Podcasts about Downstream

Thu, 19 Mar 2026 20:00:00 GMT http://relay.fm/downstream/115 http://relay.fm/downstream/115 Jason Snell Sports Corner! Jason and Will discuss Apple and F1, the FCC and "free" TV sports, World Cup issues, and then we make some TV picks. [Downstream+ subscribers also got to hear us talk a lot about baseball!] Sports Corner! Jason and Will discuss Apple and F1, the FCC and "free" TV sports, World Cup issues, and then we make some TV picks. [Downstream+ subscribers also got to hear us talk a lot about baseball!] clean 2163 Sports Corner! Jason and Will discuss Apple and F1, the FCC and "free" TV sports, World Cup issues, and then we make some TV picks. [Downstream+ subscribers also got to hear us talk a lot about baseball!] This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Will Carroll Links and Show Notes: TV Picks: Will: Blood Coast (Netflix) Jason: Small Prophets (BBC) Get Downstream+ and don't miss a segment! Submit Feedback Under the Knife Injury Territory on YouTube

Rising unemployment, increased military spending, and a decline in living standards for most people, including the middle class: the description fits both the 1930s and the 2020s. In the 1930s, it was a situation that morphed into the destruction and horror of the Second World War. On Downstream with Aaron Bastani this week is Clara […]

• הגאונות האסטרטגית של טראמפ: כיצד ארה"ב משתמשת בשליטה במשאבי הנפט ככלי לריסון סין והשתת עלויות הביטחון על בעלות בריתה.• הזירה האיראנית והאי חארג': המשמעות של תקיפת המתקנים הצבאיים בחארג' והסטטוס של מצרי הורמוז.• ניתוח מניות אנרגיה: הצלחות ב-OXY ו-XLE – ההבדל בין חברות הפקה לזיקוק (Upstream vs. Downstream) וניתוח טכני של "הנשר נחת".• מהפכת ה-AI בלחימה: כיצד אלגוריתמים מנהלים את בנק המטרות בזמן אמת והצפי להיפרדות מהטייס האנושי בשנים הקרובות.• סקירת מניות טכנולוגיה וסווינג: * אזהרות ב-Oracle (ORCL) וב-Meta (פייסבוק).• הזדמנויות סווינג ב-Micron (MU) ו-SanDisk (SNDK).• הלחץ על חברות ה-SaaS והתוכנה: Adobe ו-CRM.• סימן השאלה סביב Palantir (PLTR) למרות המצב הביטחוני.• מניות ביטחוניות בישראל: הביקוש ל-NextVision ו-Smartshooter אל מול חסמי הייצוא ומנגנוני ההגנה של התעשייה הישראלית.• מחיר הנפט לאן? ניתוח חוזים עתידיים, הבדלי ה-Backwardation והצפי לירידת מחירים עתידית.

The dominant structural mechanism highlighted is the industry-wide shift toward liability transfer and governance gaps in AI procurement, deployment, and incident response. According to Dave Sobel, both vendors and organizations are accelerating AI adoption without corresponding investments in oversight, training, or clear accountability structures. This is reflected across multiple sectors, from software vendors such as Grammarly, Eightfold.ai, Cohesity, and Rubrik, to business leaders and policymakers, where risk is systematically deferred downstream rather than managed at the point of adoption. The most consequential evidence is the quantitative disconnect between stated AI priorities and functional oversight. Research cited by Dave Sobel from Economist Impact and HR Dive found that while 38% of organizations budget for AI and 86% of executives rate AI as essential, only 16% offer internal training and over half of department-level AI initiatives lack formal oversight (Ernst & Young). Additionally, 88% of AI vendors limit their liability, and only 17% align with regulatory compliance, per cited surveys, leaving substantial legal and operational risk for end users and service providers. Supporting this trend, Dave Sobel points to Grammarly's opt-out identity usage in new features and a class action lawsuit against Eightfold.ai regarding AI-driven employment decisions. Vendors such as Cohesity, Rubrik, ServiceNow, and Datadog are responding by building tools focused on remediation and recovery from AI-driven incidents, underscoring a shift from preventive governance to reactive containment. Policy moves—such as expanded operational cyber roles for the private sector—further offload accountability without addressing contractual and insurance exposure. For MSPs and technology leaders, these developments create practical risks: unclear service scope around AI tool usage in contracts, increased exposure to billable incidents and legal action, and rising labor costs for incident recovery. Service providers must audit agreements for AI-specific language, distinguish AI-related incidents from standard SLAs, and treat AI governance as a managed risk service. The pressure will increasingly fall on MSPs to account for training gaps, audit trails, compliance attestations, and recovery procedures—not simply the technology itself. Three things to know today 00:00 ROI Reality Check 02:12 Governance Gap Widens 03:14 Cleanup Economy Rises 05:45 Why Do We Care?  Supported by:  CometBackup 

Nearly all of us on Earth live within a ‘nation-state'. Nation-states are an invisible and seemingly inevitable and eternal part of the infrastructure that forms our society: the water we swim in. Rarely do we pause to consider how this global system of nation-states came into being, and what might replace it after its gone. […]

