Podcasts about Downstream

Nick Warburton's comedy drama returns. It takes us to the Fens and the Platters' boatyard nestled on the river.The Platter community is an eccentric one and at its heart is the chaotic pairing of Pat and his sister Libby. Libby, after a long absence, appears to be back to stay and so does Ravi, the newcomer, who Libby took under her wing. Can they all muddle along together in harmony? Possibly but there are hidden Platter secrets still waiting to be uncovered.Libby ..... Monica Dolan Pat ..... Oliver Chris Ravi ..... Waleed Akhtar Greg ..... Django BevanDirected by Tracey NealeThis second story, narrated by Pat, kicks off with a crisis: Martine, the boatyard Manager (who had a fear of water) has walked out. Her shock departure presents Pat with a problem. Either he runs the boatyard himself or employs someone else. Either idea makes him anxious.Libby proposes a plan. Both her and Ravi will apply for the job. She'll ensure Ravi gets it. Although Ravi has experience (he hasn't) and bristles with good ideas (daydreams), is this ever going to work out for the best?There are gorgeous trips along the river and over to Blake's Island. Plans need to be made to thwart a troublesome visitor. But there are unresolved issues and hidden secrets between Pat and Libby that need to be uncovered.The Writer: Nick Warburton's wonderful, gentle touch with family dramas is no secret to Radio 4 listeners, as shown in Mardle Fen, Holding Back the Tide, Downstream, and The Archers.The Cast: Monica Dolan (Mr Bates vs The Post Office, Sherwood, The Change) Oliver Chris (Rivals, My Lady Jane) Waleed Akhtar (Won an Olivier Award for his play 'The P Word') Django Bevan (2025 BBC Carleton Hobbs winner)Producer & Director: Tracey NealeTechnical Producers: Keith Graham and Sam DickinsonProduction Co-Ordinators: Sara Benaim and Clare EwingThis drama was originally broadcast on BBC Radio 4.

Thu, 19 Feb 2026 02:00:00 GMT http://relay.fm/downstream/113 http://relay.fm/downstream/113 Jason Snell Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) clean 2119 Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: "Best Medicine" (Fox) Jason: "Wonder Man" (Disney+), "Bookish" (PBS) Get Downstream+ and don't miss a segment! Submit Feedback Sky brings together Netflix, Disney+, HBO Max and Hayu into one single subscription, exclusively on Sky | Sky Group DiscussingFilm on X: "The Justice Department has summoned some of the largest movie theater chains in the U.S. for conversations about the impact of a Warner Bros sale. (Source: https://t.co/hPBPx4FMB7) https://t.co/IiAoI65A7B" / X Who Is The Better M

Thu, 19 Feb 2026 02:00:00 GMT http://relay.fm/downstream/113 http://relay.fm/downstream/113 Just Get an Antenna 113 Jason Snell Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) clean 2119 Main Street goes bust, the Super Bowl soars, the Winter Olympics rule, and the Great Rebundling proceeds apace. Plus: our TV picks! [Downstream+ subscribers also get: Big changes at Disney, and the lastest on WBD/Netflix/Paramount.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: "Best Medicine" (Fox) Jason: "Wonder Man" (Disney+), "Bookish" (PBS) Get Downstream+ and don't miss a segment! Submit Feedback Sky brings together Netflix, Disney+, HBO Max and Hayu into one single subscription, exclusively on Sky | Sky Group DiscussingFilm on X: "The Justice Department has summoned some of the largest movie theater chains in the U.S. for conversations about the impact of a Warner Bros sale. (Source: https://t.co/hPBPx4FMB7) https://t.co/IiAoI65A7B" / X Who Is The Better Marty: Marty

