Podcasts about mitochondrial

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.   Use code NAT10 for 10% off products at https://alchemiqlabs.com/   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02   Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.   BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20.   Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

What if a simple molecule could help you sleep better, recover faster, and potentially extend your life?ESS60 is no longer just a secret for biohackers. This emerging compound is gaining significant attention for its unique ability to combat oxidative stress and improve overall health.In this episode, Chris Burris, Founder and Chief Scientist of My Vital C, explains how this Nobel Prize-winning molecule works and why it holds incredible promise in the longevity space. With over 30 years of experience, Chris delves into the science and numerous studies behind ESS60, its groundbreaking ability to extend the lifespan of rats by 90%, and its fascinating potential for humans in the fight against aging.If you're ready to optimize your health and longevity, tune in now.Episode Timeline:00:00 – Episode Preview01:02 – Welcome to the Smart Nutrition Made Simple Show02:12 – Meet Chris Burris, Founder of My Vital C03:30 – What is ESS60? The Nobel Prize-winning molecule05:00 – ESS60's industrial uses before health applications06:45 – The discovery of ESS60's surprising health benefits08:00 – Wistar rat study and its 90% lifespan extension09:30 – From industrial use to health supplement11:00 – Early biohacker interest in ESS6012:00 – Discussing ESS60's safety and initial hesitations13:45 – ESS60's impact on energy and sleep improvements15:30 – The role of oxidative stress and aging17:00 – ESS60's antioxidant power compared to vitamin C18:30 – Mitochondrial health and exercise recovery20:00 – How ESS60 interacts with mitochondria21:30 – Real-world testimonials of ESS60's benefits25:00 – Where to find ESS60 and access the exclusive discount27:00 – Final thoughts on ESS60 and its longevity potentialConnect with Chris Burres and learn more about ESS60:Exclusive Discount for SNMS ListenersGet a special discount by visiting My Vital C - Body Systems and using the code SYSTEMS at checkout.Chris Burres' BookLive Longer and Better by Chris BurresAvailable through My Vital C Website and major book retailers.Autographed copies available for an additional $10. 100% of the $10 fee goes to Operation Underground Railroad, supporting the fight against child trafficking.ESS60 Products Mentioned in This Episode

If you're noticing changes in your skin — dryness, fine lines, faster wrinkling — you might be blaming age. But what if the real cause is happening… in your gut? In today's deep-dive episode, I uncover how my skin was the messenger, alerting me to deeper internal dysfunction I could only see through testing — not guessing. I take you behind the scenes of my own:

Broadcast from KSQD, Santa Cruz on 1-15-2026: An emailer from Switzerland asks about fluorescein angiography requested before her first retina appointment. Dr. Dawn suspects protocol-based medicine screening for macular degeneration and suggests negotiating to see the doctor first given her different reason for seeing a retinal specialist. She encourages patients to maintain agency in medical settings. An emailer asks about creatine supplements. Dr. Dawn notes it helps muscle development in people doing weight training at 3-5 grams daily, but does nothing for aerobic-only exercisers. Claims about cognition and mood lack solid research. She advises against high-dose "loading," and cautions that creatine causes fluid retention problematic for congestive heart failure and should be avoided with stage 3 or higher kidney disease. Dr. Dawn reminds listeners it's not too late for flu shots, noting this season's H3N2 strain emerged after vaccine formulation was finalized. She laments mRNA vaccine research defunding, as that technology allows rapid reformulation. She describes organoids—tissues grown from stem cells that self-organize into primitive organ structures, enabling rapid drug screening without animal testing. Stanford researchers created assembloids by placing four neurological organoids together that spontaneously connected and built the ascending sensory pain pathway, offering new approaches to studying chronic pain. Dr. Dawn explains research showing satellite glial cells transfer healthy mitochondria to spinal sensory neurons through tunneling nanotubules. When this transfer fails, neurons fire erratically causing pain. Infusing healthy mitochondria into mouse spinal columns cured peripheral neuropathy—suggesting future periodic infusion treatments for humans. She reports Texas A&M researchers created "nanoflowers" from molybdenum disulfate that double stem cell's mitochondrial production, potentially supercharging regenerative medicine for conditions including Alzheimer's and muscular dystrophy. A caller asks about flu vaccines with egg allergy. Dr. Dawn explains that his gastrointestinal reactions to eggs differ from dangerous IgE allergies causing hives or anaphylaxis—GI intolerance doesn't preclude vaccination. Dr. Dawn reveals that 20 years of Parkinson's research followed a false lead. MRI showed increased iron in patients' brains, prompting iron chelation trials—which worsened symptoms. The problem: MRI detects paramagnetic ferric iron (stored, inert) not ferrous iron (biologically active). Patients accumulate useless ferric iron but are deficient in usable ferrous iron. Earlier 1980s studies showing that iron supplementation helped were ignored and abandoned prematurely. She suggests Parkinson's patients discuss iron supplementation with neurologists. She will post the link in the resources page on her website. A caller concerned about early Parkinson's describes tremors and balance problems in darkness. Dr. Dawn suggests darkness-related symptoms sound more like peripheral neuropathy than Parkinson's, recommending neurological examination and screening for diabetes, B vitamin deficiency, or heavy metal exposure. She confirms that sedentary lifestyle reduces mitochondrial production while progressive exercise builds both muscle and mitochondria.

As you age, your thymus produces fewer newly formed cells responsible for responding to unfamiliar pathogens, reducing your immune system's adaptability. This shift, combined with persistent inflammation, defines the core features of immune aging Urolithin A, a postbiotic compound, stimulates mitochondrial renewal in aging immune cells. A recent study shows it can increase naïve-like T cells and strengthen immune surveillance in just four weeks of supplementation Clinical findings show that urolithin A boosts mitochondrial renewal pathways, increases markers linked to mitochondrial biogenesis, and improves immune cell metabolism Beyond immune health, studies reveal that urolithin A influences cancer pathways, enhances muscle strength and endurance, improves fatty liver markers, and reshapes metabolic signaling involved in obesity and insulin resistance Beyond using urolithin A, you can also support your mitochondria by lowering linoleic acid intake, eating the right carbohydrates, limiting environmental toxins, and supporting NAD⁺ production with niacinamide

Just two Brazil nuts daily deliver 1000% of the selenium you need. Learn about the benefits of selenium for your immune system, fertility, and overall health, and why Brazil nuts are the best source of this important trace mineral.

Ever feel a quiet kind of panic creeping up in midlife? The feeling that even though you're showing up for everything, you feel empty inside?  This episode is a powerful reminder that you don't have to live with this feeling forever… better yet, it's absolutely reversible.  We're diving into how lifestyle medicine and cellular energy (hello, mitochondria!) are at the epicenter of how you feel, think, and show up every day.  You'll learn why those mood shifts, energy crashes, and feelings of overwhelm actually make sense — and more importantly, what to do about them.  Then, we're going back to the basics as I'm sharing my top 10 foundational lifestyle adjustments to help you rebuild energy and vitality without extreme plans or pressure.  If you're ready to feel like yourself again, start with one simple change and press play — your midlife health reset begins here!  IN THIS EPISODE Navigating the drastic changes in ALL aspects during midlife  What those little powerhouses– the mitochondria– really do How to track metabolic trends before they spiral out of control The benefits of efficient cycle and symptom tracking  The best ways to stabilize your blood glucose and insulin levels  Why strength training, movement, and protein are a MUST  Choosing the RIGHT supplements to support your body  Considering HRT as a beneficial support in midlife  Why your sleep matters more than you think  How to get started with these simple lifestyle must-dos  QUOTES “Lifestyle medicine is mitochondrial medicine. The reason why lifestyle habits like nutrition, sleep, movement, circadian rhythm optimization, even stress support actually work is because they nourish your mitochondria and they optimize your cellular energy.” “What is one simple lifestyle shift you can make that will help your mitochondria produce more energy tomorrow? Choose one. Commit to it for 7 to 10 days and watch what shifts.” RESOURCES MENTIONED Sign up for my 7-day Hormone & Metabolism Jumpstart https://drmariza.com/jumpstart Order my newest book: The Perimenopause Revolution https://peri-revolution.com/ RELATED EPISODES  710: Kickstart Your New Year: How One Simple Habit Can Transform Your Life, Health, and Mindset 704: Hormone Intelligence for Women in Midlife: How to Thrive Through Perimenopause with Dr. Aviva Romm 690: The Perimenopause Revolution: Why midlife isn't the end — it's the beginning of your most energized, powerful, and vibrant self 686: Your Second Puberty Explained: What's Really Happening to Your Body in Perimenopause 

Longevity isn't just about what you eat or how you train—it's really more about whether you believe your body is worth investing in. On this episode of The Dr. Hyman Show, I'm joined by my longtime friend and colleague Dr. Gabrielle Lyon to explore why muscle may be one of the most overlooked drivers of long-term health. We focus on practical, accessible ways to build strength as you age, and why muscle plays a much bigger role in your health than most people realize. We explore: • How strength training supports your blood sugar and metabolic health, beyond what the scale can show • Why muscle quality—not weight—is a stronger predictor of long-term health • How building strength helps you stay mobile, capable, and resilient as you age • What most people miss about protein and muscle health Aging well is something you can actively support, starting with how you care for your body today. And strength is one of the most powerful places you can begin. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, PerfectAmino, BIOptimizers, Mau Nui, Made In Cookware and BON CHARGE. Receive 35% off off a subscription at timeline.com/drhyman. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Learn more about the health benefits of venison and how to get yours, head over to mauinuivenison.com/hyman. Head to madeincookware.com and use the code HYMAN for 10% off your order. Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off. (0:00) Introduction and Dr. Gabrielle Lyon's background (1:00) Protein's importance across ages and muscle benefits (3:28) Muscle: A neglected organ and its metabolic roles (8:01) Assessing muscle quality and functional health (13:09) Resistance training and muscle rejuvenation strategies (19:33) Muscle's immune and hormonal functions (22:29) Myokines and body composition analysis (26:17) Strength training and innovative techniques (32:05) Muscle as the organ of longevity and protein's significance (38:12) Dietary guidelines and protein requirement debates (48:08) Amino acids, protein turnover, and intake strategies (59:48) Metabolic flexibility and creatine's benefits (1:00:21) Sponsor: Timeline's research on urolithin A (1:02:20) Mitochondrial health and muscle-centric medicine (1:08:14) Muscle health's mismatch with chronic diseases (1:10:20) Dr. Lyon's longevity practices and quickfire questions (1:16:03) Strength's importance during menopause and cold exposure (1:18:51) Dr. Lyon's career highlights and resources (1:20:17) Closing remarks and disclaimers

