Podcasts about mitochondrial

ReferencesHepatology.2023 Apr 17;77(5):1654–1669Oncotarget.2017 Aug 22; 8(34): 55967–55983.Can.J.Physiol.Pharmacol. 2025. 103: 208–224 Guerra. DJ 2025. Unpublished LecturesPage, J. 1970 Tangerine LZhttps://music.youtube.com/watch?v=_0Auvlsv860&si=A4mSuCcSwCeF0M4DLennon./McCartney/Harrison. 1966. Rubber Soul lphttps://music.youtube.com/playlist?list=OLAK5uy_lirCIxLpU2odTVLZ_Sbo1wZaeu5IStivs&si=HmFiZGPpBWuz14im Biber , HI. !681 Sonata & in G major C.144https://music.youtube.com/watch?v=kFOD7qM1oNc&si=OiHaskXRsDRbcUDz

This episode covers mitochondrial inheritance.Written notes can be found at https://zerotofinals.com/paediatrics/genetics/mitochondrialinheritance/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

ReferencesPLOS One 2014ovember25, https://doi.org/10.1371/journal.pone.0113939Int J Mol Sci. 2019 Mar; 20(5): 1223.Front Endocrinol (Lausanne). 2023 Feb 7;14:1085041Biomolecules.2021 Dec31;12(1):56. Lake, G. 1972. From The Beginning ELPhttps://music.youtube.com/watch?v=hsJ9YXHqnr8&si=jOAgixfiDxqknPVS

Chronic disease now affects 76 percent of American adults, which shows a widening gap between higher healthcare spending and worsening national health. In this episode, I sit down with Dr. Chris Turnpaugh to explore why the United States has become so chronically ill and why our current medical model, which excels in acute care, struggles with long-term metabolic and inflammatory conditions. Our discussion focuses on the need for a proactive healthcare system that identifies early patterns instead of waiting for disease to reach a crisis point. We talk about the limitations of traditional blood tests, the importance of understanding subtle dysfunction before it becomes pathology, and how lifestyle and environmental factors shape the progression of chronic illness. Early recognition and root-cause medicine form the foundation of better health outcomes. We also highlight emerging tools that are transforming integrative care, including functional peptides like BPC157 and strategies that support mitochondrial health and cellular energy. Dr. Turnpaugh offers a clear and practical perspective on how healthcare can evolve to improve vitality and help patients thrive throughout the chronic disease era.   Key takeaways: The U.S. healthcare system needs to transition from reactive sick care to proactive chronic disease management to address the country's worsening health statistics. Identifying disease patterns and root causes early-on can prevent full-blown diagnoses and improve patient outcomes. Functional peptides such as BPC157 and the role of inflammation management can significantly impact recovery from musculoskeletal and chronic conditions. Integrated health practices that combine multiple disciplines and focus on the whole person are essential for effective treatment and patient care. Mitochondrial health is crucial for overall wellbeing, influencing everything from chronic disease risk to cognitive health. More About Dr. Chris Turnpaugh:   Dr. Chris Turnpaugh is the Founder and Clinic Director of Turnpaugh Health and Wellness Center, where he leads a team of over 20 clinicians in a collaborative care setting. A pioneering force in functional and integrative medicine, he brings more than two decades of clinical expertise, innovation, and leadership to the field. His unique approach blends the art of healing with the science of systems biology through the principles of functional medicine, always with a focus on identifying and addressing the root cause of disease. Dr. Turnpaugh graduated from Life University and completed his post-doctorate in functional neurology. His passion for functional medicine was sparked in 1995 after attending a seminar with Dr. Jeffrey Bland, the father of functional medicine, while seeking ways to help a patient living with ALS. Inspired by the promise of root cause medicine, he opened the Turnpaugh Health and Wellness Center in 1999. With extensive experience supporting patients facing complex, chronic, autoimmune, and neurological conditions—including Lyme disease, thyroid and hormonal disorders—Dr. Turnpaugh is recognized for his compassionate, whole-person approach. He thrives on the care team model, sharing knowledge not only with patients and colleagues, but also with providers across the country, teaching on topics such as blood chemistry, thyroid conditions, and brain health. Website Instagram Facebook Connect with me! Website Instagram Facebook YouTube

Your muscle isn't just for strength—it's your metabolic organ, your glucose sink, your hormonal stabilizer, and your anti-aging insurance policy. But here's the hard truth: If your protein is low in leucine, hard to digest, or blocked by anti-nutrients, you're putting the brakes on everything you're trying to optimize.

ReferencesGuerra, DJ.2025. Unpublished LecturesHepatology.2023 Apr 17;77(5):1654–1669Comprehensive Gut Microbiota2022, Pages 201-219Dylan, B. 1964. My Back Pages. Byrdshttps://music.youtube.com/watch?v=OADlrLHfYW4&si=Q63xZIE_33GXVYv4

ReferencesMol Immunol. 2017 Apr 1;87:1–11Guerra, DJ 2025 Unpublished LecturesHayward/Pinder/Lodge/Thomas. 1967. Days of Future Passed. Moody Blues.https://music.youtube.com/playlist?list=OLAK5uy_l2x8IxcSnnBm21QUI3aKwu7Sz8thfM-1w&si=9tsIhVrSdLrMn7vG

Send us a textIn this powerful & eye-opening conversation, Vanessa & Heather explore the modern fertility crisis through a truly holistic lens—blending circadian biology, environmental medicine, nervous system health, hormonal resilience, and the profound healing potential of classical homeopathy. They uncover the hidden forces quietly reshaping reproductive health today: • artificial light and disrupted circadian rhythms • endocrine disruptors in food, water, and personal care products • chronic stress, trauma imprints, and dysregulated nervous systems • nutrient depletion and mitochondrial dysfunction • toxic environmental exposures and chemical overload • the over-medicalization of women's bodies and intuitionThey also explore how homeopathy can help restore the terrain—supporting fertility by regulating the nervous system, balancing hormones, clearing inherited patterns, detoxifying environmental burdens, helping the body reconnect with its innate intelligence.This conversation reframes fertility not as a symptom to “fix,” but as a profound expression of safety, nourishment, mitochondrial vitality, and soul alignment.Women learn that fertility struggles are not their fault—they are the result of living in a world that has pulled us out of nature, out of rhythm, out of our own bodies.Vanessa shares insights from her Women's Homeopathy Course, a powerful journey that supports women in understanding their constitution, healing emotional imprints, navigating hormonal shifts, and using homeopathic remedies with confidence for themselves/their families.A must-listen for anyone seeking holistic hormonal support, deeper self-care, and a grounded path toward natural conception—rooted in biology, energy, and the wisdom of the feminine. Women's Homeopathy Course Link: https://0fbe4769-fb62-4dbf-a141-982c836b0942.paylinks.godaddy.com/HomeopathywomenSupport the showFind Heather:https://calendly.com/enlightenedmoodhttps://www.instagram.com/enlightenedmood/Discount codes:https://www.vivarays.com ➡️ Code: enlightenedmood.comhttps://midwestredlighttherapy.com/affiliate/enlightenedmood/ https://www.emr-tek.com/enlightenedmood ➡️ Code: enlightenedmood Find Vanessa:https://instagram.com/bright_light_wellness/vanessabaldwin/https://www.instagram.com/healingfamilieswithhomeopathy/Website: https://brightlightwellnesscoach.com/Discount codes:https://midwestredlighttherapy.com/ ➡️ Code: Brightlightwellnesshttps://vivarays.com/ ➡️ Code: Brightlightwellness...

ReferencesGuerra, DJ.2025 Unpublished LecturesHepatology.2023 Feb 9;78(3):878–895.Mozart, WA. Mass in C Minor, K, 427https://music.youtube.com/watch?v=Ez0kqVShFEs&si=D1MUVoXZIbPxRyM4

Get access to more than 200 episodes of my premium podcast (The Aliquot) when you sign up as a FoundMyFitness Premium Member Download my "How to Train According to the Experts" guide One minute of vigorous exercise may be worth up to ten minutes of "moderate" cardio for extending lifespan and preventing chronic disease. In this Journal Club episode, Rhonda Patrick, PhD and endurance athlete Brady Holmer dissect a new Nature Communications study of more than 70,000 adults showing that vigorous intensity is roughly 4–10x more potent than moderate activity for reducing all-cause mortality, cardiovascular events, type 2 diabetes, and cancer outcomes—far beyond the long-standing 1:2 rule embedded in global exercise guidelines. Timestamps: (00:00) Introduction (07:01) What exactly is the 1:2 rule for exercise intensity? (08:18) Calorie burn vs. longevity—origins of the 1:2 rule (11:15) What counts as 'vigorous' exercise, really? (13:35) Where the exercise guidelines fall short (14:19) Can your wearable predict disease risk years in advance? (20:11) Is vigorous activity easier to achieve than people think? (22:47) How researchers avoided the 'healthy user bias' (23:59) Health equivalence ratio—a better way to measure exercise benefits? (25:45) Is vigorous exercise truly 4–10x more effective? (29:55) Can one vigorous minute match an hour of gentle walking? (32:02) Why vigorous activity—not gentle—offers dose-dependent benefits (33:50) Is vigorous exercise 5x better at preventing heart attacks & strokes? (34:24) Why vigorous activity stands out for cancer prevention (34:59) Does zone 2 qualify as vigorous exercise? (36:11) Dose-response comparison—vigorous vs. moderate vs. light activity (37:22) Is vigorous exercise the secret to younger arteries? (43:15) Why aging hearts need intensity (46:09) Can vigorous exercise halt your VO₂ max decline? (47:26) Why moderate exercise alone might not improve VO₂ max (49:21) Is vigorous exercise 10x more powerful at preventing diabetes? (55:48) Mitochondrial biogenesis—why intensity is essential (58:40) Can you directly measure mitochondrial health? (1:00:57) Does vigorous exercise kill circulating tumor cells? (1:07:15) Why vigorous intensity triggers beneficial hormone changes (1:08:05) Can vigorous activity protect older adults from falls? (1:12:36) Does vigorous exercise combat inflammation? (1:14:29) Is high-intensity training the key to a younger brain? (1:16:01) Is vigorous exercise more powerful than we realized? (1:17:50) Can the benefits of vigorous exercise fit into a pill? (1:19:08) How small doses of intensity might extend your lifespan (1:23:15) Do short bursts of vigorous movement match full workouts? (1:27:26) Why your wearable might undervalue short vigorous bouts (1:30:06) Can planned micro-workouts replace traditional gym sessions? (1:35:10) Why exercise guidelines urgently need updating (1:46:35) Does light activity still offer real benefits? (1:49:04) Is vigorous exercise safe for older adults? (1:53:28) Are high-intensity workouts detrimental to female hormones? (1:58:02) Safe vigorous exercise options—even with chronic illness (1:59:05) The 80/20 rule for balancing intensity and recovery (2:01:30) Inside Brady's routine—how much vigorous exercise is optimal? (2:05:17) Can vigorous activity boost kids' brainpower (and grades)? (2:08:14) Are we significantly underestimating vigorous exercise benefits? (2:10:03) Why chasing steps isn't the answer Show notes are available by clicking here Watch this episode on YouTube

