The EMJ Podcast: Insights For Healthcare Professionals

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The EMJ Podcast is an educational and informative podcast which aims to provoke conversations with stakeholders in the healthcare industry. This includes talking about the latest trends and innovations, interviewing thought leaders within the world of hea

EMJ


    • Aug 6, 2025 LATEST EPISODE
    • weekdays NEW EPISODES
    • 29m AVG DURATION
    • 517 EPISODES


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    Latest episodes from The EMJ Podcast: Insights For Healthcare Professionals

    Onc Now: Episode 23: From Lab to Life in Breast Cancer Care

    Play Episode Listen Later Aug 6, 2025 35:38


    In this episode of Onc Now, host Jonathan Sackier is joined by Simon Lord, Associate Professor in Experimental Cancer Therapeutics, University of Oxford, UK, to discuss translating scientific breakthroughs into real-world treatments. With deep expertise in precision medicine and a passion for innovation in oncology, Lord brings a unique perspective on how the future of cancer therapy is being shaped today.      Timestamps  01:04 – Quickfire question  11:26 – Metabolic imaging  15:26 – Insulin resistance  18:04 – Patient-specific biology  20:35 – Tamoxifen risks  21:57 – Metabolic interventions  24:46 – Lifestyle changes  27:04 – Clinical trials  00:00 – Wishes for healthcare 

    Current Trends of Methotrexate Therapy – Do You Know it All?

    Play Episode Listen Later Aug 5, 2025 28:59


    Unmasking the Unrelenting Cough: Refractory Chronic Cough Through Patient and Practitioner Eyes.

    Play Episode Listen Later Aug 5, 2025 28:34


    The Pain–Anxiety Connection: Exploring the Neurobiology

    Play Episode Listen Later Aug 4, 2025 24:09


    In this series, host Catherine Glass speaks with David Cosio about  the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.  Timestamps: 1:07 - Background  2:10 - Day to Day  3:21 - Why Pain Management  6:06 - Conversations About Pain  7:54 - Key Neurobiological Mechanisms  9:50 - Genetics  11:02 - Brain Mechanisms  11:32 - Biomarkers 

    The Pain–Anxiety Connection: Quickfire

    Play Episode Listen Later Aug 4, 2025 5:55


    In this series, host Catherine Glass speaks with David Cosio about  the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond. 

    Unpacking Rare Lung Diseases: Pulmonary Arterial Hypertension: Deep Dive 2

    Play Episode Listen Later Jul 31, 2025 15:23


    In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research. Timestamps: 01:05 – Diagnostic workflows 03:58 – Non-invasive tools 05:37 – Right heart catheterisation values 09:05 – Vasoreactivity testing 11:10 – Genetic testing 13:08 – Innovative diagnostics

    Unpacking Rare Lung Diseases: Pulmonary Arterial Hypertension: Deep Dive 3

    Play Episode Listen Later Jul 31, 2025 20:21


    In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research. Tinestamps: 00:45 – PAH management 03:05 – Hypoxia 06:42 – Decompensated PAH 10:06 – At-home treatments 12:44 – Multidisciplinary teams 14:50 – Novel therapies

    Onc Now: Episode 22: Prostate Cancer, Lifestyle, and Equity

    Play Episode Listen Later Jul 30, 2025 37:44


    In this episode of Onc Now, host Jonathan Sackier is joined by Stephen Freedland, Surgical Oncologist at Cedars-Sinai Medical Center, Los Angeles, California, USA, to discuss the intersections of biology, behaviour, and bias in prostate cancer. From diet and exercise to disparities in outcomes and promising data on enzalutamide, Freedland challenges assumptions and advocates for a more holistic, equitable approach to care.  Timestamps   01:20 – Background and clinical journey 02:39 – Cancer myths: what needs busting 03:22 – Lifestyle's role in prostate cancer 05:18 – One habit all cancer patients should adopt 06:39 – Yes or No round 10:30 – Diet, obesity, and exercise: the data 13:25 – Mediterranean diet and outcomes 15:30 – Predictive lifestyle factors 16:19 – Racial disparities and root causes 18:35 – Gender-affirming treatment and prostate cancer in trans women 23:20 – Enzalutamide: latest data and developments 25:51 – Broader therapeutic landscape 28:40 – Risk of recurrence 30:19 – Advice for young oncologists 34:00 – Three wishes for the future of prostate cancer care 

    Unpacking Rare Lung Diseases: Pulmonary Arterial Hypertension: Deep Dive 1

    Play Episode Listen Later Jul 29, 2025 12:51


    In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research.  Timestamps:   Part 1:   01:00 – What is PAH  02:34 – Risk factors  04:21 – Misdiagnoses  07:13 – Pathophysiology  10:44 – World Symposium classification 

    Unpacking Rare Lung Diseases: Pulmonary Arterial Hypertension: Quickfire

    Play Episode Listen Later Jul 29, 2025 5:04


    In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research. 

