Podcasts about Downstream

Thu, 08 Jan 2026 22:45:00 GMT http://relay.fm/downstream/110 http://relay.fm/downstream/110 Jason Snell Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. clean 4305 Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Casey Liss Links and Show Notes: Our Picks: Jason: Down Cemetery Road (Apple TV), The Pitt (HBO Max) Casey: Shoresy (Hulu) Get Downstream+ and don't miss a segment! Submit Feedback Channels — TV Everywhere Is cablecard sup

For over 4,000 years, silkworms have connected civilizations through ancient trade routes. Now, KAICO Ltd., a Japanese biotech spin-off from Kyushu University, is transforming these creatures into living bioreactors capable of producing complex recombinant proteins and vaccine antigens—without the bioreactors, expensive media, or massive water consumption of conventional platforms.Masafumi Osawa, Business Development Lead at KAICO, brings an unconventional path to biotech. Trained in cultural anthropology with fieldwork experience in Indonesia, he witnessed firsthand the healthcare disparities that drive his current mission. After years in pharmaceutical business development at Towa Pharmaceutical, he joined KAICO to help scale a technology he believes could reshape global vaccine accessibility. His cross-cultural expertise now proves invaluable as KAICO expands internationally, with active partnerships in Vietnam and Thailand and growing interest from other regions.Episode highlights:Masafumi's transition from anthropology to biotech, and how cross-cultural expertise benefits global health collaborations. (04:15)The founding story of KAICO, spun out from Kyushu University and focused on recombinant proteins and vaccine antigen production (08:45)Step-by-step overview of the silkworm baculovirus expression system, including pupae handling and bioprocessing basics. (10:28)Practical differences between silkworms, E. coli, mammalian, and insect cell culture platforms—exploring advantages and drawbacks. (13:10)Strategies KAICO uses to control silkworm variability, including SPF grade sourcing, diet, environment, and documentation for pharmaceutical acceptance. (15:08)Production scalability: a single pupa can match 100–1000 ml of insect cell culture, with major implications for cost and environmental footprint. (16:42)Downstream harvesting and purification—how KAICO extracts and processes proteins from silkworm pupae, keeping methods largely familiar to traditional systems. (19:31)Regulatory and GMP challenges of using live organisms, and KAICO's approach to satisfying authorities and ensuring product consistency. (21:43)Whether you're curious about alternative biomanufacturing methods or want a transparent look at silkworm-based protein expression from research to the clinic, this episode delivers practical insights and thoughtful discussion.Connect with Masafumi Osawa:LinkedIn: www.linkedin.com/in/masa-osawaKAICO Ltd.: www.kaicoltd.jp/enNext step:Need fast CMC guidance? → Get rapid CMC decision support hereOne bad CDMO decision can cost you two years and your Series A. If you're navigating tech transfer, CDMO selection, or IND prep, let's talk before it gets expensive. Two slots open this month.Support the show

After ‘Operation Al-Aqsa Flood' on October 7th, a specific narrative quickly emerged and pervaded the entire Western mainstream media. Namely, that unprecedented horrors were committed against the state of Israel and that whatever way it responded was justified. Any deviation from this narrative was quickly shut down. In the intervening years, the British state has […]

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the benefit of shunts in idiopathic normal-pressure hydrocephalus, how neurologists drive downstream revenue, and anticoagulant monotherapy after stroke.

Ash Sarkar and Aaron Bastani joined each other on 17th December for a special end-of-year Downstream, wrapping up the year in politics.

Norman Finkelstein is one of the west's leading anti-Zionist scholars. The son of Holocaust survivors, he has spent his life studying and critiquing Israel's assault on Palestine, decades before it became socially acceptable to do so. Yet despite having dedicated his career to it, by the day before Hamas' attack in October 2023, Norman had […]

Thu, 18 Dec 2025 00:15:00 GMT http://relay.fm/downstream/109 http://relay.fm/downstream/109 Jason Snell Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. clean 3871 Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. Guest Starring: Tim Goodman Links and Show Notes: Shows mentioned: Black Summer (Netflix), Severance (Apple TV), The Studio (Apple TV), Families Like Ours (Denmark; Netflix), Pluribus (Apple TV), The Diplomat (Netflix), The Bear (Hulu), Asura (Japan; Netflix), The American Revolution (PBS), Slow Horses (Apple TV), Adolescence (Netflix), Department Q (Netflix), Ludwig (BBC/Britbox), Nine Puzzles (Korea; Hulu), Deli Boys (Hulu), The Trunk (Korea; Netflix), Karma (Korea; Netflix), Trigger (Korea; Netflix), My Name (Korea; Netflix), Extracurricular (Korea; Netflix). Get Downstream+ and don't miss a segment! Submit Feedback Downstream #85: A Holiday Visit from Tim Goodman - Relay Stream Inte

[Cross-posted from Downstream #109 on Relay FM.] Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, “Pluribus,” and his top shows of the year. Tim Goodman and Jason Snell.

