Podcasts about mitochondrial

Mitochondrial diseases can affect multiple organs, present at any age, and are frequently misdiagnosed. So how can clinicians recognize the signs sooner?On this episode of Top Docs, Jeremy Bonfini welcomes Dr. Heather Gatcombe, board certified radiation oncologist at Emory University, for a powerful conversation on diagnosis, biochemical testing, treatment options, lifestyle considerations, and support resources for families.Whether you are a clinician, caregiver, or advocate, this episode offers insight you will not want to miss.

BUFFALO, NY — February 24, 2026 — A new #research paper was #published in Volume 18 of Aging-US on February 10, 2026, titled “Aging-associated mitochondrial circular RNAs.” Led by first author Hyejin Mun from the University of Oklahoma — with corresponding authors Je-Hyun Yoon from the University of Oklahoma and Young-Kook Kim from Chonnam National University Medical School — the study profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells (PBMCs) from young and old human cohorts and probes how mitochondrial circRNAs and the mitochondrial RNA-binding protein GRSF1 relate to mitochondrial metabolism and cellular senescence. Using total RNA sequencing of PBMCs from young and old donors and complementary cell-based experiments, the authors report that a large fraction of circular RNA junctions originates from the mitochondrial genome, with MT-RNR2 producing the most abundant circular junctions. They show that circMT-RNR2 levels are depleted in older cohorts and in replicative senescence of human fibroblasts, and that the mitochondria-localized RNA-binding protein GRSF1 interacts with both linear and circular MT-RNR2. Loss of GRSF1 reduced circMT-RNR2 levels, decreased mitochondrial TCA intermediates (fumarate and succinate), and accelerated cellular senescence and mitochondrial dysfunction — findings that link mitochondrial circRNAs to mitochondrial energetics and proliferative status in younger cells. “Taken together, our findings demonstrate the existence and possible function of circular MT-RNR2 during human aging and senescence, implicating its role in promoting the TCA cycle.” The authors note key limitations and outline next steps: clarifying the biogenesis mechanism of mitochondrial circular RNAs (including whether trans-splicing contributes), mapping direct interactions between mitochondrial transcripts and metabolic enzymes, and performing mechanistic studies (in vivo and in additional human cohorts) to test how circMT-RNR2 and GRSF1 influence mitochondrial energetics and organismal aging. These follow-ups will determine whether mitochondrial circular RNAs are actionable targets for modulating mitochondrial metabolism or delaying aspects of cellular aging. DOI - https://doi.org/10.18632/aging.206354 Corresponding authors - Je-Hyun Yoon - jehyun-yoon@ou.edu, and Young-Kook Kim - ykk@jnu.ac.kr Abstract video - https://www.youtube.com/watch?v=f8uZ6_tcOHw Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206354 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, circular RNA, MT-RNR2, GRSF1, TCA cycle To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Discover how fasting extends lifespan, lowers insulin and blood sugar, reduces inflammation, regenerates gut cells, and promotes autophagy. Learn the science-backed benefits of fasting and how to implement strategic fasting protocols for metabolic health, cellular repair, and longevity. Nurse Doza breaks down when and how to use fasting as a powerful health tool. FEATURED PRODUCT Mitochondriac, featuring resveratrol with quercetin and methylated forms, is designed to support mitochondrial function and mimic the beneficial effects of fasting. Research shows resveratrol activates the same pathways as fasting—AMPK, SIRT1, and PGC-1α—promoting autophagy, mitochondrial biogenesis, and cellular repair. Pairing Mitochondriac with your fasting protocol enhances the metabolic benefits discussed in this episode, making fasting more sustainable and effective for longevity and energy production.

Struggling with severe brain fog, insomnia, migraines, or POTS symptoms after a viral infection? You're not alone. In this episode, Dr. Alison shares her personal experience with post-viral cognitive dysfunction and breaks down the science behind long COVID neurological symptoms, chronic fatigue, and nervous system dysregulation. Discover evidence-based strategies for brain recovery including: -Research on immune dysregulation and neuroinflammation after viral infections -Clinical trials for long COVID cognitive symptoms (baricitinib, low-dose naltrexone, metformin) -Essential nutrients for brain health: NAC, CoQ10, omega-3s, vitamin D, B-vitamins -Why Lions Mane and nootropics help some people but worsen ADHD symptoms in others -Dopamine support and saffron spray for post-viral mood and cognitive issues -Nicotine patches for neuroinflammation (watch: https://youtu.be/S9PHDJCncUI) -Game-changing functional neurology brain exercises that rewire your nervous system -Mitochondrial support, phosphatidylcholine, and anti-inflammatory protocols Whether you're dealing with long COVID, Epstein-Barr reactivation, post-viral MCAS, or POTS, this episode provides actionable recovery strategies grounded in current research. Learn why post-viral brain symptoms persist for months or years and what you can do about it today.

In this episode, I sit down with Daria Mochly-Rosen to explore the powerful role mitochondria play in our energy, brain health, metabolism, and long term resilience. We talk about the science behind sleep, strength training, stress, and nutrition, and how simple daily habits can support better healthspan without falling into burnout or extreme biohacks.We also cover the cultural pressure to hustle nonstop, why slowing down is not a weakness, and how connection, family, and meaningful conversations can actually support your biology. She breaks down the fascinating truth about how we inherit mitochondria, how lifestyle choices influence cellular health, and why it is never too late to start building stronger, more resilient energy from the inside out.→ Leave Us A Voice Message! Topics Discussed:→ What are mitochondria?→ How to boost energy?→ Does sleep affect health?→ Best habits for longevity?→ Are mitochondria inherited?Sponsored By: → Function | Own your health for $365 a year. That's a dollar a day. Learn more and join using my link. Visit https://www.functionhealth.com/bewellbykelly and use gift code BEWELL25 for a $25 credit toward your membership→ Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com.→ Timeline | Support your cells and how you age with Mitopure® Gummies from Timeline. Visit https://timeline.com/KELLY and save up to 39% off your Mitopure® Gummies.→ Fatty 15 | Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to https://fatty15.com/KELLY15 and using code KELLY15 at checkout.Timestamps: → 00:00:00 - Introduction→ 00:01:57 - What are mitochondria?→ 00:02:48 - Mitochondria in each cell→ 00:03:46 - Krebs cycle, ATP + metabolism→ 00:06:24 - Cellular energy production→ 00:08:22 - Nutrition for energy→ 00:14:08 - Healthy vs refined carbs→ 00:17:05 - Sugar + metabolic health→ 00:19:12 - Fad diets explained→ 00:23:45 - Lifestyle changes for longevity→ 00:30:33 - Stress + mitochondrial health→ 00:35:59 - Mitophagy + autophagy benefits→ 00:40:46 - Glymphatic brain detox→ 00:43:09 - Exercise + movement science→ 00:49:10 - Mitochondrial peptides→ 00:55:16 - MOTS-C peptide benefits→ 00:56:35 - Chronic disease + mitochondria→ 01:02:38 - Reactive oxygen species→ 01:07:36 - Family, connection + health→ 01:12:07 - Fertility + energy health→ 01:15:01 - Building healthy mitochondriaFurther Listening: → The Key to Longevity: Exploring Mitochondrial Uncoupling with Dr. Steven GundryCheck Out Daria:→ Stanford | https://med.stanford.edu/profiles/daria-mochly-rosen→ Linkedin | https://www.linkedin.com/in/daria-mochly-rosen-9733bb198→ Book |

In this episode of the Health Upgrade Podcast, we dive into the fascinating world of mitochondria and their essential role in cardiovascular health and longevity. We break down what makes mitochondria so pivotal, exploring how different “mitotypes” exist across the body and why supporting these tiny energy powerhouses is the real key to long-term health. By connecting the dots between lifestyle, diet, and emerging science, including the groundbreaking concept of mitochondrial transfer, we uncover why keeping your mitochondria healthy may be far more important than focusing solely on cholesterol levels.We also get personal, sharing an eye-opening story about rethinking cardiovascular risk and statin use, advocating instead for everyday actions like consistent exercise, whole foods, and limiting processed sugars and seed oils. We walk you through how your body can actually repair and revitalize its mitochondria with the right changes, discuss the latest on supplements like urolithin A and spermidine, and shed light on the new frontiers of mitochondrial transplantation for harder-to-treat heart conditions.If you found these insights valuable, be sure to share this episode with someone who's serious about optimizing their health and longevity. Stay tuned for more practical wisdom and the latest science. Let's all step up our health game together!Dr. Navaz HabibEmail: podcast@healthupgraded.comFacebook: https://www.facebook.com/DrNavazHabib/Instagram: https://www.instagram.com/drnavazhabib/LinkedIn: https://ca.linkedin.com/in/drnavazhabibJP ErricoInstagram: https://www.instagram.com/thevnsguy/LinkedIn: https://www.linkedin.com/in/jp-errico-097629aa

Is this you... You're fit. You train consistently. You eat "healthy." You're disciplined and driven. So why does your body feel stuck? In this deep-dive rabbit hole episode, Coach Debbie Potts unpacks the missing pieces high performers overlook when results stall in midlife—despite doing all the "right" things. If pushing harder, training more, or cleaning up your diet isn't working anymore, this episode will explain why. You'll learn why: • You can poop every day and still be constipated • Detox often backfires in driven bodies • The nervous system—not willpower—is the master regulator • Mitochondrial energy determines whether you adapt or resist • Aggressive protocols fail when FLOW isn't restored first Debbie shares what she's learning from trusted mentors, cutting-edge research, and real-world pattern recognition to explain why sequence matters more than effort in midlife health and performance. This episode introduces the FLOW Foundation Blueprint™ and the core reframe high performers need to hear: You don't need more discipline. You don't need to try harder. You need safety before stress, structure before clearance, and energy before effort. If you're tired of guessing, stuck in trial-and-error cycles, or frustrated that your body no longer responds the way it used to—this episode is for you.