    Unpacking Rare Lung Diseases: Alpha-1 Antitrypsin Deficiency: Deep Dive 2

    Play Episode Listen Later Jul 24, 2025 7:32


    In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care. Timestamps: 1:20 - Current barriers to timely diagnosis 4:35 - How close are we to identifying all patients with Alpha 1? 5:20 - Role of consumer genomics in alpha detection 6:20 – Targeted testing amongst COPD patients

    Unpacking Rare Lung Diseases: Alpha-1 Antitrypsin Deficiency: Deep Dive 3

    Play Episode Listen Later Jul 24, 2025 12:47


    In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care. Timestamps: 01:00 - Management of Alpha 1 03:30 - Augmentation therapy 05:50 - The discussion of neonatal screening for Alpha 1 08:00 - Evolving landscape 09:40 - Patients' challenges with Alpha 1 11:20 - Closing comments on Alpha 1

    Hema Now: Episode 22: The State of Sickle Cell

    Play Episode Listen Later Jul 23, 2025 31:40


    In this episode, host Jonathan Sackier is joined by Steven Okoli, Honorary Senior Clinical Lecturer at Imperial College London. From leading the UK's first adult stem cell transplant trial for sickle cell disease to driving innovation in AI-guided transfusion strategies, Okoli shares how clinical research, patient advocacy, and equity-driven care are reshaping the landscape of haemoglobinopathies in the UK and beyond.  Timestamps  00:00: Introduction  01:58: Quickfire round  09:09: Pioneering adult stem cell transplant in sickle cell  11:41: Combining AI and genetics for blood transfusion  13:58: Systemic disparities in sickle cell  20:58: Education and advocacy  23:30: Non-cancerous blood disorders  25:18: What's next in sickle cell?  27:27: Okoli's three wishes for healthcare  

    Unpacking Rare Lung Diseases: Alpha-1 Antitrypsin Deficiency: Quickfire

    Play Episode Listen Later Jul 22, 2025 4:20


    In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care.

    Unpacking Rare Lung Diseases: Alpha-1 Antitrypsin Deficiency: Deep Dive 1

    Play Episode Listen Later Jul 22, 2025 7:26


    In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care. Timestamps 00:56 – What is Alpha-1 antitrypsin deficiency? 01:45 – Mechanism of this genetic disorder 03:12 – What makes Alpha 1 so hard to spot? 04:30 – Genetic complexities of Alpha 1 06:00 – Risk factors  

    Onc Now: Episode 21: Redesigning Cancer Care Through Precision Medicine

    Play Episode Listen Later Jul 18, 2025 34:55


    In this episode of Onc Now, host Jonathan Sackier is joined by Jean Abraham, Professor of Precision Breast Cancer Medicine at the University of Cambridge, to delve into the future of integrated cancer medicine, the evolving role of clinical trials, and how precision oncology is redefining outcomes for patients with breast cancer across the UK.  Timestamps  00:00 – Introduction  01:28 – Quickfire round  09:50 – Cambridge institutes for precision medicine  12:53 – Predictive/prognostic tools in breast cancer  15:33 – The future of breast cancer clinical trials  18:34 – Integrating genomic data  22:31 – Addressing cost barriers  24:22 – How AI is transforming breast cancer care  28:08 – Why oncology?  30:04 – A message to non-oncologists  31:54 – Abraham's three wishes for healthcare  

