The EMJ Podcast is an educational and informative podcast which aims to provoke conversations with stakeholders in the healthcare industry. This includes talking about the latest trends and innovations, interviewing thought leaders within the world of hea
Sharonne N. Hayes joins host Saranya Ravindran to discuss how cardiovascular disease presents differently in women. From pregnancy-related complications and menopause to microvascular disease and gaps in clinician education, this episode explores the importance of sex-specific cardiovascular care. Timestamps: 1:04 – Sex-specific differences 2:43 – Pregnancy and preeclampsia 4:38 – Historic underdiagnosis 7:00 – Menopause and hormones 10:04 – Education and training
In this rapid-fire episode, Sharonne N. Hayes answers key questions on women's cardiovascular health, SCAD, unconscious bias, prevention, and the future of equitable heart care. A concise, expert-led overview of the field.
In the final episode, Bryan Tucker explores the future of kidney stone prevention and treatment. From genetics and microbiome research to wearable hydration technology and AI-driven risk prediction, this episode examines how personalised medicine could transform nephrolithiasis care over the next decade. Timestamps: 01:01 – Future changes in kidney stone care 04:21 – Microbiome and stone risk 05:34 – AI-driven risk prediction 07:02 – Ideal future of care
In Part 2, Bryan Tucker discusses the balance between acute intervention and long-term prevention in kidney stone care. Learn why many patients never receive comprehensive metabolic evaluation, how healthcare systems prioritise procedures over prevention, and what changes are needed to improve recurrence prevention. Timestamps: 01:05 – Intervention and long-term prevention 04:01 – Gaps in follow-up evaluations 06:57 – Care changes for better prevention
This podcast has been funded by an educational grant from Viatris. Systemic lupus erythematosus (SLE) is a complex, heterogeneous disease shaped by dysregulated immune pathways, variable organ involvement, and substantial patient burden. In this educational podcast, Anca Askanase explores how a deeper understanding of SLE immunology can help rheumatologists contextualize disease activity, evolving research, and guideline-based care. Topics covered: Key immune pathways involved in SLE pathophysiology, including innate and adaptive immune dysregulation How pathway biology may help explain clinical heterogeneity and differences in disease activity between patients What rheumatologists should consider when interpreting emerging pathway-based research and cross-disease immunology concepts How current guideline-based care frames treatment goals, patient burden, and the evolving focus on remission in SLE Speakers Anca D. Askanase, Chair, Department of Medicine, and Chief, Division of Rheumatology, Hospital for Special Surgery, New York, USA
Bryan Tucker joins host Catherine Glass to explore why kidney stone disease is becoming increasingly common worldwide. From dietary and metabolic drivers to male predominance and prevention strategies, this episode examines how nephrolithiasis reflects broader shifts in metabolic health and lifestyle. Timestamps: 01:13 – Increased prevalence 03:19 – Metabolic issues 04:30 – Increased prevalence in men 06:50 – Population-level prevention strategies 08:24 – Cardiometabolic syndrome
In this rapid-fire episode, Bryan Tucker answers key questions about kidney stone disease, from common myths and overlooked risk factors to hydration, prevention, and emerging technologies. Perfect for listeners short on time but looking for expert insights into the future of nephrolithiasis care.
In the final episode, Naveed Sattar explores the future of cardiometabolic medicine, from novel therapies and AI-driven risk prediction to integrated care pathways and the next generation of preventative strategies for diabetes and cardiovascular disease. Timestamps: 0:56 – Novel interventions 2:10 – Digital health and AI 4:17 – Integrated care 5:26 – Future directions 7:11 – Naveed's prediction
In Part 2, Naveed Sattar discusses obesity, ectopic fat, and cardiovascular risk. Learn how imaging and biomarkers are improving risk identification, why metabolic dysfunction matters beyond BMI, and how GLP-1 therapies are reshaping obesity and cardiovascular care. Timestamps: 0:56 – Ectopic fat 11:44 – Metabolic dysfunction 13:42 – GLP-1 receptor agonists 19:05 – Mechanistic insights 21:31 – Societal issues
Naveed Sattar joins host Catherine Glass to explore the complex relationship between diabetes and cardiovascular disease. From hyperglycaemia and inflammation to diabetes onset age and risk prediction, this episode examines the mechanisms and evidence shaping cardiometabolic care today. Timestamps: 0:55 – Diabetes to heart disease 4:35 – Age of onset 6:21 – Statins 09:01 – Epidemiological insights 12:29 – Improving risk prediction
In this rapid-fire episode, Naveed Sattar answers key questions on diabetes, cardiovascular disease, obesity, prevention, and emerging therapies. From precision medicine and GLP-1 receptor agonists to lifestyle interventions and research advice, this concise episode provides expert insight into the future of cardiometabolic medicine.
