organelle in eukaryotic cells responsible for respiration
POPULARITY
Categories
Feeling exhausted no matter how much you rest? Wondering if adrenal fatigue, hormone imbalance, or chronic stress are wrecking your health? In this episode, Juanique sits down with Dr. Brian Rodgers to break down the hidden connections between your adrenals, thyroid, mitochondria, and overall energy — and why most doctors miss adrenal burnout completely.You'll learn exactly why adrenal recovery is key for lasting hormone balance and how functional medicine takes a different approach to healing.What You'll Learn:✔ How the HPA axis controls your stress, cortisol, and energy✔ Why your mitochondria must be fixed before adrenal recovery can work✔ How poor gut health blocks nutrient absorption and slows healing✔ The three stages of adrenal burnout — and how to tell which you're in✔ Why chronic stress, over-exercising, and stimulants can backfire✔ How functional medicine treats adrenal fatigue when conventional doctors won't✔ What CIRS (chronic inflammatory response syndrome) is — and why it shuts down healingTimestamps:00:00 — Introduction: Why adrenal health is step five in the healing process05:00 — Juanique's personal adrenal burnout journey10:00 — Understanding the HPA axis and hormone signaling15:00 — Mindset, brainwave patterns, and stress responses20:00 — Mitochondrial function: Why it comes before adrenal healing25:00 — Gut health, inflammation, and nutrient absorption30:00 — Liver detox and clearing excess cortisol35:00 — What CIRS is and how it hijacks your body40:00 — The three stages of adrenal fatigue (and why most doctors miss them)50:00 — Why stimulants, caffeine, and over-exercising make burnout worse01:00:00 — How to start rebuilding adrenal function01:05:00 — How the Gutsy Health Academy teaches you to become your own best health advocateResources & Next Steps:→ Join the Gutsy Health Academy waitlist for the next intake: https://www.mygutsyhealth.com/academywaitlist→ Book a consult or learn more about Provo Health: 801-691-1765 or provohealth.com → Follow Juanique for updates and insights: @gutsy_momSend us a text
In this deep and vulnerable solo episode, I'm sharing what aging in your 30s really means—and why I believe it's the most important decade for longevity. From collagen loss and hormonal shifts to red light therapy, building muscle, and navigating mitochondrial decline—I'm blending science-backed insights with soul-led reflections to help you glow deeper and age slower. If you're craving better skin, more energy, or just want to feel like yourself again, this episode is your roadmap to aging well—biologically, emotionally, and energetically. I TALK ABOUT: 03:50 – Why your 30s are the gateway to long-term wellness 08:50 – The biology of aging: Collagen, mitochondria, hormones, and inflammation 14:10 – Protein and muscle: What every woman should be doing for strength (BiOptimizers code: BIOHACKINGBRITTANY, NOVOS code: BIOHACKINGBRITTANY) 20:10 – Sugar, cravings, and the emotional root of fatigue 26:50 – Red light therapy, peptides, and tools for skin optimization (Muskoka Tallow code: BIOHACKINGBRITTANY, OneSkin code: BIOHACKINGBRITTANY, HigherDose code: BRITTANY15, Tiny Health code: BIOHACKINGBRITTANY, Dutch test, Platt code: BRITTANY) 33:50 – Mitochondrial decline: Signs, symptoms, and how to reverse it (spermidineLIFE code: BIOHACKINGBRITTANY, Fatty15 code: BIOHACKINGBRITTANY, Kineon code: BIOHACKINGBRITTANY) 38:30 – Cold plunges, sauna, and other lifestyle practices that matter 41:00 – Aging as a spiritual and emotional transformation 45:50 – Nervous system regulation as the ultimate anti-aging tool (Pulsetto) 53:00 – The one question to ask yourself about soul alignment and aging SPONSORS: Pique's Sun Goddess Matcha and BT Fountain Electrolytes deliver clean, science-backed support— use my link to get 20% off plus a free frother and beaker. RESOURCES: Optimize your preconception health by joining my Baby Steps Course today! Optimize your preconception health and fertility through my free hormone balancing, fertility boosting chocolate recipe! Download it now! Check out my upcoming luxury retreats and wellness events My Amazon storefront LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music
