscripts here. CardioNerds Multimodality Cardiovascular Imaging PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll Pearls Shift in Paradigm: CCTA is no longer just an anatomic test; with some key limitations, it can provide anatomy, physiology (CT-FFR), and plaque biology (AI-CPA) in a single non-invasive scan. The “Power of Zero” vs. Plaque: While a normal CCTA has a >95% negative predictive value, future MIs often arise from non-obstructive plaque that traditional stress tests might miss. CAD-RADS 2.0 Utility: The addition of plaque burden modifiers (P1–P4) is a “game changer,” allowing clinicians to identify high-risk patients who need aggressive lipid-lowering despite having only mild stenosis. CT-FFR as a Virtual Stress Test: CT-FFR uses computational fluid dynamics to simulate blood flow, potentially reducing unnecessary invasive catheterizations by approximately 61% without sacrificing safety. Seeing the Invisible: AI-based quantitative plaque analysis (QCPA) can identify “subvisual” plaque and low-attenuation (lipid-rich) components that are the primary drivers of acute coronary syndromes. Show Notes How has the role of CCTA changed compared to traditional functional testing? Historically, stress testing answered “is there ischemia today?”, which often reflects late-stage disease. CCTA identifies disease across the entire spectrum, asking “is there atherosclerosis and how much plaque is present?”. Landmark evidence: SCOT-HEART showed a 41% relative risk reduction in MI at 5 years attributed to intensified preventive therapies, and PROMISE showed CCTA was better at selecting patients who truly needed invasive angiography. Diagnostic CCTA imaging depends on the protocol, contrast timing, heart rate, heart rhythm, breathholding, scanner quality, and several patient factors (obesity, prior stents, heavy calcification, complex bypass anatomy, and motion artifact all may limit imaging). “CCTA is exceptional for the right patient, with the right scanner, and the right team.” What are the key modifiers introduced in CAD-RADS 2.0, and why do they matter? CAD-RADS 2.0 moved beyond stenosis severity to include plaque burden (P0 to P4), high-risk plaque (HRP) features, and the presence of ischemia based on CT-FFR. It serves as a clinical decision support tool: a patient with mild (25-49%) stenosis but “extensive” (P4) plaque burden is considered high risk and warrants aggressive risk factor modification. How is CT-FFR calculated, and when is it most useful in clinical practice? CT-FFR uses resting CCTA data and computational fluid dynamics to create a 3D model of coronary flow during simulated maximal hyperemia. It is often used for intermediate lesions (40–90% stenosis) to predict if they are ischemia-producing, guiding the decision whether to proceed with invasive angiography. The assumptions necessary for this computational modeling may not apply well to patients with microvascular dysfunction, significant myocardial scar or prior infarction, or ventricular hypertrophy. Still, data indicate that CT-FFR performs similarly to PET in predicting hemodynamically significant lesions. CT-FFR performs well at the extremes (either clearly normal or clearly abnormal). Accuracy dips, however, in the intermediate range (~0.75-0.80), where decision-making is most critical. In this grey zone, additional factors can help guide the approach, including the amount of myocardium supplied, translesional gradient, and plaque features. CT-FFR has not been validated in distal segments, stented segments, heavily calcified coronary arteries, or in patients with severe aortic stenosis. Caution with CT-FFR should be utilized in very calcified coronary segments. What is AI-based quantitative plaque analysis (QCPA), and what metrics are ready for clinical use? This is potentially a paradigm shift, moving away from stenosis-centric thinking to a more disease burden and plaque biology focus. QCPA uses deep learning algorithms to automatically segment the vessel wall and quantify plaque volume in mm³. Ready for “prime time” metrics include: Total Plaque Volume (TPV), non-calcified plaque volume, and Low-Attenuation Plaque (LAP) burden. Can serial CCTA be used to monitor the effectiveness of medical therapies like statins? While not yet a routine guideline-driven practice, trials like PARADIGM and EVAPORATE show that therapies can stabilize plaque; notably, CCTA is better for monitoring than CAC scores, which can be misleading as statins often increase plaque calcification as part of the stabilization process. There are no randomized trials that serial CCTAs improve outcomes. Cost and radiation exposure will be notable limitations. Serial scan timing, scan acquisition and interpretation standardization would be key. Dr. Gallagher notes that we are moving toward a world in which plaque burden may become a “treatment biomarker,” similar to tumor burden in oncology. References 1. Coronary Computed Tomography Angiography From Clinical Uses to Emerging Technologies: JACC State-of-the-Art Review. Abdelrahman KM, Chen MY, Dey AK, et al. Journal of the American College of Cardiology. 2020;76(10):1226-1243. doi:10.1016/j.jacc.2020.06.076. 2. Non-Invasive Imaging in Coronary Syndromes: Recommendations of the European Association of Cardiovascular Imaging and the American Society of Echocardiography, in Collaboration With the American Society of Nuclear Cardiology, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance. Edvardsen T, Asch FM, Davidson B, et al. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 2022;35(4):329-354. doi:10.1016/j.echo.2021.12.012. 3. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Gulati M, Levy PD, Mukherjee D, et al. Journal of the American College of Cardiology. 2021;78(22):e187-e285. doi:10.1016/j.jacc.2021.07.053. 4. Contemporary, Non-Invasive Imaging Diagnosis of Chronic Coronary Artery Disease. van der Bijl P, Gulati M, Saraste A, et al. Lancet (London, England). 2025;406(10519):2577-2587. doi:10.1016/S0140-6736(25)01586-7. 5. State of the Art: Evaluation and Medical Management of Nonobstructive Coronary Artery Disease in Patients With Chest Pain: A Scientific Statement From the American Heart Association. Slipczuk L, Blankstein R, Bucciarelli-Ducci C, et al. Circulation. 2025;152(23):e443-e466. doi:10.1161/CIR.0000000000001394. 6. Diagnostic Performance of Fractional Flow Reserve Derived From Coronary CT Angiography: The ACCURATE-CT Study. Li C, Hu Y, Jiang J, et al. JACC. Cardiovascular Interventions. 2024;17(17):1980-1992. doi:10.1016/j.jcin.2024.06.027. 7. Clinical Outcomes Based on Coronary Computed Tomography-Derived Fractional Flow Reserve and Plaque Characterization. Sato Y, Motoyama S, Miyajima K, et al. JACC. Cardiovascular Imaging. 2024;17(3):284-297. doi:10.1016/j.jcmg.2023.07.013. 8. Clinical Use of Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve: Expert Consensus by an International Working Group. Tang CX, Leipsic JA, Nørgaard BL, et al. European Radiology. 2026;:10.1007/s00330-025-12313-6. doi:10.1007/s00330-025-12313-6. 9. Diagnostic accuracy of computed tomography–derived fractional flow reserve: a systematic review. Cook CM, Petraco R, Shun-Shin MJ, et al. JAMA Cardiol. 2017;2(7):803-810. Doi:10.1001/jamacardio.2017.1314 10. Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in suspected coronary artery disease: the NXT trial (Analysis of Coronary Blood Flow Using CT Angiography: Next Steps). Nørgaard BL, Leipsic J, Gaur S, et al. J Am Coll Cardiol. 2014;63(12):1145-1155. Doi:10.1016/j.jacc.2013.11.043 11. Comparison of coronary computed tomography angiography, fractional flow reserve, and perfusion imaging for ischemia diagnosis. Driessen RS, Danad I, Stuijfzand WJ, et al. J Am Coll Cardiol. 2019;73(2):161-173. Doi:10.1016/j.jacc.2018.10.056. 12. 1-year outcomes of FFRCT-guided care in patients with suspected coronary disease: the PLATFORM study. Douglas PS, De Bruyne B, Pontone G, et al. J Am Coll Cardiol. 2016;68(5):435-445. Doi:10.1016/j.jacc.2016.05.057. 13. Comparison of an initial risk-based testing strategy vs usual testing in stable symptomatic patients with suspected coronary artery disease: the PRECISE randomized clinical trial. Douglas PS, Nanna MG, Kelsey MD, et al; PRECISE Investigators. JAMA Cardiol. 2023;8(10):904-914. Doi:10.1001/jamacardio.2023.2595. 14. Diagnostic and clinical value of FFRCT in stable chest pain patients with extensive coronary calcification: the FACC study. Mickley H, Veien KT, Gerke O, et al. JACC Cardiovasc Imaging. 2022;15(6):1046-1058. doi:10.1016/j.jcmg.2021.12.010. 15. Low-Attenuation Noncalcified Plaque on Coronary Computed Tomography Angiography Predicts Myocardial Infarction: Results From the Multicenter SCOT-HEART Trial (Scottish Computed Tomography of the HEART). Williams MC, Kwiecinski J, Doris M, et al. Circulation. 2020;141(18):1452-1462. doi:10.1161/CIRCULATIONAHA.119.044720. 16. AI-Guided Quantitative Plaque Staging Predicts Long-Term Cardiovascular Outcomes in Patients at Risk for Atherosclerotic CVD. Nurmohamed NS, Bom MJ, Jukema RA, et al. JACC. Cardiovascular Imaging. 2024;17(3):269-280. doi:10.1016/j.jcmg.2023.05.020. 17. Interaction of AI-Enabled Quantitative Coronary Plaque Volumes on Coronary CT Angiography, FFRCT, and Clinical Outcomes: A Retrospective Analysis of the ADVANCE Registry. Dundas J, Leipsic J, Fairbairn T, et al. Circulation. Cardiovascular Imaging. 2024;17(3):e016143. doi:10.1161/CIRCIMAGING.123.016143. 18. Prognostic Value of AI-Based Quantitative Coronary CTA vs Human Reader-Based Visual Assessment: Results From the CONFIRM2 Registry. van Rosendael A, Nakanishi R, Bax JJ, et al. JACC. Cardiovascular Imaging. 2026;19(3):345-359. doi:10.1016/j.jcmg.2025.09.021.13. Pericoronary Adipose Tissue as a Marker of Cardiovascular Risk: JACC Review Topic of the Week. Tan N, Dey D, Marwick TH, Nerlekar N. Journal of the American College of Cardiology. 2023;81(9):913-923. doi:10.1016/j.jacc.2022.12.021. 19. Effect of Icosapent Ethyl on Progression of Coronary Atherosclerosis in Patients With Elevated Triglycerides on Statin Therapy: Final Results of the EVAPORATE Trial. Budoff MJ, Bhatt DL, Kinninger A, et al. European Heart Journal. 2020;41(40):3925-3932. doi:10.1093/eurheartj/ehaa652. 20. Coronary CT Angiography Evaluation With Artificial Intelligence for Individualized Medical Treatment of Atherosclerosis: A Consensus Statement From the QCI Study Group. Schulze K, Stantien AM, Williams MC, et al. Nature Reviews. Cardiology. 2026;23(2):100-115. doi:10.1038/s41569-025-01191-6.
