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Anger can affect many aspects of life, even as mundane as waiting in line at the grocery store. But what is anger, really?In this episode, Clinical Psychologists Mark Creamer and Dr Tony McHugh are joined by Senior Scientist at the Center for Military Psychiatry and Neuroscience at the Walter Reed Army Institute of Research (WRAIR), Dr Amy Adler, as they consider the definition of anger. During their conversation they explore its cognitive and behavioural components; its normality as a human emotion, and at what point it can be considered ‘problematic.'They share research findings about the relationship between anger and various mental and physical health issues; the enduring impacts it has on individuals in military service, and how anger plays into current diagnostic criteria. Stay tuned for two more episodes in this series featuring Mark Creamer and Tony McHugh discussing mental health and anger.Follow MHPN Presents to be alerted when they drop.Visit the MHPN website for episode host and guest bios, recommended resources and a self-directed CPD form.Share your comments, questions and feedback about A Conversation About… or any of MHPN's podcast series here: bit.ly/37FFMFM.
This week we will discuss M-RNA vaccines. Our guest is Thomas VanCott, PhD. Thomas VanCott is currently the Chief Scientific Officer for Combined Therapeutics, a Boston based biotech company developing targeted mRNA therapies. Prior to this he served as the Chief Technology and Strategy Officer for Catalent Cell & Gene Therapy, a global CDMO manufacturing viral vectors for gene and cell therapies as wells as plasmid DNA & mRNA platforms based in Baltimore, MD. He was responsible for strategically enhancing CMC services to meet the market demand of increasingly complex gene and cell therapy products as well as leading the product development and internal R&D teams. Prior to this, he was the CEO for 10 years at a Maryland-based CMO/CRO (ABL) where he was responsible for the strategic international growth of the company. He has been involved in biologics product development for over 25 years. He has a PhD in physical chemistry and started his career as a Captain in the US Army stationed at Walter Reed Army Institute of Research (WRAIR) studying and developing HIV vaccines for international deployment from initial construction through preclinical development, GMP manufacturing and clinical development. Vaccines help prevent infection by preparing the body to fight foreign invaders (such as bacteria, viruses, or other pathogens). All vaccines introduce into the body a harmless piece of a particular bacteria or virus, triggering an immune response. Most vaccines contain a weakened or dead bacteria or virus. However, scientists have developed a new type of vaccine that uses a molecule called messenger RNA (mRNA) rather than part of an actual bacteria or virus. Messenger RNA is a type of RNA that is necessary for protein production. Once cells finish making a protein, they quickly break down the mRNA. mRNA from vaccines does not enter the nucleus and does not alter DNA. mRNA vaccines work by introducing a piece of mRNA that corresponds to a viral protein, usually a small piece of a protein found on the virus's outer membrane. (Individuals who get an mRNA vaccine are not exposed to the virus, nor can they become infected with the virus by the vaccine.) By using this mRNA, cells can produce the viral protein. As part of a normal immune response, the immune system recognizes that the protein is foreign and produces specialized proteins called antibodies. Antibodies help protect the body against infection by recognizing individual viruses or other pathogens, attaching to them, and marking the pathogens for destruction. Once produced, antibodies remain in the body, even after the body has rid itself of the pathogen, so that the immune system can quickly respond if exposed again. If a person is exposed to a virus after receiving mRNA vaccination for it, antibodies can quickly recognize it, attach to it, and mark it for destruction before it can cause serious illness. Like all vaccines in the United States, mRNA vaccines require authorization or approval from the Food and Drug Administration (FDA) before they can be used. Currently vaccines for COVID-19, the disease caused by the SARS-CoV-2 coronavirus, are the only authorized or approved mRNA vaccines. These vaccines use mRNA that directs cells to produce copies of a protein on the outside of the coronavirus known as the “spike protein”. Researchers are studying how mRNA might be used to develop vaccines for additional diseases. (credits: Medline Plus)
Tia Lyles-Williams, D.Sc. is a Two-Time Life Science Start-Up Founder – Founder & CEO of LucasPye BIO, a Contract Development Manufacturing Organization (CDMO); and Founder & CEO of HelaPlex, the 1st Commercial Life Science Accelerator for Seed-Level Life Science Start-Ups and Virtual Biotechnology Companies. In fact, LucasPye BIO is a strategic partner of Thomas Jefferson University's Jefferson Institute for Bioprocessing (JIB). Dr. Lyles-Williams is the 1st African American Queer Woman to own and lead a biopharmaceutical manufacturing company – 68 years after the 1st African American Man, Dr. Percy Lavon Julian with his company, Julian Laboratories, Inc. in Chicago, IL. She received her Bachelor of Science in Biology from Howard University, Master of Science in Entertainment Business from Full Sail University, and a Master of Science in Regulatory Science from University Southern California. On May 12, 2022, Dr. Lyles-Williams was conferred as an