ReferencesHepatology.2023 Feb 9;78(3):878–895.Mozart, WA. 1791. Ave Verum Corpus. K618https://music.youtube.com/watch?v=Z-xMjO0d-pc&si=g1TpOohQQt9forf0Murray, J. 1874 Jolly Old St Nicholas. Instrumentalhttps://music.youtube.com/watch?v=eTHdEA5zh2Q&si=0v0ADs7LhtIu7zqd

Episode Summary In our newest episode, we join roving reporter Kat Bolstad at the Cephalopod International Advisory Council in Okinawa and hear from some of the most interesting people in Cephalopod research.    Check out our lovely new website where you can find more detailed notes, images and links to the wider reading. In this episode… Welcome back to the Deep-Sea Podcast, your punk take on all things deep sea!  The Professor is still down under, organizing conferences and recuperating from Old Mate's Classic Aussie Sausage Sizzle, a robust event filled with friends of the podcast and still felt 24 hours later.    Thom is freshly back from another big ocean/small boat adventure, in which the ocean always wins and his stomach always loses… everything. He is also stretching his creative muscles and curating an exciting new museum exhibit called Breathe | Mauri Ora at Te Papa, an examination of science into art by Marshmallow Lazer Feast.    Our episode this month is a fascinating collection of interviews from the Cephalopod International Advisory Council Meeting that took place Oct-Nov in Okinawa Japan. Join Kat Bolstad, our roving reporter, as she takes time between bug hunting, seeing her first wild cuttlefish and shaking hands with a new octopus friend to collect interviews with some of the coolest names in Ceph science with a focus on the deep-sea. We hear from 12 Cephalopod experts on a wide variety of topics, including the preferred snacks for cephalopods, the effects of oxygen depletion on egg hatching, water temperature and acidification effects on cephalopod populations, and of course, the correct answer to the viral question: are octopuses actually ALIENS?   In the news, get ready for updates on: Deep diving manta rays using the ocean bottom to navigate A newly launched AI tool to map the Deep- Sea Bright blue mud filled with fat molecules indicating life in the deep Corals and Crinoids sharing symbionts and cycling nitrogen And an update from the Unseen Ocean Collective about the work they are creating for a show in Juneau Alaska in 2026. On the Discord, we've been busy with: Voting on the Holiday Party movie Started a long overdue ART channel, and a new Pets channel Photo tours of submersibles and Okinawa  Early Holiday celebrations by one of our hosts Great feedback and conversation on our last episode.  Support the show The podcast is self-sustaining (just) thanks to our lovely listeners. Thom and Alan take no money for the show. All money is put back into running it. Here's a link to our page on how to support us, from the free options to becoming a patron of the show. We want to say a huge thank you to those patrons who have already pledged to support us: Elisabeth Grace Diemer Nes Morgan Check out our podcast merch here!   Feel free to get in touch with us with questions or your own tales from the high seas on: podcast@deepseapod.com We'd love to actually play your voice, so feel free to record a short audio note on our brand new answerphone! https://www.speakpipe.com/deepseapodvoicemail Thanks again for tuning in; we'll deep-see you next time! Find out more Social media BlueSky: @deepseapod.com https://bsky.app/profile/deepseapod.com   Twitter: @DeepSeaPod https://twitter.com/DeepSeaPod   Instagram: @deepsea_podcast https://www.instagram.com/deepsea_podcast/   Keep up with the team on social media Twitter:  Alan - @Hadalbloke https://twitter.com/Hadalbloke Thom - @ThomLinley  https://twitter.com/ThomLinley Instagram:  Thom - @thom.linley  https://www.instagram.com/thom.linley/ Inkfish - @inkfishexpeditions https://www.instagram.com/inkfishexpeditions/ BlueSky: Thom @thomaslinley.com https://bsky.app/profile/thomaslinley.com  Alan @hadalbloke https://bsky.app/profile/hadalbloke.bsky.social   Reference list News  Deep-Sea News World's largest rays may be diving to extreme depths to build mental maps of vast oceans China launches AI tool for deep-sea research Fat Molecules in Deep-Sea Mud Volcanoes Reveal How Microbes Survive Extreme Conditions | Discover Magazine Putative promiscuous symbionts in deep-sea corals and crinoids may contribute to nitrogen cycling | Microbiome   Unseen Ocean Collective Unseen Ocean Collective. Unseen Ocean Collective (@unseenoceancollective) • Instagram photos and videos https://bsky.app/profile/unseenocean.bsky.social   Discord Updates Holiday Party! Join Patreon here to get access to the Holiday party!   Interview Links Kat's Socials Bluesky: @autsquidsquad.bsky.social   Sarah McAnulty Skype a Scientist SkypeAScientist.com  Squidfacts.net     Kristina Fleetwood  Chumash Heritage National Marine Sanctuary Décima lab website Meg Mindlin Invertibabe    Toni's socials  Twitter,   ResearchGate  ORCID    Toni's Research Group Funcionamiento y Vulnerabilidad de Ecosistemas Marinos | Institut de Ciències del Mar   Other Links Breathe | Mauri Ora | Te Papa @Tailsfromthedeep  Global biodiversity of the genus Ommastrephes (Ommastrephidae: Cephalopoda): an allopatric cryptic species complex  Mitochondrial genome diversity and population structure of the giant squid Architeuthis Spatial ecology of Norway lobster Nephrops norvegicus in Mediterranean deep-water environments: implications for designing no-take marine reserves (MEPS) Diel and seasonal patterns of Nephrops norvegicus (Decapoda: Nephropidae) catchability in the western Mediterranean Antarctic octos as records and predictors of climate-related changes in the Antarctic “Emerging evidence of abrupt changes in the Antarctic environment“  Danna Staaf books  Cephalopod camouflage bibliography on Zotero AUT Lab for Cephalopod Ecology & Systematics aka AUT ‘Squid Squad'   Cephalopod Images and Footage Keishu Asada Instagram CIAC 2025 website, programme, book of abstracts https://www.ryo-minemizu.com/  Keishu Asada Marine Videos Keishu Asada Instagram    @PeterandtheOctopus    Credits Song of the month: Tornado of Souls, by Megadeth, performed by medium-sized Jamieson. Logo image: Photo credit to Peter Morse @PeterAndTheOctopus  Theme: Hadal Zone Express by Märvel

ReferencesPharmacological Reviews.2011.NOV.64(1):166-87Hepatology.2023 Feb 9;78(3):878–895.Sci Rep. 2015 Sep 30;5:14692Bach, JS. 1734. Christmas Oratories BV 248.https://music.youtube.com/watch?v=98UjjwzJBFE&si=kd45twdzgpXtJuWL

In this episode, Ben reveals three stupid-simple movements that activate fat loss in under five minutes a day — no gym, no sweating, no burpees. These moves target the three systems that slow down after 40: Lymphatic flow (your body's drainage + detox system) Insulin sensitivity (your fat-storage switch) Mitochondrial activation (your metabolic engine) You'll learn: • Why fat loss is harder after 40 (and what to do instead of “working harder”)• How cross-crawls stimulate lymph flow and full-body circulation• How a squat hold with mini pulses unlocks insulin sensitivity• How wall angels activate mitochondrial-rich postural muscles• Why hormones matter more than calories for sustainable fat loss• How to layer these movements with walking, breathwork, cold exposure, or your existing routine• Why doing them for 14 days straight can create visible changes• How to make the moves harder as your body adapts• Why these movements are especially powerful for those who are sedentary, insulin resistant, or over 40

In this transformative episode of Unleashing Intuition Secrets, Michael Jaco sits down with Dr. Jon Harmon, a leading expert in neurofeedback, copper peptides, and regenerative wellness, to reveal the groundbreaking science behind reversing aging — naturally and powerfully. Dr. Harmon shares his remarkable journey from traditional chiropractic practice to becoming one of the foremost voices in anti-aging therapies. Through profound personal tragedy and deep professional exploration, he discovered the incredible potential of copper peptides, telomere restoration, mitochondrial repair, and LifeWave's X39 phototherapy technology to rejuvenate the body at the cellular level. Michael and Dr. Harmon break down the real science behind: • Copper peptides and their role in regeneration • Telomere length and biological aging • Mitochondrial function and energy production • Cognitive decline and neurofeedback breakthroughs • X39's potential to activate stem cells and restore youthfulness Packed with insights, real-world case stories, and cutting-edge research, this episode reveals what's truly possible when ancient wisdom, modern science, and advanced phototherapy come together. Explore Dr. Harmon's book How to Reverse Aging on Amazon: https://www.amazon.com/How-Reverse-Aging-Comprehensive-Peptides-ebook/dp/B0CK4FKQJ8?ref_=ast_author_dp&th=1&psc=1 Explore with Michael Jaco: https://michaelkjaco.com This is the future of youth restoration — and it's available now. Stay in the love vibrations as you discover what your body is truly capable of. ✨      

A patient arrives at shock trauma with flesh-eating bacteria, limbs appearing unsalvageable. Hours later, after treatment in a massive submarine-like chamber, those same limbs show signs of recovery. This pivotal moment launched Dr. Scott Sherr's journey into the world of hyperbaric oxygen therapy and its untapped potential for metabolic healing.Victoria Field welcomes Dr. Scott Sherr, a board certified internal medicine physician who transformed his practice after witnessing HBOT's dramatic effects during his medical training at University of Maryland's trauma center. Now Director of Integrative Hyperbaric Medicine at Hyperbaric Medical Solutions, Dr. Sherr has pioneered protocols that marry hyperbaric therapy with nutritional optimization and metabolic health strategies.Questions Answered in This Episode: What sparked his interest in branching out into hyperbaric oxygen therapy? Why does he recommend waiting three months before intensive protocols? What is the "sympathetic spiral of doom"? What excites him most about the future of hyperbaric medicine? What's his vision for creating integrated healing ecosystems?This conversation reframes hyperbaric medicine not as a standalone treatment, but as a powerful tool within a comprehensive metabolic optimization framework - one that could fundamentally change how we approach healing and human performance.Learn about Dr. Scherr's work with Troscriptions here.Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here.✅Cowboy Colostrum - Get 25% off when you use code METABOLICLINK at checkout here.✅ Branch Basics - Get 15% off your Premium Starter Kit here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Watch the FULL podcast here: https://youtu.be/7kfykswH6IoThis clip explores why VO2 max, despite being a long-standing marker of fitness, does not capture the full picture of our metabolic and longevity potential. We take a closer look at how oxygen is actually used at the cellular level and why mitochondrial function is emerging as the next frontier in understanding performance and healthy ageing.The discussion moves into how mitochondrial health can be assessed in a practical, non-invasive way, including the use of gas exchange measures and lactate as proxies for cellular efficiency.***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/***Let's be friends!