    Hema Now: Episode 21 The Global Perspectives on Myeloma

    Play Episode Listen Later Jul 11, 2025 32:58


    In this episode, Jonathan Sackier welcomes Claudio Cerchione, haematologist and researcher at the Hematology Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy. From his early interest in plasma cell disorders, Cerchione shares key insights into the evolution of multiple myeloma (MM) research, the rising role of minimal residual disease (MRD), and promising developments in monoclonal antibodies and CAR-T therapy. He also reflects on standout moments from recent European Hematology Association (EHA) Congress and American Society of Clinical Oncology (ASCO) Annual Meeting, and shares his hopes for the future of haematology.   Timestamps: 2:14: Memorable career experiences for Claudio   4:20 Biggest breakthrough in MM  5:10 Interest in plasma cell disorders  6:30 A surprising fact about multiple myeloma  7:40 Claudio's top choice for a dinner party guest  10:30 The importance of MRD in haematology  13:00 Monoclonal antibodies and CAR-T therapies  19:00 Current challenges  22:22 Claudio's key EHA and ASCO takeaways  28:30 Claudio's three magic wishes  

    From Fractures to Futures: Deep Dive Part 2

    Play Episode Listen Later Jul 10, 2025 7:22


    In this three-part series, Jonathan Sackier sits down with Professor Zoë Paskins to explore the complexities and advancements in rheumatology and bone health. From her personal journey into the field to innovations in managing osteoporosis and arthritis, Zoë offers compelling insights into the current landscape and future of musculoskeletal care.   Timestamps: 0:25 - What's new in osteoporosis management? 5:05 - Key challenges in addressing gaps in care

    From Fractures to Futures: Deep Dive Part 1

    Play Episode Listen Later Jul 10, 2025 15:19


    In this three-part series, Jonathan Sackier sits down with Professor Zoë Paskins to explore the complexities and advancements in rheumatology and bone health. From her personal journey into the field, to innovations in managing osteoporosis and arthritis, Zoë offers compelling insights into the current landscape and future of musculoskeletal care. Timestamps:     00:00 - Introduction 03:45 - Zoë's start in rheumatology and what keeps her passionate 06:27 - Shared decision-making in rheumatology 12:30 - How should we be screening for osteoporosis?

    Hema Now: Episode 20: The Science Behind Myelodysplastic Syndromes

    Play Episode Listen Later Jul 4, 2025 41:51


    In this episode of Hema Now, host Jonathan Sackier is joined by Kevin Rouault-Pierre and Onima Chowdhury, to explore the biological mechanisms behind MDS, with a spotlight on SF3B1 mutations. From epigenetic stress to diagnostic strategies, this discussion bridges laboratory research and frontline care.  Timestamps 01:11 – Quickfire Round 07:11 – Haematology Misconceptions  10:56 – Understanding MDS 18:42 – Treating Myeloid Malignancies 23:20 – Epigenetic Mechanisms 28:30 – MDS Treatment Approaches 34:56 – Three Wishes 

    Environmental Health in Urology: Deep Dive Part 2

    Play Episode Listen Later Jul 3, 2025 16:33


    Plant-Based Diets In this series, the host Catherine Glass welcomes Stacy Loeb, a renowned urologist and lifestyle medicine advocate, to explore the growing impact of environmental factors on men's health. From the risks of microplastics and the benefits of plant-based diets to the carbon cost of prostate procedures, these conversations challenge conventional clinical perspectives and offer practical, planet-conscious solutions for modern urology. 0:19 – The connection between diet and health 4:05 – Organic versus non-organic: does it matter? 4:56 – Plant-based diets and improved erectile function 7:19 – Stigma and undertreatment in men's health 9:14 – Research from the Prostate Cancer Foundation 11:57 – The growing role of lifestyle medicine 14:49 – Glucagon-like peptide-1 (GLP-1) agonists in urological health  

    Environmental Health in Urology: Deep Dive Part 3

    Play Episode Listen Later Jul 3, 2025 14:32


    Carbon Emissions in Medicine In this series, the host Catherine Glass welcomes Stacy Loeb, a renowned urologist and lifestyle medicine advocate, to explore the growing impact of environmental factors on men's health. From the risks of microplastics and the benefits of plant-based diets to the carbon cost of prostate procedures, these conversations challenge conventional clinical perspectives and offer practical, planet-conscious solutions for modern urology. Timestamps:    0:30 – The carbon footprint of patient travel 2:05 – How climate change affects urological health 5:46 – Practical advice for urologists 7:53 – MRI-targeted prostate biopsies 10:40 – Emissions associated with MRI procedures 

    Podcast 1 Episode 2: Showcasing Becker Muscular Dystrophy: Exploring the Patient Experience

    Play Episode Listen Later Jul 2, 2025 26:43


    This episode offers insights into the lived experience of patients with Becker Muscular Dystrophy (BMD). Mike Voto, a patient advocate for BMD, shares his story and discusses the personal challenges around diagnosis, disease progression and the impact of living with BMD.