In the final episode, the focus turns to prevention. Rachel Buckley examines whether Alzheimer's strategies should be sex-specific, the timing of interventions, and how lifestyle factors like physical activity contribute to brain resilience. The discussion also highlights gaps in research and the need for better integration of women's health data. Timestamps: 00:00:45:13 – Sex-disaggregated data for prevention 00:03:26:15 – Sex-specific timing for therapeutics 00:05:07:20 – Non-pharmacological interventions 00:07:58:02 – Gaps in reproductive data
This episode explores how reproductive ageing and biological sex influence Alzheimer's disease risk. Rachel Buckley discusses menopause, hormonal changes, genetic factors such as the X chromosome, and emerging evidence showing differences in tau accumulation between women and men. Timestamps: 00:00:55:03 – Menopause and Alzheimer's disease 00:04:51:11 – X chromosome in Alzheimer's disease 00:08:29:01 – Tau accumulation in women 00:10:43:09 – Hormone replacement therapy 00:14:22:24 – The sweet spot with hormone therapy
In this first deep dive, Rachel Buckley joins host Catherine Glass to explore how Alzheimer's disease risk can be detected before symptoms appear. From blood-based biomarkers like p-tau217, to AI-driven models of cognitive resilience, the episode examines how risk, progression, and protection can be better understood and predicted over time. Timestamps: 00:00:57:11 – Phosphorylated tau and amyloid-PET 00:08:15:05 – Biomarkers, risk, and progression 00:11:18:04 – Brain resistance and cognitive resilience 00:15:23:23 – AI biases
In this rapid-fire episode, Rachel Buckley answers key questions on Alzheimer's disease, covering sex differences in risk, early predictors of progression, brain resilience, and the most actionable prevention strategies. A concise overview of the evolving science behind personalised Alzheimer's care.
In the final episode, host Saranya and Helen Brough examine the key gaps in allergy care across prevention, diagnosis, and long-term management, and how these challenges impact families in practice. It explores barriers to early peanut introduction, highlights inequalities in allergy care and the populations most affected, and looks at how digital tools, education, and outreach could help improve access to evidence-based care. Timestamps: 00:43 – Gaps in allergy care 04:07 – Early peanut introduction 06:39 - Disparities in diagnosis 08:12 – Improve access to care
In Part 2, we explore the role of the skin barrier in food allergy development, from how environmental allergen exposure can drive sensitisation to whether early skincare can help prevent disease. Drawing on studies such as SEAL and recent European eczema guidelines, it also tackles common misconceptions and parental concerns, including topical steroid withdrawal and how best to provide reassurance. Timestamps: 00:54:02 – Skin allergen exposure 03:50 – Optimising the skin barrier 06:46 – Proactive treatment of atopic eczema 08:17 – Applying treatments 11:41 – Topical steroid withdrawal
Helen Brough joins the Saranya to reflect on her work in paediatric food allergy, from personal experiences that shaped her career to landmark studies like LEAP, EAT, and ProNuts that transformed prevention and management. This episode explores early allergen introduction, evolving approaches to treatment, and what's driving the rise in food allergies in children. Timestamps: 00:53 – Raising children with atopy 02:18 – Antibiotic exposure at birth 03:08 – Prevention of peanut allergies 05:22 – Introducing other allergens 08:09 – Multi-nut/sesame allergy 10:41 – Immunotherapy for severe allergies 13:36 – Prevalence of food allergies
In this short rapid-fire episode, Helen Brough answers key questions on food allergy, covering common triggers, peanut allergy myths, early allergen introduction, and whether allergies can be outgrown. It also touches on immune development, common mistakes, biomarkers, and future breakthroughs.