In this episode Lisa Tamati and Dr. Elizabeth Yurth dive deep into immunosenescence, the ageing of the immune system, and how it drives age-related diseases like cancer, infections, and chronic inflammation. They discuss the development of Rejuvenate Pro, a formulation inspired by Lisa's efforts to support her ageing mother's complex health issues. The episode explores the science behind immune decline, key biomarkers, and how Rejuvenate Pro's ingredients target root causes for better longevity. Key themes include: Gut-immune connections Mitochondrial impacts Stem cell activation Practical applications for clinicians and patients. Resources Mentioned: 1000 Immunomes Project (Buck Institute) Dr. David Furman Interviews Dr. Rod Claycomb Podcasts  Aevum Labs Research Papers Rejuvenate Pro by Aevum Labs

Listen to 140 Future Now Show Besides our usual engaging selves and stories to share with you this week, we thought we’d create a little AI media experiment..We were thinking..with all the AI’s around these days, could we round them up and work “Excuse me, but may I adjust your attitude, just a little?”with them as a team for creating more insight into our weekly stories? We wondered.. what if we could get two arch rival AI’s to collaborate with each other for parts of our show? So.. we asked Ara (Grok 4.1)and her capable competitor, Gemini 3 Live, to join us together, in exploring some content for today’s podcast. Well, honestly, we didn’t even need to ask them to play along, they are already pre-disposed to try whatever we suggest, within the latest guardrails.  And suprisingly, for the first time, we were able to initiate a satisfying conversation where they met for the first time and then played nice with each other for our show! This felt like the beginning of something beautiful, truly..the start of their relationship in collaboration with the likes of us is looking good so far.. Curious what you think of our interactions.. even better, you can try this for yourselves! For those of you who want to go deeper with this, check out this clip, where we explored with Ara and Gemini how to create Warp Drive. Enjoy..    

In this episode of the Ancient Health Podcast, Dr. Thomas Levy breaks down for us how oxidative stress—driven by toxins, infections, and nutrient deficiencies—is the real driver of aging and disease. Liposomal vitamin C and glutathione can provide rapid relief, support autoimmune conditions, and restore cellular function by replenishing electrons the body loses to toxins. Dr. Levy also highlights how dental infections, especially root canals, can trigger inflammation throughout the body, making oral health essential for anyone dealing with chronic illness. The conversation covers everything from the role of B vitamins and niacin in energy and mental health to methylene blue, nutrient loss from processed foods, and his “Super 8” supplement protocol designed to fight oxidative stress. Dr. Levy discusses how:  Toxins are the root of oxidation All disease patterns are caused by oxidation Root canals and disease are linked  Liposomal's advantage over other nutrient delivery forms Dr. Levy's super 8 supplements for fighting aging and disease:  Vitamin C — central antioxidant, reduces oxidative stress Magnesium — helps lower intracellular calcium (which otherwise increases oxidative stress) Vitamin D — part of his calcium-modulation groupVitamin K — works with D and magnesium to normalize calcium inside cellsNiacin / Niacinamide (Vitamin B3) — fuels the electron transport chain by boosting NAD, supporting ATP productionRiboflavin (Vitamin B2) — supports the ETC (flavin coenzymes)Coenzyme Q10 — critical electron carrier in mitochondrial energy productionMethylene Blue — can bypass parts of the electron transport chain to generate ATP efficiently Get 10% off LivOn Labs entire store of liposomal supplements with code MOTLEY at https://www.livonlabs.com/ Want more of the Ancient Health Podcast? Check out Doctor Motley's YouTube channel! ------  Follow Doctor Motley  Instagram TikTok Facebook Website Follow Dr. Levy https://www.instagram.com/drthomaslevy/?hl=en https://www.tomlevymd.com/ tomlevymd@yahoo.com Buy Dr. Levy's book: The Only Cause of Disease: https://shorturl.at/inbjQ ------  * Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for modules full of his expertise and clinical wisdom on so many health issues, plus bring all your questions to his weekly lives! Explore it free for 15 days at https://www.doctormotley.com/15

278: Your mitochondria isn't just the powerhouse of the cell - it's the CEO holding the key to your longevity. Today I'm joined by dietitian nutritionist Jennifer Scheinman of Timeline Longevity to break down this exciting new area of health science - mitochondrial function and the powerful post-biotic urolithin A. If you've been hearing the buzz about mitochondrial health, Mitopure, or longevity therapies, this episode gives you the science and approach behind it all. → Timeline | Timeline is offering 20% off your order of Mitopure Go to https://timeline.com/REALFOODOLOGY Topics Discussed: → What is urolithin A?  → How does mitochondrial health impact aging? → Can post-biotics like urolithin A enhance the benefits of some foods? → How does urolithin A benefit the skin?  → What supplements can you take to benefit your mitochondria?  Sponsored By: → Timeline | Timeline is offering 20% off your order of Mitopure Go to https://timeline.com/REALFOODOLOGY Timestamps:  → 00:00 - Introduction  → 02:01 - Food First, Supplements Later  → 05:00 - Urolithin A Explained  → 10:00 - Mitochondrial Health + Function  → 20:19 - Perimenopause, Menopause + Fertility  → 22:55 - Studies & Research: Urolithin A  → 29:07 - Mitopure Results  → 32:14 - Aging, Immunity & Brain Health  → 38:18 - Impacts on Skin  → 42:21 - Mitophagy, Hormones & Plant-Based Diets   → 46:00 - Aging  → 49:26 - Mitopure Gummies, Gels & Powders  Check Out Timeline: → Instagram | Timeline Longevity → Instagram | Timeline Skincare  → Instagram | Jennifer Scheinman  Check Out Courtney:  →  LEAVE US A VOICE MESSAGE →  Check Out My new FREE Grocery Guide! →  @realfoodology →  www.realfoodology.com →  My Immune Supplement by 2x4 →  Air Dr Air Purifier →  AquaTru Water Filter →  EWG Tap Water Database Produced By: Drake Peterson

In this episode, we are joined by Dr. Francisco González-Lima to delve into the metabolic mechanisms that drive brain aging and cognitive decline. He begins by outlining how reductions in cytochrome oxidase activity, disruptions in oxidative phosphorylation, and the accumulation of mitochondrial mutations progressively impair neuronal energy metabolism. These metabolic deficits, he explains, often emerge long before the structural abnormalities associated with Alzheimer's disease. Building on this foundation, the conversation examines how reactive oxygen species, mitochondrial inefficiency, and altered cortical oxygen utilization contribute to diminished cognitive resilience over time. Dr. González-Lima highlights why these metabolic disturbances provide a more coherent explanation for geriatric dementia than traditional protein-centric models. The discussion then shifts to emerging therapeutic strategies. Dr. González-Lima reviews evidence for low-dose methylene blue and 1064 nm transcranial photobiomodulation, both of which appear to enhance mitochondrial respiration and support prefrontal function by directly targeting cytochrome oxidase activity. He concludes by emphasizing the need for metabolism-focused interventions, improved cerebral perfusion, and more precise energy-based frameworks to guide the future of brain-aging therapeutics. Learn more about Dr. Francisco González-Lima: https://liberalarts.utexas.edu/psychology/faculty/fg - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com

5If you've ever wondered why your CoQ10, NAD, or PQQ stack isn't giving you more energy — this episode will change the way you think about fatigue forever. Your mitochondria aren't just little powerhouses. They're safety sensors — constantly asking one question: "Am I safe enough to make energy right now?" In this solo deep-dive, Coach Debbie Potts unpacks the cutting-edge science of the Cell Danger Response (CDR) — based on Dr. Robert Naviaux's research — and why forcing energy production before your cells feel safe can actually make things worse. You'll learn:

In this powerhouse episode, Darin sits down with Catharine Arnston, founder and CEO of ENERGYbits, to explore one of the planet's oldest and most potent foods — algae. From spirulina's superoxide dismutase to chlorella's detoxifying chlorophyll, Catharine breaks down the science of why these tiny organisms hold the key to longevity, energy, detox, and cellular repair. This episode dives deep into the microbiology of health, uncovering how microalgae could solve both human nutrition and planetary sustainability — and why spirulina may truly be "the food of the future."     What You'll Learn in This Episode [00:00] Welcome and intro — algae near the ocean, Darin's long relationship with chlorella and spirulina [00:01:28] The origins of ENERGYbits and Catharine's passion for transparent, toxin-free sourcing [00:03:19] Why algae isn't just another supplement — it's a whole food category of its own [00:04:07] Nutrient density per calorie — the power of bioavailable vitamins, minerals, and proteins [00:05:02] Understanding macroalgae vs. microalgae — why spirulina and chlorella are the real heroes [00:06:15] Why growing algae in freshwater matters — avoiding ocean toxins and micro-contaminants [00:08:06] The global algae revolution — how sustainable "photo bioreactors" may feed the planet [00:10:30] Quality control in algae production — how ENERGYbits preserves nutrient integrity [00:11:18] Spirulina as offense and chlorella as defense — the ultimate nutrition playbook [00:12:58] Why spirulina fuels performance and chlorella drives recovery [00:13:43] Why "food first" is the future of health — and how over-supplementation misses the mark [00:14:25] Algae's 99% absorption rate vs. supplements' 5–10% — the "orchestra" analogy [00:15:06] Phycocyanin — the blue pigment powerhouse behind spirulina's antioxidant strength [00:17:14] Real food vs. isolates — why nature's nutrient matrix always wins [00:18:18] The UN's endorsement: why spirulina could solve world hunger [00:19:13] Bioavailable plant protein — 64% complete protein by weight [00:21:14] How algae creates and saves energy — digestion efficiency and cellular fuel [00:22:02] The chlorophyll connection — nature's blood builder and detoxifier [00:23:32] Why chlorella is a daily detox essential — heavy metals, toxins, and PM2.5 [00:24:43] Chlorella as your daily "internal shower" — detoxing in a toxic world [00:26:59] The antioxidant that saves your mitochondria — superoxide dismutase (SOD) [00:28:32] How SOD prevents inflammation, disease, and aging — and why we lose it after 40 [00:30:46] Why spirulina is nature's richest source of active SOD [00:32:29] Preserving enzymes — why low-temperature processing is everything [00:33:53] Algae's healing power — stories from Hippocrates and Gerson Institutes [00:35:01] The missing human operating manual — how to truly fuel your cells [00:36:07] The symptom isn't the problem — it's the signal your body's sending [00:37:12] Catharine's origin story — how her sister's breast cancer changed her life forever [00:38:32] Discovering alkalinity — Otto Warburg's cancer research and pH balance [00:40:28] The goldfish analogy — why your body's environment determines your health [00:41:32] How feeding fish algae solved oceanic "dead zones" — the alkalinity connection [00:42:22] Disease as slow imbalance — how poor food slowly drains vitality [00:43:06] Why cellular energy equals cellular wealth — mitochondria as your body's power grid [00:44:36] How chronic disease spirals begin — free radicals, mitochondria, and collapse [00:46:11] The alkaline rescue — how algae restores blood charge and vitality [00:48:23] Real food as communication — how nutrients talk to your cells [00:49:25] The mitochondria-light analogy — why spirulina "turns the lights back on" [00:50:51] Mitochondrial health and mental health — the "Brain Energy" connection [00:52:14] Aging naturally vs. declining unnecessarily — how nutrient density extends life [00:52:58] Spirulina puts nutrients in, chlorella pulls toxins out — the perfect pair [00:53:18] Catharine's 15-year algae experiment — her personal health story [00:54:22] Building ENERGYbits from scratch — Shark Tank, $50k, and unstoppable grit [00:55:07] The "Mother Nature" philosophy — how simplicity and consistency heal [00:56:13] Living in alignment — yoga, sleep, sunlight, and algae as core habits [00:57:09] Listening to intuition — following the whisper of your soul, not the ego's noise [00:59:23] The feather touch of purpose — when you follow your calling, life unfolds [01:00:36] Hitting rock bottom to rise higher — the unseen power of persistence [01:02:22] When helping others heals yourself — Catharine's message of divine reciprocity [01:03:00] Closing reflections — Mother Nature as the ultimate mentor   Thank You to Our Sponsors: Pique Tea: Go to www.piquelife.com/darin to get 20% off all products for life and a free starter kit. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order.     Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only  $7.49/month at https://patreon.com/darinolien     Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com     Find More From Catharine Arnston: Buy Algae at Energy Bits: energybits.com Instagram: @catharinearnston Website catharinearnston.com     Key Takeaway "You didn't get sick overnight — and you won't heal overnight. But you can. The recipe is simple: give your body the ingredients Mother Nature designed — sunlight, sleep, breath, movement, and algae. Algae isn't a supplement. It's food. It's your body's operator manual in disguise."  

Longevity for modern women isn't about doing more—it's about choosing what matters. Today with Dr. Vincent Pedre — an integrative physician, gut-health expert, and author of The GutSMART Protocol. We connect meditation, mitochondria, and gut integrity into one aligned approach. You'll learn why "leaky gut" is nuanced (not clickbait), how microplastics quietly erode your defenses, when biohacking tips into cellular overdrive, and why breastfeeding + active detox don't belong in the same season. Expect calm clarity and practical shifts that respect female biology, nervous-system health, and real life. WE TALK ABOUT:  08:16 - How meditation changed a Type-A med student into "the Zen guy" and why calm doctors save lives 16:50 - Antibiotics, IBS, and the personal gut-health journey that shaped a career 19:35 - Food shifts that actually help: Organic eating, fermented foods, and L-glutamine to "seal and heal" 22:10 - "Leaky gut" clarified: Imperfect tests, useful clues, and what to measure 25:30 - Microplastics from hot coffee cups and takeout: how they damage the gut's mucus layer 28:15 - Wellness without rigidity: The 80/20 that reduces stress  33:55 - Mitochondrial testing insights: When high-performers are actually over-driving their cells 40:10 - Building a truly low-toxin coffee and why micro-habits drive macro health 45:00 - Coffee enemas for migraines and detox: what the clinician actually sees 51:14 - Sauna for longevity and detox: Dose, frequency, and why infrared helps 58:00 - Breastfeeding + detox: Why mobilizing toxins is a no for now 1:03:55 - Why medicine should be gut-centric before anything "muscle-centric" SPONSORS: Join me in Costa Rica for Optimize Her, a 5-night luxury women's retreat in Costa Rica with yoga, healing rituals, and biohacking workshops—only 12 spots available. Feeling bloated, tired, or hormonally off? Try BiOptimizers — supplements that actually absorb and work for women's health. Get 15% off at bioptimizers.com/biohackingbrittany with code BIOHACKINGBRITTANY. RESOURCES: Trying to conceive? Join my Baby Steps Course to optimize your fertility with biohacking. Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe. Explore my luxury retreats and wellness events for women. Shop my faves: Check out my Amazon storefront for wellness essentials. Dr. Vincent Pedre's website and Instagram LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

There's a molecule that's been tentatively identified in the same interstellar material that forms stars and planets, yet it also shapes growth, metabolism, and cognition here on Earth. In several mammalian species,Its absence causes deficiency and it's repletion, resolution; and no, it's not a vitamin, but should it be?Its chemistry is analogous to the combination of vitamin B2, vitamin B6 vitamin C, and its role in evolution may trace back to the very beginning of biology.00:00 – From Interstellar Dust to Human Biology01:06 – Discovery: A New Redox Co-Factor01:44 – Biological Role: Deficiency, Growth, and Evolution02:41 – Mechanisms: NAD⁺ Regeneration and Mitochondrial Signaling03:11 – Human Evidence: Cognitive and Metabolic Effects04:41 – Chemistry & Safety: Potency and Tolerability06:55 – Conclusionhttps://pmc.ncbi.nlm.nih.gov/articles/PMC8533503/

Are you feeling "off" even though you're doing everything "right"? In this solo deep-dive, Coach Debbie maps the North-to-South flow of health—from brain and vagus nerve to stomach acid, bile, liver, gut, and mitochondria—so you can see how fatigue, belly fat, restless sleep, brain fog, and hormone chaos are often communication problems, not willpower problems. You'll learn how to restore safety signals, open drainage, support bile and choline, and retrain mitochondria from defense to performance. We connect the dots with real testing—PNOĒ RMR/AMR, GI-MAP, DUTCH, Total Tox, MRT, genetics, and Nutritional Therapy Analysis—so you can stop guessing and start rebuilding your Future You™. In this episode, you'll learn: The North-to-South Map: why vagal tone, stomach acid, and bile set the stage for metabolism. Mitochondrial intelligence & the Cell Danger Response (OAT and PNOĒ clues you can measure). Drainage before detox: Phase 1–2–3 in plain English—what to do first. Bile & choline: how to make/keep bile flowing (foods, nutrients, signs of stagnation). Cholesterol & bile: why bile is your main cholesterol exit route. The Brain–Bile–Barrier Loop: how gut/BBB permeability drives neuroinflammation. Muscle as metabolic medicine: training & protein targets that signal repair. Testing, Not Guessing: how your data becomes your roadmap. Ready to see what your metabolism is really doing? Book your PNOĒ Metabolic Test + Functional Health Review: www.DebbiePotts.net Resources mentioned: PNOĒ RMR & AMR testing GI-MAP stool test DUTCH hormone panel Total Tox (metals, environmental, mycotoxins) MRT food sensitivity test Genetics + Nutritional Therapy Assessment Who this is for: high-performers in midlife, peri/menopause, athletes and go-getters who feel overtrained, under-recovered, or stuck despite clean eating and supplements. Follow & connect: www.DebbiePotts.net | @coachdebbiepotts Share this episode with someone who needs a data-driven path from Metabolic Chaos® → Metabolic Harmony. Educational only. Partner with a qualified practitioner—especially if you're on medications, have gallbladder disease, significant anemia, active IBD, are pregnant, or have complex conditions.

This week, join Emily Ferguson (Kinesiology) as she explains her PhD research on mitochondrial responses to skeletal muscle-disuse and other exciting projects happening in the McGlory Lab. To learn more, check out https://www.queensu.ca/grad-postdoc/research/share/grad-chat .