The cannabis industry convinced the world it had a medicine before the science caught up. Now the science is here, and almost no one is paying attention. CBD is not a panacea. When Charlotte's Web opened hearts and minds, the messaging of what it could do ran years ahead of what the data could actually support. That gap created a backlash the legitimate medical thesis didn't deserve. What's left on the other side of the green rush is a near-complete forgetting of the reason this industry started in the first place. The medicine. Now the infrastructure to prove it is finally in place. Standardized genetics. Reproducible extraction. Full compound characterization. An FDA botanical drug pathway that has existed since 2016 that most investors have never heard of. Organic medicine versus synthetic single-molecule will be a real choice at the pharmacy counter sooner than most people expect. The foundational work is already here. This week we sit down with Joel Stanley and Dr. Marcel Bonn-Miller: Botanical drugs vs. supplements 6,000 compounds, one drug Novel compounds nobody has named yet Chapters 00:00 Why Medical Validation Remains a Challenge for Cannabis 00:12 The FDA Approval Process for Plant-Based Medicines 01:03 Historical Market Dynamics and Their Impact on Cannabis Perception 02:48 Removing the Veil: How Science Can Validate Cannabinoid Therapies 03:15 The Complexity of Plant Molecules and Real-World Evidence 06:20 Focus in Drug Development: The Case of Autism Spectrum Disorder 07:10 The Impact of Charlotte's Web and Media Hype 08:52 Balancing Hype and Reality in Cannabinoid Medicine 10:01 Legitimization of Cannabis Research in Academia 12:10 The Evolution of Cannabis Research and Acceptance 13:54 The Future of Botanical Medicine and Academic Research 16:15 The Long Road of Drug Development for Cannabis-Based Medicines 20:50 Introducing AJA-001: A Botanical Drug for Autism 22:44 Standardization and Characterization of Botanical Drugs 24:01 Partnerships and Funding in Botanical Drug Development 24:40 Challenges of Multi-Compound Botanical Drugs 27:28 Reproducibility and Quality Control in Botanical Manufacturing 29:06 FDA Pathways for Botanical Drugs and New Chemical Entities 34:29 Identifying and Characterizing Thousands of Plant Compounds 39:48 The Role of AI and Supercomputing in Drug Discovery 41:11 Balancing Exploration and Focus in Botanical Research 44:38 What the World Will Understand About Cannabinoids in 10 Years 47:24 The Promise of Botanical Medicine Over Single Molecule Drugs Guest Links: AJNA Biosciences Websitehttps://ajnabiosciences.com/ AJNA Biosciences LinkedInhttps://www.linkedin.com/company/ajna-biosciences/posts/?feedView=all AJNA Biosciences Instagram @ajnabiosciences Charlotte's Web Websitehttps://www.charlottesweb.com/ Charlotte's Web LinkedInhttps://www.linkedin.com/company/charlottesweb/posts/?feedView=all Charlotte's Web Instagram @charlotteswebcbd Joel Stanley LinkedInhttps://www.linkedin.com/in/joel-stanley-2885116b/ Joel Stanley Instagram @joel.stanley Dr. Marcel Bonn-Miller LinkedInhttps://www.linkedin.com/in/marcel-bonn-miller-897a581/ Our Links: Bryan Fields on Twitter Kellan Finney on Twitter The Dime on Twitter Extraction Teams: Want to cut costs and get more out of every run? Unlock hidden revenue by extracting more from the same input—with Newton Insights. At Eighth Revolution (8th Rev), we provide services from capital to cannabinoid and everything in between in the cannabinoid industry. The Dime is a top 5% most shared global podcast The Dime is a top 10 Cannabis Podcast The Dime has a New Website. Shhhh its not finished.
On this episode of Hyperspace Theories, Tricia Barr and B.J. Priester continue our discussion of the new Maul – Shadow Lord animated series. This time we focus on the writing and characterization of the principal characters, especially Maul and how his past and present informs his strategy for gradually guiding Devon Izara toward her choice to become his apprentice. Along the way we consider the connections between the titular character we see in Maul – Shadow Lord and his earlier incarnations in The Phantom Menace and The Clone Wars, and how those portrayals influence who Maul has become by his time on Janix. We also compare Maul's proposal to Ahsoka Tano during the Siege of Mandalore at the end of that war to his goals with Devon Izara in Shadow Lord. With Maul's future appearances in Solo: A Star Wars Story and Star Wars Rebels already established, we also speculate briefly on where the new characters from Maul – Shadow Lord may be headed in its second season. Rylee Lawson and Two-Boots believe that Brander Lawson was killed by stormtroopers in their escape, which may affect their choices in his absence, but the show provides a strong storytelling reason to think he isn't dead (yet). Devon's future is unknown, too, and the parallel with Ahsoka poses some interesting possibilities for her ultimate fate, as well. Related Links: Fangirls Going Rogue Episode 26.3 Maul – Shadow Lord Interviews and Review Fangirls Going Rogue Episode 26.5 Maul's Next Chapter House of R podcast (YouTube): The 'Star Wars: Maul—Shadow Lord' Season 1 Finale With Sam Witwer Social Media: Tricia Barr (@fangirlcantina) Instagram | Threads | Blue Sky B.J. Priester (@redpenoflex) Instagram | Threads | Blue Sky Fangirl Zone on Facebook
In this episode, take a step back from the hustle and bustle of daily life to practice a little bit of self care and join Matilda and her guest Katie Chin-Quee in this latest exploration of the archaeology of everyday things. Katie shares the many twists and turns of the path that led her to a career in archaeology, and how she became involved with the particular topic of ancient skin-care. Together, they chat about the issues with supposedly “feminine” research topics, and why branching out on digital platforms can be a great way to develop your science communication skills. Transcripts For rough transcripts of this episode go to https://www.archpodnet.com/teabreak/53 Links Some examples of cosmetic palettes Katie's LinkTree Katie's instagram Katie's post on experimental ancient skin care The Scent of Ancient Greco-Roman Sculpture (article) The Ebers Papyrus translated Text Ovid on Cosmetics by Marguerite Johnson The rise of the cosmetic industry in ancient China: Insights from a 2700-year-old face cream (article) American Girl Dolls Some other interesting reads suggested by Katie: Doménech-Carbó, M.T. et al. (2012) “Characterization of prehispanic cosmetics found in a burial of the ancient city of Teotihuacan (Mexico),” Journal of archaeological science, 39(4), pp. 1043–1062. Cilione, M., Cavarra, B. and Gazzaniga, V. (2023) “Once again on the Empress Zoe: Women, dermatology, cosmetics, and materia medica (medical matter) in the ancient world,” Journal of cosmetic dermatology, 22(2), pp. 555–560. Ursin, F., Borelli, C. and Steger, F. (2020) “Dermatology in Ancient Rome: Medical ingredients in Ovid's ‘Remedies for female faces,'” Journal of Cosmetic Dermatology, 19(6), pp. 1388–1394. Contact the Host Email: matilda@thearchaeologiststeacup.com https://www.thearchaeologiststeacup.com insta: @the_archaeologists_teacup fb: /TheArchaeologistsTeacup twitter: @ArchaeoTeacup ArchPodNet APN Website: https://www.archpodnet.com APN on Facebook: https://www.facebook.com/archpodnet APN on Twitter: https://www.twitter.com/archpodnet APN on Instagram: https://www.instagram.com/archpodnet APN Shop Affiliates Motion Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode, take a step back from the hustle and bustle of daily life to practice a little bit of self care and join Matilda and her guest Katie Chin-Quee in this latest exploration of the archaeology of everyday things. Katie shares the many twists and turns of the path that led her to a career in archaeology, and how she became involved with the particular topic of ancient skin-care. Together, they chat about the issues with supposedly “feminine” research topics, and why branching out on digital platforms can be a great way to develop your science communication skills. Transcripts For rough transcripts of this episode go to https://www.archpodnet.com/teabreak/53 Links Some examples of cosmetic palettes Katie's LinkTree Katie's instagram Katie's post on experimental ancient skin care The Scent of Ancient Greco-Roman Sculpture (article) The Ebers Papyrus translated Text Ovid on Cosmetics by Marguerite Johnson The rise of the cosmetic industry in ancient China: Insights from a 2700-year-old face cream (article) American Girl Dolls Some other interesting reads suggested by Katie: Doménech-Carbó, M.T. et al. (2012) “Characterization of prehispanic cosmetics found in a burial of the ancient city of Teotihuacan (Mexico),” Journal of archaeological science, 39(4), pp. 1043–1062. Cilione, M., Cavarra, B. and Gazzaniga, V. (2023) “Once again on the Empress Zoe: Women, dermatology, cosmetics, and materia medica (medical matter) in the ancient world,” Journal of cosmetic dermatology, 22(2), pp. 555–560. Ursin, F., Borelli, C. and Steger, F. (2020) “Dermatology in Ancient Rome: Medical ingredients in Ovid's ‘Remedies for female faces,'” Journal of Cosmetic Dermatology, 19(6), pp. 1388–1394. Contact the Host Email: matilda@thearchaeologiststeacup.com https://www.thearchaeologiststeacup.com insta: @the_archaeologists_teacup fb: /TheArchaeologistsTeacup twitter: @ArchaeoTeacup ArchPodNet APN Website: https://www.archpodnet.com APN on Facebook: https://www.facebook.com/archpodnet APN on Twitter: https://www.twitter.com/archpodnet APN on Instagram: https://www.instagram.com/archpodnet APN Shop Affiliates Motion Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Don't miss a touching interview with Rayanne Gonzalez from Signature Theatre's Helen Hayes nominated production of In the Heights.