Honorary Doctorate in The Sciences from the Sidney Kimmel Medical College at Thomas Jefferson University in Philadelphia, PA. Most recently, Dr. Lyles-Williams participated as a panelist at The White House discussion Biotechnology and the Bioeconomy in the U.S. via the U.S. White House Summit on Biotechnology and Biomanufacturing. Link: https://youtu.be/U2bdz5HE1zM Dr. Lyles-Williams has been working in the biotechnology / biopharmaceutical industry for 22+ years – including formerly interning at the National Institutes of Health (NIH) as well as a former contractor at Walter Reed Army Institute of Research (WRAIR in Silver Spring, MD). Her former employers include Human Genome Sciences, Inc. (now GSK) – Rockville, MD; Amgen, Inc. – Thousand Oaks, CA; Baxter BioScience (now Takeda) – Thousand Oaks, CA; Avid Bioservices – Tustin, CA; Lonza Pharma & Biotech – Portsmouth, NH; and Jazz Pharmaceuticals, PLC – Philadelphia, PA. Find Dr. Tia Online! https://www.linkedin.com/in/tia-l-596a484/ https://www.lucaspyebio.com/ If you're enjoying Entrepreneur's Enigma, please give us a review on the podcast directory of your choice. We're on all of them and these reviews really help others find the show. Also, if you're getting value from the show and want to buy me a coffee, go to the show notes to get the link to get me a coffee to keep me awake, while I work on bringing you more great episodes to your ears. → https://gmwd.us/buy-me-a-coffee Follow Seth Online: Seth | Digital Marketer (@s3th.me) • Instagram: Instagram.com/s3th.me Seth Goldstein | LinkedIn: LinkedIn.com/in/sethmgoldstein Seth on Mastodon: https://masto.ai/@phillycodehound Learn more about your ad choices. Visit megaphone.fm/adchoices
Leaders who have personally experienced the aftermath of a suicide-related event can provide important lessons and recommendations for military leadership and policymakers. This podcast executes a thematic analysis of interviews with leaders, chaplains, and behavioral health providers who responded to garrison suicide-related events and explores leader decision-making related to memorials, investigations, and readiness Click here to read the article. Keywords: suicide postvention, garrison, military leader, chaplain, behavioral, health provider Episode Transcript: Leader Perspectives on Managing Suicide-related Events in Garrison Stephanie Crider (Host) You're listening to Decisive Point, a US Army War College Press production focused on national security affairs. The views and opinions expressed in this podcast are those of the authors and are not necessarily those of the Department of the Army, the US Army War College, or any other agency of the US government. Decisive Point Welcomes Major Thomas H. Nassif and Captain George a Mesias, co-authors of "Leader Perspectives on Managing Suicide-related Events in Garrison” with Dr. Amy Adler. This article was featured in the Parameters Winter 2022–23 edition. Nassif, a research psychologist at the Walter Reed Army Institute of Research (WRAIR), serves as the Institute's lead on mindfulness training research efforts with the US Army War College and the US Army Training and Doctrine Command. He's also the principal investigator on a military suicide research grant funded by the congressionally directed medical research programs. Mesias is a licensed clinical social worker and researcher at WRAIR. He's advised commands and planned behavioral health operations across the Korean theater of operation and served as behavioral health officer for a Stryker Brigade. He is an Applied Suicide Intervention Skills Training master trainer and a graduate of the Army Social Work Child and Family Fellowship Program. Dr. Amy B. Adler is a clinical research psychologist and senior scientist at the Center for Military Psychiatry and Neuroscience at WRAIR. She's had numerous randomized trials with Army units, published more than 180 journal articles and chapters, and served as lead editor of Deployment Psychology and Anger at Work, both published by the American Psychological Association. Your article opens with, “In the last decade, suicide has become a leading cause of death for service members, claiming more lives than combat and transportation accidents.” This is a hard topic to ease into. What else do we need to know about service members and suicide for this article? MAJ Thomas H. Nassif Suicide is a difficult topic for a number of reasons. And many, if not all of us have been touched by it in some way, and the ripple effects across the unit and community when there's a suicide-related event. It's a really important topic, and there are many initiatives that the Army is engaged in that address risk factors and prevention. Our paper tackles a different part of the problem. you probably heard of prevention. What we're going to talk about today is postvention, in other words, what leaders do in the aftermath of a suicide-related event. First some terminology. So we define a suicide-related event as death by suicide, suicide attempt, or suicide intent. And by leader, we're referring to chaplains, behavior health providers, and unit leaders. And the leaders that we focused on in the article were chaplains, behavior health providers, and unit leaders. Although postvention has been studied in a deployed setting, we focused on garrison settings, which run the risk of being overlooked. CPT George A. Mesias This is Captain Mesias. I'm a licensed clinical social worker. As a social worker, I've served as a therapist for soldiers, and I've served as a behavioral health officer for a Brigade combat team. Suicide is an often-discussed topic due to ACE tra...