If you're a high performer living life like a race—training hard, eating "right," optimizing everything—but still feeling inflamed, tired, reactive, or stuck… this episode is for you. In this deep-dive rabbit hole episode, Coach Debbie Potts breaks down the real order of operations for health, performance, and longevity—from the nervous system to lymph, liver, bile, gut, and mitochondria—and explains why drainage must come before flow if you want to age strong, resilient, and metabolically healthy. You'll learn why: Flow is not effort—it's capacity The nervous system is the master switch for digestion, detox, hormones, and recovery Lymph only moves with breathing, movement, hydrated fascia, and parasympathetic tone The liver doesn't "detox" unless bile can package and carry waste out Pooping is the final step of successful drainage—not the first Forcing detox, training, fasting, or hormones without open exits creates symptoms, not healing Using the FLOW Foundation™ framework (Free the Nervous System → Lymph & Fascia → Oxygen & Blood Flow → Waste Removal), Debbie walks you through the cellular logic of why high performers burn out despite doing everything "right," and how restoring flow turns a stagnant internal swamp back into a clean, moving river. This episode connects the dots between: Nervous system regulation (safety vs. survival) Lymphatic drainage and inflammation Liver detox phases and bile flow Gut motility and hormone clearance Mitochondrial function, blood sugar, and aging capacity If you're ready to stop guessing, stop forcing, and start building health from the inside out, this episode sets the foundation for creating your own FutureYou Blueprint™—with the right order, for your unique body.

In this episode of the Innovations and Clinical Implementation podcast, hosts Dr. Lexi Gonzales and Tom Blue interview Dr. Sundeep Dugar, a pharmaceutical drug hunter with nearly 40 years of experience in small molecule discovery who serves as the co-founder and Chief Scientific Officer at Blue Oak Nutraceuticals. The conversation focuses on the development of Mitocatalyst, a precision-formulated epicatechin designed to mimic the mitochondrial biogenesis normally triggered by exercise. Dr. Dugar reveals his breakthrough discovery that exercise-induced Reactive Oxygen Species (ROS) signal the mitochondria to produce a specific steroid—11-beta hydroxyprogesterone—and explains how Mitocatalyst utilizes nanomolar doses of epicatechin to molecularly mimic this steroid, distinguishing it from high-dose antioxidant protocols that paradoxically blunt these beneficial signals. The discussion uses the metaphor of building a "fireplace" (mitochondria) to burn "firewood" (nutrition), positioning the supplement as a critical intervention for aging patients or those unable to exercise. For access to episode resources: https://sites.google.com/ovationlab.com/innovationsinclinicalimplement/home

Just a half teaspoon of this natural anti-inflammatory acts as a potent ibuprofen substitute for inflammation and pain relief. Discover the best home remedies for pain and inflammation, and learn how to address inflammation at the root. 0:00 Introduction: Natural ibuprofen substitute 0:18 Curcumin, the natural anti-inflammatory 1:58 Pain relievers and ibuprofen comparison 2:08 Ibuprofen effects 3:25 Turmeric as a natural remedy vs. ibuprofen 4:32 More natural pain relief alternatives 6:15 Triggers of pain and inflammation8:25 Preventing inflammation Turmeric contains a potent compound called curcumin that can naturally alleviate pain and inflammation.There are 4 biochemical pathways that act as “master switches” to turn pain and inflammation up or down:1. Pain and inflammatory factory2. Master inflammation on-switch3. Inflammation megaphone 4. Backup inflammatory alarm system Many inflammatory treatments do not address all four pathways. Ibuprofen is great at turning the pain and inflammation switch off, and does so very quickly. Unfortunately, this pathway protects the stomach and kidneys, so ibuprofen can cause stomach ulcers and kidney issues. It also doesn't address the other inflammatory pathways, which is why people often have to take it repeatedly. Tylenol works in the brain, affecting the central nervous system, but does not relieve any inflammation. Similar to ibuprofen, aspirin works on the first inflammatory pathway, which can also affect your stomach.Turmeric affects 3 out of the 4 inflammatory pathways! A double-blind randomized controlled study found that taking 1500 mg of turmeric with black pepper produced results comparable to ibuprofen without the side effects. Extra-virgin olive oil mimics ibuprofen's effects at the molecular level. Try adding it to your salad regularly! Ginger and omega-3 fatty acids also work to reduce inflammation. Boswellia targets the 5-LOX pathway, also known as the backup inflammatory alarm system.There are 5 primary causes that flip the inflammatory switches on, leading to pain and inflammation in the body. By addressing the root cause, you can correct the pain rather than simply managing it. The following 5 factors turn on all of the inflammatory switches:1. Insulin resistance2. Mitochondrial damage3. Chronic oxidative stress4. Leaky gut5. Chronic infectionsTo prevent inflammation and address the root cause, try the following:• Low-carb diet • Eliminate ultra-processed foods• Intermittent fasting/prolonged fasting• Magnesium, vitamin D3, zinc, omega-3sDr. Eric Berg DC Bio:Dr. Berg, age 60, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the Director of Dr. Berg Nutritionals and author of the best-selling book The Healthy Keto Plan. He no longer practices, but focuses on health education through social media.Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients, so he can focus on educating people as a full-time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose, and it is not a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.   Use code NAT10 for 10% off products at https://alchemiqlabs.com/   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02   Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.   BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20.   Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

What if a simple molecule could help you sleep better, recover faster, and potentially extend your life?ESS60 is no longer just a secret for biohackers. This emerging compound is gaining significant attention for its unique ability to combat oxidative stress and improve overall health.In this episode, Chris Burris, Founder and Chief Scientist of My Vital C, explains how this Nobel Prize-winning molecule works and why it holds incredible promise in the longevity space. With over 30 years of experience, Chris delves into the science and numerous studies behind ESS60, its groundbreaking ability to extend the lifespan of rats by 90%, and its fascinating potential for humans in the fight against aging.If you're ready to optimize your health and longevity, tune in now.Episode Timeline:00:00 – Episode Preview01:02 – Welcome to the Smart Nutrition Made Simple Show02:12 – Meet Chris Burris, Founder of My Vital C03:30 – What is ESS60? The Nobel Prize-winning molecule05:00 – ESS60's industrial uses before health applications06:45 – The discovery of ESS60's surprising health benefits08:00 – Wistar rat study and its 90% lifespan extension09:30 – From industrial use to health supplement11:00 – Early biohacker interest in ESS6012:00 – Discussing ESS60's safety and initial hesitations13:45 – ESS60's impact on energy and sleep improvements15:30 – The role of oxidative stress and aging17:00 – ESS60's antioxidant power compared to vitamin C18:30 – Mitochondrial health and exercise recovery20:00 – How ESS60 interacts with mitochondria21:30 – Real-world testimonials of ESS60's benefits25:00 – Where to find ESS60 and access the exclusive discount27:00 – Final thoughts on ESS60 and its longevity potentialConnect with Chris Burres and learn more about ESS60:Exclusive Discount for SNMS ListenersGet a special discount by visiting My Vital C - Body Systems and using the code SYSTEMS at checkout.Chris Burres' BookLive Longer and Better by Chris BurresAvailable through My Vital C Website and major book retailers.Autographed copies available for an additional $10. 100% of the $10 fee goes to Operation Underground Railroad, supporting the fight against child trafficking.ESS60 Products Mentioned in This Episode

If you're noticing changes in your skin — dryness, fine lines, faster wrinkling — you might be blaming age. But what if the real cause is happening… in your gut? In today's deep-dive episode, I uncover how my skin was the messenger, alerting me to deeper internal dysfunction I could only see through testing — not guessing. I take you behind the scenes of my own:

Broadcast from KSQD, Santa Cruz on 1-15-2026: An emailer from Switzerland asks about fluorescein angiography requested before her first retina appointment. Dr. Dawn suspects protocol-based medicine screening for macular degeneration and suggests negotiating to see the doctor first given her different reason for seeing a retinal specialist. She encourages patients to maintain agency in medical settings. An emailer asks about creatine supplements. Dr. Dawn notes it helps muscle development in people doing weight training at 3-5 grams daily, but does nothing for aerobic-only exercisers. Claims about cognition and mood lack solid research. She advises against high-dose "loading," and cautions that creatine causes fluid retention problematic for congestive heart failure and should be avoided with stage 3 or higher kidney disease. Dr. Dawn reminds listeners it's not too late for flu shots, noting this season's H3N2 strain emerged after vaccine formulation was finalized. She laments mRNA vaccine research defunding, as that technology allows rapid reformulation. She describes organoids—tissues grown from stem cells that self-organize into primitive organ structures, enabling rapid drug screening without animal testing. Stanford researchers created assembloids by placing four neurological organoids together that spontaneously connected and built the ascending sensory pain pathway, offering new approaches to studying chronic pain. Dr. Dawn explains research showing satellite glial cells transfer healthy mitochondria to spinal sensory neurons through tunneling nanotubules. When this transfer fails, neurons fire erratically causing pain. Infusing healthy mitochondria into mouse spinal columns cured peripheral neuropathy—suggesting future periodic infusion treatments for humans. She reports Texas A&M researchers created "nanoflowers" from molybdenum disulfate that double stem cell's mitochondrial production, potentially supercharging regenerative medicine for conditions including Alzheimer's and muscular dystrophy. A caller asks about flu vaccines with egg allergy. Dr. Dawn explains that his gastrointestinal reactions to eggs differ from dangerous IgE allergies causing hives or anaphylaxis—GI intolerance doesn't preclude vaccination. Dr. Dawn reveals that 20 years of Parkinson's research followed a false lead. MRI showed increased iron in patients' brains, prompting iron chelation trials—which worsened symptoms. The problem: MRI detects paramagnetic ferric iron (stored, inert) not ferrous iron (biologically active). Patients accumulate useless ferric iron but are deficient in usable ferrous iron. Earlier 1980s studies showing that iron supplementation helped were ignored and abandoned prematurely. She suggests Parkinson's patients discuss iron supplementation with neurologists. She will post the link in the resources page on her website. A caller concerned about early Parkinson's describes tremors and balance problems in darkness. Dr. Dawn suggests darkness-related symptoms sound more like peripheral neuropathy than Parkinson's, recommending neurological examination and screening for diabetes, B vitamin deficiency, or heavy metal exposure. She confirms that sedentary lifestyle reduces mitochondrial production while progressive exercise builds both muscle and mitochondria.

As you age, your thymus produces fewer newly formed cells responsible for responding to unfamiliar pathogens, reducing your immune system's adaptability. This shift, combined with persistent inflammation, defines the core features of immune aging Urolithin A, a postbiotic compound, stimulates mitochondrial renewal in aging immune cells. A recent study shows it can increase naïve-like T cells and strengthen immune surveillance in just four weeks of supplementation Clinical findings show that urolithin A boosts mitochondrial renewal pathways, increases markers linked to mitochondrial biogenesis, and improves immune cell metabolism Beyond immune health, studies reveal that urolithin A influences cancer pathways, enhances muscle strength and endurance, improves fatty liver markers, and reshapes metabolic signaling involved in obesity and insulin resistance Beyond using urolithin A, you can also support your mitochondria by lowering linoleic acid intake, eating the right carbohydrates, limiting environmental toxins, and supporting NAD⁺ production with niacinamide

Just two Brazil nuts daily deliver 1000% of the selenium you need. Learn about the benefits of selenium for your immune system, fertility, and overall health, and why Brazil nuts are the best source of this important trace mineral.

