Podcasts about neuronal

Dr. Sarah McKay, a brilliant neuroscientist, takes us on a thrilling adventure into the intricate dance between hormones and the female brain during menopause. She shares her personal quest to unravel how those mischievous hormonal shifts tweak women's brains from 40 onwards, revealing the fascinating secrets of neuronal 'pruning and tuning.' Dr. McKay also shines a spotlight on the superstars estrogen, dopamine, and serotonin, and uncovers how our social circles and daily choices play a massive role in brain health. With sparkling discussions on metabolic health and the wider ripple effect of menopause, this episode is a must-listen for any woman eager to keep her brain sparkling and sharp! To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://drmindypelz.com/ep311 Dr. Sarah McKay is a neuroscientist and science communicator who makes brain science practical and accessible for better health, wellbeing, and performance. She holds an MSc and PhD from Oxford and spent five years researching spinal cord injury before founding Think Brain, her science education company. Sarah's appeared on ABC's Catalyst, The Mel Robbins Podcast, SBS Insight, and has been featured in The Wall Street Journal, The Guardian, and Australian Women's Weekly. She's the author of The Women's Brain Book, Baby Brain, and Brain Health for Dummies, all exploring how understanding the brain can help us live and feel better. Check out our fasting membership at https://esetacademy.drmindypelz.com. Please note our medical disclaimer.

El aprendizaje, la memoria, nuestro sentido del yo, residen en la compleja red de conexiones de las neuronas y el diálogo continuo que mantienen con otras células cerebrales. Entender esos mecanismos no solo es fundamental para conocer el software cerebral… También para comprender que es lo que falla en enfermedades neurológicas como el Alzheimer. Ese el objetivo de Manuel Valero, director del Laboratorio de Computación Neuronal en el Instituto de Investigación Hospital del Mar, a quien hemos entrevistado en el programa. Las aguas termales transportan y depositan minerales, interactúan con las rocas a través de procesos químicos y sirven como indicadores de la actividad geológica subyacente. Ese hidrotermalismo no es exclusivo de la Tierra. También se produce en otros cuerpos celestes y, como nos ha contado Jesús Martínez Frías, también se ha detectado en las muestras del asteroide Bennu traídas a la Tierra por la misión de la NASA Osiris-Rex. Con Jesús Puerta hemos analizado una de las cuestiones que intrigan a los científicos: Por qué en el universo domina la materia si el Big Bang se formó una cantidad similar de antimateria. Y la respuesta está en la simetría de algunas partículas elementales. José Manuel Torralba nos ha hablado del sistema robótico de Inteligencia Artificial A-Lab que produce y analiza materiales sin intervención humana. Este sistema está en comunicación con otro que es capaz de predecir la existencia de cientos de miles de materiales estables, lo que dará al A-Lab un montón de candidatos a los que aspirar en el futuro. María González Dionis nos ha contado el hallazgo de nuevos fósiles de pies y manos del “Hombre cascanueces” (Paranthropus boisei) que revelan que sus manos podían agarrar objetos y manejar herramientas como los humanos primitivos y trepar a los árboles como los gorilas.Escuchar audio

El aprendizaje, la memoria, nuestro sentido del yo, residen en la compleja red de conexiones de las neuronas y el diálogo continuo que mantienen con otras células cerebrales. Entender esos mecanismos no solo es fundamental para conocer el software cerebral… También para comprender que es lo que falla en enfermedades neurológicas como el Alzheimer. Ese el objetivo de Manuel Valero, director del Laboratorio de Computación Neuronal en el Instituto de Investigación Hospital del Mar, a quien hemos entrevistado en el programa. Las aguas termales transportan y depositan minerales, interactúan con las rocas a través de procesos químicos y sirven como indicadores de la actividad geológica subyacente. Ese hidrotermalismo no es exclusivo de la Tierra. También se produce en otros cuerpos celestes y, como nos ha contado Jesús Martínez Frías, también se ha detectado en las muestras del asteroide Bennu traídas a la Tierra por la misión de la NASA Osiris-Rex. Con Jesús Puerta hemos analizado una de las cuestiones que intrigan a los científicos: Por qué en el universo domina la materia si el Big Bang se formó una cantidad similar de antimateria. Y la respuesta está en la simetría de algunas partículas elementales. José Manuel Torralba nos ha hablado del sistema robótico de Inteligencia Artificial A-Lab que produce y analiza materiales sin intervención humana. Este sistema está en comunicación con otro que es capaz de predecir la existencia de cientos de miles de materiales estables, lo que dará al A-Lab un montón de candidatos a los que aspirar en el futuro. María González Dionis nos ha contado el hallazgo de nuevos fósiles de pies y manos del “Hombre cascanueces” (Paranthropus boisei) que revelan que sus manos podían agarrar objetos y manejar herramientas como los humanos primitivos y trepar a los árboles como los gorilas.Escuchar audio

"Im Alter von 0 bis 2 Jahren sollte Bildschirmzeit komplett vermieden werden. Hier sehen wir nachweislich eine Veränderung zum Beispiel in der Entwicklung der Sprache." – Smartphones, Tablets, YouTube, Games, Netflix & Co. – Kinder wachsen heute in einer Dauerverfügbarkeit von Reizen auf. Gleichzeitig steigen Konzentrationsprobleme, Schlafstörungen, motorische Defizite und emotionale Dysbalancen. Doch was passiert biologisch, wenn ein Kind regelmäßig auf einen Screen schaut? Kinder mit Smartphones – ein Thema, das sofort Emotionen weckt. Was macht regelmäßige Bildschirmnutzung im Kinder- und Jugendalter mit Körper, Gehirn und Psyche? Und wie viel ist zu viel? Podcast-Host Felix Moese und Gesundheitswissenschaftler Matthias Baum sind selbst Eltern kleiner Kinder. Die beiden tauchen tief ein in die Welt digitaler Reize und erklären die physiologischen, neurologischen und evolutionsbiologischen Zusammenhänge – jenseits von moralischer Panik, dafür wissenschaftlich fundiert und verständlich. Sie zeigen, wie Bildschirmzeit das kindliche Gehirn beeinflusst, warum das Belohnungssystem überstimuliert wird – und was das für Konzentration, Motivation und emotionale Entwicklung bedeutet. Besonders in den ersten Lebensjahren reagiert das Gehirn sensibel auf Reize – digitale Überforderung kann die neuronale Verschaltung langfristig verändern. Ein weiterer Schwerpunkt: der Zusammenhang zwischen Licht, Melatonin und Schlaf – und warum abendliches Scrollen nicht nur Kinder künstlich wach hält. Außerdem sprechen Felix und Matthias über die psychologischen Folgen von Social Media: den Vergleich mit anderen, den ständigen Dopamin-Kick – und warum das Risiko für ADHS-ähnliche Symptome steigt (übrigens auch bei Erwachsenen). Wie immer bleibt es nicht bei der Analyse: Felix und Matthias geben Orientierung für den Alltag. Sie zeigen konkrete Wege, wie Eltern ihre Kinder begleiten können, um digitale Kompetenz zu fördern statt Verbote auszusprechen. Mit praktischen Tipps – vom Co-Viewing bis zu klaren Offline-Zeiten. Am Ende steht die Erkenntnis: Digitale Medien sind weder gut noch böse. Entscheidend ist, wie bewusst wir sie nutzen – und ob Kinder noch genug Raum haben für das, wofür ihr Gehirn evolutionär vorgesehen ist: Bewegung, Begegnung und Erlebnisse in der realen Welt. HEALTH NERDS – Mensch, einfach erklärt. Ein ALL EARS ON YOU Original Podcast.