In this solo episode of The Red Light Report, Dr. Mike explores the profound connection between mitochondrial health and oral disease. He reviews three recent studies highlighting how red light therapy, methylene blue, and compounds like urolithin A can support oral tissues, reduce inflammation, and even impact systemic conditions like diabetes and neurodegeneration. From root canal innovations to mitophagy in periodontitis, this episode is full of cutting-edge insights and practical applications for anyone interested in longevity, biohacking, or oral health optimization.Key Topics Covered:Study #1: Methylene Blue + Graphene Oxide for Root Canal Photodynamic Therapy• Combining methylene blue and reduced graphene oxide with red light therapy significantly improves antibacterial and antifungal effects in root canals.• Highlights the synergy between methylene blue and red light.• Dr. Mike shares how his nighttime routine—using BioBlue Calm and a red-light toothbrush—may create a low-level photodynamic therapy effect in the mouth.Study #2: Mitophagy in Periodontal Disease• Mitophagy (mitochondrial autophagy) plays a key role in managing inflammation, bone remodeling, and cell death in gum disease.• Key interventions to enhance oral mitophagy:• Urolithin A (strong Pink1/Parkin pathway activator)• Resveratrol, Melatonin (support mitochondrial quality)• Berberine, Curcumin, Metformin (via AMPK activation)• NR, Quercetin (via SIRT1 + PGC-1α pathway)Study #3: Mitochondrial Dysfunction Links Oral and Systemic Diseases• Periodontitis driven by mitochondrial dysfunction is linked to diseases like diabetes, cardiovascular disease, and neurodegeneration.• Key issues:• Impaired mitochondrial fusion/fission, biogenesis, and mitophagy.• Excessive ROS and mitochondrial DNA leakage fuel inflammation.• Poor mitochondrial function impairs periodontal stem cell regeneration.• Therapeutic approaches:• Antioxidants (CoQ10, resveratrol, melatonin, curcumin, EGCG)• Photodynamic therapy (methylene blue + red light)• Mitochondria-targeted compounds to modulate apoptosis and inflammation.Dr. Mike's Takeaways• Oral mitochondrial health is foundational—not isolated from systemic health.• Red light therapy and methylene blue offer powerful synergistic effects, even in oral applications.• A mitochondria-first approach may provide long-term protection against oral and systemic disease. If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: 00:00 – Introduction: Mitochondrial Health & Podcast Focus 00:32 – Announcements: Health Alchemy Bundle & Upcoming Events 06:18 – Study 1: Methylene Blue & Red Light Therapy for Root Canal Treatment 08:42 – Methylene Blue Benefits Recap 13:37 – Study 1 Discussion: Photodynamic Therapy Enhancements 16:57 – Practical Application: Methylene Blue for Oral Health 19:40 – Study 2: Mitophagy in Periodontal Disease 23:46 – Targeted Mechanisms to Enhance Mitophagy 28:42 – Study 3: Mitochondrial Dysfunction in Periodontitis & Systemic Diseases 31:38 – Therapeutic Strategies for Mitochondrial Health 41:44 – Integrative Mitochondrial Therapies 47:02 – Conclusion: Mitochondrial Dysfunction as a Core Issue 50:45 – Closing Thoughts & Upcoming Events - Articles referenced in episode:Synthesis, characterization, and application of methylene blue functionalized reduced graphene oxide for photodynamic therapy in root canal treatmentMitophagy and Its Significance in Periodontal DiseaseMitochondrial Dysfunction in Periodontitis and Associated Systemic Diseases: Implications for Pathomechanisms and Therapeutic Strategies - Get over $6,000 worth of wellness education from top experts for $50! The Health Alchemy BundleThis is an amazing opportunity put together by Carrie Bennett and Sarah Kleiner! This Bundle is collection of 60+ eBooks, courses, and other resources available for $50 at a mind-blowing 99% discount. This massive collection of resources is rooted in the science + spirituality of healing with nature, which cover topics like: Circadian & quantum biology Mental, emotional, & spiritual health Nutrition, minerals, & supplementation (when necessary) Herbalism & homeopathy Movement, posture, & fitness Hormonal health, pregnancy, & parenting And even specific issue support—from healing autoimmunity to improving sleep, & more This is a limited opportunity that goes through TOMORROW, May 23rd, so act now and don't miss out! Get The Health Alchemy Bundle by clicking here! - Upcoming BioLight Events: Biohacking Conference - May 28 - 30 (Austin, TX) Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Introducing the Newest BioBlue Supplement! The most comprehensive, powerful mitochondrial support supplement on the market ... What is The Fountain of Youth in simple terms? An unparalleled supplement for brain power, energy, and longevity This supplement is like a high-performance tune-up for your brain and body. It combines powerful natural and science-backed ingredients to help you think clearer, feel more energized, and support your long-term health.The BioBundle automatically saves you 15% on both of the supplements you choose. For the next two weeks, SAVE 20% on your order of BioBlue Fountain of Youth! Simply use code FOY20 Code expires 5/29, midnight PST Click here to check out BioBlue Fountain of Youth - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn BioLight: Website Instagram YouTube Facebook
