Podcasts about immunologist

Send us a textWhat if beauty isn't something we chase, but something we cultivate from within? In this week's episode, Camille is joined by Dr. Ebru Karpuzoglu (EH-broo KAR-poo-ZOH-loo), an Immunologist trained in Molecular Medicine, founder of AveSeena, and author of Empire of Mirrors: Exposé of Beauty Untold.Together, they explore how science and self-care intertwine to empower women to redefine beauty on their own terms. You'll learn how inflammaging—the chronic, low-grade inflammation linked to aging—impacts both our skin and emotional health, and what small, science-backed rituals can help restore balance, confidence, and vitality.If you've ever struggled with burnout, self-image, or feeling disconnected from your reflection, this conversation will help you see beauty through a new, empowering lens.In this episode, you'll learn: The science behind “inflammaging” and what it means for women's health How emotional wellness and stress directly affect your skin Simple, daily rituals to calm inflammation and restore balance How to redefine beauty through confidence and authenticity What Dr. Ebru uncovered while writing Empire of Mirrors — and how we can reclaim our power from the beauty industryConnect with Dr. Ebru Karpuzoglu: Website: www.aveseena.com Book: Empire of Mirrors: Exposé of Beauty Untold (available wherever books are sold) Instagram: @aveseenaConnect with Camille: www.camillewalker.co Listen to more episodes of Call Me CEO Follow on Instagram: @camillewalker.coIf you loved this episode, please share it with a friend or leave a review — your support helps us reach more women who are ready to lead with clarity, confidence, and care.

Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Fei Li Kuang, MD, PhD, an allergist and immunologist, at Northwestern Medicine, about receiving two APFED HOPE on the Horizon Grants. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:50] Co-host Ryan Piansky introduces this episode, brought to you thanks to the support of Education Partners GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:14] Holly introduces today's topic, two APFED HOPE on the Horizon Pilot Grant Projects and today's guest, Fei Li Kuang, MD, PhD, an Assistant Professor in the Division of Allergy and Immunology at Northwestern University Feinberg School of Medicine in Chicago, Illinois.   [1:42] Dr. Kuang is a physician-scientist who takes care of patients with eosinophilic disorders and also performs laboratory research on these disorders in her lab, often using patient samples. Holly thanks Dr. Kuang for joining us.   [2:05] As a child, Dr. Kuang always wanted to be a scientist. She is so grateful to live out her childhood dream, and it's because of the amazing people who have supported her, most importantly, her parents.   [2:29] In graduate school, Dr. Kuang studied B cells. When she went on to do an allergy fellowship, she thought she would study B cells and care for patients with B cell problems. Instead, she fell in love with allergy and eosinophilic disorders.   [2:50] Dr. Kuang is here, in part, because of the different mentors she has had, and in large part, because of the patients she has met along the way.   [3:20] Dr. Kuang had the opportunity to work with Amy Klion at the NIH in a clinical trial to treat patients with a drug that gets rid of eosinophils. She says it was a dream come true after her training.   [4:02] She says she learned so much about eosinophils, their unusual biology, and the mystery behind what they are here for. She got hooked.   [4:15] Dr. Kuang thinks the patients you meet in a clinical trial in a special place like NIH occupy a space in your heart that makes you want to keep working on the subject area.   [4:34] Patients in a clinical trial have given up a bunch of their time to travel to Bethesda, Maryland. For the trial Dr. Kuang participated in as a Fellow, it was a good year of their time to come out and do it.   [4:47] Dr. Kuang felt there were so many interesting questions, from an intellectual point of view, but there was also a real need from patients with chronic conditions. It was a beautiful opportunity to marry scientists with physicians in training.   [5:36] Dr. Kuang shares some knowledge about eosinophils. They are white blood cells that are in all of us. They have little pink packages or granules that "jumped out" in the light microscope almost 200 years ago, when we first identified them.   [6:00] Dr. Kuang says that animals, dating back to reptiles, and different species of dolphins, all have eosinophils. A veterinary scientist, Dr. Nicole Stacy of the University of Florida, has taken photos of eosinophils from all these different species.   [6:21] They've been around for a long time. What are they good for? What we know is that they are associated with disease conditions, such as asthma and others, including leukemia. Those were the classic first studies of eosinophils.   [6:42] Now, we have a different mindset about eosinophils from work by the late James Lee at Mayo Clinic, Arizona.   [6:58] Dr. Kuang credits Dr. Lee with suggesting that eosinophils not just cause us problems but also help treat parasitic infections, maintain tissue homeostasis, help wound healing, and tissue repair. That's a new area we are beginning to appreciate.   [7:41] Dr. Kuang says we need to be open-minded that in some circumstances, eosinophils may be helpful or innocent. Now we have tools to start to understand some of that. We need to collect information from patients being treated with medicines.   [8:10] Ryan tells of being diagnosed as a kid. Doctors explained to him that eosinophils fight parasites, but in some people, they get confused and attack the esophagus. That's EoE. That was easy to understand, but he knew that the researchers knew more.   [8:53] Ryan is grateful to the patient population around eosinophilic esophagitis, and is proud of APFED's support of patients and caregivers with HOPE Grants. APFED has the HOPE on the Horizon Research Program, entirely funded by community donations.   [9:13] To date, APFED has directed more than $2 million toward eosinophilic disease research initiatives through various grant programs. As a patient advocacy organization, APFED works with fantastic researchers who submit innovative research ideas.   [9:32] These research ideas go through an extensive and competitive peer-review process, supported by researchers and clinicians in the APFED community.   [9:42] Today, we're going to discuss two different projects supported by HOPE Pilot Grants with Dr. Kuang.   [10:00] Dr. Kuang thinks there are two ways these grant programs are important to patients. One is advancing research by nurturing seedling investigators. Dr. Kuang got her first grant when she was a Fellow. It was an incredible opportunity.   [10:25] These grant programs also nurture seedling ideas that don't have enough evidence yet to garner the larger NIH grants, and so forth. There are other sources for grants: pharmaceutical companies. The grant programs are for seeds.   [10:49] Patients need to know that there are new things that are given some chance of being tested out. Research takes some time, and the FDA process of getting a drug approved is long.   [11:04] For the newly diagnosed patient, it can feel overwhelming. It feels like there's a loss of control. Sometimes, participating in something like APFED, being part of a community, gives back a sense of control that is lost when you're handed a diagnosis.   [11:45] For patients who have had it for a long time, when they participate in research and become engaged in organizations like APFED, they know they may not directly benefit today, they may benefit later, but they hope future patients will benefit.   [12:21] That gives them a sense of control and hope that things will be better for the next generation. We all want that, especially in medicine, in something that we don't have a very deep understanding of.   [12:58] Dr. Kuang received two HOPE Pilot Grants, one in 2018 and one in 2022. The first grant was awarded when she was a Fellow at the NIH.   [13:05] That first grant explored some effects of eosinophilic depletion of pathogenic lymphocytes in hypereosinophilic syndrome and overlaps with EGIDs. Ryan asks for a broad overview of that research.   [13:25] When Dr. Kuang was a Fellow at the NIH, they were doing a Phase 2 clinical trial, looking at "blowing up" eosinophils in patients who have a lot of them, hypereosinophilic syndrome patients.   [13:39] They included patients who had eosinophilic GI disease, often beyond the esophagus. They may have esophageal involvement, but sometimes their stomach is impacted, sometimes their large bowel is impacted, with related symptoms.   [13:57] What Dr. Kuang and the team noticed in the trial was that just within that little group of patients, there were people who did well, and people who did much better than before, but would have recurrent symptoms, and with no eosinophils in their GI tissues.    [14:16] The researchers wanted to know what was causing these problems for the patient. If you take eosinophils away, what other factors will impact the immune system of the patient, semi-long-term?   [14:32] Their focus was on these groups of patients who had different responses. They looked at the white blood cells that had been previously described as being the responsible, "bad" T cells that lead to eosinophils in the gut.   [14:49] They found that the patients who had recurrent flares of the disease had more of the bad T cells, and the patients who responded well and never complained again about symptoms did not.   [15:03] That allowed researchers to identify that there were subsets of patients with the disease that they were calling the same thing.   [15:18] Dr. Kuang says that work also led them to find that those cells were being reported in patients who had food allergies for which they needed an epinephrine auto-injector.   [15:27] The researchers were curious whether that was just a food allergy issue, or only applied if you had food allergies and eosinophilic GI disease. That HOPE project allowed them to do a pilot study to look at food allergy patients, too. They did, and published it.   [15:45] They published that in patients who have a food allergy and have these T cells, the insides of those cells make different messages for the immune system than the ones that the researchers had previously described.   [16:01] In looking for why there were differences in those responses, they accidentally found that there were differences inside these cells in a completely different disease, which also had these T cells.   [16:21] Dr. Kuang says that the finding was kind of a surprise. If they had found anything in the eosinophilic GI disease patients, that would have been good. They also looked at the epithelial cells and the structure of the GI lining.   [16:42] Even though there were no eosinophils in the GI lining in the patients who had been treated with a biologic that depleted eosinophils, their GI lining still looked like the GI lining of patients who had eosinophilic GI disease.   [16:55] Dr. Kuang asked what was creating those spots. Our gut lining sheds, so there should have been an opportunity for the GI lining to turn over and look new. Something was there, making signals to create these spots. They did a different publication on that.   [17:21] The data from the HOPE Pilot study allowed Dr. Kuang to apply for larger grants. It allowed her to propose to the company that made this drug, when they did the Phase 3 trial, to insert into that special study the study on eosinophilic GI disease.   [17:48] Do patients with eosinophilic GI disease do better or worse on this drug, and how do the T cells look in that trial? That HOPE Grant gave Dr. Kuang the data to ask the drug company to give her money to study it in an international cohort of patients.   [18:17] There were only 20 patients in that first NIH trial, who gave a year of their life, coming to NIH all the time. They continued to be in the study until the drug was approved for asthma.   [18:28] Dr. Kuang says the main reason the company did the Phase 3 trial, which is expensive, and the market share is not huge because it's a rare disease, is that two of the patients went to bat for this disease population.   [18:47] The two patients went and showed the business people what they looked like before, what the drug had done for them, and how their lives had changed. It wasn't the doctors or the great paper from the trial, but the patients who convinced the company.   [19:01] Dr. Kuang says she was so floored by that and moved by what they did for the community. She is grateful.   [19:24] Since the Phase 3 trial, Dr. Kuang and the other researchers realized they had not fully studied the eosinophils. They had studied them in part. They found differences in response. This inspired the second APFED HOPE Pilot Grant.   [21:19] In 2022, Dr. Kuang received a two-year APFED HOPE Pilot Grant to examine how blood eosinophils in Eosinophilic Gastrointestinal Diseases differ from those of other eosinophilic diseases and how T cells in EGIDs differ from those in food allergies.   [21:49] Dr. Kuang says normally, the biggest place of residence for eosinophils is the GI tract. That's where they are normally seen in people who do not have eosinophilic disorders.   [21:59] People who have eosinophilic disorders that attack other parts of the body, asthma, and rarely, the heart. Dr. Kuang was curious to know why one person and not the other?   [22:15] Patients who have eosinophilic GI disease often ask, How do you know this high level in the blood is not going to attack my heart or my lungs in the future? Dr. Kuang does not know.   [22:29] Dr. Kuang says, looking at the cohort at the NIH, that for many patients who have both GI organ involvement and some other space, when they first went to see a provider, their first complaint was a GI condition.   [22:54] If the doctor had only diagnosed a GI condition, nothing else, that would have been wrong. Those patients may not have been monitored as well. A third of the patients originally presented like that.   [23:11] What that meant was that we should be paying attention to patients who have GI disease who have lots of eosinophils in their blood. Moving forward, if there are new complaints, we need to investigate. We can't forget they have that.   [23:27] Dr. Kuang asks, Wouldn't it be great if we had a better tool than needing to wait? Wouldn't it be great if we had a biomarker that said the eosinophils have switched their target location and are going somewhere else?   [23:41] One way to do that is to take different groups of eosinophils and look for differences between those that never target the GI tract and those that do. In patients who have EoE, the eosinophils only target or cause problems in the esophagus.   [23:58] Are their eosinophils any different than those of a healthy person, with none of these conditions? That was the goal of that study.   [24:10] T cells are another type of white blood cell. They contain a memory of foreign things they have encountered, which allows them to glom onto flu, COVID, peanuts, pollen, that kind of thing. They remember.   [24:32] Dr. Kuang says they learned that T cells, at least in the mouse model, are required in the development of eosinophilic esophagitis. The mice in the old study, where mice were forced to develop EoE, did not get EoE if you removed their T cells.   [24:50] In the first APFED HOPE grant study, Dr. Kuang found T cells in the blood and tissue of both EGIDs and food allergy patients, but the insides of the T cells were different. The food allergy patients were children recruited by a pediatric allergist.   [25:19] In the second APFED HOPE grant study, at Northwestern, Dr. Kuang recruited her adult food allergy patients. That was a way to validate what they found in the first study and move further to better characterize those T cells in the two different diseases.   [25:47] Dr. Kuang says we're at a point where we've recruited a lot of people. She says it's amazing what people are willing to do. It's very humbling.   [26:06] Dr. Kuang's team in the lab is really great, too. To accommodate patients, they would see them after work, if that's what they had to do to isolate eosinophils. So they did that, and now they are in the process of analyzing that data. It's really exciting.   [26:28] What's exciting is that they are seeing results that show that eosinophilic GI disease patients have circulating eosinophils that are different from the eosinophils of people who don't have GI involvement, and from people who have EoE.   [26:46] The EoE patients have eosinophils different from those of healthy donors. Dr. Kuang says there's a lot of promise for perhaps unique signatures that could help define these conditions; maybe someday without biopsying, but that's a long time away.   [27:16] Dr. Kuang says they will focus on some candidate targets and try to recreate some of that in a dish with eosinophils from healthy people.   [27:26] What are the signals that lead eosinophils to do this, and can we translate that back to available drugs that target certain cytokines or other pathways, and maybe give some insight to develop drugs that target other pathways for these diseases?   [28:17] Ryan thinks it's exciting that this research is narrowing in on not only the different symptoms, but also how the eosinophils are acting differently in these populations.    [28:44] Dr. Kuang is super excited about this research. You could imagine that all eosinophils are the same, but you don't know until you look. When they looked, using the newest technology, they found there were differences.   [29:33] Dr. Kuang says it is thought that T cells respond to triggers. We don't think eosinophils have a memory for antigens. T cells do. That's one of their definitions. When T cells react to a trigger, they give out messages through cytokines or by delivery.   [30:20] Those are the messages that recruit eosinophils and other cells to come and stir up some trouble.   [30:28] In the mouse model, where you don't have the T cells, and you don't get eosinophilic esophagitis in the particular way they made it happen in a mouse, that middle messenger is gone, so the eosinophils don't know where to go.   [30:44] With drugs that take out eosinophils, you think that you've gotten rid of the cell that creates all the problems. It shouldn't matter what the message says because there's no cell there to cause the damage.   [30:58] What Dr. Kuang learned is that, at least in certain eosinophilic GI diseases, that's not true. You erase the eosinophils from the picture, but that message is still coming.   [31:10] Who's carrying out the orders? Or is that message maintaining the wall of epithelial cells in a certain way that we didn't appreciate because the eosinophils were also there?   [31:24] It's important to study both, because one is the messenger and the other is one of the actors. Whether all of the actions taken by eosinophils are bad, or maybe some of them were meant to be good, we have yet to learn.   [31:40] At the moment, we're using it as a marker for disease activity, and that may change in the future, as we learn more about the roles of these cells in the process.   [31:50] We have drugs now that target eosinophils and drugs that target T cells. Dr. Kuang thinks it's important to study both and to study the impact of these drugs on these cells.   [32:02] You could theoretically use these drugs to understand whether, if someone responds to it, what happens to these cells, and if someone doesn't respond to it, what happens to these cells, and how this disease manifests in this flavor of patients.   [32:54] Dr. Kuang says, Often in science, we take a model. We think this works this way. Then, if this works this way, we expect that if we remove this, these things should happen. We did that with the first clinical trial, with NIH patients.   [33:10] It didn't quite happen the way we thought, so we had to go looking for explanations. These were unusual setbacks. Sometimes you have unusual findings, like the food allergy part.   [33:24] When Dr. Kuang went to Northwestern, she saw different cohorts of patients than she saw at NIH. She saw people who were seen every day, which is a different spectrum than those who are selected to be enrolled in a study protocol at the NIH.   [33:42] That broadened her viewpoint. It's maybe not all food-triggered. They were seeing adults who'd never had food allergies or asthma their whole life, and they had eosinophilic esophagitis suddenly as a 50-year-old. There's a significant group of them.   [34:10] What Dr. Kuang learned and tries to be open-minded about is that where you train, what sorts of patients you see, really shape your viewpoint and thinking about the disease process and the management process.   [34:24] Dr. Kuang says she was so lucky to have experienced that at a quaternary care referral center like the NIH and at an academic center like Northwestern, where there are fantastic gastroenterologists who see so many of these patients.   [34:56] Dr. Kuang and an Allergy Fellow knew they were going to get a wonderful data set from the NIH patients they had recruited, so they thought they had better look deeply at what had been learned before with older technology, with mice and people.   [35:13] They decided to gather previous research, and that ultimately got published as an article. From that research, they learned that people did things in many different ways because there was no standard. They didn't know what the standard should be.   [35:28] Different things you do to try to get eosinophils out of tissue impact how they look, in terms of transcript, gene expression, and what messages they make to define themselves as an eosinophil.   [35:43] They also learned that because eosinophils are hard to work with, they die easily, and you can't freeze them and work on them the next day; you can introduce issues in there that have to be accounted for.   [35:59] They learned that as an eosinophil research community, they ought to come up with some standards so that they can compare future studies with each other. Dr. Kuang says it was impossible to compare the old studies that used different premises.   [36:50] Dr. Kuang says we need to be proactive in creating the datasets in a standard way so that we can compare and have a more fruitful and diverse community of data. It's hard to use the old data.   [37:57] Dr. Kuang says they get fresh blood from patients, and because eosinophils are finicky, they need to be analyzed within four hours, or preserved in a way to save whatever fragile molecules are to be studied.   [38:19] If you let it sit, it starts dying, so you won't have as many of them, and they start changing because they're not in the body. Dr. Kuang experimented with putting a tube of blood on the bench and checking it with the same test every two hours. It changes.   [38:38] Four hours is a standard to prevent the eosinophils from dying. Patients need treatment. If a patient is hospitalized and needs treatment, Dr. Kuang's team needs to be there to get a sample before treatment is started.   [39:03] The treatment impacts it, changing the situation. Much of the treatment, initially, is steroids. When you give lots of steroids, the eosinophils go away. It's no good to draw their blood then.   [39:27] Dr. Kuang also gets a urine sample. The granules of the eosinophils can get into the urine. As they study people with active disease, they want to capture granule proteins in the urine as a less invasive way to monitor activity in different disease states.   [40:04] The patient just needs to give Dr. Kuang either arm and a urine sample.   [41:04] Dr. Kuang explains, you can count your eosinophils after four hours, but to study them, they have different flags of different colors and shapes. Those colors and shapes may mean that it's an activated eosinophil, or they may have other meanings.   [41:41] Dr. Kuang focused on markers that look at whether it's going to spill its granules and some traditional markers of activation.     [41:50] Everyone chooses a different marker of activation. So they decided to look at as many as they could. One marker is not sufficient. They seem to be different in different conditions. The markers are on the surface; you need to analyze them right away.   [42:20] Then, Dr. Kuang breaks open the eosinophils and grabs the messenger RNA. They preserve it to do sequencing to read out the orders to see what this eosinophil is telling itself to make. RNA chops up messages.   [43:00] When you open an eosinophil, a protein you find is RNA, which chops up messages, destroying parts of the cell. You want to save the message. There's a brief time to analyze the eosinophil. Dr. Kuang works to preserve and read the message.   [44:04] Dr. Kuang hopes someday to run a tube of blood, look at the flags on the eosinophils, and say, "I think your eosinophilic GI disease is active," or "You have a kind of eosinophilic GI disease we need to monitor more frequently for organ damage."   [44:38] If another patient doesn't have those flags, Dr. Kuang could say, "I think the chances that you're going to have involvement elsewhere are low." That can give reassurance to folks who are worried.   [45:15] Dr. Kuang hopes that someday we can understand better why some people have food allergies vs. eosinophilic GI disease. They both have T cells, but the T cells have different packages inside with messages to deliver.   [45:34] Every day, Dr. Kuang has to tell patients she doesn't have that answer. Someday, she hopes she can tell a patient she does have that answer.   [46:35] Dr. Kuang tells about an NIH grant she's excited about and the patients she recruits after therapy, or elimination diets, to examine eosinophils and T cells, to see the impacts their treatments or diets have had on eosinophilic GI disease.   [47:18] Dr. Kuang believes there will be predictors of who will respond to an elimination diet and who will respond to steroid therapy. She hopes one day to have that, rather than going through rounds of six to eight weeks followed by a scope.   [47:34] If you have an elimination diet for six to eight weeks, every time you add back a food, you have to do a scope. Dr. Kuang says it would be great if you could be more precise ahead of time for therapy.   [47:48] Dr. Kuang says these wonderful drugs selectively take out parts of the pathway in the immune system. They provide real-life opportunities to ask, why is this important in human biology and the human immune system?   [48:15] Dr. Kuang finds the knowledge itself fascinating and useful. She hopes it informs how we choose future drugs or therapeutic avenues to get the best we can out of what we've learned, so we have more targeted ways of treating specific diseases.   [48:48] Ryan is grateful for all the research happening for the eosinophilic disease community and all the patients participating in the research. He asks Dr. Kuang how a patient can participate in research.   [49:12] There are lots of ways to be involved in research. Dr. Kuang says her patients come away from participating in research feeling good about having done it.   [49:22] Answer a survey, if that's what you have bandwidth for. Where therapies are changing, being a part of a community is good for the community, for the future, but it's good for you, too. It's healing in ways that are not steroids or biologics.   [49:58] Being part of a community is healing in ways we all need when we feel alone and bewildered. You're not alone.   [50:12] There are many ways to participate: APFED, CEGIR, individual institutions, and clinical trials. They all have different amounts of involvement. It's worthwhile to participate, not only for future patients but for yourself. They're fantastic!   [50:56] Dr. Kuang talks about the privilege as a physician of working with APFED and other organizations to do this work.   [51:09] Holly thanks Dr. Kuang for sharing all of this research and exciting information.   [51:25] Dr. Kuang is excited about what her group is doing and is hopeful. Besides showing up for this disease, we have to show up for research, in general, in this country. It's a dark time for NIH research funding.   [51:55] Dr. Kuang asks the young listeners who are thinking of choosing a field to see the potential and get into it, study this, and believe that there's going to be a future with a more nurturing research environment.   [52:36] Dr. Kuang would hate to lose generations of scientists. She says that once she was a little girl who was trying to be a scientist. Her parents had no connections with scientists or doctors, but she was able to get into research, and she thinks you can, too.   [53:48] As a graduate student, Ryan has always been interested in trying to improve things, and he sees hope on the horizon. He's very grateful to the APFED community for supporting these research HOPE Pilot Grants.   [54:17] Ryan is very grateful to Dr. Kuang for joining us today.   [54:22] For our listeners who want to learn more about eosinophilic disorders, we encourage you to visit apfed.org and check out the links in the show notes.   [54:28] If you're looking to find a specialist who treats eosinophilic disorders, we encourage you to use APFED's Specialist Finder at apfed.org/specialist.   [54:37] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections.   [54:57] Dr. Kuang thanks Ryan and Holly and says she enjoyed the conversation. Holly also thanks APFED's Education Partners GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Fei Li Kuang, MD, PhD, Allergist and Immunologist, Northwestern Medicine   Grants and publications discussed: Apfed.org/blog/apfed-announces-2018-hope-apfed-hope-pilot-grant-recipient/ Apfed.org/blog/fei-li-kuang-hope-pilot-grant-award/  Pubmed.ncbi.nlm.nih.gov/39213186/ Pubmed.ncbi.nlm.nih.gov/37487654/   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of GSK, Sanofi, Regeneron, and Takeda.   Tweetables:   "I think the patients that you meet in a clinical trial, especially in a special place like NIH, occupy a space in your heart — I don't mean to be all too emotional about this — that makes you want to keep working on the subject area." — Fei Li Kuang, MD, PhD   "When I was a Fellow at the NIH, we were doing a Phase 2 clinical trial, looking at, for want of a better word, "blowing up" eosinophils in patients who have a lot of them, hypereosinophilic syndrome patients." — Fei Li Kuang, MD, PhD   "We're at a point where we've recruited a lot of people. I've had patients drive from the northern part of Illinois … come down and give me blood. It's amazing what people want to do and are willing to do. It's very humbling, actually." — Fei Li Kuang, MD, PhD   "You erase the eosinophils from the picture, but that message is still coming. Who's carrying out the orders? Or is that message maintaining the wall of epithelial cells in a certain way that we didn't appreciate because the eosinophils were also there?" — Fei Li Kuang, MD, PhD   "We need to be proactive in creating the datasets in a standard way so that we can compare and have a more fruitful and diverse community of data." — Fei Li Kuang, MD, PhD   "I think it's worthwhile to participate [in a clinical trial], not only for the future people but for yourself." — Fei Li Kuang, MD, PhD   Guest Bio: Fei Li Kuang, MD, PhD, is currently an Assistant Professor in the Division of Allergy and Immunology at Northwestern University Feinberg School of Medicine in Chicago, IL. She is a graduate of the Albert Einstein College of Medicine Medical Scientist Training Program with both a PhD in Cell Biology/Immunology and an MD.  She completed her Internal Medicine Residency at Columbia University, New York Presbyterian Hospital in New York City, she did her Fellowship in Allergy and Immunology at the National Institute of Allergy and Infectious Disease (NIAID) in Bethesda, Maryland. She is a physician-scientist who takes care of patients with eosinophilic disorders and also performs laboratory research on these disorders in her lab, often using patient samples.