In this podcast, Alessandro Simonati discusses his paper 'Age at onset and gene variants predict lifespan and disease duration in childhood neuronal ceroid lipofuscinoses'.   The paper is available here: https://doi.org/10.1111/dmcn.16416   Follow DMCN on Podbean for more:  https://dmcn.podbean.com/ ___ Watch DMCN Podcasts on YouTube: https://bit.ly/2ONCYiC __ DMCN Journal: Developmental Medicine & Child Neurology (DMCN) has defined the field of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families.   DMCN Journal - https://onlinelibrary.wiley.com/journal/14698749 ___ Find us on Twitter! @mackeithpress - https://twitter.com/mackeithpress

Stanislas DehaeneChaire Psychologie cognitive expérimentaleAnnée 2025-2026Collège de FranceColloque : Seeing the Mind, Educating the BrainTheme: Numerical and Mathematical DevelopmentIlluminating Fractions Learning: Neuronal Recycling of Non-Symbolic Ratios for Symbolic FractionsColloque - Edward Hubbard : Illuminating Fractions Learning: Neuronal Recycling of Non-Symbolic Ratios for Symbolic FractionsEdward HubbardRésuméWithin mathematics, fractions hold a special place. They present perennial difficulties to students, and yet, mastering fractions is a critical stepping stone towards algebra and higher-order mathematics. More than 20 years ago, Stanislas Dehaene suggested that fractions are difficult because they lack the intuitive perceptual foundation that permits us to readily comprehend whole numbers and instead may depend on formal and symbolic processes. Here, I will present research from my lab showing that fractions may indeed have a perceptual foundation, and that this perceptual foundation may be recycled to allow us to understand symbolic fractions. Behaviorally, we have shown that symbolic fractions do not need to be processed componentially and instead can be represented on a coherent mental number. We show that wholistic fraction comparisons (and translation to decimals) does not require time consuming computations, and that non-symbolic ratio perception in college students and American elementary school children predicts formal fractions skills. Using fMRI, we have further shown that non-symbolic ratio perception reliable recruits right parietal cortex, even before the onset of formal schooling, and these parietal systems become tuned to symbolic fractions after as little as two years of formal education. Despite this evidence that fractions do, indeed, have a perceptual foundation, they still present significant difficulties. I will close by arguing that fractions (and other domains) may be difficult not due to a lack of foundational systems, but rather, due to educational methods that fail to align with these perceptual foundations. Furthermore, I will argue that research in numerical cognition can (and should!) provide new pedagogical approaches that better align with the foundational systems we have discovered to help students better grasp higher-order mathematical concepts. 

Stanislas DehaeneChaire Psychologie cognitive expérimentaleAnnée 2025-2026Collège de FranceColloque : Seeing the Mind, Educating the BrainTheme: Perception and ConsciousnessThe Global Neuronal Workspace from the Molecular to the Cognitive Level: Consequences for Pathology and PharmacologyColloque - Jean-Pierre Changeux : The Global Neuronal Workspace from the Molecular to the Cognitive Level: Consequences for Pathology and PharmacologyJean-Pierre ChangeuxRésuméThe global neuronal workspace (GNW) theory originates from decades-long productive dialogs between Dehaene & Changeux which aimed, in the late 80's, at the elaboration of formal neuronal networks of cognitive functions. They initially included birdsong learning by selection, the Wisconsin card sorting task, infants numerosity detection...All these models were grounded on a molecular level which included allosteric neurotransmitter receptors. In 1998, the "global neuronal workspace" was integrated into a formal organism in order to pass the effort-full, "conscious", Stroop task. It was postulated to consist of a brain-scale—multimodal & horizontal—network of widely distributed neurons with long axon neurons, distinct from modality-specific localized non-conscious processors, including neurons which included the prefontal, parieto-temporal, cingulate… areas. The access of an outside representation to the conscious workspace would manifest itself by an "ignition" of the workspace network. At this stage, an important number of imaging and electrophysiological data appear consistent with the GNW theory. In this contribution, emphasis shall be given to the bottomup contribution of the molecular level and its consequences for the understanding of neuropsychiatric diseases and rational drug design, in the larger context of a novel precision pharmacology.

Stanislas DehaenePsychologie cognitive expérimentaleCollège de FranceAnnée 2025-2026Colloque: Seeing the Mind, Educating the BrainPart 1: Seeing and Decoding the MindConscious Perception: The Propagation of Selection Signals through the Global Neuronal WorkspaceColloque - Pieter Roelfsema: Conscious Perception: The Propagation of Selection Signals through the Global Neuronal WorkspacePieter RoelfsemaNetherlands Institute for Neuroscience, Amsterdam & Institut de la Vision, ParisRésuméhe Global Neuronal Workspace (GNW) theory (Baars, 1988; Dehaene et al., 1998) proposes that information must be broadcast across widely distributed networks to enter conscious awareness. But what exactly is the information that is exchanged? I will argue that the GNW provides the substrate for the spread of selection signals and use this perspective to refine the distinction between access and phenomenal consciousness.Access consciousness corresponds to the information currently circulating within the GNW. In perception, this is the information selected by object-based attention, enabling a degree of representational flexibility that would otherwise not be attainable. In thought, access consciousness corresponds to the attended content of working memory, i.e. the items that can be actively transformed, combined, or used to retrieve associations. Phenomenal consciousness, by contrast, refers to the set of representations that are not yet part of the GNW, but that could be attended next because they are captured by the senses or because they are in an unattended memory form.I will illustrate these ideas in perception and memory. Perceptual experiments address the construction of coherent object representations through the spread of object-based attention, which at a neuronal level, corresponds to the spread of enhanced activity. In these studies, access consciousness aligns with object-based attention, and the GNW acts as the scaffold that allows selection signals to label all features of a perceptual object. This binding mechanism is incremental, time-consuming and explains why we consciously perceive unified, multi-feature objects.When considering memory, I will contrast iconic memory, supported by transient activity in early visual cortex, to working memory representations in higher areas that are maintained by persistent firing. Items in access awareness are attended within working memory and show stronger and more stable activity than non-attended items. I will show how the spread of selection signals among attended working memory items through the GNW supports conscious cognitive functions, such as resolving pronouns during reading and the retrieval of associations between concepts.Together, these findings suggest a revised view of the relationship between attention and consciousness, positioning the GNW as the orchestrator of distributed neuronal representations through the spread of attentional selection signals.

Stanislas DehaeneChaire Psychologie cognitive expérimentaleAnnée 2025-2026Collège de FranceColloque : Seeing the Mind, Educating the BrainPart 1: Seeing and Decoding the MindExploring Consciousness at the Edge: Global Neuronal Workspace Framework & NeurologyColloque - Lionel Naccache : Exploring Consciousness at the Edge: Global Neuronal Workspace Framework & NeurologyLionel NaccacheRésuméAfter a brief synthetic introduction to the Global Neuronal Workspace (GNW) theoretical framework, I will show how the exploration of conscious state and conscious access in extreme neurological or physiological conditions can be mutually beneficial by: (i) improving medical and ethical care of patients, and (ii) enriching cognitive neuroscience of consciousness by testing key theoretical predictions in unusual situations. I will illustrate this bidirectional approach by focusing on Disorders of Consciousness (i.e.: vegetative states also coined unresponsive wakefulness syndrome, minimally conscious state and related conditions), but I will also address more briefly key recent findings in epilepsy, hemispherotomy and sleep.

Stanislas DehaeneChaire Psychologie cognitive expérimentaleAnnée 2025-2026Collège de FranceColloque : Seeing the Mind, Educating the BrainPart 2: Training and Educating the BrainThe Neuronal Basis of Numerical Cognition in Humans and Nonhuman PrimatesColloque - Andreas Nieder : The Neuronal Basis of Numerical Cognition in Humans and Nonhuman PrimatesAndreas NiederInstitut de neurobiologie, département de biologie, université de Tübingen, AllemagneRésuméOur understanding of numbers, vital to our scientifically and technically advanced culture, has deep biological roots. Research across developmental psychology, anthropology, and animal cognition suggests that our ability to count symbolically arises from more primitive non-symbolic number representations. By studying single-neuron activity in associative brain areas of awake human patients and monkeys, we aim to uncover the physiological principles behind how numbers are represented in the brain. In both species, we've identified "number neurons" that encode set sizes regardless of how the stimuli are presented. These neurons play a crucial role in processing numerical information during goal-directed behavior. Moreover, investigating how numbers are processed in working memory offers insights into high-level cognitive control functions. Comparative research in numerical cognition is uniquely positioned to unravel the brain processes enabling humans to transition from nonsymbolic to symbolic representations, a hallmark of our species.