In dieser Podcast-Folge spreche ich mit Daniel Jimenez Schuster, Managing Partner und Mitgründer von iLiMarkets. Daniel ist seit mehr als zwanzig Jahren in der globalen Lithiumindustrie tätig und hat in dieser Zeit unter anderem in führenden Positionen bei SQM gearbeitet. Sein Blick auf Elektromobilität, Batterien und Industriepolitik ist geprägt von Marktdaten, praktischer Erfahrung und einem tiefen Verständnis der gesamten Batterie-Wertschöpfungskette. Im Zentrum unseres Gesprächs steht eine These, die der öffentlichen Debatte widerspricht: Lithium ist nicht das eigentliche Kernproblem der europäischen Energiewende. Während Politik und Öffentlichkeit stark auf Rohstoffe und Versorgungssicherheit fokussieren, sieht Daniel den entscheidenden Engpass an anderer Stelle. Wettbewerbsfähige Batteriezellfertigung fehle in Europa weitgehend. Ohne diese industrielle Basis entstehe weder ein stabiler Bedarf an Kathodenmaterialien noch an Lithiumchemikalien. Sein Leitsatz dazu lautet: Das Upstream folgt dem Downstream. Ein weiterer Schwerpunkt ist die Rolle Chinas im globalen Batteriemarkt. Daniel erklärt, warum China heute eine dominante Stellung innehat und wie Skalierung, Lernkurven und frühe Technologieentscheidungen – insbesondere zugunsten von LFP-Zellen – zu erheblichen Kostenvorteilen geführt haben. Europa und die USA hätten dagegen lange auf andere Zellchemien gesetzt und dadurch mehrere Jahre verloren. Viele aktuell geplante Zellprojekte müssten deshalb neu ausgerichtet werden. Auch industriepolitische Maßnahmen wie Förderprogramme, der Aufbau europäischer Lithiumförderung oder der Critical Raw Materials Act werden kritisch eingeordnet. Daniel argumentiert, dass Europa keinen strukturellen Vorteil im Bergbau habe und öffentliche Mittel besser in Technologie, Industrie und Zellproduktion investiert wären. Rohstoffautarkie allein schaffe keine Wettbewerbsfähigkeit. Ein eigenes Kapitel widmet sich der Direct Lithium Extraction. Diese Technologie wird häufig als nachhaltige Lösung für Europa dargestellt, etwa im Oberrheingraben. Daniel ordnet Chancen und Grenzen realistisch ein und erklärt, warum DLE langfristig relevant sein kann, kurzfristig jedoch kaum ein kostengünstiger Gamechanger ist. Abschließend sprechen wir über Partnerschaften mit China, steigende Lithiumpreise und die Frage, wie Europa industrielle Souveränität erreichen kann. Die zentrale Erkenntnis dieser Folge: Nicht der Rohstoff entscheidet über die Zukunft der Elektromobilität, sondern Know-how, Skalierung und industrielle Umsetzung. Nun aber genug der Einordnung – lasst uns direkt in das Gespräch einsteigen.

Fri, 06 Mar 2026 22:00:00 GMT http://relay.fm/downstream/114 http://relay.fm/downstream/114 Jason Snell We break down the aftermath of the Warner Bros. Discovery sale, including positives for Netflix and questions for Paramount Skydance. We break down the aftermath of the Warner Bros. Discovery sale, including positives for Netflix and questions for Paramount Skydance. clean 3879 We break down the aftermath of the Warner Bros. Discovery sale, including positives for Netflix and questions for Paramount Skydance. Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: Traitors UK (Peacock) Jason: Shrinking (Apple TV) Get Downstream+ and don't miss a segment!

It seems like the frequency of weather-related disasters is increasing. Across the US we're seeing wildfires, tropical storms and hurricanes, extreme heat, extreme cold with snow or ice. And torrential rain leading to a loss of property, life, and livelihoods. What's more, similar extreme events are happening across the globe. These disasters all can have an impact on our food supply and the ability of people to access food. Today, we're speaking with environmental sustainability management expert, Betsy Albright, who is an associate professor of the practice at Duke University's Nicholas School of the Environment. Betsy's research centers on how policies and decisions are made in response to weather related disasters. Interview Summary Betsy, I've been wanting to have you on the podcast for a while, so I'm excited to get you now. So, let's begin with the first broad question. I'd be really interested to learn a little bit more about your research to make sure that our listeners are up to date on it. And I know you really study disasters, but could you explain or expand on what that really means for our listeners? I'm an environmental social scientist who studies the human and social side of disasters. And I ask questions about how climate related disasters or climate driven disasters, or weather disasters affect communities and households. And how individuals perceive risks from disasters, how they're affected by disasters, how they learn from make changes and adapt after disasters. My work started with my dissertation in central Europe. I had a Fulbright in Hungary. But from then I've expanded and moved most of my work to the US context. And our research team and I have done work on flooding and wildfires in Colorado, hurricanes in North Carolina. And I'm also working on a study of the flows of disaster assistance funds from FEMA to communities. And all of this is with or through a lens of equity or inequities and thinking about that across the disaster cycle. This is really important, and I remember being at a conference with you and learning about your work. And I was struck by what happens after the disaster. And in particular what happens to availability of food. And I work with the food bank here in North Carolina. And one of the things I know is when there is a disaster, like when Helene hit Asheville, there are real challenges in getting food out to people. Does your work touch on those topics as well? Yes. I would not say that our work centers on food, but food definitely intersects across all phases of the disaster cycle from preparing for disaster, experiencing disaster, the immediate response- that food bank getting food out- to long term recovery and thinking about risk mitigation. And we can think about that, you know, through a number of different lenses. Both on the food access side, but also on the food systems agriculture side as well. As I mentioned earlier, I take an equity lens on much of the work that we do. It's really important to recognize that disasters hit unevenly across society, across the landscape. Disproportionately they magnify social and environmental stressors that are already there. Communities with limited access to wealth, limited access to food, who are underserved, rural communities, racialized communities, often experience greater impacts from disasters. Disasters occur on top of histories of disenfranchisement. For example, centuries of marginalization of the minoritized Romani peoples of Central Europe they've seen great impacts from flooding. And in North Carolina, Black and African American communities whose ancestors were enslaved and suffered land loss through racist systems of who gets access to loans, access to land ownership. And because of these systems and processes, communities, families, individuals may live on marginal lands, may not own their lands. Their lands may be more prone to flood risk. May be underserved. Their housing may be more at risk. They may rent and not own. May have less agency and resources to repair their homes. And may have less trust in government and government systems. So really thinking about all of that, and then piling on disasters over these centuries of marginalization, disenfranchisement, underinvestment is really critical when trying to disentangle all these processes and develop policy solutions. This is really fascinating work and so thank you for laying out the sort of reality of the experience of disasters where people who have been marginalized may have difficulty accessing resources or there may be some concerns about trust. Broadly, we're interested also in the food system, and I'd be interested to understand how, when disasters strike, do you see effects upon the food system or the food system responding to these disasters? Recognizing that some individuals have higher food stress, even without a disaster, they may have higher pollutant burden because they live next to a concentrated animal feed lot operation. They may have weaker infrastructure systems: electricity, transportation, because of disinvestment. And so, when a disaster strikes, pollution loads may increase, access to food becomes even more of a challenge. Food stress increases. For example, in North Carolina, across the Southeast and further in the United States, Latino migrant farm workers face higher risks during hurricanes and floodings because of barriers, like limited access to emergency information and Spanish language barriers, fears about government intervention, fears tied to immigration status, housing conditions, lack of transportation. And these factors can delay access to food, evacuation, reduce preparedness, slow recovery. And yes, it's a challenge to really think then hard about what policy solutions make sense. That does make me also appreciate when we think about some of the folks involved in the food system, that the disruption that a disaster can bring will also mean a loss of employment or opportunities to continue earning income. And that seems to be a sort of a knock-on effect of these disasters. It's not just the immediate weather event. It's all of the other things that follow afterwards. Yes. And so when thinking about policy solutions, I really think it's critical to address these inequities even outside of the disaster cycle, or outside of the framing of disasters. And can we think about and develop ways, for example, to do reduce the risks of concentrated animal feedlot operations in North Carolina. Other ways for more resilient and sustainable and local ways of farming that minimize environmental risks, increase wealth, increase jobs, access to jobs. That then, when disaster strikes, are going to be more resilient because they're more resilient even before disasters. You know, I'd like to see greater investment in areas of food access, strengthening support for farm workers, encouraging development of local food hubs. Also thinking about making food access hubs more resilient to extreme weather events. Maybe elevating them, getting them all generators or solar microgrids. So that when disaster does happen, they're more resilient and then they can serve as community hubs with less reliance on supply chains at the national level. Really, coming back local, mutual aid, supporting each other, community supporting communities, non-governmental organizations, government, faith-based organizations strengthening local food systems. Also, everything that I just said for food I also think for health. You know, access to healthcare goes along with access to food in terms of critical infrastructure for community to flourish. And so, making sure there are local hospitals, not just in time of disaster, but in time of not disaster. So, expedite funding for small businesses, for neighborhood organizations, neighbors getting to know neighbors in disasters. Neighbors relying on neighbors. And that's critical. Anything we can do to build up networks. And that doesn't necessarily have to be government intervention. That could be faith-based organizations, churches, working with communities. It could be Little Leagues. There's lots of different ways to help build that social infrastructure that's so critical during disasters. Betsy, thank you for that. And as I hear you talk about these issues, what I am grateful for is we normally talk about food and the food system, but it's a parallel reality of what happens with the healthcare system when the disaster strikes. I can only imagine if someone is in need of a certain medicine when the disaster hits access to that medicine may be called into question as happens with food. But one of the big things I get out of what you're saying is we need to build resilient communities. Not when the disaster happens but do that work now. How do we create mutual aid? How do we create actual neighborhoods that know what's going on and to care for one another. Because it's that THAT helps us through these difficult times. Is that a fair assessment? Yes. That's more well said than I said it. So yes. Thank you. I am so grateful for this. Betsy, is there anything else we should think about when it comes to disasters and the food system or how we should prepare for disasters in the future? One thing that I didn't emphasize that my early work really looked at is how we grow food. And in Central Europe and Hungary in the area that I studied, this large-scale infrastructure on land that had previously, centuries ago, been wetlands. And then was drained for large scale agricultural systems, not unlike what we see in much of the Midwest of the United States. But as climate change worsens, we're seeing more extreme rain events. It's becoming harder and harder to basically fight against these floods in our agricultural system. And so really rethinking. What a resilient kind of agroecological system could look like on the food growing side. And that could be issues of what is grown, that could be issues of scale, thinking about maybe we need to put more land aside and not farm. But really thinking hard about how we incentivize, how do we set up insurance to help mitigate some of the risks. But I think that's going to be one of the major challenges moving forward. Bio Elizabeth (Betsy) Albright is the Dan and Bunny Gabel Associate Professor of the Practice of Environmental Ethics and Sustainable Environmental Management at Duke University's Nicholas School for the Environment. Her current research centers on how policies and decisions are made in response to extreme climatic events. She is interested in collaborative decision-making processes, particularly in the realm of water resource management. The Midwest Political Science Associated recently awarded Elizabeth the 'Best Paper by an Emerging Scholar' award at their national conference. Her geographic regions of interest include the southeast US and Central and Eastern Europe. Prior to completing her Ph.D. Elizabeth worked for the State of North Carolina in water resource management.