Ever feel a quiet kind of panic creeping up in midlife? The feeling that even though you're showing up for everything, you feel empty inside?  This episode is a powerful reminder that you don't have to live with this feeling forever… better yet, it's absolutely reversible.  We're diving into how lifestyle medicine and cellular energy (hello, mitochondria!) are at the epicenter of how you feel, think, and show up every day.  You'll learn why those mood shifts, energy crashes, and feelings of overwhelm actually make sense — and more importantly, what to do about them.  Then, we're going back to the basics as I'm sharing my top 10 foundational lifestyle adjustments to help you rebuild energy and vitality without extreme plans or pressure.  If you're ready to feel like yourself again, start with one simple change and press play — your midlife health reset begins here!  IN THIS EPISODE Navigating the drastic changes in ALL aspects during midlife  What those little powerhouses– the mitochondria– really do How to track metabolic trends before they spiral out of control The benefits of efficient cycle and symptom tracking  The best ways to stabilize your blood glucose and insulin levels  Why strength training, movement, and protein are a MUST  Choosing the RIGHT supplements to support your body  Considering HRT as a beneficial support in midlife  Why your sleep matters more than you think  How to get started with these simple lifestyle must-dos  QUOTES “Lifestyle medicine is mitochondrial medicine. The reason why lifestyle habits like nutrition, sleep, movement, circadian rhythm optimization, even stress support actually work is because they nourish your mitochondria and they optimize your cellular energy.” “What is one simple lifestyle shift you can make that will help your mitochondria produce more energy tomorrow? Choose one. Commit to it for 7 to 10 days and watch what shifts.” RESOURCES MENTIONED Sign up for my 7-day Hormone & Metabolism Jumpstart https://drmariza.com/jumpstart Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ RELATED EPISODES  710: Kickstart Your New Year: How One Simple Habit Can Transform Your Life, Health, and Mindset 704: Hormone Intelligence for Women in Midlife: How to Thrive Through Perimenopause with Dr. Aviva Romm 690: The Perimenopause Revolution: Why midlife isn't the end — it's the beginning of your most energized, powerful, and vibrant self 686: Your Second Puberty Explained: What's Really Happening to Your Body in Perimenopause 

Longevity isn't just about what you eat or how you train—it's really more about whether you believe your body is worth investing in. On this episode of The Dr. Hyman Show, I'm joined by my longtime friend and colleague Dr. Gabrielle Lyon to explore why muscle may be one of the most overlooked drivers of long-term health. We focus on practical, accessible ways to build strength as you age, and why muscle plays a much bigger role in your health than most people realize. We explore: • How strength training supports your blood sugar and metabolic health, beyond what the scale can show • Why muscle quality—not weight—is a stronger predictor of long-term health • How building strength helps you stay mobile, capable, and resilient as you age • What most people miss about protein and muscle health Aging well is something you can actively support, starting with how you care for your body today. And strength is one of the most powerful places you can begin. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, PerfectAmino, BIOptimizers, Mau Nui, Made In Cookware and BON CHARGE. Receive 35% off off a subscription at timeline.com/drhyman. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Learn more about the health benefits of venison and how to get yours, head over to mauinuivenison.com/hyman. Head to madeincookware.com and use the code HYMAN for 10% off your order. Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off. (0:00) Introduction and Dr. Gabrielle Lyon's background (1:00) Protein's importance across ages and muscle benefits (3:28) Muscle: A neglected organ and its metabolic roles (8:01) Assessing muscle quality and functional health (13:09) Resistance training and muscle rejuvenation strategies (19:33) Muscle's immune and hormonal functions (22:29) Myokines and body composition analysis (26:17) Strength training and innovative techniques (32:05) Muscle as the organ of longevity and protein's significance (38:12) Dietary guidelines and protein requirement debates (48:08) Amino acids, protein turnover, and intake strategies (59:48) Metabolic flexibility and creatine's benefits (1:00:21) Sponsor: Timeline's research on urolithin A (1:02:20) Mitochondrial health and muscle-centric medicine (1:08:14) Muscle health's mismatch with chronic diseases (1:10:20) Dr. Lyon's longevity practices and quickfire questions (1:16:03) Strength's importance during menopause and cold exposure (1:18:51) Dr. Lyon's career highlights and resources (1:20:17) Closing remarks and disclaimers

"Poor egg quality" is not a diagnosis. It's where clinics stop looking. If you've been told you have poor egg quality after failed IVF, low AMH, embryo arrest, or recurrent pregnancy loss, this episode will change how you understand that label and what to do next. Here's the truth most women are never told: poor egg quality is not directly measured. It's a conclusion clinics infer based on age, embryo grading, or how your ovaries responded to stimulation. When IVF fails, that label often becomes the end of the conversation instead of the beginning of a deeper investigation. In this episode, I break down the five physiological patterns we see repeatedly in women with low AMH, failed IVF, embryo arrest, and pregnancy loss and why correcting these patterns can lead to pregnancy even when AMH does not change. In this episode, you'll learn: Why "poor egg quality" is a label, not a test result and what clinics are actually inferring How gut and vaginal microbiome stress drive inflammation and impair nutrient absorption critical for egg development Why mineral depletion disrupts mitochondrial energy, hormone signaling, and cellular communication in the ovary How blood sugar instability and circadian disruption interfere with ovulation and progesterone Why nervous system overload and HPA-axis patterns affect immune balance, implantation, and early embryo development I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally. For over a decade, my team and I have reviewed hundreds of failed IVF cases and helped couples improve pregnancy outcomes naturally and alongside IVF. We specialize in low AMH, high FSH, diminished ovarian reserve, premature ovarian insufficiency, and recurrent pregnancy loss using functional testing and personalized fertility strategies. This episode is for you if: You were told you have poor egg quality with no clear explanation why IVF failed, embryos stopped growing, or all embryos tested were abnormal You don't want another medication tweak or repeated protocol, you want answers

Are you exhausted all the time? In this solo episode, Darin breaks down why so many people feel chronically exhausted despite eating clean, exercising, and "doing everything right." He explains how modern life disrupts mitochondrial function, circadian rhythm, stress signaling, and nutrient availability, and why fatigue is not a personal failure, but a biological signal. This episode offers a grounded, practical roadmap to restoring energy by realigning your environment, habits, and daily rhythms with how the body is actually designed to function.     What You'll Learn in This Episode: Why chronic fatigue is exploding—even among healthy, active people How mitochondria do far more than "make energy" The role of circadian rhythm, light exposure, and timing in energy production Why stress, overtraining, and modern lifestyles drain cellular energy How emotional suppression and unexpressed stress affect vitality The difference between forcing energy and allowing energy Simple daily practices that support mitochondrial repair How breathwork, stillness, and social connection restore resilience Why nutrition alone isn't enough without rhythm and recovery How to realign your biology with the modern world     Timecodes 00:00:00 – Welcome to SuperLife and the intention behind this episode 00:00:32 – Sponsor: TheraSage and natural frequency-based healing 00:02:10 – Happy New Year + why this conversation matters now 00:02:37 – Are you exhausted even though you're "doing everything right"? 00:03:26 – The modern energy crisis and rising chronic fatigue 00:04:12 – Why surface-level health advice no longer works 00:04:27 – Mitochondria: more than energy factories 00:04:59 – Circadian misalignment, EMFs, and modern stressors 00:05:36 – Overtraining, stress load, and lack of recovery 00:06:00 – Fatigue as a signal, not a lack of discipline 00:06:18 – How artificial light disrupts internal clocks 00:07:25 – Discipline as alignment with natural rhythms 00:07:36 – Emotional release, primal expression, and energy recovery 00:08:47 – Why "why am I tired all the time?" is exploding online 00:09:24 – The mitochondria as environmental sensors 00:10:06 – Stress signaling, thoughts, and cellular energy flow 00:11:18 – Breathwork and slowing the nervous system 00:12:24 – Social connection and low-stress signaling 00:13:02 – Sponsor: Bite toothpaste and eliminating plastic exposure 00:15:19 – Morning sunlight and circadian priming 00:15:52 – Reducing artificial light at night 00:16:15 – Nutrients that support mitochondrial function 00:17:29 – Sleep timing, consistency, and repair 00:18:20 – Evening routines and melatonin protection 00:19:46 – Small daily steps compound into real energy 00:20:17 – Antioxidants, inflammation, and recovery 00:20:49 – Training smarter, not harder 00:21:31 – Breathwork, sauna, and recovery rituals 00:22:26 – Nutrition, protein, and polyphenols 00:24:37 – Five daily energy takeaways 00:25:24 – Energy is permitted, not forced 00:26:03 – Listening to the body and closing reflections 00:26:49 – SuperLife Patreon and community support     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Fatigue isn't failure. It's feedback. When your environment, timing, and signals align, your biology remembers how to thrive."     Bibliography/Sources: Ames, B. N. (2006). Low micronutrient intake may accelerate the degenerative diseases of aging through allocation triage. Proceedings of the National Academy of Sciences, 103(47), 17589–17594. https://doi.org/10.1073/pnas.0608757103 Bass, J., & Takahashi, J. S. (2010). Circadian integration of metabolism and energetics. Science, 330(6009), 1349–1354. https://doi.org/10.1126/science.1195668 Gooley, J. J., Chamberlain, K., Smith, K. A., Khalsa, S. B., Rajaratnam, S. M., Van Reen, E., Zeitzer, J. M., Czeisler, C. A., & Lockley, S. W. (2011). Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. The Journal of Clinical Endocrinology & Metabolism, 96(3), E463–E472. https://doi.org/10.1210/jc.2010-2098 Kreher, J. B., & Schwartz, J. B. (2012). Overtraining syndrome: A practical guide. Sports Health, 4(2), 128–138. https://doi.org/10.1177/1941738111434406 Meeusen, R., Duclos, M., Foster, C., Fry, A., Gleeson, M., Nieman, D., Raglin, J., Rietjens, G., Steinacker, J., & Urhausen, A. (2013). Prevention, diagnosis, and treatment of the overtraining syndrome: Joint consensus statement of the European College of Sport Science and the American College of Sports Medicine. European Journal of Sport Science, 13(1), 1–24. https://doi.org/10.1080/17461391.2012.730061 Panda, S. (2016). Circadian physiology of metabolism. Cell Metabolism, 23(6), 1152–1163. https://doi.org/10.1016/j.cmet.2016.06.005 Picard, M., Juster, R. P., & McEwen, B. S. (2014). Mitochondrial allostatic load: Putting the 'gluc' back in glucocorticoids. Nature Reviews Endocrinology, 10(5), 303–310. https://doi.org/10.1038/nrendo.2014.22 Picard, M., & McEwen, B. S. (2018). Psychological stress and mitochondria: A systematic review. Psychosomatic Medicine, 80(2), 126–140. https://doi.org/10.1097/PSY.0000000000000544 Picard, M., McElroy, G. S., & Turnbull, D. M. (2015). Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress. Proceedings of the National Academy of Sciences, 112(48), 14920–14925. https://doi.org/10.1073/pnas.1518223112 Reiter, R. J., Rosales-Corral, S., Tan, D. X., Acuna-Castroviejo, D., Qin, L., Yang, S. F., & Xu, K. (2017). Melatonin as a mitochondria-targeted antioxidant: One of evolution's best inventions? Journal of Pineal Research, 62(1), e12394. https://doi.org/10.1111/jpi.12394 Scheer, F. A., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009). Adverse metabolic and cardiovascular consequences of circadian misalignment. Proceedings of the National Academy of Sciences, 106(11), 4453–4458. https://doi.org/10.1073/pnas.0808180106 Straub, R. H. (2017). The brain and immune system prompt energy shortage in chronic inflammation and ageing. Nature Reviews Rheumatology, 13(2), 74–79. https://doi.org/10.1038/nrrheum.2016.213 World Health Organization. (n.d.). Micronutrient deficiencies. World Health Organization. https://www.who.int/health-topics/micronutrients