A Gluten Free Podcast Episode 211Today I reflect on five gluten free life lessons from 2025. It's been a great year! There's been heaps of takeaways, things I've reflected on and struggles and wins throughout the year. I wanted to share the five biggest things I've learnt and hopefully by sharing them it will help you in your own coeliac and gluten free journey. What we'll cover: * Reflecting on last week's episode with mucosal Immunologist and Coeliac Disease Researcher at James Cook University, Dr Paul Giacomin * My hopes for coeliac disease and the gluten free diet in the future * Touching on next year's content for A Gluten Free Podcast * Importance of remaining objective and doing out best to not judge others for how they navigate their own coeliac disease and gluten free journey * 5 gluten free lessons from 2025* Importance of keeping up to date with medical check ups * Coeliac disease antibodies not coming down despite adherence to a strict gluten free diet * My osteopenia and ADHD diagnoses  * Meal prepping and planning to save time, money and energy * Asking questions and finding options depending on the level of knowledge in shared gluten and gluten free kitchens * Importance of leaving reviews for good gluten free experiences at restaurants and cafes * Staying connected with the coeliac and gluten free community * Teaser of next week's episode Links Buy Gluten Free Express by Helen Tzouganatos *This is an Amazon affiliate link. We earn a small amount when you purchase this book with our code* Enter our gluten free Christmas giveaway boxEpisode with The Coeliac Connection Founder, Jo WynneHow We Can Improve Coeliac Disease & Gluten Free Education & Awareness in the Australian Hospitality Industry with NSW Food Authority CEO, Andrew Davies Holistic Health Coach & Founder of 'The Healthy Celiac', Belinda Whelan episode Join our Podcast Facebook group Episode with Dr Paul Giacomin Episode with Dr Vincent Ho at Campbelltown Hospital Coeliac Australia's advice on monitoring and follow-up of coeliac disease 

The Government is set to pilot a new digital age-verification system aimed at strengthening online protections for children. Minister for Communications Patrick O'Donovan says the tool will be vital in tackling harmful content and improving online safety. We discuss the implications with Fianna Fáil TD Malcolm Byrne, Social Democrats TD Sinead Gibney, and Adrian Weckler, Tech Editor with the Irish and Sunday Independent.Later, hospitals across the country tighten visitor restrictions as a new flu strain hits “fast and hard,” raising concerns about mounting pressure on the health system. Professor Christine Loscher, Immunologist at DCU, breaks down what this means for the weeks ahead. Hosted on Acast. See acast.com/privacy for more information.

A Gluten Free Podcast Episode 210My guest on today's episode is Mucosal Immunologist and Coeliac Disease Researcher at James Cook University, Dr Paul Giacomin. We'll talk about a study involving hookworms in the treatment for people with coeliac disease, the insights from this research and how these studies can be used to learn more about alternative treatments for coeliac disease in the future. What we'll cover: * Dr Giacomin's role at James Cook University and how he came to work in coeliac disease research * Dr Giacomin's background in working on ulcerative colitis and other inflammatory bowel diseases* How intestinal worms can play a role in our immune system and inflammation in our bodies * How the idea for hookworms in the treatment of coeliac disease came about * The positives and negatives of intestinal worms in our health * Australian trial of hookworms in the study of coeliac disease in 2008* The tolerance levels of participants in coeliac disease hookworms study in 2012 * Insights from the hookworms study and why a therapeutic follow up trial didn't happen * How hookworms can have a potential broad immune effect on other diseases and health issues * Where hookworms come from and how they are transferred to humans * Participants' experience of living with hookworms* When to visit your GP if you suspect a worm infection * How hookworms are boosting tolerance in the immune system and protection from gluten in people with coeliac disease * How hookworms could be turned into synthetic versions in the form of medications * Plans for future hookworms in the treatment for coeliac disease * Progressing hookworm treatment programs* How the findings of hookworm studies in coeliac disease be applied to IBD (ulcerative colitis, Crohn's disease, etc) * Triggers of autoimmune diseases * How to keep up to date with Dr Giacomin's research trials and get into contact with him Links Hookworms for the treatment of coeliac disease symptoms study Coeliac Australia article on Worms study Email Dr Paul Giacomin: paul.giacomin@jcu.edu.auJoin our podcast facebook group Email us: aglutenfreefamily@gmail.comThis podcast reflects personal experiences and is not medical advice. Please consult a qualified healthcare professional for individual guidance. Celiac Cruise - a 100% gluten free vacation cruise is setting sail on two Australian cruises in 2026: one to the South Pacific and the other to New Zealand. There'll of course be awesome 100% gluten free food onboard, heaps of fun stuff to do, educational talks and a community of people who understand each other. Buy your tickets here & see ya onboard gluten free fam! 

Find More Great Info From Dr. Melanie Matheu Here: SUBSTACK: https://lilscience.substack.com TIKTOK:https://www.tiktok.com/@laughterinlight YOUTUBE: https://www.youtube.com/@LaughterInLight Hawk talks with immunologist Dr. Melanie Matthew about the upcoming flu season and the devastating impact of RFK Jr as HHS Secretary. Australia experienced record-setting influenza deaths this year, with flu killing more people than COVID. The H3N2 variant mutated to evade vaccine protection, leading to unprecedented hospitalizations. Japan declared a flu epidemic five weeks early, and similar patterns are emerging in the United States.Dr. Matthew explains why flu vaccination remains critical despite mutations, reducing hospitalizations by 30-40% in adults and 70-75% in children. The conversation shifts to RFK Jr's anti-vaccine policies at HHS, where he claims no vaccine is safe and effective despite having zero background in immunology or pediatrics. His appointment, along with Marty Makary at FDA and Jay Bhattacharya at NIH, represents a complete rejection of scientific reality in favor of political ideology.The discussion covers RFK Jr's role in 88 child deaths in Samoa from measles, his vitamin A recommendations causing liver damage in Texas children, and how VAERS data is being misrepresented. Dr. Matthew details the exodus of top scientists from NIH, cancelled research grants, and terminated clinical trials that will kill patients. Forever chemicals (PFAS) are being approved for pesticides while vaccine research funding gets slashed.America faces losing measles elimination status, rising preventable disease deaths, and compromised pandemic preparedness. The CDC's COVID vaccine guidance for pregnant women has been offline for months despite evidence linking infection to preterm births and neurological damage. This administration prioritizes grift over public health, with consequences spanning decades. SUPPORT & CONNECT WITH HAWK- Support on Patreon: https://www.patreon.com/mdg650hawk- Support Hawk's Merch Store: https://hawkmerchstore.com- Connect on TikTok: https://www.tiktok.com/@hawkeyewhackamole- Connect on BlueSky: https://bsky.app/profile/mdg650hawk.bsky.social- Connect on YouTube: https://www.youtube.com/@hawkpodcasts ALL HAWK PODCASTS INFO- Additional Podcasts Available Here: https://www.hawkpodcasts.com- Listen to Hawk Podcasts On Your Favorite Platform:Spotify: https://spoti.fi/3RWeJfyApple Podcasts: https://apple.co/422GDuLYouTube: https://youtube.com/@hawkpodcastsiHeartRadio: https://ihr.fm/47vVBdPPandora: https://bit.ly/48COaTBSimplecast: https://hawk-droppings.simplecast.com- Hawk Podcasts RSS Feed: https://feeds.simplecast.com/pPVtxSNJ

