Podcasts about mammalian

Ellen lets the sand cat out of the bag. We discuss dangerously approaching Hey Arnold, refusal to poop on unfamiliar toilets, blood gushers, a myth of dirty underwear, Cat Premium, and so much more. Works Cited: “The Carnivores of West Africa” - Donovan Reginald Rosevear, 1974. Page 396 “Mammalian ear specializations in arid habitats: structural and functional evidence from sand cat (Felis margarita)” - G. T. Huang et al, Journal of Comparative Physiology A, June 2002 “Sand cat in Iran - present status, distribution and conservation challenges” - Taher Ghadirian et al., CATnews (newsletter of the IUCN's Cat Specialist Group), 2016 "Sand Cat" - International Society of Endangered Cats (ISEC) Canada “Home ranges of African sand cats (Felis margarita margarita)” - Alexander Sliwa et al., Journal of Arid Environments, March 2023 “Isabelline” - Paul Anthony Jones, HaggardHawks.com IUCN Red List: Sand Cat (Felis margarita) "DOMESTIC X SAND CAT AND PALLAS'S CAT HYBRIDS" - Sarah Hartwell, messybeast.com Links: For more information about us & our podcast, head over to our website! Follow Just the Zoo of Us on BlueSky, Facebook, Instagram & Discord! Follow Ellen on Instagram or BlueSky! Thanks to everyone who participated in this year's MaxFunDrive! Still want to get in on the action? Follow this link to support this show (and get in on our limited-time keychain sale to benefit the Center for Constitutional Rights): https://maximumfun.org/joinjustthezoo

Ellen lets the sand cat out of the bag. We discuss dangerously approaching Hey Arnold, refusal to poop on unfamiliar toilets, blood gushers, a myth of dirty underwear, Cat Premium, and so much more. Works Cited: “The Carnivores of West Africa” - Donovan Reginald Rosevear, 1974. Page 396 “Mammalian ear specializations in arid habitats: structural and functional evidence from sand cat (Felis margarita)” - G. T. Huang et al, Journal of Comparative Physiology A, June 2002 “Sand cat in Iran - present status, distribution and conservation challenges” - Taher Ghadirian et al., CATnews (newsletter of the IUCN's Cat Specialist Group), 2016 "Sand Cat" - International Society of Endangered Cats (ISEC) Canada “Home ranges of African sand cats (Felis margarita margarita)” - Alexander Sliwa et al., Journal of Arid Environments, March 2023 “Isabelline” - Paul Anthony Jones, HaggardHawks.com IUCN Red List: Sand Cat (Felis margarita) "DOMESTIC X SAND CAT AND PALLAS'S CAT HYBRIDS" - Sarah Hartwell, messybeast.com Links: For more information about us & our podcast, head over to our website! Follow Just the Zoo of Us on BlueSky, Facebook, Instagram & Discord! Follow Ellen on Instagram or BlueSky! Thanks to everyone who participated in this year's MaxFunDrive! Still want to get in on the action? Follow this link to support this show (and get in on our limited-time keychain sale to benefit the Center for Constitutional Rights): https://maximumfun.org/joinjustthezoo

Alpha-gal syndrome is an emerging and often underrecognized allergy triggered by a tick bite that can cause delayed reactions to red meat and mammalian-derived products. In this episode, host Stacy Lauderdale is joined by clinical experts Zack Stacy and Kyna Henrici to unpack the science behind alpha-gal, its implications in healthcare settings, and the operational challenges providers face in managing this complex condition.    Guest Speakers:   Zachary Stacy, Pharm.D., MS, FCCP, BCPS  Clinical Pharmacy Specialist, Surgery  BJC Health   Kyna Henrici, RN  Medical Evidence Director - Cardiovascular  Vizient, Inc.    Host:    Stacy Lauderdale, Pharm.D., BCPS  AVP, Evidence-Based Medicine  Vizient, Inc.    00:05 – Introduction  Podcast introduction and welcome to VerifiedRx  00:14 – What is alpha-gal syndrome  Overview of alpha-gal syndrome  Delayed allergic reactions after eating red meat  Often linked to tick bites  00:48 – Meet the Guests   Zack Stacy, clinical pharmacy specialist  Kyna Henrici, medical evidence director  01:10 – Understanding the Allergy  Alpha-gal is a carbohydrate in nonprimate mammals that can trigger an allergy in humans  Key difference is delayed reaction timing  Symptoms are not always easy to trace   01:32 – How It Develops  Triggered by tick bites  Immune system produces IgE antibodies   Oral exposure to alpha-gal leads to delayed reactions  IV exposure to alpha-gal can cause immediate reactions  02:17 – Prevalence and Diagnosis Challenges  More common in Midwest and southern United States  Likely underdiagnosed  Often mistaken for general food allergies  Allergy may fade over time  03:07 – Risks in Healthcare Settings  Patient safety concerns beyond food  Mammalian components in medications and devices  Examples include heparin and surgical materials  03:44 – Hidden Medication Risks  Inactive ingredients can be animal derived  Examples include glycerin, lactose, amino acids, stearates  Difficult to identify and track  04:42 – Lack of Transparency  No centralized ingredient database  Sourcing can change frequently  Variability across manufacturers and batches  05:33 – Screening in Surgical Settings  Medication review at NDC level  Identification of active and inactive ingredients  May require contacting manufacturers  06:45 – Timing Challenges  Urgent procedures limit investigation time  Manufacturer responses may take days  Alternative medications often needed  07:14 – Identifying At Risk Patients  Many patients are unaware they have alpha-gal syndrome  Screening includes questions about dairy tolerance  Three patient categories used for evaluation  08:32 – Using Dairy as a Screening Tool   Dairy tolerance helps guide risk level  Food exposure typically higher than medication exposure  Determines need for deeper review  09:12 – Managing Emergencies  Focus shifts from avoidance to risk mitigation  Use of team communication and clear documentation  Preparation for unavoidable exposure  10:03 – Prevention and Preparedness  Stock alpha-gal safe medications when possible  Prepare for allergic reactions with standard treatments  10:47 – Team Based Care Approach  Collaboration across care teams is essential  Premedication strategies may be used  Close monitoring for reactions  11:11 – Gaps in Care  Limited visibility into product ingredients  Need for better labeling and transparency  11:33 – Need for Standardization  Call for clearer guidance and clinician education  Desire for centralized resource for medication ingredients  12:24 – Monitoring Challenges  CDC tracking decreased after privatization of testing  Cases likely still increasing  12:53 – Closing Remarks    Links and Resources: Alpha-gal Syndrome | Alpha-gal Syndrome | CDC    Subscribe Today!  Apple Podcasts  Spotify  YouTube  RSS Feed   

Azim Surani, Director of Research at the Gurdon Institute and Professor Emeritus at University of Cambridge, received the Kyoto Prize in Basic Sciences, specifically in the field of Life Sciences and Medicine, for his work in demonstrating how male and female mammalian genomes receive distinct imprints during germ cell development. Genomic imprinting introduced a novel concept to Mendelian genetics and is a now fundamental principle in the life sciences. Surani's research has contributed to developmental biology and epigenetics, along with a wide range of life science fields including physiology, regenerative medicine, reproductive medicine, and plant science. Series: "Kyoto Prize Symposium" [Science] [Show ID: 41117]

Azim Surani, Director of Research at the Gurdon Institute and Professor Emeritus at University of Cambridge, received the Kyoto Prize in Basic Sciences, specifically in the field of Life Sciences and Medicine, for his work in demonstrating how male and female mammalian genomes receive distinct imprints during germ cell development. Genomic imprinting introduced a novel concept to Mendelian genetics and is a now fundamental principle in the life sciences. Surani's research has contributed to developmental biology and epigenetics, along with a wide range of life science fields including physiology, regenerative medicine, reproductive medicine, and plant science. Series: "Kyoto Prize Symposium" [Science] [Show ID: 41117]

Azim Surani, Director of Research at the Gurdon Institute and Professor Emeritus at University of Cambridge, received the Kyoto Prize in Basic Sciences, specifically in the field of Life Sciences and Medicine, for his work in demonstrating how male and female mammalian genomes receive distinct imprints during germ cell development. Genomic imprinting introduced a novel concept to Mendelian genetics and is a now fundamental principle in the life sciences. Surani's research has contributed to developmental biology and epigenetics, along with a wide range of life science fields including physiology, regenerative medicine, reproductive medicine, and plant science. Series: "Kyoto Prize Symposium" [Science] [Show ID: 41117]

Azim Surani, Director of Research at the Gurdon Institute and Professor Emeritus at University of Cambridge, received the Kyoto Prize in Basic Sciences, specifically in the field of Life Sciences and Medicine, for his work in demonstrating how male and female mammalian genomes receive distinct imprints during germ cell development. Genomic imprinting introduced a novel concept to Mendelian genetics and is a now fundamental principle in the life sciences. Surani's research has contributed to developmental biology and epigenetics, along with a wide range of life science fields including physiology, regenerative medicine, reproductive medicine, and plant science. Series: "Kyoto Prize Symposium" [Science] [Show ID: 41117]

Azim Surani, Director of Research at the Gurdon Institute and Professor Emeritus at University of Cambridge, received the Kyoto Prize in Basic Sciences, specifically in the field of Life Sciences and Medicine, for his work in demonstrating how male and female mammalian genomes receive distinct imprints during germ cell development. Genomic imprinting introduced a novel concept to Mendelian genetics and is a now fundamental principle in the life sciences. Surani's research has contributed to developmental biology and epigenetics, along with a wide range of life science fields including physiology, regenerative medicine, reproductive medicine, and plant science. Series: "Kyoto Prize Symposium" [Science] [Show ID: 41117]

1. Dan Flores introduces his book, exploring North America's mammalian evolution and human arrival. He distinguishes between indigenous species and immigrants while highlighting how early humans, as carnivorous predators, began impacting naive wildlife. (1)1860

The US vice president says there's evidence Iran ​is ‌trying to rebuild its nuclear program as the Trump Administration threatens the regime while positioning war ships in the region.If the US strikes Iran, it's vowing to hit back and fears of a regional conflict are prompting a warning from the Australian Government to citizens in Israel and Lebanon to leave while they can.The Trump Administration has put new sanctions on Iran, ahead of fresh talks in Geneva later today.The ABC's gained access to a camp in north-eastern Syria housing the wives and children of killed or captured Islamic State fighters.Two young girls have spoken about their desire to go home and buy things like toys and ice cream, as debate rages in Australia about whether to assist them, given the poor conditions in the camp.The Federal Government's insisting it won't do anything to help them come home, even though it can't stop most of them entering the country, if they do make it to Australian shores.A teenager from the New South Wales' Central Coast has become the first Australian confirmed to have died from a tick-induced red meat allergy.Jeremy Webb began having difficulty breathing after eating beef sausages on a camping trip and he later died in hospital.The state's coroner has ruled he died from an anaphylactic reaction to mammalian meat allergy, which triggered an asthma attack.There's only been one other fatal case known of in the world.

This episode explores Alpha-gal syndrome, a tick-associated allergy that causes delayed reactions to mammalian products and is often missed in clinical settings. The conversation with Jeffery Strickler, DHA, RN highlights how Alpha-gal differs from other tick-borne illnesses, the wide range of symptoms nurses may see, and why delayed nighttime reactions are a major clue. The episode also covers hidden risks in medications and medical products and emphasizes the critical role nurses play in recognition, patient education, and safety.   Explore related articles for more information: "Tick-borne diseases in the US" in the July 2024 issue of Nursing and "Mammalian meat allergy: Unexpected danger" in the August 2017 issue of Nursing.   Transcript

The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.

Q&A episode with Annette's top takeaways from Russell Beck + critical advice for dealing with burnout at work.IN THIS EPISODE:Annette's 3 Takeaways from Russell Beck:1. The Rise of Artist Engineers (STEM → STEAM)Why creativity and art matter more than ever in the future of work. Drawing as a tool for thinking.2. One Size Fits OneManagers need to understand how each person works best while balancing the team's needs.3. Work as a Friend FactoryWhy having friends at work isn't just nice—it's critical for engagement, retention, and culture.Listener Question: Burnout at a Major OrganisationEllie asked: How do I get out of a toxic workplace without destroying my career?Cathal's advice:- You need at least 2 months off to recover- Consider consulting/contract work instead of another corporate role- Get back to the work you love (not just management drama)Annette's practical daily tactics:- 10-minute morning meditation (Calm app)- Mammalian dive reflex for grounding (2-min exercise)- Schedule 20-min coffee with work friends- Weekend self-care: massage, sauna, nature walks- Career counseling or coaching- Bill Cowan's career transition processKey Insights:"Work can be a friend factory." - Aisha Bousaid"Employees with a best friend at work are 7x more likely to be fully engaged." - Gallup"We take jobs for the salary. We quit because of culture." - Bruce Daisley"Burnout is really real. The longer it goes on, the harder it is to pull back out." - Annette SloanResources:Books: "Drawing on the Right Side of the Brain" by Betty Edwards, "Building a Winning Career" by Bill CowanApps: Calm (meditation)Better at Work: Better Careers modules at betteratwork.netSubmit your career dilemma: betteratwork.netNext Episode: Laura Gassner-Otting on "Limitless: How to Ignore Everybody and Carve Your Own Path"Better at Work - Making work better, one conversation at a time.New episodes every Thursday.Hosted by Cathal Quinlan & Annette Sloan

How does a tick bite end up with you being allergic to meat? It might sound the stuff of science fiction, but there's a syndrome called 'alpha-gal syndrome' which can be traced back to being bitten by a certain type of tick. The allergy is more commonly called the 'Mammalian meat allergy', with those affected potentially ending up being allergic to meat.