Since Hamas launched its assault on October 7th, 2023, the group has become synonymous with evil in large parts of the Western media. Condemnation has come at the expense of critical engagement with the group's actions, objectives, and history, leaving a vacuum that has been filled with racist assumptions and conspiracy theories. Tareq Baconi is […]

Fri, 12 Dec 2025 00:00:00 GMT http://relay.fm/downstream/108 http://relay.fm/downstream/108 Jason Snell Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) clean 1693 Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: Get Downstream+ and don't miss a segment! Submit Feedback Disney Agrees to Bring Its Characters to OpenAI's Sora Videos - The New York Times Bob Iger's L

Fri, 12 Dec 2025 00:00:00 GMT http://relay.fm/downstream/108 http://relay.fm/downstream/108 Darth Vader Versus Ariel 108 Jason Snell Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) clean 1693 Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: Get Downstream+ and don't miss a segment! Submit Feedback Disney Agrees to Bring Its Characters to OpenAI's Sora Videos - The New York Times Bob Iger's Latest Legac

Did you know that the standard of Google searches has actually gotten worse over recent years? Once you think about it, it makes sense. Highly effective search means fewer searches overall. And fewer searches means less ad revenue. The financial basis of Alphabet, which is Google's parent company, is, of course, digital advertising. Which means […]

Elaine Low, Natalie Jarvey, Sean McNulty and Lesley Goldberg all gathered Friday morning for a special live episode of Ankler Agenda to break down the repercussions of potentially the most significant piece of show business news this decade: Netflix's acquisition of Warner Bros. Top-line concerns include: The thousands of lost jobs that will worsen unemployment in the industry — already at Depression-era levels Whether movie theaters can survive the “consumer-friendly” windows Netflix co-CEO Ted Sarandos referenced in a Friday call with investors Netflix's potential new arsenal: all-star showrunners (J.J. Abrams, Greg Berlanti and Chuck Lorre, to name a few) and a gaming vertical at last Downstream effects on linear syndication The future of the peerless brand HBO “Everybody is just shell-shocked,” Elaine said of the calls and texts she fielded all day. “The main reaction that I've been getting is that people are scared. People are nervous.” Learn more about your ad choices. Visit megaphone.fm/adchoices

Small homeschooling lessons today become major downstream results tomorrow. This episode encourages you to trust the long game. Show notes are at https://www.4onemore.com/337

Steve and Charlie listened to LSU AD Verge Ausberry's media availability following Lane Kiffin's introductory press conference.

Whether you love or loathe his tactics, it's hard to deny the disruptive impact that Roger Hallam has had on British politics via the activist organisations he has led, Extinction Rebellion and Just Stop Oil. He joins Ash Sarkar fresh from his latest stint in prison, where he wrote a treatise for Your Party that […]

Support for the Green party in Britain has been steadily rising for the past few decades. However, few predicted that when Zack Polanski took office as Green party leader in September, membership would surge from 70,000 to 150,000 members in a matter of months. According to the latest polling, the party's share of the vote […]

Thu, 20 Nov 2025 17:00:00 GMT http://relay.fm/downstream/107 http://relay.fm/downstream/107 Jason Snell Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. clean 3559 Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Alan Sepinwall Links and Show Notes: Good TV shows mentioned: The Pitt, Ludwig, Severance, Adolescence at the top, then: Pluribus, Slow Horses, Andor, The Studio, Hacks, The Diplomat, The Lowdown, It's Always Sunny in Philadelphia Get Downstream+ and don't miss a segment! Submit Feedback What's Alan Watching? Review: 'Blue Lights' isn't the Belfast equivalent of 'The Wire.' And that's okay. Why 'Brockmire' Was This Year's Best, Filthiest Comedy Surprise Series finale review: 'How I Met Your Mother' - 'Last Forever': How they conned us all Links to Sepinwall's episode-by-episode reviews for every show in his book, The Revolution Was Televised

Thu, 20 Nov 2025 17:00:00 GMT http://relay.fm/downstream/107 http://relay.fm/downstream/107 A Thanksgiving Visit from Alan Sepinwall 107 Jason Snell Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. clean 3559 Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Alan Sepinwall Links and Show Notes: Good TV shows mentioned: The Pitt, Ludwig, Severance, Adolescence at the top, then: Pluribus, Slow Horses, Andor, The Studio, Hacks, The Diplomat, The Lowdown, It's Always Sunny in Philadelphia Get Downstream+ and don't miss a segment! Submit Feedback What's Alan Watching? Review: 'Blue Lights' isn't the Belfast equivalent of 'The Wire.' And that's okay. Why 'Brockmire' Was This Year's Best, Filthiest Comedy Surprise Series finale review: 'How I Met Your Mother' - 'Last Forever': How they conned us all Links to Sepinwall's episode-by-episode reviews for every show in his book, The Revolution Was Televised

