Podcasts about methyl

This episode originally aired as #327 on 5/20/23. It's an oldie but goodie so we are sharing it again! Mental Health is a mounting issue in America today.  Pharma prescriptions are higher than ever before, more people are in therapy than ever before and more than ever, people are searching for alternatives to those methods. On today's episode Jared runs through what he considers to be the foundational things that you should consider to improve your mental health. You will learn about the gut brain connection, deficiencies that impact mental health, the value of breath, sleep, water,  sunshine and more.Products:Precision Probiotic Vital SporesVital 5 Magnesium BisglycinateVital 5 Ultimate Vitality Multi-VitaminBioCoenzymated Active B ComplexVital 5 Omega 3 + AntioxidantsUltra Strength RX Omega 3Sensoril AshwagandhaAnxiety ReleaseVital SleepL-Theanine chewables Additional Information:Episode #164: Psychobiotics - Unique Probiotics for Depression, Anxiety and More Part 1Episode #166: Psychobiotics - Unique Probiotics for Depression Anxiety and More Part 2Episode #306: The Great Debate in Probiotics: Human Strains vs. SporesEpisode #258: Your Magnesium Users GuideEpisode #264: Jen's Story: How One Woman Fought Through Addiction, Mental and Physical Illness to Find Vitality.Episode #265: Sleep! Your Guide to Falling Asleep, Staying Asleep and Deeper and More Restful SleepVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

 There is a cheap and easy lab test that can give you a lot of information about your risk for scary things like  heart attack, stroke, dementia, brain shrinkage, osteoporosis and more. It could save your life.  But most doctors won't order it unless you ask them to because they don't know what to do with the results.  But you're about to.  Let's talk about homocysteine.come to my website: www.healthcouragecollective.comemail me: healthcouragecollective@gmail.com

The results of a new study shows that consumption of polyphenols in certain foods--known as methyl adaptogens--can turn back your biological clock. Listen in this week as Dee discusses the study and reveals the short list of common foods that literally help you age better from the inside out.Reference: Villanueva, J. L., Vita, A. A., Zwickey, H., Fitzgerald, K., Hodges, R., Zimmerman, B., & Bradley, R. (2025). Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study. Aging. https://doi.org/10.18632/aging.206240

This Real Science Exchange podcast episode was recorded during a webinar from Balchem's Real Science Lecture Series. You can find it at balchem.com/realscience.Feeding rumen-protected choline in early lactation has consistently increased milk yield and energy-corrected milk yield, which is more pronounced when cows are fed diets low in metabolizable methionine. Choline feeding also increases milk fat and protein yield, minimizes body condition loss in early lactation, and reduces postpartum disease incidence. Dr. McFadden presents three topics about choline biology in the dairy cow. (01:45)Why should we consider fatty acid feeding when feeding methyl donors like choline and methionine?Choline degradation in the rumen and small intestine, focusing on the role of triethylamine oxide Why should we consider lysophosphatidylcholine as an immunomodulator in fresh cows and preweaning calves?Fatty acid nutrition to optimize methyl donor efficiency. (4:02)Fatty liver is a concern for fresh cows because of its relationship with ketosis, poor fertility and compromised milk production. Cows with fatty liver exhibit low circulating concentrations of phosphatidylcholine, which is a component of very low-density lipoproteins (VLDL) that transport triglycerides out of the liver. Feeding rumen-protected choline lowers liver triglyceride deposition by supporting the synthesis of phosphatidylcholine and thus, VLDL. Dr. McFadden goes on to explain the two different pathways for phosphatidylcholine in the liver and how those interact with fatty acid metabolism. He describes several experiments that have investigated how rumen-protected choline and supplemental fatty acids interact in lactating cows. Low phosphatidylcholine supply is a key feature of fatty liver in dairy cows, likely due to low polyunsaturated fatty acid (PUFA) and low choline supplies. Delivery of post-ruminal PUFA may support phosphatidylcholine synthesis with accompanying improvements in insulin sensitivity, body condition maintenance, and inflammation, but interactions with dietary fatty acid digestibility should be considered. Dr. McFadden gives a list of considerations for fresh cow diets incorporating fat and choline supplementation. Gastrointestinal choline degradation and trimethylamine N-oxide (TMAO)  (16:58)Unprotected choline is almost totally degraded in the rumen. Microbes convert choline into trimethylamine (TMA) which is then converted to TMAO in the liver. Rumen-protected choline allows for a large proportion of choline to reach the small intestine intact. However, research shows that choline can also be degraded by microbes in the small intestine in the same pathway, limiting choline bioavailability. Plasma TMAO accumulation is associated with non-alcoholic fatty liver disease, inflammation, insulin resistance, obesity, oxidative stress, and cardiovascular disease in rodent and human models. Little research was available regarding if the relationship between TMAO and poor health was causative or just associative. Dr. McFadden's lab infused cows intravenously with TMAO and found that TMAO did not modify milk production or glucose tolerance in early lactation cows.  TMAO does not appear to influence energy metabolism or health in early lactation cows. Choline is subject to both ruminal and lower-gut degradation to TMA, and that influence on choline bioavailability needs to be defined. Data in non-ruminants suggests that unsaturated fatty acid feeding can shift the gut microbes to slow TMA formation. Lysophosphatidylcholine and immunomodulation (28:45)Dr. McFadden gives an overview of neutrophil activation and the oxidative burst that contributes to pathogen killing. The ability to elicit the oxidative burst is diminished in pre-weaned calves and transition cows. When cows were given endotoxin to cause an immune response, circulating lysophosphatidylcholine was decreased. In rodent models, lysophosphatidylcholine promotes the oxidative burst and suppresses long-term inflammation in response to bacterial infection. Dr. McFadden cultured neutrophils from pre-weaned calves with lysophosphatidylcholine and observed an enhanced oxidative burst.Immunosuppression is characterized by low circulating lysophosphatidylcholine concentrations in dairy cows. In  vitro data suggests lysophosphatidylcholine can activate neutrophils, and rumen-protected choline increases circulating lysophosphatidylcholine. Future research is likely to define an immunomodulatory role for choline. Dr. McFadden takes questions from the webinar audience. (38:07)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table.  If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.

In der Winterpause ist der größte Spaß für die Jungs vom chemischen Element, wie jedes Jahr, mit dem selbstgebauten Eisschlitten über die zugefrorenen Seen im Leipziger Umland zu heizen. Dabei geraten sie an den reichen Bauunternehmer und Vollzeit-Viertel-Sportchef Uwe Thomas und verlieren ein Rennen gegen seinen BMW. Frustriert erfahren sie von den Platzern, die gerade den Rasen, auf dem Freitag ein Heimspiel ausgetragen werden soll, mit einem Traktor durchpflügen, bei einem kleinen Grog zur Aufmunterung von ihren Abenteuern im Zweiten Weltkrieg und ihrem eigenhändig abgeschossenen amerikanischen Bomber. Der Bomber (leider kein brauchbarer Neuner) müsste immer noch im Sumpf liegen. Das chemische Element macht sich auf die Suche nach dem Motor und finden ihn schließlich. Den geborgenen Motor bauen sie in ihren Eisschlitten ein, um Uwe Thomas in der Revanche doch noch zu besiegen. Aber es kommen immer wieder Probleme auf: Der Kraftstoff hat nicht die nötige Oktanzahl und der Cospudener See ist inzwischen getaut und von Studenten besiedelt. Mittlerweile ist es Sommer und im Podcast muss wieder gemeckert werden. Bei der von Meister Jagatic wegen Tor- und Ergebnisflaute veranstalteten Grillparty für die Mannschaft, die wegen Schwierigkeiten beim illegalen Schnapsbrand zum Desaster führt, kommt das Leutzscher Leitmedium an das Rezept für einen Wundersprit: Methyl ("Medül"). Sie sind überzeugt, dass der Motor damit laufe und sie konstruieren einen neuen Renner, diesmal mit Rädern („diese schwarzen Stücken mit Luft dran, die wo man mit fahr'n tut.“ - O-Ton Jonas). Während des Baus vom skeptischen Uwe Thomas aufgehetzt, lässt sich Jonas zu einer Wette hinreißen: einen Monat kostenlos Quadriga-Mitglied gegen den Podcast. Von diversen Querelen, zuletzt dem vergessenen Nockenring, aufgehalten, verliert der Podcast-Moderator die Wette und der Baumogul fordert seinen Gewinn ein. Vom ahnungslosen Kilian handgreiflich bedroht, überredet Bastian Uwe Thomas zu einer neuen Wette: ein Jahr Handwäsche für den BMW gegen den Podcast. Aber auch diese Frist verpassen sie, so dass der Podcast in die Hände des 64-jährigen Bommelmützenbesitzers wechselt. Um ihren Podcast doch noch zu retten, dreht Nils voll auf, und mit dem methylbetriebenen Motor fahren sie zurück durch die Zeit („Ich häng jetzt die Zeit ab, jetzt.“) und erreichen gerade noch rechtzeitig die Geschäftsstelle. Das anschließende, von der Quadrige (2.0) angezettelte Rennen um den Podcast gewinnen unsere Helden dank Flugzeugmotor und Methyl mit Leichtigkeit. Der Podcast ist gerettet. Shownotes: Quadriga 2.0 in Leutzsch LVZ Artikel zur Antritts-PK der Quadriga Die PK auf YouTube Moritz Dehne wird neuer Mitarbeiter Organisation Positionspapier gegen die Handhabung der Spieltagsansetzungen MDR - Nordost-Regionalligisten kritisieren Spieltagsansetzungen Nils' Artikel zum Wirken des Hermann W. Medientipps: The Wagner Brothers | ZDF Mediathek MAMMUT - Ein Mord in meiner Familie und meiner Suche nach Antworten Dominik Kaeppeler | YouTube Contioned for Demolition - Haywire Zave it

Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions:    Chris: My heavy metals test showed elevated thallium but my water is fine. What hidden unknown foods/sources is this coming from?   Anonymous: Hello, I've tested my hormones but didn't know it should be done by a saliva test. I'm wondering if I can still make something out of the results of the female hormones I tested in this way? Or are these results completely off? They've tested FSH, LH, prolactin, estradiol, progesterone, testosterone, DHEA-S, TSH and cortisol.. I understand it is not the same as with a saliva test, but hopefully it still means something? What should I look into , to understand the levels? I know Equlife offers tests, but you don't ship here, unfortunately.. Thank you for your help     Anonymous: Hi, I've been listening to a lecture from a naturopath about folic acid & methyl folate.. apparently all the studies about it closing the neural tube of the fetus were done on folic acid, not the methylated form. It apparently only makes sense to take methyl folate if you have the MTFHR mutation, otherwise you can actually feel worse on it and better on folic acid (non methylated). I know you say methylated folate is better but I'm wondering why, if all the 4research of its efficacy for fétus development is done on no methylated folate? Thanks for the explanation     Mel: Hi Dr. Cabral - thanks for your zest for all you do! I have an undiagnosed autoimmune condition and completed your 21-day detox a few months back, which was pretty uneventful without any noticeable side effects. After the detox, I had a rough stressful patch, and my diet went off the rails. So before beginning the Para Support protocol I'd like to do, I thought doing a 7-day detox would be a good idea to make sure my body was ready to handle it. The first day of the detox, however, my body reacted differently - it felt like it was on edge and dysregulated in a sense: my neuropathy flared up in an uncomfortable way, dizziness kicked in, my muscles got sore and fatigued, and my breathing felt more labored. Why would this only happen during my 2nd detox, and what can I do to remedy it?     Patrick: Hey doc ! Huge long time fan. I'm a very active 50 year old male. I'm always either hitting the gym or playing sports about 5 days a week . Last week I didn't have time for the gym so I exercised at my house doing allot of push ups, dips and band exercises this is nothing new I do it all the time. Last week the day after doing this I now have horrible elbow pain it feels like it's getting dislocated everytime i move my arm and put any type of pressure on it at all . Any tiype of rehab you can suggest would be great thanks     Rickardo: I have had great benefits in doing your Detox quarterly. however, i have noticed that after about 5-6 days, my resting heart rate drops to low 50's (usually I am in the 70's). I have even had it reach as low as 48. Any reason as to why this is? While i am quite healthy, i am certainly no athlete. Note i do have chronic stress which i am working on improving (which has shown through cortisol levels when i tested). Is the detox / fast perhaps a little too much for me considering i have been suffering from anxiety / high stress over a prolonged period of time, and hence why heart rate decreases to low 50's? Note i did a heart test through my GP and it came back with no issues. Also note after getting off the fast, my resting heart rate eventually returns to 70's. thank you so much!!     Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3221 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

She breaks down the considerations for symptom management and potential risks, particularly regarding tumors and blood labs. In this episode of 'To Health With That,' naturopathic doctor Amy Neuzil discusses the complexities surrounding methylfolate dosing for individuals with MTHFR. High doses of methylfolate could come with some of the same risks as high-dose folic acid, so it's essential to find the right dose for you without overdoing it. The three factors to consider are symptom management, potential risks, and serum folate levels. She breaks down the considerations for symptom management, potential risks, particularly regarding tumors, and blood labs. Amy also shares her own methylfolate regime and emphasizes the importance of personalized care and listening to one's body. 00:00 Introduction 00:31 Introduction to Folate Toxicity 01:25 Considerations for Methylfolate Dosing 01:56 Symptom Management 02:27 Risks of High Folate Doses 02:42 Blood Testing Guidelines 03:40 Personal Methylfolate Regime 05:34 Importance of Personalized Care

MTHFR Gene and The Importance of Methyl B12 and Methyl Folate Vitamin B12 identified as a potential therapeutic agent in the prevention and treatment of acute pancreatitis A life Well Lived Dr. Ellsworth Wareham https://www.georgebatista.com Green Vibrance: vibrance.georgebatista.com Wellness Resource: myvitaminresource.com Protonmail: Protonmail.georgebatista.com rumble.georgebatista.com Email: Wellnesstalk@protonmail.com

Welcome to The Daily Wrap Up, a concise show dedicated to bringing you the most relevant independent news, as we see it, from the last 24 hours (10/25/24). As always, take the information discussed in the video below and research it for yourself, and come to your own conclusions. Anyone telling you what the truth is, or claiming they have the answer, is likely leading you astray, for one reason or another. Stay Vigilant.  !function(r,u,m,b,l,e){r._Rumble=b,r[b]||(r[b]=function(){(r[b]._=r[b]._||[]).push(arguments);if(r[b]._.length==1){l=u.createElement(m),e=u.getElementsByTagName(m)[0],l.async=1,l.src="https://rumble.com/embedJS/u2q643"+(arguments[1].video?'.'+arguments[1].video:'')+"/?url="+encodeURIComponent(location.href)+"&args="+encodeURIComponent(JSON.stringify([].slice.apply(arguments))),e.parentNode.insertBefore(l,e)}})}(window, document, "script", "Rumble");   Rumble("play", {"video":"v5hvbn9","div":"rumble_v5hvbn9"}); Video Source Links (In Chronological Order): (24) Diana Panchenko

In this episode of Egg Meets Sperm, Dr. Aumatma, a Naturopathic Doctor and Fertility Specialist, breaks down one of the most debated topics in prenatal health: folic acid vs. methyl tetrahydrofolate (5MTHF). For over a decade, there's been an ongoing discussion about whether synthetic folic acid or the more bioavailable form, 5MTHF, is better for preventing neural tube defects and supporting a healthy pregnancy.Dr. Aumatma explains the science behind folate metabolism, the critical role it plays in fertility, and why many women might benefit from switching to 5MTHF. Learn how the MTHFR gene mutation impacts folate conversion and why up to 80% of the population may struggle to properly process folic acid.Key Topics Covered:The differences between folic acid and 5MTHFHow folate prevents neural tube defectsThe role of MTHFR mutations in folate metabolismWhy 5MTHF may be a better choice for pregnant womenHow much folate you should take during pregnancyDr Aumatma is;A licensed Naturopathic Doctor for 15 years, additional board certification in Naturopathic EndocrinologyCreator of The Restorative Fertility MethodHost of Egg Meets Sperm Podcast, a Top 5% podcast2x Best-selling author: Fertility Secrets and (in)Fertility: Struggles, Secrets, & SuccessesAwards: Best Naturopathic Medicine Doctor (2015, 2020) and Top Women in Medicine Doctor (2020, 2021), Berkeley Hall of Fame (2022)Interviewed on 100+ podcasts about fertility, pregnancy, and postpartumFeatured as the Holistic Fertility Expert on ABC, FOX, CBS, KTLA, MindBodyGreen, The Bump Has trained hundreds of practitioners around the world in holistic approaches to fertility, and has certified top doctors in the Fertile Foundations™ system Founder of Madre Fertility, with a free Smart Fertility Analysis, to help you better understand blocks to fertility, and create a customized roadmap for the journey.Medical Advisor for Mira Fertility, Element, and Feminade - three awesome leaders in fertility & women's health Don't miss this in-depth discussion to understand how choosing the right form of folate can impact your fertility and pregnancy. Let's chat! I want to hear from you! Send me a voice memo with:- what you loved- what you want to see improve- any guests you want me to bring on- AND any questions you want me to cover on the podcast!Did you know you can join my private community to support you in getting Fertile As F***? This is the place for live interactions, support, and learning on the fertility journey.Want more amazing content? Join me on IG.If you found this podcast episode useful, we'd love it if you can take 15 seconds to give us a positive review on whichever platform you're listening to this episode.

Hey poison pals! This one is a bit longer than usual, so bear with us (beer with us?). We are tackling alcohol (ethanol vs methyl alcohol) and the Prohibition of the 1920s/30s in the US. Alcohol is a toxin and we can't not discuss its effects on the body and on culture as well as the effects of methyl/wood alcohol which blinded and killed many during the Prohibition. Also, come learn how the American government was involved in the poisoning of its citizens during this time (seriously big oops). Obviously, the making and drinking of alcoholic beverages was going on way before that time period, so of course we delve into some world alcohol history and such first! You'll notice a pause halfway through where we took a break to get through the day (and I return with a well earned drink of my own--just one, because moderation and all that). Anyway, come learn and have fun with us as we delve into this messy business. Thanks so much to everyone for listening and supporting us however you can! We love to hear from you guys on here and on the IG! Support us on Patreon: patreon.com/thepoisonersalmanac Follow us on socials: The Poisoner's Almanac on IG- ⁠https://www.instagram.com/poisoners_almanac?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==⁠ Adam- ⁠https://www.tiktok.com/@studiesshow?is_from_webapp=1&sender_device=pc⁠ Becca- ⁠https://www.tiktok.com/@yobec0?is_from_webapp=1&sender_device=pc⁠ --- Support this podcast: https://podcasters.spotify.com/pod/show/goldstar002/support

TWiM explains unique modifications in the energy conservation pathways linked to methanogenesis in an Archaeon, and mechanisms of white nose fungal invasion of cells from the Little Brown Bat. Hosts: Vincent Racaniello, Michael Schmidt, Petra Levin and Michele Swanson. Become a patron of TWiM. Links for this episode Methyl-reducing methanogenesis (Nature) Pathogenic strategies of Pseudogymnoascus destructans (Science) Adaptive fungal invasion of bat cells (Science) Little brown bat (Critter Catalog) Nature Notes: Little Brown Bat (Harpswell) Take the TWiM Listener survey! Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

John Incledon, President and CEO of Hisamitsu America, the makers of Salonpas, has seen enormous growth in the acceptance of over-the-counter topical pain management options since introducing the Salonpas analgesic patch in the US market 37 years ago. This growth is partly due to television ads featuring doctors touting the benefits of Salonpas for mild to moderate nerve-related and muscle-related pain and the sampling program that aims to get doctors and patients to try out the products.   John explains, "Topical medications have only been around since the 1960s, with the introduction of the first OTC monograph by the FDA. Salonpas itself was formally introduced to the United States in 1987, so we've been around some 37 years or so as a brand in this country. And so, it's been a challenge. I'll give you a couple of fun facts: 85% of US households have a pill form of an OTC pain reliever in their house, and 30% have a topical analgesic of any sort, a cream, a roll-on, or a patch. So, there's a great disparity there. Pills remain a modality, topicals are up and coming, and I think the horizon for them is excellent." "Topicals work locally, at least OTC topical analgesics. You can wear patches and things intended to be systemic, but in this category and the products we're talking about, they're not. They're intended basically just to work below the surface of the skin. There are pain receptors that certain actives will trigger to help minimize the pain. However, they're not intended to get into the bloodstream, so by working locally and acting locally, they're generally safer than systemic analgesics."   "We have basically two mechanisms of action in our products. One is anesthetic-based and uses lidocaine, and lidocaine is going to be most appropriate to the extent that you can diagnose this if your source of pain is from aggravated nerves. So if your lower back pain is tending to move outward, say, from the spine, you want to use an anesthetic to treat that, and so, a lidocaine-based product would be best." "If it's purely muscle-related, then you're better off with our alternative formulas, which include menthol, methyl salicylate, and camphor. Methyl salicylate is an aspirin derivative, so it's categorized as a non-steroidal anti-inflammatory but topically applied, as opposed to systemically." #Salonpas #Hisamitsu #GoodMedicine #ItsGoodMedicine #PainManagement #OTC #OvertheCounterDrugs #TopicalAnalgesics us.hisamitsu Listen to the podcast here