Matters Microbial #117: Cancer Virus Hunters and Molecular Biology December 8, 2025 Today Dr. Gregory Morgan, Professor in the School of Humanities, Arts, and Social Sciences at Stevens Institute of Technology, joins the #QualityQuorum to discuss how cancer causing viruses advanced molecular biology as described in his recent book Cancer Virus Hunters.   Host: Mark O. Martin Guest: Gregory Morgan Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a link to Dr. Morgan's book on the topic discussed today. A lovely interview with Dr. Morgan about his book. A great history of molecular biology, "Eighth Day of Creation" by Horace Freeland Judson. The History and Philosophy of Science program at the University of Pittsburgh.   An overview of the Rous Sarcoma Virus. A biography of Dr. Peyton Rous. A video describing how RSV causes cancer by "stealing" normal genes. How some viruses may contribute to the development of cancer. Here is another video on that topic. The field of tumor virology.  A really wonderful video on the genetic origin for cancer. An overview of oncogenes and protooncogenes. A video exploring how proto-oncogenes become oncogenes, and can contribute to the development of cancer. The concept of "contagious cancer" that is rare but exists. The story of papilloma viruses and "jackalopes." The history of Cold Spring Harbor Laboratory. An overview of retroviruses. Retroviruses and FeLV.  Blue chicken eggs and ancient retroviruses. A summary for novice #Micronauts. Mammalian (including human) placenta and ancient retroviruses. Nixon's "War on Cancer." An overview of the src gene. An overview of the ras gene. An overview of the p53 gene. A video explainer of the enzyme reverse transcriptase. A biography of Howard Temin. A biography of David Baltimore. The story of Human Papillovirus (HPV) and cancer. Dr. Morgan's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

ColloqueJournée François JacobThe Living Clock: Biology in the Flow of TimeCollège de FranceAnnée 2025-2026Mechanics of Mammalian DevelopmentJean-Léon MaitreInstitut Curie, Paris France

Peach fuzz. Chin hairs. Mammalian ponytails. WHY DO THEY HAPPEN. Yale researcher and associate professor Dr. Valerie Horsley stops by California to chat with Alie about the nature of hair and what it has to do with skin and nails, stem cells, how it grows, why some of us have curly hair or straight hair or thin hair or thick hair, and why we love and hate and need our hair as animals.Dr. Valerie Horsely is on Facebook and BlueskyThe Horsely Lab at YaleFull-length (*not* G-rated) Trichology episode + tons of science linksMore kid-friendly Smologies episodes!Become a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, hoodies, totes!Follow Ologies on Instagram and BlueskyFollow Alie Ward on Instagram and TikTokSound editing by Mercedes Maitland of Maitland Audio Productions and Steven Ray MorrisMade possible by work from Noel Dilworth, Susan Hale, Jake Chaffee, Kelly R. Dwyer, Aveline Malek and Erin TalbertSmologies theme song by Harold Malcolm Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this episode of the Epigenetics Podcast, we talked with Emily Wong from the University of New South Wales in Sydney about her work on how evolution shapes mammalian genes. As the head of the Regulatory Systems Lab at the Victor Chang Cardiac Research Institute and an associate professor at UNSW, Emily's research centers on gene control and enhancers. We delve into her pivotal 2017 publication in Nature Communications, where she investigated transcription factor binding in liver-specific contexts, shedding light on the regulatory mechanisms at play in mammals. Emily elaborates on her postdoctoral work at the European Bioinformatics Institute and the innovative hybrid systems she used to dissect genetic variation effects, which allowed her to differentiate between cis-regulatory and trans-regulatory influences. By employing techniques like ChIP-seq, she was able to illustrate the combinatorial effects of transcription factors on gene expression, paving the way for her collaborative efforts across disciplines and organisms. We also examine Emily's findings regarding enhancer function through comparative studies between zebrafish and marine sponges. Using historical data on conserved genetic sequences, she and her team identified enhancer regions that displayed activity in specific vertebrate cell types, despite their evolutionary divergence from sponges. This unexpected result suggests deeper insights into how enhancers can be co-opted for new functions as species evolve. Furthermore, we dive into Emily's latest ventures involving advanced methodologies such as chromatin accessibility profiling with ATAC-seq and how these insights can elucidate the genomic landscape of metazoan embryogenesis. She highlights significant correlations between enhancer turnover and DNA replication timing, suggesting evolutionary implications that should be taken into account in future genomic studies.   References Wong, E. S., Zheng, D., Tan, S. Z., Bower, N. I., Garside, V., Vanwalleghem, G., Gaiti, F., Scott, E., Hogan, B. M., Kikuchi, K., McGlinn, E., Francois, M., & Degnan, B. M. (2020). Deep conservation of the enhancer regulatory code in animals. Science, 370(6517), eaax8137. https://doi.org/10.1126/science.aax8137 Cornejo-Páramo, P., Petrova, V., Zhang, X. et al. Emergence of enhancers at late DNA replicating regions. Nat Commun 15, 3451 (2024). https://doi.org/10.1038/s41467-024-47391-5   Related Episodes Ultraconserved Enhancers and Enhancer Redundancy (Diane Dickel) Enhancer Communities in Adipocyte Differentiation (Susanne Mandrup) Enhancer-Promoter Interactions During Development (Yad Ghavi-Helm)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Interview with Ehsan Rahimy, MD, author of Mammalian Target Rapamycin Inhibition as a Therapeutic Target for Prevention of Proliferative Vitreoretinopathy. Hosted by Neil Bressler, MD. Related Content: Mammalian Target Rapamycin Inhibition as a Therapeutic Target for Prevention of Proliferative Vitreoretinopathy

Interview with Ehsan Rahimy, MD, author of Mammalian Target Rapamycin Inhibition as a Therapeutic Target for Prevention of Proliferative Vitreoretinopathy. Hosted by Neil Bressler, MD. Related Content: Mammalian Target Rapamycin Inhibition as a Therapeutic Target for Prevention of Proliferative Vitreoretinopathy

Scientific advancements are highlighted with AI designing synthetic DNA for gene control and Anthropic launching a programme to support scientific research with AI. Societal and ethical concerns feature prominently, including Reddit strengthening verification against human-like bots, Pope Leo XIV identifying AI as a key challenge, and artists calling for stronger copyright protection against AI use of their work. The sources also mention practical applications like California's multilingual wildfire chatbot and technical issues such as the persistence of AI hallucinations. Finally, industry and regulatory dynamics are covered with Anthropic warning the DOJ about potential negative impacts of a Google antitrust proposal and SoundCloud facing backlash over terms regarding AI training data.

On today's episode, Scientists at CERN have successfully turned lead into gold -- a process that requires a shocking amount of speed! Another company touts its T-Rex leather handbags. How do scientists feel about said claim? Plus, researchers link the immune system to mammalian lifespan, and on This Day in History; the first paper currency in the US. These companies want to make hand bags out of T-rex leather. But scientists aren't buying it Mammal's lifespans linked to brain size and immune system function, says new study CERN Creates Gold from Lead and There's No Magic, Just Physics The History of US Currency Continentals: What it Means, History, Worth The Paper Revolution United States Continental Paper Currency VIDEO: US National Archives: The Continental Dollar: How the American Revolution Was Financed with Paper Money Learn more about your ad choices. Visit megaphone.fm/adchoices

歡迎嚟到 搞乜咁科學 GMG Science 第33集！今集嘅主題係《一個人生B與叻過ChatGPT Baby Making DIY & Human Outsmarting AI》

On today's episode; the oldest mammalian ancestor is discovered, an update on the flight of the Parker Solar Probe, plus, on 'This Day in History', the show that would influence children's television for generations to come -- Howdy Doody. World's oldest mammalian ancestor discovered in Mallorca This dog-like predator is the oldest known mammal ancestor | Popular Science Early–middle Permian Mediterranean gorgonopsian suggests an equatorial origin of therapsids | Nature Communications TDIH: Norb's Corner: “It's Howdy Doody time!” TDIH: 1947: NBC Introduces Howdy Doody on 'Puppet Playhouse Presents' From Doodyville to Detroit: The History of Howdy Doody, a Legendary Show of the Golden Age of TV Contact the show - coolstuffcommute@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