In this episode of Product & Packaging Powerhouse, host Megan Young Gamble recaps her experience at Makeup in New York 2025, from day 1 and this episode focusing on day two themes of packaging innovation, sustainability, and beauty tech. She shares actionable insights from industry panels including advances in sustainable packaging (like APC Packaging's patented mono-material droppers and refillable solutions), compliance considerations, smart packaging, and the importance of consumer psychology. Startup brand Rebel Queen's all-in-one curly hair product is highlighted for its minimalistic approach, while expert Roberta Sironi provides a masterclass on mascara packaging, launching an academy for deeper industry education. Megan ties it all together with observations on tech (especially AI's growing role in beauty and packaging), and offers advice for brands considering trade shows, encouraging startups to attend for valuable connections and inspiration. Be sure to check out Day 1 Recap HERE. Access our other podcast episodes mentioned during the episodeInside MakeUp in New York: Day 1 Innovation and Tech” with Megan Young Gamble. Listen HerePackaging Design, Influence, & Integrity" with Vicki Strull, Founder, Vicki Strull Design. Listen HereThe Truth About Stress, Skincare, and Your Immune System” with Dr. Ebru Karpuzoglu, Immunologist and founder of AveSeena and ChicScience Labs. Listen HereRoundtable: Packaging, Plastics & Platforms toward Circular Economy” with Emily Anne Friedman (Recycled Plastics Editor, ICIS), Ryan Fox (Packaging Analyst, Bloomberg Intelligence) and Nicole Toole (Founder of ECGO.) Listen HereHow Connected Packaging Shapes Sustainability and Traceability” with John Dwyer, Smart Packaging Expert at Smurfit Westrock & Maurizio Carano, Innovation & Marketing Director IML @ MCC Label. Listen HereAffiliate & Other Links: [Megan Young Gamble Links][AFFILIATE] Ready to crank out your content in as little as 5 minutes? Use Castmagic, AI powered tool to take your content creation from overwhelmed to overjoyed by saving hours of developing content. Save 20 hours by Signing up today! https://get.castmagic.io/Megan [FREEBIE] Learn about “day in the life” of a Packaging Project Manager → Get our “Starter Packaging PM Freebie” [link] https://glc.ck.page/thestarterpackagingprojectmanager [FREEBIE] Access commonly referenced organizations and tools in ONE PLACE with our handy guide HERE [link] https://bit.ly/OSTPlay Subscribe & Access our Video Vault YouTube Channel [ link] https://bit.ly/GLConYouTubeJoin our Email List [link] https://glc.ck.page/55128ae04b Follow and Connect with Megan on LinkedIn [link] https://linkedin.com/in/megangambleLearn about GLC, Packaging & Project execution firm for CPG brands http://www.getlevelconsulting.comWork with Me @ GLC, Schedule Discovery Call https://calendly.com/getlevelconsulting/15-minute-insight-sessionGot a topic you'd love us to cover? Share your ideas here [link] https://bit.ly/ppptopicformContact details of Jennifer Lehto, Senior Business Development Manager at APC PackagingLinkedin - https://www.linkedin.com/in/jenniferlehtoEmail id - jenniserl@apcpackaging.comRoberta Sironi, Chief Commercial Officer at Pibiplast SpaLinkedin - https://www.linkedin.com/in/roberta-sironi-0636982/Pibiplast academy - https://pibiplast.com/certificationsQuotes and Hooks:  We've always been very conscious about our scalp health because you have to make sure your scalp is clean to help with promoting hair growth.Smart packaging gives each product their own digital passport telling consumers what it is, where it came from and what to do at the end of life.Everybody wants sustainable packaging, but the real question is: what does sustainability mean to you and your brand?Glass is heavier, costs more to ship, and is prone to breakage, so is it really deemed sustainable? Something to think about.I struggled for years to find the perfect curly hair product and I finally created it, an all-in-one that hydrates, defines, and controls frizz. (Bleema, Rebel Queen)Mascara is a really complex product, you need a lot of technicity to make the magic and make the product work. (Roberta Cerroni, Pibi Plast)AI is here to stay, and I use ChatGPT as my daily assistant all the time to help me think through things and shorten cycle times.Would I attend Makeup In New York again? Absolutely. Is it a trade show that I would recommend any company to attend? Absolutely.

Today's Headlines: Former FBI Director James Comey pled not guilty to charges of obstruction and making false statements, with his trial now set for January 5th. Meanwhile, Trump's picking new enemies, calling for Illinois Governor JB Pritzker and Chicago Mayor Brandon Johnson to be jailed for “failing to protect ICE officers.” Both fired back, with Johnson saying it's not the first time Trump's tried to have a Black man unjustly arrested. Adding to that authoritarian flavor, new data shows nearly a quarter of FBI agents are now focused primarily on immigration enforcement — a number that hits 40% in some major field offices. Donald Trump announced that Israel and Hamas have finally agreed on the first phase of their ceasefire plan — Israel will pull back troops, hostages will go home, and prisoners will walk free. Qatar and Hamas added that the deal also opens the gates for aid to enter Gaza. At the same time, his administration quietly inked an executive agreement giving Qatar near–NATO-level security guarantees — a move that normally requires Senate approval, but apparently we're skipping that part now. In economic news, gold prices just hit a record high of $4,000 an ounce — the strongest rally since 1979 — while the dollar is down more than 9% this year, signaling a crisis of confidence in U.S. institutions. A 29-year-old Florida man was arrested for starting the January wildfires that destroyed over 17,000 homes in Malibu and Palisades, killing 30 people. And to end on a rare uplifting note, 64-year-old immunologist Fred Ramsdell won the Nobel Prize in Medicine — learning the news only after returning from an off-the-grid Montana vacation. Truly the anti-Trump. Resources/Articles mentioned in this episode: NYT: Comey Pleads Not Guilty and Will Seek to Dismiss Charges as Vindictive Axios: Trump baselessly calls for Pritzker, Chicago mayor to be jailed WaPo: A quarter of FBI agents are assigned to immigration enforcement, per FBI data WSJ: Trump Says Middle East Deal Is ‘Very Close,' May Travel to Region This Week Axios: U.S. security guarantee for Qatar sparks jealousy and confusion Axios: Gold's rally signals investors' eroding trust in the U.S. AP News: Authorities charge man with sparking deadly January wildfire that leveled LA neighborhoods Wired:Scientist Who Was Offline 'Living His Best Life' Stunned by Nobel Prize Win Morning Announcements is produced by Sami Sage and edited by Grace Hernandez-Johnson Learn more about your ad choices. Visit megaphone.fm/adchoices

DR. Juanita Mora...Immunologist and spokesperson for the American Lung Asso on News Radio KKOBSee omnystudio.com/listener for privacy information.

In this episode of the Product & Packaging Powerhouse, host Megan Young Gamble sits down with Dr. Ebru Karpuzoglu, an immunologist, molecular medicine expert, wellness coach, and founder of AveSeena and ChicScience Labs. Dr. Ebru explains the critical impact of stress and inflammation, especially “inflammaging” on skin health, and why acute inflammation is necessary while chronic or persistent low-level inflammation is harmful. She shares her journey combining science with intentional daily rituals and discusses her focus on creating multitasking skincare products that address inflammatory issues, especially for busy women. Dr. Ebru also highlights the importance of compliance, GMPs (Good Manufacturing Practices) and not following fleeting beauty trends, urging new brands to focus on targeted needs and sound partnerships. The episode covers myths in the beauty industry (like “clean” meaning chemical-free), TikTok trends to avoid, and how packaging matters but real results keep customers loyal. There's also a fun sci-fi rapid-fire round at the end!Affiliate & Other Links: [Megan Young Gamble Links][AFFILIATE] Ready to crank out your content in as little as 5 minutes? Use Castmagic, AI powered tool to take your content creation from overwhelmed to overjoyed by saving hours of developing content. Save 20 hours by Signing up today! https://get.castmagic.io/Megan [FREEBIE] Learn about “day in the life” of a Packaging Project Manager → Get our “Starter Packaging PM Freebie” [link] https://glc.ck.page/thestarterpackagingprojectmanager [FREEBIE] Access commonly referenced organizations and tools in ONE PLACE with our handy guide HERE [link] https://bit.ly/OSTPlay Subscribe & Access our Video Vault YouTube Channel [ link] https://bit.ly/GLConYouTubeJoin our Email List [link] https://glc.ck.page/55128ae04b Follow and Connect with Megan on LinkedIn [link] https://linkedin.com/in/megangambleLearn about GLC, Packaging & Project execution firm for CPG brands http://www.getlevelconsulting.comWork with Me @ GLC, Schedule Discovery Call https://calendly.com/getlevelconsulting/15-minute-insight-sessionGot a topic you'd love us to cover? Share your ideas here [link] https://bit.ly/ppptopicform[Powerhouse Guest Dr Ebru's LINKS]LinkedIn: https://www.linkedin.com/in/ebrukarpuzoglu/Company Website: www.aveseena.comCompany Website: www.chicsciencelabs.com Additional Resource [Podcast] "MoCRA, Misconceptions and Regulatory Risk" - Ariana Farina, Regulatory Consultant @ Ariana Farina. Listen here Episode Quotes:.Don't follow the trends, find your niche, find a good partner, and be intentional.Clean doesn't mean chemical-free. Everything is a chemical, even waterEverything inside is mirroring outsideYou're an open system. Your skin is your outer layer, but it's designed to feel everything.If you don't have inflammation, you will die. Inflammation keeps us alive.Chronic stress induces inflammation, and you see it right away on your face and in how your body feels.Inflammaging is that silent, low-level inflammation that slowly makes you look tired and age faster.Science doesn't work against you, it works for you.Be ethical, be transparent. When you put your head on the pillow at night, you should know you did it right.

In this special Tick Boot Camp Podcast episode recorded live at Project Lab Coat during New York Fashion Week (NYFW), we sit down with Dr. Michal “Mikki” Caspi Tal, Principal Scientist in the Department of Biological Engineering at MIT and Associate Scientific Director of the MIT Center for Gynepathology Research. Dr. Tal is an immunologist and immunoengineer whose groundbreaking research focuses on the connections between infections and chronic diseases, including Lyme disease and long COVID. At her Tal Research Group lab, she studies why some people recover quickly after infection while others develop chronic illness, with a focus on the immune system's different responses in men and women. What You'll Learn in This Episode How Dr. Tal's lab uses mouse models of chronic Lyme and a large clinical study to take a deeper look at Lyme disease. Why some patients make a protective immune response while others develop catastrophic responses like dysautonomia, MCAS, gynecological issues, or clotting disorders. How her team is moving beyond “yes/no” antibody tests to create new biomarker diagnostics that can guide treatments. Why sex differences matter in chronic illness and why women are more likely to experience long-term symptoms after infection. How her research could lead to more personalized treatment approaches for Lyme disease patients by grouping individuals based on immune response patterns. What samples (blood, saliva, sweat, tissue) her team is collecting at MIT to uncover new insights into chronic Lyme disease. Why this research brings hope to Lyme patients who feel unseen and unheard. About Dr. Michal Caspi Tal Principal Scientist, MIT Department of Biological Engineering Associate Scientific Director, MIT Center for Gynepathology Research Focus areas: Lyme disease, long COVID, chronic inflammatory diseases, sex differences in immune response, predictive diagnostics Background: PhD in Immunobiology from Yale (mentored by Dr. Akiko Iwasaki), postdoctoral training at Stanford (Irving Weissman lab), infectious disease research leader at Stanford's Institute for Stem Cell Biology and Regenerative Medicine. Awards: NIH NIAID F31 and F32 Fellowships, Bay Area Lyme Foundation Emerging Leader Award About Project Lab Coat at New York Fashion Week Project Lab Coat was a groundbreaking event held on September 13, 2025, during New York Fashion Week (NYFW). The show brought together prominent celebrities, researchers, doctors, and advocates who were invited to walk the runway to spotlight Lyme disease and raise funds for Lyme disease research. For the first time, the global visibility of NYFW was used to highlight one of the fastest-growing infectious diseases in the world. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen, together with Dr. Tal, walked the runway at Project Lab Coat, joining leaders from medicine, science, entertainment, and advocacy. Project Lab Coat demonstrated the power of mainstream platforms to bring awareness, credibility, and resources to the fight against Lyme disease. Why This Episode Matters For too long, chronic Lyme patients have been told their symptoms are “all in their head.” Dr. Tal's work at MIT proves otherwise by measuring the real biological differences in immune system responses. This research not only validates patients' experiences but also charts a course toward better diagnostics, clinical trials, and personalized treatments.

9/18/25: Immunologist Dr. Jonathan Bayuk: covid & flu shots & RFK, Jr. Gazette & Gfld Recorder Ex Ed Dan Crowlwy: covering elections & bullets in Belchertown. Rabbah Riqi Kosovske: Jewish High Holidays & the War in Gaza. Nhmptn Jazz Festival Pres Ruth Griggs w/ the extraordinary Zaccai Curtis.