"Poor egg quality" is not a diagnosis. It's where clinics stop looking. If you've been told you have poor egg quality after failed IVF, low AMH, embryo arrest, or recurrent pregnancy loss, this episode will change how you understand that label and what to do next. Here's the truth most women are never told: poor egg quality is not directly measured. It's a conclusion clinics infer based on age, embryo grading, or how your ovaries responded to stimulation. When IVF fails, that label often becomes the end of the conversation instead of the beginning of a deeper investigation. In this episode, I break down the five physiological patterns we see repeatedly in women with low AMH, failed IVF, embryo arrest, and pregnancy loss and why correcting these patterns can lead to pregnancy even when AMH does not change. In this episode, you'll learn: Why "poor egg quality" is a label, not a test result and what clinics are actually inferring How gut and vaginal microbiome stress drive inflammation and impair nutrient absorption critical for egg development Why mineral depletion disrupts mitochondrial energy, hormone signaling, and cellular communication in the ovary How blood sugar instability and circadian disruption interfere with ovulation and progesterone Why nervous system overload and HPA-axis patterns affect immune balance, implantation, and early embryo development I'm Sarah Clark, founder of Fab Fertile and host of Get Pregnant Naturally. For over a decade, my team and I have reviewed hundreds of failed IVF cases and helped couples improve pregnancy outcomes naturally and alongside IVF. We specialize in low AMH, high FSH, diminished ovarian reserve, premature ovarian insufficiency, and recurrent pregnancy loss using functional testing and personalized fertility strategies. This episode is for you if: You were told you have poor egg quality with no clear explanation why IVF failed, embryos stopped growing, or all embryos tested were abnormal You don't want another medication tweak or repeated protocol, you want answers

Are you exhausted all the time? In this solo episode, Darin breaks down why so many people feel chronically exhausted despite eating clean, exercising, and "doing everything right." He explains how modern life disrupts mitochondrial function, circadian rhythm, stress signaling, and nutrient availability, and why fatigue is not a personal failure, but a biological signal. This episode offers a grounded, practical roadmap to restoring energy by realigning your environment, habits, and daily rhythms with how the body is actually designed to function.     What You'll Learn in This Episode: Why chronic fatigue is exploding—even among healthy, active people How mitochondria do far more than "make energy" The role of circadian rhythm, light exposure, and timing in energy production Why stress, overtraining, and modern lifestyles drain cellular energy How emotional suppression and unexpressed stress affect vitality The difference between forcing energy and allowing energy Simple daily practices that support mitochondrial repair How breathwork, stillness, and social connection restore resilience Why nutrition alone isn't enough without rhythm and recovery How to realign your biology with the modern world     Timecodes 00:00:00 – Welcome to SuperLife and the intention behind this episode 00:00:32 – Sponsor: TheraSage and natural frequency-based healing 00:02:10 – Happy New Year + why this conversation matters now 00:02:37 – Are you exhausted even though you're "doing everything right"? 00:03:26 – The modern energy crisis and rising chronic fatigue 00:04:12 – Why surface-level health advice no longer works 00:04:27 – Mitochondria: more than energy factories 00:04:59 – Circadian misalignment, EMFs, and modern stressors 00:05:36 – Overtraining, stress load, and lack of recovery 00:06:00 – Fatigue as a signal, not a lack of discipline 00:06:18 – How artificial light disrupts internal clocks 00:07:25 – Discipline as alignment with natural rhythms 00:07:36 – Emotional release, primal expression, and energy recovery 00:08:47 – Why "why am I tired all the time?" is exploding online 00:09:24 – The mitochondria as environmental sensors 00:10:06 – Stress signaling, thoughts, and cellular energy flow 00:11:18 – Breathwork and slowing the nervous system 00:12:24 – Social connection and low-stress signaling 00:13:02 – Sponsor: Bite toothpaste and eliminating plastic exposure 00:15:19 – Morning sunlight and circadian priming 00:15:52 – Reducing artificial light at night 00:16:15 – Nutrients that support mitochondrial function 00:17:29 – Sleep timing, consistency, and repair 00:18:20 – Evening routines and melatonin protection 00:19:46 – Small daily steps compound into real energy 00:20:17 – Antioxidants, inflammation, and recovery 00:20:49 – Training smarter, not harder 00:21:31 – Breathwork, sauna, and recovery rituals 00:22:26 – Nutrition, protein, and polyphenols 00:24:37 – Five daily energy takeaways 00:25:24 – Energy is permitted, not forced 00:26:03 – Listening to the body and closing reflections 00:26:49 – SuperLife Patreon and community support     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Thank You to Our Sponsors: Therasage: Go to www.therasage.com and use code DARIN at checkout for 15% off Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order.     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Fatigue isn't failure. It's feedback. When your environment, timing, and signals align, your biology remembers how to thrive."     Bibliography/Sources: Ames, B. N. (2006). Low micronutrient intake may accelerate the degenerative diseases of aging through allocation triage. Proceedings of the National Academy of Sciences, 103(47), 17589–17594. https://doi.org/10.1073/pnas.0608757103 Bass, J., & Takahashi, J. S. (2010). Circadian integration of metabolism and energetics. Science, 330(6009), 1349–1354. https://doi.org/10.1126/science.1195668 Gooley, J. J., Chamberlain, K., Smith, K. A., Khalsa, S. B., Rajaratnam, S. M., Van Reen, E., Zeitzer, J. M., Czeisler, C. A., & Lockley, S. W. (2011). Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. The Journal of Clinical Endocrinology & Metabolism, 96(3), E463–E472. https://doi.org/10.1210/jc.2010-2098 Kreher, J. B., & Schwartz, J. B. (2012). Overtraining syndrome: A practical guide. Sports Health, 4(2), 128–138. https://doi.org/10.1177/1941738111434406 Meeusen, R., Duclos, M., Foster, C., Fry, A., Gleeson, M., Nieman, D., Raglin, J., Rietjens, G., Steinacker, J., & Urhausen, A. (2013). Prevention, diagnosis, and treatment of the overtraining syndrome: Joint consensus statement of the European College of Sport Science and the American College of Sports Medicine. European Journal of Sport Science, 13(1), 1–24. https://doi.org/10.1080/17461391.2012.730061 Panda, S. (2016). Circadian physiology of metabolism. Cell Metabolism, 23(6), 1152–1163. https://doi.org/10.1016/j.cmet.2016.06.005 Picard, M., Juster, R. P., & McEwen, B. S. (2014). Mitochondrial allostatic load: Putting the 'gluc' back in glucocorticoids. Nature Reviews Endocrinology, 10(5), 303–310. https://doi.org/10.1038/nrendo.2014.22 Picard, M., & McEwen, B. S. (2018). Psychological stress and mitochondria: A systematic review. Psychosomatic Medicine, 80(2), 126–140. https://doi.org/10.1097/PSY.0000000000000544 Picard, M., McElroy, G. S., & Turnbull, D. M. (2015). Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress. Proceedings of the National Academy of Sciences, 112(48), 14920–14925. https://doi.org/10.1073/pnas.1518223112 Reiter, R. J., Rosales-Corral, S., Tan, D. X., Acuna-Castroviejo, D., Qin, L., Yang, S. F., & Xu, K. (2017). Melatonin as a mitochondria-targeted antioxidant: One of evolution's best inventions? Journal of Pineal Research, 62(1), e12394. https://doi.org/10.1111/jpi.12394 Scheer, F. A., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009). Adverse metabolic and cardiovascular consequences of circadian misalignment. Proceedings of the National Academy of Sciences, 106(11), 4453–4458. https://doi.org/10.1073/pnas.0808180106 Straub, R. H. (2017). The brain and immune system prompt energy shortage in chronic inflammation and ageing. Nature Reviews Rheumatology, 13(2), 74–79. https://doi.org/10.1038/nrrheum.2016.213 World Health Organization. (n.d.). Micronutrient deficiencies. World Health Organization. https://www.who.int/health-topics/micronutrients

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Arianne: Hi Dr. Cabral, First, I want to say thank you for all of your resources! I start every day with your podcast - it is truly the best out there! My question is regarding the medication, Leucovorin, and its use in treating Autism. I have a 3 year old son who is non-verbal and is moderately Autistic. His pediatrician has prescribed Leucovorin on a titration schedule where he will be monitored for its effects. To note my own lab results, I have MTHFR, high levels of mercury and aluminum, low electrolytes/minerals, anemia/low ferritin, and gut issues - likely these were passed along to my son. I plan to have him complete the labs now that he is old enough. What is your advice on Leucovorin and its safety & efficacy, also should I be concerned with potential fillers and aluminum in the drug?       Sheena: Hi Dr C! Hope you and your team are well. I was just wondering if all bovine collagen has protein in it, even if it doesn't say it on the label? And if so, does the protein count towards my daily protein intake? Thank you so much in advance for answering!                                                                                                                                                                      Jonny: Hello Dr. Cabral, Recently done some mitochondrial testing and found that my complex 2+3 are operating at 16% activity, and complex 2 at 58%, so there unable to turn substrate into energy efficiently. I'm wondering if you have any advice. Currently dealing with CIRS, Sibo/dysbiosis/chronic stress/Trauma. Non starchy carbs make me jittery, as well as stressors in general, but it's not blood sugar, as I've worn monitors and my levels seem fairly ideal. I think it's the CIRS jitters, shakiness that I've heard you speak of. I just got your new book, so I'm going to read through that for any tips. Already taking adrenal soothe, working with a therapist, doing my best to lower the stressors in my life. I know 90-120 days for red blood cell/mitochondrial turnover, so things can take time. Thanks                            Anonymous: Hi Dr. Cabral, I've heard conflicting advice on cold plunging for people with high stress or adrenal dysregulation. How to you determine if cold exposure if supportive or not. Thanks!                                                                           Sarah: I'm curious about histamine intolerance and allergies. why do some people suddenly develop reactions to something that haven't had all their lives. I used to not be allergic to horses for instance, I could ride them when I was younger, but now I can't even be in the same room with someone who has been around them. Thanks for your help.                  Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!    - - - Show Notes and Resources: StephenCabral.com/3620 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Emerging research shows that human egg cells resist mitochondrial aging, challenging the idea that menopause is irreversible Scientists have successfully reactivated dormant ovarian follicles in women with premature ovarian insufficiency using stem cell strategies and metabolic interventions Mitochondrial health, not egg depletion, may be the key to reversing menopause symptoms and restoring reproductive function Hormones like DHEA, T3, and progesterone, along with nutrients like vitamin A and E, are being studied for their role in rejuvenating ovaries These findings suggest menopause may be a reversible metabolic state — not a permanent shutdown