Description: Meghan Azad discusses the challenges of translating microbiome science into public health strategies. From policy gaps to social inequalities, this episode explores how evidence can be turned into meaningful support for families. Timestamps: 02:20 – Critical windows 04:50 – Health inequalities 07:30 – Policy interventions 10:10 – Future directions
This episode examines how infant nutrition influences microbiome development and links to asthma risk. Azad discusses key discoveries from cohort studies and the role of early-life exposures in shaping disease trajectories. Timestamps: 02:40 – Microbiome development 05:10 – Asthma risk link 07:50 – Feeding transitions 10:20 – Clinical counselling
Azad explores the biological complexity of human milk and its role in shaping infant immunity. From immune-active components to variation in milk composition, this episode examines how early nutrition programs long-term health outcomes. Timestamps: 02:30 – Milk composition explained 05:20 – Immune components role 08:10 – Variation in milk 10:40 – Growth and outcomes
In this rapid-fire episode, Azad addresses common myths around breastfeeding, microbiome development, and infant feeding practices. A concise overview of the key factors shaping early immune health.
In the final episode, Pranav Garimella explores glomerular and cystic kidney diseases, including IgA nephropathy and autosomal dominant polycystic kidney disease. Discover how personalised medicine, biomarkers, and earlier diagnosis are shaping the future of care in these complex conditions. Timestamps: 01:11 – Current treatment for IgA nephropathy 02:24 – SGLT2 inhibitors 03:38 – Cystic kidney disease diagnosis
In Part 2, Pranav Garimella discusses major advances in diabetic kidney disease management. Learn how sodium-glucose cotransporter 2 (SGLT2) inhibitors and novel therapies are reshaping disease progression, and why early intervention is critical to improving long-term outcomes. Timestamps: 01:07 – Practice-changing developments 05:10 – GLP-1 agonists 07:00 – Early intervention 08:43 – Unmet needs
Pranav Garimella joins host Catherine Glass to explore why early detection of chronic kidney disease remains challenging. From high-risk populations to emerging plasma and urine biomarkers, this episode examines how earlier diagnosis and improved risk stratification can transform patient outcomes. Timestamps: 00:59 – Challenges of early detection 05:12 – Populations for intensive screening 09:08 – Plasma and urine biomarkers 13:45 – Biomarker-driven risk stratification
In this rapid-fire episode, Pranav Garimella answers key questions on chronic kidney disease, from early detection and screening challenges to future innovations in nephrology. A concise overview for clinicians and curious listeners alike.
In the final episode, Nanette K. Wenger discusses the ongoing challenges in awareness and access to cardiovascular care for women. From public health campaigns to mentorship and community initiatives, discover what's needed to close the gap. Timestamps: 1:02 – Barriers in care 2:54 – Future directions 6:11 – Atlanta Women's Network
In Part 2, Nanette K. Wenger examines how underrepresentation in research shaped cardiovascular epidemiology in women. Learn about the impact of key guideline developments, and where critical data gaps remain. Timestamps: 1:09 – Historical underrepresentation 5:05 – Evidence gaps
Nanette K. Wenger joins host Saranya Ravindran to reflect on her pioneering work in women's cardiovascular health. From challenging early misconceptions to advocating for inclusion in research, this episode explores how the field began to shift. Timestamps: 0:58 – Nanette's inspiration 5:21 – Dismantling misconceptions 8:12 – Research obstacles 14:20 – Risk factors
In this rapid-fire episode, Nanette K. Wenger answers key questions on women's heart health - from prevention and lifestyle to mentorship, research gaps, and the future of cardiology. A concise, expert-led overview of the field.
In this episode of Onc Now, Christopher Wolfgang shares insights into the evolving landscape of pancreatic cancer research and treatment. From his early inspiration in oncology to pioneering surgical approaches and tackling tumour recurrence, Wolfgang discusses the challenges that persist in this complex disease space and the innovations shaping its future. Timestamps: 00:00 – Introduction 01:28 - Career inspiration 03:24 – Impact of early training 05:00 - Advances in treatment 09:20 - Tumour recurrence research 11:25 - Surgical innovation impact 17:00 - Barriers to progress 20:24 - Future priorities 26:40 - Three healthcare wishes
Gupta examines disparities in food allergy and asthma outcomes, highlighting barriers to care and the role of policy, research, and innovation in improving health equity. Timestamps: 01:00 – Racial and socioeconomic barriers 03:37 – Collaborations to reduce disparities 05:05 – Emerging therapies 10:08 – Future care
From early allergen introduction to digital health tools, Gupta discusses modern prevention strategies and how clinicians balance prevention with long-term management in food allergy care. Timestamps: 00:51 – Key messages for families and clinicians 02:56 – Allergies and breast milk 04:17 – Ongoing allergies 06:50 – Allergy education 10:34 – Telemedicine and digital tools 11:45 – Mentoring
In this rapid-fire episode, Ruchi S. Gupta answers key questions about food allergy misconceptions, prevention strategies, and asthma care. A concise overview for clinicians looking to stay updated in minutes.