Dr. Jerome H. Kim, M.D., is the Director General of the International Vaccine Institute (IVI - https://www.ivi.int/), a nonprofit International Organization established in 1997 as an initiative of the United Nations Development Programme (UNDP), dedicated to the discovery, development and delivery of safe, effective and affordable vaccines for global public health. IVI is headquartered in Seoul and hosted by the Republic of Korea with 36 member countries and the WHO on its treaty. Dr. Kim served as the Principal Deputy and Chief of the Laboratory of Molecular Virology and Pathogenesis at Military HIV Research Program at the Walter Reed Army Institute of Research (WRAIR), in addition to being the Project Manager for the HIV Vaccines and Advanced Concepts Evaluation Project Management Offices, U.S. Army Medical Material Development Activity. Dr. Kim was also a Professor within the Division of Infectious Diseases of the Department of Medicine at the Uniformed Services University of the Health Sciences. From 2004 – 2009 he led the Army's Phase III HIV vaccine trial (RV144), the first demonstration that an HIV vaccine could protect against infection, as well as subsequent studies that identified laboratory correlates of protection and sequence changes in breakthrough HIV infections after vaccination. Dr. Kim graduated from the Yale University School of Medicine in 1984 and completed his training in Internal Medicine and fellowship in Infectious Diseases at Duke University Medical Center. In 2013 he received the John Maher Award for Research Excellence from the Department of Medicine, Uniformed Services University of the Health Sciences and throughout his career to date, Dr. Kim has authored over 200 publications.
Colonel Victor Suarez, currently serves as Commander (Chief Executive) of the 6th Medical Logistics Management Center (https://6mlmc.amedd.army.mil/), in Fort Detrick, Maryland (the U.S. Defense Department's only Medical Logistics Management Center ready to deploy in support of global and domestic operations) responsible for leading, organizing, equipping, training, maintaining, and sustaining unit subject matter expertise in medical materiel, medical maintenance and satellite communications support to the operational forces. Prior to this role, Colonel Suarez played an instrumental role as the Program Manager for the Moderna COVID-19 Vaccine at Operation Warp Speed (OWS) - a whole of government public/private partnership to rapidly deliver a safe and effective SARS-COV2 vaccine for the USA. Colonel Suarez has also served as Assistant Chief of Staff for Logistics for the US Army Regional Health Command-Atlantic managing the healthcare, PPE, lab diagnostics and medical maintenance supply chain for 14 direct reporting medical treatment facilities (medical centers, hospitals, clinics), was the Chief of Staff of the Walter Reed Army Institute of Research (WRAIR), U.S. DOD's largest biomedical research laboratory, and was the Joint Product Manager of the Joint Vaccine Acquisition Program (JVAP), a biodefense advanced development vaccine program. Colonel Suarez graduated from UCLA with a BS in Anthropology, holds a Master of Science in Health Services Administration from Central Michigan University, Senior Service College Fellow Graduation Certificate from The George Washington University - Milken Institute School of Public Health, and is Defense Acquisition Level III certified in Science and Technology Management, Program Management and Life Cycle Logistics Defense Acquisition University. He's also a graduate of the Tufts CSDD (Center for the Study of Drug Development) Postgraduate Course in Clinical Pharmacology, Drug Development and Regulation and the Cornell University Pharmaceutical Management Program. Colonel Suarez has served the U.S. in active military service, including a broad span of assignments from Airborne Infantry, Special Operations, Mechanized Infantry and Headquarters Department of the Army, including two combat tours as a Forward Support Medical Company Commander and Battalion Level Commander.