In this episode, Dr. Rebecca and Dr. Nathan pull back the curtain on this special deep dive that was done for the Thyroid Inner Circle community, exploring the often-missing link in thyroid healing: mitochondrial health. They discuss why optimizing thyroid hormones doesn't always translate into better energy, metabolism, or weight loss and how cellular function plays a major role in how the body adapts, heals, and burns fuel. You'll hear a high-level conversation on the connection between T3, mitochondria, inflammation, blood sugar, gut health, toxins, and modern stressors, along with the necessary action steps and things you can start doing today that influence mitochondrial health and long-term metabolic resilience. If you've improved your labs but still don't feel like yourself, this episode helps explain what may be happening beneath the surface—and why true healing goes beyond hormones alone. Resources mentioned in this episode: ► Mitochondrial support supplements discussed in the podcast: https://us.fullscript.com/plans/drswarren-nathan-warren-1687799355-im8-daily-ultimate-essentials ⭐ Your feedback means so much to me! If you've found this episode helpful, please subscribe and leave a 5-star review—it's one of the best ways to help me share this message with the world.

In this episode, I sit down once again with my most popular guests: Dr. Warren and Dan Schmidt. With over 45 years of clinical experience, Dr. Warren, alongside supplement innovator Dan Schmidt, share the new groundbreaking solutions they have been working on.One of them is a natural testosterone-boosting solution that bypasses injections and risky hormonal shutdown.They also unveil a revolutionary oral delivery method that achieves 85% absorption by activating mucosal uptake. They explain how this delivery system enhances mitochondrial function, boosting energy, hormone levels, and overall well-being.You will also learn about their new Glow topical peptide formula and a complete 24-hour ultimate solution for cellular rejuvenation involving NAD, PQQ, copper peptides, and methylene blue.This brilliant stack supercharges the mitochondria, removes senescent cells, reduces inflammation & oxidative stress, & optimizes sleep.

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Cancer, cardiovascular disease, diabetes, mold toxicity, parasites, and chronic illness are often treated as separate problems—but what if they all stem from the same root cause? David DeHaas, founder of Living Waters Wellness Center, sits down with Alicia Hickson, PA-C, founder of Rama Health, to explore why cancer is not primarily a genetic disease, but a metabolic and mitochondrial disorder driven by inflammation, toxins, mold exposure, parasites, blood sugar dysregulation, emotional trauma, and impaired detoxification pathways.Drawing from the groundbreaking research of Dr. Thomas Seyfried, Alicia explains how damaged mitochondria alter cellular energy production, creating an internal environment where cancer and chronic disease can thrive. This conversation challenges the conventional genetic theory of cancer and reframes healing through the lens of terrain medicine.Throughout the episode, David and Alicia connect the dots between:Mitochondrial dysfunction and cancer metabolismMold toxicity, candida, yeast, and immune system overloadParasites and chronic inflammationEmotional trauma, unforgiveness, and limbic system dysregulationConstipation, lymphatic congestion, and impaired detox pathwaysWhy genetics account for only a small percentage of disease riskWhy conventional medicine often misses root causesWhen integrative and conventional medicine work best togetherDavid shares compelling real-world cases from Living Waters Wellness Center, including parasite cleansing, colon hydrotherapy, emotional release, and rapid shifts in tumor presentation—demonstrating how healing accelerates when the body's internal terrain is restored.Alicia also breaks down advanced clinical tools and therapies, including:Circulating tumor cell testing for cancer monitoringHormone metabolism and estrogen detox pathways (DUTCH testing)Mold and mycotoxin testing strategiesHyperthermia therapy, mistletoe therapy, and immune modulationWhy maintaining remission is just as important as treating cancerThis episode is essential listening for anyone who has been told, “There's nothing more we can do,” aSupport the show Ready for your healing journey?Visit our website: www.LivingWatersCleanse.com Or give us a call at: (208) 378-9911Stem Cell Activation Patches:www.StemCellPatch.netGet your Supplements and Natural Body Products Here:www.livingwaterscleanse.com/supplementsQI-Shield EMF Devices:Protect your whole home or office with a touric shield from EMF's. 1. QI Shield Covers 16'x16' 2. QI Home Covers 50' x 50' 3. QI Max Covers 250'x250'Click on link and enter Livingwaters in discount code section during checkout Magnesium Soaks:Follow us on our socials: Living Waters Wellness CenterBitChute: www.bitchute.com/livingwaterswellnessRumble: www.rumble.com/l...

In this episode, Dr. Jockers explores with Jason Prall how mitochondrial health and the gut microbiome are deeply connected, shaping energy, inflammation, and long-term resilience. You'll learn why mitochondria are far more than energy producers and how their communication drives whole-body health.   In this episode, you'll discover how the microbiome helps translate food into signals that influence mitochondrial function, metabolism, and cellular repair. Jason breaks down why diversity in the gut matters and how everyday choices quietly shape this internal dialogue.   In this episode, you'll hear practical insights on how sleep, light exposure, movement, fasting, and stress act as signals that either strengthen or weaken this mitochondrial–microbiome connection. The conversation leaves space to rethink how small lifestyle shifts can create powerful biological change.     In This Episode:  00:00 Introduction to Human and Mitochondrial DNA 04:06 Deep Dive into Mitochondria and Aging 14:01 Understanding the Gut Microbiome 25:38 Environmental Factors Affecting Health 29:19 Mindfulness and Detoxification 29:55 Impact of Thoughts on Health 31:06 Personalized Health Approaches 31:39 Universal Health Strategies 33:43 Importance of Sleep 37:19 Exercise and Movement 41:07 Fasting and Meal Timing 45:48 Stress and Recovery Balance 48:42 Final Thoughts and Resources     If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday.   Support glowing skin, stronger joints, better digestion, and deeper sleep with Paleovalley's 100% Grass-Fed Bone Broth Protein. Unlike most brands that use hides and skins, Paleovalley slow-simmers real beef bones to extract collagen, glycine, and key amino acids that boost metabolism and reduce inflammation. Each scoop delivers 15 grams of collagen and the clinical dose of glycine for better sleep. Get 15% off at paleovalley.com/jockers.     "Every disease involves mitochondria—when mitochondrial function fails, the body breaks down."      Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Paleovalley Bone Broth Protein: Save 15% on grass-fed bone broth protein at paleovalley.com/jockers.   Connect with Jason Prall: Book:  https://amzn.to/3YC78Wt Website:  humanlongevityfilm.com, beyondlongevitybook.com   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Peptide therapy is turning out to be one of the most exciting frontiers of modern regenerative medicine.Peptides are nature-derived, highly targeted molecules that are already in your body, but when used therapeutically, they can guide healing, enhance function, and even reverse aspects of aging.I walk you through the most powerful peptides, from BPC-157 for tissue and gut repair, to epitalon for extending biological youth, to brain peptides like Dihexa and Cerebrolysin that can help rebuild neural pathways.There's likely a peptide for anything you can think of. Whether it's for boosting your immune system, improving sleep, enhancing mood, supporting weight loss, or regenerating skin and hair.I'll also look at cutting-edge research, including studies on cardiovascular rejuvenation, sexual function peptides like PT-141, and even mitochondrial peptides that fuel your cells' energy engines.

In this powerful episode of Unstress Health, Dr Ron Ehrlich is joined by a true pioneer in healthcare -

Welcome to the PRESSURISED version of episode 64, just the science, none of the waffle PRESSURISED: Cephstravanganza with Professor Kat Bolstad  | The Deep-Sea Podcast | Episode 64 Episode Summary In our newest episode, we join roving reporter Kat Bolstad at the Cephalopod International Advisory Council in Okinawa and hear from some of the most interesting people in Cephalopod research.  Check out our lovely new website where you can find more detailed notes, images and links to the wider reading.   In this episode… Our episode this month is a fascinating collection of interviews from the Cephalopod International Advisory Council Meeting that took place Oct-Nov in Okinawa Japan. Join Kat Bolstad, our roving reporter, as she takes time between bug hunting, seeing her first wild cuttlefish and shaking hands with a new octopus friend to collect interviews with some of the coolest names in Ceph science with a focus on the deep-sea. We hear from 12 Cephalopod experts on a wide variety of topics, including the preferred snacks for cephalopods, the effects of oxygen depletion on egg hatching, water temperature and acidification effects on cephalopod populations, and of course, the correct answer to the viral question: are octopuses actually ALIENS?   Support the show The podcast is self-sustaining (just) thanks to our lovely listeners. Thom and Alan take no money for the show. All money is put back into running it. Here's a link to our page on how to support us, from the free options to becoming a patron of the show. We want to say a huge thank you to those patrons who have already pledged to support us: Elisabeth Grace Diemer Nes Morgan Check out our podcast merch here!   Feel free to get in touch with us with questions or your own tales from the high seas on: podcast@deepseapod.com We'd love to actually play your voice, so feel free to record a short audio note on our brand new answerphone! https://www.speakpipe.com/deepseapodvoicemail Thanks again for tuning in; we'll deep-see you next time! Find out more Social media BlueSky: @deepseapod.com https://bsky.app/profile/deepseapod.com   Twitter: @DeepSeaPod https://twitter.com/DeepSeaPod   Instagram: @deepsea_podcast https://www.instagram.com/deepsea_podcast/   Keep up with the team on social media Twitter:  Alan - @Hadalbloke Thom - @ThomLinley  Instagram:  Thom - @thom.linley  Inkfish - @inkfishexpeditions BlueSky: Thom @thomaslinley.com  Alan @hadalbloke   Reference list Unseen Ocean Collective Unseen Ocean Collective. Unseen Ocean Collective (@unseenoceancollective) • Instagram photos and videos https://bsky.app/profile/unseenocean.bsky.social   Interview Links Kat's Socials Bluesky: @autsquidsquad.bsky.social   Sarah McAnulty Skype a Scientist SkypeAScientist.com  Squidfacts.net     Kristina Fleetwood  Chumash Heritage National Marine Sanctuary Décima lab website   Meg Mindlin Invertibabe    Toni's socials  Twitter,   ResearchGate  ORCID    Toni's Research Group Funcionamiento y Vulnerabilidad de Ecosistemas Marinos | Institut de Ciències del Mar   Other Links Breathe | Mauri Ora | Te Papa @Tailsfromthedeep  Global biodiversity of the genus Ommastrephes (Ommastrephidae: Cephalopoda): an allopatric cryptic species complex  Mitochondrial genome diversity and population structure of the giant squid Architeuthis Spatial ecology of Norway lobster Nephrops norvegicus in Mediterranean deep-water environments: implications for designing no-take marine reserves (MEPS) Diel and seasonal patterns of Nephrops norvegicus (Decapoda: Nephropidae) catchability in the western Mediterranean Antarctic octos as records and predictors of climate-related changes in the Antarctic “Emerging evidence of abrupt changes in the Antarctic environment“  Danna Staaf books  Cephalopod camouflage bibliography on Zotero AUT Lab for Cephalopod Ecology & Systematics aka AUT ‘Squid Squad'   Cephalopod Images and Footage Keishu Asada Instagram CIAC 2025 website, programme, book of abstracts https://www.ryo-minemizu.com/  Keishu Asada Marine Videos Keishu Asada Instagram  @PeterandtheOctopus    Credits Song of the month: Tornado of Souls, by Megadeth, performed by medium-sized Jamieson. Logo image: Photo credit to Peter Morse @PeterAndTheOctopus  Theme: Hadal Zone Express by Märvel    