At Novara, we focus on the trends that are remaking the world and affecting our lives: technological development and automation, multipolarity, the demise of an American-led world order and the rise of China. On Downstream this week is a man whose work draws together all of these themes: former World Bank macroeconomist and leading expert […]

Investigative journalist Paul Holden has spent the last four years digging into the political machinations that brought Keir Starmer's Labour Party into office – findings that propel his powerful 2025 book, The Fraud: Keir Starmer, Labour Together and the Crisis of British Democracy. He tells Ash Sarkar about the cache of leaked emails that revealed the […]

 Dr. Francisco Javier Bonilla is a historian of Latin America specializing in environmental history, infrastructure, and urban development. His research focuses on Panama and the wider Caribbean, examining how water, cities, and U.S. empire have shaped everyday life across the region. He received his PhD in History from Carnegie Mellon University and is currently turning his dissertation, Downstream from the Locks: The Technopolitics of Water in Panama's Urban Borderlands, into a book.    If the US wanted to seize the Panama Canal, it would be illegal due to its status of neutrality.  Much like the USA, Panama has a burgeoning inequality that breaks along racial and social lines.   Wealthy elites and corporations are purchasing media outlets.    Due to pressure of the US and Corporate Media a vigorous discussion seldom occurs re: the future of the Canal and extra-judicial bombings off the coast of Venezuela, with little or no proof of guilt.  

This one goes to eleven… NO this one goes to 31! Levi's all-in on expanding our musical pallate. We talked about what colors and emotions are available in microtonality, how to get into the wild world, and the frontiers of music theory. Sometimes it feels like everything in music has been “figured out.” Levi's here to tell us that couldn't be further from the truth!For 30% off your first year of DistroKid to share your music with the world click ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DistroKid.com/vip/lovemusicmore⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe to this pod's blog on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Substack⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to receive deeper dives on the regular

In 1989, Francis Fukuyama, then a very young political scientist, declared that history was over. He wrote a book with the same title just a couple of years later. The Cold War had finished, the USSR had collapsed, liberal democracy and market capitalism reigned supreme, and it wasn't going to change. And yet in the […]

Fri, 31 Oct 2025 23:30:00 GMT http://relay.fm/downstream/106 http://relay.fm/downstream/106 Jason Snell Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) clean 2052 Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) This episode of Downstream is sponsored by: Claude: Get 50% off Claude Pro, including access to Claude Code. Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: Pluribus (Apple TV) Jason: Seth Meyers Corrections (YouTube) Get Downstream+ and don't miss a segment! Submit Feedback David Ellison's Paramount Doesn't Need Taylor Sheridan Netflix

Fri, 31 Oct 2025 23:30:00 GMT http://relay.fm/downstream/106 http://relay.fm/downstream/106 Strike While My Leverage Is Hot 106 Jason Snell Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) clean 2052 Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) This episode of Downstream is sponsored by: Claude: Get 50% off Claude Pro, including access to Claude Code. Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: Pluribus (Apple TV) Jason: Seth Meyers Corrections (YouTube) Get Downstream+ and don't miss a segment! Submit Feedback David Ellison's Paramount Doesn't Need Taylor Sheridan Netflix taps bank

In this Halloween-themed episode, Veronica Breckenridge from First Bite returns to discuss her eye-opening "Industrial Bio-Manufacturing Graveyard Report." Drawing from her experience scaling companies like Apple and Tesla, Veronica reveals why 80% of bio-manufacturing startups fail—and it's not because of bad science. The conversation explores critical mistakes like targeting commodity markets too early, underestimating downstream processing costs, and the "build it and they will come" mentality that has buried promising ventures. Veronica explains why now is actually the best time to invest in bio-manufacturing, citing decreasing costs (3 million times cheaper in 25 years), rising consumer demand for healthier alternatives to petroleum-based products, and increased government support for domestic manufacturing. She shares tactical advice on patient capital structures, the importance of strategic partnerships over going solo, and why bio-manufacturing is more analogous to hardware scaling than pharmaceutical development. The episode offers valuable lessons for founders, investors, and anyone interested in the future of sustainable manufacturing.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:(00:00:00) - Halloween intro and SNL's Snack Homies discussion(00:04:17) - Zombie apocalypse: Could fungi or viruses cause real zombies?(00:09:12) - Beyond Meat stock surge and meme trading(00:11:34) - Introducing the Graveyard Report and Veronica Breckenridge(00:14:23) - Why Veronica moved from Tesla to bio-manufacturing(00:19:45) - The three recurring market fit errors killing startups(00:27:56) - Why targeting commodity markets is a seductive trap(00:35:18) - Downstream processing: The overlooked cost killer(00:42:31) - CapEx overruns and the importance of strategic partnerships(00:48:07) - Patient capital structures for deep tech ventures(00:53:22) - What makes this moment different: Why invest now(00:58:14) - Quick fire questions and closing thoughtsLinks and Resources:First BightThe Industrial Biomanufacturing Graveyard ReportBiowell Biotech AcceleratorGinkgo ConsultingCapgeminiMcKinsey120. Busting Biotech's Bottlenecks: Veronica Breckenridge on the Path to Industrial Scale151. Report on Reports: Cash Flow, Carbon, and the BioeconomyZombie-like effects from fungusBeyond Meat's Stock SpikeTedX BostonTechnoeconomic Analysis Tool⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Topics Covered: industrial biomanufacturing, biotech, business, growth stage, graveyard report, halloweenHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media