In this episode of the Ageless Future Podcast, Cade Archibald takes listeners on a deep dive into the powerful peptide SS-31 and its role in enhancing mitochondrial health. He explains how SS-31 stabilizes mitochondrial membrane potential, reduces oxidative stress, and protects key structures like cardiolipin to boost ATP production and energy in aging or stressed cells. With potential applications for metabolic health, Alzheimer's, diabetes, and recovery from ischemic injuries, SS-31 emerges as a game-changing therapeutic peptide. Tune in to learn how this “mitochondrial protector” supports longevity, energy, and cellular performance from the inside out. www.agelessfuture.com
Brandon Eisenlauer, aka @BiohackingUThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder:[ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]https://transcendcompany.com/patient-intake-form/?ls=Nyle+NaygaWatch it: https://www.youtube.com/watch?v=6Ihq4tIzyS8&t=5618sRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program: https://www.nylenaygafitness.comTimestamps:00:00 – Intro08:28 – Neuro-toxicity of popular PEDs (19-nors, Tren, etc.)11:42 – Brain-basics: Neuro-steroid support16:18 – Dopaminergic Life & Consequences21:32 – Real Risk of Bodybuilding, Rest & The Right Way27:04 – Managing Mental Stress: Meditation & Mindful Break38:30 – Gen Z, Motivation Gaps & “Just Go Live Life”41:17 – Independence & Growth42:46 – Psychedelics & Neuroplasticity43:45 – Hustle Culture vs Balance46:40 – Cultural & Political Extremes48:40 – Finding Balance in Bodybuilding52:19 – Conscientious Growth53:50 – Brain Protection Strategies57:01 – Serotonin & SSRI Benefits58:33 – Cholinergic, Sleep Support & GABA System1:03:30 – SSRIs Stigma & Pharma Bias1:12:45 – Best Cycle Principles1:19:38 – Pharmacology Caveats & Nuance1:25:25 – Finding Reasons Is Hard & Adaptation1:27:52 – Mitochondrial & Estrogenic Peptides1:36:14 – Stimulant Cycling Strategy & Risks1:47:10 – Injectable Amino Blends1:52:17 – Peptide Safety & Cancer1:57:36 – Skin Health & Peptides1:59:46 – The Final Question
Back on the show for a second time is Dr. Jack Kruse, a neurosurgeon and health optimizer who takes a unique approach to wellness through what he calls "quantum biology." Dr. Kruse has dedicated his career to exploring the connection between light, electromagnetism, and human health. He's known for his controversial perspectives on how modern technology, artificial light, and high-latitude living negatively impact our cellular function and mitochondrial health.Watch our first podcast with Dr. Kruse here: https://youtu.be/luMHcGTAhA8Dr Kruse Links:https://x.com/DrJackKrusehttps://www.instagram.com/drjackkrusehttps://www.patreon.com/DrJackKrusehttps://jackkruse.comWelcome to take a deep breathFree Resources:
Dr. Chris Winfrey practices neuropsychiatry in private practice at New Image Wellness, in Marlton, NJ. His practice is a blend of orthomolecular psychiatry, functional medicine, and psychoanalytic therapy. He uses this combination of medicine towards conditions such as Traumatic Brain Injuries, Cognitive Impairment, PANDAS, Mold Toxicity induced Encephalitis, refractory depression, complex PTSD and other conditions to rehabilitate the brain and restore mental functioning. Key Topics: - What conventional psychiatry is missing right now - How thyroid plays a role in energy and why simply taking your temp daily could make a difference - The connection between mitochondrial function and brain health - How your overall toxic load is hindering your mental wellness - PH balance: the nutrition puzzle piece we often miss - Mold toxicity and its impact on mental health - ADHD is more than just a dopamine issue - Lyme disease and the psychological impact of vector-borne disease Learn more about Dr. Winfrey at https://drchriswinfrey.com/ and newimagewellness.net Join Erin's monthly mailing list to get health tips and fresh meal plans and recipes every month: https://mailchi.mp/adde1b3a4af3/monthlysparksignup Preorder Erin's new book, Live Beyond Your Label, at erinbkerry.com/upcomingbook/
I was very excited to discuss how to restore and reset mitochondrial health with expert, Dr. Paul Anderson. In this episode, we'll review the function of the mitochondria, signs you may be dealing with dysfunction and the best treatments for optimal healing. Tune in now! Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/ Follow Dr. Anderson: Instagram.com/draonline https://www.facebook.com/DrAndersonOnline/ https://dranow.com/ Featured products: https://affordablehyperbaricsolutions.com/hyperbaric-chambers/
Revolutionizing Regenerative Medicine: The Power of Mass-Produced Mitochondria: Nutritionist Leyla Muedin explores groundbreaking research on stem cell-based methods to mass-produce human mitochondria, which could revolutionize regenerative and anti-aging medicine. She delves into the science and potential health benefits, discussing how increased mitochondrial production can improve conditions like osteoarthritis, heart disease, and neurodegenerative disorders. Leyla also provides practical advice on ways to enhance mitochondrial health through dietary and supplement strategies, offering listeners actionable steps to boost their health span and lifespan.