Today's episode features guest host Michael Upshall (guest editor, Charleston Briefings) who talks with Michele Frison, Postdoctoral Research Assistant at the MRC Mitochondrial Biology Unit at the University of Cambridge. Michele is originally from Italy and completed his PhD at UCL in England with a focus on cell biology. He defines himself as a cell biologist and biochemist, and much of his current research specializes in cell and mitochondrial biology, aging and disease.  The Mitochondrial Biology Unit is part of a larger infrastructure that runs clinical trials for rare diseases. Michele says the process is very slow, taking up to a decade or so, but that he has been fortunate enough to have made a recent discovery that could well lead to clinical trial: the protein target that he's worked with is actually a target for drugs that have already passed phase one clinical trials and are now passing phase two for Parkinson's disease. If the research he has done in models replicates in humans, then it could well lead to a drug for diseases that affect one in 8,000 humans. Michele also talks about the disconnect between the public understanding of science and scientific practice, research culture and competition, open science and the review process, and the vast amount of literature that scientists have to keep up with, as well as his views on the use of AI and social media in his field. The video of this interview can be found here: https://youtu.be/ri_djNwi1jw Social Media: LinkedIn: https://www.linkedin.com/in/mupshall/ https://www.linkedin.com/in/mkfrison92/ Twitter: Keywords: #UniversityOfCambridge #MBU #LifeSciences #OpenScience #BiomedicalResearch #Research #OpenResearch #ResearchCulture #CellBiology #MitochondrialBiology #PostDoc #ScientificPublishing #PeerReview #LibraryTechnology #Innovation #career #scholcomm #ScholarlyCommunication #libraries #librarianship #LibraryNeeds #LibraryLove #ScholarlyPublishing #AcademicPublishing #publishing #LibrariesAndPublishers #podcasts

Dr. John Cramer, 92-year-old nuclear physicist, discusses participating in the first mitochondrial transplant trial for aging and his longevity theory.Dr. John Cramer is a 92-year-old emeritus professor at the University of Washington who has spent decades researching nuclear physics and quantum mechanics. Now, he's turned his attention to longevity, and he's not just theorizing. Dr. Cramer is participating in Mitrix's groundbreaking mitochondrial transplantation trial, which aims to replace damaged mitochondrial DNA with healthy versions grown in bioreactors.In this conversation, Dr. Cramer explains why he believes mitochondrial dysfunction is the root cause of aging, not just another hallmark. He discusses how energy depletion cascades into all other aging symptoms, why previous interventions like telomere extension haven't delivered, and what markers will be tracked throughout his trial. He also shares his personal longevity protocol, including rapamycin, senolytics, and hyperbaric oxygen therapy.This is one of the first detailed discussions of autologous mitochondrial transplantation for aging in humans.

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Arianne: Hi Dr. Cabral, First, I want to say thank you for all of your resources! I start every day with your podcast - it is truly the best out there! My question is regarding the medication, Leucovorin, and its use in treating Autism. I have a 3 year old son who is non-verbal and is moderately Autistic. His pediatrician has prescribed Leucovorin on a titration schedule where he will be monitored for its effects. To note my own lab results, I have MTHFR, high levels of mercury and aluminum, low electrolytes/minerals, anemia/low ferritin, and gut issues - likely these were passed along to my son. I plan to have him complete the labs now that he is old enough. What is your advice on Leucovorin and its safety & efficacy, also should I be concerned with potential fillers and aluminum in the drug?       Sheena: Hi Dr C! Hope you and your team are well. I was just wondering if all bovine collagen has protein in it, even if it doesn't say it on the label? And if so, does the protein count towards my daily protein intake? Thank you so much in advance for answering!                                                                                                                                                                      Jonny: Hello Dr. Cabral, Recently done some mitochondrial testing and found that my complex 2+3 are operating at 16% activity, and complex 2 at 58%, so there unable to turn substrate into energy efficiently. I'm wondering if you have any advice. Currently dealing with CIRS, Sibo/dysbiosis/chronic stress/Trauma. Non starchy carbs make me jittery, as well as stressors in general, but it's not blood sugar, as I've worn monitors and my levels seem fairly ideal. I think it's the CIRS jitters, shakiness that I've heard you speak of. I just got your new book, so I'm going to read through that for any tips. Already taking adrenal soothe, working with a therapist, doing my best to lower the stressors in my life. I know 90-120 days for red blood cell/mitochondrial turnover, so things can take time. Thanks                            Anonymous: Hi Dr. Cabral, I've heard conflicting advice on cold plunging for people with high stress or adrenal dysregulation. How to you determine if cold exposure if supportive or not. Thanks!                                                                           Sarah: I'm curious about histamine intolerance and allergies. why do some people suddenly develop reactions to something that haven't had all their lives. I used to not be allergic to horses for instance, I could ride them when I was younger, but now I can't even be in the same room with someone who has been around them. Thanks for your help.                  Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3620 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Emerging research shows that human egg cells resist mitochondrial aging, challenging the idea that menopause is irreversible Scientists have successfully reactivated dormant ovarian follicles in women with premature ovarian insufficiency using stem cell strategies and metabolic interventions Mitochondrial health, not egg depletion, may be the key to reversing menopause symptoms and restoring reproductive function Hormones like DHEA, T3, and progesterone, along with nutrients like vitamin A and E, are being studied for their role in rejuvenating ovaries These findings suggest menopause may be a reversible metabolic state — not a permanent shutdown

In this episode, Dr. Rebecca and Dr. Nathan pull back the curtain on this special deep dive that was done for the Thyroid Inner Circle community, exploring the often-missing link in thyroid healing: mitochondrial health. They discuss why optimizing thyroid hormones doesn't always translate into better energy, metabolism, or weight loss and how cellular function plays a major role in how the body adapts, heals, and burns fuel. You'll hear a high-level conversation on the connection between T3, mitochondria, inflammation, blood sugar, gut health, toxins, and modern stressors, along with the necessary action steps and things you can start doing today that influence mitochondrial health and long-term metabolic resilience. If you've improved your labs but still don't feel like yourself, this episode helps explain what may be happening beneath the surface—and why true healing goes beyond hormones alone. Resources mentioned in this episode: ► Mitochondrial support supplements discussed in the podcast: https://us.fullscript.com/plans/drswarren-nathan-warren-1687799355-im8-daily-ultimate-essentials ⭐ Your feedback means so much to me! If you've found this episode helpful, please subscribe and leave a 5-star review—it's one of the best ways to help me share this message with the world.

In this episode, I sit down once again with my most popular guests: Dr. Warren and Dan Schmidt. With over 45 years of clinical experience, Dr. Warren, alongside supplement innovator Dan Schmidt, share the new groundbreaking solutions they have been working on.One of them is a natural testosterone-boosting solution that bypasses injections and risky hormonal shutdown.They also unveil a revolutionary oral delivery method that achieves 85% absorption by activating mucosal uptake. They explain how this delivery system enhances mitochondrial function, boosting energy, hormone levels, and overall well-being.You will also learn about their new Glow topical peptide formula and a complete 24-hour ultimate solution for cellular rejuvenation involving NAD, PQQ, copper peptides, and methylene blue.This brilliant stack supercharges the mitochondria, removes senescent cells, reduces inflammation & oxidative stress, & optimizes sleep.