Episode 502 features Stacey's conversation with Brian Machut (Alliant Health) on how widespread Medicare fee-for-service fraud is inflating costs and undermining ACO shared savings in MSSP and ACO REACH. ACOs uncovered major urinary catheter fraud in 2023 tied to codes A4352/A4353, totaling about $3.5B, with some beneficiaries billed for items never received (including a case shared by Dr. Tara Lagu).  CMS created a "SAHS" (significant, anomalous, highly suspect) process to remove certain suspect costs, but benchmark effects can unevenly impact ACOs; catheter fraud is still projected at $3–$3.5B in 2025. The episode also highlights rapidly growing "skin substitute" spending projected at $13–$15B in 2025; CMS did not classify 2024 skin substitute costs as SAHS, leaving them in ACO performance calculations.  Machut explains this fraud and missed CMS trend projections can reduce provider earnings, discourage participation in value-based care, and potentially drive cost shifting into higher commercial rates—affecting plan sponsors such as self-insured employers. === LINKS ===

In der neuen Folge unseres Soundshot Podcasts sprechen Zeno Grabmayr und Markus Aigner (beide Banking & Finance) über die rechtlichen Rahmenbedingungen für konzerninterne Finanzierungen – von Upstream, Downstream und Sidestream Krediten bis zu den Auswirkungen des Eigenkapitalersatzgesetzes (EKEG) und den Kapitalerhaltungsvorschriften. Sie erläutern die Grundprinzipien der Einlagenrückgewähr nach GmbH- und Aktiengesetz, die Bedeutung des strengen Fremdvergleichs und warum Verstöße zu Nichtigkeit und Organhaftung führen können. Im Fokus stehen die unterschiedlichen Finanzierungsrichtungen im Konzern: Während Downstream Kredite meist unproblematisch sind, gelten Upstream Kredite und Sidestream Kredite als besonders sensibel und sind nur unter engen Voraussetzungen zulässig.Auch die Rolle des EKEG wird behandelt, insbesondere die Frage, wann eine Finanzierung als eigenkapitalersetzend gilt, welche Konsequenzen eine Rückzahlungssperre hat und welche Ansprüche innerhalb des Konzerns entstehen können – etwa bei Weisungen der Konzernmutter.Hören Sie rein und erfahren Sie, welche rechtlichen Risiken und strukturelle Besonderheiten bei konzerninternen Finanzierungen zu beachten sind und wie Unternehmen diese professionell gestalten können. Die Episode ist auf Deutsch verfügbar – auf unserer Website sowie bei Spotify, Apple Podcasts und Amazon Music unter dem Titel Wolf Theiss Soundshot. Für weitere Informationen oder individuelle Rückfragen erreichen Sie uns unter soundshot@wolftheiss.com.