Welcome to the Mind Muscle Connection Podcast!In today's episode, we're joined by Kristi Storoschuk a PhD candidate who studies exercise physiology. We deep dive into the topic of From Fasted Training to Mitochondrial Health.Kristi discussed about how fasted training affects your training, the specifics of what research suggests about how Mitochondrial plays a role in your energy, metabolism and more.If you're trying to figure out if fasted training is right for you and want to understand Mitochondrial, this episode is for you!Let's talk about:Introduction to Kristi StoroschukNutritionTrainingFasted TrainingMitochondrial HealthHypertrophyFinal takeawayWhere to find KristiFollow Kristi on Instagram HEREHer website HEREHer LinkedIn HEREHer X account HEREFollow me on Instagram for more information and education: @jeffhoehn_FREE 30 Min Strategy Call: HEREBody Recomp Checklist 2.0 HERENutrition Periodization Masterclass: HEREHow You Can Work With Me?: HERECoaching application: HEREBody Recomp Checklist 2.0: HERE
Would you like to try a safe method of healing? Do you know about Red Light Therapy? Lisa continues the conversation today with Dr. Carl Rothschild and Joyce Gerber, who also joins us, to talk about the multiple benefits of this therapy. Dr. Rothchild has been a chiropractor for many decades. Nearly 30 years ago, he was introduced to a healing method known as “Red Light Therapy.” Joyce Gerber, who is an expert nutritionist and colon hydrotherapist, met Dr. Carl Rothschild during the pandemic lockdown. Joyce was not able to do hands-on therapy, so she began working with Dr. Rothschild on his Red Light Therapy beds. She met a client who had heart problems. After 5 minutes, the therapy helped his heart tremendously. They explain how we are in a state of regeneration or degeneration. Joyce talks about how she also uses food as therapy. She looks at the whole body and how one part affects another. It's a holistic approach. The remedies are personalized. It's a powerful modality. Joyce explains how nutrition helps as well. Dr. Carl talks about how each session is 12 minutes. He says there have been no recorded side effects from this therapy. Your body will respond whether it needs to relax or be energized. The body knows how to get better. If you have any condition, the therapy may help. Mitochondrial activity is increased, and it will improve those particular areas. It is whole body healing. Dr. Carl explains that not only will you look better and feel better, you will have a better quality of life. Everyone can benefit from this non-invasive treatment. Joyce Gerber calls the mitochondria the energy factories of the cell. They are necessary for optimal health. Dr. Carl also discusses pain and the underlying causes. When corrected, the pain and inflammation go away. You must correct the underlying issues, and you can also reverse them with Red Light Therapy. He also discusses the difference between infared saunas using far-infared and the therapy beds. The near-infared waves affect the mitochondria. He also discusses blue and green lights too, and how blue light can negatively affect sleep patterns. The Red Light wavelengths are invisible to the naked eye. He talks about how there are more than 3 million documents and articles about the benefits of this therapy including studies from the National Institutes of Health. He further discusses how the therapy can also improve mood, sleep, and emotions. There are numerous locations around the country which have the Red Light Therapy Beds. This is Part 2 of the interview. Info: www.trifectalight.com/joyce
In this episode, I share the 4 main ascension themes for May and how they're showing up in our bodies, our voice, and our planetary work! I also offer updates about upcoming gatherings, my transition away from 1:1 sessions, and what's unfolding in our collective field.Mitochondrial updates through breathWeaving multi-galactic frequencies with Light LanguageActivating etheric vaults of wisdomPreparing for the collective crystalline templatesLet's calibrate together and anchor in what's ready to emerge!