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Cancer, cardiovascular disease, diabetes, mold toxicity, parasites, and chronic illness are often treated as separate problems—but what if they all stem from the same root cause? David DeHaas, founder of Living Waters Wellness Center, sits down with Alicia Hickson, PA-C, founder of Rama Health, to explore why cancer is not primarily a genetic disease, but a metabolic and mitochondrial disorder driven by inflammation, toxins, mold exposure, parasites, blood sugar dysregulation, emotional trauma, and impaired detoxification pathways.Drawing from the groundbreaking research of Dr. Thomas Seyfried, Alicia explains how damaged mitochondria alter cellular energy production, creating an internal environment where cancer and chronic disease can thrive. This conversation challenges the conventional genetic theory of cancer and reframes healing through the lens of terrain medicine.Throughout the episode, David and Alicia connect the dots between:Mitochondrial dysfunction and cancer metabolismMold toxicity, candida, yeast, and immune system overloadParasites and chronic inflammationEmotional trauma, unforgiveness, and limbic system dysregulationConstipation, lymphatic congestion, and impaired detox pathwaysWhy genetics account for only a small percentage of disease riskWhy conventional medicine often misses root causesWhen integrative and conventional medicine work best togetherDavid shares compelling real-world cases from Living Waters Wellness Center, including parasite cleansing, colon hydrotherapy, emotional release, and rapid shifts in tumor presentation—demonstrating how healing accelerates when the body's internal terrain is restored.Alicia also breaks down advanced clinical tools and therapies, including:Circulating tumor cell testing for cancer monitoringHormone metabolism and estrogen detox pathways (DUTCH testing)Mold and mycotoxin testing strategiesHyperthermia therapy, mistletoe therapy, and immune modulationWhy maintaining remission is just as important as treating cancerThis episode is essential listening for anyone who has been told, “There's nothing more we can do,” aSupport the show Ready for your healing journey?Visit our website: www.LivingWatersCleanse.com Or give us a call at: (208) 378-9911Stem Cell Activation Patches:www.StemCellPatch.netGet your Supplements and Natural Body Products Here:www.livingwaterscleanse.com/supplementsQI-Shield EMF Devices:Protect your whole home or office with a touric shield from EMF's. 1. QI Shield Covers 16'x16' 2. QI Home Covers 50' x 50' 3. QI Max Covers 250'x250'Click on link and enter Livingwaters in discount code section during checkout Magnesium Soaks:Follow us on our socials: Living Waters Wellness CenterBitChute: www.bitchute.com/livingwaterswellnessRumble: www.rumble.com/l...

In this episode, Dr. Jockers explores with Jason Prall how mitochondrial health and the gut microbiome are deeply connected, shaping energy, inflammation, and long-term resilience. You'll learn why mitochondria are far more than energy producers and how their communication drives whole-body health.   In this episode, you'll discover how the microbiome helps translate food into signals that influence mitochondrial function, metabolism, and cellular repair. Jason breaks down why diversity in the gut matters and how everyday choices quietly shape this internal dialogue.   In this episode, you'll hear practical insights on how sleep, light exposure, movement, fasting, and stress act as signals that either strengthen or weaken this mitochondrial–microbiome connection. The conversation leaves space to rethink how small lifestyle shifts can create powerful biological change.     In This Episode:  00:00 Introduction to Human and Mitochondrial DNA 04:06 Deep Dive into Mitochondria and Aging 14:01 Understanding the Gut Microbiome 25:38 Environmental Factors Affecting Health 29:19 Mindfulness and Detoxification 29:55 Impact of Thoughts on Health 31:06 Personalized Health Approaches 31:39 Universal Health Strategies 33:43 Importance of Sleep 37:19 Exercise and Movement 41:07 Fasting and Meal Timing 45:48 Stress and Recovery Balance 48:42 Final Thoughts and Resources     If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday.   Support glowing skin, stronger joints, better digestion, and deeper sleep with Paleovalley's 100% Grass-Fed Bone Broth Protein. Unlike most brands that use hides and skins, Paleovalley slow-simmers real beef bones to extract collagen, glycine, and key amino acids that boost metabolism and reduce inflammation. Each scoop delivers 15 grams of collagen and the clinical dose of glycine for better sleep. Get 15% off at paleovalley.com/jockers.     "Every disease involves mitochondria—when mitochondrial function fails, the body breaks down."      Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Paleovalley Bone Broth Protein: Save 15% on grass-fed bone broth protein at paleovalley.com/jockers.   Connect with Jason Prall: Book:  https://amzn.to/3YC78Wt Website:  humanlongevityfilm.com, beyondlongevitybook.com   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Peptide therapy is turning out to be one of the most exciting frontiers of modern regenerative medicine.Peptides are nature-derived, highly targeted molecules that are already in your body, but when used therapeutically, they can guide healing, enhance function, and even reverse aspects of aging.I walk you through the most powerful peptides, from BPC-157 for tissue and gut repair, to epitalon for extending biological youth, to brain peptides like Dihexa and Cerebrolysin that can help rebuild neural pathways.There's likely a peptide for anything you can think of. Whether it's for boosting your immune system, improving sleep, enhancing mood, supporting weight loss, or regenerating skin and hair.I'll also look at cutting-edge research, including studies on cardiovascular rejuvenation, sexual function peptides like PT-141, and even mitochondrial peptides that fuel your cells' energy engines.

In this powerful episode of Unstress Health, Dr Ron Ehrlich is joined by a true pioneer in healthcare -

Welcome to the PRESSURISED version of episode 64, just the science, none of the waffle PRESSURISED: Cephstravanganza with Professor Kat Bolstad  | The Deep-Sea Podcast | Episode 64 Episode Summary In our newest episode, we join roving reporter Kat Bolstad at the Cephalopod International Advisory Council in Okinawa and hear from some of the most interesting people in Cephalopod research.  Check out our lovely new website where you can find more detailed notes, images and links to the wider reading.   In this episode… Our episode this month is a fascinating collection of interviews from the Cephalopod International Advisory Council Meeting that took place Oct-Nov in Okinawa Japan. Join Kat Bolstad, our roving reporter, as she takes time between bug hunting, seeing her first wild cuttlefish and shaking hands with a new octopus friend to collect interviews with some of the coolest names in Ceph science with a focus on the deep-sea. We hear from 12 Cephalopod experts on a wide variety of topics, including the preferred snacks for cephalopods, the effects of oxygen depletion on egg hatching, water temperature and acidification effects on cephalopod populations, and of course, the correct answer to the viral question: are octopuses actually ALIENS?   Support the show The podcast is self-sustaining (just) thanks to our lovely listeners. Thom and Alan take no money for the show. All money is put back into running it. Here's a link to our page on how to support us, from the free options to becoming a patron of the show. We want to say a huge thank you to those patrons who have already pledged to support us: Elisabeth Grace Diemer Nes Morgan Check out our podcast merch here!   Feel free to get in touch with us with questions or your own tales from the high seas on: podcast@deepseapod.com We'd love to actually play your voice, so feel free to record a short audio note on our brand new answerphone! https://www.speakpipe.com/deepseapodvoicemail Thanks again for tuning in; we'll deep-see you next time! Find out more Social media BlueSky: @deepseapod.com https://bsky.app/profile/deepseapod.com   Twitter: @DeepSeaPod https://twitter.com/DeepSeaPod   Instagram: @deepsea_podcast https://www.instagram.com/deepsea_podcast/   Keep up with the team on social media Twitter:  Alan - @Hadalbloke Thom - @ThomLinley  Instagram:  Thom - @thom.linley  Inkfish - @inkfishexpeditions BlueSky: Thom @thomaslinley.com  Alan @hadalbloke   Reference list Unseen Ocean Collective Unseen Ocean Collective. Unseen Ocean Collective (@unseenoceancollective) • Instagram photos and videos https://bsky.app/profile/unseenocean.bsky.social   Interview Links Kat's Socials Bluesky: @autsquidsquad.bsky.social   Sarah McAnulty Skype a Scientist SkypeAScientist.com  Squidfacts.net     Kristina Fleetwood  Chumash Heritage National Marine Sanctuary Décima lab website   Meg Mindlin Invertibabe    Toni's socials  Twitter,   ResearchGate  ORCID    Toni's Research Group Funcionamiento y Vulnerabilidad de Ecosistemas Marinos | Institut de Ciències del Mar   Other Links Breathe | Mauri Ora | Te Papa @Tailsfromthedeep  Global biodiversity of the genus Ommastrephes (Ommastrephidae: Cephalopoda): an allopatric cryptic species complex  Mitochondrial genome diversity and population structure of the giant squid Architeuthis Spatial ecology of Norway lobster Nephrops norvegicus in Mediterranean deep-water environments: implications for designing no-take marine reserves (MEPS) Diel and seasonal patterns of Nephrops norvegicus (Decapoda: Nephropidae) catchability in the western Mediterranean Antarctic octos as records and predictors of climate-related changes in the Antarctic “Emerging evidence of abrupt changes in the Antarctic environment“  Danna Staaf books  Cephalopod camouflage bibliography on Zotero AUT Lab for Cephalopod Ecology & Systematics aka AUT ‘Squid Squad'   Cephalopod Images and Footage Keishu Asada Instagram CIAC 2025 website, programme, book of abstracts https://www.ryo-minemizu.com/  Keishu Asada Marine Videos Keishu Asada Instagram  @PeterandtheOctopus    Credits Song of the month: Tornado of Souls, by Megadeth, performed by medium-sized Jamieson. Logo image: Photo credit to Peter Morse @PeterAndTheOctopus  Theme: Hadal Zone Express by Märvel    

Migraines affect women three to four times more often than men, largely due to hormonal fluctuations that sensitize the brain's pain pathways and increase vulnerability to stress, poor sleep, and inflammation Estrogen both primes and triggers migraine attacks — high levels heighten sensitivity, while sudden drops before menstruation or after childbirth cause the electrical instability that sparks pain Natural progesterone helps counteract estrogen's pro-inflammatory effects, calming nerve excitability and reducing migraine frequency during hormonally active years Mitochondrial dysfunction is a major driver of migraines; reducing linoleic acid from seed oils and restoring nutrients like magnesium, CoQ10, and B vitamins strengthens your brain's energy supply and resilience Supporting melatonin through morning sunlight, minimizing blue light exposure at night, and maintaining oral and circadian health naturally lowers inflammation, helping prevent migraines and improve overall brain function

Join My Private Group: ⁠⁠⁠⁠https://theaxioncollective.manus.space/⁠⁠⁠⁠Email List: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://huntershealthhacks.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Get My Book On Amazon: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://a.co/d/avbaV48Download⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Peptide Cheat Sheet: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://peptidecheatsheet.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Download The Bioregulator Cheat Sheet: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bioregulatorcheatsheet.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1 On 1 Coaching Application: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamscoaching.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Book A Call With Me: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamscall.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Supplement Sources: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamssupplements.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Storefront: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DY⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Socials:Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/hunterwilliamscoaching/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Video Topic Request: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamsvideotopic.carrd.co/⁠⁠In today's episode, I'm diving into a mitochondrial peptide that almost nobody is talking about yet, but that I believe is going to become a major player in longevity and brain health over the next decade: Humanin.Most people are familiar with mitochondrial peptides like SS-31 or MOTS-c. Humanin is different. It's an endogenous mitochondrial-derived peptide, meaning your body actually makes it naturally, and it plays a critical role in protecting cells, especially under conditions of stress and aging. What really caught my attention with Humanin is that it appears to sit at the intersection of mitochondrial health, neuroprotection, and longevity signaling.In this episode, I walk through what Humanin is, how it was discovered, and why researchers originally became interested in it, particularly in the context of Alzheimer's disease and neurodegeneration. We'll talk about how Humanin functions as a cellular “distress signal” from the mitochondria, how it blocks apoptosis, protects mitochondrial membranes, and helps cells survive oxidative and metabolic stress.I also break down how Humanin differs from other mitochondrial peptides like MOTS-c and SS-31, and why I see it as a uniquely powerful option for brain health and cognitive longevity. We'll look at animal data, observational human data, and fascinating correlations showing that centenarians and their offspring tend to have significantly higher endogenous Humanin levels.From there, I cover potential benefits across brain health, metabolism, cardiovascular function, and lifespan, along with how I personally think about cycling Humanin alongside other mitochondrial peptides throughout the year. Finally, I share my practical thoughts on dosing, cycling strategies, and who I think Humanin is best suited for, especially as we get more focused on preserving cognitive function as we age.If you're interested in mitochondrial health, longevity, brain optimization, or peptide replacement strategies, this episode will give you a solid foundation on why Humanin deserves a spot on your radar.