Eligibility errors, missing documentation, and prior authorization gaps may seem small in the moment, but they quietly erode cash flow, inflate AR, and drive avoidable denials. In this episode, we break down why front-end breakdowns still matter most and how AI can either strengthen your foundation or expose the cracks in it.

Is beauty vain, or is beauty, instead, a philosophical treasure that refracts the potency of our inner life force? Is physical beauty something we've programmed to respond to by the 5000 ads a day? Is the obsession with one's own physical beauty a sign of a deeply corrupt soul? If all you have to offer is that which you did not earn, you'll be terrified to lose it. Is the lustful obsession with physical beauty the way of what appears to be a man, but is really an animal? OR is physical beauty a gift from the divine (or evolution if you prefer)? A reward for when we draw nearer to the most metaphorically divine act, that of creating new life in our own image.These are the most pragmatic of philosophical questions. I discuss them with François Vix, who has dedicated the past two decades to advancing health through scientific breakthroughs in the beauty and wellness space. Most notably, he pioneered the use of a stable, bioactive form of SuperOxide Dismutase (SOD), bringing GliSODin to more than 50 countries.I've trialed their two products: GliSODin Anti-Aging and VSOD. These are more than just beauty products, with over 20 clinical trials backing SOD's effect on health and longevity, it may be one of the keys for aspirational beautiful immortals.4:10 Can the pursuit of beauty be virtuous?7:00 The philosophical case for beauty10:33 The science behind SuperOxide Dismutase (SOD)21:44 What is Bioactive SOD-Gliadin Complex?23:27 Origin of Melon-extracted SOD26:45 GliSODin multiplies the effect of mainstream "beauty supplements"29:15 Science: SOD vs free radicals31:31 Effects of GliSODin34:07 Biohacker review of GliSODin35:47 DNA protection - THIS really matters 42:18 GliSODin Anti-Aging vs VSOD44:36 UV Protection - "sunscreen from within?"48:50 GliSODin - Safe for nursing or pregnant mothers?52:22 When to expect results from GliSODin?56:21 Lifestyle cofactors for empowering SOD01:00:47 SOD Nutrient cofactors01:03:31 Cycling SOD supplements?01:07:18 François's personal health practices01:11:15 Entrepreneurship advice01:15:57 Virtue is downstream from investment in healthRead

We walk through the Four Streams of Leadership—reservoir, downstream, upstream, and side stream—and show how leadership is a continuous flow. Reservoir is self-management: values, habits, and the reflection that keeps you steady under pressure. Downstream is team and operations: assembling roles, setting standards, and maintaining momentum. Upstream is partnering with your boss and senior leaders: aligning priorities and preventing strategic drift. Side stream is collaborating with peers: building shared commitments and removing cross-team friction. When each stream runs clean, you move faster with fewer surprises.• reframing the Peter Principle as unpreparedness• replacing stories with explanatory frameworks and exercises• defining the four streams: reservoir, downstream, upstream, side stream• building a culture that holds when we are absent• habits to fill the reservoir: reading, audiobooks, feedback loops• composing teams with visionaries, implementers, and closers• interviewing for role fit through consistent depth• timing process for discovery versus reliability• making disagreement and commitment possible with a clear why• further reading influences: Popper, Feynman, Deutsch• where to learn more and get the bookHiring and team design get specific through three vital roles: visionaries who define the problem and direction, implementers who build the thing, and closers who ship it. Too many visionaries means swirl; too few closers means value never lands. We share interviewing tactics that probe for consistent depth across envisioning, building, and finishing, so you can place people where they thrive. Then we tackle the third rail—process. Early on, heavy process kills discovery; after product-market fit, light process kills reliability. We map the why, when, what, and how of process so your team can innovate without chaos and deliver without drift. Along the way, we unpack “disagree and commit” the right way: explain the why, or you'll get “disagree and resent.”If you're ready to trade fables for frameworks and build a culture that acts the right way when you're not in the room, this conversation is your field guide. Subscribe, share with a manager who just took the leap, and leave a quick review to tell us which framework you'll try first.

The notion that the Global South is affected ‘first and worst' by global shocks they didn't cause, namely climate change, is one of the cornerstones of leftist thought. But what if it's not entirely true? What if, contrary to this tenet, it's wealthy Western nations who have over-developed and lost their resilience in the process? […]

Carl and Dan discuss how Farage trying to copy Rupert Lowe's policies signals the end of the Blairite paradigm.

In 2001, Eric Schlosser published Fast Food Nation: an investigation into the toxic depths of America's food industry.  Twenty five years later, the book remains an urgent intervention, as much for what it says about workers' rights as for our agricultural systems and dietary health. On Downstream this week, Ash Sarkar talks to Eric Schlosser […]

When approaching a project like this I try to come up with a concept quickly - the immediacy of ideas is what makes most sense to me. To me, the sample reminded me of people rapping, and the flow of the original sample seemed to ask for some accompanying electronic instrumentation to give them centre stage. I tried three different approaches and stitched them together - the first part lends itself more to ambient listening, turning the vocals more into an instrument - and the second and third parts would be more at home in a club. I included parts of the sample where the people are also talking/expressing themselves to make it feel like a live jam - that they were also in the room. I think the restriction of not understanding the lyrics can also be an advantage - as the vocals can be used more like an instrument and listeners can focus on the tonality and flow of the words.U'wa group chant reimagined by Richard Corke.———Part of the project A Century of Sounds, reimagining 100 sounds covering 100 years from the collections of the Pitt Rivers Museum at the University of Oxford. Explore the full project at citiesandmemory.com/century-sounds