Iran has been in the news a lot in 2025. Over recent decades, it has been a variable in Iraq, Afghanistan, Syria, Lebanon, Israel, and Palestine. But during the Twelve Day War with Israel in June of this year, Iran very much took centre stage. People started asking questions, chief among them being: What does […]

The Gaza Strip, home to 2.2 million people, is a tiny land mass about the same size as the Isle of Wight. Yet in terms of munitions by weight, Gaza has been subjected to more than all of the bombs dropped on Dresden, Hamburg, and London combined, over the whole of World War II. Another […]

Just over two years after the beginning of the genocide in Gaza, and just days after the announcement of a ceasefire, Aaron Bastani spoke to three Palestinian writers in front of a live audience at EartH in Hackney. Ahmed Alnaouq is the host of Palestine Deep Dive and the co-founder of ‘We Are Not Numbers', […]

Thu, 16 Oct 2025 23:45:00 GMT http://relay.fm/downstream/105 http://relay.fm/downstream/105 Jason Snell Hulu goes worldwide, Apple drops the plus and explores a relationship with Formula 1, the Lakers get immersive, the NBA is everywhere all at once, and our TV Picks. Hulu goes worldwide, Apple drops the plus and explores a relationship with Formula 1, the Lakers get immersive, the NBA is everywhere all at once, and our TV Picks. clean 3468 Hulu goes worldwide, Apple drops the plus and explores a relationship with Formula 1, the Lakers get immersive, the NBA is everywhere all at once, and our TV Picks. This episode of Downstream is sponsored by: Claude: Get 50% off Claude Pro, including access to Claude Code. Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Will Carroll Links and Show Notes: TV Picks: Will: Passenger Princess (YouTube) Jason: Travel Man with Richard Ayoade (YouTube) Get Downstream+ and don't miss a segment! Submit Feedback Hulu Becomes Global General Entertainment Brand on Disney+ on Oct. 8 | The Walt Disney Company Disney has big plans for Hulu - Fast Company Apple and NBCUniversal introduce the Apple TV and Peacock Bundle - Apple Apple wants “to own a sport end to end” – Six Colors Immersive live NBA games coming to Vision Pro – Six Colors NBA on X: "2025-26 NBA Season Watch Guide ✍️ The 2025-26 regular season begins Tuesday, October 21 on

Thu, 16 Oct 2025 23:45:00 GMT http://relay.fm/downstream/105 http://relay.fm/downstream/105 Another Piece of Red Yarn 105 Jason Snell Hulu goes worldwide, Apple drops the plus and explores a relationship with Formula 1, the Lakers get immersive, the NBA is everywhere all at once, and our TV Picks. Hulu goes worldwide, Apple drops the plus and explores a relationship with Formula 1, the Lakers get immersive, the NBA is everywhere all at once, and our TV Picks. clean 3468 Hulu goes worldwide, Apple drops the plus and explores a relationship with Formula 1, the Lakers get immersive, the NBA is everywhere all at once, and our TV Picks. This episode of Downstream is sponsored by: Claude: Get 50% off Claude Pro, including access to Claude Code. Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Will Carroll Links and Show Notes: TV Picks: Will: Passenger Princess (YouTube) Jason: Travel Man with Richard Ayoade (YouTube) Get Downstream+ and don't miss a segment! Submit Feedback Hulu Becomes Global General Entertainment Brand on Disney+ on Oct. 8 | The Walt Disney Company Disney has big plans for Hulu - Fast Company Apple and NBCUniversal introduce the Apple TV and Peacock Bundle - Apple Apple wants “to own a sport end to end” – Six Colors Immersive live NBA games coming to Vision Pro – Six Colors NBA on X: "2025-26 NBA Season Watch Guide ✍️ The 2025-26 regular season begins Tuesday, October 21 on NBC and Pea