* List of Discoveries Squeezing Evolution: Did you know that dinosaurs ate rice before rice evolved? That turtle shells existed forty million years before turtle shells began evolving? That insects evolved tongues for eating from flowers 70 million years before flowers evolved? And that birds appeared before birds evolved? The fossil record is a wonderful thing. And more recently, only a 40,000-year squeeze, Neanderthal had blood types A, B, and O, shocking evolutionists but expected to us here at Real Science Radio! Sit back and get ready to enjoy another instant classic, today's RSR "list show" on Evolution's Big Squeeze! Our other popular list shows include: - scientists doubting Darwin - evidence against whale evolution - problems with 'the river carved the canyon' - carbon 14 everywhere it shouldn't be - dinosaur still-soft biological tissue - solar system formation problems - evidence against the big bang - evidence for the global flood - genomes that just don't fit - and our list of not so old things! (See also rsr.org/sq2 and rsr.org/sq3!) * Evolution's Big Squeeze: Many discoveries squeeze the Darwinian theory's timeframe and of course without a workable timeframe there is no workable theory. Examples, with their alleged (and falsified) old-earth timeframes, include: - Complex skeletons existed 9 million years before they were thought to have evolved, before even the "Cambrian explosion".- Butterflies existed 10 million years before they were thought to have evolved. - Parrots existed "much earlier than had been thought", in fact, 25 million years before they were thought to have evolved. - Cephalopod fossils (squids, cuttlefish, etc.) appear 35 million years before they were able to propagate. - Turtle shells 40 million years before turtle shells began evolving - Trees began evolving 45 million years before they were thought to evolve - Spores appearing 50 million years before the plants that made them (not unlike footprints systematically appearing "millions of years before" the creatures that made them, as affirmed by Dr. Marcus Ross, associate professor of geology). - Sponges existed 60 million years before they were believed to have evolved. - Dinosaurs ate rice before it evolved Example - Insect proboscis (tongue) in moths and butterflies 70 million years before previously believed has them evolving before flowers. - Arthropod brains fully developed with central nervous system running to eyes and appendages just like modern arthropods 90 million years earlier than previously known (prior to 2021, now, allegedly 310mya) - 100 million years ago and already a bird - Fossil pollen pushes back plant evolution 100 million years. - Mammalian hair allegedly 100-million-years-old show that, "the morphology of hair cuticula may have remained unchanged throughout most of mammalian evolution", regarding the overlapping cells that lock the hair shaft into its follicle. - Piranha-like flesh-eating teeth (and bitten prey) found pushing back such fish 125 million years earlier than previously claimed   - Shocking organic molecules in "200 million-years-old leaves" from ginkgoes and conifers show unexpected stasis. - Plant genetic sophistication pushed back 200 million years. - Jellyfish fossils (Medusoid Problematica :) 200 million years earlier than expected; here from 500My ago. - Green seaweed 200 million years earlier than expected, pushed back now to a billion years ago!  - The acanthodii fish had color vision 300 million years ago, but then, and wait, Cheiracanthus fish allegedly 388 million years ago already had color vision. - Color vision (for which there is no Darwinian evolutionary small-step to be had, from monochromatic), existed "300 million years ago" in fish, and these allegedly "120-million-year-old" bird's rod and cone fossils stun researchers :) - 400-million-year-old Murrindalaspis placoderm fish "eye muscle attachment, the eyestalk attachment and openings for the optic nerve, and arteries and veins supplying the eyeball" The paper's author writes, "Of course, we would not expect the preservation of ancient structures made entirely of soft tissues (e.g. rods and cone cells in the retina...)." So, check this next item... :) - And... no vertebrates in the Cambrian? Well, from the journal Nature in 2014, a "Lower-Middle Cambrian... primitive fish displays unambiguous vertebrate features: a notochord, a pair of prominent camera-type eyes, paired nasal sacs, possible cranium and arcualia, W-shaped myomeres, and a post-anal tail" Primitive? - Fast-growing juvenile bone tissue, thought to appear in the Cretaceous, has been pushed back 100 million years: "This pushes the origin of fibrolamellar bone in Sauropterygia back from the Cretaceous to the early Middle Triassic..."- Trilobites "advanced" (not the predicted primitive) digestion "525 million" years ago - And there's this, a "530 million year old" fish, "50 million years before the current estimate of when fish evolved" - Mycobacterium tuberculosis 100,000 yr-old MRCA (most recent common ancestor) now 245 million- Fungus long claimed to originate 500M years ago, now found at allegedly 950 Mya (and still biological "the distant past... may have been much more 'modern' than we thought." :) - A rock contained pollen a billion years before plants evolved, according to a 2007 paper describing "remarkably preserved" fossil spores in the French Alps that had undergone high-grade metamorphism - 2.5 billion year old cyanobacteria fossils (made of organic material found in a stromatolite) appear about "200 million years before the [supposed] Great Oxidation Event". - 2.7 billion year old eukaryotes (cells with a nucleus) existed (allegedly) 1 billion years before expected - 3.5 billion year "cell division evidently identical to that of living filamentous prokaryotes." - And even older cyanobacteria! At 220 million years earlier than thought, per Nature's 3.7 billion year old dating of stromatolites! - The universe and life itself (in 2019 with the universe dated a billion, now, no, wait, two billion!, years younger than previously thought, that's not only squeezing biological but also astronomical evolution, with the overall story getting really tight) - Mantis shrimp, with its rudimentary color but advanced UV vision, is allegedly ancient. - Hadrosaur teeth, all 1400 of them, were "more complex than those of cows, horses, and other well-known modern grazers." Professor stunned by the find! (RSR predicts that, by 2030 just to put an end date on it, more fossils will be found from the geologic column that will be more "advanced" as compared to living organisms, just like this hadrosaur and like the allegedly 100M year old hagfish  fossil having more slime glands than living specimens.)  - Trace fossils "exquisitely preserved" of mobile organisms (motility) dated at 2.1 billion years ago, a full 1.5 billion earlier than previously believed - Various multicellular organisms allegedly 2.1 billion years old, show multicellularity 1.5 billion years sooner than long believed   - Pre-sauropod 26,000-pound dinosaur "shows us that even as far back as 200 million years ago, these animals had already become the largest vertebrates to ever walk the Earth." - The Evo-devo squeeze, i.e., evolutionary developmental biology, as with rsr.org/evo-devo-undermining-darwinism. - Extinct Siberian one-horned rhinos coexisted with mankind. - Whale "evolution" is being crushed in the industry-wide "big squeeze". First, geneticist claims whales evolved from hippos but paleontologists say hippos evolved tens of millions of years too late! And what's worse than that is that fossil finds continue to compress the time available for whale evolution. To not violate its own plot, the Darwinist story doesn't start animals evolving back into the sea until the cast includes land animals suitable to undertake the legendary journey. The recent excavation of whale fossils on an island of the Antarctic Peninsula further compresses the already absurdly fast 10 million years to allegedly evolve from the land back to the sea, down to as little as one million years. BioOne in 2016 reported a fossil that is "among the oldest occurrences of basilosaurids worldwide, indicating a rapid radiation and dispersal of this group since at least the early middle Eocene." By this assessment, various techniques produced various published dates. (See the evidence that falsifies the canonical whale evolution story at rsr.org/whales.) * Ancient Hierarchical Insect Society: "Thanks to some well-preserved remains, researchers now believe arthropod social structures have been around longer than anyone ever imagined. The encased specimens of ants and termites recently studied date back [allegedly] 100 million years." Also from the video about "the bubonic plague", the "disease is well known as a Middle Ages mass killer... Traces of very similar bacteria were found on [an allegedly] 20-million-year-old flea trapped in amber." And regarding "Caribbean lizards... Even though they are [allegedly] 20 million years old, the reptiles inside the golden stones were not found to differ from their contemporary counterparts in any significant way. Scientists attribute the rarity [Ha! A rarity or the rule? Check out rsr.org/stasis.] to stable ecological surroundings." * Squeezing and Rewriting Human History: Some squeezing simply makes aspects of the Darwinian story harder to maintain while other squeezing contradicts fundamental claims. So consider the following discoveries, most of which came from about a 12-month period beginning in 2017 which squeeze (and some even falsify) the Out-of-Africa model: - find two teeth and rewrite human history with allegedly 9.7 million-year-old teeth found in northern Europe (and they're like Lucy, but "three times older") - date blue eyes, when humans first sported them, to as recently as 6,000 years ago   - get mummy DNA and rewrite human history with a thousand years of ancient Egyptian mummy DNA contradicting Out-of-Africa and demonstrating Out-of-Babel - find a few footprints and rewrite human history with allegedly 5.7 million-year-old human footprints in Crete - re-date an old skull and rewrite human history with a very human skull dated at 325,000 years old and redated in the Journal of Physical Anthropology at about 260,000 years old and described in the UK's Independent, "A skull found in China [40 years ago] could re-write our entire understanding of human evolution." - date the oldest language in India, Dravidian, with 80 derivatives spoken by 214 million people, which appeared on the subcontinent only about 4,500 years ago, which means that there is no evidence for human language for nearly 99% of the time that humans were living in Asia. (Ha! See rsr.org/origin-of-language for the correct explanation.) - sequence a baby's genome and rewrite human history with a 6-week old girl buried in Alaska allegedly 11,500 years ago challenging the established history of the New World. (The family buried this baby girl just beneath their home like the practice in ancient Mesopotamia, the Hebrews who sojourned in Egypt, and in Çatalhöyük in southern Turkey, one of the world's most ancient settlements.) - or was that 130,000? years ago as the journal Nature rewrites human history with a wild date for New World site - and find a jawbone and rewrite human history with a modern looking yet allegedly 180,000-year-old jawbone from Israel which "may rewrite the early migration story of our species" by about 100,000 years, per the journal Science - re-date a primate and lose yet another "missing link" between "Lucy" and humans, as Homo naledi sheds a couple million years off its age and drops from supposedly two million years old to (still allegedly) about 250,000 years old, far too "young" to be the allegedly missing link - re-analysis of the "best candidate" for the most recent ancestor to human beings, Australopithecus sediba, turns out to be a juvenile Lucy-like ape, as Science magazine reports work presented at the American Association of Physical Anthropologists 2017 annual meeting - find skulls in Morocco and "rewrite human history" admits the journal Nature, falsifying also the "East Africa" part of the canonical story - and from the You Can't Make This Stuff Up file, NPR reports in April 2019, Ancient Bones And Teeth Found In A Philippine Cave May Rewrite Human History. :) - Meanwhile, whereas every new discovery requires the materialists to rewrite human history, no one has had to rewrite Genesis, not even once. Yet, "We're not claiming that the Bible is a science textbook. Not at all. For the textbooks have to be rewritten all the time!"  - And even this from Science: "humans mastered the art of training and controlling dogs thousands of years earlier than previously thought."- RSR's Enyart commented on the Smithsonian's 2019 article on ancient DNA possibly deconstructing old myths...  This Smithsonian article about an ancient DNA paper in Science Advances, or actually, about the misuse of such papers, was itself a misuse. The published research, Ancient DNA sheds light on the genetic origins of early Iron Age Philistines, confirmed Amos 9:7 by documenting the European origin of the biblical Philistines who came from the island of Caphtor/Crete. The mainstream media completely obscured this astounding aspect of the study but the Smithsonian actually stood the paper on its head. [See also rsr.org/archaeology.]* Also Squeezing Darwin's Theory: - Evolution happens so slowly that we can't see it, yet - it happens so fast that millions of mutations get fixed in a blink of geologic time AND: - Observing a million species annually should show us a million years of evolution, but it doesn't, yet - evolution happens so fast that the billions of "intermediary" fossils are missing AND: - Waiting for helpful random mutations to show up explains the slowness of evolution, yet - adaption to changing environments is often immediate, as with Darwin's finches Finches Adapt in 17 Years, Not 2.3 Million: Charles Darwin's finches are claimed to have taken 2,300,000 years to diversify from an initial species blown onto the Galapagos Islands. Yet individuals from a single finch species on a U.S. Bird Reservation in the Pacific were introduced to a group of small islands 300 miles away and in at most 17 years, like Darwin's finches, they had diversified their beaks, related muscles, and behavior to fill various ecological niches. So Darwin's finches could diversify in just 17 years, and after 2.3 million more years, what had they evolved into? Finches! Hear this also at rsr.org/lee-spetner and see Jean Lightner's review of the Grants' 40 Years. AND: - Fossils of modern organisms are found "earlier" and "earlier" in the geologic column, and - the "oldest" organisms are increasingly found to have anatomical, proteinaceous, prokaryotic, and eukaryotic sophistication and similarity to "modern" organisms AND: - Small populations are in danger of extinction (yet they're needed to fix mutations), whereas - large populations make it impossible for a mutation to become standard AND: - Mutations that express changes too late in an organism's development can't effect its fundamental body plan, and - mutations expressed too early in an organism's development are fatal (hence among the Enyart sayings, "Like evolving a vital organ, most major hurdles for evolutionary theory are extinction-level events.") AND: - To evolve flight, you'd get bad legs - long before you'd get good wings AND: - Most major evolutionary hurdles appear to be extinction-level events- yet somehow even *vital* organs evolve (for many species, that includes reproductive organs, skin, brain, heart, circulatory system, kidney, liver, pancreas, stomach, small intestines, large intestines, lungs -- which are only a part of the complex respiration system) AND: - Natural selection of randomly taller, swifter, etc., fish, mammals, etc. explains evolution yet - development of microscopic molecular machines, feedback mechanisms, etc., which power biology would be oblivous to what's happening in Darwin's macro environment of the entire organism AND: - Neo-Darwinism suggests genetic mutation as the engine of evolution yet - the there is not even a hypothesis for modifying the vast non-genetic information in every living cell including the sugar code, electrical code, the spatial (geometric) code, and the epigenetic code AND: - Constant appeals to "convergent" evolution (repeatedly arising vision, echolocation, warm-bloodedness, etc.) - undermine most Darwinian anatomical classification especially those based on trivialities like odd or even-toed ungulates, etc. AND: - Claims that given a single species arising by abiogenesis, then - Darwinism can explain the diversification of life, ignores the science of ecology and the (often redundant) biological services that species rely upon AND: - humans' vastly superior intelligence indicates, as bragged about for decades by Darwinists, that ape hominids should have the greatest animal intelligence, except that - many so-called "primitive" creatures and those far distant on Darwin's tee of life, exhibit extraordinary rsr.org/animal-intelligence even to processing stimuli that some groups of apes cannot AND: - Claims that the tree of life emerges from a single (or a few) common ancestors - conflict with the discoveries of multiple genetic codes and of thousands of orphan genes that have no similarity (homology) to any other known genes AND (as in the New Scientist cover story, "Darwin Was Wrong about the tree of life", etc.): - DNA sequences have contradicted anatomy-based ancestry claims - Fossil-based ancestry claims have been contradicted by RNA claims - DNA-based ancestry claims have been contradicted by anatomy claims - Protein-based ancestry claims have been contradicted by fossil claims. - And the reverse problem compared to a squeeze. Like finding the largest mall in America built to house just a kid's lemonade stand, see rsr.org/200 for the astounding lack of genetic diversity in humans, plants, and animals, so much so that it could all be accounted for in just about 200 generations! - The multiplied things that evolved multiple times - Etc. * List of Ways Darwinists Invent their Tree of Life, aka Pop Goes the Weasle – Head and Shoulders, Knees and Toes: Evolutionists change their selection of what evidence they use to show 'lineage', from DNA to fossils to genes to body plans to teeth to many specific anatomical features to proteins to behavior to developmental similarities to habitat to RNA, etc. and to a combination of such. Darwinism is an entire endeavor based on selection bias, a kind of logical fallacy. By anti-science they arbitrarily select evidence that best matches whichever evolutionary story is currently preferred." -Bob E. The methodology used to create the family tree edifice to show evolutionary relationships classifies the descent of organisms based on such attributes as odd-toed and even-toed ungulates. Really? If something as wildly sophisticated as vision allegedly evolved multiple times (a dozen or more), then for cryin' out loud, why couldn't something as relatively simple as odd or even toes repeatedly evolve? How about dinosaur's evolving eggs with hard shells? Turns out that "hard-shelled eggs evolved at least three times independently in dinosaurs" (Nature, 2020). However, whether a genus has an odd or even number of toes, and similar distinctions, form the basis for the 150-year-old Darwinist methodology. Yet its leading proponents still haven't acknowledged that their tree building is arbitrary and invalid. Darwin's tree recently fell anyway, and regardless, it has been known to be even theoretically invalid all these many decades. Consider also bipedalism? In their false paradigm, couldn't that evolve twice? How about vertebrate and non-vertebrates, for that matter, evolving multiple times? Etc., etc., etc. Darwinists determine evolutionary family-tree taxonomic relationships based on numbers of toes, when desired, or on hips (distinguishing, for example, dinosaur orders, until they didn't) or limb bones, or feathers, or genes, or fossil sequence, or neck bone, or..., or..., or... Etc. So the platypus, for example, can be described as evolving from pretty much whatever story would be in vogue at the moment...   * "Ancient" Protein as Advanced as Modern Protein: A book review in the journal Science states, "the major conclusion is reached that 'analyses made of the oldest fossils thus far studied do not suggest that their [allegedly 145-million year-old] proteins were chemically any simpler than those now being produced.'" 1972, Biochemistry of Animal Fossils, p. 125 * "Ancient" Lampreys Just Modern Lampreys with Decomposed Brain and Mouth Parts: Ha! Researches spent half-a-year documenting how fish decay. RSR is so glad they did! One of the lessons learned? "[C]ertain parts of the brain and the mouth that distinguish the animals from earlier relatives begin a rapid decay within 24 hours..." :) * 140-million Year Old Spider Web: The BBC and National Geographic report on a 140-million year old spider web in amber which, as young-earth creationists expect, shows threads that resemble silk spun by modern spiders. Evolutionary scientists on the otherhand express surprise "that spider webs have stayed the same for 140 million years." And see the BBC. * Highly-Credentialed Though Non-Paleontologist on Flowers: Dr. Harry Levin who spent the last 15 years of a brilliant career researching paleontology presents much evidence that flowering plants had to originate not 150 million years ago but more than 300 million years ago. (To convert that to an actual historical timeframe, the evidence indicates flowers must have existed prior to the time that the strata, which is popularly dated to 300 mya, actually formed.) * Rampant Convergence: Ubiquitous appeals to "convergent" evolution (vision, echolocation, warm-bloodedness, icthyosaur/dolphin anatomy, etc.), all allegedly evolving multiple times, undermines anatomical classification based on trivialities like odd or even-toed ungulates, etc. * Astronomy's Big Evolution Squeeze: - Universe a billion, wait, two billion, years younger than thought   (so now it has to evolve even more impossibly rapidly) - Sun's evolution squeezes biological evolution - Galaxies evolving too quickly - Dust evolving too quickly - Black holes evolving too quickly - Clusters of galaxies evolving too quickly. * The Sun's Evolution Squeezes Life's Evolution: The earlier evolutionists claim that life began on Earth, the more trouble they have with astrophysicists. Why? They claim that a few billion years ago the Sun would have been far more unstable and cooler. The journal Nature reports that the Faint young Sun paradox remains for the "Sun was fainter when the Earth was young, but the climate was generally at least as warm as today". Further, our star would shoot out radioactive waves many of which being violent enough to blow out Earth's atmosphere into space, leaving Earth dead and dry like Mars without an atmosphere. And ignoring the fact that powerful computer simulators cannot validate the nebula theory of star formation, if the Sun had formed from a condensing gas cloud, a billion years later it still would have been emitting far less energy, even 30% less, than it does today. Forget about the claimed one-degree increase in the planet's temperature from man-made global warming, back when Darwinists imagine life arose, by this just-so story of life spontaneously generating in a warm pond somewhere (which itself is impossible), the Earth would have been an ice ball, with an average temperature of four degrees Fahrenheit below freezing! See also CMI's video download The Young Sun. * Zircons Freeze in Molten Eon Squeezing Earth's Evolution? Zircons "dated" 4 to 4.4 billion years old would have had to freeze (form) when the Earth allegedly was in its Hadean (Hades) Eon and still molten. Geophysicist Frank Stacey (Cambridge fellow, etc.) has suggested they may have formed above ocean trenches where it would be coolest. One problem is that even further squeezes the theory of plate tectonics requiring it to operate two billion years before otherwise claimed. A second problem (for these zircons and the plate tectonics theory itself) is that ancient trenches (now filled with sediments; others raised up above sea level; etc.) have never been found. A third problem is that these zircons contain low isotope ratios of carbon-13 to carbon-12 which evolutionists may try to explain as evidence for life existing even a half-billion years before they otherwise claim. For more about this (and to understand how these zircons actually did form) just click and then search (ctrl-f) for: zircon character. * Evolution Squeezes Life to Evolve with Super Radioactivity: Radioactivity today breaks chromosomes and produces neutral, harmful, and fatal birth defects. Dr. Walt Brown reports that, "A 160-pound person experiences 2,500 carbon-14 disintegrations each second", with about 10 disintergrations per second in our DNA. Worse for evolutionists is that, "Potassium-40 is the most abundant radioactive substance in... every living thing." Yet the percentage of Potassium that was radioactive in the past would have been far in excess of its percent today. (All this is somewhat akin to screws in complex machines changing into nails.) So life would have had to arise from inanimate matter (an impossibility of course) when it would have been far more radioactive than today. * Evolution of Uranium Squeezed by Contrasting Constraints: Uranium's two most abundant isotopes have a highly predictable ratio with 235U/238U equaling 0.007257 with a standard deviation of only 0.000017. Big bang advocates claim that these isotopes formed in distant stellar cataclysms. Yet that these isotopes somehow collected in innumerable small ore bodies in a fixed ratio is absurd. The impossibility of the "big bang" explanation of the uniformity of the uranium ratio (rsr.org/bb#ratio) simultaneously contrasts in the most shocking way with its opposite impossibility of the missing uniform distribution of radioactivity (see rsr.org/bb#distribution) with 90% of Earth's radioactivity in the Earth's crust, actually, the continental crust, and even at that, preferentially near granite! A stellar-cataclysmic explanation within the big bang paradigm for the origin of uranium is severely squeezed into being falsified by these contrasting constraints. * Remarkable Sponges? Yes, But For What Reason? Study co-author Dr. Kenneth S. Kosik, the Harriman Professor of Neuroscience at UC Santa Barbara said, "Remarkably, the sponge genome now reveals that, along the way toward the emergence of animals, genes for an entire network of many specialized cells evolved and laid the basis for the core gene logic of organisms that no longer functioned as single cells." And then there's this: these simplest of creatures have manufacturing capabilities that far exceed our own, as Degnan says, "Sponges produce an amazing array of chemicals of direct interest to the pharmaceutical industry. They also biofabricate silica fibers directly from seawater in an environmentally benign manner, which is of great interest in communications [i.e., fiber optics]. With the genome in hand, we can decipher the methods used by these simple animals to produce materials that far exceed our current engineering and chemistry capabilities." Kangaroo Flashback: From our RSR Darwin's Other Shoe program: The director of Australia's Kangaroo Genomics Centre, Jenny Graves, that "There [are] great chunks of the human genome… sitting right there in the kangaroo genome." And the 20,000 genes in the kangaroo (roughly the same number as in humans) are "largely the same" as in people, and Graves adds, "a lot of them are in the same order!" CMI's Creation editors add that "unlike chimps, kangaroos are not supposed to be our 'close relatives.'" And "Organisms as diverse as leeches and lawyers are 'built' using the same developmental genes." So Darwinists were wrong to use that kind of genetic similarity as evidence of a developmental pathway from apes to humans. Hibernating Turtles: Question to the evolutionist: What happened to the first turtles that fell asleep hibernating underwater? SHOW UPDATE Of Mice and Men: Whereas evolutionists used a very superficial claim of chimpanzee and human genetic similarity as evidence of a close relationship, mice and men are pretty close also. From the Human Genome Project, How closely related are mice and humans?, "Mice and humans (indeed, most or all mammals including dogs, cats, rabbits, monkeys, and apes) have roughly the same number of nucleotides in their genomes -- about 3 billion base pairs. This comparable DNA content implies that all mammals [RSR: like roundworms :)] contain more or less the same number of genes, and indeed our work and the work of many others have provided evidence to confirm that notion. I know of only a few cases in which no mouse counterpart can be found for a particular human gene, and for the most part we see essentially a one-to-one correspondence between genes in the two species." * Related RSR Reports: See our reports on the fascinating DNA sequencing results from roundworms and the chimpanzee's Y chromosome! * Genetic Bottleneck, etc: Here's an excerpt from rsr.org/why-was-canaan-cursed... A prediction about the worldwide distribution of human genetic sequencing (see below) is an outgrowth of the Bible study at that same link (aka rsr.org/canaan), in that scientists will discover a genetic pattern resulting from not three but four sons of Noah's wife. Relevant information comes also from mitochondrial DNA (mtDNA) which is not part of any of our 46 chromosomes but resides outside of the nucleus. Consider first some genetic information about Jews and Arabs, Jewish priests, Eve, and Noah. Jews and Arabs Biblical Ancestry: Dr. Jonathan Sarfati quotes the director of the Human Genetics Program at New York University School of Medicine, Dr. Harry Ostrer, who in 2000 said: Jews and Arabs are all really children of Abraham … And all have preserved their Middle Eastern genetic roots over 4,000 years. This familiar pattern, of the latest science corroborating biblical history, continues in Dr. Sarfati's article, Genesis correctly predicts Y-Chromosome pattern: Jews and Arabs shown to be descendants of one man. Jewish Priests Share Genetic Marker: The journal Nature in its scientific correspondence published, Y Chromosomes of Jewish Priests, by scie