A Third Assassination Attempt:This is the third attempted assassination against President Donald Trump, crediting the Secret Service and law enforcement for stopping the suspect. Attribution of Responsibility to Political Rhetoric:Violent acts are being fueled by inflammatory rhetoric from Democrats, left‑leaning media figures, and progressive commentators, who are normalizing or encouraging political violence. Focus on Specific Statements and Figures:Remarks by Democratic leaders, media personalities, and online commentators that are endorsing or joking about violence, using these examples to argue that such language has real‑world consequences. Characterization of the Suspect:The alleged attacker is described as ideologically motivated rather than mentally ill, portrayed as a “radicalized” individual influenced by left‑wing ideology, academic environments, and media narratives about Trump and Republicans. Praise of Trump’s Response:President Trump acted with restraint and leadership after the incident, calling for unity, peaceful resolution of differences, and respect for free speech, even while enduring hostile questioning from the media. Criticism of Media Conduct:Media outlets and journalists are irresponsibly repeating accusations from the attacker’s manifesto and reinforcing narratives that the speakers believe contribute to further radicalization. Broader Warning About Political Climate:Escalating rhetoric, ideological indoctrination, and tolerance of violent language are creating a dangerous environment where political figures and public events increasingly require heightened security. Please Hit Subscribe to this podcast Right Now. Also Please Subscribe to the 47 Morning Update with Ben Ferguson and The Ben Ferguson Show Podcast Wherever You get You're Podcasts. And don't forget to follow the show on Social Media so you never miss a moment! Thanks for Listening YouTube: https://www.youtube.com/@VerdictwithTedCruz/ Facebook: https://www.facebook.com/verdictwithtedcruz X: https://x.com/tedcruz X: https://x.com/benfergusonshowYouTube: https://www.youtube.com/@VerdictwithTedCruzSee omnystudio.com/listener for privacy information.
How is it April? The episodes have been so long lately it feels like it should be more than two months since the hiatus ended. As a countermeasure, the Nice Hosts have another set of roundtable topics to break up your week and retune the time dilation. Stephen tries hard not to talk about fighting games, Lydia ponders the nature of instructions, and everyone talks a lot more about Mario than they thought they would. 0:01:41Characterization Through MechanicsWe talked about characterization in Smash on a previous episode."I'm intrigued by big door."Lewis ChessmenWikipedia0:29:24Tutorials vs. InstructionsThe "tutorial" Lydia encountered at work that inspired this topic.
Support my work on Patreon- https://patreon.com/realdavejackson Discord, Socials and more- https://linktr.ee/talesfromthebacklog Join Dave and special guest Josh Galecki (Pixelated Playgrounds, Moonroof Studios) to take a long walk into the woods of Baby Steps. Developed by Bennett Foddy, Gabe Cuzillo and Maxi Boch and published by Devolver Digital, Baby Steps is an extremely unique game, one where its story of its failson protagonist meshes with its frustrating-yet-rewarding gameplay for a very rewarding and genuinely funny experience. Check out the podcast for more. Guest info: Josh Galecki (he/him) Check out Pixelated Playgrounds https://www.pixelatedplaygrounds.com/ Check out Josh's games on Steam https://store.steampowered.com/search/?developer=Moonroof%20Studios Check out more of Josh's games on itch https://joshuagalecki.itch.io/ TIMESTAMPS 0:00 Title Card 0:11 Introductions 5:42 Our Histories with Baby Steps 9:42 Top-Level Thoughts 15:11 Characterization of Nate 20:18 Walking Mechanics 26:56 Difficulty and World Design 40:19 Hating On Nate and Comedy 54:27 Visuals, Music and Sound 59:13 Who Should Play Baby Steps? 1:04:16 Pixelated Playgrounds and Moonroof Studios 1:08:40 Spoiler Wall & Patron Thank-Yous 1:10:17 Spoilers- Jim, The Manbreaker, Other Challenges 1:32:19 Spoilers- Let's Talk About Nate 1:42:28 Spoilers- Nate's Journey and Endings 1:55:43 Accomplishments vs Achievements 2:04:23 Guys...Where Are We? Sound clips in episode were captured in game. The Secret Lives of Games interview with Bennett Foddy & Gabe Cuzillo- https://eggplant.show/152-walking-over-it-with-gabe-cuzzillo-and-bennett-foddy-baby-steps Cover art by Jack Allen- find him at https://linktr.ee/JackAllenCaricatures
Moon Nahm, M.D., professor emeritus at UAB Department of Medicine and Director of the World Health Organization's Pneumococcal Serology Reference Laboratory at UAB, discusses his career in pneumococcal immunology. From uncovering the WU2 reference strain and other hidden serotypes to pioneering Multiplexed Opsono-Phagocytosis Assay (MOPA) to measure the functional activity of anti-pneumococcal antibodies, Nahm's contributions have facilitated development of advanced vaccines with broader protection and accessibility. Links for This Episode UAB Spotlight on Moon Nahm. Discovery and Characterization of Pneumococcal Serogroup 36 Capsule Subtypes, Serotypes 36A and 36B. Journal of Clinical Microbiology paper, March 27, 2003. A New Pneumococcal Capsule Type, 10D, is the 100th Serotype and Has a Large cpsFragment from an Oral Streptococcus. mBio, May 19, 2020. 50 years—and change. WashU Magazine. MTM Listener Survey
In this episode, Dr. Jasmine Barnes and Dr. Margaret Lowenstein sit down to discuss their new article Characterization of a Young Adult Sample Accessing Buprenorphine Via Telehealth in Philadelphia, PA featured in the January/February 2026 issue of the Journal of Addiction Medicine. Article Link: Characterization of a Young Adult Sample Accessing Buprenorphine Via Telehealth in Philadelphia, PA
Hey Voices from the Bench community! Jessica Love here, sending a shoutout from Utah! If you're passionate about creating natural, beautiful smiles—but want to simplify your workflow without sacrificing aesthetics—this is for you. I'm honored to be part of Ivoclar's development team introducing a powerful new stain and glaze system featuring Structure Paste, IPS e.max Ceram Art. Create stunning depth and lifelike color in as little as one firing. Let's continue to innovate, simplify, and create meaningful change—one smile at a time. When it comes to digital dentures, design is easy—manufacturing is where things get messy. That's why the Elevate Denture Solution brings it all together. Built by Roland DGSHAPE, Ivoclar, and FOLLOW-ME! Technology Group, it combines machine, materials, and CAM into one fully optimized workflow—so you get consistent, high-quality results without the guesswork. Want to simplify production and scale with confidence? Check it out at rollanddga.com/elevate. "Live" from the Ivoclar ballroom at Lab Day 2026, Elvis and Barb dives into conversations that perfectly capture what this industry is all about—innovation, relationships, and a whole lot of nerding out. We kick things off with Frederic Rapp, who went from growing up in his dad's basement lab in France to scaling it into one of the largest labs in Europe. After selling the business, he found his way back into the industry through innovation—helping labs unlock the gold mine sitting inside their own data with icortica. From dashboards to AI-driven insights and even voice-activated notes in the parking lot, it's all about working smarter, not harder… and maybe not looking like an idiot when you walk into a doctor's office. Then things shift to a great partnership with Casey Baldwin and Darin Lockaby, where we get into a seriously cool collaboration between Ivoclar and DESS. Think plug-and-play workflows that let labs mill their own abutments in-house—FDA compliant, streamlined, and actually simple. With margins tighter than ever, this kind of control over production isn't just nice… it's becoming necessary. From scaling labs to scaling data, from implants to AI, this episode is packed with insight, laughs, and a clear message: the labs that embrace technology (without losing the human touch) are the ones that are going to win. Join us at exocad Insights 2026, happening April 30–May 1, 2026, on the stunning island of Mallorca, Spain. This two-day event features powerhouse keynotes, hands-on workshops, live software demos, and top-tier industry showcases—all in one unforgettable setting. Barb and Elvis will be on site bringing you exclusive interviews, plus don't miss the Women in Dentistry Lunch, celebrating career growth, wellbeing, and the real stories shaping our profession. And of course, cap it all off with the legendary exoGlam Night under the stars. Tickets are limited. Visit exocad.com/insights-2026 and use code VFTBPalma15 for 15% off.Special Guests: Casey Baldwin, Darin Lockaby, and Frederic Rapp.
Dr. Francis Marchlinski highlights new research comparing high‑density electroanatomical mapping with cardiac MRI in non‑ischemic cardiomyopathy. He explains how omnipolar mapping more accurately reflects MRI‑defined scar patterns—especially in deeper layers—and why this technology may offer a valuable alternative when MRI is limited or unavailable. A concise look at emerging tools reshaping arrhythmic risk assessment.