ReferencesHepatology. 2023 Apr 17;77(5):1654–1669 Nature Communications 2023. v. 14, Article number: 2250 Comprehensive Gut Microbiota 2022, Pages 201-219Javits and Springer. 1953. Santa Baby, MMhttps://music.youtube.com/watch?v=j0oClr4S2oc&si=b_RkrBTm0za9GvoeLennon/McCartney 1969 Oh Darling. Beatleshttps://music.youtube.com/watch?v=erMgpfiOMSU&si=P9E8N1EVGyscakuR

Found My Fitness - Rhonda Patrick: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Get access to more than 200 episodes of my premium podcast (The Aliquot) when you sign up as a FoundMyFitness Premium Member Download my "How to Train According to the Experts" guide One minute of vigorous exercise may be worth up to ten minutes of "moderate" cardio for extending lifespan and preventing chronic disease. In this Journal Club episode, Rhonda Patrick, PhD and endurance athlete Brady Holmer dissect a new Nature Communications study of more than 70,000 adults showing that vigorous intensity is roughly 4–10x more potent than moderate activity for reducing all-cause mortality, cardiovascular events, type 2 diabetes, and cancer outcomes—far beyond the long-standing 1:2 rule embedded in global exercise guidelines. Timestamps: (00:00) Introduction (07:01) What exactly is the 1:2 rule for exercise intensity? (08:18) Calorie burn vs. longevity—origins of the 1:2 rule (11:15) What counts as 'vigorous' exercise, really? (13:35) Where the exercise guidelines fall short (14:19) Can your wearable predict disease risk years in advance? (20:11) Is vigorous activity easier to achieve than people think? (22:47) How researchers avoided the 'healthy user bias' (23:59) Health equivalence ratio—a better way to measure exercise benefits? (25:45) Is vigorous exercise truly 4–10x more effective? (29:55) Can one vigorous minute match an hour of gentle walking? (32:02) Why vigorous activity—not gentle—offers dose-dependent benefits (33:50) Is vigorous exercise 5x better at preventing heart attacks & strokes? (34:24) Why vigorous activity stands out for cancer prevention (34:59) Does zone 2 qualify as vigorous exercise? (36:11) Dose-response comparison—vigorous vs. moderate vs. light activity (37:22) Is vigorous exercise the secret to younger arteries? (43:15) Why aging hearts need intensity (46:09) Can vigorous exercise halt your VO₂ max decline? (47:26) Why moderate exercise alone might not improve VO₂ max (49:21) Is vigorous exercise 10x more powerful at preventing diabetes? (55:48) Mitochondrial biogenesis—why intensity is essential (58:40) Can you directly measure mitochondrial health? (1:00:57) Does vigorous exercise kill circulating tumor cells? (1:07:15) Why vigorous intensity triggers beneficial hormone changes (1:08:05) Can vigorous activity protect older adults from falls? (1:12:36) Does vigorous exercise combat inflammation? (1:14:29) Is high-intensity training the key to a younger brain? (1:16:01) Is vigorous exercise more powerful than we realized? (1:17:50) Can the benefits of vigorous exercise fit into a pill? (1:19:08) How small doses of intensity might extend your lifespan (1:23:15) Do short bursts of vigorous movement match full workouts? (1:27:26) Why your wearable might undervalue short vigorous bouts (1:30:06) Can planned micro-workouts replace traditional gym sessions? (1:35:10) Why exercise guidelines urgently need updating (1:46:35) Does light activity still offer real benefits? (1:49:04) Is vigorous exercise safe for older adults? (1:53:28) Are high-intensity workouts detrimental to female hormones? (1:58:02) Safe vigorous exercise options—even with chronic illness (1:59:05) The 80/20 rule for balancing intensity and recovery (2:01:30) Inside Brady's routine—how much vigorous exercise is optimal? (2:05:17) Can vigorous activity boost kids' brainpower (and grades)? (2:08:14) Are we significantly underestimating vigorous exercise benefits? (2:10:03) Why chasing steps isn't the answer Show notes are available by clicking here Watch this episode on YouTube

ReferencesHepatology.2023 Apr 17;77(5):1654–1669Oncotarget.2017 Aug 22; 8(34): 55967–55983.Can.J.Physiol.Pharmacol. 2025. 103: 208–224 Guerra. DJ 2025. Unpublished LecturesPage, J. 1970 Tangerine LZhttps://music.youtube.com/watch?v=_0Auvlsv860&si=A4mSuCcSwCeF0M4DLennon./McCartney/Harrison. 1966. Rubber Soul lphttps://music.youtube.com/playlist?list=OLAK5uy_lirCIxLpU2odTVLZ_Sbo1wZaeu5IStivs&si=HmFiZGPpBWuz14im Biber , HI. !681 Sonata & in G major C.144https://music.youtube.com/watch?v=kFOD7qM1oNc&si=OiHaskXRsDRbcUDz

This episode covers mitochondrial inheritance.Written notes can be found at https://zerotofinals.com/paediatrics/genetics/mitochondrialinheritance/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

Your muscle isn't just for strength—it's your metabolic organ, your glucose sink, your hormonal stabilizer, and your anti-aging insurance policy. But here's the hard truth: If your protein is low in leucine, hard to digest, or blocked by anti-nutrients, you're putting the brakes on everything you're trying to optimize.

Get access to more than 200 episodes of my premium podcast (The Aliquot) when you sign up as a FoundMyFitness Premium Member Download my "How to Train According to the Experts" guide One minute of vigorous exercise may be worth up to ten minutes of "moderate" cardio for extending lifespan and preventing chronic disease. In this Journal Club episode, Rhonda Patrick, PhD and endurance athlete Brady Holmer dissect a new Nature Communications study of more than 70,000 adults showing that vigorous intensity is roughly 4–10x more potent than moderate activity for reducing all-cause mortality, cardiovascular events, type 2 diabetes, and cancer outcomes—far beyond the long-standing 1:2 rule embedded in global exercise guidelines. Timestamps: (00:00) Introduction (07:01) What exactly is the 1:2 rule for exercise intensity? (08:18) Calorie burn vs. longevity—origins of the 1:2 rule (11:15) What counts as 'vigorous' exercise, really? (13:35) Where the exercise guidelines fall short (14:19) Can your wearable predict disease risk years in advance? (20:11) Is vigorous activity easier to achieve than people think? (22:47) How researchers avoided the 'healthy user bias' (23:59) Health equivalence ratio—a better way to measure exercise benefits? (25:45) Is vigorous exercise truly 4–10x more effective? (29:55) Can one vigorous minute match an hour of gentle walking? (32:02) Why vigorous activity—not gentle—offers dose-dependent benefits (33:50) Is vigorous exercise 5x better at preventing heart attacks & strokes? (34:24) Why vigorous activity stands out for cancer prevention (34:59) Does zone 2 qualify as vigorous exercise? (36:11) Dose-response comparison—vigorous vs. moderate vs. light activity (37:22) Is vigorous exercise the secret to younger arteries? (43:15) Why aging hearts need intensity (46:09) Can vigorous exercise halt your VO₂ max decline? (47:26) Why moderate exercise alone might not improve VO₂ max (49:21) Is vigorous exercise 10x more powerful at preventing diabetes? (55:48) Mitochondrial biogenesis—why intensity is essential (58:40) Can you directly measure mitochondrial health? (1:00:57) Does vigorous exercise kill circulating tumor cells? (1:07:15) Why vigorous intensity triggers beneficial hormone changes (1:08:05) Can vigorous activity protect older adults from falls? (1:12:36) Does vigorous exercise combat inflammation? (1:14:29) Is high-intensity training the key to a younger brain? (1:16:01) Is vigorous exercise more powerful than we realized? (1:17:50) Can the benefits of vigorous exercise fit into a pill? (1:19:08) How small doses of intensity might extend your lifespan (1:23:15) Do short bursts of vigorous movement match full workouts? (1:27:26) Why your wearable might undervalue short vigorous bouts (1:30:06) Can planned micro-workouts replace traditional gym sessions? (1:35:10) Why exercise guidelines urgently need updating (1:46:35) Does light activity still offer real benefits? (1:49:04) Is vigorous exercise safe for older adults? (1:53:28) Are high-intensity workouts detrimental to female hormones? (1:58:02) Safe vigorous exercise options—even with chronic illness (1:59:05) The 80/20 rule for balancing intensity and recovery (2:01:30) Inside Brady's routine—how much vigorous exercise is optimal? (2:05:17) Can vigorous activity boost kids' brainpower (and grades)? (2:08:14) Are we significantly underestimating vigorous exercise benefits? (2:10:03) Why chasing steps isn't the answer Show notes are available by clicking here Watch this episode on YouTube