Breast cancer screening is often treated as a given. Mammograms are framed as routine, early detection as unquestionably life-saving, and following guidelines as the responsible choice. But what if the full picture is more complicated?In this episode of hol+, Dr. Taz sits down with integrative oncologist and breast surgeon Dr. Jenn Simmons, author of The Smart Woman's Guide to Breast Cancer, to explore what breast cancer screening data actually shows, where common narratives may oversimplify reality, and how statistics can sometimes be misunderstood by both patients and providers.Together, they discuss the difference between screening and diagnostic imaging, why detecting more cancers does not always mean fewer deaths, and how concepts like overdiagnosis and lead-time bias shape our interpretation of outcomes. Dr. Jenn also explains how breast cancer behaves differently from many other cancers, why progression is not always linear, and what tumor markers like ER, PR, HER2, and triple-negative really indicate.The conversation expands beyond imaging into a whole-body view of breast health, touching on inflammation, immune function, metabolic health, toxic burden, stress, and lifestyle as factors that shape cancer risk and recovery. Rather than promoting fear or urgency, this episode focuses on helping listeners understand their bodies, ask better questions, and make informed decisions with clarity.This episode is for anyone who wants a deeper understanding of breast cancer screening, feels overwhelmed by conflicting guidance, or wants to approach breast health with more nuance and less panic.About Dr. Jenn SimmonsDr. Jenn Simmons is an integrative oncologist, breast surgeon, and founder of Real Health MD. She was Philadelphia's first fellowship-trained breast surgeon and spent nearly two decades leading one of the region's top breast programs before transitioning into integrative oncology.Drawing from her experience in conventional cancer care and her own health journey, Dr. Simmons now focuses on whole-body approaches to breast health, cancer prevention, and recovery, including metabolic health, inflammation, immune function, lifestyle medicine, and root-cause healing. She is the author of The Smart Woman's Guide to Breast Cancer, a patient-centered resource designed to help women better understand their diagnosis, ask informed questions, and navigate treatment decisions with clarity rather than fear.Order the BookThe Smart Woman's Guide to Breast Cancer Stay Connected:Connect further to Hol+ at https://holplus.co/- Don't forget to like, subscribe, and hit the notification bell to stay updated on future episodes of hol+.Follow Dr. Jenn SimmonsInstagram: https://www.instagram.com/drjennsimmonsYouTube: https://www.youtube.com/@dr.jennsimmonsWebsite: https://www.jennsimmonsmd.com/Follow Dr. Taz on Instagram: https://www.instagram.com/drtazmd/https://www.instagram.com/liveholplus/Subscribe to the audio podcast: https://holplus.transistor.fm/subscribeSubscribe to the video podcast: https://www.youtube.com/@DrTazMD/podcastsGet your copy of The Hormone Shift: Balance Your Body and Thrive Through Midlife and MenopauseHost & Production TeamHost: Dr. Taz; Produced by ClipGrowth.com (Producer: Pat Gostek)00:00 Swedish trial claim and overdiagnosis framing 00:52 Why this became a part two conversation 03:25 Reframing screening narratives and medical training gaps 04:39 Why Dr. Simmons questions mammograms as a screening tool 06:06 Origins of screening programs and “invitation to screen” bias 07:12 Relative risk vs absolute numbers example (4 vs 5 per 1,000) 08:49 Overdiagnosis explained with a vivid analogy 09:50 Autopsy-study claim and the “microscopic cancer” idea 12:11 Swedish trial claim revisited: more diagnoses, same deaths 13:38 Downstream harms: callbacks, biopsies, overtreatment 15:04 Lead-time bias and survival statistics explained 16:44 Dr. Simmons' view on the founder's regret narrative 18:16 Switzerland headline clarified and what actually changed 20:10 Cautionary stories and aggressive cancers discussion 22:07 Why breast cancer does not always progress linearly 24:21 Buckets: DCIS, invasive, inflammatory, receptor types 26:15 Clinical vs subclinical disease approach 28:25 Long-term tradeoffs and “forgotten woman” after treatment 32:15 What ER PR HER2 mean biologically and system incentives 35:33 Testosterone discussion and prevention claim presented 42:15 Hormones after breast cancer and the 4-year “reintroduction” idea 44:29 Triple negative: environment, toxicity, immune system focus 49:19 What to do next: pause, exceptions, whole-body workup 52:32 Prevention and breast health approach begins 53:24 At-home tears test explanation (as discussed) 56:24 Detox basics and why sweating is emphasized 59:34 Imaging preferences for screening and what to do if limited access

Just a week ago, the architect of Starmer's rise to power, Morgan McSweeney, resigned over his connections to Peter Mandelson, after further proof of Mandelson's involvement with Jeffrey Epstein emerged in the newest batch of files released by the US Department of Justice. According to this week's guest, this scandal isn't an anomaly, but an […]

Stephen Grootes speaks to Martyn Davis, Chairman of the Downstream & Industrial Committee, at the Investing in African Mining Indaba about how aligning domestic beneficiation with the growth of Africa’s automotive sector can deepen localisation, boost component production, and stimulate sustainable economic development. The Money Show is a podcast hosted by well-known journalist and radio presenter, Stephen Grootes. He explores the latest economic trends, business developments, investment opportunities, and personal finance strategies. Each episode features engaging conversations with top newsmakers, industry experts, financial advisors, entrepreneurs, and politicians, offering you thought-provoking insights to navigate the ever-changing financial landscape.    Thank you for listening to a podcast from The Money Show Listen live Primedia+ weekdays from 18:00 and 20:00 (SA Time) to The Money Show with Stephen Grootes broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3Nk For more from the show, go to https://buff.ly/7QpH0jY or find all the catch-up podcasts here https://buff.ly/PlhvUVe Subscribe to The Money Show Daily Newsletter and the Weekly Business Wrap here https://buff.ly/v5mfetc The Money Show is brought to you by Absa     Follow us on social media   702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/CapeTalk 702 on YouTube: https://www.youtube.com/@radio702   CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/Radio702 CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