Renee Troughton: Managing Dependencies and Downstream Bottlenecks in Scrum Read the full Show Notes and search through the world's largest audio library on Agile and Scrum directly on the Scrum Master Toolbox Podcast website: http://bit.ly/SMTP_ShowNotes. "For the actual product teams, it's not a problem for them... It's more the downstream teams that aren't the product teams, that are still dependencies... They just don't see that work until, hey, we urgently need this." Renee brings a dual-edged challenge from her current work with dozens of teams across multiple business lines. While quarterly planning happens at a high level, small downstream teams—middleware, AI, data, and even non-technical teams like legal—are not considered in the planning process. These teams experience unexpected work floods with dramatic peaks and troughs throughout the quarter. The product teams are comfortable with ambiguity and incremental delivery, but downstream service teams don't see work coming until it arrives urgently. Through a coaching conversation, Renee and Vasco explore multiple experimental approaches: top-to-bottom stack ranking of initiatives, holding excess capacity based on historical patterns, shared code ownership where downstream teams advise rather than execute changes, and using Theory of Constraints to manage flow into bottleneck teams. They discuss how lack of discovery work compounds the problem, as teams "just start working" without identifying all players who need involvement. The solution requires balancing multiple strategies while maintaining an experimentation mindset, recognizing that complex systems require sensing our way toward solutions rather than predicting them. Self-reflection Question: Are you actively managing the flow of work to prevent downstream bottlenecks, or are you allowing your "downstream teams" to be repeatedly overwhelmed by last-minute urgent requests? [The Scrum Master Toolbox Podcast Recommends]

In this month's episode of the Oil & Gas Measurement Podcast, host Weldon Wright is joined by Stan Calame to discuss upstream measurement trends in oil and gas.  Visit PipelinePodcastNetwork.com for a full episode transcript, as well as detailed show notes with relevant links and insider term definitions.

Artificial intelligence is set to be one of the most disruptive technologies this century. For some, a machine capable of augmenting its own intelligence is a matter of time — and could even arrive within a decade. This week's guest is philosopher and author William MacAskill. One of the leading thinkers in the Effective Altruism […]

Economist, and former finance minister of Greece, Yanis Varoufakis joins Aaron to discuss his most recent book Raise Your Soul: A Personal History of Resistance, a memoir about the women in Yanis' family who raised him, and gave him his political conscience. They discuss the Hegelian Master-Slave dialectic, is patriarchy harmful to the perpetrators, as […]

Fri, 03 Oct 2025 16:15:00 GMT http://relay.fm/downstream/104 http://relay.fm/downstream/104 Jason Snell We dive into the aftermath of the Jimmy Kimmel affair and the strange balance between TV networks and local affiliates. [Downstream+ subscribers also get: Streaming price hikes, Prime Video's future, and David Letterman's streaming strategy.] We dive into the aftermath of the Jimmy Kimmel affair and the strange balance between TV networks and local affiliates. [Downstream+ subscribers also get: Streaming price hikes, Prime Video's future, and David Letterman's streaming strategy.] clean 2704 We dive into the aftermath of the Jimmy Kimmel affair and the strange balance between TV networks and local affiliates. [Downstream+ subscribers also get: Streaming price hikes, Prime Video's future, and David Letterman's streaming strategy.] Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: The Marlow Murder Club (PBS), High Potential (ABC) Jason: The Lowdown (FX/Hulu), Alien: Earth (FX/Hulu) Get Downstream+ and don't miss a segment! Submit Feedback Bob Iger's Jimmy Kimmel Choice: Money or the 1st Amendment? What Is Disney Thinking? The Kimmel Saga and

Fri, 03 Oct 2025 16:15:00 GMT http://relay.fm/downstream/104 http://relay.fm/downstream/104 Like a Vaccination 104 Jason Snell We dive into the aftermath of the Jimmy Kimmel affair and the strange balance between TV networks and local affiliates. [Downstream+ subscribers also get: Streaming price hikes, Prime Video's future, and David Letterman's streaming strategy.] We dive into the aftermath of the Jimmy Kimmel affair and the strange balance between TV networks and local affiliates. [Downstream+ subscribers also get: Streaming price hikes, Prime Video's future, and David Letterman's streaming strategy.] clean 2704 We dive into the aftermath of the Jimmy Kimmel affair and the strange balance between TV networks and local affiliates. [Downstream+ subscribers also get: Streaming price hikes, Prime Video's future, and David Letterman's streaming strategy.] Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: The Marlow Murder Club (PBS), High Potential (ABC) Jason: The Lowdown (FX/Hulu), Alien: Earth (FX/Hulu) Get Downstream+ and don't miss a segment! Submit Feedback Bob Iger's Jimmy Kimmel Choice: Money or the 1st Amendment? What Is Disney Thinking? The Kimmel Saga and the Trouble