Dr. Jaban Moore joins me to share his journey from being a strong, healthy med student to facing debilitating illness that conventional medicine couldn't explain. His experience led him to explore deeper layers of health, focusing on mitochondrial function, nervous system regulation, and terrain-based healing.Now, Dr. Moore helps people of all ages build true resilience by optimizing cellular and nervous system health. In this episode, we talk about simplifying wellness, customizing care, and navigating everything from circadian rhythms to GLP-1s and hormone support.Topics Discussed: What causes mitochondrial dysfunction and how can it affect overall health?How does nervous system retraining support healing from chronic illness?What are terrain resets and why are they important for long-term wellness?How can personalized health protocols improve outcomes compared to standard treatments?What role do GLP-1 medications and hormone support play in functional medicine?No Timestamps: 00:00:00 - Introduction 00:03:34 - Dr. Jaban's backstory 00:08:03 - Mitochondrial health 00:12:14 - Understanding the nervous system 00:15:18 - Nervous system retraining 00:17:57 - The work to support the nervous system 00:20:22 - Terrain resets 00:26:19 - Fad diets & finding what works for you 00:30:02 - Simplifying health 00:34:45 - Importance of custom care 00:36:13 - Circadian health 00:38:51 - Hormonal health00:44:02 - HRT 00:47:14 - GLP1s & supplementation 00:52:17 - Creating health protocols 00:55:48 - Where to find Dr. Jaban Sponsored By: Viva Rays | Go to vivarays.com & use code: YOGI to save 15%Check Out Dr. Jaban: https://www.redefiningwellnesscenter.com/dr-jabanInstagram Facebook This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________My free product guide with all product recommendations and discount codes:https://s3.amazonaws.com/kajabi-storefronts-production/file-uploads/sites/2147573344/themes/2150788813/downloads/eac4820-016-b500-7db-ba106ed8583_2024_SKW_Affiliate_Guide_6_.pdfCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) - https://www.sarahkleinerwellness.com/coursesSign up for my newsletter to get special offers in the future! -https://www.sarahkleinerwellness.com/contact
In this energizing episode, Regan Archibald dives deep into the remarkable benefits of MOTS-c, a mitochondrial-derived peptide that's transforming how we think about energy, metabolism, and aging. Regan shares cutting-edge research on how MOTS-c boosts muscle recovery, enhances insulin sensitivity, activates AMPK, and even mimics the effects of exercise. He also explains how to naturally activate MOTS-c through exercise and sauna use, plus the optimal ways to stack peptides for maximum vitality. Listeners will learn practical strategies to benchmark their energy, improve recovery, and potentially reverse biological aging. Regan also shares personal stories of biohacking success and offers a new weekly challenge to supercharge your energy. Stay tuned for actionable insights and get ready to unleash your mitochondrial power! www.agelessfuture.com
Watch Here : https://www.youtube.com/watch?v=pG19_Yc91Co Website: https://vigoroussteve.com/ Consultations: https://vigoroussteve.com/consultations/ eBooks: https://vigoroussteve.com/shop/ YouTube Channel: http://www.youtube.com/user/VigorousSteve/ Workout Clips Channel: https://www.youtube.com/channel/UCWi2zZJwmQ6Mqg92FW2JbiA Instagram: https://instagram.com/vigoroussteve/ TikTok: https://www.tiktok.com/@vigoroussteve Reddit: https://www.reddit.com/r/VigorousSteve/ PodBean: https://vigoroussteve.podbean.com/ Spotify: https://open.spotify.com/show/2wR0XWY00qLq9K7tlvJ000 Patreon: https://www.patreon.com/vigoroussteve
In this groundbreaking episode of Health Confidential, host Simone Gisondi sits down with Dr. Thomas Seyfried, a pioneering researcher and professor at Boston College, to challenge everything you think you know about cancer. Moving beyond the conventional genetic model, Dr. Seyfried presents compelling evidence that cancer is, in fact, a metabolic disease—a theory with powerful implications for prevention, treatment, and recovery.Through science-backed insights and decades of research, Dr. Seyfried explores how cancer cells thrive on glucose and how therapeutic strategies like the ketogenic diet, fasting, and metabolic therapies can starve cancer at its root. Together, Simone and Dr. Seyfried uncover what this paradigm shift means for patients and practitioners alike—and why addressing mitochondrial health may be the missing piece in truly healing cancer.This is an essential listen for anyone touched by cancer, seeking truth, or looking for hope beyond the mainstream narrative.KEY TAKEAWAYSCancer is not just a genetic disease—it's primarily a metabolic disorder.Nutrition and metabolic therapy play a pivotal role in disrupting cancer growth.Ketosis and fasting can be powerful tools in targeting cancer's fuel source.Mitochondrial dysfunction is at the heart of many chronic diseases, including cancer.Understanding the root cause of cancer changes how we approach healing.BEST MOMENTS “Cancer isn't something you catch—it's something your body can no longer control.” “If you deprive cancer of its fuel, it can't survive.” “We have more power than we realize when it comes to preventing and treating cancer.”GUEST INFORMATIONDr. Thomas SeyfriedPh.D. in Genetics and Biochemistry | Author, Cancer As A Metabolic DiseaseWebsite: https://tomseyfried.com/ Instagram: thomasseyfriedbcVALUABLE RESOURCES