When it comes to the relationship between capitalism and crime, those on the left generally think of exploitation. People often turn to crime, so the thinking goes, because they can't make ends meet by legitimate means. Whatever your views on that framing, there is also another – far less discussed – connection between capitalism and […]

Over the past three years, the Israeli genocide of the Palestinian people has become a flash point for freedom of speech in the West. Expressing solidarity with Palestinians has given Western governments an excuse to crack down on dissenters. There has been intimidation and job insecurity at one end of the scale, through to brutal […]

Mon, 02 Feb 2026 18:30:00 GMT http://relay.fm/downstream/112 http://relay.fm/downstream/112 Jason Snell It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. clean 3634 It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. This episode of Downstream is sponsored by: Ecamm: Powerful live streaming platform for Mac. Guest Starring: Will Carroll Links and Show Notes: TV Picks Will: Wonder Man (Disney+) Jason: Riot Women (BritBox) Get Downstream+ and don't miss a segment! Submit Feedback

Mon, 02 Feb 2026 18:30:00 GMT http://relay.fm/downstream/112 http://relay.fm/downstream/112 Marshawn on the Golf Cart 112 Jason Snell It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. clean 3634 It's Super Bowl week and the start of the Olympics, so Will Carroll joins Jason to discuss Peacock's almost-make-or-break moment, streaming fights and wrestling, and the fate of a clutch of Regional Sports Networks and other cable channels. This episode of Downstream is sponsored by: Ecamm: Powerful live streaming platform for Mac. Guest Starring: Will Carroll Links and Show Notes: TV Picks Will: Wonder Man (Disney+) Jason: Riot Women (BritBox) Get Downstream+ and don't miss a segment! Submit Feedback

Recorded live at Cloud Connections, the Cloud Communications Alliance event in Delray Beach, Doug Green, Publisher of Technology Reseller News, spoke with Bill Placke, Co-Founder & President, Americas at SecurePII, about one of the most pressing challenges facing AI-driven communications today: how to scale AI while complying with global data privacy regulations—and how that challenge can become a competitive advantage. Placke explains that SecurePII was formed to address a growing structural problem in AI adoption. While organizations are eager to deploy AI and train large language models, regulatory uncertainty around personally identifiable information (PII) has stalled progress. Citing industry research showing that more than 60 percent of AI initiatives have been paused due to data privacy concerns, Placke argues that governance policies alone are not enough. Instead, SecurePII takes an architectural approach. At the core of SecurePII's solution is data minimization at the point of ingestion. The company's technology prevents sensitive information—such as credit card numbers, names, addresses, or social security numbers—from ever entering enterprise systems. SecurePII's existing PCI-focused offering already removes cardholder data from call flows, keeping organizations out of PCI scope entirely. The same approach is now being extended to broader categories of PII, enabling AI systems to operate and train on clean data streams that are free from regulated information. Placke emphasizes that this upstream architectural design fundamentally changes the compliance equation. Regulators and plaintiff attorneys, he notes, care about outcomes—not intent. If sensitive data never enters the system, compliance scope, audit costs, breach exposure, and regulatory risk are dramatically reduced. “Downstream controls don't scale with AI—architecture does,” Placke says, positioning data minimization as a foundation for both trust and growth. The discussion also highlights the role of consent and customer trust in an AI-enabled world. Rather than asking customers to consent to broad data use, SecurePII enables enterprises to clearly state that sensitive information is neither seen nor stored, while still allowing AI to learn from outcomes and sentiment. This approach removes what Placke calls the “creepy factor” associated with AI and personal data, while aligning with emerging frameworks such as the EU AI Act and long-standing NIST guidance. For MSPs, UCaaS providers, and channel partners, Placke frames compliance not as a cost center but as a revenue opportunity. By embedding privacy-preserving architectures into voice, AI, and communications solutions, service providers can differentiate themselves as trusted advisors—helping customers deploy AI safely, reduce regulatory exposure, and accelerate adoption. To learn more about SecurePII and its privacy-first AI architecture, visit https://www.securepii.cloud/.

This week, Donald Trump continued his streak of threatening tariffs against any country that opposes him, increasing the odds of an escalating trade war and further destabilising the global economic system. But according to this week's guest, the system is in desperate need of reform. Indeed, she thinks without a complete structural overhaul, it will […]

Fri, 23 Jan 2026 21:45:00 GMT http://relay.fm/downstream/111 http://relay.fm/downstream/111 Jason Snell Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) clean 2277 Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) This episode of Downstream is sponsored by: Ecamm: Powerful live streaming platform for Mac. Links and Show Notes: TV Picks: Joe: All Creatures Great and Small (PBS) Jason: A Knight of the Seven Kingdoms (HBO Max) Get Downstream+ and don't miss a segment! Submit Feedback Can Larry and David Ellison's Oracle Money Buy Hollywood? How Netflix's Sony Deal Explains Its Warners Pursuit - Puck