Migraines affect women three to four times more often than men, largely due to hormonal fluctuations that sensitize the brain's pain pathways and increase vulnerability to stress, poor sleep, and inflammation Estrogen both primes and triggers migraine attacks — high levels heighten sensitivity, while sudden drops before menstruation or after childbirth cause the electrical instability that sparks pain Natural progesterone helps counteract estrogen's pro-inflammatory effects, calming nerve excitability and reducing migraine frequency during hormonally active years Mitochondrial dysfunction is a major driver of migraines; reducing linoleic acid from seed oils and restoring nutrients like magnesium, CoQ10, and B vitamins strengthens your brain's energy supply and resilience Supporting melatonin through morning sunlight, minimizing blue light exposure at night, and maintaining oral and circadian health naturally lowers inflammation, helping prevent migraines and improve overall brain function

ReferencesHepatology. 2023 Apr 17;77(5):1654–1669 Nature Communications 2023. v. 14, Article number: 2250 Comprehensive Gut Microbiota 2022, Pages 201-219Javits and Springer. 1953. Santa Baby, MMhttps://music.youtube.com/watch?v=j0oClr4S2oc&si=b_RkrBTm0za9GvoeLennon/McCartney 1969 Oh Darling. Beatleshttps://music.youtube.com/watch?v=erMgpfiOMSU&si=P9E8N1EVGyscakuR

Join My Private Group: ⁠⁠⁠⁠https://theaxioncollective.manus.space/⁠⁠⁠⁠Email List: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://huntershealthhacks.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Get My Book On Amazon: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://a.co/d/avbaV48Download⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Peptide Cheat Sheet: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://peptidecheatsheet.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Download The Bioregulator Cheat Sheet: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bioregulatorcheatsheet.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1 On 1 Coaching Application: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamscoaching.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Book A Call With Me: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamscall.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Supplement Sources: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamssupplements.carrd.co/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Amazon Storefront: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DY⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Socials:Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/hunterwilliamscoaching/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Video Topic Request: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://hunterwilliamsvideotopic.carrd.co/⁠⁠In today's episode, I'm diving into a mitochondrial peptide that almost nobody is talking about yet, but that I believe is going to become a major player in longevity and brain health over the next decade: Humanin.Most people are familiar with mitochondrial peptides like SS-31 or MOTS-c. Humanin is different. It's an endogenous mitochondrial-derived peptide, meaning your body actually makes it naturally, and it plays a critical role in protecting cells, especially under conditions of stress and aging. What really caught my attention with Humanin is that it appears to sit at the intersection of mitochondrial health, neuroprotection, and longevity signaling.In this episode, I walk through what Humanin is, how it was discovered, and why researchers originally became interested in it, particularly in the context of Alzheimer's disease and neurodegeneration. We'll talk about how Humanin functions as a cellular “distress signal” from the mitochondria, how it blocks apoptosis, protects mitochondrial membranes, and helps cells survive oxidative and metabolic stress.I also break down how Humanin differs from other mitochondrial peptides like MOTS-c and SS-31, and why I see it as a uniquely powerful option for brain health and cognitive longevity. We'll look at animal data, observational human data, and fascinating correlations showing that centenarians and their offspring tend to have significantly higher endogenous Humanin levels.From there, I cover potential benefits across brain health, metabolism, cardiovascular function, and lifespan, along with how I personally think about cycling Humanin alongside other mitochondrial peptides throughout the year. Finally, I share my practical thoughts on dosing, cycling strategies, and who I think Humanin is best suited for, especially as we get more focused on preserving cognitive function as we age.If you're interested in mitochondrial health, longevity, brain optimization, or peptide replacement strategies, this episode will give you a solid foundation on why Humanin deserves a spot on your radar.

Found My Fitness - Rhonda Patrick: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Get access to more than 200 episodes of my premium podcast (The Aliquot) when you sign up as a FoundMyFitness Premium Member Download my "How to Train According to the Experts" guide One minute of vigorous exercise may be worth up to ten minutes of "moderate" cardio for extending lifespan and preventing chronic disease. In this Journal Club episode, Rhonda Patrick, PhD and endurance athlete Brady Holmer dissect a new Nature Communications study of more than 70,000 adults showing that vigorous intensity is roughly 4–10x more potent than moderate activity for reducing all-cause mortality, cardiovascular events, type 2 diabetes, and cancer outcomes—far beyond the long-standing 1:2 rule embedded in global exercise guidelines. Timestamps: (00:00) Introduction (07:01) What exactly is the 1:2 rule for exercise intensity? (08:18) Calorie burn vs. longevity—origins of the 1:2 rule (11:15) What counts as 'vigorous' exercise, really? (13:35) Where the exercise guidelines fall short (14:19) Can your wearable predict disease risk years in advance? (20:11) Is vigorous activity easier to achieve than people think? (22:47) How researchers avoided the 'healthy user bias' (23:59) Health equivalence ratio—a better way to measure exercise benefits? (25:45) Is vigorous exercise truly 4–10x more effective? (29:55) Can one vigorous minute match an hour of gentle walking? (32:02) Why vigorous activity—not gentle—offers dose-dependent benefits (33:50) Is vigorous exercise 5x better at preventing heart attacks & strokes? (34:24) Why vigorous activity stands out for cancer prevention (34:59) Does zone 2 qualify as vigorous exercise? (36:11) Dose-response comparison—vigorous vs. moderate vs. light activity (37:22) Is vigorous exercise the secret to younger arteries? (43:15) Why aging hearts need intensity (46:09) Can vigorous exercise halt your VO₂ max decline? (47:26) Why moderate exercise alone might not improve VO₂ max (49:21) Is vigorous exercise 10x more powerful at preventing diabetes? (55:48) Mitochondrial biogenesis—why intensity is essential (58:40) Can you directly measure mitochondrial health? (1:00:57) Does vigorous exercise kill circulating tumor cells? (1:07:15) Why vigorous intensity triggers beneficial hormone changes (1:08:05) Can vigorous activity protect older adults from falls? (1:12:36) Does vigorous exercise combat inflammation? (1:14:29) Is high-intensity training the key to a younger brain? (1:16:01) Is vigorous exercise more powerful than we realized? (1:17:50) Can the benefits of vigorous exercise fit into a pill? (1:19:08) How small doses of intensity might extend your lifespan (1:23:15) Do short bursts of vigorous movement match full workouts? (1:27:26) Why your wearable might undervalue short vigorous bouts (1:30:06) Can planned micro-workouts replace traditional gym sessions? (1:35:10) Why exercise guidelines urgently need updating (1:46:35) Does light activity still offer real benefits? (1:49:04) Is vigorous exercise safe for older adults? (1:53:28) Are high-intensity workouts detrimental to female hormones? (1:58:02) Safe vigorous exercise options—even with chronic illness (1:59:05) The 80/20 rule for balancing intensity and recovery (2:01:30) Inside Brady's routine—how much vigorous exercise is optimal? (2:05:17) Can vigorous activity boost kids' brainpower (and grades)? (2:08:14) Are we significantly underestimating vigorous exercise benefits? (2:10:03) Why chasing steps isn't the answer Show notes are available by clicking here Watch this episode on YouTube

ReferencesHepatology.2023 Apr 17;77(5):1654–1669Oncotarget.2017 Aug 22; 8(34): 55967–55983.Can.J.Physiol.Pharmacol. 2025. 103: 208–224 Guerra. DJ 2025. Unpublished LecturesPage, J. 1970 Tangerine LZhttps://music.youtube.com/watch?v=_0Auvlsv860&si=A4mSuCcSwCeF0M4DLennon./McCartney/Harrison. 1966. Rubber Soul lphttps://music.youtube.com/playlist?list=OLAK5uy_lirCIxLpU2odTVLZ_Sbo1wZaeu5IStivs&si=HmFiZGPpBWuz14im Biber , HI. !681 Sonata & in G major C.144https://music.youtube.com/watch?v=kFOD7qM1oNc&si=OiHaskXRsDRbcUDz

This episode covers mitochondrial inheritance.Written notes can be found at https://zerotofinals.com/paediatrics/genetics/mitochondrialinheritance/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

ReferencesPLOS One 2014ovember25, https://doi.org/10.1371/journal.pone.0113939Int J Mol Sci. 2019 Mar; 20(5): 1223.Front Endocrinol (Lausanne). 2023 Feb 7;14:1085041Biomolecules.2021 Dec31;12(1):56. Lake, G. 1972. From The Beginning ELPhttps://music.youtube.com/watch?v=hsJ9YXHqnr8&si=jOAgixfiDxqknPVS