    Environmental Health in Urology: Deep Dive Part 1

    Play Episode Listen Later Jun 30, 2025 12:15


    Microplastics In this series, the host Catherine Glass welcomes Stacy Loeb, a renowned urologist and lifestyle medicine advocate, to explore the growing impact of environmental factors on men's health. From the risks of microplastics and the benefits of plant-based diets to the carbon cost of prostate procedures, these conversations challenge conventional clinical perspectives and offer practical, planet-conscious solutions for modern urology. Timestamps:   1:01 – Getting into urology 1:52 – Pioneering environmental health in urology 2:28 – Patient perspectives on plastic exposure 4:25 – Microplastics in testicular tissue 7:06 – Plastics are everywhere 9:30 – Immune response to microplastics 10:20 – Microplastics in female genitalia and sanitary product  

    Environmental Health in Urology: Quickfire

    Play Episode Listen Later Jun 30, 2025 5:44


    In this series, the host Catherine Glass welcomes Stacy Loeb, a renowned urologist and lifestyle medicine advocate, to explore the growing impact of environmental factors on men's health. From the risks of microplastics and the benefits of plant-based diets to the carbon cost of prostate procedures, these conversations challenge conventional clinical perspectives and offer practical, planet-conscious solutions for modern urology.  

    From Adolescents to Adults: Conversation with the Experts on HPV Vaccination

    Play Episode Listen Later Jun 27, 2025 10:47


    Breaking Barriers in Lung Cancer: Precision in Staging and Surgery

    Play Episode Listen Later Jun 26, 2025 47:10


    In the third episode of our lung cancer miniseries, Jonathan Sackier is joined by Douglas E. Wood, Henry N. Harkins Professor and Chair of Surgery at the University of Washington. A global leader in thoracic oncology, Wood explores the critical role of lung cancer staging, the evolution of screening guidelines, and how surgical innovation is shaping the future of lung cancer treatment. Timestamps: 00:00 – Introduction 02:37 – Career beginnings 07:37 – Career highlights 11:38 – Thoracic oncology guidelines 15:26 – AI and big data 17:17 – Expanding lung cancer screening 19:29 – Robotic surgery 23:38 – Targeted therapies 27:23 – Cancer staging 30:44 – Lung volume reduction surgery 35:10 – Current trials 40:50 – Three wishes for healthcare

    Patient-Centric Care Through Same-Day Discharge (SDD) - Ep 3

    Play Episode Listen Later Jun 25, 2025 14:18


    Patient-Centric Care Through Same-Day Discharge (SDD) - Ep 2

    Play Episode Listen Later Jun 25, 2025 8:49


    Patient-Centric Care Through Same-Day Discharge (SDD) - Ep 1

    Play Episode Listen Later Jun 25, 2025 12:44


    Onc Now: Episode 20: How Cancer Vaccines Are Changing Medicine

    Play Episode Listen Later Jun 25, 2025 35:42


    In this special episode of Onc Now, host Jonathan Sackier is joined by Lennard Lee, Associate Professor of Cancer Vaccines at the University of Oxford, to explore the promise of personalised cancer vaccines, the power of data science and AI in cancer care, and the national initiatives bringing these innovations to patients. Timestamps 02:01 – Quickfire intro 07:21 – COVID Cancer Programme 11:32 – Cancer vaccine potential 15:56 – Vaccine trial insights 16:58 – Data science and AI 24:10 – Positivity in practice 26:48 – Public health innovation 29:11 – Vaccine hesitancy 33:56 – Final takeaway

    Bridging Borders in Women's Health: Deep Dive Part 2

    Play Episode Listen Later Jun 20, 2025 14:07


    Innovations in the treatment of endometriosis and adenomyosis In this episode, the host Saranya Ravindran speaks with Tommaso Falcone about transformative developments in reproductive health, including the evolution of endometriosis research, the promise of robotic surgery, and the global expansion of gynaecologic care. From debunking myths about fertility to reflecting on cross-continental medical practice, this episode explores the future of women's health through the eyes of a pioneering clinician and researcher. Timestamps: 00:00 – Barriers to early endometriosis detection 09:16 – Treating adenomyosis and fertility impact 12:10 – Global health innovation in emerging markets 16:05 – The first uterus transplant