Nick Warburton's comedy drama returns. It takes us to the Fens and the Platters' boatyard nestled on the river.The Platter community is an eccentric one and at its heart is the chaotic pairing of Pat and his sister Libby. Libby, after a long absence, appears to be back to stay and so does Ravi, the newcomer, who Libby took under her wing. Can they all muddle along together in harmony? Possibly but there are hidden Platter secrets still waiting to be uncovered.Libby ..... Monica Dolan Pat ..... Oliver Chris Ravi ..... Waleed Akhtar Greg ..... Django BevanDirected by Tracey NealeThis second story, narrated by Pat, kicks off with a crisis: Martine, the boatyard Manager (who had a fear of water) has walked out. Her shock departure presents Pat with a problem. Either he runs the boatyard himself or employs someone else. Either idea makes him anxious.Libby proposes a plan. Both her and Ravi will apply for the job. She'll ensure Ravi gets it. Although Ravi has experience (he hasn't) and bristles with good ideas (daydreams), is this ever going to work out for the best?There are gorgeous trips along the river and over to Blake's Island. Plans need to be made to thwart a troublesome visitor. But there are unresolved issues and hidden secrets between Pat and Libby that need to be uncovered.The Writer: Nick Warburton's wonderful, gentle touch with family dramas is no secret to Radio 4 listeners, as shown in Mardle Fen, Holding Back the Tide, Downstream, and The Archers.The Cast: Monica Dolan (Mr Bates vs The Post Office, Sherwood, The Change) Oliver Chris (Rivals, My Lady Jane) Waleed Akhtar (Won an Olivier Award for his play 'The P Word') Django Bevan (2025 BBC Carleton Hobbs winner)Producer & Director: Tracey NealeTechnical Producers: Keith Graham and Sam DickinsonProduction Co-Ordinators: Sara Benaim and Clare EwingThis drama was originally broadcast on BBC Radio 4.

Thu, 19 Feb 2026 02:00:00 GMT http://relay.fm/downstream/113 http://relay.fm/downstream/113 Jason Snell Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) clean 2119 Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: "Best Medicine" (Fox) Jason: "Wonder Man" (Disney+), "Bookish" (PBS) Get Downstream+ and don't miss a segment! Submit Feedback Sky brings together Netflix, Disney+, HBO Max and Hayu into one single subscription, exclusively on Sky | Sky Group DiscussingFilm on X: "The Justice Department has summoned some of the largest movie theater chains in the U.S. for conversations about the impact of a Warner Bros sale. (Source: https://t.co/hPBPx4FMB7) https://t.co/IiAoI65A7B" / X Who Is The Better M

Thu, 19 Feb 2026 02:00:00 GMT http://relay.fm/downstream/113 http://relay.fm/downstream/113 Just Get an Antenna 113 Jason Snell Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) clean 2119 Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: "Best Medicine" (Fox) Jason: "Wonder Man" (Disney+), "Bookish" (PBS) Get Downstream+ and don't miss a segment! Submit Feedback Sky brings together Netflix, Disney+, HBO Max and Hayu into one single subscription, exclusively on Sky | Sky Group DiscussingFilm on X: "The Justice Department has summoned some of the largest movie theater chains in the U.S. for conversations about the impact of a Warner Bros sale. (Source: https://t.co/hPBPx4FMB7) https://t.co/IiAoI65A7B" / X Who Is The Better Marty: Marty

Breast cancer screening is often treated as a given. Mammograms are framed as routine, early detection as unquestionably life-saving, and following guidelines as the responsible choice. But what if the full picture is more complicated?In this episode of hol+, Dr. Taz sits down with integrative oncologist and breast surgeon Dr. Jenn Simmons, author of The Smart Woman's Guide to Breast Cancer, to explore what breast cancer screening data actually shows, where common narratives may oversimplify reality, and how statistics can sometimes be misunderstood by both patients and providers.Together, they discuss the difference between screening and diagnostic imaging, why detecting more cancers does not always mean fewer deaths, and how concepts like overdiagnosis and lead-time bias shape our interpretation of outcomes. Dr. Jenn also explains how breast cancer behaves differently from many other cancers, why progression is not always linear, and what tumor markers like ER, PR, HER2, and triple-negative really indicate.The conversation expands beyond imaging into a whole-body view of breast health, touching on inflammation, immune function, metabolic health, toxic burden, stress, and lifestyle as factors that shape cancer risk and recovery. Rather than promoting fear or urgency, this episode focuses on helping listeners understand their bodies, ask better questions, and make informed decisions with clarity.This episode is for anyone who wants a deeper understanding of breast cancer screening, feels overwhelmed by conflicting guidance, or wants to approach breast health with more nuance and less panic.About Dr. Jenn SimmonsDr. Jenn Simmons is an integrative oncologist, breast surgeon, and founder of Real Health MD. She was Philadelphia's first fellowship-trained breast surgeon and spent nearly two decades leading one of the region's top breast programs before transitioning into integrative oncology.Drawing from her experience in conventional cancer care and her own health journey, Dr. Simmons now focuses on whole-body approaches to breast health, cancer prevention, and recovery, including metabolic health, inflammation, immune function, lifestyle medicine, and root-cause healing. She is the author of The Smart Woman's Guide to Breast Cancer, a patient-centered resource designed to help women better understand their diagnosis, ask informed questions, and navigate treatment decisions with clarity rather than fear.Order the BookThe Smart Woman's Guide to Breast Cancer Stay Connected:Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Jenn SimmonsInstagram: https://www.instagram.com/drjennsimmonsYouTube: https://www.youtube.com/@dr.jennsimmonsWebsite: https://www.jennsimmonsmd.com/Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)00:00 Swedish trial claim and overdiagnosis framing 00:52 Why this became a part two conversation 03:25 Reframing screening narratives and medical training gaps 04:39 Why Dr. Simmons questions mammograms as a screening tool 06:06 Origins of screening programs and “invitation to screen” bias 07:12 Relative risk vs absolute numbers example (4 vs 5 per 1,000) 08:49 Overdiagnosis explained with a vivid analogy 09:50 Autopsy-study claim and the “microscopic cancer” idea 12:11 Swedish trial claim revisited: more diagnoses, same deaths 13:38 Downstream harms: callbacks, biopsies, overtreatment 15:04 Lead-time bias and survival statistics explained 16:44 Dr. Simmons' view on the founder's regret narrative 18:16 Switzerland headline clarified and what actually changed 20:10 Cautionary stories and aggressive cancers discussion 22:07 Why breast cancer does not always progress linearly 24:21 Buckets: DCIS, invasive, inflammatory, receptor types 26:15 Clinical vs subclinical disease approach 28:25 Long-term tradeoffs and “forgotten woman” after treatment 32:15 What ER PR HER2 mean biologically and system incentives 35:33 Testosterone discussion and prevention claim presented 42:15 Hormones after breast cancer and the 4-year “reintroduction” idea 44:29 Triple negative: environment, toxicity, immune system focus 49:19 What to do next: pause, exceptions, whole-body workup 52:32 Prevention and breast health approach begins 53:24 At-home tears test explanation (as discussed) 56:24 Detox basics and why sweating is emphasized 59:34 Imaging preferences for screening and what to do if limited access