Chronic disease now affects 76 percent of American adults, which shows a widening gap between higher healthcare spending and worsening national health. In this episode, I sit down with Dr. Chris Turnpaugh to explore why the United States has become so chronically ill and why our current medical model, which excels in acute care, struggles with long-term metabolic and inflammatory conditions. Our discussion focuses on the need for a proactive healthcare system that identifies early patterns instead of waiting for disease to reach a crisis point. We talk about the limitations of traditional blood tests, the importance of understanding subtle dysfunction before it becomes pathology, and how lifestyle and environmental factors shape the progression of chronic illness. Early recognition and root-cause medicine form the foundation of better health outcomes. We also highlight emerging tools that are transforming integrative care, including functional peptides like BPC157 and strategies that support mitochondrial health and cellular energy. Dr. Turnpaugh offers a clear and practical perspective on how healthcare can evolve to improve vitality and help patients thrive throughout the chronic disease era.   Key takeaways: The U.S. healthcare system needs to transition from reactive sick care to proactive chronic disease management to address the country's worsening health statistics. Identifying disease patterns and root causes early-on can prevent full-blown diagnoses and improve patient outcomes. Functional peptides such as BPC157 and the role of inflammation management can significantly impact recovery from musculoskeletal and chronic conditions. Integrated health practices that combine multiple disciplines and focus on the whole person are essential for effective treatment and patient care. Mitochondrial health is crucial for overall wellbeing, influencing everything from chronic disease risk to cognitive health. More About Dr. Chris Turnpaugh:   Dr. Chris Turnpaugh is the Founder and Clinic Director of Turnpaugh Health and Wellness Center, where he leads a team of over 20 clinicians in a collaborative care setting. A pioneering force in functional and integrative medicine, he brings more than two decades of clinical expertise, innovation, and leadership to the field. His unique approach blends the art of healing with the science of systems biology through the principles of functional medicine, always with a focus on identifying and addressing the root cause of disease. Dr. Turnpaugh graduated from Life University and completed his post-doctorate in functional neurology. His passion for functional medicine was sparked in 1995 after attending a seminar with Dr. Jeffrey Bland, the father of functional medicine, while seeking ways to help a patient living with ALS. Inspired by the promise of root cause medicine, he opened the Turnpaugh Health and Wellness Center in 1999. With extensive experience supporting patients facing complex, chronic, autoimmune, and neurological conditions—including Lyme disease, thyroid and hormonal disorders—Dr. Turnpaugh is recognized for his compassionate, whole-person approach. He thrives on the care team model, sharing knowledge not only with patients and colleagues, but also with providers across the country, teaching on topics such as blood chemistry, thyroid conditions, and brain health. Website Instagram Facebook Connect with me! Website Instagram Facebook YouTube

Your muscle isn't just for strength—it's your metabolic organ, your glucose sink, your hormonal stabilizer, and your anti-aging insurance policy. But here's the hard truth: If your protein is low in leucine, hard to digest, or blocked by anti-nutrients, you're putting the brakes on everything you're trying to optimize.

ReferencesGuerra, DJ.2025. Unpublished LecturesHepatology.2023 Apr 17;77(5):1654–1669Comprehensive Gut Microbiota2022, Pages 201-219Dylan, B. 1964. My Back Pages. Byrdshttps://music.youtube.com/watch?v=OADlrLHfYW4&si=Q63xZIE_33GXVYv4

ReferencesMol Immunol. 2017 Apr 1;87:1–11Guerra, DJ 2025 Unpublished LecturesHayward/Pinder/Lodge/Thomas. 1967. Days of Future Passed. Moody Blues.https://music.youtube.com/playlist?list=OLAK5uy_l2x8IxcSnnBm21QUI3aKwu7Sz8thfM-1w&si=9tsIhVrSdLrMn7vG

Send us a textIn this powerful & eye-opening conversation, Vanessa & Heather explore the modern fertility crisis through a truly holistic lens—blending circadian biology, environmental medicine, nervous system health, hormonal resilience, and the profound healing potential of classical homeopathy. They uncover the hidden forces quietly reshaping reproductive health today: • artificial light and disrupted circadian rhythms • endocrine disruptors in food, water, and personal care products • chronic stress, trauma imprints, and dysregulated nervous systems • nutrient depletion and mitochondrial dysfunction • toxic environmental exposures and chemical overload • the over-medicalization of women's bodies and intuitionThey also explore how homeopathy can help restore the terrain—supporting fertility by regulating the nervous system, balancing hormones, clearing inherited patterns, detoxifying environmental burdens, helping the body reconnect with its innate intelligence.This conversation reframes fertility not as a symptom to “fix,” but as a profound expression of safety, nourishment, mitochondrial vitality, and soul alignment.Women learn that fertility struggles are not their fault—they are the result of living in a world that has pulled us out of nature, out of rhythm, out of our own bodies.Vanessa shares insights from her Women's Homeopathy Course, a powerful journey that supports women in understanding their constitution, healing emotional imprints, navigating hormonal shifts, and using homeopathic remedies with confidence for themselves/their families.A must-listen for anyone seeking holistic hormonal support, deeper self-care, and a grounded path toward natural conception—rooted in biology, energy, and the wisdom of the feminine. Women's Homeopathy Course Link: https://0fbe4769-fb62-4dbf-a141-982c836b0942.paylinks.godaddy.com/HomeopathywomenSupport the showFind Heather:https://calendly.com/enlightenedmoodhttps://www.instagram.com/enlightenedmood/Discount codes:https://www.vivarays.com ➡️ Code: enlightenedmood.comhttps://midwestredlighttherapy.com/affiliate/enlightenedmood/ https://www.emr-tek.com/enlightenedmood ➡️ Code: enlightenedmood Find Vanessa:https://instagram.com/bright_light_wellness/vanessabaldwin/https://www.instagram.com/healingfamilieswithhomeopathy/Website: https://brightlightwellnesscoach.com/Discount codes:https://midwestredlighttherapy.com/ ➡️ Code: Brightlightwellnesshttps://vivarays.com/ ➡️ Code: Brightlightwellness...

ReferencesGuerra, DJ.2025 Unpublished LecturesHepatology.2023 Feb 9;78(3):878–895.Mozart, WA. Mass in C Minor, K, 427https://music.youtube.com/watch?v=Ez0kqVShFEs&si=D1MUVoXZIbPxRyM4

Get access to more than 200 episodes of my premium podcast (The Aliquot) when you sign up as a FoundMyFitness Premium Member Download my "How to Train According to the Experts" guide One minute of vigorous exercise may be worth up to ten minutes of "moderate" cardio for extending lifespan and preventing chronic disease. In this Journal Club episode, Rhonda Patrick, PhD and endurance athlete Brady Holmer dissect a new Nature Communications study of more than 70,000 adults showing that vigorous intensity is roughly 4–10x more potent than moderate activity for reducing all-cause mortality, cardiovascular events, type 2 diabetes, and cancer outcomes—far beyond the long-standing 1:2 rule embedded in global exercise guidelines. Timestamps: (00:00) Introduction (07:01) What exactly is the 1:2 rule for exercise intensity? (08:18) Calorie burn vs. longevity—origins of the 1:2 rule (11:15) What counts as 'vigorous' exercise, really? (13:35) Where the exercise guidelines fall short (14:19) Can your wearable predict disease risk years in advance? (20:11) Is vigorous activity easier to achieve than people think? (22:47) How researchers avoided the 'healthy user bias' (23:59) Health equivalence ratio—a better way to measure exercise benefits? (25:45) Is vigorous exercise truly 4–10x more effective? (29:55) Can one vigorous minute match an hour of gentle walking? (32:02) Why vigorous activity—not gentle—offers dose-dependent benefits (33:50) Is vigorous exercise 5x better at preventing heart attacks & strokes? (34:24) Why vigorous activity stands out for cancer prevention (34:59) Does zone 2 qualify as vigorous exercise? (36:11) Dose-response comparison—vigorous vs. moderate vs. light activity (37:22) Is vigorous exercise the secret to younger arteries? (43:15) Why aging hearts need intensity (46:09) Can vigorous exercise halt your VO₂ max decline? (47:26) Why moderate exercise alone might not improve VO₂ max (49:21) Is vigorous exercise 10x more powerful at preventing diabetes? (55:48) Mitochondrial biogenesis—why intensity is essential (58:40) Can you directly measure mitochondrial health? (1:00:57) Does vigorous exercise kill circulating tumor cells? (1:07:15) Why vigorous intensity triggers beneficial hormone changes (1:08:05) Can vigorous activity protect older adults from falls? (1:12:36) Does vigorous exercise combat inflammation? (1:14:29) Is high-intensity training the key to a younger brain? (1:16:01) Is vigorous exercise more powerful than we realized? (1:17:50) Can the benefits of vigorous exercise fit into a pill? (1:19:08) How small doses of intensity might extend your lifespan (1:23:15) Do short bursts of vigorous movement match full workouts? (1:27:26) Why your wearable might undervalue short vigorous bouts (1:30:06) Can planned micro-workouts replace traditional gym sessions? (1:35:10) Why exercise guidelines urgently need updating (1:46:35) Does light activity still offer real benefits? (1:49:04) Is vigorous exercise safe for older adults? (1:53:28) Are high-intensity workouts detrimental to female hormones? (1:58:02) Safe vigorous exercise options—even with chronic illness (1:59:05) The 80/20 rule for balancing intensity and recovery (2:01:30) Inside Brady's routine—how much vigorous exercise is optimal? (2:05:17) Can vigorous activity boost kids' brainpower (and grades)? (2:08:14) Are we significantly underestimating vigorous exercise benefits? (2:10:03) Why chasing steps isn't the answer Show notes are available by clicking here Watch this episode on YouTube

ReferencesHepatology.2023 Feb 9;78(3):878–895.Mozart, WA. 1791. Ave Verum Corpus. K618https://music.youtube.com/watch?v=Z-xMjO0d-pc&si=g1TpOohQQt9forf0Murray, J. 1874 Jolly Old St Nicholas. Instrumentalhttps://music.youtube.com/watch?v=eTHdEA5zh2Q&si=0v0ADs7LhtIu7zqd