La neurocientífica Liset Menéndez de la Prida investiga en el Instituto Cajal cómo nuestro cerebro es capaz de recordar el camino a casa, encontrar la salida de una habitación u organizar los recuerdos a lo largo del tiempo. Pere Estupinyà y Javier Sampedro charlan con ella en esta interesantísima conversación sobre el estudio de la actividad neuronal y la construcción mental del tiempo.

La neurocientífica Liset Menéndez de la Prida investiga en el Instituto Cajal cómo nuestro cerebro es capaz de recordar el camino a casa, encontrar la salida de una habitación u organizar los recuerdos a lo largo del tiempo. Pere Estupinyà y Javier Sampedro charlan con ella en esta interesantísima conversación sobre el estudio de la actividad neuronal y la construcción mental del tiempo.

Moderator: James Rathmell, M.D. Participants: Shiqian Shen, M.D. and Cyrus David Mintz, M.D., Ph.D. Articles Discussed: Hippocampal Neural Dynamics and Postoperative Delirium-Like Behavior in Aged Mice Neural Network Dynamics of Postoperative Delirium: is it all About Neurons Striking the Right Balance? Transcript

In this episode of the Epigenetics Podcast, we talked with Erica Korb from the University of Pennsylvania about her work on BRD4 and the histone variant H2BE, which influences synaptic genes and neuronal activity. Dr. Korb discusses the focus of her lab, which centers on epigenetic mechanisms impacting gene regulation in neurons. Her research primarily examines histone biology and its connection to neurodevelopmental disorders, including autism spectrum disorder and intellectual disabilities. Dr. Korb expounds on the collaborative environment at UPenn's Epigenetics Institute, emphasizing how the rich diversity of research topics fosters innovative ideas and projects within the community. Reflecting on her earlier work from her postdoctoral studies, Dr. Korb discusses her first significant findings regarding the protein BRD4. This work demonstrated BRD4's role in mediating transcriptional regulation crucial for learning and memory processes. She explains how disrupting this protein's function in neurons hindered critical gene activations required for memory formation in mice. This foundational understanding opened avenues for exploring the broader implications of chromatin regulation in various neurodevelopmental conditions. Transitioning into her current research endeavors, Dr. Korb reveals how she aims to expand her focus beyond Fragile X syndrome. With her lab now investigating multiple chromatin regulators implicated in various forms of autism spectrum disorders, she describes a recent project where RNA sequencing exposed substantial overlaps in gene expression changes associated with five distinct chromatin modifiers, each contributing uniquely to neuronal function while collectively demonstrating sensitivity to chromatin disruptions. A significant portion of the discussion centers around Dr. Korb's unexpected exploration into how COVID-19 intersects with chromatin biology through a phenomenon known as histone mimicry. Leveraging bioinformatic tools during the pandemic, her lab discovered that certain viral proteins mimic histone sequences, which may lead to altered transcriptional outputs in host cells. This coincidental finding illustrates both the creative adaptability needed in scientific research and the importance of collaborative efforts across disciplines to uncover new insights. The conversation also delves into Dr. Korb's recent work regarding the histone variant H2BE, initiated by one of her graduate students. She explains how prior research only recognized H2BE's expression in the olfactory system, yet her lab has demonstrated its significant role in regulating synaptic genes and memory formation throughout broader neuronal contexts. Notably, they identified a single amino acid change that influences H2BE's function in chromatin accessibility and gene transcription, emphasizing its potential evolutionary conservation across species. In terms of H2BE's role, Dr. Korb elucidates that its activity is integral in response to extracellular stimuli, particularly within the context of neuronal activation. Intriguingly, they found that H2BE expression decreases in reaction to long-term neuronal stimulation, suggesting a complex mechanism of homeostatic plasticity crucial for regulating neuronal activity levels. This research not only advances understanding of chromatin dynamics but also holds implications for neuronal health and disease mechanisms.   References Feierman, E. R., Louzon, S., Prescott, N. A., Biaco, T., Gao, Q., Qiu, Q., Choi, K., Palozola, K. C., Voss, A. J., Mehta, S. D., Quaye, C. N., Lynch, K. T., Fuccillo, M. V., Wu, H., David, Y., & Korb, E. (2024). Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long-term memory. Molecular cell, 84(15), 2822–2837.e11. https://doi.org/10.1016/j.molcel.2024.06.025 Korb, E., Herre, M., Zucker-Scharff, I., Gresack, J., Allis, C. D., & Darnell, R. B. (2017). Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. Cell, 170(6), 1209–1223.e20. https://doi.org/10.1016/j.cell.2017.07.033 Kee, J., Thudium, S., Renner, D. M., Glastad, K., Palozola, K., Zhang, Z., Li, Y., Lan, Y., Cesare, J., Poleshko, A., Kiseleva, A. A., Truitt, R., Cardenas-Diaz, F. L., Zhang, X., Xie, X., Kotton, D. N., Alysandratos, K. D., Epstein, J. A., Shi, P. Y., Yang, W., … Korb, E. (2022). SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry. Nature, 610(7931), 381–388. https://doi.org/10.1038/s41586-022-05282-z Feierman, E. R., Paranjapye, A., Su, S., Qiu, Q., Wu, H., & Korb, E. (2024). Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling. bioRxiv : the preprint server for biology, 2024.11.01.620920. https://doi.org/10.1101/2024.11.01.620920   Related Episodes Neuroepigenetic Mechanisms and Primate Epigenome Evolution (Boyan Bonev) DNA Methylation Alterations in Neurodegenerative Diseases (Paula Desplats) The Role of Histone Dopaminylation and Serotinylation in Neuronal Plasticity (Ian Maze)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

No sabemos qué está pasando pero tampoco queríamos saltearnos esta fecha tan especial.

¡¡NUEVO PODCAST!!Dr. Eduardo Calixto…. “Autismo, TDAH y dislexia: origen neuronal”Luis Ignacio Santibáñez  y  Alexis Santibáñez…   “Papá e Hijo, el Podcast”Rodolfo Cadena Labrada… “Julio, el mes  de Frida”Armando Alberto León “El Salsariachi…  “Clásicos de Siempre”                                                                                                                       (Prince Royce y Enrique Guzmán)  

Astrocytes serve as crucial mediators of neuromodulatory processes previously attributed to direct communication between neurons, four new studies show.

www.mundofuturo.vip No podemos predecir el futuro pero sí podemos explorarlo. Jorge Alor, Mario Valle y Jaime Limón analizan las tendencias de tecnología e innovación que cambiarán al mundo en los próximos 10 años más de lo que ha cambiado en los últimos 100. /// Jorge Alor | @elpadrino Mario Valle | @bilbeny Jaime Limón | @mrlemon /// Learn more about your ad choices. Visit megaphone.fm/adchoices

En un mundo donde la velocidad del cambio supera nuestra capacidad de adaptación, entender cómo funciona el cerebro humano se ha convertido en una ventaja competitiva real para las empresas. El neuromanagement —o gestión basada en principios de neurociencia— no es una moda pasajera, sino una nueva forma de liderar desde el conocimiento científico del comportamiento humano. Esta disciplina propone algo tan disruptivo como lógico: alinear el funcionamiento del cerebro con la gestión empresarial para tomar mejores decisiones, liderar con más consciencia y crear organizaciones más resilientes.