Warner Carr, MD, Allergist and Immunologist at the Allergy and Asthma Associates of Southern California, discusses the mastocytosis control test and its implications for physicians.

Pop Culture Green Room co-host Blair sits down with Dr. Ebru Karpuzoglu, a brilliant immunologist and founder of AveSeena, to talk about how science can make your skincare smarter.We chat about:Why your skin's immune health matters just as much as your skincare routine, how she developed her skin care line AveSeena, and how she went from the research lab to creating a clean beauty brand that's gentle, effective, and actually feels amazing to use.AveSeena website: https://www.aveseena.com/AveSeena on InstagramAveSeena on Facebook#AveSeena #CleanBeauty #SkincareTips #GlowingSkin #HealthySkin #ScienceBasedBeauty #SkinCareRoutine #SensitiveSkinCare #BeautyChat #thepopculturegreenroom #fyp #explorepage #popculturepodcast

Today's guest is Dr. Ebru, a dynamic force in the world of skincare. With a background in molecular medicine, immunology, and cosmetic chemistry, she created her skincare line, AveSeena, from the ground up. She was one of the first to connect inflammation, “inflammaging,” the immune system, and the skin microbiome in the development of her products. Beyond her scientific expertise, Dr. Ebru brings an upbeat energy and a wealth of valuable insights that you won't want to miss.

Professor Luke O'Neill, Immunologist at Trinity College Dublin and Newstalk regular joins Kieran to place his favourite book on The Hard Shoulder Bookshelf!

Pat Fitzgerald-Bocarsly moved from California to Boston and then settled with her husband in New Jersey where she and he both serve in academics at Rutgers and Princeton (in that order). Three adult children, 6 grandkids and a life of adventure and religion and successes in many areas of life. You will enjoy meeting this provost of Rutgers with much more to say about her worries and her hopes for the future. Historical marker includes the First Crusade, Boeing, and Versace and Twitter.Support the showThanks for listening. Please share the pod with your mates, and feel free to comment right here! Write to Bob on his email -- bobmendo@AOL.comLink to https://www.facebook.com/profile.php?id=100078996765315 on Facebook. Bobs Your Uncle features the opinions of Bob Mendelsohn and any of his guests.To financially support the podcast, go to the Patreon site and choose Gold, Silver or Bronze levels. Thanks for that! https://www.patreon.com/BobsYourUncle To read Bob's 1999 autobiography, click this link https://bit.ly/StoryBob To see photos of any of Bob's guests, they are all on an album on his Flickr site click here: https://www.flickr.com/photos/bobmendo/albums/72177720296857670

An immunologist giving evidence at the inquiry into the government's Covid-19 response, has been questioned on claims the debate around mRNA vaccines was shut down during the pandemic. Reporter Lucy Xia has more.

The Allergy Truth: What's Really Making You Sick? Dr. Tania Elliott, MD – Board-Certified Allergist, Immunologist & Internal  In this eye-opening episode, Hurricane H welcomes Dr. Tania Elliott, a nationally recognized board-certified allergist, immunologist, and internal medicine physician. Known for her expertise in diagnosing and managing complex allergic and immune-related conditions, Dr. Elliott has been a trusted medical voice on platforms like NBC, CBS, and The Dr. Oz Show. She combines clinical experience with clear, compassionate communication to help patients and audiences understand their bodies better. Together, we uncover the truth behind one of today's most underestimated health issues: allergies. From seasonal sneezing fits to food intolerance, unexplained fatigue, skin flare-ups, and respiratory distress — could allergies be the hidden culprit? Dr. Elliott sheds light on what's really making people sick, how our immune systems are reacting to modern environments, and what you can do to take control of your health.

The Allergy Truth: What's Really Making You Sick? Dr. Tania Elliott, MD – Board-Certified Allergist, Immunologist & Internal  In this eye-opening episode, Hurricane H welcomes Dr. Tania Elliott, a nationally recognized board-certified allergist, immunologist, and internal medicine physician. Known for her expertise in diagnosing and managing complex allergic and immune-related conditions, Dr. Elliott has been a trusted medical voice on platforms like NBC, CBS, and The Dr. Oz Show. She combines clinical experience with clear, compassionate communication to help patients and audiences understand their bodies better. Together, we uncover the truth behind one of today's most underestimated health issues: allergies. From seasonal sneezing fits to food intolerance, unexplained fatigue, skin flare-ups, and respiratory distress — could allergies be the hidden culprit? Dr. Elliott sheds light on what's really making people sick, how our immune systems are reacting to modern environments, and what you can do to take control of your health.

Cases of Measles are on the rise globally, and anecdotal evidence from early childhood providers here would suggest that far fewer parents are vaccinating their children.With reports of a suspected case of measles in a Dublin creche this week, creche owners are calling on the Government to offer better guidance and policy on how to deal with this…Joining Kieran to discuss is Elaine Dunne from the Federation of Early Childhood Providers Professor Luke O'Neill, Immunologist at Trinity College...