John Incledon, President and CEO of Hisamitsu America, the makers of Salonpas, has seen enormous growth in the acceptance of over-the-counter topical pain management options since introducing the Salonpas analgesic patch in the US market 37 years ago. This growth is partly due to television ads featuring doctors touting the benefits of Salonpas for mild to moderate nerve-related and muscle-related pain and the sampling program that aims to get doctors and patients to try out the products.   John explains, "Topical medications have only been around since the 1960s, with the introduction of the first OTC monograph by the FDA. Salonpas itself was formally introduced to the United States in 1987, so we've been around some 37 years or so as a brand in this country. And so, it's been a challenge. I'll give you a couple of fun facts: 85% of US households have a pill form of an OTC pain reliever in their house, and 30% have a topical analgesic of any sort, a cream, a roll-on, or a patch. So, there's a great disparity there. Pills remain a modality, topicals are up and coming, and I think the horizon for them is excellent." "Topicals work locally, at least OTC topical analgesics. You can wear patches and things intended to be systemic, but in this category and the products we're talking about, they're not. They're intended basically just to work below the surface of the skin. There are pain receptors that certain actives will trigger to help minimize the pain. However, they're not intended to get into the bloodstream, so by working locally and acting locally, they're generally safer than systemic analgesics."   "We have basically two mechanisms of action in our products. One is anesthetic-based and uses lidocaine, and lidocaine is going to be most appropriate to the extent that you can diagnose this if your source of pain is from aggravated nerves. So if your lower back pain is tending to move outward, say, from the spine, you want to use an anesthetic to treat that, and so, a lidocaine-based product would be best." "If it's purely muscle-related, then you're better off with our alternative formulas, which include menthol, methyl salicylate, and camphor. Methyl salicylate is an aspirin derivative, so it's categorized as a non-steroidal anti-inflammatory but topically applied, as opposed to systemically." #Salonpas #Hisamitsu #GoodMedicine #ItsGoodMedicine #PainManagement #OTC #OvertheCounterDrugs #TopicalAnalgesics us.hisamitsu Download the transcript here

In this podcast, we're going to talk about eight ways to improve physical trauma. Inflammation is part of the body's healing response. You can't heal without inflammation. Inflammation is only a problem when it becomes chronic. Inflammation is the most potent carcinogen. Anything that involves chronic inflammation increases your risk for cancer. When trying to resolve physical trauma, you want to fix the chronic inflammatory state. Let's take a look at eight ways to improve physical trauma. 1. Isolate and eliminate the problem Find out if a food or habit is causing your problem. The carnivore diet or the keto diet can help eliminate issues caused by certain foods. 2. Contrast therapy Alternate between hot and cold therapy. Try a sauna, cold therapy, or hot and cold showers. This increases circulation in the lymphatic system and improves inflammation at the cellular level. 3. Exercise One of the most potent things for chronic inflammation is exercise. When you have an injured body part, there is a lack of motion in that area. Putting your body into motion may help reduce inflammation. 4. Stretching Stretching can help you sleep, improve joint health and motion, and improve posture. It can also break up scar tissue that's causing inflammation. 5. Vitamin D, omega-3 fatty acids, B3, polyphenols, methylene blue High levels of vitamin D can help remodel tissues in the body. Vitamin B3, omega-3 fatty acids, and polyphenols may help reduce inflammation. Methylene blue is one of the first synthetic medications. It can help reduce inflammation at the cellular level and helps to support the mitochondria. 6. Opposite technique Apply pressure on the opposite side of the body as your pain or trauma. 7. Fasting Fasting is a surprising way to reduce inflammation in the body. 8. Shockwave therapy This unique therapy is painless and helps target scar tissue and inflammation. Video on Methylene Blue: ▶️ • Fascinating Health Benefits of Methyl... Acupressure Playlist: ▶️ • Sciatic Nerve Pain Be Gone: Dr. Berg'... Video on niacinamide: ▶️ • The #1 Best Vitamin for Arthritis (NO...

Is aging a disease that can be cured? Neil deGrasse Tyson and cohosts Chuck Nice and Gary O'Reilly discover the field of epigenetics, the Information Theory of Aging, and curing blindness for mice with Professor of Genetics at Harvard Medical School, David Sinclair.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/is-aging-a-disease-epigenetics-with-david-sinclair/Thanks to our Patrons Jason L, Daniel Holzmann, Anne P Vance, Unknown, Myles G Blanton, Paul A. Straus, and Gregory Dees for supporting us this week.

Watch Here : https://www.youtube.com/watch?v=_8YDyBfiqs0 Website: https://vigoroussteve.com/ Consultations: https://vigoroussteve.com/consultations/ eBooks: https://vigoroussteve.com/shop/ YouTube Channel: http://www.youtube.com/user/VigorousSteve/ Workout Clips Channel: https://www.youtube.com/channel/UCWi2zZJwmQ6Mqg92FW2JbiA Instagram: https://instagram.com/vigoroussteve/ TikTok: https://www.tiktok.com/@vigoroussteve Reddit: https://www.reddit.com/r/VigorousSteve/ PodBean: https://vigoroussteve.podbean.com/ Spotify: https://open.spotify.com/show/2wR0XWY00qLq9K7tlvJ000 Patreon: https://www.patreon.com/vigoroussteve

This is part two of our three part series where we explore the intricate ways genetics intersect with ADHD. In our previous episode, we discussed how genetics influence ADHD, laying the foundation for today's discussion. If you missed last week, make sure and go back and listen to that episode, because it lays the foundation for today's.  If you have ever wondered about MTHFR or other genes that affect ADHD and ASD, tune in to today's episode to learn more. MTHFR is often regarded as the poster child of ADHD and autism, but there are many other genes that also play a role.  Here is the chart mentioned in the episode:    677CC 2 normal 677CT One variant 677TT Two variants 1298AA 2 normal 100% 66% 25% 1298AC One variant 83% 48%   1298CC Two variants 61%     Learn more about my favorite DNA test here - https://shop.adhdthriveinstitute.com/the-dna-company-360-report.html Key Takeaways: [2:45] What is Methylation? [4:15] Examples of What Methylation Does In the Body [6:23] Genes that Affect Methylation [6:55] MTHFR [13:20] SHMT1 [16:46] MTRR [18:29] MTR [20:48] FUT2   Memorable Moments: “It's not just about one gene mutation. It's about looking at the overall picture.” ”If you have a MTHFR genetic mutation, it impairs the body's ability to break down that folic acid, which may lead to a buildup of folic acid in the body. Excess folic acid can contribute to a range of health issues, including cognitive decline, mood and behavioral disorders, and potentially even increase the growth rate of cancer cells.” “So the take away that you need to write down right now is  - If you have a mutation in the MTHFR, you should not eat packaged goods that are fortified with synthetic folic acid.” ”Most people look at MTHFR in isolation and you really need to look at the methylation as a whole if you want to get a better picture of how the body is functioning. There are also other genes that play a massive role in methylation.” ”So the takeaway here is - If you have have a SHMT1 mutation, using Folinic acid instead of Methyl-folate is the better way to go.” “Understanding these genes can really help you tailor your approach to managing ADHD. It's like having a personalized roadmap to help you navigate through the ups and downs of ADHD.” “The more you know about your or your child's genes, the better choices you can make.”   Dana Kay Resources: Website: https://adhdthriveinstitute.com/  Facebook: https://www.facebook.com/ADHDThriveInstitute/  Instagram: https://www.instagram.com/adhdthriveinstitute/  YouTube: https://www.youtube.com/c/ADHDThriveInstitute  LinkedIn: https://www.linkedin.com/company/adhd-thrive-institute/mycompany/  Pinterest: https://www.pinterest.ph/adhdthriveinstitute/  Tiktok: https://www.tiktok.com/@adhd_thriveinstitute  International Best Selling Book, Thriving with ADHD – https://adhdthriveinstitute.com/book/  Free Reduce ADHD Symptoms Naturally Masterclass - https://bit.ly/3GAbFQl  ADHD Parenting Course – https://info.adhdthriveinstitute.com/parentingadhd ADHD Thrive Method 4 Kids Program – https://adhdthriveinstitute.com/packages/

Guests: Dr. Pete Hansen, University of FloridaTo conclude this mini series, Dr. Pete Hansen of the University of Florida presents on the topic of using methyl donors to regulate an early embryo and create an epigenetic effect. This talk was given at the 2022 Tri-State Dairy Nutrition Conference, and is the fourth part of this series.Beginning his presentation, Dr. Hansen highlights how nutrition can cause epigenetic reprogramming of the fetus. Methyl groups can be added to increase the pattern of DNA methylation in cells and change the phenotype. 3:55To elaborate on DNA methylation, Dr. Hansen gives the example of placenta vs. embryo cells. A micrograph of both cell types shows that placenta cells have much larger amounts of methylation than embryo cells, indicating that placenta cells are specifically programmed while methylation of embryo cells can still be influenced by the environment. 4:57Continuing on the topic of methylation, Dr. Hansen discusses how DNA methylation silences specific genes, such as in skin cells or mammary glands. The methylation in the dam can be recapitulated in offspring, representing an epigenetic pattern. 14:42Opportunities to increase DNA methylation exist. Dr. Hansen points out that altering the environment of an embryo by growing it in vitro for just seven days changes the phenotype. 23:10How can this knowledge be used to the advantage of the dairy industry?Seeking to answer this question, Dr. Hansen and his graduate students added large amounts of choline (excellent source of methyl groups) to cultured embryos. They found the addition of choline to increase triglyceride accumulation and DNA methylation. 31:45After allowing the choline-treated embryos to mature in the recipient cattle, Dr. Hansen and his colleagues found the dams to have longer gestation lengths. This likely led to the higher birth weight of the calves which persisted into weaning. While a high birth weight is not particularly beneficial, a higher weaning weight certainly can be. 36:30Finishing up his presentation, Dr. Hansen refers to the common animal science equation: phenotype = genetics + environment. He praises the dairy industry's proficiency in using genetic selection to create better offspring, but he states that improvements could be made in the environment, suggesting that more focus be placed on the prenatal environment. 41:37Please subscribe and share with your industry friends to bring more people to join us around the Real Science Exchange virtual pub table.  If you want one of our new Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll get a shirt in the mail to you.