ILEGALES: Yo soy quien espía los juegos de los niños CINERAMA: Reel 2, Dialogue 2 FREDDIE MERCURY: Love kills DARREN HAYMAN: You can't tell her anything EMILIO PERICOLI: Al di la SLEAFORD MODS: Tilldipper DREAM SEQÜENCE: Outside looking in ARSE: Primitive species PERCY FAITH: Since I fell for you SR CHINARRO: Una llamada a la acción PERTURBATOR: She's young, she is beauiful THINGS IN HERDS: Nothing is lost YO LA TENGO: Today is the day SONIC YOUTH: Eliminator Jr BONEY M: Belfast THE DEVIL MAKES THREE: All hail FRED NEIL: Everybody's talkin' RIDE: Kill switch THEY MIGHT BE GIANTS: The guitar MEN I TRUST: Paul's theme ISAAC ALBÉNIZ: Astúrias +Els Joves 1x04

¡¡ NUEVO PODCAST ‼ -Dr. Eduardo Calixto… “Ejercitarnos para mejorar la Conexión Neuronal”-Dr. Nathan Mansbach… “Yoga de la Risa: Día Mundial de la Risa (domingo 4 de mayo)”-Dra. Nelly Cecilia Capetillo Ventura. “Día Internacional contra el Bullying” (Acoso Escolar)-José Luis Cuevas (El Pintor)... Pelea del “Canelo” Álvarez contra el cubano William Scull-Héctor Ortiz… “Tributo a Jim Morrison y The Doors”    

uando todo se quedó a oscuras, solo quedaron tres cosas encendidas: ‑ una radio vieja, ‑ un par de micros prestados, ‑ y las ganas de rajar de tres miserables con más carajillo que rigor. En El Apagón te sentamos en la mesa pegajosa de un bar de pueblo donde estos “podcasters de fortuna” diseccionan —a su manera— el gran corte de luz que ha destapado lo frágil que es nuestra “sociedad ultraconectada”. Mientras la clase política naufraga en su propio maremagnum, nuestros veteranos tertulianos brindan con trifásicos y sentencias: ¿de verdad somos tan modernos si basta un chispazo para devolverte a la Edad de Piedra? Aviso al oyente: la fiabilidad de esta charla es la misma que la de un debate acalorado entre tres abuelos al filo del cierre del bar. Prepárate para ironía, morcilla y teorías conspiranoicas… o apaga y vámonos. Aquí tienes miseria en forma de links: https://linktr.ee/lagrimasenlalluvia ¿Quieres recibir los avisos de todos los programas? : https://t.me/lamiseriameencanta ¿ Te sientes miserier y quieres conocer a otros carnales? https://t.me/lamiseriameencantabidireccional ¿Te apetece inmortalizar tus miserias? lamiseriameencanta@gmail.com twitter @lagrimas_lluvia twitch: https://www.twitch.tv/lagrimasenlalluvia

Mapa cerebral detallado: Investigadores cartografían un milímetro cúbico de cerebro de ratón con 3,2 kilómetros de conexiones neuronales  Por Félix Riaño @LocutorCo Un equipo científico superó los límites de la neurociencia al mapear millones de sinapsis en un fragmento cerebral microscópico. En 1979, el Nobel Francis Crick consideró que era imposible descifrar la maraña interna de un minúsculo trozo de cerebro. Décadas después, más de cien expertos reunieron 1,6 petabytes de información para demostrar lo contrario. Han analizado un milímetro cúbico de tejido cerebral de ratón que contiene millones de sinapsis y más de 3 kilómetros de filamentos neuronales. Las imágenes en alta resolución, capturadas mediante microscopía electrónica y combinadas con inteligencia artificial, han abierto nuevas ventanas para comprender enfermedades como Alzheimer o Parkinson. Este nivel de detalle asombra, porque revela patrones de conexiones que antes eran un misterio. ¿Qué hallazgos van a descubrir luego con esta nueva cartografía? La complejidad neuronal también despierta dudas sobre su verdadero alcance El proyecto MICrONS tomó un milímetro cúbico del cerebro visual de un ratón y lo partió en unas 25.000 secciones. Cada sección fue fotografiada con microscopio electrónico para obtener una visión detallada de cada célula. Esos datos se combinaron con grabaciones de la actividad cerebral en vida, mientras el animal miraba videos y contenidos en una pantalla. Luego, expertos de Princeton organizaron toda esa información en un modelo tridimensional. Así, se obtuvo el mapa de cientos de miles de neuronas con millones de sinapsis, en un volumen del tamaño aproximado de un grano de arena. Estas redes neuronales se representan con tonos de colores vivos que muestran cada célula y cada circuito, como si fuera un bosque iluminado. La gran dificultad surge al querer entender cómo se comunican las neuronas en semejante densidad de conexiones. Cada célula envía impulsos eléctricos y sustancias químicas a cientos o miles de células vecinas. Aun con la tecnología disponible, es complicado detectar si una neurona establece un vínculo directo o si su señal pasa por varias estaciones intermedias. Además, surge la necesidad de corregir errores en el trazado automático de rutas neuronales. El volumen masivo de datos —que puede equivaler a 22 años de video HD ininterrumpido— requiere enormes recursos computacionales y trabajo humano para revisar y ajustar. Esto explica por qué Francis Crick pensó que era un reto inalcanzable. Los avances fueron posibles gracias a algoritmos de inteligencia artificial y a un arduo trabajo en equipo. La reconstrucción final de este milímetro cúbico de cerebro de ratón aporta evidencias sobre cómo las células inhibitorias y excitatorias se organizan. Estas últimas son responsables de encender la actividad neuronal, mientras que las inhibitorias se encargan de regular y refinar ese impulso. Se creía que las células inhibitorias funcionaban como un simple freno. Ahora, se sabe que eligen de manera muy precisa a qué neuronas controlar. Este entramado complejo, repleto de detalles microscópicos, se vuelve un banco de pruebas para las teorías del aprendizaje profundo en máquinas y abre caminos para entender enfermedades neuronales. Las conclusiones podrían brindar nuevas pistas sobre la conciencia, la inteligencia y los trastornos que interrumpen la comunicación interna del cerebro. Investigadores de prestigiosas instituciones afirman que esta cartografía digital es comparable al Proyecto Genoma Humano por su valor transformador. Todo indica que vamos a seguir aprendiendo mucho de esta región cerebral diminuta. La iniciativa surgió como parte del MICrONS Project, financiado por la agencia IARPA en Estados Unidos. Baylor College of Medicine recabó datos de actividad cerebral en ratones despiertos. El Allen Institute se encargó de cortar el tejido en láminas ultrafinas de unas 0,25 micrómetros de grosor (casi 1/400 del espesor de un cabello humano) para fotografiarlas. Princeton aplicó algoritmos de visión por computador y aprendizaje profundo para reconstruir la forma completa de cada neurona. Estos procedimientos crearon un gran desafío de administración de datos y versiones, ya que cada error de interpretación podía cambiar todo el resultado. Herramientas personalizadas de control de versiones y de corrección automatizada permitieron avanzar. Además, la presencia de imágenes funcionales y estructurales en el mismo conjunto de datos ofreció un panorama integral, permitiendo correlacionar actividad eléctrica real con conexiones anatómicas. Este enfoque sienta bases sólidas para futuras investigaciones que van a explorar circuitos aún más complejos. En este Flash Diario revisamos el logro de mapear un trozo de cerebro de ratón y observar millones de sinapsis. El avance ayuda a comprender cómo se conectan las células y a diagnosticar padecimientos neurológicos. Te invitamos a seguir nuestro pódcast en Spotify llamado Flash Diario para descubrir más noticias así de fascinantes.BibliografíaThe New York TimesThe TimesThe GuardianNatureConviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/flash-diario-de-el-siglo-21-es-hoy--5835407/support.

A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

Support this podcast at — https://redcircle.com/hypnosis-and-relaxation-sound-therapy9715/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

-Dr. Eduardo Calixto… La plasticidad neuronal que genera la proteína: BDNF.-Dr. Jorge Antonio Torres Martínez…Insuficiencia Venosa Crónica y Microangiopatia Diabética… ¿Qué relación guardan ambas enfermedades?- Gaby Pérez Islas… El duelo por los desaparecidos.-María Filippini. Actriz, cantante y bailarina… Reconocimiento a su trayectoria en el Teatro Silvia Pinal // Obra: La Chica del Bikini Azul.  

X y Elon Musk son noticia con el lanzamiento de Grok 3, un modelo de IA integrado en la red social que permite, entre otras cosas, monitorizar tendencias y la escucha social a través del seguimiento de la red. OpenAI lanza su nuevo modelo 4,5, un modelo que aventuramos puede ser clave en el desarrollo de algunas tecnologías emergentes... y Meta compite con Neuralink con una tecnología no invasiva que permite leer los pensamientos.

X y Elon Musk son noticia con el lanzamiento de Grok 3, un modelo de IA integrado en la red social que permite, entre otras cosas, monitorizar tendencias y la escucha social a través del seguimiento de la red. OpenAI lanza su nuevo modelo 4,5, un modelo que aventuramos puede ser clave en el desarrollo de algunas tecnologías emergentes... y Meta compite con Neuralink con una tecnología no invasiva que permite leer los pensamientos.