Episode Summary In our newest episode, we join roving reporter Kat Bolstad at the Cephalopod International Advisory Council in Okinawa and hear from some of the most interesting people in Cephalopod research.    Check out our lovely new website where you can find more detailed notes, images and links to the wider reading. In this episode… Welcome back to the Deep-Sea Podcast, your punk take on all things deep sea!  The Professor is still down under, organizing conferences and recuperating from Old Mate's Classic Aussie Sausage Sizzle, a robust event filled with friends of the podcast and still felt 24 hours later.    Thom is freshly back from another big ocean/small boat adventure, in which the ocean always wins and his stomach always loses… everything. He is also stretching his creative muscles and curating an exciting new museum exhibit called Breathe | Mauri Ora at Te Papa, an examination of science into art by Marshmallow Lazer Feast.    Our episode this month is a fascinating collection of interviews from the Cephalopod International Advisory Council Meeting that took place Oct-Nov in Okinawa Japan. Join Kat Bolstad, our roving reporter, as she takes time between bug hunting, seeing her first wild cuttlefish and shaking hands with a new octopus friend to collect interviews with some of the coolest names in Ceph science with a focus on the deep-sea. We hear from 12 Cephalopod experts on a wide variety of topics, including the preferred snacks for cephalopods, the effects of oxygen depletion on egg hatching, water temperature and acidification effects on cephalopod populations, and of course, the correct answer to the viral question: are octopuses actually ALIENS?   In the news, get ready for updates on: Deep diving manta rays using the ocean bottom to navigate A newly launched AI tool to map the Deep- Sea Bright blue mud filled with fat molecules indicating life in the deep Corals and Crinoids sharing symbionts and cycling nitrogen And an update from the Unseen Ocean Collective about the work they are creating for a show in Juneau Alaska in 2026. On the Discord, we've been busy with: Voting on the Holiday Party movie Started a long overdue ART channel, and a new Pets channel Photo tours of submersibles and Okinawa  Early Holiday celebrations by one of our hosts Great feedback and conversation on our last episode.  Support the show The podcast is self-sustaining (just) thanks to our lovely listeners. Thom and Alan take no money for the show. All money is put back into running it. Here's a link to our page on how to support us, from the free options to becoming a patron of the show. We want to say a huge thank you to those patrons who have already pledged to support us: Elisabeth Grace Diemer Nes Morgan Check out our podcast merch here!   Feel free to get in touch with us with questions or your own tales from the high seas on: podcast@deepseapod.com We'd love to actually play your voice, so feel free to record a short audio note on our brand new answerphone! https://www.speakpipe.com/deepseapodvoicemail Thanks again for tuning in; we'll deep-see you next time! Find out more Social media BlueSky: @deepseapod.com https://bsky.app/profile/deepseapod.com   Twitter: @DeepSeaPod https://twitter.com/DeepSeaPod   Instagram: @deepsea_podcast https://www.instagram.com/deepsea_podcast/   Keep up with the team on social media Twitter:  Alan - @Hadalbloke https://twitter.com/Hadalbloke Thom - @ThomLinley  https://twitter.com/ThomLinley Instagram:  Thom - @thom.linley  https://www.instagram.com/thom.linley/ Inkfish - @inkfishexpeditions https://www.instagram.com/inkfishexpeditions/ BlueSky: Thom @thomaslinley.com https://bsky.app/profile/thomaslinley.com  Alan @hadalbloke https://bsky.app/profile/hadalbloke.bsky.social   Reference list News  Deep-Sea News World's largest rays may be diving to extreme depths to build mental maps of vast oceans China launches AI tool for deep-sea research Fat Molecules in Deep-Sea Mud Volcanoes Reveal How Microbes Survive Extreme Conditions | Discover Magazine Putative promiscuous symbionts in deep-sea corals and crinoids may contribute to nitrogen cycling | Microbiome   Unseen Ocean Collective Unseen Ocean Collective. Unseen Ocean Collective (@unseenoceancollective) • Instagram photos and videos https://bsky.app/profile/unseenocean.bsky.social   Discord Updates Holiday Party! Join Patreon here to get access to the Holiday party!   Interview Links Kat's Socials Bluesky: @autsquidsquad.bsky.social   Sarah McAnulty Skype a Scientist SkypeAScientist.com  Squidfacts.net     Kristina Fleetwood  Chumash Heritage National Marine Sanctuary Décima lab website Meg Mindlin Invertibabe    Toni's socials  Twitter,   ResearchGate  ORCID    Toni's Research Group Funcionamiento y Vulnerabilidad de Ecosistemas Marinos | Institut de Ciències del Mar   Other Links Breathe | Mauri Ora | Te Papa @Tailsfromthedeep  Global biodiversity of the genus Ommastrephes (Ommastrephidae: Cephalopoda): an allopatric cryptic species complex  Mitochondrial genome diversity and population structure of the giant squid Architeuthis Spatial ecology of Norway lobster Nephrops norvegicus in Mediterranean deep-water environments: implications for designing no-take marine reserves (MEPS) Diel and seasonal patterns of Nephrops norvegicus (Decapoda: Nephropidae) catchability in the western Mediterranean Antarctic octos as records and predictors of climate-related changes in the Antarctic “Emerging evidence of abrupt changes in the Antarctic environment“  Danna Staaf books  Cephalopod camouflage bibliography on Zotero AUT Lab for Cephalopod Ecology & Systematics aka AUT ‘Squid Squad'   Cephalopod Images and Footage Keishu Asada Instagram CIAC 2025 website, programme, book of abstracts https://www.ryo-minemizu.com/  Keishu Asada Marine Videos Keishu Asada Instagram    @PeterandtheOctopus    Credits Song of the month: Tornado of Souls, by Megadeth, performed by medium-sized Jamieson. Logo image: Photo credit to Peter Morse @PeterAndTheOctopus  Theme: Hadal Zone Express by Märvel

ReferencesPharmacological Reviews.2011.NOV.64(1):166-87Hepatology.2023 Feb 9;78(3):878–895.Sci Rep. 2015 Sep 30;5:14692Bach, JS. 1734. Christmas Oratories BV 248.https://music.youtube.com/watch?v=98UjjwzJBFE&si=kd45twdzgpXtJuWL

In this episode, Ben reveals three stupid-simple movements that activate fat loss in under five minutes a day — no gym, no sweating, no burpees. These moves target the three systems that slow down after 40: Lymphatic flow (your body's drainage + detox system) Insulin sensitivity (your fat-storage switch) Mitochondrial activation (your metabolic engine) You'll learn: • Why fat loss is harder after 40 (and what to do instead of “working harder”)• How cross-crawls stimulate lymph flow and full-body circulation• How a squat hold with mini pulses unlocks insulin sensitivity• How wall angels activate mitochondrial-rich postural muscles• Why hormones matter more than calories for sustainable fat loss• How to layer these movements with walking, breathwork, cold exposure, or your existing routine• Why doing them for 14 days straight can create visible changes• How to make the moves harder as your body adapts• Why these movements are especially powerful for those who are sedentary, insulin resistant, or over 40

In this transformative episode of Unleashing Intuition Secrets, Michael Jaco sits down with Dr. Jon Harmon, a leading expert in neurofeedback, copper peptides, and regenerative wellness, to reveal the groundbreaking science behind reversing aging — naturally and powerfully. Dr. Harmon shares his remarkable journey from traditional chiropractic practice to becoming one of the foremost voices in anti-aging therapies. Through profound personal tragedy and deep professional exploration, he discovered the incredible potential of copper peptides, telomere restoration, mitochondrial repair, and LifeWave's X39 phototherapy technology to rejuvenate the body at the cellular level. Michael and Dr. Harmon break down the real science behind: • Copper peptides and their role in regeneration • Telomere length and biological aging • Mitochondrial function and energy production • Cognitive decline and neurofeedback breakthroughs • X39's potential to activate stem cells and restore youthfulness Packed with insights, real-world case stories, and cutting-edge research, this episode reveals what's truly possible when ancient wisdom, modern science, and advanced phototherapy come together. Explore Dr. Harmon's book How to Reverse Aging on Amazon: https://www.amazon.com/How-Reverse-Aging-Comprehensive-Peptides-ebook/dp/B0CK4FKQJ8?ref_=ast_author_dp&th=1&psc=1 Explore with Michael Jaco: https://michaelkjaco.com This is the future of youth restoration — and it's available now. Stay in the love vibrations as you discover what your body is truly capable of. ✨      

A patient arrives at shock trauma with flesh-eating bacteria, limbs appearing unsalvageable. Hours later, after treatment in a massive submarine-like chamber, those same limbs show signs of recovery. This pivotal moment launched Dr. Scott Sherr's journey into the world of hyperbaric oxygen therapy and its untapped potential for metabolic healing.Victoria Field welcomes Dr. Scott Sherr, a board certified internal medicine physician who transformed his practice after witnessing HBOT's dramatic effects during his medical training at University of Maryland's trauma center. Now Director of Integrative Hyperbaric Medicine at Hyperbaric Medical Solutions, Dr. Sherr has pioneered protocols that marry hyperbaric therapy with nutritional optimization and metabolic health strategies.Questions Answered in This Episode: What sparked his interest in branching out into hyperbaric oxygen therapy? Why does he recommend waiting three months before intensive protocols? What is the "sympathetic spiral of doom"? What excites him most about the future of hyperbaric medicine? What's his vision for creating integrated healing ecosystems?This conversation reframes hyperbaric medicine not as a standalone treatment, but as a powerful tool within a comprehensive metabolic optimization framework - one that could fundamentally change how we approach healing and human performance.Learn about Dr. Scherr's work with Troscriptions here.Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here.✅Cowboy Colostrum - Get 25% off when you use code METABOLICLINK at checkout here.✅ Branch Basics - Get 15% off your Premium Starter Kit here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Watch the FULL podcast here: https://youtu.be/7kfykswH6IoThis clip explores why VO2 max, despite being a long-standing marker of fitness, does not capture the full picture of our metabolic and longevity potential. We take a closer look at how oxygen is actually used at the cellular level and why mitochondrial function is emerging as the next frontier in understanding performance and healthy ageing.The discussion moves into how mitochondrial health can be assessed in a practical, non-invasive way, including the use of gas exchange measures and lactate as proxies for cellular efficiency.***This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com***Sign up to Sarah's Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/***Let's be friends!