Call to OrderRoll CallApproval of Minutes: December 14, 2025 Approval of AgendaReports of Officials and Committees: Mayor's Report Assembly Committee Reports Treasurer's Report Manager's Report Communications to the Assembly: Correspondence Hear Citizens PresentOrdinances, Resolutions, & Proclamations:Public Hearing, Second Reading, and Adoption Ordinance No. 26-02: Amending the FY26 Budget to Provide Funding for Public Works Shop Improvements and Public Works Consolidation Engineering, and Clinic Ultrasound Public Hearing, Second Reading, and Adoption Ordinance No. 26-03: Amending SMC 4.04 Management of Funds to Update Spending Authority Limits and Other Fund Management Regulations Unfinished Business: Review of Assembly Direction Regarding Summaries of Citizens' Comments in Assembly Minutes New Business: Direction for Garden City RV Park for 2027 Approval of Murphy Utility Easement Agreement Approval of Fee Proposal for Dredge Material Sampling, Characterization, & Reporting Incinerator Replacement Project Award of Project Contract Approval of Construction Administration Services Fee Proposal Clinic X-Ray Renovations ProjectAward of Project Contract Approval of Construction Administration Services Fee ProposalSchool Rehabilitation Phase 1 Project Award of Project Contract Approval of Construction Administration Services Fee Proposal Rockslide Maintenance Services Project Award of Project ContractApproval of Construction Administration Services Fee Proposal Mayor and Assembly Discussion ItemsExecutive SessionAdjournmentPacket
The Third Man by Graham Greene---Exploring Graham Greene's postwar classic, The Third Man, Jesan Sorrells and Ryan J. Stout unravel the psychology of unreliable narrators, leadership in times of nihilism, and the timeless challenge of ethical decision-making amid a world of grifters and cons. They dive into Greene's cinematic writing style, his nuanced character portrayals, and how postwar Vienna mirrors our own era of skepticism and manipulation. The conversation draws out practical leadership lessons—particularly the need for sincerity and humility—in a landscape shaped by both history and human nature.Book Title: The Third ManAuthor: Graham GreeneGuests: Jesan Sorrells (host), Ryan J. Stout (guest).---Time-Stamped Overview---00:00 "The Myth of Modern Nihilism."07:55 Graham Greene's Mastery of Characterization.12:38 "Relatable Characters and the Appeal of Dark Humor."20:30 "Graham Greene's Cinematic Legacy."24:03 "Post-War Struggles and Black Markets."31:58 Post-War Deals, Distrust, and Vienna.34:01 "Vienna's Loss and Legacy in The Third Man."39:21 "Friendship, Loneliness, and Keen Observation."48:00 "Observations, Language, and Hidden Motives."54:59 "AI Scams: Bots and Deception."59:01 "Children, Leadership, Ethics, and Modern Challenges."01:04:17 "Making Others Feel Heard & Valued."01:06:28 "Critiquing the 'Citizen of the World' Ideal."01:12:01 "Finding Meaningful and Spiritual Connections."01:18:18 "Harry Lime's Iconic Ferris Wheel Scene."01:26:27 "Recognizing Transformation Through Self-Love."01:29:33 "The Importance of Open-Minded Humility."01:37:47 "Moral Choices, Lost Knowledge, and Invention."01:42:29 Defending Free Speech and Objective Truth.01:45:51 "Film Versions and Orson Welles Radio."---Opening theme composed by Brian Sanyshyn of Brian Sanyshyn Music.---Pick up your copy of 12 Rules for Leaders: The Foundation of Intentional Leadership NOW on AMAZON!Check out the Leadership Lessons From the Great Books podcast reading list!--- ★ Support this podcast on Patreon ★
Is Time Really Linear? with Julia Mossbridge Julia Mossbridge, PhD, is a cognitive neuroscientist focused on understanding and training exceptional human performance including psi effects such as precognition, technological intuition, human-AI teaming, time, and accessing unconditional love. She is the co-founder and Board Chair of TILT: The Institute for Love and Time, Senior Distinguished Fellow in Human Potential at the Center for the Future of AI, Mind, and Society at Florida Atlantic University, Affiliate Professor in the Department of Biophysics and Physics at University of San Diego, Senior Data+Intuition Consultant at Tangible IQ, a member of the Alfred Lee Loomis Innovation Council at the Stimson Center, and the founder of Mossbridge Institute. Julia is author and coauthor of numerous books and scientific articles, including Transcendent Mind: Rethinking the Science of Consciousness with Imants Baruss; The Calling: A 12-Week Science-Based Program to Discover, Energize, and Engage Your Soul’s Work; The Premonition Code: The Science of Precognition, How Sensing the Future Can Change Your Life Paperback; and Have a Nice Disclosure. Her website is juliamossbridge.com Julia describes her research that explores the relationship between photons and time, “Replication and Characterization of the Causally Ambiguous Duration-Sorting (CADS) Effect”, that builds on the double-slit experiment. Through her exploration of bosonic particles, consciousness, and the past, present, and future, she suggests that the nature of time may be more like a braid than linear. By equating the informational substrate of the universe, that connects everything, with unconditional love, she demonstrates a connection of science and spirituality. 00:00:00 Introduction 00:03:42 Causally ambiguous research 00:05:08 The double-slit experiment and interference pattern 00:13:08 Collapsing the wave function 00:15:50 Presentiment or retrocausality 00:20:31 Time and space 00:29:36 Consciousness and universal love 00:34:50 The physics of love 00:50:05 Photons and mind-like particles 00:54:04 The past and future are in the present. 00:57:45 Conclusion New Thinking Allowed CoHost, Emmy Vadnais, OTR/L, is a licensed occupational therapist, intuitive healer and coach, and spiritual guide based in St. Paul, Minnesota. Emmy is the founder of the Intuitive Connections and Holistic OT communities. She is the author of Intuitive Development: How to Trust Your Inner Knowing for Guidance With Relationships, Health, and Spirituality. Her website is https://emmyvadnais.com (Recorded on January 23, 2026) For a short video on How to Get the Most From New Thinking Allowed, go to • InPresence 0253: How to Get the Most From … Check out our new website for the New Thinking Allowed Foundation at http://www.newthinkingallowed.org. There you will find our incredible, searchable database as well as our new, FREE QUARTERLY MAGAZINE. Also, opportunities to shop and to support our video productions. There, you can also subscribe to our FREE, WEEKLY NEWSLETTER! For a complete, updated list with links to all of our videos, see https://newthinkingallowed.com/Listin…. Check out New Thinking Allowed’s AI chatbot. You can create a free account at https://ai.servicespace.org When you enter the space, you will see that our chatbot is one of several you can interact with. While it is still a work in progress, it has been trained on 1,600 NTA transcripts. It can provide intelligent answers about the contents of our interviews. It’s almost like having a conversation with Jeffrey Mishlove. To buy a high-quality, printed version of the New Thinking Allowed Magazine, go to nta-magazine.magcloud.com. To join the NTA Psi Experience Community on Facebook, see / 1953031791426543 . To download and listen to audio versions of the New Thinking Allowed videos, visit our podcast at https://itunes.apple.com/us/podcast/n…. Download and read Jeffrey Mishlove’s Grand Prize essay in the Bigelow Institute competition, Beyond the Brain: The Survival of Human Consciousness After Permanent Bodily Death. https://www.bigelowinstitute.org/docs… If you would like to join our team of volunteers, helping to promote the New Thinking Allowed YouTube channel on social media, editing and translating videos, creating short video trailers based on our interviews, helping to upgrade our website, or contributing in other ways (we may not even have thought of), please send an email to friends@newthinkingallowed.com. To order Intuitive Development by Emmy Vadnais, click here: https://amzn.to/35sbLIA. To order New Thinking Allowed Dialogues: Is There Life After Death? click on https://amzn.to/3LzLA7Y To order Russell Targ: Ninety Years of ESP, Remote Viewing, and Timeless Awareness, go to https://amzn.to/4aw2iyr To order UFOs and UAP – Are We Really Alone?, go to https://amzn.to/3Y0VOVh To order a copy of Charles T. Tart: Seventy Years of Exploring Consciousness and Parapsychology, go to https://amzn.to/4oOUJLn
In this unusual pilot episode, two unlikely hosts are thrust together - Tom Duncan (GMOAT podcast) and Sara Shea (Shea Cinema) - in a journey of self-discovery and to discuss the prestige TV show, The West Wing, and its first season. The episode specifically covers the first three episodes of Season 1 from the fall of 1999.In this episode, they explain the concept of the show, what led them to deciding to make this new show, and what we can look forward to as they continue through Season 1 of The West Wing (1999-00).Chapters:00:00 Introduction to the Concept06:05 Curating Recommendations for TV Shows08:58 Exploring Different Formats for Discussion12:04 Choosing Our First Show: The West Wing15:01 Personal Connections to The West Wing17:55 Contextualizing The West Wing in Today's World20:59 Nostalgia and Reflection on 199923:54 Cultural Impact of The West Wing27:02 Closing Thoughts and Future Discussions27:03 Guessing the Top Artists of 199927:59 The Dominance of Santana and Rob Thomas29:44 The Rise of Latin Pop in the Late 90s30:40 The Impact of Pop Icons: Britney and Christina32:17 The Cultural Significance of 'The West Wing' Pilot34:39 Contextualizing the Show's Political Landscape36:31 The Evolution of POTUS in Popular Culture39:00 The Role of Technology in 199941:08 The Significance of Pagers vs. Cell Phones46:44 Immigration Issues Reflected in Media48:55 The Unexpected Cameo of Martin Sheen51:54 Character Dynamics and Development55:00 The Role of Music and Dialogue58:02 Casting and Character Relationships01:00:55 Political Themes and Historical Context01:04:03 Moral Dilemmas and Personal Stakes01:07:03 Emotional Resonance and Character Vulnerability01:10:02 Behind the Scenes of Politics01:12:54 Tribalism in Modern Politics01:16:06 Conclusion and Reflections on Political Discourse01:22:25 The Political Spectrum and Party Dynamics01:23:55 Emotional Resonance in Storytelling01:25:26 Character Development and Narrative Arcs01:26:32 The Impact of Personal Relationships on Leadership01:28:17 The Consequences of Military Decisions01:30:30 The Weight of Presidential Power01:32:22 The Role of Advisors in Governance01:34:57 Emotional Responses and Decision Making01:37:32 Symbolism and Characterization in Leadership01:40:53 Character Introductions and Future Developments01:41:16 Predictions for Future EpisodesKeywords:The West Wing, TV discussion, political drama, season one, character analysis, 90s television 1999, West Wing, politics, music, society, culture, 90s nostalgia, media, history
Intro 0:00 Podcast 01:12 Beck's Hybrids uses Product Characterization Research (PCR) to decide where each hybrid or variety will perform best before recommending it to farmers. 1️⃣ What “Product Characterization” Means It's a structured, multi-location testing system that answers: What soil types does this hybrid like? How does it respond to high vs. low fertility? Does it handle drought or wet conditions better? What population (seeding rate) maximizes yield? Is it defensive (stable) or offensive (high top-end yield)? How does it react to stress (heat, disease, compaction)? Instead of just asking “Does it yield well?”, PCR asks: Under what conditions does it yield best — and where should we place it? 2️⃣ How They Do It Beck's runs replicated field trials across many environments in the Midwest and beyond. They test hybrids under: Multiple planting populations Different fertility levels Various soil types Irrigated vs. dryland Tillage systems Stress scenarios (e.g., drought or disease pressure) This builds a performance profile for each hybrid or soybean variety. 3️⃣ Hybrid / Variety Placement Strategy After characterization, each product gets categorized by placement:
New research reveals that just twenty minutes of electric field exposure can trigger cellular damage that persists for over twenty generations in living organisms. In this episode, I examine a fascinating study that exposed aphids to high-voltage electric fields and tracked the biological effects across twenty-one generations. The findings reveal how brief electromagnetic exposures can create lasting changes in cellular antioxidant systems, offering important insights into the multi-generational effects of electric field exposure. In This Episode How twenty minutes of exposure affected twenty-one generations of organisms The role of oxidative stress in electromagnetic field damage Why antioxidant enzyme changes matter for long-term health Featured Study High-voltage electrostatic field-induced oxidative stress: Characterization of the physiological effects in Sitobion avenae (Hemiptera: Aphididae) across multiple generations. Read the full study at shieldyourbody.com/research
In this episode, Dr. Elizabeth Volkmann discusses emerging research on the gut microbiome in systemic sclerosis, building on findings from early-diagnosis and prior microbiome studies. She explains her team's analysis of microbiome-derived metabolites, including short-chain fatty acids, and their potential role in symptom development, highlighting key findings, clinical implications, and study limitations. The conversation also touches on holistic patient care, international collaboration, and her perspective on the future of systemic sclerosis research and treatment. Characterization of the Fecal Metabolome in Patients With Early Systemic Sclerosis
In this episode, Therese Markow and Dr. Kari Nadeau discuss the presence and health effects of microplastics in our bodies. Microplastics can enter our bodies through various environmental routes, including food, water, and air. They are in everyone's bodies to some degree. Microplastics have been linked to health issues like stroke, cancer, and heart attacks. Simple actions like avoiding single-use plastics and processed foods can reduce microplastic levels in the blood by up to 80% in three months. Dr. Nadeau emphasizes the need for further research and consumer awareness to mitigate plastic pollution. Key Takeaways: A microplastic, scientifically, is anything between 1 micron (the size of a red blood cell or an immune cell) to 5 millimeters (the size of a sesame seed). Anything smaller than that is a nanoplastic. Plastics are chemicals. Plastics, as we know them, did not exist before the 1940s. Now we see them in so many places, from healthcare to food to our clothing. In the US, we are getting about a credit card's worth of plastic per week in what we eat. In Indonesia, it is more like a credit card amount per day. The amount varies around the world. "We really need to think about air and water and soil as ways that these plastics can get into our bodies." — Dr. Kari Nadeau Episode References: Environmental Working Group: https://www.ewg.org/ Jung YS, et al. Characterization and regulation of microplastic pollution for protecting planetary and human health. Environ Pollut. 2022 Dec 15;315:120442. Ward CP, Reddy CM. We need better data about the environmental persistence of plastic goods, Proc. Natl. Acad. Sci. U.S.A. 117 (26) 14618-14621. Ziani K, Ioniță-Mîndrican CB, Mititelu M, Neacșu SM, Negrei C, Moroșan E, Drăgănescu D, Preda OT. Microplastics: A Real Global Threat for Environment and Food Safety: A State of the Art Review. Nutrients. 2023 Jan 25;15(3):617. Leslie, H. A. et al. (2022). Plastic particles in cosmetics and personal care products: A review. Science of the Total Environment, 822, 153406. https://www.fda.gov/food/environmental-contaminants-food/microplastics-and-nanoplastics-foods Connect with Dr. Kari Nadeau: Professional Bio & Studies: https://hsph.harvard.edu/profile/kari-c-nadeau/ Connect with Therese: Website: www.criticallyspeaking.net Bluesky: @CriticallySpeaking.bsky.social Instagram: @criticallyspeakingpodcast Email: theresemarkow@criticallyspeaking.net Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it.