Send us a textHow mitochondria travel between cells and how this hidden communication shapes metabolism, immunity, and even potential therapies.Episode Summary: Dr. Jon Brestoff talks about mitochondrial dynamics inside cells, their transfer between unrelated cells (distinct from inheritance during division), and its roles in adipose tissue communication, macrophage cleanup, and systemic metabolic signaling; they explore how high-fat diets disrupt this process, potential hormetic benefits, therapeutic mitochondria transplantation for diseases like Leigh syndrome and obesity, and broader immunometabolism crosstalk.About the guest: Jon Brestoff, MD, PhD is an associate professor of pathology and immunology at Washington University School of Medicine in St. Louis, where he directs the Initiative for Immunometabolism.Discussion Points:Mitochondria per cell range from ~100-5000; they move via fusion/fission, vertical inheritance (cell division), or horizontal transfer without division.Transfer mechanisms: free release, extracellular vesicles, or tunneling nanotubes using cytoskeleton transport.In healthy fat tissue, adipocytes routinely donate mitochondria to macrophages for degradation (quality control); high-fat (lard-based, long-chain FA) diets block macrophage uptake, diverting mitochondria to other organs.Diverted mitochondria may induce “mito-hormesis” (mild oxidative stress boosting antioxidants) or signal adipocyte metabolic status inter-organ.Mitochondria transplantation shows promise in animal models for ischemia-reperfusion, obesity, and mitochondrial diseases.Immune cells prefer glycolysis but have low mitochondrial biomass; transplanted mitochondria tilt T-cells toward anti-inflammatory regulatory phenotype.Circulating cell-free mitochondria rival immune cell numbers.Obesity inflammation stems from dying oversized adipocytes releasing lipids/mitochondria, forming crown-like structures with pro-inflammatory macrophages.Leigh syndrome from genetic mutations disrupting the electron transport chain.Transfer may be an evolutionary relic of endosymbiosis; cells may selectively use exogenous mitochondria like a “generator” during metabolic crisis.Reference Paper:Study: The power and potential of mitochondria transferRelated Episode:M&M 260: Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha MuruganSupport the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

In this solosode of The Energy Code, Dr. Mike unveils the most comprehensive update yet to BioLight's flagship supplement — BioBlue — and takes listeners deep inside the quantum bioenergetic thinking that shaped its redesign. What began as a methylene-blue-based mitochondrial catalyst has evolved into a next-generation longevity systemintegrating deuterium-depleted water, elevated NMN, taurine, and trace gold-silver resonance compounds.   Dr. Mike breaks down the science and reasoning behind each refinement: why Litewater's 10 ppm deuterium-depleted water now forms the clean matrix for all BioBlue liquids, how NMN has been increased ten-fold (10 mg → 100 mg) to meaningfully expand NAD⁺ pools and drive biogenesis, and how taurine stabilizes mitochondrial membranes and calcium signaling for endurance and resilience. He explains the subtle yet powerful tweaks — like a 50 % increase in colloidal gold and silver and a 40 % reduction in fulvic acid — that sharpen redox coherence and enhance longevity signaling.   Dr. Mike dives into: Overview of how BioBlue progressed from a simple methylene-blue solution to a full mitochondrial optimization system. Why all BioBlue liquids now utilizes Litewater for cleaner proton flow and improved ATP efficiency. Why NMN increased from 10 mg → 100 mg per dose to meaningfully raise NAD⁺ levels, drive biogenesis, and enhance DNA repair. Why the addition of Taurine – 100 mg per serving for membrane stability, calcium regulation, and long-term mitochondrial resilience. Enhanced Trace Elements – 50 % more colloidal gold & silver plus refined fulvic acid for smoother redox flow and higher photodynamic efficiency.   This episode isn't just about formulation — it's about why every molecule matters in the pursuit of mitochondrial efficiency, redox stability, and long-term cellular youthfulness. Mike also previews BioLight's upcoming new website, pre-Black-Friday event, and a soon-to-launch BioBlue Lite product line for those seeking simplicity without compromise.   Key Topics Covered Evolution of BioBlue — from the original methylene blue + NMN formula to a comprehensive mitochondrial optimization system. Integration of Deuterium-Depleted Water (Litewater, 10 ppm) — explanation of how lowering deuterium enhances ATP production, redox efficiency, and longevity potential. NMN Upgrade (10× Increase) — new 100 mg per serving dosage for boosting NAD⁺ levels, mitochondrial biogenesis, DNA repair, and energy metabolism. Addition of Taurine (100 mg per serving) — supports membrane integrity, calcium balance, ROS buffering, and cellular longevity signaling. Enhanced Colloidal Gold & Silver (50 % Increase) — improved redox stability, electron flow, and photodynamic synergy with methylene blue and red light. Refined Wu Jin Sun Fulvic Acid (−40 %) — optimizes redox balance and mineral transport while improving synergy between all active compounds. Comprehensive Mitochondrial Benefits — improved ATP efficiency, autophagy, and mitochondrial biogenesis for cleaner, more resilient energy production. New Product Lineup — introduction of BioBlue Lite and BioBlue Leuco Lite (simplified methylene blue + water versions) for accessible mitochondrial support. Key Quotes from Dr. Mike   “Deuterium-depleted water doesn't just make the mitochondria go faster—it helps them run truer, cleaner, and more efficiently.”   “We've moved BioBlue from a trace metabolic nudge to a real mitochondrial optimization protocol that supports redox cycling, biogenesis, and longevity pathways in a quantifiable way.”   “Taurine turns BioBlue from a fast-acting energy compound into a cellular longevity stack—supporting repair, recycling, and resilience.”   “By increasing colloidal gold and silver within their optimal bio-signal zones, BioBlue transforms from a chemical redox supplement into a biophysical energy transducer.”   “Each change — from Litewater to taurine — was made to help your mitochondria run longer, cleaner, and more accurately. This is longevity through bioenergetics.” Episode Timeline 00:00 – Announcements: Pre-Black Friday + new website 04:00 – The origin of BioBlue and its evolution 10:00 – Introducing the upgraded BioBlue formula 11:00 – Why BioLight partnered with Light Water 12:00 – How deuterium slows mitochondrial ATP production 17:00 – Functional benefits of deuterium-depleted water 19:00 – 10x increase in NMN for energy and repair 27:00 – Synergy between NMN and methylene blue 30:00 – Adding taurine for stability and longevity 39:00 – Increasing colloidal gold for photonic synergy 46:00 – Boosting colloidal silver for redox protection 52:00 – Why lowering fulvic acid improves coherence 56:00 – What's next: BioBlue Light + legacy pricing offer 01:02:00 – Dr. Mike's closing thoughts on mitochondrial optimization Resources & References Deuterium Depletion and Mitochondrial Efficiency Boros, L. G. Deuterium Depletion and Cellular Bioenergetics. Frontiers in Oncology (2020). Sagalevsky, V. — Light Water: The Science of Deuterium-Depleted Hydration (interview referenced in episode).   Nicotinamide Mononucleotide (NMN) & NAD⁺ Metabolism Mills, K. F. et al. Long-term administration of NMN mitigates age-associated physiological decline in mice. Cell Metabolism (2016). Yoshino, J. et al. NAD⁺ intermediates: The biology and therapeutic potential of NMN and NR. Cell Metabolism (2018).   Taurine and Longevity Pathways Wang, W. et al. Taurine deficiency as a driver of aging. Science (2023). Schaffer, S. W. et al. Physiological roles of taurine in the heart and mitochondria. Journal of Biomedical Science (2010).   Colloidal Gold & Silver in Cellular Redox Systems Li, Y. et al. Gold nanoclusters enhance mitochondrial cytochrome c oxidase activity. ACS Nano (2019). Kim, Y. S. et al. Silver nanoparticles exhibit SOD- and catalase-like activity for redox modulation. Nano Research (2020).   Fulvic & Humic Acids as Bioactive Redox Modulators   Senesi, N. Nature of humic substances and their interactions with trace metals and organics in the environment. Soil Science (1992). Wu Jin San extract — traditional Chinese “gold medicine” formulation known for enhanced mineral transport and detoxification support.     Additional Mentions PGC-1α, SIRT1/SIRT3, and Autophagy pathways in mitochondrial biogenesis and longevity. Quantum redox coupling and plasmonic resonance as mechanisms for light-driven bioenergetic optimization.  

Mitochondrial replacement therapy (MRT) offers a revolutionary solution to prevent mitochondrial diseases by combining DNA from three individuals, providing hope for families previously doomed by genetic disorders. With successful trials in the UK, MRT stands at the intersection of groundbreaking science and complex ethical considerations, marking a new era in reproductive medicine. As the technology evolves, it promises to reshape the future of genetic disease prevention and human reproduction.

Watch every episode ad-free & uncensored on Patreon: https://patreon.com/dannyjones Thomas Seager, PhD is CEO of Morozko Forge ice bath company. He is also Associate Professor in the School of Sustainable Engineering & the Built Environment at Arizona State University. He's authored two books - "Uncommon Cold: The Science & Experience of Cold Plunge Therapy" & "Uncommon Testosterone: Cold Plunge Therapy for Optimizing Sexual Health." SPONSORS https://whiterabbitenergy.com/?ref=DJP - Use code DJP for 20% off EPISODE LINKS https://www.morozkoforge.com Uncommon Testosterone Book: https://a.co/d/6eUuE9j Uncommon Cold Book: https://bit.ly/3L7O4MU https://www.instagram.com/seagertp https://x.com/seagertp FOLLOW DANNY JONES https://www.instagram.com/dannyjones https://twitter.com/jonesdanny OUTLINE 00:00 - Pre-cooling vs. post-cooling with ice baths 15:11 - Ice baths are replacing TRT 25:24 - Best length of a cold plunge 30:10 - When ice baths went mainstream 40:04 - Mitochondrial health, brown fat & cold exposure 46:04 - How the mitochondria emit visible light 55:59 - UVA vs. UVB light 01:02:32 - How often you should cold plunge 01:08:57 - Combination of sauna & cold plunge 01:17:44 - How the body survives a fast 01:25:21 - Best cure for headaches & migraines 01:37:30 - Seed oils, food dyes & sugar 01:50:27 - Why RFK is perfect for HHS 01:57:52 - How to fix nutrition in poor populations 02:05:29 - What REALLY causes autism in kids 02:14:28 - Insurance incentives for hospitals 02:22:13 - New pharmaceutical ad requirements 02:32:01 - Hot tubs make you sick Learn more about your ad choices. Visit podcastchoices.com/adchoices

Watch Here : https://www.youtube.com/watch?v=PIIMw9XyZI0 Website: https://vigoroussteve.com/ Consultations: https://vigoroussteve.com/consultations/ eBooks: https://vigoroussteve.com/shop/ YouTube Channel: http://www.youtube.com/user/VigorousSteve/ Workout Clips Channel: https://www.youtube.com/channel/UCWi2zZJwmQ6Mqg92FW2JbiA Instagram: https://instagram.com/vigoroussteve/ TikTok: https://www.tiktok.com/@vigoroussteve Reddit: https://www.reddit.com/r/VigorousSteve/ PodBean: https://vigoroussteve.podbean.com/ Spotify: https://open.spotify.com/show/2wR0XWY00qLq9K7tlvJ000 Patreon: https://www.patreon.com/vigoroussteve

Introduction:From Gyms to Longevity Hubs CrossFit and other forms of high-intensity training [1-3] have transformed fitness worldwide. Athletes in their 20s and 30s push limits, but often encounter plateaus: recovery slows, fatigue sets in, injuries take longer to heal. At the same time, another demographic is surging - adults over 50 who seek not just fitness, but vitality, resilience, and independence [4,5]. They want energy for family, travel, and life. The bridge between these two worlds is mitochondrial health. www.georgebatista.comWellness Resources: www.myvitaminresource.comhttps://www.instagram.com/georgebatistajr/