Amelia Macho chats to Functional Ecology author Patrick Finnerty about his recently published research article "Odour information enables patch choice by mammalian herbivores from afar, leading to predictable plant associational effects". The team demonstrated that elephants can make patch choice decisions from afar using plant odour cues alone, and that these decisions lead to predictable associational effects on the susceptibility of high-quality focal plants to be being eaten. They also used a new method to reduce an entire complex odour profile of a low-quality plant species and reproduce this odour information artificially. This simplified odour set was as effective as real low-quality neighbours in shaping elephant patch choice and subsequently providing associational refuge to the focal plant. This research could offer a new tool to influence herbivore foraging decisions, with implications for wildlife management and conservation, including plant protection. Read the full research article here: https://doi.org/10.1111/1365-2435.14665 Check out our YouTube channel for a video of an elephant walking through the giant Y-maze Patt and his team built: https://youtu.be/OBY_xsbU-0k

In this installment of the Longevity & Aging Series, Dr. Jon Berner from the Woodinville Psychiatric Associates in Woodinville, WA, joined host Dr. Evgeniy Galimov to discuss a research paper he co-authored that was published in Volume 16, Issue 14 of Aging (Aging-US), entitled, “mTORC1 activation in presumed classical monocytes: observed correlation with human size variation and neuropsychiatric disease.” DOI - https://doi.org/10.18632/aging.206033 Corresponding author - Jon Berner - jonbernermd@gmail.com Video interview - https://www.youtube.com/watch?v=45L89MaJ7qA Abstract Background: Gain of function disturbances in nutrient sensing are likely the largest component in human age-related disease. Mammalian target of rapamycin complex 1 (mTORC1) activity affects health span and longevity. The drugs ketamine and rapamycin are effective against chronic pain and depression, and both affect mTORC1 activity. Our objective was to measure phosphorylated p70S6K, a marker for mTORC1 activity, in individuals with psychiatric disease to determine whether phosphorylated p70S6K could predict medication response. Methods: Twenty-seven females provided blood samples in which p70S6K and phosphorylated p70S6K were analyzed. Chart review gathered biometric measurements, clinical phenotypes, and medication response. Questionnaires assessed anxiety, depression, autism traits, and mitochondrial dysfunction, to determine neuropsychiatric disease profiles. Univariate and multivariate statistical analyses were used to identify predictors of medication response. Results: mTORC1 activity correlated highly with both classical biometrics (height, macrocephaly, pupil distance) and specific neuropsychiatric disease profiles (anxiety and autism). Across all cases, phosphorylated p70S6K was the best predictor for ketamine response, and also the best predictor for rapamycin response in a single instance. Conclusions: The data illustrate the importance of mTORC1 activity in both observable body structure and medication response. This report suggests that a simple assay may allow cost-effective prediction of medication response. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206033 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, ketamine, lithium, monocyte, mTORC1, rapamycin About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

In this episode of the Epigenetics Podcast, we talked with Mitinori Saitou from Kyoto University about his work on germ cell development, focusing on proteins like BLIMP1 and PRDM14, reprogramming iPSCs, and his vision to address infertility and genetic disorders through epigenetic insights. To start our discussion, Dr. Saitou shares the foundation of his research, which centers on the mechanisms of germ cell development across various species, including mice, non-human primates, and humans. He provides insight into his early work examining the roles of two key proteins: BLIMP1 and PRDM14. These proteins are essential for germline specification in mammals, and their functions are unveiled through detailed exploration of knockout models. In particular, Dr. Saitou elucidates the critical events in germ cell specification, highlighting how disruptions to the functions of these proteins lead to significant impairments in development. As the conversation deepens, we discuss Dr. Saitou's groundbreaking advances in human-induced pluripotent stem cells (iPSCs). He elaborates on the processes involved in reprogramming these cells to form primordial germ cell-like cells, emphasizing the significance of understanding various cellular contexts and transcriptional regulation. Dr. Saitou then details how overexpression of certain factors in embryonic stem cells can induce these germline characteristics, presenting the promise of innovation in regenerative medicine and reproductive biology. We end our talk with the exploration of chromatin remodeling that occurs during germ cell development, including fascinating details about DNA and histone modification dynamics. Dr. Saitou articulates how the epigenetic landscape shifts during the transition from pluripotent states to germ cell specification, providing a detailed comparison between mouse and human systems. This highlights the complexity of gene regulation and the importance of specific epigenetic markers in establishing and maintaining cellular identity.   References Yamaji, M., Seki, Y., Kurimoto, K. et al. Critical function of Prdm14 for the establishment of the germ cell lineage in mice. Nat Genet 40, 1016–1022 (2008). https://doi.org/10.1038/ng.186 Katsuhiko Hayashi et al., Offspring from Oocytes Derived from in Vitro Primordial Germ Cell–like Cells in Mice. Science 338, 971-975 (2012). DOI: 10.1126/science.1226889 Nakaki, F., Hayashi, K., Ohta, H. et al. Induction of mouse germ-cell fate by transcription factors in vitro. Nature 501, 222–226 (2013). https://doi.org/10.1038/nature12417 Nakamura, T., Okamoto, I., Sasaki, K. et al. A developmental coordinate of pluripotency among mice, monkeys and humans. Nature 537, 57–62 (2016). https://doi.org/10.1038/nature19096 Murase, Y., Yokogawa, R., Yabuta, Y. et al. In vitro reconstitution of epigenetic reprogramming in the human germ line. Nature 631, 170–178 (2024). https://doi.org/10.1038/s41586-024-07526-6   Contact Epigenetics Podcast on X Epigenetics Podcast on Instagram Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Epigenetics Podcast on Threads Active Motif on X Active Motif on LinkedIn Email: podcast@activemotif.com