Just a week ago, the architect of Starmer's rise to power, Morgan McSweeney, resigned over his connections to Peter Mandelson, after further proof of Mandelson's involvement with Jeffrey Epstein emerged in the newest batch of files released by the US Department of Justice. According to this week's guest, this scandal isn't an anomaly, but an […]

Stephen Grootes speaks to Martyn Davis, Chairman of the Downstream & Industrial Committee, at the Investing in African Mining Indaba about how aligning domestic beneficiation with the growth of Africa’s automotive sector can deepen localisation, boost component production, and stimulate sustainable economic development. The Money Show is a podcast hosted by well-known journalist and radio presenter, Stephen Grootes. He explores the latest economic trends, business developments, investment opportunities, and personal finance strategies. Each episode features engaging conversations with top newsmakers, industry experts, financial advisors, entrepreneurs, and politicians, offering you thought-provoking insights to navigate the ever-changing financial landscape.    Thank you for listening to a podcast from The Money Show Listen live Primedia+ weekdays from 18:00 and 20:00 (SA Time) to The Money Show with Stephen Grootes broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3Nk For more from the show, go to https://buff.ly/7QpH0jY or find all the catch-up podcasts here https://buff.ly/PlhvUVe Subscribe to The Money Show Daily Newsletter and the Weekly Business Wrap here https://buff.ly/v5mfetc The Money Show is brought to you by Absa     Follow us on social media   702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/CapeTalk 702 on YouTube: https://www.youtube.com/@radio702   CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/Radio702 CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

When it comes to the relationship between capitalism and crime, those on the left generally think of exploitation. People often turn to crime, so the thinking goes, because they can't make ends meet by legitimate means. Whatever your views on that framing, there is also another – far less discussed – connection between capitalism and […]

Over the past three years, the Israeli genocide of the Palestinian people has become a flash point for freedom of speech in the West. Expressing solidarity with Palestinians has given Western governments an excuse to crack down on dissenters. There has been intimidation and job insecurity at one end of the scale, through to brutal […]

Mon, 02 Feb 2026 18:30:00 GMT http://relay.fm/downstream/112 http://relay.fm/downstream/112 Jason Snell It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. clean 3634 It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. This episode of Downstream is sponsored by: Ecamm: Powerful live streaming platform for Mac. Guest Starring: Will Carroll Links and Show Notes: TV Picks Will: Wonder Man (Disney+) Jason: Riot Women (BritBox) Get Downstream+ and don't miss a segment! Submit Feedback

Mon, 02 Feb 2026 18:30:00 GMT http://relay.fm/downstream/112 http://relay.fm/downstream/112 Marshawn on the Golf Cart 112 Jason Snell It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. clean 3634 It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. This episode of Downstream is sponsored by: Ecamm: Powerful live streaming platform for Mac. Guest Starring: Will Carroll Links and Show Notes: TV Picks Will: Wonder Man (Disney+) Jason: Riot Women (BritBox) Get Downstream+ and don't miss a segment! Submit Feedback

Recorded live at Cloud Connections, the Cloud Communications Alliance event in Delray Beach, Doug Green, Publisher of Technology Reseller News, spoke with Bill Placke, Co-Founder & President, Americas at SecurePII, about one of the most pressing challenges facing AI-driven communications today: how to scale AI while complying with global data privacy regulations—and how that challenge can become a competitive advantage. Placke explains that SecurePII was formed to address a growing structural problem in AI adoption. While organizations are eager to deploy AI and train large language models, regulatory uncertainty around personally identifiable information (PII) has stalled progress. Citing industry research showing that more than 60 percent of AI initiatives have been paused due to data privacy concerns, Placke argues that governance policies alone are not enough. Instead, SecurePII takes an architectural approach. At the core of SecurePII's solution is data minimization at the point of ingestion. The company's technology prevents sensitive information—such as credit card numbers, names, addresses, or social security numbers—from ever entering enterprise systems. SecurePII's existing PCI-focused offering already removes cardholder data from call flows, keeping organizations out of PCI scope entirely. The same approach is now being extended to broader categories of PII, enabling AI systems to operate and train on clean data streams that are free from regulated information. Placke emphasizes that this upstream architectural design fundamentally changes the compliance equation. Regulators and plaintiff attorneys, he notes, care about outcomes—not intent. If sensitive data never enters the system, compliance scope, audit costs, breach exposure, and regulatory risk are dramatically reduced. “Downstream controls don't scale with AI—architecture does,” Placke says, positioning data minimization as a foundation for both trust and growth. The discussion also highlights the role of consent and customer trust in an AI-enabled world. Rather than asking customers to consent to broad data use, SecurePII enables enterprises to clearly state that sensitive information is neither seen nor stored, while still allowing AI to learn from outcomes and sentiment. This approach removes what Placke calls the “creepy factor” associated with AI and personal data, while aligning with emerging frameworks such as the EU AI Act and long-standing NIST guidance. For MSPs, UCaaS providers, and channel partners, Placke frames compliance not as a cost center but as a revenue opportunity. By embedding privacy-preserving architectures into voice, AI, and communications solutions, service providers can differentiate themselves as trusted advisors—helping customers deploy AI safely, reduce regulatory exposure, and accelerate adoption. To learn more about SecurePII and its privacy-first AI architecture, visit https://www.securepii.cloud/.