In today's episode I'm going to be talking about the vitamin known as folate or vitamin B9. Like the seven other variations of vitamin B, vitamin B9 is used to convert food into fuel and support healthy skin, eyes, hair, and blood cells. During pregnancy, some form of vitamin B9 is needed to ensure the baby's proper brain, skull, and spinal cord development to prevent birth defects. Folate is also important for the detoxification process carried out in the liver as well as for protecting our DNA. The reason I want to cover this vitamin is because I find that there's so much confusion about it and so many of you are trying to figure out whether you need more or less folate. Also, how to navigate gene variations related to folate to make sure that you can prevent health issues that are associated with those gene variations. Folic Acid vs Folate One of the first confusions is about the difference between folic acid and folate. A lot of times you'll find that the word folic acid and folate are used as if they're the same thing when they are not. Folic acid is a man-made or synthetic nutrient, so it's not found in nature naturally occurring, whereas folate (which is also in biochemistry referred to as methyl folate METHYL) is the form that's found in nature and in our bodies. Methylfolate is active folate, which is the precise enzymatic form available for immediate cellular absorption and energy release. Although it has a similar end function to folic acid, choosing this efficient and ready-to-use form is a much more effective option for people who have difficulty converting food into fuel. Our bodies know how to use and process folate naturally. We have a certain degree of ability to turn folic acid into folate within our bodies but it's our gene variations that determine how well we can do that. Depending on your genetics you may have a 10% to 80% decreased ability to turn folic acid into folate. Folic acid is used to fortify different foods. It's a synthetic substance that's added to man-made foods. If you think of bread and cereal, you might see on the ingredient list folic acid as they're using the synthetic form. Sometimes multivitamins and B complex or prenatal vitamins or even protein shakes or other processed products might have folic acid as an ingredient. Using the synthetic form of these nutrients is oftentimes less expensive than using the natural form. The natural form called folate or methylfolate is found in all green vegetables like spinach, broccoli, asparagus, Brussels sprouts, etc. Meat products also have this natural form of the nutrient, like liver and other forms of meat. You can also find it in sunflower seeds and some forms of beans and peanuts for example. How To Measure Folate in Your Body Depending on your genes, your body may have a better or worse ability to turn folate acid into folate. If you want to know your folate levels, blood work may be misleading because they show both the synthetic and the natural form under the name folate. For a more accurate measurement of how much active folate you have in your body we need to either do a specialty test (there are labs that do specialty tests to identify your actual active folate levels) or do a test for something called homocysteine because homocysteine is a metabolite in our biochemistry that uses folate. So, if we measure the homocysteine, we can get a sense of if our bodies have enough folate, too much folate or not enough. Another way to get a sense of this is to check your methylmalonic acid because methylmalonic acid tells us your B12 metabolism and B12 levels and how well your body is using the B12. I want you to know this because I want you to know that there's people like me who have a lot of additional training to understand all this biochemistry and nutrients and can help guide you to optimize your homocysteine your methylmalonic acid and your folate and the use of folate in your body. So, I don't want you to feel like you're on your own with all of this. Folate and MTHFR MTHFR is a type of gene mutation that lowers the efficiency of the MTHFR enzyme. When you have MTHFR your body cannot properly convert folate into methylfolate. By disrupting the natural metabolic pathway, MTHFR blocks usable methylfolate from reaching the cells. Inadequate methylfolate levels can have a wide variety of negative effects on the body, particularly those that affect the cardiovascular and nervous systems. During pregnancy, a lack of methylfolate can also have serious impacts on healthy fetal development. Fortunately, there are several folate replacements available that can largely make up for deficiencies that are caused by MTHFR. Folic acid and folate can be cheap, but methylfolate tends to be the most effective option when it comes to treating the unique needs of MTHFR and giving the body an enzyme it can directly act upon. It's important to know that there are other factors affecting your body's ability to turn folate into methylfolate whether you have MTHFR or not. This is what I refer to as your stress recovery. Depending on how well your taking care of your body and helping your body recover from various stress exposures determines the influence of your genes on your health. People with MTHFR might assume that there's nothing they can do about their folate levels but there is. This depends on many factors that we will discuss today. What Affects Our Ability to Use Folate Besides Genetics? If you have a gene variation but if it's not expressing, then it is not affecting your health. But there's factors from our environment or what I refer to as stress that affect our ability to metabolize folate. Any kind of emotional or psycho-emotional stress in the present moment or even in the past or accumulated stress will influence your cortisol and adrenaline levels. When those levels get out of balance your ability to utilize folate gets hindered. Also, any kind of physical stress (whether you have an injury, infection, nutrient depletion, etc) can affect your ability to use folate effectively and it also affects your genetic expression. Those same stresses affect the enzymes that work with folate and our methylation or ability to use our B vitamins. Folate has to get together with B12 and all the all the other B vitamins and they do what's called the methylation cycle. If you want to learn more about methylation you can watch episode No 145 of How Humans Heal here. So, our ability to use our B vitamins is affected by emotional and physical stress and that's why I talk about stress recovery because it really determines your ability to optimally use folate. Also, with stress recovery you can optimize your cortisol and adrenaline and you can optimize other functions in your body so that you can really get the most out of your folate from your diet. Another important factor in how your body is able to benefit from folate is your nutrient intake and nutrient deficiencies. If you have nutrient deficiencies because you are not eating healthy or do not take any supplements to help your body with nutrients, you could have a deficiency in folate. Also, some medications like birth control pills or methotrexate (which is a medication used to treat autoimmunity), some antibiotics, metformin for blood sugar issues, anticonvulsant drugs, etc. can all cause a deficiency of folate even if you're eating enough folate. These block the metabolism of folate. If you're taking any of these medications it's important that you talk to your practitioner so you make sure that you are taking the right tests and the right form of folate.   Your ability to use folate is also affected by inflammation in the body. The main determinant of inflammation in the body is your diet. If you're consuming foods that are more inflammatory to your body, then your ability to use folate could be affected. To know which foods are inflammatory for your body you can do a food sensitivity panel. With this home test you can see which foods you need to reduce or avoid to reduce inflammation in your body. Also, if the digestion system is inflamed or if leaky gut is present there will be an imbalance in gut bacteria and this influences your ability to use folate and absorb nutrients in general. Also, exposure to toxins, toxins from our environment, food, water, home toxins like mold, heavy metals, etc. all affect our ability to adequately use folate. If you would like to know more about how to detoxify your body, you can check out my 14-Day Detox Program here. How Much Folate Do I Need? The common confusion is people will find out that they have high homocysteine levels and then they're thinking they need to take more folate. But then very often people will contact me and say but I felt worse when I took folate. Why? Well we have to dig in and figure out what's blocking your ability to use that folate effectively. When you feel worse in any way when you take folate it tells me there's a traffic jam in your stress recovery and your inflammation and your digestive health, your toxin levels, your nutrients, we got to go through systematically to figure that out and address whatever we see and as we address those factors then your body will start using folate again. It's not that you need more or less, it's about getting your body to work in the right way to absorb just the right amount from your food and your supplements. We need to break up the traffic jams that are preventing your ability to use it effectively. There is a dietary recommendation, everyone needs a certain amount of folate. The standard dietetic recommendation is 600 to 800 IU of folic acid, I convert that to methyl folate and that's the bare minimum. That's not taking into account your individuality, your individual genes your individual stress exposure and your individual imbalances. So, we need to figure out what is the right amount for you. This is why I would say it's such a high priority to fully understand your potential gene variations and understand where to get the right information so you can figure out what's the right amount of folate for you. Now, keep in mind the right amount of folate for you could change from year to year if your hormones change, if your environment changes, if your job changes, etc. That's why I think everyone should have their homocysteine levels checked in their blood work at least once a year. You may or may not know if you have a MTHFR gene variation. Either way, you can still get your blood work for homocysteine and methylmalonic acid and you can work on identifying the factors that might be decreasing your ability to use folate efficiently. You don't have to do an MTHFR gene test but if you do an MTHFR gene test what I think is important to know is that this is just one piece of information. It can be very validating to get your genes tested and to have that information but at the same time it can be overwhelming. What is more important is to identify the ways in which you can support your body to use folate efficiently like stress recovery, detoxification, reducing inflammation, food sensitivities, nutrient deficiencies, etc. The thing is we're all unique humans, we're all going to have some genetic variations and these genetic variations are not life threatening and actually have the potential to benefit your health because once we see where the genetic variations are we can address them using nutrients, diet, stress recovery, hormone balancing, etc. We can use many tools to help address those gene variations and to even potentially influence genetic expression. If you want to learn more about this you can listen to my FREE MTHFR Masterclass here. If you want to run a test not just for MTHFR but for all your genes I can guide you on which test to do for that and then I would suggest meeting with me to help guide you through that. If you're looking for products that contain methylfolate you can look in my website and online store because I have a multi vitamins and B complexes and prenatals and protein shakes that contain methylfolate so you can be sure you're getting a product that has the right form of folate in it. If you want to feel better by rebalancing your neurotransmitters, you start by addressing your cortisol and adrenaline levels with this home test kit. You can also sign up for my Stress Warrior Program here. Also, if you want to learn more about how to recover from stress so that you can get back to feeling your best, you may want to read my book Master Your Stress Reset Your Health. In the book, I also share the quiz I developed to help you identify how stress has affected you specifically by knowing your Stress Type. You can also take this Stress Type Quiz online. If you want to go through your specific case with me and improve your health (mental or physical) you can set up a one-on-one appointment here. We're here to help you! Connect with Dr. Doni:    Facebook HTTPS://FACEBOOK.COM/DRDONIWILSON   Instagram HTTPS://INSTAGRAM.COM/DRDONIWILSON   YouTube HTTPS://YOUTUBE.COM/USER/DONIWILSONND   Weekly Wellness Wisdom Newsletter: HTTPS://DOCTORDONI.COM/WWW     -   Books and Resources:    Order My New Book: https://www.amazon.com/Master-Your-Stress-Reset-Health/dp/1953295576   Stress Warrior Book (FREE)  HTTPS://DOCTORDONI.COM/STRESSWARRIOR      Stress Warrior Stress Resiliency Facebook Group (FREE)  HTTPS://FACEBOOK.COM/GROUPS/STRESSWARRIOR     7-day Stress Reset (FREE)  HTTPS://DOCTORDONI.COM/STRESS-RESET     HPV & Cervical Dysplasia Guide (FREE)  HTTPS://DOCTORDONI.COM/HPV-AND-CERVICAL-DYSPLASIA-GUIDE/     -   Personalized Solutions:    If you'd like to meet with Dr. Doni one-on-one for your health, request a Health Breakthrough Session: HTTPS://DOCTORDONI.COM/BREAKTHROUGH     To get an idea of more comprehensive options, read about Dr. Doni's Signature Consultation Programs: HTTPS://DOCTORDONI.COM/SERVICES   Disclosure: Some of the links in this post are product links and affiliate links and if you go through them to make a purchase I will earn a commission at no cost to you. Keep in mind that I link these companies and their products because of their quality and not because of the commission I receive from your purchases. The decision is yours, and whether or not you decide to buy something is completely up to you.  