This episode of the Real Science Exchange podcast was recorded during a webinar from Balchem's Real Science Lecture Series. Choline was discovered in 1862 in pig and ox bile (“chole” in Greek). It is a simple nutrient containing five carbons and a nitrogen. Choline is considered a quasi-vitamin since its requirements and de novo synthesis are both higher than the B vitamins it's similar to. Pigs can synthesize more choline than chickens. Choline is considered to be a conditionally essential nutrient depending on the physiological stage and choline production ability of the species being considered. (3:29)Choline is involved in cellular maintenance and growth at all life stages. In particular, it's involved in neurotransmission as a component of both sphingomyelin and acetylcholine. Phosphatidylcholine is a major component of cellular and organelle membranes and is involved in lipoprotein synthesis for the transport of lipids. Choline is converted to betaine upon oxidation, and betaine plays an important role in one-carbon metabolism as a methyl group donor. (8:43)Dietary-free choline is preferentially used for acetylcholine and phosphatidylcholine synthesis. Phosphatidylcholine is the most abundant form of choline in the body. In general, water-soluble forms of choline are absorbed faster and have a higher tissue incorporation rate than lipid-soluble forms. (14:58) Clinical signs of choline deficiency include reduced growth and reproductive performance. In pigs and chickens, choline-deficient diets lead to lipid accumulation in the liver. In broiler chickens, perosis is a classic choline deficiency sign and may progress to slipped tendons. From human studies, we know that insufficient methylation capacity during early development increases the risk of neural tube defects and impaired cognitive function. (16:44)As animals age, their dietary source of choline transitions from water-soluble forms to lipid-soluble forms. Mammalian young receive water-soluble choline from milk, and avian species from the egg yolk. After weaning in pigs and at the hatch in chickens, the dietary choline source transitions to lipid-soluble forms found in oilseed meals. Dr. Dilger goes on to describe choline concentrations in common feedstuffs and supplements. Feedstuff type and processing methods have a profound influence on bioavailable choline content. (19:16)Dr. Dilger details some of his work with choline and betaine in poultry diets. The requirement for preformed choline is relatively high for poultry because they lack capacity in a particular methyl transferase enzyme responsible for de novo synthesis. They also have relatively high choline oxidase activity which favors the formation of betaine from choline. Betaine is critical as a buffer to counteract the toxic effects of uric acid in the avian kidney. Dr. Dilger describes choline dietary requirements for avian species. (27:38)Pigs have more efficient methyl transferase activity for de novo synthesis of choline. Sufficient choline is provided by milk and practical diets. For growing pigs consuming corn-soybean meal diets where methionine can completely spare choline, there is little benefit of choline supplementation for growth. Choline requirements increase for gestating and lactating sows. Swine requirements for choline were set in the 1940s and 1950s. Dr. Dilger believes these requirements need a second look given the great changes in pig and crop genetics since the requirements were originally established. To that end, work in his lab has shown that choline intake during gestation and lactation influences sow milk composition, body choline concentrations and forms, metabolomic profiles and brain development of pigs. (35:18)In conclusion, Dr. Dilger considers choline a pervasive nutrient due to its crucial metabolic roles. Species-specific idiosyncrasies drive choline requirements, and analytical data for choline-related compounds is lacking. Different forms of choline have different metabolic kinetics and the potential for choline deficiency remains a practical issue. (46:15)In closing, Dr. Dilger answers an extensive set of questions from the audience. Watch the full webinar at balchem.com/realscience. (48:32)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

Dr. Kendall Calhoun of UCLA and UC Davis joins us to discuss the impact of megafires on wildlife communities. We delve into what defines a megafire, explore his research on wildlife and habitat responses to megafires, and discuss both the positive and negative effects of these events.   Resources: Calhoun, K. L., et al. (2024). Movement behavior in a dominant ungulate underlies successful adjustment to a rapidly changing landscape following megafire. Movement Ecology, 12(1), 53. Calhoun, K. L. et al. (2023). Mammalian resistance to megafire in western US woodland savannas. Ecosphere, 14(7), e4613. Calhoun, K. L. et al.  (2022). Spatial overlap of wildfire and biodiversity in California highlights gap in non‐conifer fire research and management. Diversity and Distributions, 28(3), 529-541. Kreling, S. E. et al.  (2021). Site fidelity and behavioral plasticity regulate an ungulate's response to extreme disturbance. Ecology and Evolution, 11(22), 15683-15694.   Dr. Kendall Calhoun @kenleecalhoun, @kenleecalhoun,  Academic Profile Dr. Carolina Baruzzi @wildlandmgmt, Academic Profile Dr. Marcus Lashley @DrDisturbance, Academic Profile   Have suggestions for future episodes? Send us your feedback! (here) Check out our newest podcast, Wild Turkey Science! Enroll now in our free, online fire course. Available to all. This podcast is supported by listener donations - thank you for being a part of this effort. For more information, follow UF DEER Lab on Instagram, Facebook, Twitter, YouTube.   Music by Dr. David Mason and Artlist.io Produced and edited by Charlotte Nowak  

Dr. Kendall Calhoun of UCLA and UC Davis joins us to discuss the impact of megafires on wildlife communities. We delve into what defines a megafire, explore his research on wildlife and habitat responses to megafires, and discuss both the positive and negative effects of these events.   Resources: Calhoun, K. L., et al. (2024). Movement behavior in a dominant ungulate underlies successful adjustment to a rapidly changing landscape following megafire. Movement Ecology, 12(1), 53. Calhoun, K. L. et al. (2023). Mammalian resistance to megafire in western US woodland savannas. Ecosphere, 14(7), e4613. Calhoun, K. L. et al.  (2022). Spatial overlap of wildfire and biodiversity in California highlights gap in non‐conifer fire research and management. Diversity and Distributions, 28(3), 529-541. Kreling, S. E. et al.  (2021). Site fidelity and behavioral plasticity regulate an ungulate's response to extreme disturbance. Ecology and Evolution, 11(22), 15683-15694.   Dr. Kendall Calhoun @kenleecalhoun, @kenleecalhoun,  Academic Profile Dr. Carolina Baruzzi @wildlandmgmt, Academic Profile Dr. Marcus Lashley @DrDisturbance, Academic Profile   Have suggestions for future episodes? Send us your feedback! (here) Check out our newest podcast, Wild Turkey Science! Enroll now in our free, online fire course. Available to all. This podcast is supported by listener donations - thank you for being a part of this effort. For more information, follow UF DEER Lab on Instagram, Facebook, Twitter, YouTube.   Music by Dr. David Mason and Artlist.io Produced and edited by Charlotte Nowak

Two mammals made a visit to Laura's yard on Sunday night.

IHP YouTube video podcast episode made available to our other IHP podcast platforms. IHP content is for people who are interested in topics, stories, & guidance for personal development, self-help, spirituality journey, the 5D mystic path, & enlightenment the human way. It's for those who choose the human love narrative, not the human suffering narrative. Don't tune in if you don't love life and humanity because this won't be for you. Don't tune in if you still believe in evil or the devil. Topic not ideal for ego-sensitive or emotionally sensitive (on any/all life - including socio-pol-eco - topics) people. Please do not tune in. Thank you! All IHP content resonates with people who want to achieve enlightenment the human way. IHP podcast host Maria Florio shares voices, stories and perspectives from her 5D mystic enlightenment functional adult life to give examples of what it's like to know emotional self-regulation skills, experience secure attachment, have functional adult conversations and experience 5D relationships (5D and beyond vibing people). You hear about how easy it is to be yourself, to pursue inner growth, to unconditionally love, to have compassion, and live your best life with outer and inner-well being in the forefront. Also explored, how to communicate and handle emotionally insecure adaptive children grown ups, the 3D or 4D vibing individuals, those who stay within insecure emotional human suffering vibration experience and mindset, or who hold drama as the go-to in relationships, or use projection due to unresolved and unaddressed trauma, attachment wounds, and inner child wounds that come up in their behavior. Since trauma is relational and intimacy necessary to heal it, through Maria's stories and perspectives people get an idea of securely attached options on how to handle projection to the best of your ability and create a safe environment for another person to heal or for you to set a healthy boundary if the person bringing the projection (3D/4D drama vibe) is not seeking to move beyond their safety behavior/unresolved trauma emotional response. All of what we do in our day-to-day relationships, conversations, and interactions can bring the potential for healing and expansion of consciousness. The content is for people who are or want to be self-aware, accountable & want to establish functional adult secure attachment emotionally mature behaviors & relationships in life. Your humanity is living a life of meaning & connection beyond the solo-self, as is the true spirituality life. We welcome all people of all walks of life to reclaim their inner child & live their inner child adult, to pursue integration of the brain & restorative embodied self-aware life in time & through healthy self-worth functional adult secure attachment 5D relationships. IHP podcast host Maria Florio shares voices, stories & perspectives from her 5D mystic enlightenment functional adult life to give examples of what it's like to know emotional self-regulation skills, experience secure attachment, have functional adult conversations & experiences & 5D relationships. This and more is what the IHP content and community is all about. Welcome and thanks for tuning in! Love, Maria, your 5D mystic enlightenment functional adult woo-woo pseudoscience lady IHP podcast host talking about the amazing journey of human evolution & consciousness♾️

Born and raised in Hokkaido, Japan, Professor Ryuzo Yanagimachi, the 2023 Kyoto Prize Laureate in Basic Sciences, developed a love for nature. He became fascinated with the fertilization process of sea urchins. After studying the fertilization of fish and the life cycle of parasitic barnacles, he realized little was known about mammalian fertilization. He went on to train with Professor M.C. Chang at the Worcester Foundation for Experimental Biology, the father of mammalian in vitro fertilization and then started his own lab at the University of Hawai'i. His basic studies contributed to understanding the hidden capacity of sperm and eggs and overcoming human fertility problems. Professor Yanagimachi passed away in 2023 at the age of 95, just a few months before he was to receive his Kyoto Prize award. Dr. W. Steven Ward, Director of the Institute for Biogenesis Research at the University of Hawai'i will present Prof. Yanagimachi's life and work. Series: "Kyoto Prize Symposium" [Health and Medicine] [Science] [Show ID: 39423]

Born and raised in Hokkaido, Japan, Professor Ryuzo Yanagimachi, the 2023 Kyoto Prize Laureate in Basic Sciences, developed a love for nature. He became fascinated with the fertilization process of sea urchins. After studying the fertilization of fish and the life cycle of parasitic barnacles, he realized little was known about mammalian fertilization. He went on to train with Professor M.C. Chang at the Worcester Foundation for Experimental Biology, the father of mammalian in vitro fertilization and then started his own lab at the University of Hawai'i. His basic studies contributed to understanding the hidden capacity of sperm and eggs and overcoming human fertility problems. Professor Yanagimachi passed away in 2023 at the age of 95, just a few months before he was to receive his Kyoto Prize award. Dr. W. Steven Ward, Director of the Institute for Biogenesis Research at the University of Hawai'i will present Prof. Yanagimachi's life and work. Series: "Kyoto Prize Symposium" [Health and Medicine] [Science] [Show ID: 39423]

Born and raised in Hokkaido, Japan, Professor Ryuzo Yanagimachi, the 2023 Kyoto Prize Laureate in Basic Sciences, developed a love for nature. He became fascinated with the fertilization process of sea urchins. After studying the fertilization of fish and the life cycle of parasitic barnacles, he realized little was known about mammalian fertilization. He went on to train with Professor M.C. Chang at the Worcester Foundation for Experimental Biology, the father of mammalian in vitro fertilization and then started his own lab at the University of Hawai'i. His basic studies contributed to understanding the hidden capacity of sperm and eggs and overcoming human fertility problems. Professor Yanagimachi passed away in 2023 at the age of 95, just a few months before he was to receive his Kyoto Prize award. Dr. W. Steven Ward, Director of the Institute for Biogenesis Research at the University of Hawai'i will present Prof. Yanagimachi's life and work. Series: "Kyoto Prize Symposium" [Health and Medicine] [Science] [Show ID: 39423]

Born and raised in Hokkaido, Japan, Professor Ryuzo Yanagimachi, the 2023 Kyoto Prize Laureate in Basic Sciences, developed a love for nature. He became fascinated with the fertilization process of sea urchins. After studying the fertilization of fish and the life cycle of parasitic barnacles, he realized little was known about mammalian fertilization. He went on to train with Professor M.C. Chang at the Worcester Foundation for Experimental Biology, the father of mammalian in vitro fertilization and then started his own lab at the University of Hawai'i. His basic studies contributed to understanding the hidden capacity of sperm and eggs and overcoming human fertility problems. Professor Yanagimachi passed away in 2023 at the age of 95, just a few months before he was to receive his Kyoto Prize award. Dr. W. Steven Ward, Director of the Institute for Biogenesis Research at the University of Hawai'i will present Prof. Yanagimachi's life and work. Series: "Kyoto Prize Symposium" [Health and Medicine] [Science] [Show ID: 39423]