Episode Summary In our newest episode, we join roving reporter Kat Bolstad at the Cephalopod International Advisory Council in Okinawa and hear from some of the most interesting people in Cephalopod research.    Check out our lovely new website where you can find more detailed notes, images and links to the wider reading. In this episode… Welcome back to the Deep-Sea Podcast, your punk take on all things deep sea!  The Professor is still down under, organizing conferences and recuperating from Old Mate's Classic Aussie Sausage Sizzle, a robust event filled with friends of the podcast and still felt 24 hours later.    Thom is freshly back from another big ocean/small boat adventure, in which the ocean always wins and his stomach always loses… everything. He is also stretching his creative muscles and curating an exciting new museum exhibit called Breathe | Mauri Ora at Te Papa, an examination of science into art by Marshmallow Lazer Feast.    Our episode this month is a fascinating collection of interviews from the Cephalopod International Advisory Council Meeting that took place Oct-Nov in Okinawa Japan. Join Kat Bolstad, our roving reporter, as she takes time between bug hunting, seeing her first wild cuttlefish and shaking hands with a new octopus friend to collect interviews with some of the coolest names in Ceph science with a focus on the deep-sea. We hear from 12 Cephalopod experts on a wide variety of topics, including the preferred snacks for cephalopods, the effects of oxygen depletion on egg hatching, water temperature and acidification effects on cephalopod populations, and of course, the correct answer to the viral question: are octopuses actually ALIENS?   In the news, get ready for updates on: Deep diving manta rays using the ocean bottom to navigate A newly launched AI tool to map the Deep- Sea Bright blue mud filled with fat molecules indicating life in the deep Corals and Crinoids sharing symbionts and cycling nitrogen And an update from the Unseen Ocean Collective about the work they are creating for a show in Juneau Alaska in 2026. On the Discord, we've been busy with: Voting on the Holiday Party movie Started a long overdue ART channel, and a new Pets channel Photo tours of submersibles and Okinawa  Early Holiday celebrations by one of our hosts Great feedback and conversation on our last episode.  Support the show The podcast is self-sustaining (just) thanks to our lovely listeners. Thom and Alan take no money for the show. All money is put back into running it. Here's a link to our page on how to support us, from the free options to becoming a patron of the show. We want to say a huge thank you to those patrons who have already pledged to support us: Elisabeth Grace Diemer Nes Morgan Check out our podcast merch here!   Feel free to get in touch with us with questions or your own tales from the high seas on: podcast@deepseapod.com We'd love to actually play your voice, so feel free to record a short audio note on our brand new answerphone! https://www.speakpipe.com/deepseapodvoicemail Thanks again for tuning in; we'll deep-see you next time! Find out more Social media BlueSky: @deepseapod.com https://bsky.app/profile/deepseapod.com   Twitter: @DeepSeaPod https://twitter.com/DeepSeaPod   Instagram: @deepsea_podcast https://www.instagram.com/deepsea_podcast/   Keep up with the team on social media Twitter:  Alan - @Hadalbloke https://twitter.com/Hadalbloke Thom - @ThomLinley  https://twitter.com/ThomLinley Instagram:  Thom - @thom.linley  https://www.instagram.com/thom.linley/ Inkfish - @inkfishexpeditions https://www.instagram.com/inkfishexpeditions/ BlueSky: Thom @thomaslinley.com https://bsky.app/profile/thomaslinley.com  Alan @hadalbloke https://bsky.app/profile/hadalbloke.bsky.social   Reference list News  Deep-Sea News World's largest rays may be diving to extreme depths to build mental maps of vast oceans China launches AI tool for deep-sea research Fat Molecules in Deep-Sea Mud Volcanoes Reveal How Microbes Survive Extreme Conditions | Discover Magazine Putative promiscuous symbionts in deep-sea corals and crinoids may contribute to nitrogen cycling | Microbiome   Unseen Ocean Collective Unseen Ocean Collective. Unseen Ocean Collective (@unseenoceancollective) • Instagram photos and videos https://bsky.app/profile/unseenocean.bsky.social   Discord Updates Holiday Party! Join Patreon here to get access to the Holiday party!   Interview Links Kat's Socials Bluesky: @autsquidsquad.bsky.social   Sarah McAnulty Skype a Scientist SkypeAScientist.com  Squidfacts.net     Kristina Fleetwood  Chumash Heritage National Marine Sanctuary Décima lab website Meg Mindlin Invertibabe    Toni's socials  Twitter,   ResearchGate  ORCID    Toni's Research Group Funcionamiento y Vulnerabilidad de Ecosistemas Marinos | Institut de Ciències del Mar   Other Links Breathe | Mauri Ora | Te Papa @Tailsfromthedeep  Global biodiversity of the genus Ommastrephes (Ommastrephidae: Cephalopoda): an allopatric cryptic species complex  Mitochondrial genome diversity and population structure of the giant squid Architeuthis Spatial ecology of Norway lobster Nephrops norvegicus in Mediterranean deep-water environments: implications for designing no-take marine reserves (MEPS) Diel and seasonal patterns of Nephrops norvegicus (Decapoda: Nephropidae) catchability in the western Mediterranean Antarctic octos as records and predictors of climate-related changes in the Antarctic “Emerging evidence of abrupt changes in the Antarctic environment“  Danna Staaf books  Cephalopod camouflage bibliography on Zotero AUT Lab for Cephalopod Ecology & Systematics aka AUT ‘Squid Squad'   Cephalopod Images and Footage Keishu Asada Instagram CIAC 2025 website, programme, book of abstracts https://www.ryo-minemizu.com/  Keishu Asada Marine Videos Keishu Asada Instagram    @PeterandtheOctopus    Credits Song of the month: Tornado of Souls, by Megadeth, performed by medium-sized Jamieson. Logo image: Photo credit to Peter Morse @PeterAndTheOctopus  Theme: Hadal Zone Express by Märvel

In this episode, Ben reveals three stupid-simple movements that activate fat loss in under five minutes a day — no gym, no sweating, no burpees. These moves target the three systems that slow down after 40: Lymphatic flow (your body's drainage + detox system) Insulin sensitivity (your fat-storage switch) Mitochondrial activation (your metabolic engine) You'll learn: • Why fat loss is harder after 40 (and what to do instead of “working harder”)• How cross-crawls stimulate lymph flow and full-body circulation• How a squat hold with mini pulses unlocks insulin sensitivity• How wall angels activate mitochondrial-rich postural muscles• Why hormones matter more than calories for sustainable fat loss• How to layer these movements with walking, breathwork, cold exposure, or your existing routine• Why doing them for 14 days straight can create visible changes• How to make the moves harder as your body adapts• Why these movements are especially powerful for those who are sedentary, insulin resistant, or over 40

In this transformative episode of Unleashing Intuition Secrets, Michael Jaco sits down with Dr. Jon Harmon, a leading expert in neurofeedback, copper peptides, and regenerative wellness, to reveal the groundbreaking science behind reversing aging — naturally and powerfully. Dr. Harmon shares his remarkable journey from traditional chiropractic practice to becoming one of the foremost voices in anti-aging therapies. Through profound personal tragedy and deep professional exploration, he discovered the incredible potential of copper peptides, telomere restoration, mitochondrial repair, and LifeWave's X39 phototherapy technology to rejuvenate the body at the cellular level. Michael and Dr. Harmon break down the real science behind: • Copper peptides and their role in regeneration • Telomere length and biological aging • Mitochondrial function and energy production • Cognitive decline and neurofeedback breakthroughs • X39's potential to activate stem cells and restore youthfulness Packed with insights, real-world case stories, and cutting-edge research, this episode reveals what's truly possible when ancient wisdom, modern science, and advanced phototherapy come together. Explore Dr. Harmon's book How to Reverse Aging on Amazon: https://www.amazon.com/How-Reverse-Aging-Comprehensive-Peptides-ebook/dp/B0CK4FKQJ8?ref_=ast_author_dp&th=1&psc=1 Explore with Michael Jaco: https://michaelkjaco.com This is the future of youth restoration — and it's available now. Stay in the love vibrations as you discover what your body is truly capable of. ✨      

A patient arrives at shock trauma with flesh-eating bacteria, limbs appearing unsalvageable. Hours later, after treatment in a massive submarine-like chamber, those same limbs show signs of recovery. This pivotal moment launched Dr. Scott Sherr's journey into the world of hyperbaric oxygen therapy and its untapped potential for metabolic healing.Victoria Field welcomes Dr. Scott Sherr, a board certified internal medicine physician who transformed his practice after witnessing HBOT's dramatic effects during his medical training at University of Maryland's trauma center. Now Director of Integrative Hyperbaric Medicine at Hyperbaric Medical Solutions, Dr. Sherr has pioneered protocols that marry hyperbaric therapy with nutritional optimization and metabolic health strategies.Questions Answered in This Episode: What sparked his interest in branching out into hyperbaric oxygen therapy? Why does he recommend waiting three months before intensive protocols? What is the "sympathetic spiral of doom"? What excites him most about the future of hyperbaric medicine? What's his vision for creating integrated healing ecosystems?This conversation reframes hyperbaric medicine not as a standalone treatment, but as a powerful tool within a comprehensive metabolic optimization framework - one that could fundamentally change how we approach healing and human performance.Learn about Dr. Scherr's work with Troscriptions here.Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here.✅Cowboy Colostrum - Get 25% off when you use code METABOLICLINK at checkout here.✅ Branch Basics - Get 15% off your Premium Starter Kit here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode Lisa Tamati and Dr. Elizabeth Yurth dive deep into immunosenescence, the ageing of the immune system, and how it drives age-related diseases like cancer, infections, and chronic inflammation. They discuss the development of Rejuvenate Pro, a formulation inspired by Lisa's efforts to support her ageing mother's complex health issues. The episode explores the science behind immune decline, key biomarkers, and how Rejuvenate Pro's ingredients target root causes for better longevity. Key themes include: Gut-immune connections Mitochondrial impacts Stem cell activation Practical applications for clinicians and patients. Resources Mentioned: 1000 Immunomes Project (Buck Institute) Dr. David Furman Interviews Dr. Rod Claycomb Podcasts  Aevum Labs Research Papers Rejuvenate Pro by Aevum Labs