Description: Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Dr. John Accarino, an allergist and immunologist at Massachusetts General Hospital and Mass General for Children, on the topic of immunology support for eosinophilic esophagitis (EoE). Dr. Accarino shares his experiences as a person living with food allergies, allergic asthma, peanut allergy, and eosinophilic esophagitis. He tells how his experiences help him in his work with patients. Dr. Accarino shares some education on a variety of allergy mechanisms and the treatments that mitigate them. Disclaimer: The information provided in this podcast is designed to support, not replace the relationship that exists between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:49] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, GSK, Sanofi, and Regeneron. Ryan introduces co-host Holly Knotowicz.   [1:14] Holly introduces today's topic, immunology support for eosinophilic esophagitis (EoE), and introduces today's guest, Dr. John Accarino, an allergist and immunologist at Massachusetts General Hospital. Holly welcomes Dr. Accarino to Real Talk.   [1:49] Holly notes that Dr. Accarino is her allergist and immunologist.   [2:03] Dr. Accarino works at Massachusetts General Hospital and Mass General for Children. Allergy and Immunology is a field where he can see pediatrics and adults. Originally trained in pediatrics, now Dr. Accarino sees patients of all ages.   [2:23] Dr. Accarino grew up with allergies. He has experienced food allergies since he was young, along with allergic asthma, and some eczema, which he grew out of. Later in life, he was diagnosed with eosinophilic esophagitis. He talks with his patients about his experiences.   [2:47] Dr. Accarino also does research on drug allergies in the context of certain drug interactions that involve eosinophils.    [3:06] When Holly was referred to Dr. Accarino, it was for multiple sclerosis (MS). He told her, “It looks like you have EoE. I have EoE.” It was a huge relief to Holly not to have to explain EoE to her doctor.   [3:41] Some patients start to explain their EoE to Dr. Accarino, and he assures them he understands where they're coming from. Sometimes, he has to be careful not to think everyone has his symptoms, as there is a large spectrum of presentations.   [4:26] Dr. Accarino wasn't diagnosed with EoE until he was in his allergy fellowship, after he suspected it when he had a food impaction at a steakhouse at a graduation party from his pediatric residency. He tried to manage the EoE with lifestyle changes.   [5:39] Dr. Accarino didn't often go to see a doctor during residency, but he realized it was probably a good time to get an endoscopy.   [5:52] Holly shares how she was also diagnosed as a clinical fellow. She was subbing for someone on the GEDP team at Children's Hospital in Colorado. Listening to all the patients, she realized, “This sounds a little bit like me … What is going on?”   [6:23] Even with his medical background, it took Dr. Accarino some time to decide to get the endoscopy and biopsies. You or your doctor have to have a high level of suspicion to realize this isn't just reflux. Food doesn't get stuck in every person's throat.   [7:01] Thinking back, Dr. Accarino remembers an instance as a child when a dry muffin got stuck in his throat. He stayed calm and waited for it to pass. He thought it was normal.   [7:39] He drank a lot of water and chewed his food a lot. Those are markers of potential esophageal inflammation.   [8:20] Different groups have different management strategies for EoE. Dietary management, topical steroids, biologics. A subgroup of people with EoE are responsive to proton pump inhibitors (PPIs). Finding the best management strategy is a work in progress.   [8:53] With pediatric patients, the parents control the diet, and the children eat what is prepared. He notes that with adult patients, sometimes they let foods slip through.   [9:10] If you want to do a single-food elimination diet with dairy, there's a lot of dairy in the American diet. Dr. Accarino tried eliminating dairy and wheat, but he still had persistent eosinophils with dietary elimination.   [9:24] Dr. Accarino then tried PPIs. To know if you have PPI-responsive EoE, you might do twice-daily omeprazole at a significant dose. Have the endoscopy after a few weeks pass and see if the eosinophils are still present in the biopsy.   [9:59] Dr. Accarino did that recently and still has the eosinophils. He plans to talk to his gastroenterologist about considering dupilumab, but he feels that he can mitigate his subjective day-to-day experience of symptoms with dietary elimination and PPIs.    [10:24] If you still have the presence of eosinophils on biopsy, there's still inflammation happening. In the long term, you still have to worry about fibrosis and narrowing.    [10:34] The last treatment Dr. Accarino tried was as a research participant in a study for dissolvable fluticasone. He received either the medication or a placebo; he doesn't know which.   [11:01] To stay in the study, he had to journal and report his symptoms regularly. He didn't have enough symptoms to stay in the study. They were looking for a baseline to see how it changed with either the placebo or the medication.   [11:20] In research, you have to have a baseline to start, and then you want to see improvement, plus or minus. With EoE, it's difficult. You have the biopsy and eosinophils, but there's a large spectrum of symptoms that people may experience.   [12:40] Holly appreciates Dr. Accarino's unique perspective as a doctor with EoE who has experienced various treatments and diets. He understands the concerns of his patients.   [12:43] Dr. Accarino says even taking a twice-daily PPI or other medication is difficult for a lot of people, and that's the most simple of these therapies.   [13:06] Dr. Accarino wants to validate everyone's experience in terms of how difficult it is to treat this disorder, how it may present in different ways, and how there may be a delay in diagnosis.   [13:16] This isn't IgE-mediated immediate food allergy, where you eat a food and may have swelling within minutes; you may have flushing or hives. That's very clear. With EoE, it's a different mechanism; in many cases, there is a delay.   [14:37] Allergy, in general, is under the purview of clinical immunology. Dr. Accarino is allergic to peanuts and has an  IgE-mediated immediate reaction to them. If he eats a peanut, he has symptoms within minutes. He could have anaphylaxis. As a result, he carries an epinephrine auto-injector.   [15:01] If Dr. Accarino has a skin test, it will be positive for peanut. He has IgE antibodies to peanuts. He also has oral allergy syndrome where the body mistakes certain fruits, vegetables, or nuts with certain tree pollens or grass pollens.   [15:23] Oral allergy syndrome is usually a lower-risk condition where it's a less-stable protein that once cooked might not produce any symptoms. If it's raw when you consume it, you may have oral itching, a bit of throat discomfort, or tongue itching. [15:54] Your stomach acid breaks it down so it doesn't get into your bloodstream and you shouldn't have a systemic reaction.   [16:01] If Dr. Accarino eats a peanut, his stomach acid doesn't break down the high-risk, stable peanut protein, it gets into his bloodstream, and he can have a systemic anaphylactic reaction.   [16:20] Chronic EoE symptoms can present with something like a food impaction, or bad reflux or belly pain, and nausea. The reaction may not be immediate. It may be progressive over days or weeks.   [16:38] FIRE is an interesting condition that takes some time to narrow down. It's an immediate response of the esophagus, but we don't think it's histamine-mediated.   [16:56] We don't know, exactly, the mechanism but it's in people with eosinophilic esophagitis. They feel differently, and there would be different specific food triggers.   [17:11]  It took some time to figure out what was going on. Dr. Accarino felt like he had a lump in his throat, then a lump in his chest, nausea, and belly pain. It felt like a slow progression of EoE symptoms, and it was from specific food triggers, in his case.   [17:30] In some of the FIRE literature, they looked at banana and avocado. For Dr. Accarino, it took a couple of exposures to protein bars and milk protein whey isolate, specific to protein bars he had multiple times, until he figured out that was the trigger.   [17:50] Another protein whey isolate that Dr. Accarino scooped as a powder and made into a shake also led to FIRE.   [17:55] It took that event for Dr. Accarino to figure out it wasn't just a flareup of EoE or reflux but some trigger that caused this response that wasn't anaphylaxis but may be due to the recruitment of eosinophils or some immediate process not well understood.   [18:18] FIRE is going to be very hard to research. How would we figure this out? Would we bring someone in and do an endoscopy immediately and see what happens? There's a lot of descriptive data and case series.   [18:32] Dr. Accarino has had experiences when he knew it wasn't an immediate anaphylactic reaction, oral allergy, or reflux. He asked what else it could be in the context of EoE. When he looked at different case series, that's the presentation he had.   [19:17] Dr. Accarino acknowledges that having personal experience with FIRE, oral allergies, and IgE-mediated allergies, on top of EoE, has influenced his work as a medical professional. He can share anecdotes with patients as he explains the available testing.   [19:39] Dr. Accarino says a lot of immunology and allergy is explaining the diagnostic tools and management strategies we have and what we think is going on.   [19:50] The immune system is infinitely complex, and a lot of the practice is making a digestible analogy, not just in the context of allergic conditions but also everything with the immune system. There are so many cells doing so many different things.   [20:04] Dr. Accarino explains false positives in testing. He has positive scratch tests for peanuts, cashews, and almonds, which shows he has IgE for each of them. He is allergic to peanuts, but he can eat cashews and almonds. Those are false positives.    [20:56] When a scratch test is negative for immediate food allergy, it's a powerful predictive tool. But you may get false positives. How positive is it? There might be room for more discussion.   [21:10] There may be more hesitation for people who do large panels of food testing without any history of reacting to any foods.   [21:31] Some people have EoE triggered by milk or wheat but have negative skin tests. That doesn't mean they aren't triggered by these foods. The skin test is an IgE histamine mast cell mechanism, not for eosinophils, which are other immune cells.   [21:58] We go down these steps of thinking about diagnostic triggers and eventually treatment for those immediate symptoms mentioned for EoE.   [22:09] Dr. Accarino doesn't expect FIRE to be responsive to epinephrine. He doesn't have to stabilize the mast cells. It's a chronic disease that's flaring up. You treat it with a chronic type of treatment.   [24:10] Dr. Accarino says that for a doctor, immunology is rewarding, interesting, and complex, but it's intimidating until you get your foothold and see patients and clinical experiences.   [25:14] A lot of medical students and residents are a little fearful of immunology. They might not think about it too much. Dr. Accarino loves to talk about it and think about it. He can't think of anything more complex in terms of systems within our body.   [25:37] Ryan comments on his experiences with IgE-mediated food allergies, some environmental allergies that he has no idea how they work, and EoE, which he believes he has a good grasp on.   [25:55] Ryan imagines that having a physician with a good understanding of the immune system and also personal experience would be helpful for a patient with multiple allergic conditions.   [26:13] Dr. Accarino sees a large overlap of seasonal or year-round environmental allergies and EoE. There are some studies that show that endoscopies on patients with EoE may change at different times of the year if they have underlying seasonal allergies.   [26:33] Some people who have food allergies also have EoE or other eosinophilic disorders. Some discussions with them may be about blood tests that detect eosinophils in the bloodstream versus biopsies of the esophagus, stomach, or colon.   [27:15] It's thinking about what tests are available, what they tell us, and how to use them to predict the next steps, things like dietary changes or for immediate food allergy, considering challenges versus full avoidance. Each test has its pluses and minuses.   [27:35] People like a clear test, and they like an easy fix, but sometimes there's a lot of nuanced conversation of shared decision-making and trying things in a supervised setting.   [27:57] Holly speaks as a patient of the investigative testing Dr. Acarino is doing with her immune system trying to figure it out along with her MS and EoE.   [28:14] Dr. Accarino says the words immune system, immunity, and inflammation are used a lot in talking about foods. Dr. Accarino uses the framework of the immune system trying to help you.   [28:42] Sometimes, instead of making helpful antibodies to things like vaccines or viruses, that give you protection, the immune system makes antibodies that attack a certain organ or your joints.   [29:02] Dr. Accarino thinks of treatments that suppress the immune system in certain ways. Some treatments cool down the populations of many different immune cells. Oral steroids and prednisone are used for many conditions for autoimmune flares.    [29:29] Oral steroids, in the long term, may lead to weight gain, bone density changes, and diabetes. The big push for many diseases is toward non-steroidal biologics to target specific cells that cause disease.   [29:59] For Crohn's disease, a specific monoclonal antibody is used to target TNF-alpha molecules and blocks that inflammation pathway.   [30:14] For EoE, dupilumab, a specifically designed antibody, blocks a specific receptor in a specific pathway so the immune system doesn't have to be shut down and the patient doesn't have the side effects of steroids. It's a targeted therapy.   [30:32] What you see in commercials for injectable medications are large, designed antibodies that, if you took them in a pill form, your stomach acid would break down and digest. So they are injections and infusions that go directly into the bloodstream.   [31:22] Medications that end in -mab are monoclonal antibodies. They are very large molecules that would not be stable in stomach acid.   [32:09] Dr. Accarino talks of eosinophil normal function and aberrant function. IgE-mediated reactions are usually related to mast cells, a type of immune cell that shouldn't be in the bloodstream.   [32:54] Dr. Accarino can do a CBC with differential to see the number of white blood cells and the number of red blood cells. The differential of white blood cells will include neutrophils, lymphocytes, and eosinophils. It shouldn't show mast cells.   [33:19] If you have mast cells in your bloodstream, that's mastocytosis, a different problem. Mast cells live in your skin, in your gut, and around your blood vessels. They're full of granules like histamine and tryptase.   [33:38] Dr. Accarino explains how mast cells release their contents and how he would treat the resulting swelling or itch with an antihistamine or epinephrine. Epinephrine treats systemic reactions and stabilizes the mast cells.   [34:16] Mast cells have many receptors and may be triggered by many things other than IgE. This is a conversation Dr. Accarino has with patients who have chronic hives unrelated to any foods.   [34:29] Some people get hives from non-steroidal anti-inflammatory drugs NSAIDs. Some get hives from vancomycin. Some get hives when the temperature changes, from tight clothing, or from IV contrast. It's not an IgE-mediated mechanism, but it's still mast cells being degranulated.   [35:45] Dr. Accarino says people see hives and they think allergy. But, like EoE, it doesn't involve histamine. There can be hives that aren't related to allergies. This can be idiopathic urticaria or spontaneous urticaria.   [36:04] Sometimes, when switching from a day shift to a night shift, hormonal changes will trigger hives. Sometimes, the stress of having a family member in the hospital will cause hives. An accumulation of triggers can lead to mast cell degranulation.   [36:38] There are many ways that allergy can have different mechanisms and treatments, with different cells involved. There are different molecules that cause symptoms and manifestations.   [36:50] Navigating that and understanding what might be going on can give people a sense of reassurance. The biggest fear is a life-threatening allergic reaction. People will read about fatal anaphylaxis and wonder if it will happen to them with their condition.   [37:16] Sometimes, thinking of the cells involved and the pathways may give a level of reassurance that this may not be the same thing that they read about.   [37:28] Ryan thanks Dr. Accarino for joining us today.   [37:37] Dr. Accarino says it was nice to reflect on things and to go through different scenarios and experiences he has gone through. It was nice to have the opportunity to share them with Ryan, Holly, and all the listeners.   [37:57] For our listeners who would like to learn more about eosinophilic disorders, including EoE, please visit APFED.org and check out the links in the show notes.   [38:06] If you're looking to find a specialist who treats eosinophilic disorders, we encourage you to use APFED's Specialist Finder at APFED.org/specialist.   [38:15] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at APFED.org/connections.   [38:25] Ryan thanks Dr. Accarino for joining us today for this fun conversation. Holly also thanks APFED's Education Partners Bristol Myers Squibb, GSK, Sanofi, and Regeneron for supporting this episode.   Mentioned in This Episode: Dr. John Accarino, MD, Allergist and Immunologist at Massachusetts General Hospital and Mass General for Children Episode 034: Food-Induced Response and Eosinophilic Esophagitis   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, GSK, Sanofi, and Regeneron.   Tweetables:   “Allergy and immunology is a field where I can see pediatrics and adults. I was originally trained in pediatrics, but now I see all ages, from infants up until older adults.” — Dr. John Accarino   “Part of the conversation sometimes is trying not to overly bias myself, where I say, ‘Oh, this is my experience.' … Like many diseases, there's a large spectrum of presentations, … different symptoms that people have.” — Dr. John Accarino   “We don't think [Food-Induced Response in Eosinophilic Esophagitis is] histamine-mediated. We don't know exactly the mechanism, but it's in people with eosinophilic esophagitis. They feel differently, and there would be different specific food triggers. It took some time to figure out that was going on.” — Dr. John Accarino   “When a scratch test is negative for immediate food allergy, it's a very powerful predictive tool. But there are times that you may get false positives. How positive is it? There might be room for more discussion.” — Dr. John Accarino   “There are a lot of ways that allergy can have different mechanisms and different treatments, with different cells involved.” — Dr. John Accarino

In this episode of The Cognitive Revolution, Professor Derya Unutmaz, a biomedical scientist and human immunologist at the Jackson Laboratory, discusses his groundbreaking research in aging and cancer immunotherapy. As a ChatGPT Pro grant awardee, Derya provides insights into the integration of AI with biomedical sciences, emphasizing how advanced AI models are transforming hypothesis generation, data analysis, and scientific discovery. He also covers his early passion for computers and programming, the inspiration he derived from Ray Kurzweil's work, and how AI is democratizing science by enabling even young researchers to make significant contributions. Derya outlines his vision for a future with ASI, discussing potential societal impacts, the need for regulatory AI models, and the promise of a golden age where diseases are cured, aging is reversed, and resource scarcity is a thing of the past. Finally, he dreams about the long-term future, imagining a life of exploration and discovery across the cosmos. SPONSORS: SafeBase: SafeBase is the leading trust-centered platform for enterprise security. Streamline workflows, automate questionnaire responses, and integrate with tools like Slack and Salesforce to eliminate friction in the review process. With rich analytics and customizable settings, SafeBase scales to complex use cases while showcasing security's impact on deal acceleration. Trusted by companies like OpenAI, SafeBase ensures value in just 16 days post-launch. Learn more at https://safebase.io/podcast Oracle Cloud Infrastructure (OCI): Oracle's next-generation cloud platform delivers blazing-fast AI and ML performance with 50% less for compute and 80% less for outbound networking compared to other cloud providers. OCI powers industry leaders like Vodafone and Thomson Reuters with secure infrastructure and application development capabilities. New U.S. customers can get their cloud bill cut in half by switching to OCI before March 31, 2024 at https://oracle.com/cognitive Shopify: Shopify is revolutionizing online selling with its market-leading checkout system and robust API ecosystem. Its exclusive library of cutting-edge AI apps empowers e-commerce businesses to thrive in a competitive market. Cognitive Revolution listeners can try Shopify for just $1 per month at https://shopify.com/cognitive NetSuite: Over 41,000 businesses trust NetSuite by Oracle, the #1 cloud ERP, to future-proof their operations. With a unified platform for accounting, financial management, inventory, and HR, NetSuite provides real-time insights and forecasting to help you make quick, informed decisions. Whether you're earning millions or hundreds of millions, NetSuite empowers you to tackle challenges and seize opportunities. Download the free CFO's guide to AI and machine learning at https://netsuite.com/cognitive RECOMMENDED PODCAST: Second Opinion. Join Christina Farr, Ash Zenooz and Luba Greenwood as they bring influential entrepreneurs, experts and investors into the ring for candid conversations at the frontlines of healthcare and digital health every week. Spotify: https://open.spotify.com/show/0A8NwQE976s32zdBbZw6bv Apple: https://podcasts.apple.com/us/podcast/second-opinion-with-christina-farr-ash-zenooz-md-luba/id1759267211 YouTube: https://www.youtube.com/@SecondOpinionwithChristinaFarr

A new part of the immune system has been discovered by scientists who say it is a goldmine of potential antibiotics. The team behind the study have shown that a part of the body known to recycle proteins has a secret mode that can produce bacteria-killing chemicals. Immunologist and Professor Annie Curtis from the RCSI joins us.