During labor, you want contractions that are longer, stronger, and closer together. But why? Dr. Sarah Buckley and Adriana take a deep dive into the amazing and fascinating hormonal dance that happens during the birthing process, and how interventions such as synthetic oxytocin or an epidural can lead to a cascade of interventions that negatively impact the process for both the birthing person and their baby. They also talk about ways to support the physiology of birth (regardless of what path it takes) in order to help fill any ‘hormonal gaps' that may occur.Sponsor offers - TIME SENSITIVE! NEEDED - Get 20% off at ThisIsNeeded.com with code BIRTHFULHONEYLOVE - Get 20% off at HoneyLove.com/Birthful JENNI KAYNE - Get 15% off at JenniKayne.com/Birthful with code BIRTHFUL15ONESKIN - Get 15% off at https://www.OneSkin.co/ with code BIRTHFULFAMILYALBUM APP - Download the app for free, wherever you get your apps! MY LIFE IN A BOOK - Get 10% off at MyLifeInABook.com with code BIRTHFULAQUATRU - Get 20% off at AquaTru.com with code BIRTHFULGet the most out of this episode by checking out the resources, transcript, and links listed on its show notes page.  If you liked this episode, listen to our interview on Your Baby, The Mammal and our episode on How to Avoid a "Cascade of Interventions".You can connect with Sarah on Facebook at drsarahbuckley. You can connect with us on Instagram at @BirthfulPodcast and email us at podcast@Birthful.com. If you enjoy what you hear, download Birthful's Postpartum Plan FREE when you sign up for our weekly newsletter! You can also sign up for Adriana's Own Your Birth online BIRTH preparation classes and her Thrive with Your Newborn online POSTPARTUM preparation course at BirthfulCourses.com.Follow us on Goodpods, Apple Podcasts, Amazon Music, Spotify, and anywhere you listen to podcasts.Our Sponsors:* Check out mylifeinabook.com and use code BIRTHFUL at checkout for 10% off. Create an unforgettable gift for your mom this Mother's Day.* Visit HomeThreads.com/BIRTHFUL today and get a 15% off code for your first order!Support this podcast at — https://redcircle.com/birthful/donationsAdvertising Inquiries: https://redcircle.com/brands

Peach fuzz. Chin hairs. Mammalian ponytails. WHY DO THEY HAPPEN. Yale researcher and associate professor Dr. Valerie Horsley stops by California to chat with Alie about the nature of hair and what it has to do with skin and nails, stem cells, how it grows, why some of us have curly hair or straight hair or thin hair or thick hair, and why we love and hate and need our hair as animals.Dr. Valerie Horsely is on FacebookThe Horsely Lab at YaleMore episode sources & linksFull-length (*not* G-rated) Trichology episode + tons of science linksMore kid-friendly Smologies episodes!Become a patron of Ologies for as little as a buck a monthOlogiesMerch.com has hats, shirts, hoodies, totes!Follow @Ologies on X and InstagramFollow @AlieWard on X and InstagramSound editing by Mercedes Maitland of Maitland Audio Productions and Steven Ray MorrisMade possible by work from Noel Dilworth, Susan Hale, Kelly R. Dwyer & Erin TalbertSmologies theme song by Harold Malcolm

Dr. Nicolas Glynos received his PhD in Molecular & Integrative Physiology from the University of Michigan, where he studied the psychedelic drug DMT in the mammalian brain. They discuss: the history of DMT research; the use of DMT in ayahuasca; whether DMT is found endogenously in animals; why plants produce DMT; pineal gland, DMT & melatonin; the latest research looking at the presence and effects of DMT in the brain; and more.More M&M content about psychedelics: https://substack.com/search/psychedelics?focusedPublicationId=513528&searching=focused_posts#psychedelics #DMT #science #neuroscience #podcast #serotoninSupport the showFind all podcast & written content at the M&M Substack:[https://mindandmatter.substack.com]Learn how to further support the podcast: [https://mindandmatter.substack.com/p/how-to-support-mind-and-matter]Try Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.Try SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount.Try the Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for $50 off...

References General and Comparative Endocrinology,2018-06-01, Volume 262, Pages 27-35 Pisendel JG 1735.Violin Concerto in D major, JunP I.5. https://youtu.be/dvwhXXvFiNg?si=YfS2waKLC5WHy0En --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References General and Comparative Endocrinology 2018-06-01, Volume 262, Pages 27-35. Immunohorizons. 2022 Jun 22; 6(6): 366–372. Biochem J. 2009 Dec 14;425(1):265-74. Nature. 2023; 614(7948): 530–538. Winwood,S. 1969 Blind Faith "Had to Cry Today". https://youtu.be/Z4Yo_VbGdMg?si=3whbMcoWNFtfgPwE --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

In this episode of Quah (Q & A), Sal, Adam & Justin answer four Pump Head questions drawn from last Sunday's Quah post on the @mindpumpmedia Instagram page.  Mind Pump Fit Tip: The next time you hear a diet/fitness influencer say reverse dieting doesn't work, turn them off, they are morons. (2:00) Highlighting how much we strive for the recognition of our peers. (12:20) The power of genetics. (23:38) The ultimate performance stack from Organifi. (32:25) Loving your kid more than yourself. (33:34) Love is an action. (39:20) Sal's new TRT strategy. (47:14) Butcher Box's CRAZY Black Friday deal. (52:55) Is the human extinction movement a real thing? (56:39) Shout out to Edgar Goulas. (58:39) #Quah question #1 - What do the different foot and leg positions work on a leg press machine? (1:00:48) #Quah question #2 - Is it possible to increase BMR beyond what traditional calculators say simply with reverse dieting and strength training? (1:07:04) #Quah question #3 - Is cold plunging post-workout worth the tradeoff of blunting the muscle-building signal if it leads to better recovery, and therefore, more frequency and volume? (1:09:50) #Quah question #4 - Did you all train while in London? What did your nutrition look like? What new foods did you guys try? (1:16:01) Related Links/Products Mentioned Visit Organifi for the exclusive offer for Mind Pump listeners! **Promo code MINDPUMP at checkout** Visit Butcher Box for this month's exclusive Mind Pump offer! November Promotion: MAPS Resistance | MAPS Prime Pro 50% off! **Code NOVEMBER50 at checkout** Mammalian metabolism photo Mind Pump #1915: How To Re-Ignite Your Metabolism Planet Fitness Unexpectedly Fires its CEO, and Shares Plunge Doppelgängers Don't Just Look Alike—They Also Share DNA Three Identical Strangers The Weird Mental Frameworks Of The Super Rich - Codie Sanchez | Modern Wisdom 695 TRANSCEND your goals! Telehealth Provider • Physician Directed GET YOUR PERSONALIZED TREATMENT PLAN!  Hormone Replacement Therapy, Cognitive Function, Sleep & Fatigue, Athletic Performance and MORE. Their online process and medical experts make it simple to find out what's right for you. Earth Now Has 8 Billion Humans. This Man Wishes There Were None. Jonathan Pageau encourages World Leaders to pursue the supreme Good Visit Hiya for an exclusive offer for Mind Pump listeners! How to do a Bulgarian Split Squat - YouTube Front Squats- How to Place & Hold the Bar - YouTube THIS Is The BEST Side Butt Exercise! - YouTube MAPS Macro Calculator Visit The Cold Plunge for an exclusive offer for Mind Pump Listeners! **Promo code MINDPUMP at checkout for $150 off your order** Mind Pump #1822: Wim Hof On How To Control Your Immune System With Breathwork Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Elon Musk (@elonmusk) X Drew Canole (@drewcanole) Instagram Chris Williamson (@chriswillx) Instagram Codie Sanchez (@codiesanchez) Instagram Dr. Dwayne N. Jackson, PhD (@drdnjackson) Instagram Jonathan Pageau (@jonathan.pageau) Instagram Edgar Goulas (@eddy_teddy21) Instagram Justin Brink DC (@dr.justinbrink) Instagram Wim Hof (@iceman_hof) Instagram

What if you were given the key to understanding your own emotions and behavior? Prepare to venture on a fascinating exploration of the human brain with our esteemed guest Loretta Breuning Ph.D, the founder of the Inner Mammal Institute, an author of 8 books, and a  host of The Happy Brain podcast. We delve into the power of brain chemicals - serotonin, dopamine, oxytocin, and endorphins and the impact of childhood experiences on our neural development, and strategies for managing our emotions. We're not stopping there. We're also diving deep into the role of cortisol - the stress hormone often overlooked in discussions about emotions. We examine our responses to fear and survival, and how these are linked to our evolution. Moreover, we provide practical tips on how to relieve cortisol and shed light on how our brain's operating system functions. In the latter stages, we navigate the complex terrain of negative thoughts, pursuits, and disappointments, expectation setting, unraveling how these scenarios impact our neural pathways. We also discuss the differences in behavior between men and women from an evolutionary perspective, and how our expectations are directly linked to our dopamine levels. Join us as we reveal the power of creating new neural pathways, even in the face of fatigue or hardship. This episode is an essential listen for anyone wanting to decode the intricate science behind our emotions and behavior.Resources: Habits of a Happy Brain: Retrain Your Brain to Boost Your Serotonin, Dopamine, Oxytocin, and Endorphin LevelsThe Happy Brain PodcastInner Mammal InstituteReading ListAnger Management: I Feel PrettyNOBLE COLD PLUNGE Noble Cold Plunge creates health benefits through a hormetic stress response. Save $250 with GSJ2508 EIGHT SLEEP Save $250 on 8Sleep and get better quality and deeper sleep with automatic temperature adjustmentTESLA Use my referral link for Tesla and get up to $250 off and 3-months of Full Self-Driving CapabilityDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Thank you for listening. If you enjoyed this episode, share it with someone who may enjoy it as well, and consider leaving a review on Apple Podcasts & Spotify. You can also submit your feedback directly on my website. Follow @GrandSlamJourney on Instagram, Facebook, Twitter or join the community on LinkedIn. This content is also available on Substack and YouTube.