Are your mitochondria aging faster than you are? In this episode, Dr. Mark Tarnopolsky breaks down the central role of mitochondria in aging, longevity, and overall metabolic health. Learn how mitochondrial dysfunction drives age-related decline, including neurodegenerative diseases, and what you can do about it. From the paradox of oxidative stress to the risks of overusing antioxidants, this conversation unpacks what actually supports mitochondrial health—including a clinical “mitochondrial cocktail” targeting multiple aging pathways. Dr. Tarnopolsky also explains how exercise, nutrition, VO2 max, and exokines impact your healthspan, plus why most therapeutics miss the mark. Learn more about Dr. Mark Tarnopolsky: https://experts.mcmaster.ca/display/tarnopol
Welcome back to the Flex Diet Podcast! I'm Dr. Mike T. Nelson, and in this episode, I sit down with Dr. Hamal Patel, Chief Scientific Advisor to Discovery and the brilliant mind behind the ME screen blood test for mitochondrial function.We dive into Dr. Patel's fascinating journey into the world of mitochondrial research, how mitochondria impact everything from metabolism to resilience, and why he developed a personalized blood test to better understand mitochondrial health. We also get into some really cool topics like how heat and cold exposure affect your mitochondria, the intersection of meditation and cellular health, and even the emerging role psychedelics might play in this space.Dr. Patel also shares his top tips for optimizing mitochondrial function and explains the science behind this cutting-edge testing method. If you're curious about performance, longevity, or just want to geek out on mitochondria with two scientists, this episode is for you. Let's dig in.Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comDaily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Flex 4: Dr. Patel's top 4 recommendations to improve mitochondriaTriphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:05:51 Dr. Patel's Journey into Mitochondrial Research08:34 Heat and Cold Stress in Mitochondrial Function12:18 Mitochondrial Function and Health19:50 Innovative Mitochondrial Testing31:05 Understanding Mitochondrial Respiration31:20 Testing Mitochondrial Efficiency31:51 Energy Production Pathways32:24 Free Radical Generation and Stress Testing32:58 Exercise Physiology and Mitochondria33:50 Personalized Mitochondrial Health Recommendations33:59 The Complexity of Mitochondrial Adaptation37:28 The Role of Membranes in Mitochondrial Health38:49 Oxygen's Dual Role in Life and Aging41:05 Preconditioning and Cardiovascular Health43:07 Hypoxic Training and Breath Work43:50 Meditation and Mitochondrial Function48:03 Psychedelics and Mitochondrial Changes54:33 Practical Tips for Mitochondrial Health56:12 Conclusion and Final ThoughtsFlex Diet Podcast Episodes You May Enjoy: Episode 164: How to use diagnostic testing to improve your metabolic health: An Interview with Sam MillerEpisode 190: Let's Get Woo Woo – From Physics To Scientific Testing To Exercise Performance with Ian Mitchell of Wizard SciencesConnect with Dr. Patel: Instagram: https://www.instagram.com/hemalpatelphd/Website: https://mescreen.com/Enter code DRMIKE to save $100 - I don't make a dime off it. I would love to hear what you find, so hit me up if you try it!Get In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/
In this episode, Dr. Adam Rinde sits down with integrative medicine specialist Dr. Carla Kuon from University of California San Francisco (UCSF) to explore the latest insights into long COVID, chronic fatigue syndrome, and post-viral illnesses. Dr. Kuon shares powerful breakthroughs from her clinical work and research—especially around mitochondrial health and how overlooked deficiencies in riboflavin (B2) and iron (ferritin) can disrupt the body's energy systems.You'll learn how chronic inflammation, nervous system dysregulation, and “bad programming” in the brain are key components of these conditions—and how holistic strategies like nutrient therapy, mindfulness, and vagus nerve stimulation are helping patients recover.Whether you're a patient, provider, or just curious about the future of functional medicine, this conversation is full of takeaways and hope.