Fri, 23 Jan 2026 21:45:00 GMT http://relay.fm/downstream/111 http://relay.fm/downstream/111 Think of Netflix as Pac-Man 111 Jason Snell Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) clean 2277 Netflix and Paramount continue their battle for Warner, why Ted Sarandos might not be the villain he's painted to be, plus letters and TV picks. (Downstream+ listeners also get: YouTube's letter, Oscar noms, Star Search, and Heated Rivalry.) This episode of Downstream is sponsored by: Ecamm: Powerful live streaming platform for Mac. Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: All Creatures Great and Small (PBS) Jason: A Knight of the Seven Kingdoms (HBO Max) Get Downstream+ and don't miss a segment! Submit Feedback Can Larry and David Ellison's Oracle Money Buy Hollywood? How Netflix's Sony Deal Explains Its Warners Pursuit - Puck

In this encore episode, we detail connections between H. pylori and hypochlorhydria, while highlighting possible downstream effects on nutrient absorption. We examine how reduced gastric acidity can impair the liberation and assimilation of certain micronutrients, including iron, calcium, vitamin B12, and more; and we further discuss the impact of low stomach acid upon downstream digestive enzyme activation and gut microbial balance. Topics:1. Hypochlorhydria - Low stomach acid.2. H. pylori 3. Gastric Anatomy & Layers- The stomach: hollow, muscular organ for mechanical and chemical digestion.- Regions: Cardia, fundus, body, and pylorus.- Layers: Mucosa, Submucosa, Muscularis externa, Serosa4. Mucosal Layer - Surface mucous cells secrete a thick bicarbonate-rich, protective mucus.- Gastric pits lead to gastric glands, which contain specialized secretory cells.5. Specialized Gastric Cells- Parietal Cells: Secrete hydrochloric acid (HCl) and intrinsic factor (IF).- Chief Cells: Secrete pepsinogen (converted to pepsin by HCl) and gastric lipase.- Role of HCl: Activates pepsin, denatures proteins, and contributes to nutrient absorption.- Intrinsic factor and vitamin B12 absorption.6. Vitamin B12 Absorption- Essential for DNA synthesis, RBC formation, neurological function.- Released from food proteins by gastric acid and pepsin.- Impaired absorption.7. Role of Gastric Acid in Broader Micronutrient Absorption- Absorption of minerals.- Soluble, ionized state.- Iron: HCl aids in preventing insoluble precipitates and supports iron absorption.8. Protective Role of Gastric Acid- Acts as a line of defense against ingested pathogens.- Maintains low microbial diversity in the stomach.- Low HCl and Small Intestinal Bacterial Overgrowth.9. Symptoms of Low Stomach Acid- Bloating, early satiety, excessive belching.- Undigested food in stool, chronic constipation.- May reflect impaired enzymatic activation and digestive insufficiency.10. Conclusion- Multifactorial causes and downstream effects.- Optimal range, neither high nor low.Thank you to our episode sponsor: 1. "Longevity" with Protein, Probiotics, Bovine Colostrum, Collagen, and More. Use code CHLOE for 25% off.*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.Thanks for tuning in!Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Joe Poirot joins the conversation and we go deep on vintage slab transitions, grading risk, and the psychology of the “slab premium.” Jonathan explains how he moved major cards out of BVG holders without mailing them, including an in person handoff to SGC at Fenway, and why a newer holder can feel like a safer asset even with a downgrade. Then we zoom out to the bigger question sparked by a High Pop Professor video: is the hobby becoming a “house of slabs,” and are we still trapped in cult like grading behavior? We also hit the uncomfortable part: older high grade cards that might not hold up to today's standards. If collectors pay today's money for “imposter” high grades and later feel burned, that can shake confidence, push people out of the market, and create downstream damage. Joe breaks down why this risk depends heavily on the lane, with real differences between ultra modern gem rates, 90s inserts, and classic 80s cardboard where PSA 9 to PSA 10 gaps can feel irrational. In this part, we cover: BVG to SGC and PSA crossovers, and how to do it without mailing grails Downgrades, security, and why a newly graded holder can feel safer PSA owning SGC and Beckett and what that does to collector psychology The “same card” thought experiment and whether the holder is the product Older “imposter” high grades and how changing standards create hidden risk Why buyers getting burned could ripple downstream across the market Gradeflation, resubmission incentives, and who ends up holding the bag Why 10s matter in some lanes, and barely matter in others Follow Sports Cards Live on Apple Podcasts, Spotify, or wherever you listen Subscribe to Sports Cards Live on YouTube for full episodes and live shows Leave a rating and review to help more collectors find the show Share this episode with a collector who's chasing old 10s or debating a crossover Follow @jlee_sportscardslive on Instagram for clips and updates Take the Hobby Spectrum assessment and request your access code at TheHobbySpectrum.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Our guest this week was born in 1943, in what was then British India – modern day Pakistan. Unlike most, who have learned history through books and second-hand sources, he has witnessed first-hand a great deal of the 20th and 21st centuries. Tariq Ali founded Verso Books, the leading left-wing publishing house in Britain, as well […]