Having ADD or ADHD is a gift, not a curse. Hear from people all around the globe, from every walk of life, in every profession, from Rock Stars to CEOs, from Teachers to Politicians, who have learned how to unlock the gifts of their ADD and ADHD diagnosis, and use it to their personal and professional advantage, to build businesses, become millionaires, or simply better their lives.  Our Guest today in her own words:  Suzy Malseed is a high-energy Mum of twins, a competitive free-diver, a farmer, a reformed teacher and a neurodiversity advocate. Based in Australia, originally from New Zealand, Suzy maintains a ferocious appetite for adventure and travel, having lived in 6 countries and worked and stayed in many more! We have a few things in common, but can you guess the main similarity? Yep, ADHD! Also parachutes; but you've got to subscribe and listen for that story ;-)  Enjoy and hey, thanks so much for subscribing to Faster Than Normal!  [you are now safely here ]    00:40 - Thank you again so much for listening and for subscribing! [This week we've switched to Cloudemagic.io from a slow Descript. All sorts of things are happening in Tech now, huh?!  This may be ‘the way' we go for this upcoming Summer season. Please let us know what you think in the comments?! I will be paying special attention to any feedback on this Ep, that you may share- and also of the past three Ep.s (not the tbd Ep.291)  Thank you -Ed] 01:00 - Introducing and welcome Suzy Malseed!  03:50 - Most parents when their kids are diagnosed are like, Wait- this sounds like me? 05:09 - Shrek- Ogers are like Onions Ref 06:00 - On processing your ADHD 06:37 - Peter on Free Diving. Ref: Le Grande Blue  Luc Besson [Not a Luc Besson film, but if you love the above ref, (or Philip Glass, or Portugal even, then this assistant editor strongly rec's The 100 Foot Wave. It appears to also be a podcast now! -Ed] 07:50 - On “the silence” while free diving with very little gear  Ref:  If I dive to 30 meters, that four times the pressure that we experience walking on the ground..feels like a giant bear hug, basically.  09:24 - On Skydiving joy 09:42 - do you have techniques to get your head right, to get into the zone & ready to dive? 10:52 - On meditation.  11:00 - How much does your heat rate decease when you put just your HEAD into the water? Ref: The Diving Reflex aka MDR 11:18 - What, what? Why?? Genetics??! 12:05 - On mental and physical adaptation & breaking the surface13:04- Are you good in Emergencies too? Please ell us in the comments!! [remember, we always read these at some point every few weeks] 14:04 - Is dopamine generation = wanderlust or/and wanderlust?  [US parlance + vernacular]  14:20 - What else do I and we all not know about Free Diving; but should? 16:32 - When your back-up plan is to be prepared and try harder if… there is a next time, 98 feet down. 17:26 - Do you want to see what free diving in an Underwater Cave looks like?! [We have warned you!! [Trusted respect to AL + MCH & Co. btw -Ed ;-] 18:10 - Thank you Suzy Malseed!!  “I would rather a child start therapy at an early age and learn that they're brilliant; than spend the next 30 years undoing the belief that they are broken.”  -Peter Shankman  June 7, 2023 18:14 -  How do our now Summer-shiney subscribers find out more about you?  Web:  Will update if avail. Otago Times article from 2018 is here Socials: @NoAirSuzy on:  INSTA  @SuzyMalseed on: Facebook 18:14 - Hey, you there! Yes YOU! We are thrilled that you are here & listening!  ADHD and all forms of Neurodiversity are gifts, not curses. And by the way, if you haven't picked up The Boy with the Faster Brain yet, it is on Amazon and it is a number one bestseller in all categories. Click HERE or via https://amzn.to/3FcAKkI My link tree is here if you're looking for something specific. https://linktr.ee/petershankman 17:24 - Faster Than Normal Podcast info & credits. Guys, as always thanks so much for subscribing! Faster Than Normal is for YOU! We want to know what you'd like to hear! Do you have a cool friend with a great story? We'd love to learn about, and from them. I'm www.petershankman.com and you can reach out anytime via email at peter@shankman.com or @petershankman on all of the socials. You can also find us at @FasterNormal on all of the socials. It really helps when you drop us a review on iTunes and of course, subscribe to the podcast if you haven't already! As you know, the more reviews we get, the more people we can reach. Help us to show the world that ADHD is a gift, not a curse!  [ Ed: This is a relatively brand new experiment in editing show notes, transcriptions sort of; so if you notice any important, or significant goofs we've missed here or along, please do let us know @FasterNormal  Thanks! -sb]    EXTRA CREDIT:  10 GEN-AI POINTS ABOUT FREE DIVING COVERED IN THIS INTERVIEW AND GENERATED BY AI.  1. What is free diving?  Ref: Free Diving Safety  Answer: Free diving is an activity that involves diving underwater without the aid of scuba diving equipment, but instead, relying on one's ability to hold their breath and adapt to high pressure underwater. 2. What is the process involved in free diving? Answer: The process involves a state of deep meditation to connect the mind, body, and breath. It involves getting a feeling in the body to confirm readiness and experiencing a mammalian dive reflex, which results in a 30% drop in heart rate when immersing the face in water. 3. What attracts people to free diving? Answer: Many free divers are drawn to the sport due to the sensory deprivation it offers. The sport also requires a lot of respect for the body and its ability to adapt to the demands of the sport. 4. What is the connection between ADHD and free diving? Answer: ADHD is highly represented in free diving. Many free divers with ADHD are drawn to the sport's calming effect and the sensory deprivation it offers. 5. Can free diving be a solo activity? Answer: Yes, free diving can be a solo activity, and the responsibility for success or failure rests solely on the diver. 6. What is the movie La Grand Blue about, and why is it significant? Answer: La Grand Blue is a movie about a free diver who can slow down his heartbeat and go as deep as he wants. It is one of Luke Basal's best films and launched the career of Eric Sierra and Jean Renault. 7. How does free diving compare to skydiving? Answer: Both skydiving and free diving require a lot of preparation work before the activity. The speaker puts a lot of effort into checking their gear before skydiving and even dreams about it. 8. What is the connection between risk-taking and neurodiversity? Answer: The speaker shares a love for risk-taking with their son. They both enjoy taking risks, but they are careful when doing so. This high appetite for risk-taking is much higher than the average person. 9. How was the speaker's son diagnosed with developmental issues? Answer: The speaker's son was diagnosed with developmental issues by a specialist in Singapore who observed his high energy and sensory needs. 10. Why is silence important to the speaker in free diving? Answer: The speaker experienced silence for the first time in their life when they first went underwater, and they are addicted to the quiet. The feeling of deep pressure on their body when diving is also compared to a welcoming hug. — TRANSCRIPT via Castmagic.io and then corrected.. somewhat, (Ooh-ooh! Fourth and likely final trial run is today June 7, 2023. #gen_AI_for_whut?? Peter Shankman [00:00:40]: Ladies and gentlemen, good morning from wherever in the world you happen to be. And welcome to their episode of Faster Than Normal. My name is Peter Shankman. It is 5:30 in the morning when I am recording this, which can only mean one thing. We are talking to someone and interviewing someone on the other side of the world, because otherwise I'd be on my bike right now. I want you guys to meet Suzy Malseed. Suzy is with us today, who is a high energy mom of twins, or Mum, as she puts it, which cold give you some idea of where we're talking to get this. She's a competitive free diver. I cannot wait to talk about that! She's a farmer, a reformed teacher, a neurodiversity advocate. She is based in Australia. Her two kids have ADHD. She's originally from New Zealand. She believes she has ADHD. She's a ferocious appetite for adventures and travel, having lived in six countries and worked and stayed in many more. Susie, good evening. Where you are. Good morning from where we are! Suzy [00:01:26]: Hello, Peter!! How are you? Peter Shankman [00:01:28]: It is great to have you back on the podcast. Love to talk with this. I found you because I started following you on Instagram because your Instagram is just you free diving, which is just some cool stuff. So I'm a huge fan. So thanks for taking the time today. Suzy [00:01:42]: Thank you very much. Thanks for having me. Peter Shankman [00:01:44]: So there are a lot of topics here I want to cover. Both your children, ADHD, were they diagnosed? If so, where? If so, how? How old are they? Let's start the so. Suzy [00:01:55]: Yeah, my kids are twins and they were diagnosed pretty young, particularly my son. So he was diagnosed first, which is kind of often the case because girls present a little differently. And he was diagnosed pretty early, pretty easily, pretty obvious, if you know what I mean. Right, Add? It wasn't necessarily something that I sort of went to the doctors and said, look, I think we've got some challenges. It was actually more because they were twins and because they were a little bit premy and we were living in Singapore at the time. Oh, wow. Yeah. And so singapore is amazing. It tends to be a little bit more on the clinical side, so they're very good at tracking and than sort of thing. So they were tracking growth and checking up a lot of things. And it was actually only in quite a routine sort of pediatric appointment when the specialist just saw my son literally bouncing and just said and I just said, oh, no, he's got high energy. I have too. And they just said, yeah, but there's energy and then there's energy. And I just went, oh, okay. Anyway, so we went there with Max pretty quickly, and it helped him a lot, to be honest, because it helped us to understand his sensory needs. That was probably the biggest thing that we had to get our heads around, is his sensory needs. He was very sensitive, so there was a lot of sort of putting his fingers in the ears and high pitched noises. He was very aversive to those sort of things. But he was also a sensory seeker, so he would love contact. He would love heavy contact. And once we understood that, we could do a lot of OT him. And we did a lot of physical work with him. I ran everywhere with him, on him, a scooter and a skateboard in the pool from a very young age, and his body just responded just so well to that heavy work. So I'm very grateful for understanding…. Peter Shankman [00:03:49]: Interesting. You said than you're undiagnosed, but you probably have it like most parents when their kids are diagnosed. That's how you figured out. You're like, Wait, this sounds like me 100%. Suzy [00:04:01]: I mean, as I was reading reading to learn more, to understand how to advocate for my son, I just sort of went, oh, my God. Well, that's me. And it was sort of the risk taking type stuff. I've never really put it all together, but I'm a very high energy person. I always have been. I've always had a ridiculous appetite for risk, but not in a stupid way. So from the outside, it might look like you're doing crazy stuff, but I've actually thought about everything I've done before I've done it. But my appetite for risk is certainly much higher than the average person. And I saw it with my son as well. He would jump off very high things, but he knows how to land, and that's the difference, right? Little parachute landing, and he's just not scared of getting hurt. And I've had the same thing. I'm not scared of getting hurt, which is probably quite weird, but when you've lived your whole life in the same body, you don't really realize how strange it is until you sort of put it all together. And it's like peeling an onion. As you get older, you realize a little bit more every year. Peter Shankman [00:05:09]: I always think back to that great line in Shrek. Onions are like ogres. Oh, they smell. No, they have layers. But it's very true. It's a complicated peel. It's interesting. And I talk about this all the time, which is great segue into talking about free diving. I never felt any kind of sense of release until I did my first race, until I did my first skydive, until I did all these things that allowed me to get as much dopamine as I ever wanted than I was doing stuff that would get me in trouble in school. And it'd be a nice quick hit, but it'd always come with a punishment. So, yeah, when you find that thing, it changes everything. And I'm sure your kids figured that out. Suzy [00:05:46]: Oh, absolutely. And for me, when I was at school, I mean, being a female, it's different again, like, I was the class clown, like you sort of alluded to in your book and stuff as well. It's very similar. And I never realized that I was doing it. I wouldn't have said than I was doing it to get a laugh. I was just quite flippant, and my brain just goes so fast. I would think of things very quickly. And it did get me into a fair bit of trouble, of course, but yeah. And you do realize after a while I did figure out that I was chasing adrenaline. I didn't understand that I was also chasing dopamine. So there's been a lot more come out since. Every year we learn more. So that's an interesting bit to put together. Peter Shankman [00:06:26]: All right, speaking of dopamine, let us talk about free diving. How cool. I've never done it, but I actually can't. Funnily enough, I have something called a peritoneal shunt in my spine. I can't go below like 20ft or. Suzy [00:06:40]: I'll. Peter Shankman [00:06:42]: But let's talk about free diving. I first learned about free diving high, as I'm sure you're familiar with in the movie La Grande Blue. Yes, I saw that movie in college, Add. Holy shit. Did that just captivate the hell out of me. It started my love affair with Jean Renew. If you haven't seen La Grande Blue, it's one of Luke Basal's best films. Luke Basal is the guy who did the original of Fem Nikita. Not that American bullshit, but the original version, the French version. And La Grande blue launched Eric Sierra's career and launched Jean Renault's career as well. So I strongly encourage you to check out La Grand Blue. But it is about a free diver and who just has this incredible ability to go as deep as he wants and slow his heartbeat down like something like six beats a minute. The first question I want to ask it must be I'm sure the dope mean hit is amazing, but the silence must be incredible. Suzy [00:07:39]: Yes. This is the thing. When I first went underwater was the first time in my whole life I've ever experienced silence. Like, my whole mind just went quiet. And that is what I'm probably addicted to the most, is just the quiet. I just love it. And then there's also pressure. So you're familiar with every 10 meters of depth, there's an additional atmosphere of pressure on the body right. So when we're sort of walking around on the ground, we have 1 ATM of pressure on our body. When we go 10 meters below surface, we have two atmospheres of pressure. Every 10 meters past that is an additional. So if I dive to 30 meters, I have four atmospheres of pressure on my body. Four times the pressure that we experience on the walking around on the ground. Now that feels like a giant bear hug, basically. And the really interesting thing is you either like it or you don't like it, to be honest. And I love that feeling. It's deep pressure to me. It just feels like a big welcoming hug. And that's a sensory thing for sure. So I have a few head starts, I think in terms of my natural ability to be able to be very good at the sport, sort of just drew me in from the start because I've actually been helping other people along the way. And sometimes when I watch their journey, it seems so foreign to me because it was so different to my journey. So they tell me about how scary it is and they tell me all than and I'm just like I can see that they are scared, so it's their truth. But I don't understand it because I've never had any fear around free diving. For me, it's just the most beautiful sport you could ever do. Peter Shankman [00:09:24]: I think it's the same for Skydiving when I'm never more free. Because when I jump out of that plane, I only have two options. I'm going to live or I'm going to die. That's it. Yes. Suzy [00:09:34]: Quite a cool feeling, right? Peter Shankman [00:09:35]: It is. It's wonderful. It's the most free I'll ever be. Suzy [00:09:38]: Yeah.  Peter Shankman [00:09:42]: So one of the things about Skydiving, I'm assuming it's the same with Freediving, is there is a not of prep work that goes into it. And a lot of for me, it's checking my gear, it's making sure that everything's right. The point where I have dreams about it. And my parents, once when they came to, they weren't too happy I was doing it. But when they first came to watch me, they told me were shocked at how meticulous I was because I was never that meticulous for anything in my life. And all of a sudden I'm here checking all my gear and I'm doing double check and triple check. So I'm curious, do you have routines before you go? You don't just jump in the water and dive. So do you have things that you do to sort of get your head right, to get into that zone to get ready to go? Suzy [00:10:24]: Yeah. The cool thing with free diving is we don't have a lot of gear. So that's pretty cool. Compared to scuba diving or technical diving. They have a lot of gear. They have all of that check check stuff. We don't have that. But obviously we have to go through our own process. The process that I go through is basically I would consider it. I was very deep meditation. So it is my way of connecting in my mind, my body and my breath. I get a feeling in my body and then I know I'm okay, I'm ready. Everything's like you just quieten down, everything. And then your heart rate flows. It's called a mammalian dive reflex. So every human gets this. When you hop in the water and immerse your face you'll get a 30% drop in heart rate. That's a given, right? Everyone gets that? Yeah.  Peter Shankman [00:11:11]: Wow. When you're in the water say it again, say it again. Suzy [00:11:16]: So when you immerse your face in water you get a 30% drop in heart rate. Peter Shankman [00:11:22]: That is incredible. Why?! Suzy [00:11:24]:  It's genetic. So it goes back to when we were little, whatever you think we were before. A little fishy somewhere along the line. Yes. It's called the mammalian mammal. Mammalian dive reflex. MDR. Yes, I've heard of that. Peter Shankman [00:11:39]: Okay. Suzy [00:11:39]: Yeah, no I know! Peter Shankman [00:11:40]: 30%. That's amazing. Suzy [00:11:42]: It's a big drop and so that's a real thing. So that sense of comfort and feeling like you're really supposed to be there comes over you. And then of course I suppose one of the other reasons I just love the sport so much is how much your body adapts is just you have so much respect for your body. So your body can adapt to pressure. Obviously we take one breath at the surface and that breath has got to carry us through all of the equalizations of our masks, our sinuses, our ears all the way down to the bottom and then all the way back. And the more you dive, the more you free dive, the more your body adapts to what you're asking it to do. And that happens with everything that we do, as you would know with your own body and your training. And free diving is perhaps an extreme example of that because when you take your breath on the surface and you leave, it's just you and it's like jumping out of a plane. It's just you. There's no one to blame, it's no one else, it's just you. And like you said to me, it's just so freeing. I go very silent and very quiet in that response. And are you good in emergencies and things like that. Like do you have that same sort of response where whenever everyone else panic. Peter Shankman [00:13:04]: I'm perfect in emergencies I'm terrible at real life.  Suzy [00:13:07]: Exactly. Peter Shankman [00:13:08]: But throw an emergency there and I'm the guy you want. Suzy [00:13:11]: Correct? Yeah. And I'm exactly the same and I figured that out along my life as well. Everyone. And when I was a kid I used to tell myself, I don't know why, but I live in opposite land and that's just how I prioritize it on my head. So someone else would go yay, we're having a massive party. And I would go oh my god. Peter Shankman [00:13:28]: Exactly. Well you know, you just made me realize something. I think that part of that might be because when you're in an emergency, you don't have time for social anxiety. There's never any small talk in the emergency. Suzy [00:13:40]: True. Yeah. Peter Shankman [00:13:42]: I just realized that there's no small talk in emergency. It's get shit done now. Suzy [00:13:46]: Yes. And we can be who we really are, like instead of niceties. And the other one I wanted to touch with you is travel. So I know that you're a massive traveler and I'm the same and quite extreme stuff as well. Probably when I look back in it, I have an appetite for that. And I think it boils down to the same sort of really ridiculous survival instinct which I quite enjoy, which is basically you're only going to eat when you figure out how to go get the food that you want to get and how to make yourself understood. Peter Shankman [00:14:16]: That's kind of a cool thing very much. I love that. What else? What am I not asking you about? Freediving? I don't know enough about it to know what to ask you. What am I not asking? Suzy [00:14:29]: Okay, so I think that ADHD is quite highly represented in free diving, to be honest. When I consider other free divers and I look around I see a lot of people who are like me and I believe that we're all drawn to the sport for the same reason, which is like a form of sensory deprivation, if you know what I mean. A lot of times we're actually diving in black water and that freaks some people really out. But we just close our eyes and I suppose how do you do that? Well, you have to find a way to surrender. You have to understand than the more you relax, the better your dive will be, the more tense you are, the worse your dive will be. So you have to switch off and there really is no choice. And if anything happens when you're under the water like I've had a couple of little incidences along the way. I had this time when I was swimming through a wreck and it was a fun dive with some other free divers and as I was going through the wreck and coming up through the wheelhouse, the back of my fin came off and I was sort of like it just came over me. I'm like, oh my God, I'm 30 meters down. I've already been here for at least a minute and now I only have one fin. If I panic, I'm toast. And you just go through that process and you're like, right, I have to cross my legs to make you can picture yourself crossing your legs and than do the dolphin movement to make your one fin work and just get yourself to the surface fast. And you just know that you have no space for panic so you have to stay calm. Peter Shankman [00:16:10]: I'm panicking listening to that story and I get it. I mean, you're in a position like same thing with Skydiving. Knock on wood. I haven't had to use my reserve yet, 500 jumps, but I'm sure at some point I will and I'll know what to do. But yeah, I mean, I guess it's that premise of what is your other option? Right? There is no other option. Suzy [00:16:30]: That's right. There's no other option. Peter Shankman [00:16:32]: Add, it's interesting because we worry about I'm sitting here, I'm listening to you. I'm like, Jessa, Christ, it's 98ft underwater, and she loses a fin. And I'm thinking you can't stop to get it right. You just sort of have to let it go. And so, okay, do what you have to do. Right. And this is what you train for. Suzy [00:16:50]: That's right. Peter Shankman [00:16:51]: And again, there's no small talk. There's no, oh, what would you rather do? There's no oh, honey, I don't know. What do you want to eat tonight? No, it's get out. Yeah, right. So you make than work. No, it makes perfect sense. But Jessa, 98ft of door. It's it's so funny. The only thing that that really physically scares me to the point where I can't even watch it is these guys who do sunken wet cave diving where they wear the air and they go into these ridiculously tight. And there's always a story, like people who have died doing that. I'm watching them skirt through these caves that are like they have half an inch above them. They have to take off the air bottle and put it next. What is wrong with you people? Yeah, I'll go jump into a perfectly plane because I'm not going to get Stuck through the middle of the earth, Jessa. Peter Shankman [00:17:47]: But, yeah, I get the freedom. I totally get the freedom that you feel it. But again, Steven, free diving is more freedom because you're not stuck in between the middle of the earth. I don't know. Suzy [00:17:56]: That's right. Peter Shankman [00:17:57]: Anyway, I want to be respectful of your time. Suzy, this was amazing. What a great story. I really like to have you back, if at all possible. Next time I'm down under, next time in Australia, I'm coming to visit, no question about it. You can take me out of the water. Peter Shankman [00:18:09]: That would be awesome. Suzy [00:18:10]: Absolutely. Yeah. We've got some nice things. Peter Shankman [00:18:12]: Thank you so much for taking the time. I really, really appreciate it. Suzy [00:18:15]: Thank you, Peter. Keep up the good work. Peter Shankman [00:18:17]: Thank you, guys. As always. Faster Than Normal is intended for you and yours! Shoot me, email. Let me know you want to hear. Peter Petershankman.com. I'm at Peter Shankman everywhere but Twitter, because Twitter sucks. Now, Add, if you're on Blue Sky, you can find me there, too. Let us know what you want to hear faster than most for you. We'll see you guys next week. ADHD is a gift on a curse, and I'd rather here's my new quote. I would rather a child start therapy at an early age and learn that they're brilliant than spend the next 30 years undoing the belief that they're broken. We'll see you soon, guys. Stay safe.  — Credits: You've been listening to the Faster Than Normal podcast. We're available on iTunes, Stitcher and Google play and of course at www.FasterThanNormal.com I'm your host, Peter Shankman and you can find me at shankman.com and @petershankman on all of the socials. If you like what you've heard, why not head over to your favorite podcast platform of choice and leave us a review, come more people who leave positive reviews, the more the podcast has shown, and the more people we can help understand that ADHD is a gift, not a curse. Opening and closing themes were composed and produced by Steven Byrom who also produces this podcast, and the opening introduction was recorded by Bernie Wagenblast. Thank you so much for listening. We'll see you next week! 