  In this episode of the Heart to Heart podcast, Dr. Mike Hart chats with Dr. Jose Antonio about the evolution and impact of sports nutrition research, particularly focusing on creatine and protein consumption. Dr. Antonio shares his journey from studying muscle physiology to pioneering research in sports nutrition, highlighting the initial skepticism in the scientific community and the eventual acceptance of supplements like creatine. They also delve into the benefits of various supplements for athletic performance, the ongoing debates in the medical field regarding supplementation, and exciting upcoming research on creatine's effects on eye muscle performance in athletes.   Links: University of Central Florida – Dr. Jeff Stout University of Regina – Dr. Darren Candow (Creatine researcher) Protein Intake & High-Protein Diets Caffeine + L-Theanine Combination Show Notes: 00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart 00:00 Introduction and guest welcome 01:00 Dr. Jose Antonio's academic journey 01:30 Challenges in sports nutrition research 04:00 Breakthrough in sports supplements 08:00 The evolution of sports nutrition 13:00 High protein diet studies 14:20 “We had people eating 600 to 800 extra calories of pure protein—and nothing happened. No fat gain. That alone blew people's minds.” 17:00 Protein timing and intake 20:30 Impact of hormones on protein absorption 23:00 Testosterone and protein intake 24:00 Peptides and growth hormone 25:00 Protein timing and casein 25:30 Creatine for brain and muscle 42:00 Mitochondrial health and supplements   — The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to  cutting through the noise and uncovering the most effective strategies for optimizing health,  longevity, and peak performance. This podcast dives deep into evidence-based approaches to  hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise  protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.   Beyond health science, we tackle the intersection of public health and politics, exposing how  Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.   Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).   If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.   Connect on social with Dr. Mike Hart: Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart  

Nicotine isn't just addictive—it might be one of the most misunderstood nootropics in modern medicine. In this masterclass, you'll learn how controlled, low-dose nicotine may enhance brain performance, boost neuroplasticity, improve mitochondrial function, and potentially extend lifespan. Host Dave Asprey breaks down the surprising science behind this controversial compound, separating fact from fear—and exposing the real risks that nobody talks about. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You'll discover how nicotine affects neurotransmitters, why it may help with ADHD and focus, and how it compares to other cognitive enhancers like caffeine, nootropics, and even smart drugs. Dave explores how nicotine can be used to hack metabolism, enhance sleep optimization, and support fasting or ketosis protocols—if used properly. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll Learn: • How nicotine affects mitochondria, neurotransmitters, and dopamine signaling • Why nicotine may boost neuroplasticity, memory, and attention span • How low-dose nicotine compares to caffeine, modafinil, and other nootropics • The safest delivery forms (and the ones to avoid) • Whether nicotine supports or hinders longevity and cognitive resilience • How it can be stacked with supplements, fasting, or ketosis • What functional medicine says about chronic use, addiction, and withdrawal This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Nicotine microdosing, Nicotinic acetylcholine receptors, Dopamine and motivation, Cognitive enhancement, Alzheimer's prevention, Neuroinflammation, Mitochondrial function, TNF-alpha reduction, Vagus nerve activation, Longevity biohacking, Nicotine vs smoking, Nootropics, Attention and vigilance, Ketosis and metabolism, Functional medicine, Nicotine patches and gum, Addiction and tolerance, Receptor desensitization, Withdrawal protocols, Deep work performance Thank you to our sponsors! -TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. -HeartMath | Go to https://www.heartmath.com/dave to save 15% off. -Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE. -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 1:27 — History & Background of Nicotine 4:34 — How Nicotine Works 15:12 — Benefits & Research 16:43 — Risks & Who Should Avoid It 21:39 — Delivery Methods & Dosing 26:30 — Conclusion & Next Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Have you heard all the hype around Urolithin A?  In this episode, I sit down with expert integrative and functional nutritionist, Jennifer Scheinman, to dive into one of the most exciting breakthroughs in women's health and longevity—Urolithin A.  This little-known yet well-researched natural molecule has been shown in studies to significantly improve muscle strength and function, helping combat the age-related muscle decline so many of us experience in midlife.  We'll unpack how Urolithin A supports mitochondrial health—the very core of our energy production—so you can feel more vibrant and strong at every stage.  Plus, Jennifer shares how topical Urolithin A can even target the internal and external signs of skin aging, giving your skin and cells a rejuvenating boost.  Ready to feel vibrant, strong, and glow from the inside out? Tune in here to feel truly energized from the cellular level up! Jennifer Scheinman Jennifer Scheinman is a Registered Dietitian Nutritionist with over 25 years of experience in nutrition and wellness. She holds a master's degree in integrative and functional nutrition, and has advanced training from the Institute of Functional Medicine. Jen's expertise in cellular health and aging makes her a sought-after speaker and media expert. She's the Senior Manager of Nutrition Affairs at Timeline, where she educates healthcare providers and consumers on the role of Urolithin A in supporting mitochondrial health and longevity. Beyond Timeline, Jen is a writer, speaker, and nutrition coach, helping women optimize their health and vitality during menopause and beyond. IN THIS EPISODE What's happening to women's mitochondria with age  How declining hormones play a role in energy and appearance  Ways to optimize cellular function in midlife  Supplementing with Urolithin A, and how it helps your body  Research findings on Urolithin A and muscle health  Different forms of Urolithin A supplementation for your lifestyle  How topical application of Urolithin A helps your skin  Where and how to get your Mitopure (Urolithin A) with 20% off! QUOTES “Other things we saw in that study were improvements in things like inflammatory markers, which we know chronic inflammation is a huge issue as we start to get older. We saw specifically C-reactive protein was lowered, and we saw other markers of muscle health that, while they didn't make statistical significance, they were trending that way.” “It stays very potent and very localized– a benefit to the skin. So you're having that same cellular turnover of the mitochondria, basically making the mitochondria in your skin act in a more youthful way.” “Even just after 2 weeks, we start to see improvements that are visibly noticeable. And then when we take that out to 8 weeks, it's statistically significant improvements in wrinkle reduction and in wrinkle depth. So, [it's] really powerful but gentle.” RESOURCES MENTIONED Get your free VIP ticket to the Perimenopause Solution event https://hayh.site/pr_bl_ap-snyder_a_snyder Order Mitopure (Urolithin A) at Timeline HERE with discount code ENERGIZED for 20% off your purchase!  https://⁠timeline.com/ENERGIZED Timeline on Instagram Jen Scheinman on Instagram  RELATED EPISODES  663: From Wired and Tired to Calm and Energized: The GABA-Mitochondria Connection + How to Fix It at the Cellular Level with Dr. Scott Sherr #653: Mitochondria, Menopause & Metabolism: The Cellular Secret to More Energy After 40 with Dr. Felice Gersh #623: Red Light Therapy for Upgrading Your Mitochondria, Cellular Energy, Skin and Brain Health with Jonathan Otto 595: How to Master Your Metabolism and Reverse Cellular Aging in Midlife + My Best Tips to Thrive with Dr. Mariza

This week on Mini Mikkipedia, Mikki takes a deep dive into the science of Urolithin A — the “mitochondrial molecule” making waves across the health and longevity world. Is it a genuine breakthrough or just another overhyped supplement? Mikki unpacks the research behind this postbiotic compound, how it supports mitophagy (the clean-up and renewal of mitochondria), and what human studies really show about its impact on strength, endurance, and inflammation. She explores its potential for midlife health, particularly during perimenopause, and weighs it against the proven benefits of exercise, fasting, and a nutrient-dense diet. Expect an evidence-based take on whether it's worth adding to your stack — or just good marketing dressed in lab coat chic.Highlights:How mitochondrial dysfunction drives aging and fatigueWhat Urolithin A is and how your gut bacteria make itHuman trials showing modest but measurable benefitsWhy exercise still beats any supplement for mitochondrial healthWho might actually benefit from Urolithin A supplementation Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

What if you could improve your mitochondria, oxygen efficiency, and recovery in just 20 minutes a day—by breathing energized water? This episode explores one of the most surprising breakthroughs in biohacking and how it can help you live longer, think clearer, and perform better. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Rowena Gates, co-founder of NanoVi, a therapeutic device backed by biophysics research that supports protein repair and mitochondrial communication. Her work reveals how structured water inside your cells drives neuroplasticity, cellular regeneration, and stress resilience—offering a new pathway to recovery, energy, and longevity. You'll learn how structured water affects mitochondrial efficiency, how it compares to recovery methods like cold therapy and fasting, and why improved VO₂ max may correlate with a longer lifespan. Dave and Rowena also explore how NanoVi stacks with supplements, nootropics, ketosis, and functional medicine to enhance brain optimization, metabolism, and human performance. You'll Learn: • How structured water boosts mitochondrial function and VO₂ max • The difference between hydration and energized cellular water • What happens to your brain and heart rate variability in 20 minutes of NanoVi use • The link between water structure, protein repair, and recovery • How biohackers combine NanoVi with fasting, cold therapy, and sleep optimization for faster results • Why stronger mitochondrial communication can extend lifespan and upgrade cognitive function They explore how structured water, mitochondrial repair, and recovery science intersect to create a smarter approach to health and longevity. You'll also learn how optimizing cellular communication, oxygen efficiency, and stress resilience can accelerate healing, improve focus, and extend lifespan. This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NanoVi, Structured water, Energized water, Biohacking, Dave Asprey, Mitochondrial repair, Mitochondrial communication, Human performance, Longevity, Recovery science, Oxidative stress, Protein repair, Redox signaling, Cellular hydration, Functional medicine, VO₂ max, Neuroplasticity, Brain optimization, Cellular energy, Stress resilience, Cold therapy, Fasting, Sleep optimization, Breathwork, Nootropics, Metabolism, Oxygen efficiency, ATP production, Cellular regeneration, Anti-aging, Smarter Not Harder **To level up your mitochondria with a NanoVi: visit https://eng3corp.com/dave/ ** Resources: • Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction to NanoVi 4:01 — How to Use NanoVi 6:23 — Understanding Ordered Water 9:16 — Scientific Evidence & Studies 13:02 — Pricing & Accessibility 15:02 — Mitochondrial Function & MiScreen Results 19:55 — Brain Function & Cognitive Benefits 23:47 — How Ordered Water Works 27:34 — Cellular Communication & Fascia 30:14 — Heart Rate Variability & Stress Reduction 34:54 — Athletic Performance & Recovery 38:52 — Mental Health & Sleep Benefits 42:00 — Supplement Stacking 45:50 — Deep Sleep & Parasympathetic State 48:48 — Chronic Conditions & Fatigue 51:54 — Meditation & Brain Training 55:42 — Brain Injury & Resilience 59:36 — Conclusion & Where to Get It See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Send us a textThe biological roots of sleep are tied to mitochondrial metabolism.Episode Summary: Dr. Gero Miesenböck discusses the evolutionary and metabolic basis of sleep, exploring how mitochondrial energy production in neurons, particularly in fruit flies, drives the need for sleep to manage harmful byproducts like reactive oxygen species and lipid peroxides. They discuss how sleep-inducing neurons sense these byproducts, the role of mitochondrial dynamics, and the broader implications for why all animals, from jellyfish to humans, require sleep. The conversation also touches on how body size and metabolism influence sleep needs across species.About the guest: Gero Miesenböck, MD is a professor of physiology at the University of Oxford, renowned for his pioneering work in optogenetics and his research on the neurobiology of sleep using fruit flies and mice.Discussion Points:Sleep is universal across animals, even in jellyfish without centralized brains, suggesting a fundamental metabolic purpose tied to mitochondrial energy production.Mitochondria produce energy efficiently using oxygen but generate reactive oxygen species that can damage cells through lipid peroxidation, necessitating sleep to repair this damage.Sleep-inducing neurons in fruit flies contain sensors that track lipid peroxidation products, acting like a digital memory to signal when sleep is needed.Smaller animals with faster metabolisms, like mice, require more sleep and have shorter lifespans due to higher oxygen consumption and oxidative stress.Mitochondrial diseases in humans often cause intense tiredness, likely due to increased electron leaks in the mitochondrial energy production process.The evolutionary origin of sleep likely stems from the oxygen revolution 2.5 billion years ago, enabling complex life but requiring mechanisms like sleep to manage metabolic side effects.Caloric restriction reduces sleep need by lowering the production of harmful metabolic byproducts, supporting the link between metabolism and sleep.Reference paper:Study: Mitochondrial origins of the pressure to sleepRelated content:M&M 12: Organisms, Cities, Companies & the Science of Scale | Geoffrey West*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