Blake and David examine the growing threat of AI-generated fake receipts, with 32% of accountants unable to recognize fraudulent documents and 30% reporting an increase in fraud since last year. They also discuss the concerning decline in entry-level auditor positions (down 43% since January) as firms adopt AI automation, while nearly half of accounts payable professionals now fear layoffs and also explore the concept of "work slop"—low-quality AI-generated work costing businesses nearly $200 per employee monthly—and debate whether firms should require clients to use standardized technology stacks, with only 37% currently doing so. SponsorsCloud Accountant Staffing - http://accountingpodcast.promo/cas Rippling - http://accountingpodcast.promo/ripplingBill.com - http://accountingpodcast.promo/bill.comBluebook - http://accountingpodcast.promo/bluebookChapters(01:43) - Headline Story: Tech Stack Adoption in Accounting Firms (03:05) - Survey Insights: Tech Stack Usage in Firms (07:15) - AI's Impact on Entry-Level Jobs (13:55) - The Rise of 'Work Slop' and Its Costs (20:44) - AI and Automation in Accounting (25:08) - Human-in-the-Loop Automation with Zapier (28:22) - AI in Tax Research and IT Blockers (30:51) - Competitive Moats and Custom Bots (32:26) - Exciting Changes in CPE Standards (34:59) - Drake Software's Cloud-Based Tax Solution (43:06) - State Department Embezzlement Scandal (44:59) - Trump's Tariff Announcements (50:28) - H-1B Visa Fee Increase (56:20) - Conclusion and CPE Information  Show Notes32% of accountants can't recognize AI-generated fake receipts https://www.accountingtoday.com/news/32-admit-they-cannot-recognize-ai-generated-fake-receiptsEntry-level auditor job postings fell 43%, per Randstad https://www.accountingtoday.com/news/entry-level-auditor-job-postings-fell-43-per-randstadAI-Generated "Workslop" Is Destroying Productivity https://hbr.org/2025/09/ai-generated-workslop-is-destroying-productivity97% say CPA firms not using tech efficiently says survey https://www.accountingtoday.com/news/97-say-cpa-firms-not-using-tech-efficiently-says-surveyCPA.com & BILL Growth Survey: How Firms Plan to Stay Ahead https://www.bill.com/blog/cpa-and-bill-growth-technology-surveyAP Pros Face Growing Layoff Concerns and See Automation as a Career Lifeline https://www.cpapracticeadvisor.com/2025/09/11/ap-pros-face-growing-layoff-concerns-and-see-automation-as-a-career-lifeline-2/168818/Get more control over your workflows with Human in the Loop! https://help.zapier.com/hc/en-us/articles/38838619533069-Get-more-control-over-your-workflows-with-Human-in-the-Loop54% use AI in tax research, but search engines remain prominent https://www.accountingtoday.com/news/54-use-ai-in-tax-research-but-search-engines-remain-prominentDrake Software Introduces Drake Tax Online https://www.cpapracticeadvisor.com/2025/09/24/drake-software-introduces-drake-tax-online/169572/Drake Software Launches Drake Tax Online: Powerful, Flexible Tax Software in the Cloud https://www.prnewswire.com/news-releases/drake-software-launches-drake-tax-online-powerful-flexible-tax-software-in-the-cloud-302566087.htmlNASBA, AICPA release proposed revisions to CPE standards https://www.journalofaccountancy.com/news/2025/sep/nasba-aicpa-release-proposed-revisions-to-cpe-standardsNASBA, AICPA Release Exposure Draft of Proposed Revisions to CPE Standardshttps://nasba.org/blog/2025/09/15/revisions-to-cpe-standards-2025/ H-1B FAQhttps://www.uscis.gov/newsroom/alerts/h-1b-faq Need CPE?Get CPE for listening to podcasts with Earmark: https://earmarkcpe.comSubscribe to the Earmark Podcast: https://podcast.earmarkcpe.comGet in TouchThanks for listening and the great reviews! We appreciate you! Follow and tweet @BlakeTOliver and @DavidLeary. Find us on Facebook and Instagram. If you like what you hear, please do us a favor and write a review on Apple Podcasts or Podchaser. Call us and leave a voicemail; maybe we'll play it on the show. DIAL (202) 695-1040.SponsorshipsAre you interested in sponsoring The Accounting Podcast? For details, read the prospectus.Need Accounting Conference Info? Check out our new website - accountingconferences.comLimited edition shirts, stickers, and other necessitiesTeePublic Store: http://cloudacctpod.link/merchSubscribeApple Podcasts: http://cloudacctpod.link/ApplePodcastsYouTube: https://www.youtube.com/@TheAccountingPodcastSpotify: http://cloudacctpod.link/SpotifyPodchaser:

In this episode, Paul learns what it's like to work at an energy company with Justin Valencia and Brittany Williams, both of whom work for the Chevron Corporation at their refinery in El Segundo, CA. Justin has a background in mechanical engineering, and is the Technology & Innovation Manager for Downstream, Midstream, and Chemicals. Brittany has a background in chemical engineering, and is a Short Range Process Engineer. During the interview, Justin and Brittany describe what their day-to-day work is like at a refinery. They discuss the various activities engineers are engaged in at the refinery and throughout Chevron's many other operations. And finally, Justin and Brittany discuss how engineering students can better prepare themselves for a career at an energy company like Chevron. Chevron Corporation website: www.chevron.com  Chevron Corporation YouTube channel: www.youtube.com/chevron    Have comments about this episode? Send your feedback to TESEpodcast@gmail.com and Paul will personally read your email. Episode produced and edited by Paul Nissenson. Recorded on August 21, 2025 at the Chevron refinery in El Segundo, CA.

In the summer of 2024, hotels sheltering Muslim asylum seekers across Britain were attacked by violent mobs. A year later, as the summer of 2025 drew to a close, a far-right demonstration of 100,000 people marched through London, bearing St George's flags and led by Tommy Robinson. On Downstream this week is Myriam François, a […]

Today's Todd Huff Show is hosted by former Indiana State Senator John Crane, who reflects on his journey in politics and why he chose to voluntarily term-limit himself. Drawing from nearly a decade in public office, Crane explains why politics is always downstream from culture—and why the real battle lies upstream in the war of worldviews.Crane shares candid insights from his time in the Indiana Senate, including his conviction that Christians are called to be a catalyst for redemptive good in politics. He challenges the Church to stop treating politics as “too dirty” for engagement and instead equip the next generation of biblically grounded leaders to step boldly into the arena.Drawing on Romans 12 and his personal prayer life while serving in office, Crane emphasizes that leadership is intentional influence—and every believer is called to shine light where darkness seems strongest. He urges the Church to take political discipleship seriously, raising up leaders who are thoughtful, principled, and courageous.If politics is downstream, the Church must go upstream to shape culture with truth, conviction, and biblical clarity. As Crane makes clear: the mission field of politics desperately needs faithful leaders.Freedom Marketplace: https://freedommarketplace.net The Stack: https://www.toddhuffshow.com/stack-of-stuff Email: todd@toddhuffshow.comPhone: 317.210.2830Follow us on…Instagram: @toddhuffshowFacebook: The Todd Huff ShowTwitter: @toddhuffshowLinkedIn: The Todd Huff ShowTikTok: @toddhuffshowSupport Our Partners:https://www.toddhuffshow.com/partners Show Sponsors: https://www.mypillow.com/todd Promo Code: TODD Red, White, & Brand – Text TODD at 317-210-2830 for a 10% discount.SolTea – Heart health made simple. Two softgels a day. Promo code TODD saves 50% + free shipping.Full Suite Wealth – Build a legacy that lasts. Advanced strategies + legal guidance. Start at FullSuiteWealth.com.4:8 Financial – Purpose-centered planning & Biblically Responsible Investing. See how your portfolio aligns with your values. Visit 48Financial.com/Todd. 

Today's Todd Huff Show is hosted by former Indiana State Senator John Crane, who reflects on his journey in politics and why he chose to voluntarily term-limit himself. Drawing from nearly a decade in public office, Crane explains why politics is always downstream from culture—and why the real battle lies upstream in the war of worldviews.Crane shares candid insights from his time in the Indiana Senate, including his conviction that Christians are called to be a catalyst for redemptive good in politics. He challenges the Church to stop treating politics as “too dirty” for engagement and instead equip the next generation of biblically grounded leaders to step boldly into the arena.Drawing on Romans 12 and his personal prayer life while serving in office, Crane emphasizes that leadership is intentional influence—and every believer is called to shine light where darkness seems strongest. He urges the Church to take political discipleship seriously, raising up leaders who are thoughtful, principled, and courageous.If politics is downstream, the Church must go upstream to shape culture with truth, conviction, and biblical clarity. As Crane makes clear: the mission field of politics desperately needs faithful leaders.Freedom Marketplace: https://freedommarketplace.net The Stack: https://www.toddhuffshow.com/stack-of-stuff Email: todd@toddhuffshow.comPhone: 317.210.2830Follow us on…Instagram: @toddhuffshowFacebook: The Todd Huff ShowTwitter: @toddhuffshowLinkedIn: The Todd Huff ShowTikTok: @toddhuffshowSupport Our Partners:https://www.toddhuffshow.com/partners Show Sponsors: https://www.mypillow.com/todd Promo Code: TODD Red, White, & Brand – Text TODD at 317-210-2830 for a 10% discount.SolTea – Heart health made simple. Two softgels a day. Promo code TODD saves 50% + free shipping.Full Suite Wealth – Build a legacy that lasts. Advanced strategies + legal guidance. Start at FullSuiteWealth.com.4:8 Financial – Purpose-centered planning & Biblically Responsible Investing. See how your portfolio aligns with your values. Visit 48Financial.com/Todd. 