In this episode of the Fit Mother Project podcast, Dr. Anthony Balduzzi interviews Connie Zack, co-founder of Sunlighten, about the transformative power of infrared technology and saunas. Connie shares her personal journey into the world of infrared, driven by a desire to help others achieve better health. The conversation delves into the science behind aging, the role of infrared in enhancing mitochondrial health, and its benefits for detoxification and gut health. Connie emphasizes the importance of far infrared as a foundational element for wellness and discusses how it can positively impact various systems in the body, including stem cell vitality and cellular senescence. In this conversation, they discuss the benefits of infrared saunas, focusing on personal routines, therapeutic advantages, skin health, and the customer experience with Sunlighten products. Connie shares her sauna routine, emphasizing the importance of personal preference and the therapeutic benefits of infrared energy. They speak about how infrared saunas can enhance skin health and aesthetics, promoting collagen production and detoxification. The discussion also highlights the customer-centric approach of Sunlighten, ensuring that individuals find the right products for their wellness journey.Key TakeawaysInfrared technology can detoxify the body naturally.The goal of Sunlighten is to spread hope and health.Infrared affects every system in the body positively.Mitochondrial health is crucial for energy and longevity.Cellular senescence can be addressed with infrared.Far infrared is foundational for health benefits.Infrared supports gut health and detoxification.Regular use of infrared can enhance stem cell vitality.Infrared can significantly impact aging processes. Therapeutically, sauna use can be done at any time of day.Infrared saunas provide energy transfer without needing high temperatures.Skin health benefits include improved collagen and elastin production.Hydration and electrolyte balance are crucial during sauna use.Sunlighten offers a personalized customer experience for product selection.The Lumineer provides portable near-infrared therapy for skin health.Combining red and near-infrared light enhances therapeutic effects.Detoxification occurs through various bodily processes, not just sweating.Self-care practices like sauna use contribute to overall happiness and well-being.Where You Can Learn More:Website: https://get.sunlighten.com/fitfatherprojectSunlighten is offering some awesome savings - up to $600 off your sauna purchase.Facebook: https://www.facebook.com/SunlightenSaunas/Instagram: https://www.instagram.com/sunlightensaunas/Pinterest: https://www.pinterest.com/sunlighten/_created/YouTube: https://www.youtube.com/@SunlightenSaunasLinkedIn: https://www.linkedin.com/company/sunlighten/Biographical Information on Connie Zack, co-founder of Sunlighten, the world leader in infrared sauna and light therapy, was inspired by her brother's health transformation through infrared sauna use. She and her husband, Aaron, left successful...
EP 205: Catharine Arnston, founder and Chief Scientific Officer of ENERGYbits, is back for another fascinating conversation—this time focused on women's health, hormones, and the power of algae. We dive into how spirulina and chlorella support mitochondrial function, balance hormones, and deliver potent antioxidant benefits, all grounded in decades of research. Catharine's passion for algae began when her sister fell ill, sparking a journey that led to the creation of ENERGYbits. Her deep knowledge and infectious enthusiasm make this a must-listen for anyone curious about how a simple, sustainable superfood can make a big impact. Check Out ENERGYbits | Click Here & use code DRTYNA for 20% off Topics Discussed: How does algae support women's hormonal health and balance? What are the benefits of spirulina and chlorella for mitochondrial function? Can algae help with symptoms of perimenopause and menopause? Why is algae considered one of the most nutrient-dense superfoods? How do antioxidants in algae improve overall health and energy levels? On This Episode We Cover: 00:00:00 - Introduction 00:02:20 - Manufacturing process 00:04:22 - Different types of algae 00:06:37 - Manufacturing process 00:12:49 - Vegan collagen 00:14:43 - Mitochondrial health & estrogen 00:19:32 - Perimenopause 00:26:11 - Women's aging & hormone health 00:28:49 - Estrogen levels 00:34:55 - Dr. Tyna's experience with ENERGYbits 00:38:04 - Carnivore diet & chlorophyll 00:40:50 - Red light 00:45:43 - B Vitamins & decision fatigue 00:47:31 - Constipation 00:49:53 - Aging and finding joy 00:56:04 - Testimonials Further Listening: EP. 139: Algae 101 | Catharine Arnston of Energy Bits Hormones Playlist Sponsored By: ENERGYbits | Click Here & use code DRTYNA for 20% off Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.