Goose visits Downstream for the first time.For Pookajutsu ♥️Catch us live every Sunday at 14:00 on ⁠https://www.youtube.com/@RPGClinic/videos⁠Blue Sky: ⁠https://bsky.app/profile/rpgclinic.bsky.social⁠Website: ⁠http://www.rpgclinic.com/⁠Wiki: ⁠https://rpgclinic.fandom.com/wiki/⁠Discord server: ⁠https://discord.com/invite/kenG3xu⁠An RPGClinic campaign promises committed storytelling and performances, professional tech, dynamic overlays, and info boxes to keep the system accessible to new viewers. Games swing between comedy and drama at the drop of a hat. There will be laughter. There will be tears. There will definitely be double-entendres.

It has been a bellicose start to 2026, with the US army kidnapping Venezuelan President Nicolas Maduro and threatening to annex Greenland, putting many more nations, including Mexico and Colombia, on high alert. On Downstream this week is investigative journalist Glenn Greenwald, who's best known for helping Edward Snowden's disclosures about the NSA's global surveillance […]

Thu, 08 Jan 2026 22:45:00 GMT http://relay.fm/downstream/110 http://relay.fm/downstream/110 Jason Snell Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. clean 4305 Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Casey Liss Links and Show Notes: Our Picks: Jason: Down Cemetery Road (Apple TV), The Pitt (HBO Max) Casey: Shoresy (Hulu) Get Downstream+ and don't miss a segment! Submit Feedback Channels — TV Everywhere Is cablecard sup

Thu, 08 Jan 2026 22:45:00 GMT http://relay.fm/downstream/110 http://relay.fm/downstream/110 I See Spreadsheets In My Future 110 Jason Snell Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. clean 4305 Jason helps guest Casey Liss figure out what his cord-cutting strategy might be. We also discuss his Callsheet app, touch on the rise of CanCon including "Heated Rivalry," and offer some very nice TV picks. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Casey Liss Links and Show Notes: Our Picks: Jason: Down Cemetery Road (Apple TV), The Pitt (HBO Max) Casey: Shoresy (Hulu) Get Downstream+ and don't miss a segment! Submit Feedback Channels — TV Everywhere Is cablecard support ACTUAL

For over 4,000 years, silkworms have connected civilizations through ancient trade routes. Now, KAICO Ltd., a Japanese biotech spin-off from Kyushu University, is transforming these creatures into living bioreactors capable of producing complex recombinant proteins and vaccine antigens—without the bioreactors, expensive media, or massive water consumption of conventional platforms.Masafumi Osawa, Business Development Lead at KAICO, brings an unconventional path to biotech. Trained in cultural anthropology with fieldwork experience in Indonesia, he witnessed firsthand the healthcare disparities that drive his current mission. After years in pharmaceutical business development at Towa Pharmaceutical, he joined KAICO to help scale a technology he believes could reshape global vaccine accessibility. His cross-cultural expertise now proves invaluable as KAICO expands internationally, with active partnerships in Vietnam and Thailand and growing interest from other regions.Episode highlights:Masafumi's transition from anthropology to biotech, and how cross-cultural expertise benefits global health collaborations. (04:15)The founding story of KAICO, spun out from Kyushu University and focused on recombinant proteins and vaccine antigen production (08:45)Step-by-step overview of the silkworm baculovirus expression system, including pupae handling and bioprocessing basics. (10:28)Practical differences between silkworms, E. coli, mammalian, and insect cell culture platforms—exploring advantages and drawbacks. (13:10)Strategies KAICO uses to control silkworm variability, including SPF grade sourcing, diet, environment, and documentation for pharmaceutical acceptance. (15:08)Production scalability: a single pupa can match 100–1000 ml of insect cell culture, with major implications for cost and environmental footprint. (16:42)Downstream harvesting and purification—how KAICO extracts and processes proteins from silkworm pupae, keeping methods largely familiar to traditional systems. (19:31)Regulatory and GMP challenges of using live organisms, and KAICO's approach to satisfying authorities and ensuring product consistency. (21:43)Whether you're curious about alternative biomanufacturing methods or want a transparent look at silkworm-based protein expression from research to the clinic, this episode delivers practical insights and thoughtful discussion.Connect with Masafumi Osawa:LinkedIn: www.linkedin.com/in/masa-osawaKAICO Ltd.: www.kaicoltd.jp/enNext step:Need fast CMC guidance? → Get rapid CMC decision support hereOne bad CDMO decision can cost you two years and your Series A. If you're navigating tech transfer, CDMO selection, or IND prep, let's talk before it gets expensive. Two slots open this month.Support the show

After ‘Operation Al-Aqsa Flood' on October 7th, a specific narrative quickly emerged and pervaded the entire Western mainstream media. Namely, that unprecedented horrors were committed against the state of Israel and that whatever way it responded was justified. Any deviation from this narrative was quickly shut down. In the intervening years, the British state has […]

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the benefit of shunts in idiopathic normal-pressure hydrocephalus, how neurologists drive downstream revenue, and anticoagulant monotherapy after stroke.