In this episode, we explore the alarming development of lab-grown human brain tissue that is being harnessed to operate machinery, play video games, and potentially more. Researchers are pushing the boundaries of biotechnology by cultivating miniature, functional clusters of neurons capable of interfacing with external devices. We also delve into Orchestrated Objective Reduction (Orch-OR), a theory of consciousness proposing that self-awareness arises from quantum-level processes within neuronal microtubules. Together, these cutting-edge topics raise profound questions about the nature of intelligence, the ethics of creating and using living brain matter, and the very foundations of conscious experience.

Have you ever finished a huge meal but still found room for dessert? Some people might talk about having a separate stomach for desserts. It turns out that your brain might be driving you to eat that sweet treat even though you don't 'need' it. Recent research in the journal Science found that the same nerve cells that signal 'you're full' also spark cravings for you wanting something sweet. Deep within a part of your brain called the hypothalamus are special cells known as pro-opiomelanocortin (POMC) neurons. They are well known for their role in telling us when we're full - however, these neurons have been found to have a surprising double life. When sugar enters your mouth, POMC neurons release natural opioids, like ß-endorphin, which trigger a rewarding sensation making us want more of the sugar even if our stomach is already full. The researchers found this out using experiments on mice. First, they bathed slices of mouse brain tissue in a fluorescent solution that binds to opioid receptors. They found that the highest density of these receptors was in a brain region known as the PVT, a key player in regulating feeding behaviours. This hinted at a direct link between the fullness signal and sugar cravings. They then let some lab mice eat their regular meal. After about 90 minutes, when the mice were clearly full, introduced a dessert of sugary food. Neuronal activity between the arcuate nucleus and the PVT spiked to nearly four times the level observed during the meal. Interestingly, this surge began before the mice even started eating the dessert, suggesting that the brain anticipates the sweet treat. To confirm this pathway, the scientists used a technique called optogenetics which uses light to control cells. When they inhibited the signals from the POMC neurons to the PVT, the mice consumed 40 percent less dessert. This confirmed that these satiety neurons, far from solely curbing appetite, also drive our desire for sugar when we're full. The researchers hypothesise that this might be evolutionary. Sugar was once a rare and quick source of energy and our brains evolved to seize opportunities when they come around, which may have meant eating more energy rich foods when you're already full. While sugar is now plentiful, that ancient wiring could still make us crave a sweet finish to our meals. Understanding that our dessert cravings have a neurological basis might help pave the way for new approaches to combat overeating and obesity. By targeting the specific brain pathways that drive sugar cravings, future treatments could help reduce excessive sugar consumption without dampening overall appetite. Next time you're tempted by that slice of cake after dinner, remember: it's not just a sweet tooth, it's your brain's finely tuned system working as it has for millennia. LISTEN ABOVESee omnystudio.com/listener for privacy information.

Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.

Genomics is about patterns, but finding them, or even knowing what to look for, is difficult. In this episode we talk to Noah Simon about the clever approaches he took to investigating the genomics of neuronal regeneration in mice. Hosted on Acast. See acast.com/privacy for more information.

In today's episode, we dive into the critical role of phospholipids in maintaining brain health, examining how these molecules contribute to neuronal communication, synaptic plasticity, and cognitive resilience. We'll explore the biochemical structure and function of key phospholipids like phosphatidylserine and phosphatidylcholine within neuronal membranes, where they play indispensable roles. We discuss associations and impacts of environmental toxins, aging, and neurodegenerative conditions. Finally, we discuss dietary tools to support phospholipid levels and promote cognitive health. Topics: 1. Introduction to Phospholipids and Cognitive Health 2. Brain Cell Structure and Composition - Neurons, glial cells. 3. Detailed Anatomy of Neurons - Soma contains organelles, dendrites receive signals, axon sends impulses. - Myelin sheath insulates axon, speeding signal transmission. - Myelin is rich in phospholipids. 4. Roles of Glial Cells in Brain Health - Astrocytes, oligodendrocytes, and microglia support neurons. - Glial cells regulate the brain's environment, form myelin, and provide immune defense. - Phospholipid-rich membranes are essential for glial function. 5. Biochemistry: Phospholipids - Phospholipids have a glycerol backbone, fatty acid tails, and a phosphate group. - Hydrophilic and hydrophobic parts form bilayers. - Key phospholipids: PC, PE, PS, PI 6. Phospholipid Bilayer's Role in Neuronal Communication - Ion channels, receptors, and transporters in the bilayer enable cell functions. - Ion channels allow ions to flow, creating signals for neuron communication. - Receptors detect neurotransmitters, initiating responses. 7. Neuronal Activation and Electrochemical Gradients - Resting neurons have ion concentration differences inside and outside the cell. - Ion channel activity during activation creates an action potential. - The phospholipid membrane enables controlled ion flow for signal transmission. 8. Neurotransmitter Release - Action potential at axon terminal triggers calcium entry. - Calcium causes vesicles to release neurotransmitters. - Released neurotransmitters bind to receptors, continuing the signal. 9. Diversity of Phospholipids in Neuronal Membranes - Different phospholipids (PC, PE, PS, PI) are essential for membrane integrity. 10. Summary: Phospholipids in Brain Function and Cognitive Health - Phospholipids support neuronal communication, synaptic plasticity, and cognitive resilience. - Synaptic plasticity - essential for learning and memory. 11. Phospholipid Disruption and Cognitive Decline - Oxidative stress, aging, and inflammation disrupt phospholipid composition. - Lipid peroxidation damages membranes, affecting neuron signaling. - Phospholipid damage contributes to cognitive decline. 12. Importance of Phospholipids in Aging and Brain Health - Lipid levels decrease with age, impacting brain function. 13. Environmental Toxins and the Brain - Heavy metals like mercury cause oxidative damage to phospholipids. - Damaged phospholipids and impaired neuron function. 14. Consequences of Suboptimal Phospholipids - Cognitive symptoms. - Low levels seen in neurodegenerative conditions. 15. Tools for Supporting Phospholipid Levels - Foods with PS and PC, such as fatty fish and eggs. - Phospholipid supplements. Thanks for tuning in! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

Dr. Joscha Bach discusses advanced AI, consciousness, and cognitive modeling. He presents consciousness as a virtual property emerging from self-organizing software patterns, challenging panpsychism and materialism. Bach introduces "Cyberanima," reinterpreting animism through information processing, viewing spirits as self-organizing software agents. He addresses limitations of current large language models and advocates for smaller, more efficient AI models capable of reasoning from first principles. Bach describes his work with Liquid AI on novel neural network architectures for improved expressiveness and efficiency. The interview covers AI's societal implications, including regulation challenges and impact on innovation. Bach argues for balancing oversight with technological progress, warning against overly restrictive regulations. Throughout, Bach frames consciousness, intelligence, and agency as emergent properties of complex information processing systems, proposing a computational framework for cognitive phenomena and reality. SPONSOR MESSAGE: DO YOU WANT WORK ON ARC with the MindsAI team (current ARC winners)? MLST is sponsored by Tufa Labs: Focus: ARC, LLMs, test-time-compute, active inference, system2 reasoning, and more. Future plans: Expanding to complex environments like Warcraft 2 and Starcraft 2. Interested? Apply for an ML research position: benjamin@tufa.ai TOC [00:00:00] 1.1 Consciousness and Intelligence in AI Development [00:07:44] 1.2 Agency, Intelligence, and Their Relationship to Physical Reality [00:13:36] 1.3 Virtual Patterns and Causal Structures in Consciousness [00:25:49] 1.4 Reinterpreting Concepts of God and Animism in Information Processing Terms [00:32:50] 1.5 Animism and Evolution as Competition Between Software Agents 2. Self-Organizing Systems and Cognitive Models in AI [00:37:59] 2.1 Consciousness as self-organizing software [00:45:49] 2.2 Critique of panpsychism and alternative views on consciousness [00:50:48] 2.3 Emergence of consciousness in complex systems [00:52:50] 2.4 Neuronal motivation and the origins of consciousness [00:56:47] 2.5 Coherence and Self-Organization in AI Systems 3. Advanced AI Architectures and Cognitive Processes [00:57:50] 3.1 Second-Order Software and Complex Mental Processes [01:01:05] 3.2 Collective Agency and Shared Values in AI [01:05:40] 3.3 Limitations of Current AI Agents and LLMs [01:06:40] 3.4 Liquid AI and Novel Neural Network Architectures [01:10:06] 3.5 AI Model Efficiency and Future Directions [01:19:00] 3.6 LLM Limitations and Internal State Representation 4. AI Regulation and Societal Impact [01:31:23] 4.1 AI Regulation and Societal Impact [01:49:50] 4.2 Open-Source AI and Industry Challenges Refs in shownotes and MP3 metadata Shownotes: https://www.dropbox.com/scl/fi/g28dosz19bzcfs5imrvbu/JoschaInterview.pdf?rlkey=s3y18jy192ktz6ogd7qtvry3d&st=10z7q7w9&dl=0