Huberman Lab Key Takeaways Check Out the Huberman Lab Podcast Episode Page & Show NotesCurious about Andrew Huberman's recipe for good sleep? Read more hereRead the full notes @ podcastnotes.orgIn this episode, I discuss Methyl​enedioxy​methamphetamine (MDMA), which is also commonly known as “ecstasy” or “molly,” including how it works in the brain to cause short- and long- term-shifts in emotional processing and its clinical applications for the treatment of post-traumatic stress disorder (PTSD), alcohol and other substance-use addictions. I discuss the neuronal mechanisms for how MDMA elevates mood, empathy, motivation, social engagement, and empathy, and reduces “threat detection” and how these effects can synergistically support talk therapy. I also explain the ongoing debate about the potential neurotoxicity of MDMA, myths about the origins and treatments for post-MDMA “crash,” the evolving legal landscape around MDMA use for clinical purposes, and I caution recreational users about the extremely dangerous additives (e.g., fentanyl) now commonly found in black market MDMA. This should be of interest to those curious about MDMA, neuropharmacology, the origins of emotional processing in the brain, empathy, PTDS, neuroplasticity, mental health and psychiatry. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman Helix Sleep: https://helixsleep.com/huberman ROKA: https://roka.com/huberman HVMN: https://hvmn.com/huberman LMNT: https://drinklmnt.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) MDMA “Ecstasy” (00:04:37) Sponsors: Helix Sleep, ROKA, HVMN (00:08:18) MDMA History & Synthesis; Legality (00:14:45) MDMA, Methamphetamine (Meth), Dopamine & Serotonin (00:23:30) MDMA vs Psychedelics vs Ketamine (00:26:54) MDMA & Serotonin 1B Receptor, Subjective Feelings, Trauma (00:33:36) Sponsor: AG1 (Athletic Greens) (00:34:51) Amygdala & Threat Detection, Pro-Social Behavior, MDMA Dosages (00:45:48) Interoception, MDMA & Post-Traumatic Stress Disorder (PTSD) (00:52:36) Long-Term Effects, Threat Detection & PTSD (00:56:14) MDMA, Social Connection & Empathy; Meth, SSRIs (01:06:10) Sponsor: LMNT (01:07:22) Oxytocin & MDMA (01:16:10) Safety & Neurotoxicity; Recreational Use, Caffeine & Fentanyl (01:26:36) Is MDMA Neurotoxic?; Poly-Pharmacology, Body Temperature (01:37:07) Post-MDMA “Crash”, Prolactin & P‑5‑P (01:43:07) PTSD & Trauma; Talk Therapy, SSRIs (01:54:09) PTSD Treatment: Talk Therapy + MDMA (02:02:46) MDMA & Addiction; Dissociative PTSD & Empathy (02:09:47) Side-Effects?, MDMA Efficacy & Legality (02:15:22) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

In this episode, I discuss Methyl​enedioxy​methamphetamine (MDMA), which is also commonly known as “ecstasy” or “molly,” including how it works in the brain to cause short- and long- term-shifts in emotional processing and its clinical applications for the treatment of post-traumatic stress disorder (PTSD), alcohol and other substance-use addictions. I discuss the neuronal mechanisms for how MDMA elevates mood, empathy, motivation, social engagement, and empathy, and reduces “threat detection” and how these effects can synergistically support talk therapy. I also explain the ongoing debate about the potential neurotoxicity of MDMA, myths about the origins and treatments for post-MDMA “crash,” the evolving legal landscape around MDMA use for clinical purposes, and I caution recreational users about the extremely dangerous additives (e.g., fentanyl) now commonly found in black market MDMA. This should be of interest to those curious about MDMA, neuropharmacology, the origins of emotional processing in the brain, empathy, PTDS, neuroplasticity, mental health and psychiatry. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman Helix Sleep: https://helixsleep.com/huberman ROKA: https://roka.com/huberman HVMN: https://hvmn.com/huberman LMNT: https://drinklmnt.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) MDMA “Ecstasy” (00:04:37) Sponsors: Helix Sleep, ROKA, HVMN (00:08:18) MDMA History & Synthesis; Legality (00:14:45) MDMA, Methamphetamine (Meth), Dopamine & Serotonin (00:23:30) MDMA vs Psychedelics vs Ketamine (00:26:54) MDMA & Serotonin 1B Receptor, Subjective Feelings, Trauma (00:33:36) Sponsor: AG1 (Athletic Greens) (00:34:51) Amygdala & Threat Detection, Pro-Social Behavior, MDMA Dosages (00:45:48) Interoception, MDMA & Post-Traumatic Stress Disorder (PTSD) (00:52:36) Long-Term Effects, Threat Detection & PTSD (00:56:14) MDMA, Social Connection & Empathy; Meth, SSRIs (01:06:10) Sponsor: LMNT (01:07:22) Oxytocin & MDMA (01:16:10) Safety & Neurotoxicity; Recreational Use, Caffeine & Fentanyl (01:26:36) Is MDMA Neurotoxic?; Poly-Pharmacology, Body Temperature (01:37:07) Post-MDMA “Crash”, Prolactin & P‑5‑P (01:43:07) PTSD & Trauma; Talk Therapy, SSRIs (01:54:09) PTSD Treatment: Talk Therapy + MDMA (02:02:46) MDMA & Addiction; Dissociative PTSD & Empathy (02:09:47) Side-Effects?, MDMA Efficacy & Legality (02:15:22) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

For those of you who missed it, Jared gave a well-received talk at Be Healthy Utah on April 22nd in Utah. Many people asked for a copy of that talk, so he decided to reproduce it as a podcast. This isn't that talk, it is new, but it covers the same territory in even more detail.Mental Health is a mounting issue in America today.  Pharma prescriptions are higher than ever before, more people are in therapy than ever before and more than ever, people are searching for alternatives to those methods. In today's episode, Jared runs through what he considers to be the foundational things that you should consider to improve your mental health.  You will learn about the gut-brain connection, deficiencies that impact mental health, the value of breath, sleep, water,  sunshine, and more.Products:Precision Probiotic Vital SporesVital 5 Magnesium BisglycinateVital 5 Ultimate Vitality Multi-VitaminBioCoenzymated Active B ComplexVital 5 Omega 3 + AntioxidantsUltra Strength RX Omega 3Sensoril AshwagandhaAnxiety ReleaseVital SleepL-Theanine chewables Additional Information:Episode #164: Psychobiotics - Unique Probiotics for Depression, Anxiety and More Part 1Episode #166: Psychobiotics - Unique Probiotics for Depression Anxiety and More Part 2Episode #306: The Great Debate in Probiotics: Human Strains vs. SporesEpisode #258: Your Magnesium Users GuideEpisode #264: Jen's Story: How One Woman Fought Through Addiction, Mental and Physical Illness to Find Vitality.Episode #265: Sleep! Your Guide to Falling Asleep, Staying Asleep and Deeper and More Restful SleepTickets to the Mitten Durch Mental Health FestivalOgdenite ArticleVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

See all the Healthcasts at https://www.biobalancehealth.com/healthcast-blog If you are over 50 you have probably wished that you could have a face lift to bring you back to how you looked in your 20s or 30s. As an owner of a Medical Esthetic Spa named BioBalance Skin®, and because I am 68 myself, I have spent years looking for a facial treatment that would get the results of a surgical face lift, but without the pain, surgery and downtime. Because of the EmFace,  I have finally found what I was looking for so  I bought it!  It is called EM-Face, kin is the first medical spa to offer this treatment that makes facelifts a thing of the past. The EM Face is not only unique because the results of the EmFace are amazing, but it is also  unique because it isn't painful, it doesn't require many treatments (EMFace series is 4-6 treatments, one per week), and does not require anesthesia, there is no down time, no loss of time from work, and you are not at the mercy of a surgeon's skill to make you look like yourself at a younger age,  instead of a young stranger (think Sharon Stone). The EmFace treatment is done in our Medical Spa, and each treatment takes 30 minutes.  There is no operating room or anesthesia needed and it takes 4-6 sessions 30-minutes long , painless treatments that you don't even have to get undressed for!  After your treatment you can go right out in the world without bruising or any sign that you had a face lifting procedure. How does the EmFace work?  It uses electrical stimulation of the facial muscles to pull your facial skin up toward your temples, and it also tightens the facial skin so it literally makes your skin smooth and removes wrinkles!   Skin tone and muscle tone are improved and wrinkles disappear. …A face lift doesn't improve your skin tone and it only smooths deep wrinkles. Leaves no evidence of having a lifting procedure except that over the following 3 months you look progressively younger.   This is an advantage if you don't want your friends to know that you had anything done to make you look younger.  A face lift is obvious and it is hard to hide the fact that you had a major procedure to regain a youthful looking face. How long does it last? A Face Lift lasts about 10 years depending on the thickness and tone of your skin, as well as your age when you have the surgery.  EmFace generally requires one maintenance treatment a year to maintain the “lift” indefinitely. Cost comparison? EM-face 4 treatments costs around $2,800  and 6 treatments cost $3600 at BioBalance Skin®and that's it!. A facelift surgeon can charge t up to $100,000 for his or her services. Then  you have to add the additional costs of the operating room +  the cost of the surgical assistant + supplies and usually  you have to pay for one night in the surgery center. For a facelift, plan on paying over $150,000 total (assuming you have no complications) vs a total charge of $2,800-$3,600 for an EMSCULPT facelift.  Oh, I forgot to add the value of your time off from your job which can be 3 months after a facelift, before you want be seen  in public. Why does a face lift prevent you from showing your face right away? Facelift Surgery on the face involves dissecting the skin away from the muscle and bones of the face, pulling the skin up toward your temples, trimming off extra skin and then closing the incisions with suture. This massive dissection causes a large amount of swelling and bruising, requiring drains placed in your face, for weeks.  This damage lasts a long time and is PAINFUL! It generally causes patients to remain  housebound until they completely recover, which can be months. EMFace causes none of these side effects and complications,  so you can go out in public, or back to work right afterwards with a “glow”, and no sign that you had anything more than a facial. What are the comparable risks? The risks of a facial surgery of any kind are dramatic…damage to the facial nerve may not be recoverable, making you unable to smile or show expression on one side of your face.  Surgery risks are always numerous and most surgeries include the complications of anesthesia, even death, infection, bruising, non-healing, nerve damage scar formation and facial drooping. What should I do to prepare for either of these treatments for good results? Replace your testosterone (improves healing), and estradiol (improves texture and tone of your facial skin. Topical Skin Care, medical grade, (eg. Skinceuticals products) that stimulates the stem cells of your skin to grow and smooth the texture preparing for healing and tightening. Replace your estrogen and testosterone if you are over 45, 4- 6 months before the “lift”. Eat a high protein diet (more than half your weight in grams of protein/day) Stay hydrated with water and sometimes electrolytes. Lose as much weight as possible before the procedure. Get monthly hydra-facials and or micro-needling to prep your skin Take daily collagen supplementation in your coffee or tea Take healing vitamins: Vitamin D 5,000 u/day, Vitamin Methyl B12 and Methyl-folate, Vitamin A 10,000-25-000 u/day, Vitamin C 1000 mg/day at the very least. To help you make a decision, I have to tell you a little secret about what a facelift doesn't do.: a facelift doesn't take the place of getting  filler every 6-12 months; A facelift doesn't take the place of botox of other neurotoxin. After a face lift you will still need regular skin peels and hydrafacials, exfoliation, and rejuvenation of the face and neck with laser or micro-needling! A facelift JUST LIFTS! EmFace lifts sagging facial skin, smooths the skin on the face and forehead, and improves texture and tone of the facial skin while removing wrinkles and stimulating underlying facial muscles to become the same size and shape as when they were younger! You may notice that you don't need a neurotoxin as often as you did before the EmFace.  You may not need as much superficial filler to erase superficial wrinkles or dimpling.  EmFace also lifts the corners of your mouth so the downturn of the corners of your mouth are not as obvious, in fact the corners of your mouth actually turn up  like they did when you were younger. This is what you've been waiting for! I know it was what I was waiting for…the EmFace machine wasn't inexpensive, so the treatments using EmFace are not cheap….but they are drastically more affordable and less dangerous than a facelift!  I have finished my series and am happy that I no longer  dread the time and risk of having a facelift in the future.