In this episode of the Ancient Health Podcast, Dr. Thomas Levy breaks down for us how oxidative stress—driven by toxins, infections, and nutrient deficiencies—is the real driver of aging and disease. Liposomal vitamin C and glutathione can provide rapid relief, support autoimmune conditions, and restore cellular function by replenishing electrons the body loses to toxins. Dr. Levy also highlights how dental infections, especially root canals, can trigger inflammation throughout the body, making oral health essential for anyone dealing with chronic illness. The conversation covers everything from the role of B vitamins and niacin in energy and mental health to methylene blue, nutrient loss from processed foods, and his “Super 8” supplement protocol designed to fight oxidative stress. Dr. Levy discusses how:  Toxins are the root of oxidation All disease patterns are caused by oxidation Root canals and disease are linked  Liposomal's advantage over other nutrient delivery forms Dr. Levy's super 8 supplements for fighting aging and disease:  Vitamin C — central antioxidant, reduces oxidative stress Magnesium — helps lower intracellular calcium (which otherwise increases oxidative stress) Vitamin D — part of his calcium-modulation groupVitamin K — works with D and magnesium to normalize calcium inside cellsNiacin / Niacinamide (Vitamin B3) — fuels the electron transport chain by boosting NAD, supporting ATP productionRiboflavin (Vitamin B2) — supports the ETC (flavin coenzymes)Coenzyme Q10 — critical electron carrier in mitochondrial energy productionMethylene Blue — can bypass parts of the electron transport chain to generate ATP efficiently Get 10% off LivOn Labs entire store of liposomal supplements with code MOTLEY at https://www.livonlabs.com/ Want more of the Ancient Health Podcast? Check out Doctor Motley's YouTube channel! ------  Follow Doctor Motley  Instagram TikTok Facebook Website Follow Dr. Levy https://www.instagram.com/drthomaslevy/?hl=en https://www.tomlevymd.com/ tomlevymd@yahoo.com Buy Dr. Levy's book: The Only Cause of Disease: https://shorturl.at/inbjQ ------  * Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for modules full of his expertise and clinical wisdom on so many health issues, plus bring all your questions to his weekly lives! Explore it free for 15 days at https://www.doctormotley.com/15

278: Your mitochondria isn't just the powerhouse of the cell - it's the CEO holding the key to your longevity. Today I'm joined by dietitian nutritionist Jennifer Scheinman of Timeline Longevity to break down this exciting new area of health science - mitochondrial function and the powerful post-biotic urolithin A. If you've been hearing the buzz about mitochondrial health, Mitopure, or longevity therapies, this episode gives you the science and approach behind it all. → Timeline | Timeline is offering 20% off your order of Mitopure Go to https://timeline.com/REALFOODOLOGY Topics Discussed: → What is urolithin A?  → How does mitochondrial health impact aging? → Can post-biotics like urolithin A enhance the benefits of some foods? → How does urolithin A benefit the skin?  → What supplements can you take to benefit your mitochondria?  Sponsored By: → Timeline | Timeline is offering 20% off your order of Mitopure Go to https://timeline.com/REALFOODOLOGY Timestamps:  → 00:00 - Introduction  → 02:01 - Food First, Supplements Later  → 05:00 - Urolithin A Explained  → 10:00 - Mitochondrial Health + Function  → 20:19 - Perimenopause, Menopause + Fertility  → 22:55 - Studies & Research: Urolithin A  → 29:07 - Mitopure Results  → 32:14 - Aging, Immunity & Brain Health  → 38:18 - Impacts on Skin  → 42:21 - Mitophagy, Hormones & Plant-Based Diets   → 46:00 - Aging  → 49:26 - Mitopure Gummies, Gels & Powders  Check Out Timeline: → Instagram | Timeline Longevity → Instagram | Timeline Skincare  → Instagram | Jennifer Scheinman  Check Out Courtney:  →  LEAVE US A VOICE MESSAGE →  Check Out My new FREE Grocery Guide! →  @realfoodology →  www.realfoodology.com →  My Immune Supplement by 2x4 →  Air Dr Air Purifier →  AquaTru Water Filter →  EWG Tap Water Database Produced By: Drake Peterson

In this powerhouse episode, Darin sits down with Catharine Arnston, founder and CEO of ENERGYbits, to explore one of the planet's oldest and most potent foods — algae. From spirulina's superoxide dismutase to chlorella's detoxifying chlorophyll, Catharine breaks down the science of why these tiny organisms hold the key to longevity, energy, detox, and cellular repair. This episode dives deep into the microbiology of health, uncovering how microalgae could solve both human nutrition and planetary sustainability — and why spirulina may truly be "the food of the future."     What You'll Learn in This Episode [00:00] Welcome and intro — algae near the ocean, Darin's long relationship with chlorella and spirulina [00:01:28] The origins of ENERGYbits and Catharine's passion for transparent, toxin-free sourcing [00:03:19] Why algae isn't just another supplement — it's a whole food category of its own [00:04:07] Nutrient density per calorie — the power of bioavailable vitamins, minerals, and proteins [00:05:02] Understanding macroalgae vs. microalgae — why spirulina and chlorella are the real heroes [00:06:15] Why growing algae in freshwater matters — avoiding ocean toxins and micro-contaminants [00:08:06] The global algae revolution — how sustainable "photo bioreactors" may feed the planet [00:10:30] Quality control in algae production — how ENERGYbits preserves nutrient integrity [00:11:18] Spirulina as offense and chlorella as defense — the ultimate nutrition playbook [00:12:58] Why spirulina fuels performance and chlorella drives recovery [00:13:43] Why "food first" is the future of health — and how over-supplementation misses the mark [00:14:25] Algae's 99% absorption rate vs. supplements' 5–10% — the "orchestra" analogy [00:15:06] Phycocyanin — the blue pigment powerhouse behind spirulina's antioxidant strength [00:17:14] Real food vs. isolates — why nature's nutrient matrix always wins [00:18:18] The UN's endorsement: why spirulina could solve world hunger [00:19:13] Bioavailable plant protein — 64% complete protein by weight [00:21:14] How algae creates and saves energy — digestion efficiency and cellular fuel [00:22:02] The chlorophyll connection — nature's blood builder and detoxifier [00:23:32] Why chlorella is a daily detox essential — heavy metals, toxins, and PM2.5 [00:24:43] Chlorella as your daily "internal shower" — detoxing in a toxic world [00:26:59] The antioxidant that saves your mitochondria — superoxide dismutase (SOD) [00:28:32] How SOD prevents inflammation, disease, and aging — and why we lose it after 40 [00:30:46] Why spirulina is nature's richest source of active SOD [00:32:29] Preserving enzymes — why low-temperature processing is everything [00:33:53] Algae's healing power — stories from Hippocrates and Gerson Institutes [00:35:01] The missing human operating manual — how to truly fuel your cells [00:36:07] The symptom isn't the problem — it's the signal your body's sending [00:37:12] Catharine's origin story — how her sister's breast cancer changed her life forever [00:38:32] Discovering alkalinity — Otto Warburg's cancer research and pH balance [00:40:28] The goldfish analogy — why your body's environment determines your health [00:41:32] How feeding fish algae solved oceanic "dead zones" — the alkalinity connection [00:42:22] Disease as slow imbalance — how poor food slowly drains vitality [00:43:06] Why cellular energy equals cellular wealth — mitochondria as your body's power grid [00:44:36] How chronic disease spirals begin — free radicals, mitochondria, and collapse [00:46:11] The alkaline rescue — how algae restores blood charge and vitality [00:48:23] Real food as communication — how nutrients talk to your cells [00:49:25] The mitochondria-light analogy — why spirulina "turns the lights back on" [00:50:51] Mitochondrial health and mental health — the "Brain Energy" connection [00:52:14] Aging naturally vs. declining unnecessarily — how nutrient density extends life [00:52:58] Spirulina puts nutrients in, chlorella pulls toxins out — the perfect pair [00:53:18] Catharine's 15-year algae experiment — her personal health story [00:54:22] Building ENERGYbits from scratch — Shark Tank, $50k, and unstoppable grit [00:55:07] The "Mother Nature" philosophy — how simplicity and consistency heal [00:56:13] Living in alignment — yoga, sleep, sunlight, and algae as core habits [00:57:09] Listening to intuition — following the whisper of your soul, not the ego's noise [00:59:23] The feather touch of purpose — when you follow your calling, life unfolds [01:00:36] Hitting rock bottom to rise higher — the unseen power of persistence [01:02:22] When helping others heals yourself — Catharine's message of divine reciprocity [01:03:00] Closing reflections — Mother Nature as the ultimate mentor   Thank You to Our Sponsors: Pique Tea: Go to www.piquelife.com/darin to get 20% off all products for life and a free starter kit. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order.     Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only  $7.49/month at https://patreon.com/darinolien     Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com     Find More From Catharine Arnston: Buy Algae at Energy Bits: energybits.com Instagram: @catharinearnston Website catharinearnston.com     Key Takeaway "You didn't get sick overnight — and you won't heal overnight. But you can. The recipe is simple: give your body the ingredients Mother Nature designed — sunlight, sleep, breath, movement, and algae. Algae isn't a supplement. It's food. It's your body's operator manual in disguise."  

Nicotine isn't just addictive—it might be one of the most misunderstood nootropics in modern medicine. In this masterclass, you'll learn how controlled, low-dose nicotine may enhance brain performance, boost neuroplasticity, improve mitochondrial function, and potentially extend lifespan. Host Dave Asprey breaks down the surprising science behind this controversial compound, separating fact from fear—and exposing the real risks that nobody talks about. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You'll discover how nicotine affects neurotransmitters, why it may help with ADHD and focus, and how it compares to other cognitive enhancers like caffeine, nootropics, and even smart drugs. Dave explores how nicotine can be used to hack metabolism, enhance sleep optimization, and support fasting or ketosis protocols—if used properly. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll Learn: • How nicotine affects mitochondria, neurotransmitters, and dopamine signaling • Why nicotine may boost neuroplasticity, memory, and attention span • How low-dose nicotine compares to caffeine, modafinil, and other nootropics • The safest delivery forms (and the ones to avoid) • Whether nicotine supports or hinders longevity and cognitive resilience • How it can be stacked with supplements, fasting, or ketosis • What functional medicine says about chronic use, addiction, and withdrawal This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Nicotine microdosing, Nicotinic acetylcholine receptors, Dopamine and motivation, Cognitive enhancement, Alzheimer's prevention, Neuroinflammation, Mitochondrial function, TNF-alpha reduction, Vagus nerve activation, Longevity biohacking, Nicotine vs smoking, Nootropics, Attention and vigilance, Ketosis and metabolism, Functional medicine, Nicotine patches and gum, Addiction and tolerance, Receptor desensitization, Withdrawal protocols, Deep work performance Thank you to our sponsors! -TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. -HeartMath | Go to https://www.heartmath.com/dave to save 15% off. -Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE. -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 1:27 — History & Background of Nicotine 4:34 — How Nicotine Works 15:12 — Benefits & Research 16:43 — Risks & Who Should Avoid It 21:39 — Delivery Methods & Dosing 26:30 — Conclusion & Next Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.