    Bridging Borders in Women's Health: Deep Dive Part 3

    Play Episode Listen Later Jun 20, 2025 21:40


    Robotic revolution in reproductive surgery. In this episode, the host Saranya Ravindran speaks with Tommaso Falcone about transformative developments in reproductive health, including the evolution of endometriosis research, the promise of robotic surgery, and the global expansion of gynaecologic care. From debunking myths about fertility to reflecting on cross-continental medical practice, this episode explores the future of women's health through the eyes of a pioneering clinician and researcher. Timestamps: 00:20 – What's next in gynaecologic robotic surgery? 06:46 – Falcone's pioneering research 16:44 – Three wishes for healthcare

    Hema Now: Episode 19: Insights and Innovations in B Cell Disorders

    Play Episode Listen Later Jun 19, 2025 29:38


    Lydia Scarfò is a Physician Scientist at the B-cell Neoplasia Unit and an Assistant Professor at Università Vita-Salute San Raffaele, Milan, Italy.   She is involved in both clinical and pre-clinical studies, including being a co-investigator in over 20 clinical trials in haematological malignancies, including chronic lymphocytic leukaemia.  Timestamps:  0:00 – Introduction  1:14 – Quickfire questions  7:31 – Haematology inspiration  9:08 – STIL loss  11:42 – Splenic marginal zone lymphoma  13:03 – Novel targeted therapies for chronic lymphocytic leukaemia  17:35 – Covalent BTK inhibitors   19:30 – Chemo-free approach for hairy cell leukaemia  22:20 – Recent advances, challenges, and opportunities  25:58 – Three wishes 

    Bridging Borders in Women's Health: Deep Dive Part 1

    Play Episode Listen Later Jun 18, 2025 14:07


    Global Perspectives and Leadership in Gynaecology In this episode, the host Saranya Ravindran speaks with Tommaso Falcone about transformative developments in reproductive health, including the evolution of endometriosis research, the promise of robotic surgery, and the global expansion of gynaecologic care. From debunking myths about fertility to reflecting on cross-continental medical practice, this episode explores the future of women's health through the eyes of a pioneering clinician and researcher. Timestamps: 00:00 – Comparing gynaecology globally 03:20 – The evolution of endometriosis research 05:30 – Breakthroughs and hopes for a cure

    Bridging Borders in Women's Health: Quickfire

    Play Episode Listen Later Jun 18, 2025 6:34


    In this episode, the host Saranya Ravindran speaks with Tommaso Falcone about transformative developments in reproductive health, including the evolution of endometriosis research, the promise of robotic surgery, and the global expansion of gynaecologic care. From debunking myths about fertility to reflecting on cross-continental medical practice, this episode explores the future of women's health through the eyes of a pioneering clinician and researcher. Timestamps: 00:00 – Introduction 01:05 – Quickfire round 05:12 – ‘Yes or no' segment

    Podcast 1 Episode 1: Showcasing Becker Muscular Dystrophy: Overview of Diagnosis, Management, and Care

    Play Episode Listen Later Jun 12, 2025 22:09


    This episode offers expert insights Dr. Aravindhan Veerapandiyan, MD. Exploring Becker Muscular Dystrophy (BMD), covering early signs, diagnostic challenges, disease progression, and current management approaches. It also explores care transitions, multidisciplinary involvement, and unmet needs in the BMD care landscape.

    Breaking Barriers in Lung Cancer: Leveraging AI and Big Data in Clinical Care

    Play Episode Listen Later Jun 12, 2025 56:20


    In this second episode of our lung cancer miniseries, Jonathan Sackier is joined by David Baldwin, a leading expert in screening, epidemiology, and policy. Baldwin reflects on national screening programmes, groundbreaking trials, and how AI, big data, and evidence-based guidelines are reshaping lung cancer care. Timestamps: 00:00 – Introduction 03:17 – Key takeaways from the UKLS trial 11:10 – Boosting participation in screening studies 17:04 – The Targeted Lung Health Check programme 23:30 – Understanding large datasets in lung cancer epidemiology 32:44 – AI and big data in lung cancer imaging 41:43 – Shaping national guidelines 47:47 – Are we doing enough to prevent lung cancer? 53:06 – Baldwin's three wishes for healthcare