Books:Real food for pregnancyIt starts with the egg The better baby bookExpecting better Book for Partner/ husband : The Expectant Father  Naturopaths for bloodwork:Dr Justin Gallant Naturopathic Doctor  ( Hamilton) Nurture Burlington Fertility ND Podcasts: Number 1 must listen to for Pre pregnancy and Pregnancy diet Why you need a water filter : https://stephencabral.com/podcast/286/The Pregnancy podcast ( I listen to a tonne of these! she has an episode for every single topic you can think of): Best Clean Water filters: Aqua tru Reverse osmosis counter topShower filterEWG ( Product toxicity data base ) https://www.ewg.org/skindeep/Think Dirty App is amazing as well! Supplements:METHYL Folate (Not folic acid) 800mcg - 1mg minimum Methyl folate 5MTFHFish oils DHA minimums 400mg  EPA minimums 800mg CoQ10 400 - 600mg In trimester 0  Needed Prenatal My top choice but no iron you need to add separately We Natal Prenatals for men and women Thorne Suku gummies ( I used in the very beginning especially when traveling)If you liked this episode please like and share with your friends and family!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.07.527516v1?rss=1 Authors: Certain, N., Gan, Q., Bennett, J., Hsieh, H., Wollmuth, L. Abstract: AMPA receptor (AMPAR) auxiliary subunits are specialized, non-transient binding partners of AMPARs that modulate their ion channel gating properties and pharmacology, as well as their biogenesis and trafficking. The most well characterized families of auxiliary subunits are transmembrane AMPAR regulatory proteins (TARPs) and cornichon homologs (CNIHs) and the more recently discovered GSG1-L. These auxiliary subunits can promote or reduce surface expression of AMPARs in neurons, thereby impacting their functional role in membrane signaling. Here, we show that CNIH-2 enhances the tetramerization of wild type and mutant AMPARs, possibly by increasing the overall stability of the tetrameric complex, an effect that is mainly mediated by interactions with the transmembrane domain of the receptor. We also find CNIH-2 and CNIH-3 show receptor subunit-specific actions in this regard with CNIH-2 enhancing both GluA1 and GluA2 tetramerization whereas CNIH-3 only weakly enhances GluA1 tetramerization. These results are consistent with the proposed role of CNIHs as endoplasmic reticulum cargo transporters for AMPARs. In contrast, TARP {gamma}-2, TARP {gamma}-8, and GSG1-L have no or negligible effect on AMPAR tetramerization. On the other hand, TARP {gamma}-2 can enhance receptor tetramerization but only when directly fused with the receptor at a maximal stoichiometry. Notably, surface expression of functional AMPARs was enhanced by CNIH-2 to a greater extent than TARP {gamma}-2 suggesting that this distinction aids in maturation and membrane expression. These experiments define a functional distinction between CNIHs and other auxiliary subunits in the regulation of AMPAR biogenesis. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Ist deine Haut um den Mund entzündet? Hast du Bläschen und rote Stellen? Dann könnte es vielleicht eine periorale Dermatitis sein! Alex litt selbst daran und gibt in dieser Episode ihre besten Tipps, mit denen du die POD bekämpfen kannst. Außerdem erklärt sie, was sie häufigsten Auslöser/Trigger sind und wie du sie erkennst. *Mein Buch “plant.based.”: https://amzn.to/3UGlH8t  *Mein Buch “Endlich vegan”: https://amzn.to/3hVFcLT Diese Episode wird gesponsert von Norsan. Norsan ist der Experte für hochwertiges Omega 3 als Nahrungsergänzungsmittel – natürlich auch vegan aus Algenöl. Mit dem Code "sattesache15" gibt es 15 % Rabatt auf deine Neukund_innen-Bestellung. Jetzt einlösen unter: https://www.norsan.de Hier findest du Alex: Ihr Buch über POD: https://payhip.com/b/9lKp Instagram: https://www.instagram.com/alexadvice_ YouTube: https://www.youtube.com/channel/UCjkRhIrI419PQhV8F5f9p5g Liste der deklarationspflichtigen Duftstoffe: 3-Methyl-4-(2,6,6-trimethylcyclohex-2-en-1-yl)but-3-en-2-on (3-Methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one) 127-51-5 2-Benzylidenheptanal (Amyl cinnamal) 122-40-7 2-Benzylidenheptan-1-ol (Amylcinnamyl alcohol) 101-85-9 4-Methoxybenzylalkohol (Anisyl alcohol) 105-13-5 Benzylalkohol (Benzyl alcohol) 100-51-6 Benzylbenzoat (Benzyl benzoate) 120-51-4 (E)-Benzylcinnamat (Benzyl cinnamate) 103-41-3 Benzyl(2-hydroxybenzoat) (Benzyl salicylate) 118-58-1 Zimtaldehyd (Cinnamal) 104-55-2 3-Phenylprop-2-en-1-ol (Cinnamyl alcohol) 104-54-1 Citral (Citral) 5392-40-5 Citronellol (Citronellol) 106-22-9 Cumarin (Coumarin) 91-64-5 D-Limonen (d-Limonene) 5989-27-5 Eugenol (Eugenol) 97-53-0 Farnesol (Farnesol) 4602-84-0 Geraniol (Geraniol) 106-24-1 2-Benzylidenoctanal (Hexyl cinnamaldehyde) 101-86-0 7-Hydroxy-3,7-dimethyloctanal (Hydroxycitronellal) 107-75-5 rac-(1R)-4-(4-Hydroxy-4-methylpentyl)cyclohex-3-en-1- carbaldehyd (Hydroxymethylpentyl-cyclohexenecarboxaldehyde) 31906-04-4 Isoeugenol (Isoeugenol) 97-54-1 2-(4-tert-Butylbenzyl)propanal (Lilial) 80-54-6 Linalool (Linalool) 78-70-6 Methyl(oct-2-inoat) (Methyl heptine carbonate) 111-12-6 Eichenmoos (Oak moss) 90028-68-5 Baummoos (Tree moss) Barrierestärkende INCIs: - Ceramide - Bisabolol - Allantoin - Betaine - Linolsäure - Niacinamid (bis 5 %) - Licorice Extract - Vitamin E - Glycerin - Urea - Panthenol - Ectoin Ich freue mich, dich nächstes Mal wieder begrüßen zu dürfen. Es wäre toll, wenn du bei Apple Podcast eine Rezension schreibst – so hilfst du dem Podcast noch mehr Menschen zu erreichen und somit über Ernährung aufzuklären :)   Kontakt:  laura@sattesache.de https://sattesache.de https://instagram.com/sattesache *Affiliate-Links zu Amazon: Bei einem Kauf über diese Links kannst du unsere Arbeit ohne jegliche Mehrkosten unterstützen. Danke!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.30.526321v1?rss=1 Authors: Rupert, D. D., Pagliaro, A. H., Choe, J., Shea, S. D. Abstract: Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome. MECP2 codes for methyl CpG binding protein 2 (MECP2), a transcriptional regulator that activates genetic programs for experience-dependent plasticity. Many neural and behavioral symptoms of Rett syndrome may result from dysregulated timing and threshold for plasticity. As a model of adult plasticity, we examine changes to auditory cortex inhibitory circuits in female mice when they are first exposed to pups; this plasticity facilitates behavioral responses to pups emitting distress calls. Brain-wide deletion of Mecp2 alters expression of markers associated with GABAergic parvalbumin interneurons (PVin) and impairs the emergence of pup retrieval. We hypothesized that loss of Mecp2 in PVin disproportionately contributes to the phenotype. Here we find that deletion of Mecp2 from PVin delayed the onset of maternal retrieval behavior and recapitulated the major molecular and neurophysiological features of brain-wide deletion of Mecp2. We observed that when PVin-selective mutants were exposed to pups, auditory cortical expression of PVin markers increased relative to that in wild type littermates. PVin-specific mutants also failed to show the inhibitory auditory cortex plasticity seen in wild type mice upon exposure to pups and their vocalizations. Finally, using an intersectional viral genetic strategy, we demonstrate that postdevelopmental loss of Mecp2 in PVin of the auditory cortex is sufficient to delay onset of maternal retrieval. Our results support a model in which PVin play a central role in adult cortical plasticity and may be particularly impaired by loss of Mecp2. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Short Answer: I believe most methyl donor intolerances are a result of deficiencies in the glycine buffer system, which requires glycine, vitamin A, fasting (glucagon), androgens, riboflavin, unmethylated folate (THF), and iron. No one should expect to tolerate 30 milligrams of folate, however, and there is almost never a reason to use doses that high. This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link: https://chrismasterjohnphd.substack.com/p/questions-on-cognitive-health-mct In that batch of free episodes you will also find the answers to these questions: Does whey protein hurt the kidneys or otherwise hurt our health Why would someone not tolerate methyl donors even if they need them? If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up: https://chrismasterjohnphd.substack.com/qanda Learn more about the Masterpass here: https://chrismasterjohnphd.substack.com/about This snippet is from the September 14, 2022 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what's included: Why isn't my ferritin as high as diabetics when my transferrin saturation is higher? Why are vitamins A and E needed alongside D and K? Sunflower lecithin versus phosphatidylcholine supplements How do I reduce congestion while consuming dairy? Could eggs be raising triglycerides by curing fatty liver? Why would homocysteine ever be high when you can just use it to make glutathione? Why did my eye start twitching after sweating more than usual this weekend? Why do I now think A and D should be in roughly 1:1 ratios? Would MK-7 be enough to take with D or do I need MK-4? Why does water make me hungry? What's the proper ratio of calcium to magnesium, vitamin D, and vitamin K2? Is it safe to take zinc carnosine long term? Why did I recommend only using high-dose zinc for COVID protection for one year? Why did I recommend limiting quercetin phytosome to three months? Why take MK-4 when it has such a short half-life? How to make bowel movements more regular? Could freeze dried animal beef supplements cause gut infections? Do I recommend food sensitivity testing? What are the nutritional causes of restless leg syndrome? What do I think of drinking deuterium-depleted water for COVID severity? Here's a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-september Access the show notes, transcript, and comments here.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.01.08.523173v1?rss=1 Authors: Ahmadpour, N., Kantroo, M., Stobart, M. J., Salamovska, T., O'Hara, F., Erickson, D., Carrion-Falgarona, S., Stobart, J. L. Abstract: Cortical astrocytes encode sensory information through their calcium dynamics, but it remains unclear if modulation of astrocyte calcium transients can change somatosensory circuits and behaviour in vivo. Here, we used a novel knockdown approach to selectively reduce astrocyte N-methyl-D-aspartate receptors (NMDAR). We found that these ionotropic receptors contribute to astrocyte Ca2+ transients encoding sensory information. This was essential for the optimal processing of sensory information in nearby neurons, since a reduction in astrocyte NMDARs caused circuit dysfunction and impaired neuronal responses to stimulation. This led to sensory discrimination deficits in the animal. Overall, our findings show that astrocytes can rapidly respond to glutamatergic transmission via their NMDAR and these receptors are an important component for astrocyte-neuron interactions that regulate cortical sensory discrimination in vivo. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This season of the podcast, I've been working to define vitality and well-being through a framework I call the “10 Pillars of Health.” While many health experts boast a profound sense of knowledge in one or two pillars specifically, my next guest — the acclaimed Dr. Kara Fitzgerald — is incredibly well-versed in all 10.  Dr. Fitzgerald's latest book, “Younger You: Reduce Your Bio Age and Live Longer, Better,” explores the science behind longevity and her discovery of a three-year reversal of biological aging, so you know I had to get the deets. In this revelatory conversation, we cover how the following can actually hack your epigenome:  Methyl-donor nutrients (found in whole foods like beets, eggs, leafy greens, mushrooms, seeds, etc.) Methylation adaptogens (quercetin, circumin, resveratrol, green tea, etc.) Exercise Sleep Oxytocin release  And more. As always, tune into the episode to dive deeper into these essential nuggets of information. And be sure to share your thoughts with me on IG: @shoporganicolivia. Connect with Dr. Fitzgerald: Website: HERE Book: HERE Instagram: HERE Connect with Organic Olivia: My new Instagram HERE Shop herbal formulas HERE Blog HERE Thanks to our amazing sponsor Pique for supporting the show. You can access the generous offer using this link: piquelife.com/organicolivia