In this episode of the Veterinary Cancer Pioneers Podcast, host Dr. Rachel Venable welcomes Dr. Mark Mamula, an immunologist and professor at Yale University School of Medicine, to discuss his groundbreaking work in canine cancer immunotherapy. Dr. Mamula shares how his background in autoimmune diseases led him to develop an experimental vaccine targeting EGFR and HER2 proteins in dogs with cancer. He explains the science behind this therapy, its clinical trial progress, and its potential to improve survival outcomes for cancers such as osteosarcoma and hemangiosarcoma. They also explore the challenges of bringing new therapies to veterinary medicine, the role of combination treatments, and the importance of accessible, cost-effective options for pet owners. Tune in for an insightful conversation on the evolving landscape of canine cancer treatment and the promising future of immunotherapy.

Dr Mark Dykewicz- Allergy and Immunology, Internal Medicine SSM Health SLUCare Physician Group, joins Megan Lynch as The Food and Drug Administration this week upgraded a food recall for Lay's Potato chips to the highest risk level.

Send us a textClickbait headlines, shady supplements, and sketchy policies—oh my! Enter Dr. Andrea Love, an immunologist and all-around impressive human.Frustrated by medical misconceptions, Andrea founded Immunologic with a mission to replace fear with curiosity and equip people with critical thinking skills.Medical organizations and safety or science agencies each have distinct roles, but their flexibility is often shaped by government policies. To navigate their guidance, rely on 2-3 solid, reputable (and relevant) resources—trusting just one source is like building a table with only one leg: it won't hold up.Research doesn't happen overnight. It's a marathon, not a TikTok trend. And as demographics represented become more overall present, it takes time for that to reflect. With the wave of attention to menopause in the media, women are the primary target of the wild west of unregulated supplements. Dr. Love warns about “Hormone hacks”. These claims are red flags built for sales, not science.Providers are in the trenches; how can they help patients survive this predatory landscape?By walking people through data (not fear) and translating science into—as Dr. Love bluntly puts it—something a 4th grader can understand.Some experts overuse jargon or discredit others. Don't get caught up in the Huberman Hype and be critical of red flags: conflicts of interest, excessive jargon, and acting like the authority on everything.Remember: Real experts know their limits—and yours. I had to cut this one short so you can soak up this wealth of information. Stay tuned for Part 2 of this interview next week. What's Inside:Medical misconceptions in the media.Who to trust in the sea of medical orgs, providers, safety orgs, and science communicators?Red Flags in the media and supplement industryGetting critical and understanding science and research.It can feel like everywhere you look there are big, bold medical claims! How can YOU solve this huge problem you didn't even know you had TODAY!? Are you guilty of trusting anyone with a PhD using big fancy words? How has this episode informed you on moving forward with science literacy? Let me know on Insta!Mentioned In This Episode:Andrea C. Love, PhD (@dr.andrealove) on Instagram Dr. Andrea LoveJen Gunter (@drjengunter) on InstagramJen — The Eco WellDanielle Shine (@danielleshine.dietitian) on InstagramDr Michelle Wong - Beauty Science (@labmuffinbeautyscience) on InstagramFit Feels Good (@oonaghduncan) on Instagraminfo@fitfeelsgood.com 

Dr Denis Bouboulis, an allergist and immunologist from the US, has been diagnosing and treating PANS PANDAS for nearly 20 years. He talks about the "wild card" of Covid and how Long Covid could be linked to underlying vector-borne infections, such as Lyme disease. In the States, there is more awareness and testing around Lyme and co than in the UK, and it certainly made me think about what could be missing from our children's treatment - especially those who do not seem to get significantly better or frequently relapse. He also discusses how short-term antibiotics to treat PANS/PANDAS is a "false narrative" and how long-term treatment is key for recovery. Although based in the States, he works via telemedicine across the world. Here he is on Linkedin https://www.linkedin.com/in/dr-denis-bouboulis/recent-activity/all/

Have you ever wondered how our body fights off infection and disease? It's a pretty cool process. Our guest, Dr. Namita Gandi, is an immunologist and she is going to explain the secret weapon that your immune system posseses to keep you healthy.   #sciencepodcast #sciencepodcastforkids #sciencecareeers #stem #stemcareers #stempodcastforkids #womeninstem #podcast Every episode of this award-winning science podcast for kids takes you behind the scenes of a scientist, engineer, or expert's daily job. Packed with fun facts, intriguing information, and lots of laughs, this podcast aims to educate as well as inspire.  The best part is that each episode gives our listeners a challenge to learn more. This week's challenge is to think about this: Think about a piece of fruit. How is it different from the inside and the outside?  Find more information on our website: www.solveitsciencepodcastforkids.com (https://solveitsciencepodcastforkids.com/)  Follow us on: Facebook @ kidssolve (https://www.facebook.com/KidsSolve) Instagram @kidssolve (https://www.instagram.com/kidssolve/) X @kidssolve (https://x.com/KidsSolve)  

Dr. Timothy Buckey, MD, MBE, discusses how medical ethics impact every patient encounter and offers practical advice on how to implement into clinical practice. (November 13, 2024)

 Today we have a fantastic returning guest, Clinical Nutritionist, Author, and Aloe Life founder, Karen Masterson Koch. Karen spent decades counseling patients in medical clinics. Karen's internship was at the Livingston Clinic, with the world-renowned Immunologist, Dr. Virginia Livingston, M.D.The topic is a good one – addressing pain in the body and the relationship to autoimmunity and more - including how health, ALOE have been helpful, and in our opinion Aloe Life is a great place to start feeling better and getting healthier or add it to any existing health program- for even better results!The fact of life is that all people will experience pain, it's a signal that something's not quite right and needs addressing. A type of SOS to take “health action first, to solve the pain issue”, not just blindly taking a Drug or over the counter, that temporarily covers it up or attempts to.There are different types of pain for sure yet the tips we share are truly universal.Go to www.aloelife.com for a store locator (to find a store near you) or to read more on health today or enter health20 at check out for 20% OFF. When calling, tell the Aloe Life team 1-800-414-ALOE you heard the show to get the extra handouts and discounts to support Digestion and Body Health, even great articles on Healthier Weight for 2024 too.Aloe Life is offering a BIG 50% DISCOUNT on their Certified Organic Daily Greens in tablets or powder (for a smoothie or tasty mixed in water). 1 scoop = 3 servings of veggies!

Host: Dr. Morgan McLeod, Asst. Professor of Pediatrics and Internal Medicine at the University of Mississippi Medical Center and Dr. Charles Grogan, Immunologist at UMMC.Topic: Our last show with Dr. Grogan on allergies was a hit, so we've welcomed him back to talk some more about medicines, triggers, and myths surrounding those pesky allergens. Send your questions or comments to: kids@mpbonline.org. Hosted on Acast. See acast.com/privacy for more information.

This is a free preview of a paid episode. To hear more, visit chrisryan.substack.comShawn Kubli is an American immunologist and surfer, currently land-locked in Toronto, Ontario. Working in the biotech industry for Treadwell Therapeutics, his research group develops living drugs – cell therapy – that harness the intrinsic power of the immune system to fight cancer. Shawn's academic background in evolutionary genetics and ecology shape …

Research scientists are equipping a vaccine with bits of proteins that redirect the immune system's efforts to specifically fight cancer. The vaccine aims to prevent cancer tumors from returning, as relapsing cancer is often more aggressive and difficult to treat. The latest research also seeks to understand why some cancer tumors evade the body's immune response. Featured experts are Dr. Keith Knutson, Immunologist and Cancer Vaccine Researcher at Mayo Clinic; Dr. Saranya Chumsri, Hematologist at Mayo Clinic​; and Dr. Nora Disis, Director of the Institute of Translational Health Science and the Center for Translational Medicine in Women's Health at University of Washington.

President Joe Biden has posted on social media that he believes it's in the best interest of the country to drop out, endorsing his Vice President Kamala Harris as his replacement. And In case you missed it, new research has found traces of toxic metals present in tampons from a range of brands. Before we sound the alarm and boycott tampons completely, we're turning to an expert to find out just how worried we should actually be. Spoiler alert: less than you think.  THE END BITS  Subscribe to Mamamia GET IN TOUCH Share your story, feedback, or dilemma! Send us a voice note or email us at podcast@mamamia.com.au and one of our Podcast Producers will come back to you ASAP. CONTACT US Got a topic you'd like us to cover? Send us an email at thequicky@mamamia.com.au CREDITS Host: Claire Murphy  With thanks to:  Dr Andrea Love, Immunologist and Microbiologist Producer: Claire Murphy  Senior Producer: Taylah StranoAudio Producer: Thom LionBecome a Mamamia subscriber: https://www.mamamia.com.au/subscribeSee omnystudio.com/listener for privacy information.

In this episode, we discuss the Dave Smith  @PartOfTheProblem  Chris Cuomo debate on  @VALUETAINMENT  , our predictions for the first presidential debate (see if they came true!) and more!! If you're enjoying the content, please like, subscribe, and comment! Please consider supporting the show! https://anchor.fm/worldxppodcast/support A cancer immunologist by training, Dr. Christopher Nirschl received his PhD from the Johns Hopkins School of Medicine in Immunology in 2015, and completed a postdoctoral fellowship at the Brigham and Women's Hospital in association with Harvard Medical School. He has been studying the interactions between cancer and the immune system for over a decade, and is also one of the inventors of the anti-TIGIT antibody ASP8374/PTZ-201 which is currently in clinical trials. Currently, Dr. Nirschl is an Immunologist at Werewolf Therapeutics in Massachusetts, where he lives with his wife and three children. Find his book, "What the Heck Is A Clinical Trial?", here - https://www.amazon.com/What-Heck-Clinical-Trial-Where-ebook/dp/B09QKG37T7 ______________________ Follow us! @worldxppodcast Instagram - https://bit.ly/3eoBwyr @worldxppodcast Twitter - https://bit.ly/2Oa7Bzm Spotify - http://spoti.fi/3sZAUTG Anchor - http://bit.ly/3qGeaH7 YouTube - http://bit.ly/3rxDvUL #patrickbetdavid #valuetainment #chriscuomo #davesmith #debate #trump #biden #freedom #immunology #covid #fauci #clinicaltrials #immunologist #author #published #life #lifeexperience #politicalnews #unitedstates #rogan #twitterfiles #podcastshow #longformpodcast #longformpodcast #podcasts #podcaster #newpodcast #podcastshow #podcasting #newshow #worldxppodcast --- Support this podcast: https://podcasters.spotify.com/pod/show/worldxppodcast/support

MSNBC's Ari Melber hosts "The Beat" on Tuesday, June 18 and reports on the lead-up to the first presidential debate of the 2024 election. Plus, Dr. Anthony Fauci joins for a special "Summit Series" interview. Chai Komanduri and Judge John Jones III join.