Everyone's working hard to get medical measures out there to defeat COVID. What is the Army doing, and how can families stay physically and mentally healthy while we wait for a solution? COL Deydre S. Teyhen, DPT, PhD, OCS, Commander, Walter Reed Army Institute of Research (WRAIR), joins us today for an update on the Army's vaccine effort, emphasizing safety throughout the development process. She describes how academia, industry and government have all come together to fight COVID-19, and how we will defeat it together as a team and as a community. Since mind and body are so intertwined, COL Teyhen also provides tips for relieving COVID-related stress arising from things like social isolation, too much family togetherness, and dealing with our emotions. Recommendations for future topics are welcome via email at podcast@ausa.org. Guest: Colonel Deydre S. Teyhen, Commander, Walter Reed Army Institute of Research Host: Patty Barron, AUSA's Director of Family Readiness Family Voices, a segment of AUSA's Army Matters Podcast, aims to connect Army families to speakers and issues that are important to their everyday lives. Resources: Walter Reed Army Institute of Research (WRAIR) Website: https://www.wrair.army.mil/ Facebook: @WRAIROfficial Twitter: @WRAIR U.S. Army Medical Research and Development Command (MRDC) Website: https://mrdc.amedd.army.mil/ Facebook/Twitter: @USAMRDC
Dr. Joseph Bellati is a Professor of Pediatrics and Microbiology and Immunology, and Director of the International Center for Interdisciplinary Studies of Immunology at Georgetown University Medical Center. Following the completion of his residency at the Children’s Hospital of Buffalo in 1961, he was accepted into a National Institutes of Health-supported postdoctoral fellowship in a developmental immunology training program at the University of Florida in 1961 under the direction of Richard T. Smith, MD, a pioneering pediatric immunologist and disciple of Robert A. Good, MD (1961-62) and later continued his postdoctoral studies as a research virologist at Walter Reed Army Institute of Research (WRAIR), Washington, D.C. Dr. Bellanti has focused a major investigative effort on antimicrobial research, evaluation of new vaccine strategies and developmental immunology. Together with other investigators, he has studied antibody and phagocytic cell function in the newborn human and in experimental model systems. Dr. Bellanti’s academic career has been nurtured by his previous research that has focused on the immunopathogenesis of infectious diseases, and the allergic and autoimmune disorders. Dr. Bellanti draws upon his pioneering experience as an established clinical investigator in the field of translational research in immunology.
Dr. Hailey Weerts, Walter Reed Army Hosp. - Soldier Health Not Old Better Show Food, Travel & Health, Interview Series Welcome to The Not Old Better Show, I'm Paul Vogelzang and this is episode #356. Today's show is brought to you by Travelan. As part of our Food & Travel Interview Series, today's show is for all of you, eager to learn the intricacies, details, and research behind effective prevention for travel-related diarrhea. In today's show, we'll be joined by Dr. Hailey Weerts, in her role as Research Scientist employed by The McConnell Group working in support of Walter Reed Army Institute of Research: WRAIR. Dr. Weerts is an Immunologist on a research team involved in the development and characterization of vaccines against Shigella. The team is currently engaged in the investigation of immune responses to Shigella vaccines in pre-clinical studies and human clinical trials. Today's interview with Dr. Weerts will focus on her team's research at Walter Reed Army Institute of Research, also know as WRAIR, pronounced RARE, as well as the nature of the bacteria Shigella, and it's vast impact, plus about the efficacy of Travelan, and the Immuron, maker of Travelan, technology platform. I should point out that Travelan is approved by regulatory agencies in Australia and Canada and is marketed as a dietary supplement in the US. Travelan has passed rigorous US Army tests of efficacy and treatment value. I think you'll value this interview with Dr. Hailey Weerts, and most importantly be introduced to the science and extensive research around the Travelan product. Please join me in welcoming to the Not Old Better Show, Dr. Hailey Weerts. Please check out Travelan here: https://www.amazon.com/dp/B01JOE7RGM For more information, links, resources, and details, please click here> https://www.travelanusa.com/ And, here> is a free scientific research paper on the efficacy of Travelan: https://www.immuron.com.au/assets/files/Travelan%20Scientific%20Review%20AU.pdf The Not Old Better Show, Talk About Better® https://notold-better.com
Careers in Army Medicine offer unparalleled opportunities to engage in exciting research with the potential to improve human health. As an infectious disease physician and researcher at Walter Reed Army Institute of Research (WRAIR), Col. Paige Waterman has been involved in a variety of clinical programs focused on improving and pioneering the practice of medicine. She discusses her interests in clinical medicine, what intrigued her about a career in the Army, and her experiences as an AMEDD officer.