Ruchi S. Gupta explores how food allergy and asthma care have evolved over the past 2 decades, from guideline development to school-based programmes and early prevention strategies shaping paediatric care. Timestamps: 00: 55 – Recent care evolution 04:12 – Primary care management 06:00 – Schools and community programmes 09:13 – Prevention strategies
In the final episode, Majid Fotuhi explores how purpose, social connection, and brain networks influence longevity and dementia risk. Learn how cultivating meaning in life can support cognitive health and long-term brain resilience. Timestamps: 01:03 – Brain regions 02:19 – Dementia risk 02:42 – Role of clinicians 04:42 – Social connection 07:00 – Dr Fotuhi's book
In Part 2, Majid Fotuhi explains how stress and inflammation accelerate brain ageing. Discover the role of sleep in clearing toxins, the benefits of neurofeedback, and which brain training strategies truly enhance cognition. Timestamps: 01:14 – Stress and inflammation 04:40 – Importance of sleep 08:16 – Benefits of neurofeedback 10:19 – Brain training 12:20 – Concussion and ADHD
In this episode of Hema Now, Robert Negrin, President of the American Society of Hematology (ASH), reflects on his distinguished career in stem cell transplantation and cellular therapy, and shares his vision for the future of the field. From shaping global haematology priorities to advancing innovative treatments such as CAR-T cell therapy, he explores both the remarkable progress and the ongoing challenges facing clinicians and researchers today. The conversation also highlights the importance of translational research, mentorship, and collaboration in driving meaningful improvements in patient care, while looking ahead to the technologies and breakthroughs that could redefine haematology in the years to come. Timestamps: 00:00 - Introduction 01:20 - Presidency priorities, mission advancement 05:45 - Evolving global haematology needs 08:17 - Career inspiration, key developments 16:13 - Cellular therapy opportunities, challenges 19:47 - Translational research importance 22:22 - Future of stem transplantation 26:08 - Mentorship principles, trainee guidance 29:45 - Emerging technologies impact 30:40 - Three wishes, haematology future
Majid Fotuhi joins host Saranya Ravindran to explore how nutrition influences brain ageing. From anti-inflammatory diets and omega-3s to insulin resistance and metabolic health, this episode unpacks how what we eat shapes cognition and long-term brain resilience. Timestamps: 01:10 – Mediterranean Diet 02:58 – Reducing Alzheimer's risk 03:37 – Dietary changes 05:44 – Metabolic dysfunction 08:00 – Exercise and Sleep
In this rapid-fire episode, Majid Fotuhi answers key questions on brain ageing - from memory-boosting habits and diet to stress, neurogenesis, and Alzheimer's risk. Perfect for a quick, science-backed overview of how to protect your brain.
This content has been funded by AstraZeneca, and is intended for healthcare professionals. The content in this podcast is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment, nor to promote any specific product or therapy. The guests have been compensated by AstraZeneca for their participation. The views expressed are their own and do not necessarily reflect those of the AMJ or AstraZeneca. If you choose to act on information discussed here, you do so at your own discretion. Description: As homologous recombination deficiency (HRD) testing becomes increasingly embedded in ovarian cancer pathways, clinicians need clear, operational guidance. This episode brings together expert perspectives on selecting tests, understanding outputs, and integrating results into guideline-aligned care. Learn: · HRD basics in plain language: what you're measuring and why · Test selection and reporting nuances that affect downstream decisions · Workflow design across oncology, pathology, and genetics · Applying results to maintenance strategies and patient conversations Speakers: 1. Rebecca Arend, Associate Director for Clinical Research, UAB O'Neal Comprehensive Cancer Center; Endowed Professor of Gynecologic Oncology, University of Alabama, USA. 2. Thomas Krivak, Director, Division of Gynecologic Oncology; Chief Surgeon, West Penn Hospital, USA. 3. Bhavana Pothuri, Gynecologic Oncologist, NYU Langone Health; Associate Professor, Department of Obstetrics and Gynecology, NYU Grossman School of Medicine, USA.