En Ivoox puedes encontrar sólo algunos de los audios de Mindalia. Para escuchar las 4 grabaciones diarias que publicamos entra en https://www.mindaliatelevision.com. Si deseas ver el vídeo perteneciente a este audio, pincha aquí: https://www.youtube.com/watch?v=E82ZKNv6rv0&t=2s En este encuentro hablaremos sobre los Estados de Ánimo que encontramos en la sociedad en estos tiempos intensos y cuál es la respuesta emocional y mental a todo lo que se está planteando para la Humanidad. También hablaremos de la parte biológica y los procedimientos que pueden ser de ayuda para apoyar a las personas a recuperar su centro. Alana Messineo Asesora en Bienestar Integral y Creación de Realidad. Formadora de Terapeutas en Desprogramación Neuronal. Elena Perea Nutricionista Ortomolecular. Especialista en tratamiento de candidiasis crónica, problemas digestivos e intestinales, hipotiroidismo y problemas hormonales a través de cambios en la dieta y suplementación natural. https://www.nutricionholistica.es/qui... / elenapereanutricionista https://www.elportaldealana.com https://t.me/+B1BUGT-hyoAxZTE0 Infórmate de todo el programa en: https://www.mindalia.com/television/ **CON PREGUNTAS AL FINAL DE LA CONFERENCIA PARA RESOLVER TUS DUDAS *** Si te parece interesante.... ¡COMPÁRTELO!! :-) ------------INFORMACIÓN SOBRE MINDALIA----------DPM Mindalia.com es una ONG internacional sin ánimo de lucro. Nuestra misión es la difusión universal de contenidos para la mejora de la consciencia espiritual, mental y física. -Apóyanos con tu donación en este enlace: https://streamelements.com/mindaliapl... -Colabora con el mundo suscribiéndote a este canal, dejándonos un comentario de energía positiva en nuestros vídeos y compartiéndolos. De esta forma, este conocimiento llegará a mucha más gente. - Sitio web: https://www.mindalia.com - Facebook: / mindalia.ayuda - Instagram: / mindalia_com - Twitch: / mindaliacom - Vaughn: https://vaughn.live/mindalia - Odysee: https://odysee.com/@Mindalia.com *Mindalia.com no se hace responsable de las opiniones vertidas en este vídeo, ni necesariamente participa de ellas. *Mindalia.com no se responsabiliza de la fiabilidad de las informaciones de este vídeo, cualquiera sea su origen. *Este vídeo es exclusivamente informativo.

Medita, piensa y encuentra la salida de esa cárcel, del sueño….

El especialista abordó las enfermedades como el Párkinson y el Alzheimer, que están en el “top 5” de las principales causas de muerte en Chile

In this episode, we explore the intricacies of neuronal communication, delving into how neurons transmit signals through synaptic connections using neurotransmitters like glutamate and GABA. We also examine the effects of neurotoxins, such as heavy metals and environmental pollutants, on these critical synaptic pathways, leading to cognitive and neurological impairments. Lastly, we discuss neuroprotective strategies to mitigate neurotoxin exposure and promote optimal brain health. Topics: 1. Overview of Brain Cell Anatomy - Types of brain cells: neurons and glial cells. - Structure of neurons: - Soma (cell body): contains nucleus and organelles. - Dendrites: receive signals from other neurons. - Axon: transmits electrical impulses away from the soma. - Synaptic terminals: form synapses with target cells. 2. Neuronal Communication - Synapse structure: - Presynaptic terminal. - Synaptic cleft. - Postsynaptic membrane. - Neurotransmitters: - Role in neuronal communication. - Excitatory neurotransmitters (e.g., glutamate). - Inhibitory neurotransmitters (e.g., GABA). 3. Summary of Neuronal Communication - Recap of excitatory and inhibitory neurotransmitters. - Importance of maintaining proper neuronal communication. 4. Neurotoxins and Their Effects - Types of neurotoxins: - Heavy metals (e.g., lead, mercury, arsenic, cadmium, aluminum). - Chemical neurotoxins (e.g., organophosphates, solvents). - Biological toxins (e.g., mycotoxins). - Environmental pollutants (e.g., PCBs, dioxins). - Mechanisms of neurotoxin damage: - Disruption of neurotransmitter release. - Impairment of receptor function. - Interference with ion channel operation. 5. Example: Mercury's Impact on Cognitive Function - Pathway of mercury exposure and accumulation in the brain. - Disruption of calcium homeostasis and synaptic transmission. - Resulting cognitive impairments. 6. Strategies to Reduce Neurotoxin Exposure - Nutrition: - Opting for organic produce. - Washing produce properly. - Avoiding MSG and aspartame. - Limiting aluminum exposure (baking powder). - Evaluating cookware. - Avoiding farmed salmon. - Water and air quality: - Using water filtration to remove fluoride. - Choosing fluoride-free toothpaste. - Improving air quality and mold remediation. - Using air-purifying plants (e.g., aloe vera, English ivy). - Reducing exposure to places with highly-concentrated neurotoxic chemicals (e.g., nail salons). Thank you to our episode sponsor: ⁠⁠⁠Tremetes, LLC⁠ Use code CHLOE15 to get 15% off ⁠Tremetes' Turkey Tail⁠ Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

En este episodio hablamos sobre como el cerebro de papá cambia al ser padreUnete todos los Martes en nuestras reuniones en vivo por zoom. Mandanos un whatsapp para mas información: 323-365-5717

Keshov Sharma and Lizabeth Romanski discuss their paper, “Neuronal Population Encoding of Identity in Primate Prefrontal Cortex,” published in Vol. 44, Issue 6 of JNeurosci, with Editor-in-Chief Cabine Kastner. Find our upcoming webinar schedule here. With special guests: Keshov Sharma and Lizabeth Romanski Hosted by: Sabine Kastner On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system.  Find out more about SfN and connect with us on X, Instagram, and LinkedIn. 

For many years, Parkinson's disease and dementia with Lewy bodies have been defined using clinical features. With recent advances in biomarkers, particularly the alpha-synuclein seed amplification assay that allows us to detect misfolded and aggregated alpha-synuclein in cerebrospinal fluid, it is now possible to identify the presence of pathological neuronal alpha-synuclein in living patients. With input from diverse stakeholders, a new biological definition of neuronal alpha-synuclein disease (NSD) has been proposed, along with an integrated staging system (NSD-ISS). In this interview, we discuss the development of this biologic definition for Parkinson's disease and the staging system with Dr. Lana Chanine, one of the lead authors of the recently published manuscript in The Lancet Neurology that describes this work. It is important to note that the NSD and NSD-ISS are for research purposes only right now, and they are not ready to be implemented in the clinic. Lana is a Movement Disorders Neurologist and Associate Professor of Neurology at the University of Pittsburgh.This podcast is geared toward researchers and clinicians. If you live with Parkinson's or have a friend or family member with PD, listen to The Michael J. Fox Foundation Parkinson's Podcast. Hear from scientists, doctors and people with Parkinson's on different aspects of life with the disease as well as research toward treatment breakthroughs at https://www.michaeljfox.org/podcasts.