Sleep is an area of research often overlooked, yet it impacts everyone from Soldiers to civilians in every walk of life. Ltc. Capaldi discusses the work the Walter Reed Army Institute of Research (WRAIR) is doing to better understand our sleep patterns and apply this research to improve training and care for Soldiers. He also talks about insights this research holds for our everyday lives, and shares interesting and even surprising findings from his studies.
In this episode, we speak with Ltc. Hinkle and Ltc. Tyner from the U.S. Army Multidrug Resistant Organism Repository and Surveillance Network (MRSN) about their research on drug-resistant organisms, a serious public health risk. Hear researchers at the Walter Reed Army Institute of Research (WRAIR) are expanding the Army’s capabilities to produce breakthrough therapies with worldwide potential.
In this episode, I interview Dr. Steve Jex, the director of the organizational and industrial psychology program at the University of Central Florida, and author of the book Thriving Under Stress (Oxford University Press). Dr. Jex shares his amazing experience and knowledge with us on the topic of leadership stress. More about Dr. Jex (from UCF faculty page) Steve M. Jex (Ph.D. 1988, Industrial/Organizational Psychology, University of South Florida) is a Professor of Psychology at University of Central Florida. He is also the Director of the Ph.D. Program in I/O Psychology. Prior to joining the faculty at UCF in 2017 he has held faculty positions at Central Michigan University, University of Wisconsin Oshkosh, and Bowling Green State University. In addition to his academic appointments, Dr. Jex has held Guest Scientist positions with the National Institute for Occupational Safety and Health (NIOSH), and Walter Reed Army Institute for Research (WRAIR). For the past 28 years his research has focused on stress in the workplace, particularly the role of individual differences in employee reactions to stressors. Most recently he has focused on the impact of various forms of interpersonal mistreatment on employee health and well-being. He has co-authored two books (with Tom Britt), including Organizational Psychology: A Scientist-Practitioner Approach (3rd Edition), and Thriving under stress: Harnessing the demands of the workplace.
U.S. Army Col. Nelson Michael, Ret., MD, PhD, Director, U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research (WRAIR), talks about the Army’s critical work on the RV144 trial in 2009, which showed that a preventive HIV vaccine was possible. Since this episode was recorded, the HVTN702 trial began in South Africa and is the first efficacy trial for an HIV vaccine in seven years.
Malaria is one of the biggest public health challenges in the world. We sat down with Ltc. James Moon, Director of Malaria Clinical Development at the Walter Reed Army Institute of Research (WRAIR), to learn more about the Army’s cutting-edge research through a robust clinical trial program that aims to identify vaccine candidates against malaria. He discusses the Army’s approach to tackling this global threat and takes listeners on a virtual audio tour of the clinical process behind this critical research.
U.S. Army Col. Stephen Thomas, MD, an infectious disease physician and vaccinologist, explains how the Walter Reed Army Institute of Research (WRAIR) identifies emerging threats like Zika and Ebola, and rapidly develops vaccines to combat these threats.
US Army Col. Christian Ockenhouse, director of the US Military Malaria Vaccine Program at the Walter Reed Army Institute of Research (WRAIR), will discuss WRAIR’s malaria efforts, which encompass vaccine research, drug development, and diagnostics.The Walter Reed Army Institute of Research is the premier biomedical research facility for the Department of Defense, focusing on the health and medical readiness of US military personnel while supporting global health efforts. WRAIR's portfolio includes the Center for Infectious Disease Research and Center for Military Psychiatry and Neuroscience. Walter Reed Army Institute of ResearchUS Army Medical Research and Materiel CommandNaval Medical Research Center's Malaria Research DepartmentPATH Malaria Vaccine InitiativeSeattle BiomedThe Bill and Melinda Gates FoundationThe appearance of advertising on this Web site, does not constitute endorsement by the Department of Defense, of the products or services advertised on this site.Read Transcript