Ash Sarkar and Aaron Bastani joined each other on 17th December for a special end-of-year Downstream, wrapping up the year in politics.

Norman Finkelstein is one of the west's leading anti-Zionist scholars. The son of Holocaust survivors, he has spent his life studying and critiquing Israel's assault on Palestine, decades before it became socially acceptable to do so. Yet despite having dedicated his career to it, by the day before Hamas' attack in October 2023, Norman had […]

Thu, 18 Dec 2025 00:15:00 GMT http://relay.fm/downstream/109 http://relay.fm/downstream/109 Jason Snell Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. clean 3871 Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, "Pluribus," and his top shows of the year. Guest Starring: Tim Goodman Links and Show Notes: Shows mentioned: Black Summer (Netflix), Severance (Apple TV), The Studio (Apple TV), Families Like Ours (Denmark; Netflix), Pluribus (Apple TV), The Diplomat (Netflix), The Bear (Hulu), Asura (Japan; Netflix), The American Revolution (PBS), Slow Horses (Apple TV), Adolescence (Netflix), Department Q (Netflix), Ludwig (BBC/Britbox), Nine Puzzles (Korea; Hulu), Deli Boys (Hulu), The Trunk (Korea; Netflix), Karma (Korea; Netflix), Trigger (Korea; Netflix), My Name (Korea; Netflix), Extracurricular (Korea; Netflix). Get Downstream+ and don't miss a segment! Submit Feedback Downstream #85: A Holiday Visit from Tim Goodman - Relay Stream Inte

[Cross-posted from Downstream #109 on Relay FM.] Tim Goodman pops down the chimney again to reunite with Jason and discuss the Oscars on YouTube, finding balance in the TV review game, the rise of international content, episode deconstructions, “Pluribus,” and his top shows of the year. Tim Goodman and Jason Snell.

Since Hamas launched its assault on October 7th, 2023, the group has become synonymous with evil in large parts of the Western media. Condemnation has come at the expense of critical engagement with the group's actions, objectives, and history, leaving a vacuum that has been filled with racist assumptions and conspiracy theories. Tareq Baconi is […]

Fri, 12 Dec 2025 00:00:00 GMT http://relay.fm/downstream/108 http://relay.fm/downstream/108 Jason Snell Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) clean 1693 Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: Get Downstream+ and don't miss a segment! Submit Feedback Disney Agrees to Bring Its Characters to OpenAI's Sora Videos - The New York Times Bob Iger's L

Fri, 12 Dec 2025 00:00:00 GMT http://relay.fm/downstream/108 http://relay.fm/downstream/108 Darth Vader Versus Ariel 108 Jason Snell Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) clean 1693 Bob Iger burnishes his legacy by... making a deal with OpenAI? Also, TV picks and a Listener Letter Challenge! (Downstream+ subscribers also get to hear us talk at length about the potential Netflix purchase of Warner Bros. Discovery.) This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Josef Adalian Links and Show Notes: Get Downstream+ and don't miss a segment! Submit Feedback Disney Agrees to Bring Its Characters to OpenAI's Sora Videos - The New York Times Bob Iger's Latest Legac

Did you know that the standard of Google searches has actually gotten worse over recent years? Once you think about it, it makes sense. Highly effective search means fewer searches overall. And fewer searches means less ad revenue. The financial basis of Alphabet, which is Google's parent company, is, of course, digital advertising. Which means […]

Elaine Low, Natalie Jarvey, Sean McNulty and Lesley Goldberg all gathered Friday morning for a special live episode of Ankler Agenda to break down the repercussions of potentially the most significant piece of show business news this decade: Netflix's acquisition of Warner Bros. Top-line concerns include: The thousands of lost jobs that will worsen unemployment in the industry — already at Depression-era levels Whether movie theaters can survive the “consumer-friendly” windows Netflix co-CEO Ted Sarandos referenced in a Friday call with investors Netflix's potential new arsenal: all-star showrunners (J.J. Abrams, Greg Berlanti and Chuck Lorre, to name a few) and a gaming vertical at last Downstream effects on linear syndication The future of the peerless brand HBO “Everybody is just shell-shocked,” Elaine said of the calls and texts she fielded all day. “The main reaction that I've been getting is that people are scared. People are nervous.” Learn more about your ad choices. Visit megaphone.fm/adchoices

Small homeschooling lessons today become major downstream results tomorrow. This episode encourages you to trust the long game. Show notes are at https://www.4onemore.com/337

Steve and Charlie listened to LSU AD Verge Ausberry's media availability following Lane Kiffin's introductory press conference.