For many years, Parkinson's disease and dementia with Lewy bodies have been defined using clinical features. With recent advances in biomarkers, particularly the alpha-synuclein seed amplification assay that allows us to detect misfolded and aggregated alpha-synuclein in cerebrospinal fluid, it is now possible to identify the presence of pathological neuronal alpha-synuclein in living patients. With input from diverse stakeholders, a new biological definition of neuronal alpha-synuclein disease (NSD) has been proposed, along with an integrated staging system (NSD-ISS). In this interview, we discuss the development of this biologic definition for Parkinson's disease and the staging system with Dr. Lana Chanine, one of the lead authors of the recently published manuscript in The Lancet Neurology that describes this work. It is important to note that the NSD and NSD-ISS are for research purposes only right now, and they are not ready to be implemented in the clinic. Lana is a Movement Disorders Neurologist and Associate Professor of Neurology at the University of Pittsburgh.This podcast is geared toward researchers and clinicians. If you live with Parkinson's or have a friend or family member with PD, listen to The Michael J. Fox Foundation Parkinson's Podcast. Hear from scientists, doctors and people with Parkinson's on different aspects of life with the disease as well as research toward treatment breakthroughs at https://www.michaeljfox.org/podcasts.

TWiN explains research showing that interaction between glioma cells and neurons in the brain shares mechanistic features with synaptic plasticity that contributes to memory and learning in the healthy brain.  Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Glioma synapses recruit mechanisms of adaptive plasticity (Nature) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv

En Ivoox puedes encontrar sólo algunos de los audios de Mindalia. Para escuchar las 4 grabaciones diarias que publicamos entra en https://www.mindaliatelevision.com. Si deseas ver el vídeo perteneciente a este audio, pincha aquí: https://www.youtube.com/watch?v=1saNZ0Wl9eY Hablaremos sobre el Glutatión y su influencia en la consciencia corporal y los estados de ánimo. Entiende cómo, la falta de esta molécula fundamental que el cuerpo mismo produce, genera ansiedad, depresión o ataques de pánico y descubre cómo apoyar al cuerpo a salir de estos estados de ánimo debilitantes y subir la frecuencia. Alana Messineo Asesora en Bienestar Integral y Creación de Realidad. Formadora de Terapeutas en Desprogramación Neuronal. Elena Perea Nutricionista Ortomolecular. Especialista en tratamiento de candidiasis crónica, problemas digestivos e intestinales, hipotiroidismo y problemas hormonales a través de cambios en la dieta y suplementación natural. https://www.nutricionholistica.es/qui... https://www.instagram.com/elenaperean... https://www.elportaldealana.com https://t.me/+B1BUGT-hyoAxZTE0 Infórmate de todo el programa en: http://television.mindalia.com/catego... **CON PREGUNTAS AL FINAL DE LA CONFERENCIA PARA RESOLVER TUS DUDAS *** Si te parece interesante.... ¡COMPÁRTELO!! :-) ------------INFORMACIÓN SOBRE MINDALIA----------DPM Mindalia.com es una ONG internacional sin ánimo de lucro. Nuestra misión es la difusión universal de contenidos para la mejora de la consciencia espiritual, mental y física. -Apóyanos con tu donación en este enlace: https://streamelements.com/mindaliapl... -Colabora con el mundo suscribiéndote a este canal, dejándonos un comentario de energía positiva en nuestros vídeos y compartiéndolos. De esta forma, este conocimiento llegará a mucha más gente. - Sitio web: https://www.mindalia.com - Facebook: https://www.facebook.com/mindalia.ayuda/ - Instagram: https://www.instagram.com/mindalia_com/ - Twitch: https://www.twitch.tv/mindaliacom - Vaughn: https://vaughn.live/mindalia - Odysee: https://odysee.com/@Mindalia.com *Mindalia.com no se hace responsable de las opiniones vertidas en este vídeo, ni necesariamente participa de ellas. *Mindalia.com no se responsabiliza de la fiabilidad de las informaciones de este vídeo, cualquiera sea su origen. *Este vídeo es exclusivamente informativo.

All of us have the power and choice to re-architect the structure of our brain to be healthier, happier and of greater service. Discussed in this fascinating interview episode with award winning author & TED Talk speaker, Shauna Shapiro, are the differences between meditation and mindfulness, empathy and compassion, and how to leverage all of these concepts into our day-to-day lives. To embody practices, we have to understand them and science helps us with this. You will learn in this episode: How what you practice grows Why your attention is your greatest currency  How the understanding of neuroplasticity in science has changed everything How mindfulness and meditative practices positively impact every sector of your life The difference between meditation and mindfulness (because they are different!) How these practices make you a better citizen and family member Why compassion is more advantageous than empathy  Why compassion for yourself is crucial  SHOW NOTES: The art of attention is discussed. Your attention is your greatest currency. Your attention implicates every arena of your life: the quality of your  Neuroplasticity is the capacity at any age to reconfigure our brain and its thought patterns. How to rewire your mind: Neuroplasticity & spirituality   All of us have the power and choice to re-architect the structure of our brain to be healthier, happier to be of greater service. What we practice grows stronger both for the good and for the bad.  Neuronal pruning concepts are detailed such as pruning neural pathways. Every time you go on new pathway it prunes automatically prunes the old pathway  Difference between meditation and mindfulness is broken down. They are distinct and separate things that support each other. Meditation is the practice and exercise so we can grow mindfulness. It's going to the gym, so we can grow our mindfulness which is a state, a way of being and a way of paying attention. Attention is your most valuable resource. Ask yourself, can I be present? On average a Harvard study shows, our minds wander 47% of the time! So most of us are missing pretty much half our lives. Meditation is part of practice so we can grow our mindfulness in moment-to-moment life. This model of mindfulness is detailed with clear steps to use.  Many people feel they can't meditate.  The many benefits of meditation are discussed. So many of us don't feel worthy of taking time to care for ourselves. These practices are self-love practices.People who practice mindfulness and meditation are better citizens of the world. The myth that meditation and mindfulness practices are selfish is debunked with science.They make people more generous and more compassionate. There is data to prove this. The science is very compelling.  The convergence and confluence of the feelings of compassion and empathy are broken down. To embody practices, we have to understand them and science helps us with this. The ways that empathy and compassion work in our brain are discussed and then how to leverage these feelings in impactful ways are detailed. The Tibetan definition of compassion is considered incomplete if it does not include ourselves. Furthermore, a compassionate act that is not healthy for you, is not even considered compassion. ✨HUGE ANNOUNCEMENT!:  The doors for the Modern Mystic Membership are now open! Monthly Mystic Members get access to a library of over 100 tantric yoga, meditation & breathwork classes as well as short “Mystic Hack” videos which have topics including astrology, tarot cards, developing psychic abilities, grounding/protecting/growing your energy and more! Sampling of FREE videos on the elegant Mystic Membership platform:  modernmystic.love ✨I offer profound psychic medium readings modernmystic.love ✨I offer one-on-one  Soul Psyche Mapping Astrology Readings. Book via (*This includes a copy of your birth chart and an audio recording of the session) modernmystic.love ✨Give it a 5 star, 1 line review on Apple Music (takes literally 2 min either from an iPhone or via the Apple Music store on all other devices) or on Spotify. This is HUGE as it helps get it heard more which supports the podcast. ✨Join conscious conversation & community in the Modern Mystic Podcast Private F-book Group: https://www.facebook.com/groups/959629444823656/ ✨Get inspiring insights on IG: @modernmysticlove @mystickilkenny

Synopsis: Mark Litton, Ph.D., is the President and CEO of Athira Pharma, a late clinical-stage biopharmaceutical company focused on developing small molecules to restore neuronal health and slow neurodegeneration for those suffering from Alzheimer's, Parkinson's disease, dementia, and more. Mark talks about being a CEO for the first time and what he's learned. He discusses how the biotech ecosystem and its ability to raise capital for companies has changed over the last couple of years and how that's informing how he's operating at Athira. He talks about fundraising strategy and how he communicates with team members who perhaps haven't been involved in fundraising cycles and value creation at biotech before. Finally, he shares how he thinks about business development and his approach to partnerships. Biography: Mark is President and CEO of Athira Pharma, a position he has held since October 2021. Previously, he served as Athira's COO since July 2019. Prior to joining Athira, Mark served as the President and COO of Alpine Immune Sciences, Inc. Prior to that he spent more than 14 years at Alder Biopharmaceutical Inc., a publicly traded biopharmaceutical company, which was acquired by Lundbeck A/S. As co-founder and CBO, Mark helped build the business and oversaw finance, investor relations, deal making, business development, alliance management, human resources, and overall corporate strategy. While at Alder, Mark was directly responsible for raising over ~$1B in equity capital and led negotiations for numerous corporate alliances between biotech and pharmaceutical companies. Mark has a PhD in immunology from Stockholm University, an MBA from Santa Clara University and a BA in Biochemistry and Molecular Biology from UC Santa Cruz.