    Onc Now: Episode 19: Part 2 – Key Insights from SGO 2025

    Play Episode Listen Later Jun 10, 2025 27:13


    In the second part of this special episode of Onc Now, Jonathan Sackier continues his thrilling conversation with Bradley Monk, a leading gynaecologic oncologist, with an in-depth discussion of the DUO-E trial, Monk's most impactful Society of Gynecologic Oncology (SGO) insights, and the integration of AI into the clinic. Timestamps:  00:00 – Introduction  00:40 – Quickfire questions  06:19 – Inspiration  08:31 – Molecular basis of cancer treatment  12:12 – DUO-E trial design  14:12 – Barriers to 4-drug regimen approval and access  20:01 – Most impactful SGO insights  21:10 – AI integration  24:03 – Three wishes  26:30 – Outro 

    Infectious Disease Diagnostics: The New Era of STD Screening

    Play Episode Listen Later Jun 5, 2025 46:27


    In the third and final episode of our miniseries on infectious disease diagnostics, Jonathan sits down with global diagnostics leader Rosanna Peeling, Professor and Chair of Diagnostics Research at the London School of Hygiene and Tropical Medicine. Together, they explore the life-saving role of diagnostics in global health, from battling STDs to confronting COVID-19, and examine how equitable access, social innovation, and regulatory reform can transform disease control and pandemic preparedness.   Timestamps: 00:00 – Introduction 06:09 – Rosanna's interest in microbiology 08:12 – The IDC's work 10:52 – Funding for diagnostics 13:30 – Diagnostic testing in low-resource settings 18:21 – Chlamydia research 24:19 – Regulatory approval challenges 29:35 – Social innovation 34:08 – Clinician adaptation 37:10 – Current diagnostic innovations 40:30 – Rosana's three wishes for healthcare

    Hema Now: Episode 18: Myeloma Genetics, CAR-T, and Emerging Immunotherapies

    Play Episode Listen Later Jun 4, 2025 29:54


    Rafael Fonseca is a distinguished Haematologist at Mayo Clinic, specialising in multiple myeloma and related plasma cell disorders. He earned his medical degree at Universidad Anáhuac in Mexico, and went on to complete his residency in Internal Medicine at the University of Miami, Florida, USA followed by a Hematology and Oncology fellowship at Mayo Clinic in Rochester, Minnesota, USA.     Timestamps  01:44 – Quickfire questions  07:25 – CAR-T cell therapy  10:48 – Anti-CD38 antibodies  13:31 – Minimal residual disease  14:30 – Bispecific antibodies  15:31 – Antibody-drug conjugates  19:04 – ASCO 2025  21:24 – Genetic discoveries  26:28 – Fonseca's three wishes 

    Breaking Barriers in Lung Cancer: Driving Change Through Early Screening

    Play Episode Listen Later May 29, 2025 46:09


    In this episode, Jonathan Sackier kicks off a special miniseries on lung cancer with Haval Balata, Consultant Respiratory Physician at Manchester University NHS Foundation Trust. From the Manchester Lung Health Check to robotic bronchoscopy, Balata shares insights into pioneering early detection efforts, the challenge of public misconceptions, and innovations reshaping lung cancer screening and diagnosis. Timestamps: 03:12 – Inspiration to specialise 04:09 – Early diagnosis barriers 08:02 – Manchester Lung Health Check 14:10 – Robot-assisted bronchoscopy 19:24 – Public misconceptions 28:57 – Risk stratification & follow-up 34:24 – Innovations in early detection 37:10 – Hopes for the future 41:22 – Three healthcare wishes

    Onc Now: Episode 18: What's New from ESGO 2025?

    Play Episode Listen Later May 28, 2025 18:50


    In this two-part series host Jonathan Sackier is joined by Bradley Monk, a pioneering figure in gynaecologic oncology. In Part 1, they discuss key updates from the European Society of Gynaecological Oncology (ESGO) Congress, including the updated ESGO-ESTRO-ESP endometrial cancer guidelines and the latest results from the KEYLYNK-001 study in ovarian cancer. With reflections from his three-decade career, Monk provides actionable takeaways for clinicians and researchers alike. Stay tuned for Part 2, where they delve into insights from SGO 2025.  Timestamps:  00:00 - Quickfire questions 04:55 - Career milestones 07:10 - ESGO 2025 standout sessions 09:52 - KEYLYNK-001 trial & takeaways 13:52 - New endometrial cancer staging   

    Bonus Episode: The clinician's perspective on new intermittent catheterisation technology

    Play Episode Listen Later May 27, 2025 34:05


    In this bonus episode, join EMJ host Dr Hannah Moir as she speaks with our two urological experts, Dr Todd Linsenmeyer and Dr Chris Harding. They discuss recent advances in day-to-day technologies for intermittent catheterisation, covering innovations and advancements in catheter technology aimed at improving the user experience.