It's almost 10 years since Britain voted to leave the EU, and we're still dealing with the consequences. In his new book, Between The Waves, Politico's chief UK political correspondent Tom McTague argues that the journey to Brexit really began with Enoch Powell, before be taken up by his political heir, Nigel Farage. He talks […]

Thu, 18 Sep 2025 01:00:00 GMT http://relay.fm/downstream/103 http://relay.fm/downstream/103 Jason Snell The possibility of David Ellison buying Warner Bros. Discovery to add to his collection, the threat and promise of spread-out sports rights, sponsorships that might become forbidden fruit, Netflix live boxing success, TV picks, and your letters! The possibility of David Ellison buying Warner Bros. Discovery to add to his collection, the threat and promise of spread-out sports rights, sponsorships that might become forbidden fruit, Netflix live boxing success, TV picks, and your letters! clean 4632 The possibility of David Ellison buying Warner Bros. Discovery to add to his collection, the threat and promise of spread-out sports rights, sponsorships that might become forbidden fruit, Netflix live boxing success, TV picks, and your letters! This episode of Downstream is sponsored by: Claude: Get 50% off Claude Pro, including access to Claude Code. Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Will Carroll Links and Show Notes: TV Picks: Will: The Breakthrough (Netflix) Jason: Emmy winners Somebody Somewhere and The Pitt (HBO Max) Get Downstream+ and don't miss a segment! Submit Feedback

Thu, 18 Sep 2025 01:00:00 GMT http://relay.fm/downstream/103 http://relay.fm/downstream/103 Apologies to Yugoslavia 103 Jason Snell The possibility of David Ellison buying Warner Bros. Discovery to add to his collection, the threat and promise of spread-out sports rights, sponsorships that might become forbidden fruit, Netflix live boxing success, TV picks, and your letters! The possibility of David Ellison buying Warner Bros. Discovery to add to his collection, the threat and promise of spread-out sports rights, sponsorships that might become forbidden fruit, Netflix live boxing success, TV picks, and your letters! clean 4632 The possibility of David Ellison buying Warner Bros. Discovery to add to his collection, the threat and promise of spread-out sports rights, sponsorships that might become forbidden fruit, Netflix live boxing success, TV picks, and your letters! This episode of Downstream is sponsored by: Claude: Get 50% off Claude Pro, including access to Claude Code. Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Will Carroll Links and Show Notes: TV Picks: Will: The Breakthrough (Netflix) Jason: Emmy winners Somebody Somewhere and The Pitt (HBO Max) Get Downstream+ and don't miss a segment! Submit Feedback

What were the ancient alternatives to democracy? Did people in the Bronze Age forget how to write – or deliberately stop? And what's the use in studying ancient languages? In a Downstream IRL recorded at EartH Hackney, Aaron Bastani speaks to Josephine Quinn, Professor of Ancient History at Cambridge University, about some lesser-known aspects of the […]

Alderman highlights the rapid expansion of information exposure over the past 50 years, leading to an "algorithmic undertow" that channels individuals into echo chambers. Here we explore how to become digitally mature and mindfully intentional in our engagement with the increasingly fragmented social landscape. Bruce Alderman, MA, is an affiliate faculty professor at John F. Kennedy University in the Consciousness and Transformative Studies and Holistic Counseling Psychology departments. He is the Associate Director of the Blue Sky Leaders Certificate Program at the California Institute of Integral Studies His essays and white papers have been published in many prestigious publications and anthologies on consciousness studies, and he is co-creator, producer, and occasional host of the YouTube series The Integral Stage.Interview Date: 6/13/2025 Tags: Bruce Alderman, Penn Gillette, algorithmic undertow, echo chambers, information bubbles, Roy Bhaskar, demi realities, critical realism, digital realities, Bohemian dialog, David Bohm, Jainism, Anekāntavāda, non one-sidedness, non one-pointedness. critical realism, integral theory, Ken Wilber, integral theory, Personal Transformation, Philosophy, Psychology, technology

What can the collapse of the Ottoman Empire teach us about the danger of the current discourse around migration? ‘Re-migration' is not a new concept conjured up by the far-right, but rather something that would be familiar to many Europeans of a century ago. What would those involved in these tragedies think of the direction […]

Our politicians don't agree on much, but one thing most of them agree on is that growth is universally good. Grow the pie, they assure us, and there will be more to go around. Our guest on Downstream this week could not disagree more. Professor Jason Hickel argues that the mindless pursuit of Gross Domestic […]