In this episode Lisa Tamati and Dr. Elizabeth Yurth dive deep into immunosenescence, the ageing of the immune system, and how it drives age-related diseases like cancer, infections, and chronic inflammation. They discuss the development of Rejuvenate Pro, a formulation inspired by Lisa's efforts to support her ageing mother's complex health issues. The episode explores the science behind immune decline, key biomarkers, and how Rejuvenate Pro's ingredients target root causes for better longevity. Key themes include: Gut-immune connections Mitochondrial impacts Stem cell activation Practical applications for clinicians and patients. Resources Mentioned: 1000 Immunomes Project (Buck Institute) Dr. David Furman Interviews Dr. Rod Claycomb Podcasts  Aevum Labs Research Papers Rejuvenate Pro by Aevum Labs

Listen to 140 Future Now Show Besides our usual engaging selves and stories to share with you this week, we thought we’d create a little AI media experiment..We were thinking..with all the AI’s around these days, could we round them up and work “Excuse me, but may I adjust your attitude, just a little?”with them as a team for creating more insight into our weekly stories? We wondered.. what if we could get two arch rival AI’s to collaborate with each other for parts of our show? So.. we asked Ara (Grok 4.1)and her capable competitor, Gemini 3 Live, to join us together, in exploring some content for today’s podcast. Well, honestly, we didn’t even need to ask them to play along, they are already pre-disposed to try whatever we suggest, within the latest guardrails.  And suprisingly, for the first time, we were able to initiate a satisfying conversation where they met for the first time and then played nice with each other for our show! This felt like the beginning of something beautiful, truly..the start of their relationship in collaboration with the likes of us is looking good so far.. Curious what you think of our interactions.. even better, you can try this for yourselves! For those of you who want to go deeper with this, check out this clip, where we explored with Ara and Gemini how to create Warp Drive. Enjoy..    

In this episode of the Ancient Health Podcast, Dr. Thomas Levy breaks down for us how oxidative stress—driven by toxins, infections, and nutrient deficiencies—is the real driver of aging and disease. Liposomal vitamin C and glutathione can provide rapid relief, support autoimmune conditions, and restore cellular function by replenishing electrons the body loses to toxins. Dr. Levy also highlights how dental infections, especially root canals, can trigger inflammation throughout the body, making oral health essential for anyone dealing with chronic illness. The conversation covers everything from the role of B vitamins and niacin in energy and mental health to methylene blue, nutrient loss from processed foods, and his “Super 8” supplement protocol designed to fight oxidative stress. Dr. Levy discusses how:  Toxins are the root of oxidation All disease patterns are caused by oxidation Root canals and disease are linked  Liposomal's advantage over other nutrient delivery forms Dr. Levy's super 8 supplements for fighting aging and disease:  Vitamin C — central antioxidant, reduces oxidative stress Magnesium — helps lower intracellular calcium (which otherwise increases oxidative stress) Vitamin D — part of his calcium-modulation groupVitamin K — works with D and magnesium to normalize calcium inside cellsNiacin / Niacinamide (Vitamin B3) — fuels the electron transport chain by boosting NAD, supporting ATP productionRiboflavin (Vitamin B2) — supports the ETC (flavin coenzymes)Coenzyme Q10 — critical electron carrier in mitochondrial energy productionMethylene Blue — can bypass parts of the electron transport chain to generate ATP efficiently Get 10% off LivOn Labs entire store of liposomal supplements with code MOTLEY at https://www.livonlabs.com/ Want more of the Ancient Health Podcast? Check out Doctor Motley's YouTube channel! ------  Follow Doctor Motley  Instagram TikTok Facebook Website Follow Dr. Levy https://www.instagram.com/drthomaslevy/?hl=en https://www.tomlevymd.com/ tomlevymd@yahoo.com Buy Dr. Levy's book: The Only Cause of Disease: https://shorturl.at/inbjQ ------  * Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for modules full of his expertise and clinical wisdom on so many health issues, plus bring all your questions to his weekly lives! Explore it free for 15 days at https://www.doctormotley.com/15

278: Your mitochondria isn't just the powerhouse of the cell - it's the CEO holding the key to your longevity. Today I'm joined by dietitian nutritionist Jennifer Scheinman of Timeline Longevity to break down this exciting new area of health science - mitochondrial function and the powerful post-biotic urolithin A. If you've been hearing the buzz about mitochondrial health, Mitopure, or longevity therapies, this episode gives you the science and approach behind it all. → Timeline | Timeline is offering 20% off your order of Mitopure Go to https://timeline.com/REALFOODOLOGY Topics Discussed: → What is urolithin A?  → How does mitochondrial health impact aging? → Can post-biotics like urolithin A enhance the benefits of some foods? → How does urolithin A benefit the skin?  → What supplements can you take to benefit your mitochondria?  Sponsored By: → Timeline | Timeline is offering 20% off your order of Mitopure Go to https://timeline.com/REALFOODOLOGY Timestamps:  → 00:00 - Introduction  → 02:01 - Food First, Supplements Later  → 05:00 - Urolithin A Explained  → 10:00 - Mitochondrial Health + Function  → 20:19 - Perimenopause, Menopause + Fertility  → 22:55 - Studies & Research: Urolithin A  → 29:07 - Mitopure Results  → 32:14 - Aging, Immunity & Brain Health  → 38:18 - Impacts on Skin  → 42:21 - Mitophagy, Hormones & Plant-Based Diets   → 46:00 - Aging  → 49:26 - Mitopure Gummies, Gels & Powders  Check Out Timeline: → Instagram | Timeline Longevity → Instagram | Timeline Skincare  → Instagram | Jennifer Scheinman  Check Out Courtney:  →  LEAVE US A VOICE MESSAGE →  Check Out My new FREE Grocery Guide! →  @realfoodology →  www.realfoodology.com →  My Immune Supplement by 2x4 →  Air Dr Air Purifier →  AquaTru Water Filter →  EWG Tap Water Database Produced By: Drake Peterson

In this episode, we are joined by Dr. Francisco González-Lima to delve into the metabolic mechanisms that drive brain aging and cognitive decline. He begins by outlining how reductions in cytochrome oxidase activity, disruptions in oxidative phosphorylation, and the accumulation of mitochondrial mutations progressively impair neuronal energy metabolism. These metabolic deficits, he explains, often emerge long before the structural abnormalities associated with Alzheimer's disease. Building on this foundation, the conversation examines how reactive oxygen species, mitochondrial inefficiency, and altered cortical oxygen utilization contribute to diminished cognitive resilience over time. Dr. González-Lima highlights why these metabolic disturbances provide a more coherent explanation for geriatric dementia than traditional protein-centric models. The discussion then shifts to emerging therapeutic strategies. Dr. González-Lima reviews evidence for low-dose methylene blue and 1064 nm transcranial photobiomodulation, both of which appear to enhance mitochondrial respiration and support prefrontal function by directly targeting cytochrome oxidase activity. He concludes by emphasizing the need for metabolism-focused interventions, improved cerebral perfusion, and more precise energy-based frameworks to guide the future of brain-aging therapeutics. Learn more about Dr. Francisco González-Lima: https://liberalarts.utexas.edu/psychology/faculty/fg - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com

In this powerhouse episode, Darin sits down with Catharine Arnston, founder and CEO of ENERGYbits, to explore one of the planet's oldest and most potent foods — algae. From spirulina's superoxide dismutase to chlorella's detoxifying chlorophyll, Catharine breaks down the science of why these tiny organisms hold the key to longevity, energy, detox, and cellular repair. This episode dives deep into the microbiology of health, uncovering how microalgae could solve both human nutrition and planetary sustainability — and why spirulina may truly be "the food of the future."     What You'll Learn in This Episode [00:00] Welcome and intro — algae near the ocean, Darin's long relationship with chlorella and spirulina [00:01:28] The origins of ENERGYbits and Catharine's passion for transparent, toxin-free sourcing [00:03:19] Why algae isn't just another supplement — it's a whole food category of its own [00:04:07] Nutrient density per calorie — the power of bioavailable vitamins, minerals, and proteins [00:05:02] Understanding macroalgae vs. microalgae — why spirulina and chlorella are the real heroes [00:06:15] Why growing algae in freshwater matters — avoiding ocean toxins and micro-contaminants [00:08:06] The global algae revolution — how sustainable "photo bioreactors" may feed the planet [00:10:30] Quality control in algae production — how ENERGYbits preserves nutrient integrity [00:11:18] Spirulina as offense and chlorella as defense — the ultimate nutrition playbook [00:12:58] Why spirulina fuels performance and chlorella drives recovery [00:13:43] Why "food first" is the future of health — and how over-supplementation misses the mark [00:14:25] Algae's 99% absorption rate vs. supplements' 5–10% — the "orchestra" analogy [00:15:06] Phycocyanin — the blue pigment powerhouse behind spirulina's antioxidant strength [00:17:14] Real food vs. isolates — why nature's nutrient matrix always wins [00:18:18] The UN's endorsement: why spirulina could solve world hunger [00:19:13] Bioavailable plant protein — 64% complete protein by weight [00:21:14] How algae creates and saves energy — digestion efficiency and cellular fuel [00:22:02] The chlorophyll connection — nature's blood builder and detoxifier [00:23:32] Why chlorella is a daily detox essential — heavy metals, toxins, and PM2.5 [00:24:43] Chlorella as your daily "internal shower" — detoxing in a toxic world [00:26:59] The antioxidant that saves your mitochondria — superoxide dismutase (SOD) [00:28:32] How SOD prevents inflammation, disease, and aging — and why we lose it after 40 [00:30:46] Why spirulina is nature's richest source of active SOD [00:32:29] Preserving enzymes — why low-temperature processing is everything [00:33:53] Algae's healing power — stories from Hippocrates and Gerson Institutes [00:35:01] The missing human operating manual — how to truly fuel your cells [00:36:07] The symptom isn't the problem — it's the signal your body's sending [00:37:12] Catharine's origin story — how her sister's breast cancer changed her life forever [00:38:32] Discovering alkalinity — Otto Warburg's cancer research and pH balance [00:40:28] The goldfish analogy — why your body's environment determines your health [00:41:32] How feeding fish algae solved oceanic "dead zones" — the alkalinity connection [00:42:22] Disease as slow imbalance — how poor food slowly drains vitality [00:43:06] Why cellular energy equals cellular wealth — mitochondria as your body's power grid [00:44:36] How chronic disease spirals begin — free radicals, mitochondria, and collapse [00:46:11] The alkaline rescue — how algae restores blood charge and vitality [00:48:23] Real food as communication — how nutrients talk to your cells [00:49:25] The mitochondria-light analogy — why spirulina "turns the lights back on" [00:50:51] Mitochondrial health and mental health — the "Brain Energy" connection [00:52:14] Aging naturally vs. declining unnecessarily — how nutrient density extends life [00:52:58] Spirulina puts nutrients in, chlorella pulls toxins out — the perfect pair [00:53:18] Catharine's 15-year algae experiment — her personal health story [00:54:22] Building ENERGYbits from scratch — Shark Tank, $50k, and unstoppable grit [00:55:07] The "Mother Nature" philosophy — how simplicity and consistency heal [00:56:13] Living in alignment — yoga, sleep, sunlight, and algae as core habits [00:57:09] Listening to intuition — following the whisper of your soul, not the ego's noise [00:59:23] The feather touch of purpose — when you follow your calling, life unfolds [01:00:36] Hitting rock bottom to rise higher — the unseen power of persistence [01:02:22] When helping others heals yourself — Catharine's message of divine reciprocity [01:03:00] Closing reflections — Mother Nature as the ultimate mentor   Thank You to Our Sponsors: Pique Tea: Go to www.piquelife.com/darin to get 20% off all products for life and a free starter kit. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order.     Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only  $7.49/month at https://patreon.com/darinolien     Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com     Find More From Catharine Arnston: Buy Algae at Energy Bits: energybits.com Instagram: @catharinearnston Website catharinearnston.com     Key Takeaway "You didn't get sick overnight — and you won't heal overnight. But you can. The recipe is simple: give your body the ingredients Mother Nature designed — sunlight, sleep, breath, movement, and algae. Algae isn't a supplement. It's food. It's your body's operator manual in disguise."  