    Transforming Rheumatology Part 3: Testing Misconceptions and Future Vision

    Play Episode Listen Later May 23, 2025 17:28


    In this three-part series, Jonathan Sackier sits down with Isabelle Amigues, rheumatologist and founder of UnabridgedMD, a direct rheumatology practice in Denver, Colorado, USA. Together, they discuss the importance of hope in patient care and the inspiration behind starting her own practice. Timestamps: 1:12 – A typical consultation 7:50 – Advice for clinicians

    Transforming Rheumatology Part 2: The Art of Connection and Building Patient Trust

    Play Episode Listen Later May 23, 2025 14:16


    In this three-part series, Jonathan Sackier sits down with Isabelle Amigues, rheumatologist and founder of UnabridgedMD, a direct rheumatology practice in Denver, Colorado, USA. Together, they discuss the importance of hope in patient care and the inspiration behind starting her own practice. Timestamps: 0:14 – The power of hope for patients 1:08 – Opening her own practice  

    Transforming Rheumatology Part 1: Blending Science and Soul

    Play Episode Listen Later May 23, 2025 14:07


    In this three-part series, Jonathan Sackier sits down with Isabelle Amigues, rheumatologist and founder of UnabridgedMD, a direct rheumatology practice in Denver, Colorado, USA. Together, they discuss the importance of hope in patient care and the inspiration behind starting her own practice. Timestamp: 2:27 – The origins of ‘Hope Driven by Science'

    Hema Now: Episode 17: What Drives Change in Leukaemia Cells?

    Play Episode Listen Later May 22, 2025 35:01


    In this episode of Hema Now, host Jonathan Sackier is joined by Paolo Gallipoli, Clinical Reader at the Centre for Haemato-Oncology at Barts Cancer Institute, to break down the biology, onset, and treatment of myeloid leukaemias. They detail common misconceptions about myeloid leukaemias, explain the differences between chronic myeloid leukaemia and acute myeloid leukaemia, and discuss Gallipoli's own research in the field, with a view towards future developments.  Timestamps  01:34 – Quickfire questions  06:55 – Potential careers  08:43 – Common misconceptions  11:34 – Best advice received  13:43 – Adaptive metabolic changes  16:45 – Chronic myeloid leukaemia vs acute myeloid leukaemia  19:20 – Recent publication  22:55 – Clonal hematopoiesis    27:13 – Treatment obstacles  29:18 – Future developments  31:01 – Gallipoli's three wishes 

    Clinical Insights in Rheumatology 3/3: Hospital Mortality, JAK Inhibitors, and the Future of Rheumatology

    Play Episode Listen Later May 15, 2025 18:53


    In this three-part series, Jonathan Sackier sits down with Richard Conway, rheumatologist, researcher, and educator. Together, they delve into cutting-edge insights on polymyalgia rheumatica, immune ageing, and the future of rheumatology care. 01:47 – Interstitial Lung Disease 08:25 – Evolution of Rheumatology 11:39 – Wishes for Healthcare

    Clinical Insights in Rheumatology 1/3: Teaching, PMR Clinics, and Giant Cell Arteritis Insights

    Play Episode Listen Later May 15, 2025 13:55


    In this three-part series, Jonathan Sackier sits down with Richard Conway, rheumatologist, researcher, and educator. Together, they delve into cutting-edge insights on polymyalgia rheumatica, immune ageing, and the future of rheumatology care 01:49 – Polymyalgia Rheumatica 05:59 – Vascular Ultrasound 09:11 – Immune Ageing

    Clinical Insights in Rheumatology 2/3: Diagnosis, Immune Ageing, and Rheumatology Research

    Play Episode Listen Later May 15, 2025 18:13


    In this three-part series, Jonathan Sackier sits down with Richard Conway, rheumatologist, researcher, and educator. Together, they delve into cutting-edge insights on polymyalgia rheumatica, immune ageing, and the future of rheumatology care. 00:22 – Mortality Patterns 08:57 – JAK Inhibitors

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