Osteosarcoma Webinar Series: David Ulmert, MD, PhD, an Associate Professor at UCLA, discusses his OutSmarting Osteosarcoma funded work (Because of Sydney) on high-throughput characterization of pathobiological responses in osteosarcoma tumors treated with LRRC15-targeted radiotherapy to uncover curative co-treatment approaches.Dr. Ulmert will discuss his lab's work investigating how osteosarcoma responds to LRRC15-targeted radiotherapy, with patient translation anticipated this year. Using high-throughput technologies, the team will identify biomarkers, predictive models, and key transcriptional regulators driving the TGFβ–LRRC15 axis. He will review how radiopathobiological changes and immune reprogramming are being mapped to uncover druggable events and inform co-treatment strategies, accelerating near-term impact on patient studies and next-generation therapeutic development.Dr. David Ulmert is an expert in oncology and biotechnology, specializing in cancer biomarkers and targeted therapies. His research focuses on antigens secreted by luminal tissues as novel cancer-specific targets and circulating biomarkers. He developed high-affinity antibodies against androgen receptor-regulated enzymes hK2 and PSA, now in clinical trials across the US, Europe, and Australia—in collaboration with Janssen—for radioimmunotheranostics, CAR-T therapy, and bispecific targeting. His lab also developed DUNP19, an LRRC15-targeting antibody licensed to Lantheus, with a Phase 1 trial in osteosarcoma planned for 2025. Dr. Ulmert leads UCLA's Preclinical Theranostics Program and conducts population-based studies on cancer biomarkers and risk factors with international collaborators. He is widely recognized for advancing prostate cancer research and translational immunotheranostics.
Dr. Sudeep Soni explores the evolving role of dual–contrast agent liver MRI for improved characterization of focal liver lesions when single-agent protocols are limited. The episode breaks down how sequential use of extracellular and hepatobiliary contrast agents enhances diagnostic confidence, reduces uncertainty, and supports more informed patient care decisions. Dual–Contrast Agent Liver MRI for Liver Lesion Characterization. Shetty et al. RadioGraphics 2026; 46(1):e250113.
In this episode, Jeff and Claire talk about Claire's new book "Write Iconic Characters" in which Claire uses the Enneagram to show how to write diverse characters. Claire has also been on the show in Episode 100 and Episode 229. You can find Claire's book here: https://www.amazon.com/Write-Iconic-Characters-motivations-unforgettable-ebook/dp/B0FRV351Y8/ Also check out Claire's coaching at https://www.liberatedwriter.com/claire And for more on the craft of writing, check out DialogueDoctor.com
In this spoiler-filled review, we break down Dead Ringer by Chris Hauty, a political thriller centered on JFK assassination conspiracy theories, Cold War espionage, and modern intelligence operations.We analyze the full plot, major twists, and dual-protagonist structure, dig into how the novel reimagines the JFK conspiracy, and discuss what works, what strains credibility, and how Dead Ringer compares to other conspiracy-driven thrillers.If you enjoy political thrillers, CIA intrigue, historical conspiracies, and deep spoiler discussions, this episode goes all in.—
FERGUSON'S ANALYSIS, THE EMPEROR SYSTEM, AND AUGUSTAN AUTHORITY Colleagues Gaius and Germanicus, Friends of History Debating Society, Londinium, 91 AD. The speakers critique historian Niall Ferguson's recent characterization of Donald Trump as a composite of Andrew Jackson, William McKinley, P.T. Barnum, and Richard Nixon. Germanicus dismisses Ferguson's analysis as a cynical attempt to force a conventional republican narrative onto what is actually a systemic shift toward an "emperor system." He argues that the Americanpublic has embraced this imperial transition due to the "ruin" and dysfunction of the traditional republic caused by a corrupt elite. While Ferguson attempts to minimize Trump's significance by linking him to past politicians like the "salesman" Barnum or the "aristocratic" Jackson, Germanicus asserts that the "gold leaf" aesthetic of the Trump era correctly signals a return to Augustan authority. The conversation concludes by contrasting the necessary "dignitas" of future American emperors with the degradation of the office under Bill Clinton, whom Germanicus describes as ethically "worse than Tiberius" due to his association with the Epstein scandal. They finish by reflecting on the resilience of the Byzantine emperors, such as Basil II, who successfully maintained imperial continuity for centuries through strong leadership. NUMBER 3
Deze week hoor je in NRC Vandaag onze serie Wilde eeuwen, het begin. Een van de verhalende series die we dit jaar maakten: perfect voor tijdens de dagen rond Kerst.Het is 3.200 jaar geleden. Schrijver Sîn-leqi-unnini verwerkt zijn angsten in een episch verhaal over Gilgamesj. Zal dat indruk maken op de nieuwe Babylonische koning? Heeft u vragen, suggesties of ideeën over onze journalistiek? Mail dan naar onze ombudsman via ombudsman@nrc.nl.Voor deze aflevering is onder meer gebruikt gemaakt van deze literatuur:Karen Sonik. ‘Characterization and Identity in Mesopotamian Literature: The Gilgamesh Epic, Enuma elish, and Other Sumerian and Akkadian Narratives' in Dahlia Shehata e.a. (eds) Contemporary Approaches to Mesopotamian Literature. How to Tell a Story, Brill 2024. Sophus Helle. ‘Gilgamesh Returns' in Articulations, in juni 2024.Amanda H. Podany. 'Weavers, Scribes, and Kings A New History of the Ancient Near East', Oxford University Press 2022. Sophus Helle. 'Gilgamesh: A New Translation of the Ancient Epic', Yale University Press 2021 Andrew George. 'The Epic of Gilgamesh. The Babylonian Epic Poem and Other Texts in Akkadian and Sumerian', Penguin 2020 (tweede druk).Herman van Stiphout. 'Het epos van Gilgames', SUN 2011 (derde druk). Gwendolyn Leick (ed). 'The Babylonian world', Routledge 2007 Benjamin R. Foster. 'Before the muses: an anthology of Akkadian literature', CDL Press 2005 (derde druk). Zie ook ‘Het epos van Gilgamesj: hoe een held mens wordt' in NRC op 6 juli 2019.Tekst en presentatie: Hendrik SpieringRedactie en regie: Mirjam van ZuidamMuziek, montage en mixage: Rufus van BaardwijkBeeld: Jeen BertingVormgeving: Yannick MortierZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.