Nicotine isn't just addictive—it might be one of the most misunderstood nootropics in modern medicine. In this masterclass, you'll learn how controlled, low-dose nicotine may enhance brain performance, boost neuroplasticity, improve mitochondrial function, and potentially extend lifespan. Host Dave Asprey breaks down the surprising science behind this controversial compound, separating fact from fear—and exposing the real risks that nobody talks about. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR You'll discover how nicotine affects neurotransmitters, why it may help with ADHD and focus, and how it compares to other cognitive enhancers like caffeine, nootropics, and even smart drugs. Dave explores how nicotine can be used to hack metabolism, enhance sleep optimization, and support fasting or ketosis protocols—if used properly. He also reveals the forms of nicotine that are safest (spoiler: it's not vapes or cigarettes), how nicotine works at the receptor level, and what the science says about long-term health effects. This episode blends functional medicine, brain optimization, and biohacking into one powerful, myth-busting breakdown. You'll Learn: • How nicotine affects mitochondria, neurotransmitters, and dopamine signaling • Why nicotine may boost neuroplasticity, memory, and attention span • How low-dose nicotine compares to caffeine, modafinil, and other nootropics • The safest delivery forms (and the ones to avoid) • Whether nicotine supports or hinders longevity and cognitive resilience • How it can be stacked with supplements, fasting, or ketosis • What functional medicine says about chronic use, addiction, and withdrawal This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Nicotine microdosing, Nicotinic acetylcholine receptors, Dopamine and motivation, Cognitive enhancement, Alzheimer's prevention, Neuroinflammation, Mitochondrial function, TNF-alpha reduction, Vagus nerve activation, Longevity biohacking, Nicotine vs smoking, Nootropics, Attention and vigilance, Ketosis and metabolism, Functional medicine, Nicotine patches and gum, Addiction and tolerance, Receptor desensitization, Withdrawal protocols, Deep work performance Thank you to our sponsors! -TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. -HeartMath | Go to https://www.heartmath.com/dave to save 15% off. -Leela Quantum Tech | Check out all HEAL360 products and research and get 10% off at https://leelaq.com/DAVE. -Calroy | Head to https://calroy.com/dave for an exclusive discount. Resources: • Business of Biohacking | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Introduction 1:27 — History & Background of Nicotine 4:34 — How Nicotine Works 15:12 — Benefits & Research 16:43 — Risks & Who Should Avoid It 21:39 — Delivery Methods & Dosing 26:30 — Conclusion & Next Steps See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could improve your mitochondria, oxygen efficiency, and recovery in just 20 minutes a day—by breathing energized water? This episode explores one of the most surprising breakthroughs in biohacking and how it can help you live longer, think clearer, and perform better. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey talks with Rowena Gates, co-founder of NanoVi, a therapeutic device backed by biophysics research that supports protein repair and mitochondrial communication. Her work reveals how structured water inside your cells drives neuroplasticity, cellular regeneration, and stress resilience—offering a new pathway to recovery, energy, and longevity. You'll learn how structured water affects mitochondrial efficiency, how it compares to recovery methods like cold therapy and fasting, and why improved VO₂ max may correlate with a longer lifespan. Dave and Rowena also explore how NanoVi stacks with supplements, nootropics, ketosis, and functional medicine to enhance brain optimization, metabolism, and human performance. You'll Learn: • How structured water boosts mitochondrial function and VO₂ max • The difference between hydration and energized cellular water • What happens to your brain and heart rate variability in 20 minutes of NanoVi use • The link between water structure, protein repair, and recovery • How biohackers combine NanoVi with fasting, cold therapy, and sleep optimization for faster results • Why stronger mitochondrial communication can extend lifespan and upgrade cognitive function They explore how structured water, mitochondrial repair, and recovery science intersect to create a smarter approach to health and longevity. You'll also learn how optimizing cellular communication, oxygen efficiency, and stress resilience can accelerate healing, improve focus, and extend lifespan. This is essential listening for anyone serious about biohacking, human performance, and longevity, and for those who want to understand how functional biology and mitochondrial science are redefining recovery, energy, and aging. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: NanoVi, Structured water, Energized water, Biohacking, Dave Asprey, Mitochondrial repair, Mitochondrial communication, Human performance, Longevity, Recovery science, Oxidative stress, Protein repair, Redox signaling, Cellular hydration, Functional medicine, VO₂ max, Neuroplasticity, Brain optimization, Cellular energy, Stress resilience, Cold therapy, Fasting, Sleep optimization, Breathwork, Nootropics, Metabolism, Oxygen efficiency, ATP production, Cellular regeneration, Anti-aging, Smarter Not Harder **To level up your mitochondria with a NanoVi: visit https://eng3corp.com/dave/ ** Resources: • Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:25 — Introduction to NanoVi 4:01 — How to Use NanoVi 6:23 — Understanding Ordered Water 9:16 — Scientific Evidence & Studies 13:02 — Pricing & Accessibility 15:02 — Mitochondrial Function & MiScreen Results 19:55 — Brain Function & Cognitive Benefits 23:47 — How Ordered Water Works 27:34 — Cellular Communication & Fascia 30:14 — Heart Rate Variability & Stress Reduction 34:54 — Athletic Performance & Recovery 38:52 — Mental Health & Sleep Benefits 42:00 — Supplement Stacking 45:50 — Deep Sleep & Parasympathetic State 48:48 — Chronic Conditions & Fatigue 51:54 — Meditation & Brain Training 55:42 — Brain Injury & Resilience 59:36 — Conclusion & Where to Get It See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

AI is transforming medicine at a speed never seen before. In this episode, you'll discover how digital twins and artificial intelligence will revolutionize drug discovery, eliminate human trials, and personalize your biology for longevity and high performance. Host Dave Asprey breaks down how AI can now simulate virtual cells and tissues, running clinical experiments in minutes instead of years to create truly individualized medicine. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Dr. Derya Unutmaz is a world-renowned immunologist, systems biologist, and professor at The Jackson Laboratory. With more than 150 scientific papers, he's a leading expert in immune system research and one of the first scientists to pioneer the concept of digital twins for biology. His groundbreaking work uses AI to model how immunity, metabolism, and aging interact—creating new possibilities for personalized medicine, disease prevention, and lifespan extension. Host Dave Asprey and Dr. Unutmaz reveal how AGI will soon outperform doctors, accelerate functional medicine, and optimize human biology far beyond today's standards. You'll learn how the immune system drives inflammation and aging, how to re-engineer it for resilience, and why compounds like GLP-1 and metformin may add years to your life. You'll Learn: • How digital twins will end human drug testing • Why AGI could replace doctors and computer jobs within five years • How AI models immune function, metabolism, and aging • The role of mitochondria and inflammation in longevity • How GLP-1 drugs and metformin extend lifespan • What continuous biological monitoring means for health tracking • How AI is transforming functional medicine and personalized care • Why NAD and energy metabolism are key to human performance They explore how artificial intelligence, biohacking, and systems biology intersect to create a smarter approach to health and longevity. You'll also learn how understanding immune balance, metabolism, and mitochondrial function helps build resilience and extend your lifespan. This is essential listening for anyone serious about biohacking, hacking human performance, and extending longevity through personalized medicine, functional biology, and cutting-edge AI innovation. This is essential listening for anyone serious about biohacking, hacking human performance, improving mobility, and extending longevity. You'll also learn how neuroplasticity, metabolism, and brain optimization all connect to the way you move. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: AI medicine, Digital twins, Functional medicine, Biohacking, Longevity, Immune system, Inflammation, Personalized medicine, GLP-1 therapy, Metformin, NAD boosters, Mitochondrial function, Metabolism, AGI, Clinical trials, Human performance, Aging research, Systems biology, Immunology, Smarter Not Harder Thank you to our sponsors! BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order Resources: • Keep up with Derya's work: https://x.com/derya_?lang=en • Business of Biohacking Summit | Register to attend October 20-23 in Austin, TX https://businessofbiohacking.com/ • Danger Coffee: https://dangercoffee.com/discount/dave15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 00:00 — Trailer 01:25 — Intro 02:26 — AI's Role in Extending Lifespan 02:56 — Regulatory Frameworks and Medical Adoption 05:19 — Problems with the Immune System 08:19 — Chronic Fatigue and Long COVID Research 10:32 — Modern Testing and Multi-Omic Analysis 14:07 — Personal Longevity Strategy and Supplements 15:17 — Understanding Exhausted Cells 23:43 — Personalization in Medicine and AI Analysis 31:35 — Longevity Escape Velocity 36:13 — AI Doctors and Prescriptions 39:55 — Data Quality Concerns in AI Training 43:19 — The Future of Wearable Technology 45:50 — Revolutionizing Education with AI 49:04 — The Future of Higher Education 52:03 — Future of Work and AI Agents See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.