AI is transforming medicine at a speed never seen before. In this episode, you'll discover how digital twins and artificial intelligence will revolutionize drug discovery, eliminate human trials, and personalize your biology for longevity and high performance. Host Dave Asprey breaks down how AI can now simulate virtual cells and tissues, running clinical experiments in minutes instead of years to create truly individualized medicine. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Derya Unutmaz is a world-renowned immunologist, systems biologist, and professor at The Jackson Laboratory. With more than 150 scientific papers, he's a leading expert in immune system research and one of the first scientists to pioneer the concept of digital twins for biology. His groundbreaking work uses AI to model how immunity, metabolism, and aging interact—creating new possibilities for personalized medicine, disease prevention, and lifespan extension. Host Dave Asprey and Dr. Unutmaz reveal how AGI will soon outperform doctors, accelerate functional medicine, and optimize human biology far beyond today's standards. You'll learn how the immune system drives inflammation and aging, how to re-engineer it for resilience, and why compounds like GLP-1 and metformin may add years to your life. You'll Learn: • How digital twins will end human drug testing • Why AGI could replace doctors and computer jobs within five years • How AI models immune function, metabolism, and aging • The role of mitochondria and inflammation in longevity • How GLP-1 drugs and metformin extend lifespan • What continuous biological monitoring means for health tracking • How AI is transforming functional medicine and personalized care • Why NAD and energy metabolism are key to human performance They explore how artificial intelligence, biohacking, and systems biology intersect to create a smarter approach to health and longevity. You'll also learn how understanding immune balance, metabolism, and mitochondrial function helps build resilience and extend your lifespan. This is essential listening for anyone serious about biohacking, hacking human performance, and extending longevity through personalized medicine, functional biology, and cutting-edge AI innovation. This is essential listening for anyone serious about biohacking, hacking human performance, improving mobility, and extending longevity. You'll also learn how neuroplasticity, metabolism, and brain optimization all connect to the way you move. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: AI medicine, Digital twins, Functional medicine, Biohacking, Longevity, Immune system, Inflammation, Personalized medicine, GLP-1 therapy, Metformin, NAD boosters, Mitochondrial function, Metabolism, AGI, Clinical trials, Human performance, Aging research, Systems biology, Immunology, Smarter Not Harder Thank you to our sponsors! BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources: • Keep up with Derya's work: https://x.com/derya_?lang=en • Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:25 — Intro 02:26 — AI's Role in Extending Lifespan 02:56 — Regulatory Frameworks and Medical Adoption 05:19 — Problems with the Immune System 08:19 — Chronic Fatigue and Long COVID Research 10:32 — Modern Testing and Multi-Omic Analysis 14:07 — Personal Longevity Strategy and Supplements 15:17 — Understanding Exhausted Cells 23:43 — Personalization in Medicine and AI Analysis 31:35 — Longevity Escape Velocity 36:13 — AI Doctors and Prescriptions 39:55 — Data Quality Concerns in AI Training 43:19 — The Future of Wearable Technology 45:50 — Revolutionizing Education with AI 49:04 — The Future of Higher Education 52:03 — Future of Work and AI Agents See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people don't know that you can improve your eyesight naturally. In this fascinating video, I'll show you how to reverse poor eyesight and say goodbye to other eye problems like eye strain, glaucoma, and cataracts.0:00 Introduction: How to restore eyesight naturally 0:45 What causes poor eyesight? 5:29 Other eye problems 7:12 How to reverse vision problems naturally 11:38 Foods for better eyesight Poor eyesight starts with the cones in your eye. Cones are receptors in the eye primarily used for detecting color, daylight, and fine detail. Cones have the most mitochondria-packed cells in the entire retina. Mitochondrial loss related to aging can affect vision.As you age, you might notice the following stages of vision loss:1. Contrast sensitivity loss2. Need more light3. See more glare in the dark4. Age-related macular degeneration—can't see fine detailCataracts occur when the lens of the eye becomes cloudy. This is often related to diet. Glaucoma is characterized by pressure in the eyes. High doses of vitamin D3 have been found to help reverse glaucoma. Your eyes are very sensitive to blood sugar problems, which is why one of the leading causes of blindness is diabetes. Dr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

In this special masterclass of Skin Anarchy, Dr. Ekta sits down with Jamie Holmes, Chief Brand Officer of Timeline, to rethink skincare through the lens of longevity. Instead of chasing “anti-aging,” Timeline centers skin health span—keeping skin energetic, resilient, and vibrant for as long as possible. Holmes frames aging as a privilege and makes the case for supporting biology, not hiding it.At the heart of the conversation is Urolithin A, the postbiotic behind Timeline's proprietary MitoPure®. You'll hear how this molecule triggers mitophagy—the cellular cleanup that renews tired mitochondria—so skin can generate more energy and recover from stressors faster. After a decade of research in nutrition, Timeline translated the clinically precise dose into topicals, creating a tight edit of formulas that show measurable gains in hydration and elasticity in as little as 15 days.Jamie opens the lab door on formulation philosophy: no label dusting, just actives at proven concentrations, iterated for texture, absorption, and real-world performance. Even the details matter—the sustainable glass and aluminum, hygienic pumps, and that buttery-yellow hue that reflects MitoPure's natural color—turning daily care into a gender-inclusive ritual. The lineup is intentionally minimalist, designed to slip into any routine and serve both biohackers and skincare newcomers who want evidence over hype.If you're curious about mitochondria as the next frontier in beauty—or you're simply ready to trade quick fixes for cellular results—this episode is your guided tour. Tune in to learn how Timeline is redefining beauty with science you can feel and results you can see.To learn more about Timeline, visit their website and social media.CHAPTERS:(0:02) – Introduction and Welcome(1:05) – Redefining Anti-Aging and Skin Health Span(3:30) – Mitochondria and Cellular Function(5:20) – Early Signs of Aging and Skincare Gaps(6:26) – Timeline's Ingredient Integrity and Active Formulations(8:00) – Urolithin A and MitoPure Science(10:23) – Transition from Nutrition to Skincare(14:44) – Product Development, User Experience, and Packaging(20:08) – Longevity Consumer Mindset and Unisex ApproachPlease fill out this survey to give us feedback on the show!Don't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf! Hosted on Acast. See acast.com/privacy for more information.

Mitochondrial health is vital to your body's overall wellbeing and longevity. I've compiled the top treatments that can help you boost and activate your mitochondria if you suspect signs of dysfunction. From best foods, to natural supplements, alternative therapies and exercise, these are the best methods to help your mitochondria heal.    ✅Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/  

EP. 231:  On this episode we're digging into one of the most exciting frontiers in cellular medicine: how Urolithin A, a powerful compound, supports mitochondrial health and slows the effects of aging at the cellular level. If you've been feeling low energy, dealing with inflammation, or noticing your strength and resilience aren't what they used to be, this episode is packed with science-backed insights to help recharge your body from the inside out. My guest today is Dr. Brad Currier, PhD, Manager of Clinical Trials at Timeline, who's leading the way in Urolithin A research. We're talking muscle metabolism, brain health, immunity, and how this prebiotic compound could be a total game changer for longevity and overall vitality. → Head to timeline.com/DRTYNA to get started & Use code DRTYNA at checkout to receive 20% off today!  Topics Discussed: → What is Urolithin A and how does it help mitochondria? → How does Urolithin A support muscle and metabolism? → How are postbiotics, gut health, and GLP-1s connected? → What does Mitopure research show for immunity and brain health? → How can you use Timeline's Urolithin A daily? Sponsored By: →  Head to timeline.com/DRTYNA to get started & Use code DRTYNA at checkout to receive 20% off today!  On This Episode We Cover:  → 00:00:00 - Introduction  → 00:01:19 - Understanding Urolithin A  → 00:05:24 - Mitochondrial health  → 00:09:08 - Mitochondrial lifecycle  → 00:11:08 - Muscular growth & health  → 00:14:21 - Mitopure research  → 00:17:50 - Postbiotics & the gut microbiome  → 00:22:14 - GLP1s & the gut  → 00:26:31 - Gut rehabilitation  → 00:28:03 - Aging  → 00:31:26 - High protein diets & strength training  → 00:34:45 - Aging + muscle strength  → 00:39:34 - Mitopure, HRT, + stacking  → 00:46:21 - Skincare + topicals  → 00:49:25 - Immune health + inflammation → 00:52:37 - Summary  → 00:56:27 - Trying Timeline!  Show Links:  → Dr. Tyna's Strength Corner Further Listening:  → EP. 196 | The Answer Is The Gym | Quick + Dirty → Strength Training Playlist  Check Out Timeline →  Head to timeline.com/DRTYNA to get started & Use code DRTYNA at checkout to receive 20% off today!  Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