Whether you love or loathe his tactics, it's hard to deny the disruptive impact that Roger Hallam has had on British politics via the activist organisations he has led, Extinction Rebellion and Just Stop Oil. He joins Ash Sarkar fresh from his latest stint in prison, where he wrote a treatise for Your Party that […]

Support for the Green party in Britain has been steadily rising for the past few decades. However, few predicted that when Zack Polanski took office as Green party leader in September, membership would surge from 70,000 to 150,000 members in a matter of months. According to the latest polling, the party's share of the vote […]

Thu, 20 Nov 2025 17:00:00 GMT http://relay.fm/downstream/107 http://relay.fm/downstream/107 Jason Snell Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. clean 3559 Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Alan Sepinwall Links and Show Notes: Good TV shows mentioned: The Pitt, Ludwig, Severance, Adolescence at the top, then: Pluribus, Slow Horses, Andor, The Studio, Hacks, The Diplomat, The Lowdown, It's Always Sunny in Philadelphia Get Downstream+ and don't miss a segment! Submit Feedback What's Alan Watching? Review: 'Blue Lights' isn't the Belfast equivalent of 'The Wire.' And that's okay. Why 'Brockmire' Was This Year's Best, Filthiest Comedy Surprise Series finale review: 'How I Met Your Mother' - 'Last Forever': How they conned us all Links to Sepinwall's episode-by-episode reviews for every show in his book, The Revolution Was Televised

Thu, 20 Nov 2025 17:00:00 GMT http://relay.fm/downstream/107 http://relay.fm/downstream/107 A Thanksgiving Visit from Alan Sepinwall 107 Jason Snell Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. clean 3559 Veteran TV critic Alan Sepinwall joins Jason to discuss the current state of TV criticism, the future of scripted TV, why streamers can't make sitcoms, the difference between recaps and reviews, and the best shows of the year. This episode of Downstream is sponsored by: Factor: Healthy, fully-prepared food delivered to your door. Use code downstream50off Guest Starring: Alan Sepinwall Links and Show Notes: Good TV shows mentioned: The Pitt, Ludwig, Severance, Adolescence at the top, then: Pluribus, Slow Horses, Andor, The Studio, Hacks, The Diplomat, The Lowdown, It's Always Sunny in Philadelphia Get Downstream+ and don't miss a segment! Submit Feedback What's Alan Watching? Review: 'Blue Lights' isn't the Belfast equivalent of 'The Wire.' And that's okay. Why 'Brockmire' Was This Year's Best, Filthiest Comedy Surprise Series finale review: 'How I Met Your Mother' - 'Last Forever': How they conned us all Links to Sepinwall's episode-by-episode reviews for every show in his book, The Revolution Was Televised

At Novara, we focus on the trends that are remaking the world and affecting our lives: technological development and automation, multipolarity, the demise of an American-led world order and the rise of China. On Downstream this week is a man whose work draws together all of these themes: former World Bank macroeconomist and leading expert […]

Investigative journalist Paul Holden has spent the last four years digging into the political machinations that brought Keir Starmer's Labour Party into office – findings that propel his powerful 2025 book, The Fraud: Keir Starmer, Labour Together and the Crisis of British Democracy. He tells Ash Sarkar about the cache of leaked emails that revealed the […]

In 1989, Francis Fukuyama, then a very young political scientist, declared that history was over. He wrote a book with the same title just a couple of years later. The Cold War had finished, the USSR had collapsed, liberal democracy and market capitalism reigned supreme, and it wasn't going to change. And yet in the […]

Fri, 31 Oct 2025 23:30:00 GMT http://relay.fm/downstream/106 http://relay.fm/downstream/106 Jason Snell Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) clean 2052 Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) This episode of Downstream is sponsored by: Claude: Get 50% off Claude Pro, including access to Claude Code. Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: Pluribus (Apple TV) Jason: Seth Meyers Corrections (YouTube) Get Downstream+ and don't miss a segment! Submit Feedback David Ellison's Paramount Doesn't Need Taylor Sheridan Netflix

Fri, 31 Oct 2025 23:30:00 GMT http://relay.fm/downstream/106 http://relay.fm/downstream/106 Strike While My Leverage Is Hot 106 Jason Snell Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) clean 2052 Taylor Sheridan signs a free agent deal with NBCU, Warner Bros. Discovery might have many interested bidders, and we answer your letters! (Downstream+ subscribers also get: Google/Disney carriage, Dancing With the Stars, Apple/F1, and Disney/Doctor Who.) This episode of Downstream is sponsored by: Claude: Get 50% off Claude Pro, including access to Claude Code. Guest Starring: Josef Adalian Links and Show Notes: TV Picks: Joe: Pluribus (Apple TV) Jason: Seth Meyers Corrections (YouTube) Get Downstream+ and don't miss a segment! Submit Feedback David Ellison's Paramount Doesn't Need Taylor Sheridan Netflix taps bank