Welcome to Anime Watch Club, a bi-weekly group discussion and review where the hosts of the what do you say anime podcast, nominate and vote on shows either that we haven't seen or shows that will hopefully lead to a great discussion. On todays episode, we will be reviewing the 2025 anime Ave Mujica.Socials/Discord - linktr.ee/whatdoyousayanime0:00 - Intro1:28 - First impressions11:15 - Subway Takes about the portrayal of mental illness30:34 - The Characterization of the cast38:43 - Picking up things on a rewatch43:28 - Favorite episodes49:50 - The lack of a band and music in a Girls Band show (and a 2nd hot take from Miles)55:06 - What we want to see in season 21:02:44 - AVE is EVA1:06:52 - Closing thoughts and scores1:19:48 - What we're watching next
Episode 150 - Fate Be Changed by Farrah RochonDid We Read the Same Book?This week, Sam and Kaitlyn are genuinely confused — and not in a fun mystery way. Fate Be Changed left us with questions we still can't answer, starting with why this author was chosen to write this book (no, really… why?), and spiraling into issues with characterization, time travel logic, and cliffhangers that feel less “exciting” and more “cheap.”We unpack what happens when a story feels pantsed instead of planned, from dropped subplots and disjointed storytelling to a complete inability to decide what the overarching plot is supposed to be. If you've ever finished a book and thought “Did I miss something… or did the book?” — this episode is for you.New episodes every Monday at 8 AM EST ✨Next week: Prince Caspian by C.S. Lewis⏱️ Time Stamps00:56 Background06:58 Age Level & Content Warning09:06 Judge a Book by It's Cover10:28 Discussion - Why This Author?16:09 Characterization & Cheap Cliffhangers20:33 Time Travel Mechanics and Cliches26:50 Outline or Pantsing? Either Way Pick a Plot57:21 General Thoughts01:00:24 One Question for the Author01:05:47 Rating01:09:10 Read Again?01:09:46 Favorite of the Series so Far01:10:26 Outro
This week on Men of Steel, Case and Jmike are joined by Kris Ingersoll (Media/Lit, Batman By The Numbers) to talk about the 1990 World's Finest miniseries! We dig into how this story redefined the dynamic between Superman and Batman, the tone of early '90s DC, and why this team-up still holds up decades later. #MenOfSteelPod #WorldsFinest #Superman #Batman #DCComics #ComicsPodcast #KrisIngersoll Support us on Patreon! https://www.patreon.com/CertainPOVMedia Men of Steel Full Episode Originally aired: December 5, 2025 Edited by Sophia Ricciardi Scored by Geoff Moonen Certain Point Of View is a podcast network brining you all sorts of nerdy goodness! From Star Wars role playing, to Disney day dreaming, to video game love, we've got the show for you! Learn more on our website: https://www.certainpov.com Join us on Discord: https://discord.gg/wcHHer4 PODCAST SHOWS: ▶ Men Of Steel - https://www.certainpov.com/men-of-steel FOLLOW US: ▶ Twitter: @certainpovmedia @menofsteelpod ▶ Instagram: @certainpovmedia Outline ️ Introduction to Podcast and Guests (00:00 - 02:51) Hosts Case Aiken and Jmike Folson introduce the episode and guest Kris Ingersoll, who runs a Batman podcast and co-hosts Media Lit podcast. Topic: The 1990 DC Comics miniseries World's Finest by Dave Gibbons and Steve Rood. Contextual Background of the 1990 World's Finest (02:51 - 05:34) The miniseries releases shortly after Crisis on Infinite Earths and John Byrne's Man of Steel reboot (1986). Post-Dark Knight Returns, Batman and Superman's relationship had changed, characterized by distance rather than camaraderie. ️ Plot Overview (05:34 - 08:14) Lex Luthor and Joker team up to take over Gotham and Metropolis with intertwined but largely separate schemes. Batman and Superman investigate, culminating in events involving an orphanage, a nuclear reactor, and city-wide explosions. Decompression and Story Structure Critique (08:14 - 11:34) Discussion of story pacing issues: The narrative is elongated with side elements (e.g., orphan kids) that do not cohesively tie in. Emphasis on character moments over tight plotting. Initial Impressions and Artistic Elements (11:34 - 17:59) Chris praises the visual storytelling and art, referencing the use of parallel imagery and distinctive flashback watercolor style. Noted the deliberate design choices to echo Silver Age and Max Fleischer era Superman and early Batman. ️ Characterization of Villains and Supporting Cast (17:59 - 30:39) Joker portrayed in a "zany," less menacing mode, more a prankster than murderously malicious. Lex Luthor features a robotic hand and operates like a mob boss, balancing businessman and villain traits. Character Dynamics and Relationships (30:39 - 40:21) Lois Lane and Bruce Wayne's interactions highlight mutual suspicion and gradual respect. Batman and Superman's knowledge of each other's secret identities is subtle initially, revealed more overtly in third issue. ️ Themes and Continuity Notes (40:21 - 50:27) Orphanage is a thematic midpoint between Gotham and Metropolis, symbolizing shared orphan backgrounds of Batman, Superman, and villain. The book emphasizes orphans and legacy but does not fully develop these thematic elements. Technical and Artistic Praise (50:27 - 52:58) Art and character design praised for classic yet fresh look; great use of tableau pages showing Gotham and Metropolis. Noted the Batmobile's stylish design and Batman's athletic, sleek physique. Character in Action: Batman and Superman (52:58 - 59:55) Batman characterized as efficient, brutal, and action-focused. His use of Batarangs and disguises recognized as authentic. Superman rendered as powerful but more grounded Burn era 'cop,' balancing investigative journalism and heroic strength. Artistic and Thematic Highlights (59:55 - 01:09:46) Memorable moments include Superman carrying a nuclear reactor into space to save Metropolis. Subtle details such as Clark Kent's mannerisms and investigative approach noted. Overall Assessment and Legacy (01:09:46 - 01:14:36) The miniseries serves as a valuable snapshot of Batman and Superman dynamics post-Crisis and pre-mid-90s crossovers. While the narrative is considered "vibes-over-story," the series offers essential character moments, iconic imagery, and era-specific continuity. Conclusion and Promotions (01:14:36 - 01:19:44) Guests share social media handles and podcast info. Hosts plug "Trade School" podcast and Certain POV Discord for further comic discussions.
Program notes:0:40 CVD risk factors and texting1:40 How many undergo screening?2:41 Impact of personalized messaging3:25 Decentralized trials versus centralized 4:25 Decentralized much larger5:25 Does the trial move in one way or another?6:15 Two studies related to use of peripregnancy GLP-1 use7:15 Stopping at pregnancy8:15 Is overweight worse than stopping?9:00 Machine learning model, tissues, genetics and age10:00 Practical for assessing genetic basis11:00 Sequential tissue samples11:57 End
Did you know that a single crumb of bread is enough to cause an autoimmune response in children with celiac disease? Dr. Pankaj Vohra, Professor of Pediatrics and Board-Certified Pediatric Gastroenterologist, joins medical student Andrea Smith to discuss the evaluation and management of celiac disease, as well as essential guidance for following a gluten-free diet. Specifically, they will: Review the epidemiology of celiac disease and identify common symptoms and presentations of celiac disease Describe the pathophysiology of celiac disease including histopathological changes to the duodenum Identify diagnostic tests and criteria for diagnosing celiac disease in the pediatric population Identify common sources of gluten and the basics of identifying gluten on food labels Discuss typical management of celiac disease including appropriate screening tests and managing accidental gluten ingestion Special thanks to Dr. Rebecca Yang and Dr. Neeharika Bade for peer reviewing this episode. CME available free with sign up: Link coming soon! References: Bolia, R., & Thapar, N. (2023). Celiac Disease in Children: A 2023 Update. In Indian Journal of Pediatrics. Springer. https://doi.org/10.1007/s12098-023-04659-w Gidrewicz, D., Potter, K., Trevenen, C. L., Lyon, M., & Butzner, J. D. (2015). Evaluation of the ESPGHAN celiac guidelines in a North American pediatric population. American Journal of Gastroenterology, 110(5), 760–767. https://doi.org/10.1038/ajg.2015.87 Hill, I. D., Fasano, A., Guandalini, S., Hoffenberg, E., Levy, J., Reilly, N., & Verma, R. (2016). NASPGHAN clinical report on the diagnosis and treatment of gluten-related disorders. Journal of Pediatric Gastroenterology and Nutrition, 63(1), 156–165. https://doi.org/10.1097/MPG.0000000000001216 Husby, S., Koletzko, S., Korponay-Szabó, I., Kurppa, K., Mearin, M. L., Ribes-Koninckx, C., Shamir, R., Troncone, R., Auricchio, R., Castillejo, G., Christensen, R., Dolinsek, J., Gillett, P., Hróbjartsson, A., Koltai, T., Maki, M., Nielsen, S. M., Popp, A., Størdal, K., … Wessels, M. (2020). European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020. In Journal of Pediatric Gastroenterology and Nutrition (Vol. 70, Issue 1, pp. 141–156). Lippincott Williams and Wilkins. https://doi.org/10.1097/MPG.0000000000002497 Nenna, R., Tiberti, C., Petrarca, L., Lucantoni, F., Mennini, M., Luparia, R. P. L., Panimolle, F., Mastrogiorgio, G., Pietropaoli, N., Magliocca, F. M., & Bonamico, M. (2013). The celiac iceberg: Characterization of the disease in primary schoolchildren. Journal of Pediatric Gastroenterology and Nutrition, 56(4), 416–421. https://doi.org/10.1097/MPG.0b013e31827b7f64 Sahin, Y. (2021). Celiac disease in children: A review of the literature. In World Journal of Clinical Pediatrics (Vol. 10, Issue 4, pp. 53–71). Baishideng Publishing Group Co. https://doi.org/10.5409/wjcp.v10.i4.53 Salden, B. N., Monserrat, V., Troost, F. J., Bruins, M. J., Edens, L., Bartholomé, R., Haenen, G. R., Winkens, B., Koning, F., & Masclee, A. A. (2015). Randomised clinical study: Aspergillus niger-derived enzyme digests gluten in the stomach of healthy volunteers. Alimentary Pharmacology and Therapeutics, 42(3), 273–285. https://doi.org/10.1111/apt.13266 Schuppan, D., Mäki, M., Lundin, K. E. A., Isola, J., Friesing-Sosnik, T., Taavela, J., Popp, A., Koskenpato, J., Langhorst, J., Hovde, Ø., Lähdeaho, M.-L., Fusco, S., Schumann, M., Török, H. P., Kupcinskas, J., Zopf, Y., Lohse, A. W., Scheinin, M., Kull, K., … Greinwald, R. (2021). A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease. New England Journal of Medicine, 385(1), 35–45. https://doi.org/10.1056/nejmoa2032441 Tack, G. J., van de Water, J. M. W., Bruins, M. J., Kooy-Winkelaar, E. M. C., van Bergen, J., Bonnet, P., Vreugdenhil, A. C. E., Korponay-Szabo, I., Edens, L., von Blomberg, B. M. E., Schreurs, M. W. J., Mulder, C. J., & Koning, F. (2013). Consumption of gluten with gluten-degrading enzyme by celiac patients: A pilot-study. World Journal of Gastroenterology, 19(35), 5837–5847. https://doi.org/10.3748/wjg.v19.i35.5837 Husby S, Koletzko S, Korponay-Szabó IR, et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012; 54: 136–160
Join Marcus Drake, Anthony Kanai, and Tufan Tarcan as they unpack the science behind urinary tract coordination, sharing insights from their round table at ICS-EUS 2025 Abu Dhabi. ICS Masterclass: Personalizing Care for Patients with OABTuesday, 25 November 2025 | 16:30 - 18:00 GMTwww.ics.org/masterclassJoin our highly interactive ICS Masterclass, chaired by Howard B Goldman, and engage directly with an outstanding panel of experts. This dynamic session invites you to share experiences, ask questions, and learn from leading specialists in urology and urogynaecology.Through its annual meeting and journal, the International Continence Society (ICS) has been advancing multidisciplinary continence research and education worldwide since 1971. Over 3,000 Urologists, Uro-gynaecologists, Physiotherapists, Nurses and Research Scientists make up ICS, a thriving society dedicated to incontinence and pelvic floor disorders. The Society is growing every day and welcomes you to join us. If you join today, you'll enjoy substantial discounts on ICS Annual Meeting registrations and free journal submissions. Joining ICS is like being welcomed into a big family. Get to know the members and become involved in a vibrant, supportive community of healthcare professionals, dedicated to making a real difference to the lives of people with incontinence.