Immunologist & Vaccinologist, Dr. Robert Malone, MD, gives an expose on his extensive background in vaccine development from his significant contribution to the invention of mRNA technology to his involvement in the real life ongoing case about the injury cover-up from the MMR vaccine, portrayed in the film Protocol 7. Hear first hand why he believes gain-of-function research is one of the biggest threats to humanity.

An update on the current bird flu outbreak: it's still infecting wild birds, mammals and now several farmworkers in the United States. The virus does not appear to be transmitted between humans, but can we prevent further spread? And what are public health officials doing to contain it? Immunologist and virologist Rick Bright has been studying the bird flu for decades and tells Dr. Sanjay Gupta why he thinks more action is needed and who he thinks should be leading the charge. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Does you or your child suffer from food allergies? What are some breakthrough treatments that are on the horizon for food allergies, allergy and asthma? In this episode, Dr. Sarah is joined by Dr. Lauren Fill, a Pediatric and Adult Allergist and Immunologist, who will have the answer to these questions! Dr. Lauren Fill will talk about a new treatment approved for 1 year olds and older who suffer from multiple food allergies, oral immunotherapy, and more to improve quality of life!

Dr Charles B. Simone.  I am an Internist, a  Medical Oncologist, a Radiation Oncologist, and an Immunologist, trained at the Cleveland Clinic, the National Cancer Institute, and the University of Pennsylvania. Dr. Simone begins by letting us know that the virus was created on purpose and the DOD created the vaccine and then it was sold to Big Pharma. This was planned false flag to remove the President of the US. The cures have always existed but Big Pharma has kept it from the people. Now the people are learning that they do exist and that the Big Pharma and the Gov has been trying to hide from us.

To give to the Behind Greatness podcast, please visit here: https://behindgreatness.org. As a charity, tax receipts are issued to donors.  Thanks for joining us at behind Greatness. We sit down with Dr. Garry Nolan at his home in California. Garry is an Immunologist, an academic, an inventor and patent holder and a business executive. He also holds the Chair in the Department of Pathology at Stanford University School of Medicine. We pack this conversation with Garry's practice on focusing on the data to provide the conversation piece with other scientists and the public. We talk about Garry's personal experiences when he was younger and how they serve as fuel to his scientific inquiry. He elaborates on the importance for him in hiding his long term intent behind a cloak of real science. We hear about his research in a Harvard lab on the basal ganglia, prompted by earlier work done with Kit Green and high functioning remote viewers and intuition. We learn from him about doing science best with asking the Zen question - so that the answer will always move you forward. And, we hear a refreshing perspective on speculation of the non-human intelligence question and that “something behind the scenes”. As a life-long question-maker, he also shares with us the type of person he honours and why. Why? Because ‘why' is the answer. That's why.   Garry, Bio: https://med.stanford.edu/profiles/garry-nolan SOL Foundation: https://thesolfoundation.org/ Youtube: SOL Foundation Talk : https://www.youtube.com/watch?v=7UW1jyN2o8A Interview with Ross Coulthart: https://youtu.be/XR0JtbuLhPo?si=OHvvhH4PoJcK1OUT SALT Talk: https://youtu.be/e2DqdOw6Uy4?si=TgmtKiYBNRoW96pd X: @garrynolan See episode with Diana Pasulka (ep 142). Garry is also “James” in Diana's book American Cosmic

Episode 6 : From "No-Nut" Schools to EpiPens 101: Dr. Magdalena Berger, Clinical Allergist & Immunologist Unpacks Allergy Myths and Gives You The Tools to be an Allergy NinjaDISCLAMER >>>>>>    The Ditch Lab Coat podcast serves solely for general informational purposes and does not serve as a substitute for professional medical services such as medicine or nursing. It does not establish a doctor/patient relationship, and the use of information from the podcast or linked materials is at the user's own risk. The content does not aim to replace professional medical advice, diagnosis, or treatment, and users should promptly seek guidance from healthcare professionals for any medical conditions.                                                  >>>>>> The expressed opinions belong solely to the hosts and guests, and they do not necessarily reflect the views or opinions of the Hospitals, Clinics, Universities, or any other organization associated with the host or guests.                                                                                  Disclosures: Ditch The Lab Coat podcast is produced by (Podkind.co) and is independent of Dr. Bonta's teaching and research roles at McMaster University, Temerty Faculty of Medicine and Queens University. Welcome back to "Ditch the Labcoat," with me, Dr. Mark Bonta, and today we're diving into the complex world of allergies. Our guest, Dr. Magdalena Berger, brings her expertise on managing allergies in children, clarifies myths about EpiPen usage, and illuminates the murky waters of food allergy protocols. Expect personal tales, life-saving tips on handling anaphylactic shocks, and insights into global allergy trends.Whether you're a concerned parent or just curious about the immune system's quirks, this episode is packed with invaluable knowledge. So tune in as we tackle the science and skepticism of allergies head-on. Let's get started.00:00 Family medicine in crisis, need more providers.03:15 Internal medicine involves diagnosing, treating complex illnesses.06:17 Relevant roles in education discussing allergies and immunology.10:55 Concern over lack of access to allergist.14:46 Confirm food allergies through allergist office challenge.17:17 Clear diagnosis of food reactions requires thorough testing.21:40 Oral immunotherapy for food allergies and tolerance.23:04 Early introduction of allergenic foods needs caution.28:05 Hygiene hypothesis: overactive immune system from cleanliness.30:18 Dairy allergy and anaphylaxis: Can it happen?34:38 Maternal diet impact on baby's allergies summarized.37:49 Specific protein in milk can cause allergies.39:50 Deciding to probe or maintain relationships courteously.43:47 School has EpiPens for kids with allergies.45:28 Risk mitigation for allergies during unsupervised activities.51:34 Check expiration date, clear liquid means good.54:36 Podcast covers allergy; impact on parents.57:42 Ensure good working order, anticipate potential situations.59:05 Exciting updates and feedback for digital lab.

Host: Dr. Morgan McLeod, Asst. Professor of Pediatrics and Internal Medicine at the University of Mississippi Medical Center and Dr. Charles Grogan, Immunologist at UMMC.Topic: AllergiesSend your questions or comments to: kids@mpbonline.org. Hosted on Acast. See acast.com/privacy for more information.

Please join us and Dr. Joseph Forester, DO as we discuss his work as an Allergist & Immunologist at Cullman Regional in Cullman, AL. Dr. Forester specializes in the diagnosis and treatment of all forms of allergic disorders, asthma, and primary immunodeficiencies for patients of all ages. You can subscribe to the Better Health now podcast wherever you listen, follow us on Youtube @cullmanregionalmedicalcenter for the full length video, or visit the Cullman Regional Facebook page to stay up to date with new episodes as they are released. 

FREEDOM - LIBERTY - HAPPINESS SUPPORT DOC MALIK To make sure you don't miss any episodes please subscribe to either: The paid Spotify subscription here: ⁠https://podcasters.spotify.com/pod/show/docmalik/subscribe The paid Substack subscription here: ⁠https://docmalik.substack.com/subscribe About this conversation: Professor Dolores Cahill was a Professor of Translational Science at UCD School of Medicine, University College Dublin. Dolores has over 25 years of expertise in high-throughput protein array, antibody array, proteomics technology development, automation and their biomedical applications, including in biomarker discovery, diagnostics and personalised medicine. Dolores has published over a hundred peer-reviewed research papers, and been invited to numerous international scientific meetings as a keynote speaker, however, the mainstream media simply describe her as "an anti-vaccine and anti-mask campaigner". The real Dolores Cahill is a Scientist, Immunologist, Inventor, Innovator and Fracking awesome Freedom Fighter. Dolores from the outset of the plandemic called out the scam and unscientific measures being introduced and warned of the dangers of the experimental gene modifying shots. In this conversation we talked about The Law, the fraudulent legal system and agents of the system that deny us all of our inalienable rights. I didn't know where this conversation was going to go, but I am so glad we had it. An incredible woman, intelligent and brave and prepared to lose it all to do the right thing. IMPORTANT NOTICE Following my cancellation for standing up for medical ethics and freedom, my surgical career has been ruined. I am now totally dependent on the support of my listeners, YOU. If you value my podcasts, please support the show so that I can continue to speak up by choosing one or both of the following options - ⁠Buy me a coffee⁠ If you want to make a one-off donation. Join my Substack To access additional content, you can upgrade to paid from just £5.50 a month Doc Malik Merch Store⁠ Check out my amazing freedom merch To sponsor the Doc Malik Podcast contact us at ⁠hello@docmalik.com⁠  About Doc Malik: Orthopaedic surgeon Ahmad Malik is on a journey of discovery when it comes to health and wellness. Through honest conversations with captivating individuals, Ahmad explores an array of topics that profoundly impact our well-being and health. You can follow us on social media, we are on the following platforms: ⁠Twitter Ahmad⁠ | ⁠Twitter Podcast⁠ | ⁠Instagram Ahmad⁠ | ⁠Instagram Podcast

In the latest Simply Fit Podcast episode, Elliot interviews Dr. Julie Wendt, a triple board-certified allergist-immunologist and author specializing in allergies and intolerances. The episode covers the distinctions between food intolerances and allergies, offering a masterclass on understanding and managing them. Dr. Wendt delves into the differences between food allergies and other common allergies like dust, fur, and hay fever. Listeners can expect insights on feeding a large family with high-quality foods and tips on navigating environmental toxins. The episode also touches on topics such as allergy treatment, intolerance solutions, probiotic regimens, and the impact of stress and lack of sleep on gut health.

Dr. Andrea Love is an Immunologist and co-host of Unbiased Science Podcast. She is also the Director of the American Lyme Disease Foundation (ALDF). For this episode, she joined the show to talk about how alternative dietary approaches often reach a point where they become ideological and "cult like" versus simply being an alternative approach.  Episode Details: zachbitter.com/hpo-episode-367 LMNT: drinkLMNT.com/HPO deltaG: deltagketones.com - IG: @deltag.ketones HPO Sponsors: zachbitter.com/hposponsors Support HPO: zachbitter.com/hpo  Zach's Coaching: zachbitter.com/coaching Zach's Newsletter: substack.com/@zachbitter Find Andrea: unbiasedscipod.com IG: @dr.andrealove  Zach: zachbitter.com IG: @zachbitter Tw: @zbitter Substack: zachbitter.substack.com FB: @zbitterendurance Strava: Zach Bitter TikTok: @zachbitter Threads: @zachbitter

“Up until early 2020, the idea that you would wear a cloth face covering to prevent giving someone else a respiratory infection or acquiring it yourself—there was no evidence to support that. But after things had been shut down for a while, there seemed to be a need to give the public something that they could believe was going to make them safer—convince them that maybe they could go out if they just wore something over their face. That was enough. That was the appearance of safety, giving them that control—the illusion of control.”In this episode, I sit down with Dr. Steven Templeton, professor of immunology at Indiana University School of Medicine and the author of a new book, “Fear of a Microbial Planet: How a Germophobic Safety Culture Makes Us Less Safe.”“It's offering people this idea that they can completely eliminate risks—for their children, for themselves,” says Dr. Templeton.Could our fear and excessive avoidance of germs and microbes actually be backfiring? And how will the rise of what Dr. Templeton calls a “safety culture” impact future generations?