In this Halloween-themed episode, Veronica Breckenridge from First Bite returns to discuss her eye-opening "Industrial Bio-Manufacturing Graveyard Report." Drawing from her experience scaling companies like Apple and Tesla, Veronica reveals why 80% of bio-manufacturing startups fail—and it's not because of bad science. The conversation explores critical mistakes like targeting commodity markets too early, underestimating downstream processing costs, and the "build it and they will come" mentality that has buried promising ventures. Veronica explains why now is actually the best time to invest in bio-manufacturing, citing decreasing costs (3 million times cheaper in 25 years), rising consumer demand for healthier alternatives to petroleum-based products, and increased government support for domestic manufacturing. She shares tactical advice on patient capital structures, the importance of strategic partnerships over going solo, and why bio-manufacturing is more analogous to hardware scaling than pharmaceutical development. The episode offers valuable lessons for founders, investors, and anyone interested in the future of sustainable manufacturing.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:(00:00:00) - Halloween intro and SNL's Snack Homies discussion(00:04:17) - Zombie apocalypse: Could fungi or viruses cause real zombies?(00:09:12) - Beyond Meat stock surge and meme trading(00:11:34) - Introducing the Graveyard Report and Veronica Breckenridge(00:14:23) - Why Veronica moved from Tesla to bio-manufacturing(00:19:45) - The three recurring market fit errors killing startups(00:27:56) - Why targeting commodity markets is a seductive trap(00:35:18) - Downstream processing: The overlooked cost killer(00:42:31) - CapEx overruns and the importance of strategic partnerships(00:48:07) - Patient capital structures for deep tech ventures(00:53:22) - What makes this moment different: Why invest now(00:58:14) - Quick fire questions and closing thoughtsLinks and Resources:First BightThe Industrial Biomanufacturing Graveyard ReportBiowell Biotech AcceleratorGinkgo ConsultingCapgeminiMcKinsey120. Busting Biotech's Bottlenecks: Veronica Breckenridge on the Path to Industrial Scale151. Report on Reports: Cash Flow, Carbon, and the BioeconomyZombie-like effects from fungusBeyond Meat's Stock SpikeTedX BostonTechnoeconomic Analysis Tool⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Topics Covered: industrial biomanufacturing, biotech, business, growth stage, graveyard report, halloweenHave a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: NihiloreProduction by: Amplafy Media

Iran has been in the news a lot in 2025. Over recent decades, it has been a variable in Iraq, Afghanistan, Syria, Lebanon, Israel, and Palestine. But during the Twelve Day War with Israel in June of this year, Iran very much took centre stage. People started asking questions, chief among them being: What does […]

The Gaza Strip, home to 2.2 million people, is a tiny land mass about the same size as the Isle of Wight. Yet in terms of munitions by weight, Gaza has been subjected to more than all of the bombs dropped on Dresden, Hamburg, and London combined, over the whole of World War II. Another […]

Just over two years after the beginning of the genocide in Gaza, and just days after the announcement of a ceasefire, Aaron Bastani spoke to three Palestinian writers in front of a live audience at EartH in Hackney. Ahmed Alnaouq is the host of Palestine Deep Dive and the co-founder of ‘We Are Not Numbers', […]

Renee Troughton: Managing Dependencies and Downstream Bottlenecks in Scrum Read the full Show Notes and search through the world's largest audio library on Agile and Scrum directly on the Scrum Master Toolbox Podcast website: http://bit.ly/SMTP_ShowNotes. "For the actual product teams, it's not a problem for them... It's more the downstream teams that aren't the product teams, that are still dependencies... They just don't see that work until, hey, we urgently need this." Renee brings a dual-edged challenge from her current work with dozens of teams across multiple business lines. While quarterly planning happens at a high level, small downstream teams—middleware, AI, data, and even non-technical teams like legal—are not considered in the planning process. These teams experience unexpected work floods with dramatic peaks and troughs throughout the quarter. The product teams are comfortable with ambiguity and incremental delivery, but downstream service teams don't see work coming until it arrives urgently. Through a coaching conversation, Renee and Vasco explore multiple experimental approaches: top-to-bottom stack ranking of initiatives, holding excess capacity based on historical patterns, shared code ownership where downstream teams advise rather than execute changes, and using Theory of Constraints to manage flow into bottleneck teams. They discuss how lack of discovery work compounds the problem, as teams "just start working" without identifying all players who need involvement. The solution requires balancing multiple strategies while maintaining an experimentation mindset, recognizing that complex systems require sensing our way toward solutions rather than predicting them. Self-reflection Question: Are you actively managing the flow of work to prevent downstream bottlenecks, or are you allowing your "downstream teams" to be repeatedly overwhelmed by last-minute urgent requests? [The Scrum Master Toolbox Podcast Recommends]

Artificial intelligence is set to be one of the most disruptive technologies this century. For some, a machine capable of augmenting its own intelligence is a matter of time — and could even arrive within a decade. This week's guest is philosopher and author William MacAskill. One of the leading thinkers in the Effective Altruism […]