In this episode, we feature some of the winners of poster and oral presentation competitions at the 2025 ADSA Annual Meeting in Louisville, Kentucky. Abstracts can be found here: ADSA 2025 Annual MeetingMS Oral Presentation, ProductionGuests: Trinidad Fernandez-Wallace and Dr. Lautaro Rostoll-Cangiano, University of Wisconsin-MadisonCo-host: Dr. Laura Niehues, BalchemAbstract 1218: Immunity at the crossroads of cellular metabolism: Navigating T helper shifts in the periparturient period of dairy cows. (0:08)Trinidad found that T-helper cell metabolism and proliferation were both upregulated after calving, which may impact the effectiveness of immune responses during the transition period. The group discusses if T-helper cells could be used as a marker of inflammation in the future and how Trinidad's results may have been different if samples had been collected between 3 and 28 days after calving.PhD Oral Presentation, ProductionGuests: Natnicha Taechachokevivat and Dr. Rafael Neves, Purdue UniversityCo-host: Dr. Sion Richards, Balchem Abstract 1107: Relationships between systemic inflammation, subclinical hypocalcemia, and hyperketonemia in clinically healthy Holstein cows. (8:07)Natnicha investigated the association of plasma haptoglobin (an inflammatory marker) on days 1 and 3 in milk with subclinical hypocalcemia and hyperketonemia. Systemic inflammation appears to be associated with subclinical hypocalcemia and hyperketonemia and reduced milk yield in multiparous cows. When multiparous cows exhibited both inflammation and metabolic disease indicators, they produced less milk; however, when primiparous cows exhibited both inflammation and metabolic disease indicators, they produced more milk. 3 Minute ThesisGuests: Savitha Saikumar and Dr. Diwaker Vyas, University of FloridaCo-host: Dr. Laura Niehues, BalchemAbstract 1548: Effects of peripartal supplementation of prototype postbiotics on intake, rumen fermentation, colostrum quality, and performance in transition dairy cows. (15:14)Savitha investigated the effects of a prototype postbiotic supplement in transition cows from 35 days before calving to 63 days after calving. Cows on the postbiotic treatment received 25 grams per day topdressed on their TMR. Before calving, the postbiotic had no effect on dry matter intake, body condition sore, body weight, or total VFAs. After calving, the postbiotic increased dry matter intake and milk yield after 6 weeks, and increased energy-corrected milk and fat-corrected milk with no effect on body weight, body condition score, or rumen fermentation profile.PhD Poster Guest: Amanda Fischer-Tlustos, University of Guelph Abstract 2012: Characterization of dry-period mammary acetate and glucose metabolism and their association with colostrum production in multiparous Holstein cattle. (25:15)Amanda's research evaluated acetate and glucose metabolism in the mammary gland during the dry and calving periods to better understand how colostrum is made. Acetate uptake by the udder remained fairly constant until one week before calving, when it started to increase. Glucose uptake did not increase until the onset of calving. Previous lactation milk production and far-off mammary metabolism were both negatively correlated with colostrum production. Amanda hypothesizes that high producing cows who have trouble drying off may have high amounts of metabolic activity in the mammary gland when they should have low activity, which may result in lower colostrum production at the subsequent calving. PhD Oral Presentation, Southern Branch DivisionGuests: Bridger Sparks and Dr. Clarissa Strieder-Barboza, Texas Tech UniversityCo-host: Dr. Ryan Pralle, BalchemAbstract 1215: Adipose tissue neuro-like cell profile changes with ketosis in dairy cows. (33:05)Bridger investigated neuro-like cells in the adipose tissue of cows with or without subclinical ketosis. The transcriptional profile of neuro-like cells changed when collected from cows with subclinical ketosis, which may indicate a potential regulatory role in adipose tissue metabolism. Perhaps modulation of neuro-like cells could potentially alleviate excessive adipose mobilization in the postpartum period. ADSA Graduate Student Division HighlightsGuests: Evelyn Yufeng Lin, North Carolina State University; Miranda Farricker, Cornell University; Conor McCabe, University of California-Davis; Dr. Maurice Eastridge, Ohio State University. (40:45) Dr. Eastridge is the chair of the ADSA Foundation and explains some of the Foundation's current projects. Evelyn and Conor are past presidents of the ADSA Graduate Student Division, and Miranda is the incoming president. Each student gives a bit of background on themselves and their research and describes what the Graduate Student Division does and how they foster new graduate students in ADSA. Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table. If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.
Fr. Mike draws our attention to the descriptions of wisdom found in our readings for today and reflects on the beauty of wisdom's feminine nature. He also discusses the death of Antiochus Epiphanes and offers two perspectives on reconciling God's role in suffering. Today's readings are from 2 Maccabees 9, Wisdom 7-8, and Proverbs 25:1-3. For the complete reading plan, visit ascensionpress.com/bibleinayear. Please note: The Bible contains adult themes that may not be suitable for children - parental discretion is advised.
Drs. Maria Mojica, Robert Bonomo, and Ryan Shields join Dr. Erin McCreary (@erinmccreary) for a Halloween special reviewing the scariest resistance mechanisms and baddest bugs – Burkholderia spp., Achromobacter spp., and Elizabethkingia spp. Never have beta lactamase enzymes and other complexities been explained so hauntingly well. We don't want to spook you, but these environmental, opportunistic pathogens are found around the globe. While we hope you don't encounter them, take a listen to prepare in case one jumps out in your practice! This episode was sponsored by an unrestricted grant from Shionogi Inc. References: Spencer HK, Spitznogle SL, Borjan J, Aitken SL. An Overview of the Treatment of Less Common Non-Lactose-Fermenting Gram-Negative Bacteria. Pharmacotherapy. 2020 Sep;40(9):936-951. doi: 10.1002/phar.2447. Epub 2020 Aug 14. PMID: 32687670. Defining antimicrobial susceptibility testing methods and breakpoints among Achromobacter species SIDP 2025 Webinar | Mind the Gap: CLSI M100 Updates to Optimize Stewardship and Patient Care Outcomes Yasmin M, Rojas LJ, Marshall SH, Hujer AM, Cmolik A, Marshall E, Boucher HW, Vila AJ, Soldevila M, Diene SM, Rolain JM, Bonomo RA. Characterization of a Novel Pathogen in Immunocompromised Patients: Elizabethkingia anophelis-Exploring the Scope of Resistance to Contemporary Antimicrobial Agents and β-lactamase Inhibitors. Open Forum Infect Dis. 2023 Jan 31;10(2):ofad014. doi: 10.1093/ofid/ofad014. PMID: 36820316; PMCID: PMC9938519. Warner NC, Bartelt LA, Lachiewicz AM, Tompkins KM, Miller MB, Alby K, Jones MB, Carr AL, Alexander J, Gainey AB, Daniels R, Burch AK, Brown DE, Brownstein MJ, Cheema F, Linder KE, Shields RK, Longworth S, van Duin D. Cefiderocol for the Treatment of Adult and Pediatric Patients With Cystic Fibrosis and Achromobacter xylosoxidans Infections. Clin Infect Dis. 2021 Oct 5;73(7):e1754-e1757. doi: 10.1093/cid/ciaa1847. PMID: 33313656; PMCID: PMC8678443. El Chakhtoura NG, Saade E, Wilson BM, Perez F, Papp-Wallace KM, Bonomo RA. A 17-Year Nationwide Study of Burkholderia cepacia Complex Bloodstream Infections Among Patients in the United States Veterans Health Administration. Clin Infect Dis. 2017 Oct 15;65(8):1253-1259. doi: 10.1093/cid/cix559. PMID: 29017247; PMCID: PMC5848224.
It's been a little over two weeks since President Donald Trump promoted a highly disputed link between Tylenol use during pregnancy and autism. And reaction remains strong. As St. Louis Public Radio's Jason Rosenbaum reports, the area's autistic community contends the GOP president is rolling back progress that helped people with the neurological disorder better integrate into society.