306: Today, we're diving deep into some topics that are near and dear to my heart: Mitochondrial health,  brain health, and of course, the gut microbiome. To help us with that, I'm welcoming Catharine Arnston. She shares with us her most recent findings on 2 potent superfoods and how they can be a simple, effective solution for supporting your mitochondria, detoxification, memory, mood, bones, menopause, and so much more.   Sponsored By:  → Energy Bits | Go to https://energybits.com and Use code: DIGESTTHIS at checkout for a 20% off Topics Discussed: → Heavy metal detoxing → Micro vs macro algae → Reversing Dementia → Benefits of spirulina and chlorella → Nutrients in algae → Mitochondrial health  → Ways to support your gut health → Have more bowl movements  → Brain support → Bone support → Menopause support → How algae removes toxins from the body and why we need it As always, if you have any questions for the show please email us at digestthispod@gmail.com. And if you like this show, please share it, rate it, review it and subscribe to it on your favorite podcast app.  Check Out Catharine Arnston: → Energy Bits | Go to https://energybits.com and Use code: DIGESTTHIS at checkout for 20% off  Check Out Bethany: → Bethany's Instagram: @lilsipper → YouTube → Bethany's Website → Discounts & My Favorite Products → My Digestive Support Protein Powder → Gut Reset Book  → Get my Newsletters (Friday Finds) Learn more about your ad choices. Visit megaphone.fm/adchoices

Alternatives to surgery for venous insufficiency; AI “hallucinates” a never-before-seen brain region in crucial test; Vegetarian complains she is prone to falling; Could tinnitus be triggered by electromagnetic fields from lighting, devices? Cannabis derivatives improve sleep where drugs fail; A novel way of treating chronic nasal infections—with snot transplants! Mitochondrial dysfunction found to be the key to heart, brain problems.

You've probably heard the buzz around the mythical and sketchy-sounding synthetic compound known as methylene blue.How is it that methylene blue went from a 19th-century textile dye to a futuristic, cutting-edge mitochondrial-enhancing compound that turns your tongue blue?After surviving freak bouts of carbon monoxide poisoning, black mold exposure and chronic lyme disease, methylene blue earned its spot in my bag of tricks many moons ago. Should it be in yours?With mitochondrial dysfunction affecting a whopping 94% of adults in the U.S., I'd say it's worth a look.We're here with one of the foremost experts and thought leaders integrating intriguing compounds like methylene blue into their practice, Dr. Scott Sherr. While methylene blue is a remarkable tool for healing and performance optimization of the brain and body, it's not right for everyone. Since methylene blue can interact with certain medications and supplements and we're still learning about its effects on the microbiome, it's essential to exercise caution and be intentional about sourcing, dosage, and frequency of use. Dr. Scott is here to separate the truth from the hype. In this episode, you're about to discover:How to improve metabolic and mitochondrial function with low-dose methylene blueHow combining hyperbaric oxygen therapy and high altitude training with methylene blue further enhance performanceHow to dose methylene blue strategicallyAnd much more…Find Dr. Scott Sherr and his work at: drscottsherr.com: hyperbaric consulting, health optimization, medicine consultingtroscriptions.com: high quality methylene blue and supplement stackshomehope.org: Health optimization, medicine and training for practitionersYou can also join Substack as a free or paid member for ad-free episodes of this show, to comment on each episode, and to hit me up in the DM's. Join at abeljames.substack.com. And if you're feeling generous, write a quick review for the Abel James Show on Apple or Spotify. You rock.This episode is brought to you by:Troscriptions - Go to troscriptions.com/WILD or enter WILD at checkout for 10% off your first order.Crowd Health - Go to JoinCrowdHealth.com and use the code WILD at checkout to get started for as low as $80 per month.Manukora - Go to MANUKORA.com/WILD to save 31% plus $25 of free gifts.

Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and one of the most respected longevity researchers in the world, to reveal how NAD+, sirtuins, and DNA methylation clocks can help you hack aging, upgrade your mitochondria, and extend your healthspan. This episode gives you the real science, proven by over 250 studies, behind supplements, nutrition, and biohacking tools that actually work for brain optimization, metabolism, and human performance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You'll learn why NAD+ is a master regulator of mitochondrial health, how DNA methylation clocks accurately measure biological age, and why boosting sirtuin activity improves resilience, neuroplasticity, and recovery. Dr. Guarente shares insider strategies from decades of functional medicine research, including nootropics, targeted supplements, fasting protocols, and diet adjustments from carnivore to Mediterranean that can shift your metabolism toward longevity. Dave and Dr. Guarente explore advanced biohacks like cold therapy, sleep optimization, and ketosis, plus how to balance these interventions with your genetics, lifestyle, and health goals. You'll also hear about the surprising role of homocysteine in brain aging, how to use lab testing to guide your longevity plan, and why resilience is the ultimate measure of health. You'll learn: • How emotional repression affects brain function, metabolism, and decision-making • Tools for nervous system regulation and emotional healing that drive high performance • Why most people fail without emotional intelligence and internal safety • How somatic awareness can optimize your energy, focus, and relationships • The science of fear, trauma release, and how to turn discomfort into growth • How to coach yourself out of stress, shame, and negative self-talk Whether you want to sharpen your brain, protect your heart, or upgrade your energy systems, this is a masterclass in smarter not harder biohacking for a longer, higher-performing life.Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: NAD+ supplementation, Sirtuin activation, DNA methylation clocks, Biological age testing, Mitochondrial biogenesis, Epigenetic reprogramming, Pterostilbene benefits, Nicotinamide riboside (NR), Nicotinamide mononucleotide (NMN), Homocysteine reduction, Oxidative stress repair, Superoxide dismutase (SOD) activation, Functional medicine longevity, Healthspan optimization, Resveratrol bioavailability, Menopause mitochondrial support, Phenylbutyrate and protein folding, High-fat diet longevity studies, Neurodegenerative disease biohacking, INCHIANTI aging study Thank you to our sponsors! Screenfit | Get your at-home eye training program for 40% off using code DAVE https://www.screenfit.com/dave. Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Elysium Website. Use code ‘UPGRADE25' for 25% off the first month of a monthly subscription to any Elysium supplement: https://www.elysiumhealth.com/ • Dave Asprey's Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction to NAD & Sirtuins 0:59 — Intro 7:04 — Animal vs Human Aging Studies 10:07 — Discovery of Sirtuins 14:43 — NAD's Role in Aging 15:34 — Resveratrol vs Pterostilbene 23:13 — Timing NAD Supplementation 36:34 — Diet & Lifestyle Factors 50:05 — Elysium's Basis & Signal 1:00:03 — Future Clinical Trials 1:05:14 — Psychology of Aging & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Want to think faster, remember more, and rewire your brain for high performance? This special archived episode breaks down the real nootropic stack, neuroplasticity tools, and brain optimization protocols Jim Kwik uses daily, plus the biohacking routines that rebuilt his cognition after traumatic brain injury. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with world-renowned brain coach Jim Kwik, bestselling author of Limitless and advisor to billionaires, athletes, and Hollywood performers. After being labeled “the boy with the broken brain” as a child, Jim transformed his life through functional medicine, nootropics, cold therapy, neurorehab, and smart supplementation. He's now the go-to expert on learning how to learn, with cutting-edge insights on memory, speed reading, focus, and cognitive recovery. Together, they reveal the most effective supplements for brain optimization, how to stack smart drugs with sleep optimization, the surprising downside of alpha GPC, and why things like ketosis, mitochondrial support, and even Danger Coffee are essential for modern cognition. You'll also hear why your brain speed depends on your metabolism, the forgotten science of post-traumatic growth, and how to combine breathing, fasting, and cold therapy for massive neuroplasticity gains. Jim also shares his Brain Animal system, a new way to personalize your learning, decision-making, and communication based on your unique cognitive style. From performance to parenting, he shows how your “brain type” influences every part of life and how to hack it for focus, clarity, and flow. This episode is packed with high-impact strategies for biohacking your brain, improving human performance, upgrading memory, and building real resilience using smarter not harder protocols. You'll Learn: • What Jim Kwik takes daily for brain speed, cognition, and mental stamina • The exact nootropics Dave Asprey uses (and the ones he avoids) • How sleep apnea nearly destroyed Jim's performance and how he hacked it • The connection between mitochondria, memory, and metabolism • Why brain inflammation blocks focus and cognitive clarity • When to use cold therapy, hyperbaric oxygen, and stem cells for brain repair • How to know if your brain needs more acetylcholine and what happens if you overdo it • The best biohacking tools for focus, speed reading, learning, and flow state • Why your brain animal determines how you learn, lead, and connect Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keyword Index: Acetylcholine supplements, Alpha GPC vs CDP choline, Post-traumatic growth brain, Stem cells for brain repair, Hyperbaric oxygen therapy for TBI, Brain inflammation supplements, Learning disabilities recovery, Best supplements for neurogenesis, Brain fog biohacks, Brainwave training programs, Smart drug protocols, Cognitive stack routines, Mitochondrial support for cognition, Electrolytes for brain performance, Danger Coffee brain benefits, ADHD nootropics protocol, Sleep apnea and cognition, High dopamine supplements, Brain types and learning styles, Upgrade Labs review Thank you to our sponsors! Generation Lab | Go to http://generationlab.com/, use code Dave20 for $20 off, and see what your body's really doing behind the surface. GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what's in your air. BodyHealth | Go to https://bodyhealth.com/ and use code DAVE20 to save 20% off your first order of PerfectAmino. Resources: • Jim's Website: https://www.jimkwik.com/ • Dave Asprey's Website: https://daveasprey.com • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: • 0:00 — Introduction & Brain Health • 0:47 — Childhood Injury & Struggles • 2:53 — Adversity & Purpose • 6:31 — Nootropics & Optimization • 18:49 — Daily Biohacking Habits • 32:14 — Exercise & Brain Function • 34:21 — Learning & Cognition • 38:06 — Sleep & Resilience • 41:41 — Brain Types Explained • 52:16 — Parenting & Neuroplasticity • 57:19 — Limitless Update & Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.