Järvinen-Seppo discusses how translational research is advancing understanding of early allergic disease, from maternal antibodies to global collaborations shaping the future of prevention and care. Timestamps: 00:57 – Research scope 03:49 – Maternal antibodies 07:34 – Integrating new evidence 09:17 – International coordination 10:37 – Emerging areas
This episode examines the spectrum of food allergy, from IgE-mediated disease to food protein induced enterocolitis syndrome and eosinophilic conditions, and explores how diet, skin barrier function, and the microbiome interact in early life. Timestamps: 00:53 – Spectrum of allergic diseases 05:00 – Nutrition and immune activation 07:22 – Atopic dermatitis 08:55 – IgE-mediated food allergy 10:28 – Future management pathways
In this episode of Onc Now, Claire Snyder explores the growing importance of patient-reported outcomes and quality of life in modern oncology care. She discusses the challenges and opportunities of integrating patient perspectives into routine practice, as well as the global effort to standardise these measures through initiatives such as the PROTEUS Consortium. The conversation also highlights the evolving needs of survivors of cancer, key priorities in survivorship care, and what the future holds for patient-centred oncology. Timestamps: 00:00 – Introduction 01:41 – Modern oncology care 03:56 – Patient-reported outcomes (PRO) interest origin 05:10 - PRO implementation challenges 06:36 - PROTEUS Consortium mission 08:33 - Survivorship care priorities 09:45 - Childhood survivor insights 12:35 - Advice for newcomers 13:37 - Future quality of life developments 14:41 - Three wishes
Kirsi Järvinen-Seppo explores how the infant immune system develops, highlighting the role of maternal environment, breast milk composition, and early-life exposures in shaping allergy risk. Timestamps: 00:57 – Infant immune system 02:06 – Maternal lifestyle factors 06:10 – Breast milk composition 10:13 – ESCAPE study 13:25 – Early sensitisation pathways 16:58 – Early risk stratification
In this rapid-fire episode, Kirsi Järvinen-Seppo tackles key questions on infant immune development, common misconceptions around food allergy, and the early-life factors that shape allergic disease. She also highlights emerging research on maternal influences, breast milk immunology, and prevention strategies that could transform clinical practice.
In the final deep dive, Cherry Lim looks ahead to the future of AMR surveillance. She discusses the role of microbiology labs, the value of imperfect datasets, and how integrating genomics, modelling, and cost-effectiveness could transform global health systems over the next two decades. Timestamps 00:00 – Introduction 01:03 – Investing in diagnostics 02:36 – Routine surveillance data 03:53 – Global versus local AMR data 05:08 – Future health systems
In this second deep dive episode, Cherry Lim discusses how complex modelling approaches can translate into practical clinical insights. From counterfactual frameworks to real-world prescribing decisions, she explores how data-driven tools can support clinicians in choosing more effective antibiotic treatments. Timestamps 00:00 – Introduction 01:03 – Understanding counterfactual frameworks 02:56 – Antibiotic choice and survival 05:08 – Clinical decision dashboards 06:24 – Assumptions in AMR modelling
In this episode of Hema Now, Marilyn Manco-Johnson explores the evolution and future of paediatric haemophilia care. From the early adoption of prophylactic treatment to today's rapidly advancing therapeutic landscape, she reflects on the milestones that have transformed outcomes for children. The conversation also dives into ongoing challenges, including joint health, variability in treatment response, and access to care, while highlighting emerging innovations such as gene therapy and non-factor therapies that could redefine long-term management. Timestamps: 00:00 – Introduction 00:49 - Career inspiration 04:40 - Prophylaxis turning points 09:41 - Key care advances 12:12 - Current research questions 15:00 - Joint risk factors 19:10 - Emerging therapies impact 24:24 – Recognising joint pain 26:08 - Gaps in care 29:11 - Future priorities
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