This week, please join authors Joseph Campain and Gregory Lewis, as well as Section Editor Satyam "Tom" Sarma as they discuss the article "Characterization and Application of Novel Exercise Recovery Patterns That Reflect Cardiac Performance: A Substudy of the SEQUOIA-HCM Randomized Trial." For the episode transcript, visit: https://staging.www.ahajournals.org/do/10.1161/podcast.20251006.208532
Think military divorce means automatically splitting everythign 50/50 and going to court? Wrong on both counts! Certified Divorce Financial Anaylst David Smith reveals what most military families get wrong and what it costs them! In today's episode, we'll discuss the complex financial and logistical aspects of military divorce, covering everything from pension division to healthcare benefits, tax implications, and emotional support strategies. Key Topics Jurisdiction & Legal Considerations Multiple state options for filing (voting state, property ownership state, driver's license state, tax filing state) Importance of consulting with an attorney early to determine proper jurisdiction Each state has different rules, formulas, and processes JAG office can provide consultation but cannot represent service members in divorce proceedings Types of Divorce Processes Four main options: DIY without professionals, mediation, collaborative divorce, litigation Court is NOT the only option Out-of-court processes (mediation, collaborative) are often more cost-effective, private, and less stressful Consulting attorneys vs. representing attorneys - different roles and costs Military Pension Division Division is not the only option - can use offsetting with other assets Must determine what portion is "marital" vs. "separate" property Not all pension components are divisible (e.g., VA disability) Requires a Military Retirement Pay Division Order through DFAS Differences between active duty, reservist, and guard member pensions Survivor Benefit Plan (SBP) Critical considerations: Only ONE SBP beneficiary can be named Previous spouses from earlier marriages may already occupy the "SBP chair" Premium costs must be negotiated Former spouse can be SBP beneficiary even without receiving pension payments Time-sensitive: Required forms must be submitted within specific timeframe or rights are lost Cannot be automatically transferred - requires proper paperwork TRICARE Benefits Courts CANNOT order TRICARE coverage - falls under federal rules Key rules: 20-20-20 (full benefits for life), 20-20-15 (transitional benefits) Based on: length of marriage, service member's creditable years, overlap period COBRA-like option available if don't meet other rules GI Bill Transfer Must be transferred WHILE married - cannot go to former spouse after divorce Service member can rescind the transfer Can be transferred to children as alternative Settlement agreement language is critical to protect this benefit Thrift Savings Plan (TSP) Multiple TSPs possible (civilian federal employee spouse, reservist who went active duty) Pre-tax and Roth portions have different tax consequences Must account for outstanding loans Requires Retirement Benefits Court Order (different from pension division order) Not always split - can use offset method with other assets Other Unique Military Assets to Consider Military leave - has monetary value on LES Credit card points and miles - can be worth $30,000-$40,000 USAA Subscriber Savings Account Pets - especially valuable show animals Life insurance policies Tax Implications Filing status changes Tax bracket shifts Capital gains considerations when dividing assets Pre-tax accounts (traditional IRA, 401k) vs. post-tax accounts have different real values Child tax credits and claiming dependents Early withdrawal penalties Marital vs. Separate Property Separate property: assets brought into marriage, inheritances, gifts (if kept separate and not commingled) Marital property: everything accumulated during marriage Characterization process is essential before division discussions Financial Mistakes to Avoid Making verbal agreements before completing full financial inventory Not understanding tax consequences of asset division Overlooking hidden assets (leave balance, points/miles, etc.) Rushing decisions - most divorce decisions have no do-overs Not considering pre-tax vs. post-tax asset values Misclassifying assets as marital or separate Practical First Steps Learn about all four divorce process options If abuse is present, seek legal counsel immediately Open credit card and bank account in your own name Create timeline of important dates and duty stations Gather supporting documents (tax returns, bank statements) in cloud storage Document account numbers, login credentials, passwords Consider consulting with CDFA before hiring representing attorney Supporting Someone Through Divorce Listen deeply and empathetically Avoid projecting your own divorce experience onto theirs Don't rush them into decisions Offer practical help (childcare, meals, house cleaning) Point them to resources (counselors, family services, professionals) Give them breathing room Key Takeaways Divorce in the military involves unique complexities beyond civilian divorces Court is not the only option - consider mediation or collaborative processes Complete financial inventory BEFORE making division decisions Everything accumulated during marriage is generally marital property Professional guidance (CDFA, attorney consultation) is an investment, not just a cost Most divorce decisions are final with no do-overs - take time to understand options Resources & Links David's website: sandoakdivorcesolutions.com Free 30-minute phone consultations available David's LinkedIn: linkedin.com/in/davidsmithcdfa/ Find a CDFA through Institute for Divorce Financial Analysts: institutedfa.com Spencer and Jamie offer one-on-one Military Money Mentor sessions. Get your personal military money and personal finance questions answered in a confidential coaching call. militarymoneymanual.com/mentor Over 20,000 military servicemembers and military spouses have graduated from the 100% free course available at militarymoneymanual.com/umc3 In the Ultimate Military Credit Cards Course, you can learn how to apply for the most premium credit cards and get special military protections, such as waived annual fees, on elite cards like The Platinum Card® from American Express and the Chase Sapphire Reserve® Card. https://militarymoneymanual.com/amex-platinum-military/ https://militarymoneymanual.com/chase-sapphire-reserve-military/ Learn how active duty military, military spouses, and Guard and Reserves on 30+ day active orders can get your annual fees waived on premium credit cards in the Ultimate Military Credit Cards Course at militarymoneymanual.com/umc3 If you want to maximize your military paycheck, check out Spencer's 5 star rated book The Military Money Manual: A Practical Guide to Financial Freedom on Amazon or at shop.militarymoneymanual.com. Want to be confident with your TSP investing? Check out the Confident TSP Investing course at militarymoneymanual.com/tsp to learn all about the Thrift Savings Plan and strategies for growing your wealth while in the military. Use promo code "podcast24" for $50 off. Plus, for every course sold, we'll donate one course to an E-4 or below- for FREE! If you have a question you would like us to answer on the podcast, please reach out on instagram.com/militarymoneymanual.
Masters of the Air, the incredible series from Tom Hanks and Steven Spielberg, closes out our mini-series on World War II projects. Greg Cass from the Long Take Review, joins the show to chat about the air war in Europe and to try to understand the courage it took to get in those planes day after day.Topics Discussed Include:1. The Horrors of the Air War2. The Characterization of the Men in the Planes3. The Inclusion of the Tuskegee AirmenSupport the show on Patreon - www.patreon.com/forceghostconversationsIf you want to continue the conversation, please follow us at the following websites:Blue SkyThreadsTwitterFacebookInstagramYouTubeMerchandise
Contaminated Site Clean-Up Information (CLU-IN): Internet Seminar Audio Archives
In 2020, ITRC's 1,4-Dioxane team created multiple tools and documents that provide information to assist all interested stakeholders in understanding this contaminant and for making informed, educated decisions. Since the 1950s, 1,4-Dioxane has seen widespread use as a solvent stabilizer. The use of solvents through the 1980s suggests its presence at thousands of solvent sites in the US; however, it is not always a standard compound in typical analytical suites for hazardous waste sites, so it previously was overlooked. The U.S. EPA has classified 1,4-Dioxane as "likely to be carcinogenic to humans." Some states have devised health standards or regulatory guidelines for drinking water and groundwater standards; these are often sub-part per billion values. These low standards present challenges for analysis, characterization, and remediation of 1,4-Dioxane. The 1,4-Dioxane: Science, Characterization & Analysis, and Remediation training is a series of six (6) modules. The six individual modules will be presented together live, and then archived on the ITRC 1,4-Dioxane training webpage for on demand listening. The modular 1,4-Dioxane training series provides an overview of 1,4-Dioxane and presenting six sections from the ITRC guidance document (1,4d-1, 2021):History of Use and Potential Sources (Sect 1)Regulatory Framework (Sect 2)Fate and Transport (Sect 3)Sampling and Analysis (Sect 4)Toxicity and Risk Assessment (Sect 5)Remediation and Treatment Technologies (Sect 6)After the six-part 1,4-Dioxane: Science, Characterization & Analysis, and Remediation series, you should understand:The history of 1,4-Dioxane manufacturing and usage and the potential sources of releases of 1,4-Dioxane to the environment.Primary state and U.S. federal regulatory programs of relevance to 1,4-DioxaneKey physical/chemical properties, and fate and transport processes that are relevant for 1,4-DioxaneBenefits and limitations of the available analytical methodsRisk drivers for human health and how ecological risk comparesHow/when/why different treatment technologies are appropriate We encourage you to use the ITRC 1,4-Dioxane products (14d-1) and these training modules to learn about 1,4-Dioxane and how you can apply these best practices to improve decision-making at your sites. For regulators and other government agency staff, this understanding of 1,4-Dioxane can be incorporated into your own programs. This training summarizes the current understanding of 1,4-Dioxane. While the training makes every effort to keep the information accessible to a wide audience, it is assumed that the participants will have some basic technical understanding of chemistry, environmental sciences, and risk assessment. As with other emerging contaminants, our understanding of 1,4-Dioxane continues to advance. This training provides the participants with information on areas where the science is evolving and where uncertainty persists. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/itrc/14D-1_091625/
Welcome to Watch Club, a bi-weekly group discussion and review where the hosts of the what do you say anime podcast, nominate and vote on shows either that we haven't seen or shows that will hopefully lead to a great discussion. On todays episode we will reviewing the first season of Kamisama Kiss.Spoiler warning ahead for Fruits Basket as wellMinor audio issue in the intros Socials/Discord - https://linktr.ee/whatdoyousayanime0:00 Intro2:12 First Impressions10:07 Synopsis11:44 Beginnings and Building Plot20:50 Supporting Cast27:36 Handling the Romance37:02 Theming, Messaging and Characterization 50:30 Misc. Things We Liked56:47 Final Thoughts and Rating1:05:46 What We're Watching Next
Joseph Mikhael, MD, and Surbhi Sidana, MD, discuss the importance of balancing treatment intervals, managing side effects, and maximizing quality of life in multiple myeloma patients. Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002713. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Acyclovir Prophylaxis Against Varicella Zoster Virus Reactivation in Multiple Myeloma Patients Treated With Bortezomib-Based Therapies: A Retrospective Analysis of 100 Patients https://pubmed.ncbi.nlm.nih.gov/22222250/ Monitoring, Prophylaxis, and Treatment of Infections in Patients With MM Receiving Bispecific Antibody Therapy: Consensus Recommendations From an Expert Panel https://pubmed.ncbi.nlm.nih.gov/37528088/ Characterization of Dysgeusia and Xerostomia in Patients With Multiple Myeloma Treated With the T-Cell Redirecting GPRC5D Bispecific Antibody Talquetamab https://pubmed.ncbi.nlm.nih.gov/38092979/ Idecabtagene Vicleucel for Relapsed/Refractory Multiple Myeloma: Real-World Experience From the Myeloma CAR T Consortium https://pubmed.ncbi.nlm.nih.gov/36623248/ Incidence, Prognostic Impact and Clinical Outcomes of Renal Impairment In Patients With Multiple Myeloma: A Population-Based Registry https://pubmed.ncbi.nlm.nih.gov/31773154/ International Myeloma Working Group https://www.myeloma.org/international-myeloma-working-group IMWG Scientific and Working Committees https://www.myeloma.org/international-myeloma-working-group/imwg-scientific-working-committees
We have gone on vacation! But while we are off hiking and breathing, we are bringing you several episodes of a wonderful series we put out in 2021 at the start of this Matan podcasting venture. In this first episode our host, Dr. Yosefa Fogel Wruble sat down with Dr. Yael Ziegler to discuss several tools of biblical characterization and why they are significant for meaningful Tanakh study.
In this episode, Dr. Valentin Fuster discusses a major study on Loeys-Dietz syndrome (LDS), revealing that extra-aortic arterial aneurysms are both common and clinically significant across a broad vascular spectrum. The findings emphasize the need for comprehensive, head-to-pelvis imaging in LDS patients to detect and monitor potentially life-threatening aneurysms beyond the thoracic aorta.
Do you keep relapsing after treating candida, SIBO or other conditions? The culprit behind these never-ending cycles may be biofilms. In this episode, I'll explain how biofilms form, help you identify signs that you have them, and recommend the best antibiofilm agents. Tune in! Learn more about biofilms and improve your gut now! Reach out to our virtual clinic: https://drruscio.com/virtual-clinic/
Fr. Mike draws our attention to the descriptions of wisdom found in our readings for today and reflects on the beauty of wisdom's feminine nature. He also discusses the death of Antiochus Epiphanes and offers two perspectives on reconciling God's role in suffering. Today's readings are from 2 Maccabees 9, Wisdom 7-8, and Proverbs 25:1-3. For the complete reading plan, visit ascensionpress.com/bibleinayear. Please note: The Bible contains adult themes that may not be suitable for children - parental discretion is advised.