This week, Donald Trump continued his streak of threatening tariffs against any country that opposes him, increasing the odds of an escalating trade war and further destabilising the global economic system. But according to this week's guest, the system is in desperate need of reform. Indeed, she thinks without a complete structural overhaul, it will […]

Fri, 23 Jan 2026 21:45:00 GMT http://relay.fm/downstream/111 http://relay.fm/downstream/111 Jason Snell Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) clean 2277 Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) This episode of Downstream is sponsored by: Ecamm: Powerful live streaming platform for Mac. Links and Show Notes: TV Picks: Joe: All Creatures Great and Small (PBS) Jason: A Knight of the Seven Kingdoms (HBO Max) Get Downstream+ and don't miss a segment! Submit Feedback Can Larry and David Ellison's Oracle Money Buy Hollywood? How Netflix's Sony Deal Explains Its Warners Pursuit - Puck

Fri, 23 Jan 2026 21:45:00 GMT http://relay.fm/downstream/111 http://relay.fm/downstream/111 Think of Netflix as Pac-Man 111 Jason Snell Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) clean 2277 Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) This episode of Downstream is sponsored by: Ecamm: Powerful live streaming platform for Mac. Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: All Creatures Great and Small (PBS) Jason: A Knight of the Seven Kingdoms (HBO Max) Get Downstream+ and don't miss a segment! Submit Feedback Can Larry and David Ellison's Oracle Money Buy Hollywood? How Netflix's Sony Deal Explains Its Warners Pursuit - Puck

In this encore episode, we detail connections between H. pylori and hypochlorhydria, while highlighting possible downstream effects on nutrient absorption. We examine how reduced gastric acidity can impair the liberation and assimilation of certain micronutrients, including iron, calcium, vitamin B12, and more; and we further discuss the impact of low stomach acid upon downstream digestive enzyme activation and gut microbial balance. Topics:1. Hypochlorhydria - Low stomach acid.2. H. pylori 3. Gastric Anatomy & Layers- The stomach: hollow, muscular organ for mechanical and chemical digestion.- Regions: Cardia, fundus, body, and pylorus.- Layers: Mucosa, Submucosa, Muscularis externa, Serosa4. Mucosal Layer - Surface mucous cells secrete a thick bicarbonate-rich, protective mucus.- Gastric pits lead to gastric glands, which contain specialized secretory cells.5. Specialized Gastric Cells- Parietal Cells: Secrete hydrochloric acid (HCl) and intrinsic factor (IF).- Chief Cells: Secrete pepsinogen (converted to pepsin by HCl) and gastric lipase.- Role of HCl: Activates pepsin, denatures proteins, and contributes to nutrient absorption.- Intrinsic factor and vitamin B12 absorption.6. Vitamin B12 Absorption- Essential for DNA synthesis, RBC formation, neurological function.- Released from food proteins by gastric acid and pepsin.- Impaired absorption.7. Role of Gastric Acid in Broader Micronutrient Absorption- Absorption of minerals.- Soluble, ionized state.- Iron: HCl aids in preventing insoluble precipitates and supports iron absorption.8. Protective Role of Gastric Acid- Acts as a line of defense against ingested pathogens.- Maintains low microbial diversity in the stomach.- Low HCl and Small Intestinal Bacterial Overgrowth.9. Symptoms of Low Stomach Acid- Bloating, early satiety, excessive belching.- Undigested food in stool, chronic constipation.- May reflect impaired enzymatic activation and digestive insufficiency.10. Conclusion- Multifactorial causes and downstream effects.- Optimal range, neither high nor low.Thank you to our episode sponsor: 1. "Longevity" with Protein, Probiotics, Bovine Colostrum, Collagen, and More. Use code CHLOE for 25% off.*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.Thanks for tuning in!Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Joe Poirot joins the conversation and we go deep on vintage slab transitions, grading risk, and the psychology of the “slab premium.” Jonathan explains how he moved major cards out of BVG holders without mailing them, including an in person handoff to SGC at Fenway, and why a newer holder can feel like a safer asset even with a downgrade. Then we zoom out to the bigger question sparked by a High Pop Professor video: is the hobby becoming a “house of slabs,” and are we still trapped in cult like grading behavior? We also hit the uncomfortable part: older high grade cards that might not hold up to today's standards. If collectors pay today's money for “imposter” high grades and later feel burned, that can shake confidence, push people out of the market, and create downstream damage. Joe breaks down why this risk depends heavily on the lane, with real differences between ultra modern gem rates, 90s inserts, and classic 80s cardboard where PSA 9 to PSA 10 gaps can feel irrational. In this part, we cover: BVG to SGC and PSA crossovers, and how to do it without mailing grails Downgrades, security, and why a newly graded holder can feel safer PSA owning SGC and Beckett and what that does to collector psychology The “same card” thought experiment and whether the holder is the product Older “imposter” high grades and how changing standards create hidden risk Why buyers getting burned could ripple downstream across the market Gradeflation, resubmission incentives, and who ends up holding the bag Why 10s matter in some lanes, and barely matter in others Follow Sports Cards Live on Apple Podcasts, Spotify, or wherever you listen Subscribe to Sports Cards Live on YouTube for full episodes and live shows Leave a rating and review to help more collectors find the show Share this episode with a collector who's chasing old 10s or debating a crossover Follow @jlee_sportscardslive on Instagram for clips and updates Take the Hobby Spectrum assessment and request your access code at TheHobbySpectrum.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Our guest this week was born in 1943, in what was then British India – modern day Pakistan. Unlike most, who have learned history through books and second-hand sources, he has witnessed first-hand a great deal of the 20th and 21st centuries. Tariq Ali founded Verso Books, the leading left-wing publishing house in Britain, as well […]

Goose visits Downstream for the first time.For Pookajutsu ♥️Catch us live every Sunday at 14:00 on ⁠https://www.youtube.com/@RPGClinic/videos⁠Blue Sky: ⁠https://bsky.app/profile/rpgclinic.bsky.social⁠Website: ⁠http://www.rpgclinic.com/⁠Wiki: ⁠https://rpgclinic.fandom.com/wiki/⁠Discord server: ⁠https://discord.com/invite/kenG3xu⁠An RPGClinic campaign promises committed storytelling and performances, professional tech, dynamic overlays, and info boxes to keep the system accessible to new viewers. Games swing between comedy and drama at the drop of a hat. There will be laughter. There will be tears. There will definitely be double-entendres.