Giant dinosaurs found in Australia migrated through Antarctica; A map of arctic industrial pollution shows where risks might arise as permafrost melts; A new technology is showing where baby sharks are born; Polynesian tool finds support the oral histories behind Moana; Incorporating diversity of human genomes in new Pangenome; Comparing 240 mammalian genomes helps illuminate what makes us human.

Did you know your omega-3 levels can be predictive of good health outcomes and cholesterol levels? An Omega-3 Index of 8% or higher is ideal, yet most people have a percentage of around 4-6%.    Today we're discussing why it's important to measure your omega-3 levels, and what you can do to optimize these levels. Plus, we'll answer the question: is there a relationship between fatty acids and longevity?   I'm joined by Dr. Bill Harris, PhD, FASN, President of the Fatty Acid Research Institute and Founder of OmegaQuant Analytics. We're diving into omega-6s and omega-3s and discussing the benefits of these fatty acids and where they come from. We also cover the importance of maintaining a ratio of omega-6 and omega-3, and whether or not omega-3s have an effect on blood clotting and blood circulation.   Dr. Harris has been a leading researcher in the omega-3 fatty acid field for over 40 years. He has more than 300 scientific papers on fatty acids and health, the vast majority on omega-3. He has been on the faculty of three medical schools (Universities of Kansas, Missouri (at Kansas City), and South Dakota), and has received 5 NIH grants to study omega-3. He was the co-author on three AHA statements on fatty acids and heart health. As the co-inventor of the Omega-3 Index (and other omega-3 blood tests) and founder of OmegaQuant Analytics, Dr. Harris has been ranked among the top 2% of scientists worldwide based on the impact of his research.    What we discuss: 00:02:38 - Omega-3s and their effects on blood clotting and blood circulation  00:07:23 - The value of omega-6 00:11:54 - The ratio of omega-6 and omega-3 00:18:03 - Where do arachidonic acid and linoleic acid come from, and what do they do? 00:21:32 - The signs and symptoms of omega-6 deficiency  00:25:22 - The components of omega-3s 00:31:04 - EPA and DHA   00:41:35 - Is there a relationship between omega-6 and omega-3 levels and longevity? 00:46:31 - Fish as a source of omega-3  00:57:21 - Mammalian sourced omega-3s 01:01:34 - What should people be looking out for in their supplements?  01:06:35 - 3 things to keep in mind about omega-3s and omega-6s    Key Takeaways: Looking at levels of omega-6 fatty acids in the blood can predict future diseases like heart disease and diabetes. Higher levels of linoleic acid in the blood are associated with lower risk for these diseases.  Increasing your levels of omega-3 is more important than worrying about getting your omega-6 levels down in order to have a good ratio between the two. It is also important to focus on EPA and DHA when it comes to types of omega-3s. It's important to measure your omega-3 levels. These levels are predictive of good health outcomes and even cholesterol levels. Oily fish like salmon and mackerel are great sources of omega-3s. Find more from Nathalie: YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ Facebook: https://www.facebook.com/groups/462749384302295 Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance Instagram: https://www.instagram.com/nathalieniddam/ Work with Nat: Book Your 20 MInute Optimization Consult: https://calendly.com/nniddam/intro-call?month=2021-08 Find more from Dr. Bill Harris: Website: www.omegaquant.com, www.fareinst.com  Facebook: https://www.facebook.com/Omega3Index Instagram: https://www.instagram.com/omega3index/?hl=en LinkedIn: https://www.linkedin.com/company/omegaquant-analytics/?viewAsMember=true Twitter: https://twitter.com/OmegaQuant YouTube: https://www.youtube.com/channel/UCZhRX5MX7-dFLXNZjsjhKKw About the Sponsors: Mitopure: Use code NAT10 for 10% off your order at https://www.mitopure.com/ LMNT: https://drinklmnt.com/ Berkeley Life: Use my code NIDDBL for 10% off at berkeleylife.com  

Could our brains make us less lonely? Sean Illing talks with psychiatrist and author Julie Holland, whose new book Good Chemistry takes on the crisis of disconnectedness we face today. They discuss the brain chemistry of attachment and human connection, how psychedelics can be used both in therapeutic contexts and to help us feel more connected to others, and the toll that this crisis of isolation can take on us — emotionally, physically, and spiritually. Host: Sean Illing (@seanilling), host, The Gray Area Guest: Julie Holland, MD (@BellevueDoc), psychiatrist; medical advisor to MAPS; author References:  Good Chemistry: The Science of Connection from Soul to Psychedelics by Julie Holland (Harper; 2022) "Work and the Loneliness Epidemic" by Vivek Murthy (Harvard Business Review; Sept. 26, 2017) "Loneliness in U.S. Subsides From Pandemic High" by Dan Witters (Gallup; Apr. 4) The Red Book by Carl Jung (written from 1914–1930; pub. Norton; 2009) "People would rather be electrically shocked than left alone with their thoughts" by Nadia Whitehead (Science; July 3, 2014) "Mammalian central nervous system trace amines" by Mark D. Berry (Journal of Neurochemistry; vol. 90 (2), July 2004) "The connection between oxytocin and autism, explained" by Peter Hess (Spectrum; Jan. 6, 2022) Moody Bitches by Julie Holland (Penguin; 2016) "Youth Suicide Risk Increased Over Past Decade" by Farzana Akkas (Pew; Mar. 3) "MAPS predicts FDA approval for MDMA-assisted therapy in 2024" by Brian Buntz (Drug Discovery & Development ; Jan. 27) "Psychedelics May Be Part of U.S. Medicine Sooner Than You Think" by Jamie Ducharme (TIME; Feb. 8) Alex & Allyson Grey "Can magic mushrooms unlock depression?" by Dr. Rosalind Watts (Medium; Feb. 28, 2022) How Psychedelics Can Help Save the World by Stephen Gray; foreword by Julie Holland (Park Street Books; 2022) Enjoyed this episode? Rate The Gray Area ⭐⭐⭐⭐⭐ and leave a review on Apple Podcasts. Subscribe for free. Be the first to hear the next episode of The Gray Area. Subscribe in your favorite podcast app. Support The Gray Area by making a financial contribution to Vox! bit.ly/givepodcasts This episode was made by:  Producer: Erikk Geannikis Engineer: Patrick Boyd Editorial Director, Vox Talk: A.M. Hall Learn more about your ad choices. Visit podcastchoices.com/adchoices

During labor, you want contractions that are longer, stronger, and closer together. But why? Dr. Sarah Buckley and Adriana take a deep dive into the amazing and fascinating hormonal dance that happens during the birthing process, and how interventions such as synthetic oxytocin or an epidural can lead to a cascade of interventions that negatively impact the process for both the birthing person and their baby. They also talk about ways to support the physiology of birth (regardless of what path it takes) in order to help fill any ‘hormonal gaps' that may occur.Get the most out of this episode by checking out the resources, transcript, and links listed on its show notes page.  If you liked this episode, listen to our interview on Your Baby, The Mammal, and our episode on Epidurals and breastfeeding.You can connect with Sarah on Facebook at drsarahbuckley. You can connect with us on Instagram at @BirthfulPodcast and email us at podcast@Birthful.com. If you enjoy what you hear, download Birthful's Postpartum Plan FREE when you sign up for our weekly newsletter! You can also sign-up for Adriana's Own Your Birth online BIRTH preparation classes and her Thrive with Your Newborn online POSTPARTUM preparation course.Follow us on Goodpods, Apple Podcasts, Amazon Music, Spotify, and anywhere you listen to podcasts.Our Sponsors:* Visit HomeThreads.com/BIRTHFUL today and get a 15% off code for your first order!Support this podcast at — https://redcircle.com/birthful/donationsAdvertising Inquiries: https://redcircle.com/brands