Alternative Methylated Biosignatures I: Methyl Bromide, A Capstone Biosignature by Michaela Leung et al. on Sunday 16 October The first potential exoplanet biosignature detections are likely to be ambiguous due to the potential for false positives: abiotic planetary processes that produce observables similar to those anticipated from a global biosphere. Here we propose a class of methylated gases as corroborative `capstone' biosignatures. Capstone biosignatures are metabolic products that may be less immediately detectable, but have substantially lower false positive potential, and can thus serve as confirmation for a primary biosignature such as O$_2$. CH$_3$Cl has previously been established as a biosignature candidate, and other halomethane gases such as CH$_3$Br and CH$_3$I have similar potential. These gases absorb in the mid infrared at wavelengths that are likely to be captured while observing primary biosignatures such as O$_3$ or CH$_4$. We quantitatively explore CH$_3$Br as a new capstone biosignature through photochemical and spectral modeling of Earth-like planets orbiting FGKM stellar hosts. We also re-examine the biosignature potential of CH$_3$Cl over the same set of parameters using our updated model. We show that CH$_3$Cl and CH$_3$Br can build up to relatively high levels in M dwarf environments and analyze synthetic spectra of TRAPPIST-1e. Our results suggest that there is a co-additive spectral effect from multiple CH$_3$X gases in an atmosphere, leading to increased signal-to-noise and greater ability to detect a methylated gas feature. These capstone biosignatures are plausibly detectable in exoplanetary atmospheres, have low false positive potential, and would provide strong evidence for life in conjunction with other well established biosignature candidates. arXiv: http://arxiv.org/abs/http://arxiv.org/abs/2208.07393v2

Alternative Methylated Biosignatures I: Methyl Bromide, A Capstone Biosignature by Michaela Leung et al. on Sunday 16 October The first potential exoplanet biosignature detections are likely to be ambiguous due to the potential for false positives: abiotic planetary processes that produce observables similar to those anticipated from a global biosphere. Here we propose a class of methylated gases as corroborative `capstone' biosignatures. Capstone biosignatures are metabolic products that may be less immediately detectable, but have substantially lower false positive potential, and can thus serve as confirmation for a primary biosignature such as O$_2$. CH$_3$Cl has previously been established as a biosignature candidate, and other halomethane gases such as CH$_3$Br and CH$_3$I have similar potential. These gases absorb in the mid infrared at wavelengths that are likely to be captured while observing primary biosignatures such as O$_3$ or CH$_4$. We quantitatively explore CH$_3$Br as a new capstone biosignature through photochemical and spectral modeling of Earth-like planets orbiting FGKM stellar hosts. We also re-examine the biosignature potential of CH$_3$Cl over the same set of parameters using our updated model. We show that CH$_3$Cl and CH$_3$Br can build up to relatively high levels in M dwarf environments and analyze synthetic spectra of TRAPPIST-1e. Our results suggest that there is a co-additive spectral effect from multiple CH$_3$X gases in an atmosphere, leading to increased signal-to-noise and greater ability to detect a methylated gas feature. These capstone biosignatures are plausibly detectable in exoplanetary atmospheres, have low false positive potential, and would provide strong evidence for life in conjunction with other well established biosignature candidates. arXiv: http://arxiv.org/abs/http://arxiv.org/abs/2208.07393v2

https://psychiatry.dev/wp-content/uploads/speaker/post-9720.mp3?cb=1663480613.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Interactions between dopamine transporter and N-methyl-d-aspartate receptor-related amino acids on cognitive impairments in schizophrenia – PubMed Kai-Chun Yang et al. Schizophrenia Research.Full EntryInteractions between dopamine transporter and N-methyl-d-aspartate receptor-related amino acids on cognitive impairments in schizophrenia – PubMed

The episode that EVERY soon to be conceiving, or pregnant mama should be listening to. What exactly are the differences between folic acid and methyl-folate? What does your body have to do to both of them?Why do some supplements use folic acid, and others methyl-folate?And why methyl-folate comes out as Queen in this debate, each and every time. Remember to give my podcast a 5-star review if you are loving it and share it with a friend of family member who is looking to get pregnant, or is currently pregnant, so that they can learn why they need methyl-folate. 

Dr. Ted Achacoso is a European double-board certified in Nutritional Medicine and Anti-Aging Medicine.  Thank you to our sponsors, 10% off with promo code ( justin10 ) Connect with Dr. Achacoso https://www.facebook.com/drtedachacoso/ https://biobalanceinstitute.com/ https://troscriptions.com/

Drugs n Stuff 140 w/ Dave Crosland & Scott McNally - TIME STAMPS BELOW

References Dr. Guerra's synthesis of the epitranscriptome lecture notes Sci Signal. 2017 Jan 31; 10(464): eaaf7478. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

Autism Expert and pioneer in the field of Autism, Psychologist and BCBA, Dr. Doreen Granpeesheh is answering viewer questions about Methyl B12, Meltdowns, ADHD medication and more!  3:48 Shannon's Happy Birthday Message to Dr. Doreen Granpeesheh 9:25 Happy Birthday Wishes from Viewers to Dr. Doreen Granpeesheh 11:23 Hi, what can MB12 shots do for my 9-year-old son? Diagnosed with ASD and nonverbal, he started with his first shot today. 16:54 I experience that people Get angry at me a lot I'm tired of it! It makes me sad! Why do people Get outburst at me often? I don't trust people just leave me or reject me. Christians wants my autism to go away its very hurtful -and they want to pray it away like i was filled with demons I'm a Christian myself! 24:55 Will you ever do a call-in show? 25:18 I'm so defeated my son started medication before his ADHD and he has tried several they all make him emotional, aggressive, and irritable. He started ABA yesterday and I had to pick him up he meltdown. 37:55 Our school wants us to consider sending our 9 yrs old daughter to another school where they have 8/3 ratio because she isn't keeping up academically. We worry that this will not be an inclusive experience and will affect her mental health. How will she do moving away from her only friend and the anxiety of a new school? 42:19 Hello, how can I help my 20yr old son who wanted to attempt suicide last week, he's coming out of the mental hospital in a few days, now I don't know how to treat him, he's not on the spectrum. His younger brother is the one with autism, please help me with any advice you may have. 53:21 How do I get help for My autism, but I have no money or a support system at all. 58:41 This week on Autism Live

Autism Expert and pioneer in the field of Autism, Psychologist and BCBA, Dr. Doreen Granpeesheh is answering viewer questions about Methyl B12, Meltdowns, ADHD medication and more!  3:48 Shannon's Happy Birthday Message to Dr. Doreen Granpeesheh 9:25 Happy Birthday Wishes from Viewers to Dr. Doreen Granpeesheh 11:23 Hi, what can MB12 shots do for my 9-year-old son? Diagnosed with ASD and nonverbal, he started with his first shot today. 16:54 I experience that people Get angry at me a lot I'm tired of it! It makes me sad! Why do people Get outburst at me often? I don't trust people just leave me or reject me. Christians wants my autism to go away its very hurtful -and they want to pray it away like i was filled with demons I'm a Christian myself! 24:55 Will you ever do a call-in show? 25:18 I'm so defeated my son started medication before his ADHD and he has tried several they all make him emotional, aggressive, and irritable. He started ABA yesterday and I had to pick him up he meltdown. 37:55 Our school wants us to consider sending our 9 yrs old daughter to another school where they have 8/3 ratio because she isn't keeping up academically. We worry that this will not be an inclusive experience and will affect her mental health. How will she do moving away from her only friend and the anxiety of a new school? 42:19 Hello, how can I help my 20yr old son who wanted to attempt suicide last week, he's coming out of the mental hospital in a few days, now I don't know how to treat him, he's not on the spectrum. His younger brother is the one with autism, please help me with any advice you may have. 53:21 How do I get help for My autism, but I have no money or a support system at all. 58:41 This week on Autism Live