It has been a bellicose start to 2026, with the US army kidnapping Venezuelan President Nicolas Maduro and threatening to annex Greenland, putting many more nations, including Mexico and Colombia, on high alert. On Downstream this week is investigative journalist Glenn Greenwald, who's best known for helping Edward Snowden's disclosures about the NSA's global surveillance […]

Thu, 08 Jan 2026 22:45:00 GMT http://relay.fm/downstream/110 http://relay.fm/downstream/110 Jason Snell Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. clean 4305 Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Casey Liss Links and Show Notes: Our Picks: Jason: Down Cemetery Road (Apple TV), The Pitt (HBO Max) Casey: Shoresy (Hulu) Get Downstream+ and don't miss a segment! Submit Feedback Channels — TV Everywhere Is cablecard sup

Thu, 08 Jan 2026 22:45:00 GMT http://relay.fm/downstream/110 http://relay.fm/downstream/110 I See Spreadsheets In My Future 110 Jason Snell Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. clean 4305 Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Casey Liss Links and Show Notes: Our Picks: Jason: Down Cemetery Road (Apple TV), The Pitt (HBO Max) Casey: Shoresy (Hulu) Get Downstream+ and don't miss a segment! Submit Feedback Channels — TV Everywhere Is cablecard support ACTUAL

For over 4,000 years, silkworms have connected civilizations through ancient trade routes. Now, KAICO Ltd., a Japanese biotech spin-off from Kyushu University, is transforming these creatures into living bioreactors capable of producing complex recombinant proteins and vaccine antigens—without the bioreactors, expensive media, or massive water consumption of conventional platforms.Masafumi Osawa, Business Development Lead at KAICO, brings an unconventional path to biotech. Trained in cultural anthropology with fieldwork experience in Indonesia, he witnessed firsthand the healthcare disparities that drive his current mission. After years in pharmaceutical business development at Towa Pharmaceutical, he joined KAICO to help scale a technology he believes could reshape global vaccine accessibility. His cross-cultural expertise now proves invaluable as KAICO expands internationally, with active partnerships in Vietnam and Thailand and growing interest from other regions.Episode highlights:Masafumi's transition from anthropology to biotech, and how cross-cultural expertise benefits global health collaborations. (04:15)The founding story of KAICO, spun out from Kyushu University and focused on recombinant proteins and vaccine antigen production (08:45)Step-by-step overview of the silkworm baculovirus expression system, including pupae handling and bioprocessing basics. (10:28)Practical differences between silkworms, E. coli, mammalian, and insect cell culture platforms—exploring advantages and drawbacks. (13:10)Strategies KAICO uses to control silkworm variability, including SPF grade sourcing, diet, environment, and documentation for pharmaceutical acceptance. (15:08)Production scalability: a single pupa can match 100–1000 ml of insect cell culture, with major implications for cost and environmental footprint. (16:42)Downstream harvesting and purification—how KAICO extracts and processes proteins from silkworm pupae, keeping methods largely familiar to traditional systems. (19:31)Regulatory and GMP challenges of using live organisms, and KAICO's approach to satisfying authorities and ensuring product consistency. (21:43)Whether you're curious about alternative biomanufacturing methods or want a transparent look at silkworm-based protein expression from research to the clinic, this episode delivers practical insights and thoughtful discussion.Connect with Masafumi Osawa:LinkedIn: www.linkedin.com/in/masa-osawaKAICO Ltd.: www.kaicoltd.jp/enNext step:Need fast CMC guidance? → Get rapid CMC decision support hereOne bad CDMO decision can cost you two years and your Series A. If you're navigating tech transfer, CDMO selection, or IND prep, let's talk before it gets expensive. Two slots open this month.Support the show

After ‘Operation Al-Aqsa Flood' on October 7th, a specific narrative quickly emerged and pervaded the entire Western mainstream media. Namely, that unprecedented horrors were committed against the state of Israel and that whatever way it responded was justified. Any deviation from this narrative was quickly shut down. In the intervening years, the British state has […]

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the benefit of shunts in idiopathic normal-pressure hydrocephalus, how neurologists drive downstream revenue, and anticoagulant monotherapy after stroke.

Ash Sarkar and Aaron Bastani joined each other on 17th December for a special end-of-year Downstream, wrapping up the year in politics.

Norman Finkelstein is one of the west's leading anti-Zionist scholars. The son of Holocaust survivors, he has spent his life studying and critiquing Israel's assault on Palestine, decades before it became socially acceptable to do so. Yet despite having dedicated his career to it, by the day before Hamas' attack in October 2023, Norman had […]

Thu, 18 Dec 2025 00:15:00 GMT http://relay.fm/downstream/109 http://relay.fm/downstream/109 Jason Snell Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. clean 3871 Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. Guest Starring: Tim Goodman Links and Show Notes: Shows mentioned: Black Summer (Netflix), Severance (Apple TV), The Studio (Apple TV), Families Like Ours (Denmark; Netflix), Pluribus (Apple TV), The Diplomat (Netflix), The Bear (Hulu), Asura (Japan; Netflix), The American Revolution (PBS), Slow Horses (Apple TV), Adolescence (Netflix), Department Q (Netflix), Ludwig (BBC/Britbox), Nine Puzzles (Korea; Hulu), Deli Boys (Hulu), The Trunk (Korea; Netflix), Karma (Korea; Netflix), Trigger (Korea; Netflix), My Name (Korea; Netflix), Extracurricular (Korea; Netflix). Get Downstream+ and don't miss a segment! Submit Feedback Downstream #85: A Holiday Visit from Tim Goodman - Relay Stream Inte

[Cross-posted from Downstream #109 on Relay FM.] Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, “Pluribus,” and his top shows of the year. Tim Goodman and Jason Snell.

Since Hamas launched its assault on October 7th, 2023, the group has become synonymous with evil in large parts of the Western media. Condemnation has come at the expense of critical engagement with the group's actions, objectives, and history, leaving a vacuum that has been filled with racist assumptions and conspiracy theories. Tareq Baconi is […]

Fri, 12 Dec 2025 00:00:00 GMT http://relay.fm/downstream/108 http://relay.fm/downstream/108 Jason Snell Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) clean 1693 Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: Get Downstream+ and don't miss a segment! Submit Feedback Disney Agrees to Bring Its Characters to OpenAI's Sora Videos - The New York Times Bob Iger's L

Fri, 12 Dec 2025 00:00:00 GMT http://relay.fm/downstream/108 http://relay.fm/downstream/108 Darth Vader Versus Ariel 108 Jason Snell Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) clean 1693 Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: Get Downstream+ and don't miss a segment! Submit Feedback Disney Agrees to Bring Its Characters to OpenAI's Sora Videos - The New York Times Bob Iger's Latest Legac

Did you know that the standard of Google searches has actually gotten worse over recent years? Once you think about it, it makes sense. Highly effective search means fewer searches overall. And fewer searches means less ad revenue. The financial basis of Alphabet, which is Google's parent company, is, of course, digital advertising. Which means […]

Whether you love or loathe his tactics, it's hard to deny the disruptive impact that Roger Hallam has had on British politics via the activist organisations he has led, Extinction Rebellion and Just Stop Oil. He joins Ash Sarkar fresh from his latest stint in prison, where he wrote a treatise for Your Party that […]