En este nuevo episodio de Encuentro, hablamos con el Doctor en Física, Jose Luis Mateos. Él es un investigador de la Universidad Nacional Autónoma de México (UNAM) enfocado en Sistemas Complejos y sus diversas aplicaciones, entre ellas la sismología, la epidemiología, la sociología, la neurociencia, los sistemas computacionales y las finanzas. Hablamos sobre el caos y su estudio a través de modelos probabilísticos y cómo esto se puede aplicar al mundo de las inversiones y los black swans. Jose Luis también nos platica del surgimiento de la inteligencia artificial generativa y lo que los sistemas complejos nos pueden enseñar de su relevancia tecnológica para hoy y el futuro.

Today, I am blessed to have here with me Dr Chris Palmer. He received his medical degree from Washington University School of Medicine and did his internship and psychiatry residency at McLean Hospital, Massachusetts General Hospital, and Harvard Medical School. Dr. Palmer leads McLean Hospital's Department of Postgraduate and Continuing Education. In this role, he has developed hundreds of educational conferences, workshops, Grand Rounds, and other professional educational activities, most of them under the aegis of Harvard Medical School. His leadership has transformed the department from a small, subsidized department of the hospital into a flourishing educational program that is now leading mental health education for professionals nationwide. He has held numerous leadership positions in the continuing education field beyond McLean Hospital's program, including serving on leadership, advisory, and strategic planning committees of Harvard Medical School, Partners Healthcare, the Massachusetts Medical Society, and the Accreditation Council for Continuing Medical Education (ACCME). In this episode, Dr. Palmer will delve into various topics including nicotine's effects on mitochondrial function, the cell danger response and its relationship with mitochondria, the impact of stressors on mitochondrial responses, variations in mitochondrial responses among different tissues and cell types, and the concept of energy allocation and optimization within the body's systems. Tune in as we chat about the relationship of Ketogenic Diet and overall health. Join my 90 day heavy metals detox program (6 spots left) http://www.ketokampdetox.com  Order Keto Flex: http://www.ketoflexbook.com -------------------------------------------------------- Download your FREE Vegetable Oil Allergy Card here: https://onlineoffer.lpages.co/vegetable-oil-allergy-card-download/ / / E P I S O D E   S P ON S O R S  Wild Pastures: $20 OFF per Box for Life + Free Shipping for Life + $15 OFF your 1st Box! https://wildpastures.com/promos/save-20-for-life-lf?oid=6&affid=132&source_id=podcast&sub1=ad BonCharge: Blue light Blocking Glasses, Red Light Therapy, Sauna Blankets & More. Visit https://boncharge.com/pages/ketokamp and use the coupon code KETOKAMP for 15% off your order.  Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. [03:22] The Transformative Power of the Ketogenic Diet in Mental Health Long-term adherence to a ketogenic diet can lead to significant health improvements. The ketogenic diet has shown potential in improving mental health conditions such as schizophrenia and bipolar disorder. Weight loss goals can serve as a powerful motivator for individuals with mental health challenges to embark on dietary changes. The ketogenic diet has the potential to reduce symptoms such as hallucinations, delusions, and paranoia in certain individuals. The success of the ketogenic diet in mental health has sparked scientific research and clinical trials, positioning it as a promising approach in the field of neuroscience. [13:08] Mitochondria: Its Intricate Role in Mental Health Mitochondria, often known as the powerhouse of the cell, have far-reaching functions beyond energy production. Mitochondria play critical roles in the functioning of cells, including tasks relevant to mental health. High mitochondrial concentration is observed at synapses, the communication points between neurons. Mitochondria actively contribute to neurotransmitter release and the restoration of ion gradients at synapses. Disruption of mitochondrial function at synapses can impair neurotransmitter release and impact mental health. [21:16] Mitochondrial Dysfunction and Dietary Impact on Health Mitochondrial dysfunction, characterized by oxidative stress, can lead to cell death. The standard American diet high in processed carbs and seed oils may contribute to mitochondrial dysfunction. Adopting a low-carb, high-fat ketogenic diet or practicing fasting can stimulate mitochondrial adaptation and improvement. Fasting and ketogenic diet trigger autophagy, a process that removes defective proteins and promotes cellular renewal. Mitochondrial biogenesis occurs during fasting or a ketogenic diet, leading to an increase in healthy mitochondria and potentially benefiting both metabolic and mental health. [29:20] Mitochondrial Dysfunction and Neuronal Vulnerability Malfunctioning mitochondria struggle to process fuel sources, leading to insufficient ATP production and cellular dysfunction. Glycolysis becomes the alternative energy pathway in cells with dysfunctional mitochondria, resulting in lactic acid buildup and further impairments. Excessive reactive oxygen species exacerbate the cellular struggles, leading to apoptosis in most cells but posing challenges in neurons. Neurons lack programmed cell death (apoptosis) and rely on protective mechanisms, making them highly vulnerable to oxidative stress. Neuronal death and shrinkage can contribute to neurodegenerative disorders like Alzheimer's and Parkinson's disease. [50:14] Nicotine's Effects on Mitochondria and the Cell Danger Response Nicotine, as a stimulant, can enhance mitochondrial function in low doses, potentially improving mood, cognition, and memory. Pure nicotine can be beneficial if used appropriately and in moderation, but excessive use or underlying health issues can lead to harm. Mitochondria play a role in the cell danger response, where they adjust energy production based on perceived threats, such as infections or stressors. Mitochondrial responses to stressors vary among different tissues and cell types, with some increasing energy production and others reducing it. The body constantly reallocates energy resources to optimize overall function, guided by complex coordination between cells, mitochondria, and the nervous system. AND MUCH MORE! Resources from this episode:  Website: https://www.chrispalmermd.com/  Get Dr Palmer's brand new book Brain Energy here: https://amzn.to/3ppQQCH Free Newsletter: https://brainenergy.com/  Follow Dr Palmer Facebook: https://www.facebook.com/ChrisPalmerMD/  Twitter: https://twitter.com/ChrisPalmerMD/  YouTube: https://www.youtube.com/@chrispalmermd4244  Instagram: https://www.instagram.com/chrispalmermd/  Join the Keto Kamp Academy: https://ketokampacademy.com/7-day-trial-a Watch Keto Kamp on YouTube: https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ Join my 90 day heavy metals detox program (6 spots left) http://www.ketokampdetox.com  FREE DETOX TRAINING: https://www.ketokamp.com/Detox-Masterclass Order Keto Flex: http://www.ketoflexbook.com -------------------------------------------------------- Download your FREE Vegetable Oil Allergy Card here: https://onlineoffer.lpages.co/vegetable-oil-allergy-card-download/ / / E P I S O D E   S P ON S O R S  Wild Pastures: $20 OFF per Box for Life + Free Shipping for Life + $15 OFF your 1st Box! https://wildpastures.com/promos/save-20-for-life-lf?oid=6&affid=132&source_id=podcast&sub1=ad BonCharge: Blue light Blocking Glasses, Red Light Therapy, Sauna Blankets & More. Visit https://boncharge.com/pages/ketokamp and use the coupon code KETOKAMP for 15% off your order.  Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. // F O L L O W ▸ instagram | @thebenazadi | http://bit.ly/2B1NXKW ▸ facebook | /thebenazadi | http://bit.ly/2BVvvW6 ▸ twitter | @thebenazadi http://bit.ly/2USE0so ▸ tiktok | @thebenazadi https://www.tiktok.com/@thebenazadi Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility of statements made by guests. This podcast does not make any representations or warranties about guests qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.