Welcome to Episode 92 Sponsored by CultTVMan,  Sean's Custom Model Tools and Return To Kit Form Hosts Stuart Clark Geoff Heyland Terry Miesle Thanks to our latest Patreon Supporters: ***************************************  Hobby News Noreastcon 50 Bandai tightening up on int distribution. https://www.facebook.com/MechaAlliance/posts/4897902883655991 https://www.facebook.com/permalink.php?story_fbid=511992363898713&id=100711051693515 Humbrol Enamels off of their website. – Part of a ban on Methyl […]

One of the common questions parents of children with special needs ask,"How do I know if hyperbarics is working for my child?" In this episode I am speaking with Dr. James Neubrander, MD about special diagnostic forms that allow to measure progress in Hyperbaric Oxygen Therapy for children on autistic spectrum. Dr. Neubrander is famous for discovering Methyl-B12 treatment for children on autistic spectrum. He is one of the pioneers of hyperbaric oxygen therapy use for children with autism and other neurodevelopmental disorders. He has treated more than 4,000 children on the spectrum with 100,000 hrs of hyperbarics and 1.5 million doses of Methyl B-12. Dr. Neubrander developed unique diagnostic protocols that allow parents to document ‘undeniable changes' from HBOT and Methyl-12 use and know whether these therapies are "working". In this episode Dr. Neubrander explains how to use a special evaluation form to know whether hyperbarics is working, how to measure progress with any therapy to map future treatments accordingly. We are discussing specific protocols, pressures and number of hyperbaric sessions. 4:16 The history of first at-home use of hyperbarics. Patient story 5:13 The importance of "keep going" with HBOT 11:00 How methyl-B12 for children with autism was discovered 14:43 Methyl B-12 Patient Story 18:54 How many HBOT sessions are needed? 20:50 HBOT protocol Dr. Neubrander uses for his patients on autistic spectrum 25:17 How to use an HBOT evaluation form? 28:40 Can hyperbarics not work at all? 31:33 Should you take breaks from HBOT 34:23 What about an oxygen concentrator for a child on autistic spectrum 35:55 What is the optimal hyperbaric pressure for children with autism 39:15 Effect of HBOT on yeast overgrowth and what to do about it Dr. James Neubrander can be found at https://www.drneubrander.com To learn how you can benefit from Hyperbaric Oxygen Therapy, go to www.drmasha.com/hbot/ to book your free 15-minute consultation with Dr. Masha, the Hyperbaric Living podcast host This podcast is for informational purposes only and does not substitute a medical advice. The information presented is not meant to diagnose, treat, cure, or prevent disease. We recommend you seek the advice of a licensed healthcare practitioner before beginning any natural, complimentary, or conventional treatment. #hbot #mhbot #hyperbaricoxygentherapy #hyperbaricchamber #autism #autisticspectrum #specialneeds #methylb12 #podcast #hyperbaric_living

Seafood is a classic heart-healthy food. It is part of the Mediterranean diet that can lower blood pressure. Fish consumption was shown in several studies to lower the risk of death in patients with coronary artery disease. Seafoods are traditionally low in saturated fats, rich in iron, iodine and in omega-3 fatty acids. But also seafoods contain Methyl mercury which is produced by microorganisms in water and soil, and accumulates in fish. Recently, many people choose to limit their seafood consumption because of fear of mercury exposure from seafood. Excessive mercury may adversely affect the nervous system in infants and pregnant ladies and lactating mothers should avoid exposure to mercury because of its effects on the fetus. So what should we do? Consume fish and seafood to get the benefits on the CV system or reduce or intake to avoid exposure to mercury?https://www.fda.gov/food/consumers/advice-about-eating-fish

In this episode we take a look into Coal tar, Petroleum, Jet fuel and the thing that binds them all together - 1,2,3-Trimethylbenzene. See how this compound has impacted the ways we live for hundreds of years and made possible advancements that have taken us around the world.   Like, Share and Comment to help spread the good times! For all updates on new episodes, follow me on Twitter here: @PodcastTale or Facebook here: @PodcastTale   https://toastedtale.podbean.com/

This is the first of my 3-part podcast series in my MDMA experience. Methyl​enedioxy​methamphetamine (MDMA) is commonly known as ecstasy (E) or molly. This episode discusses what I did to prep with my personal trauma therapist, Internal Family Systems Therapist, and Psychedelic Integrative Therapist, Heather Smith.  In my journey to healing, I have been privileged enough to explore the many treatment modalities out there, including having MDMA to support my work in therapy.  In my search for more information about MDMA assisted therapy, I realized Internal Family Systems, or IFS therapy was effective in the preparation of the treatment as well as integration afterward.

WELCOME to The WELLNESS FOURplay Podcast Episode 22: B.I.I. - What every Woman with Breast Implants, or considering them, MUST know! What every Woman with Breast Implants, or considering them, MUST know! We KNOW that Knowledge is the "foreplay" to your Wellness, so we want to make sure you are equipped to be your OWN Super Hero in your wellness journey! Equipping you with the KNOWLEDGE you need to have the HEALTH you so desire!  1. WHAT IS B.I.I.?  Breast implant illness (BII) is a term that some women and doctors use to refer to a wide range of symptoms that can develop after undergoing reconstruction or cosmetic augmentation with breast implants. It is also sometimes referred to as autoimmune/inflammatory syndrome induced by adjuvants (ASIA). BII can occur with any type of breast implant, including silicone gel-filled, saline-filled, smooth surface, textured surface, round, or teardrop-shaped. BII is not currently recognized as an official medical diagnosis, and there is no diagnosis code for it. It is poorly understood and hasn't been studied much as a unique condition. Implants are a foreign object placed inside of the body that our Immune Systems actively go to war with. May 2, 2019, the FDA issued a statement acknowledging breast implant illness and the systemic symptoms caused by silicone. Saline was said to be safe... WHY are they listed? The casing of the implant is SILICONE that contains: Methyl Ethyl Ketone (neurotoxin), Cyclohexanone (neurotoxin), Isopropyl Alcohol, Acetone (neurotoxin), Urethane, Polyvinyl Chloride (neurotoxin), Amine, Toluene (neurotoxin/carcinogen), Dichloromethane (carcinogen), Chloromethane, Ethyl Acetate (neurotoxin), Sodium Fluoride, Lead-based solder, Formaldehyde, Oakite (cleaning solvent), Methyl 2-cyanoacryltes, Ethylene Oxide (carcinogen), Xylene (neurotoxin) -2-Hexanone, Stearic Acid, Zinc Oxide, Phenol (neurotoxin), Benzene (carcinogen/neurotoxin), Lacquer Thinner, Epoxy Resin, Metal Cleaning Acid, Heavy metals, and more! 2. WHAT ARE THE SYMPTOMS OF B.I.I. AND POTENTIAL MIS-DIAGNOSIS THAT CAN BE MADE?  BII impacts each individual in a unique way. Symptoms can include: Joint and muscle pain, chronic fatigue, memory and concentration problems, breathing problems, sleep disturbance, rashes and skin problems, dry mouth and dry eyes, anxiety, depression, headache, hair loss, gastrointestinal problems and more. The symptoms can appear any time after implant surgery — some people develop symptoms immediately, while some develop them years later. A lot of the symptoms of BII are associated with autoimmune and connective tissue disorders, such as lupus, rheumatoid arthritis, and scleroderma. Some people who have BII also get diagnosed with a specific autoimmune or connective tissue disorder, but many do not. 3. WHY ARE WE TALKING ABOUT B.I.I.?  B.I.I. is a real illness that women with, and those thinking about, implants MUST know about. 100's of 1000's of women have already taken measures to recover from B.I.I. Marci has been working through many of the above symptoms for years, attributing them to incidents in her life: Car accidents, brain injuries, concussions, spine surgeries, full anesthesia 5 times in a 4-month span, pain medications, turning 50. Diet, exercise, sleep, heavy metal detox, mindset and Biohacking Synergy has kept her highly functional and undiagnosed, but not alleviated the symptoms she is living with. Marci's current list of symptoms: Fatigue, brain fog, memory loss, cognition problems, muscle pain and weakness, joint pain (neck, back, hands, feet, shoulder), weight problems (weight gain, bloating), inflammation, poor sleep, dry eyes with a decline in vision, low libido, headaches, ear ringing, metallic taste and dry mouth, mouth sores, sudden food intolerances, bouts of dehydration for no reason, numbness and tingling in left arm, cold and discolored feet/hands (Reynaud's Syndrome), pain and burning around left breast and underarm, depression, anxiety, mood swings, throat tickles with coughing fits, hair loss/dry hair, tingle and burning down left side of face/shoulder/arm. Thanks to prayer, resources and information showed up... Clubhouse Room Facebook Group with 140k+ members Website. The Heal is REAL Friend (personal experience & clients). Over the past 2 months, an awareness of BII has put her personally on a healing journey. 4. WHAT'S NEXT?  In many, but not all cases, surgery to remove the breast implants improves or completely resolves the BII symptoms. Explant surgery scheduled for August 4, 2021 or sooner with God's grace. For more information on BII, Marci's Biohacking regimen, Heavy Metal detox smoothy, the Facebook Support Group and Website, please contact us at DondeeAndMarci.com and make sure to mention Episode 22 and what specific information you would like. #WellnessFourPlay​ #ProactiveWellness​ #BII​ #BreastImplantIllness​ #AutoImmuneDisorders​ #TheHealIsReal​ #TheBiohackingTeam​ #EmpoweredWellness​ #wellness

In this episode we talk about the use of Methyl Bromide with Pam Peckman. Pam is in charge of Regulatory Compliance and Technical Services at IFC, and has extensive knowledge on the continued use of the fumigant.   Disclaimer: This podcast is meant to be entertaining and informative.  The views expressed by guests are their own and their appearance on the program does not imply any endorsement of them or any entity they represent. Views and opinions expressed by Degesch America employees are those of the employees and do not necessarily reflect the view of Degesch America or any of its officials. You must read and follow the label directions and check with any and all regulatory agencies before using, storing or transporting any materials discussed.  Our goal is to bring awareness to different aspects of the pest control industry; and hopefully by doing this, we can help make our industry a little bit safer. 

Dr. Don and Professor Ben talk about the risk of methanol hand sanitizer. Dr. Don - risky ☣️ Professor Ben - risky ☣️ FDA updates on hand sanitizers consumers should not use | FDA Serious Adverse Health Events, Including Death, Associated with Ingesting Alcohol-Based Hand Sanitizers Containing Methanol — Arizona and New Mexico, May–June 2020 | MMWR 8 People in U.S. Have Died After Ingesting Hand Sanitizer Containing ‘Toxic' Methanol Toxicity of Methyl alcohol (Methanol) Following Skin Absorption and Inhalation | Industrial & Engineering Chemistry The hidden danger of hand sanitizer | MDedge Psychiatry