Methylene blue has been going viral recently and not always for the right reasons.... or so their claimers make it seem. The most recent example of this is Dr. Paul Saladino's video he posted on social media he states that methylene blue actually "decreases ATP production" amongst other rationales for why people should not be consuming this mitochondrial-boosting agent. In the beginning of todays episode, I thoroughly and clearly state my thoughts on Dr. Saladino's hot take.The second topic entails a prelude about deuterium: what it is, how it impacts our mitochondrial function and some strategies to help mitigate its negative effects. We first discuss deuterium, because the research article we cover today is about taurine and its implications for helping the body produce deuterium-depleted water and/or helping the body decrease its deuterium content altogether. This not only has implications for overall health, but countless diseases and cancers as well. If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: •00:25 – Upcoming Health Optimization Summit and new BioLight product •02:20 – Responding to Paul Saladino's methylene blue criticism •04:14 – Why understanding mitochondria is critical for health •05:54 – Mitochondrial dysfunction behind 80% of modern diseases •08:37 – Clarifying research on methylene blue and ATP production •10:16 – Layman summary of study supporting methylene blue benefits •12:26 – Introducing the BioLight Cocoon for full-body therapy •15:03 – Methylene blue boosts energy, especially with poor mitochondria •16:46 – Addressing methylene blue brain staining concerns •19:03 – Importance of methylene blue quality and detox pathways •20:38 – The problem with click-driven health influencers •21:40 – Encouraging fact-checking and personal research •23:17 – What deuterium is and why it harms mitochondria •28:09 – Common sources of deuterium in food and water •33:08 – How to lower deuterium through diet and habits •35:17 – Taurine's powerful impact on mitochondrial function •39:30 – Taurine helps reduce oxidative stress and improve energy •41:23 – Taurine's role in gut health and deuterium balance •46:51 – Study shows taurine protects mitochondria from deuterium •50:39 – Taurine and deuterium-depleted water for cancer support •52:12 – Why taurine is in BioBlue capsules •54:17 – Final thoughts and upcoming events - Article referenced in episode: Taurine prevents mitochondrial dysfunction and protects mitochondria from reactive oxygen species and deuterium toxicity - Upcoming BioLight Events: Health Optimisation Summit (Biohacking Conference), April 12 - 13 (Austin, TX) Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Save 25% when you Subscribe & Save to a BioBundle! For a BioBundle, you choose:1.) Any one BioBlue supplement(BioBlue, BioBlue (SR), BioBlue Leuco, BioBlue Calm, BioBlue Capsules or BioBlue Leuco Capsules)2.) Any one BioC60 supplement(Regular or Concentrated) The BioBundle automatically saves you 15% on both of the supplements you choose.You save an additional 10% by choosing to Subscribe & Save to that BioBundle.The 25% savings is passed along for every monthly delivery of your BioBundle!No discount code necessary! Click here to check out The BioBundle - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn BioLight: Website Instagram YouTube Facebook
Paula Cilleros-Holgado from Pablo de Olavide University discusses a #research paper she co-authored that was #published in Volume 17, Issue 2 of Aging (Aging-US), entitled “Mitochondrial dysfunction, iron accumulation, lipid peroxidation, and inflammasome activation in cellular models derived from patients with multiple sclerosis.” DOI - https://doi.org/10.18632/aging.206198 Corresponding author - José Antonio Sánchez-Alcázar - jasanalc@upo.es Video interview - https://www.youtube.com/watch?v=wIV0lAHPA_M Abstract Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Despite advancements in managing relapsing active illness, effective treatments for the irreversible progressive decline in MS remain limited. Research employing skin fibroblasts obtained from patients with neurological disorders revealed modifications in cellular stress pathways and bioenergetics. However, research using MS patient-derived cellular models is scarce. In this study, we collected fibroblasts from two MS patients to investigate cellular pathological alterations. We observed that MS fibroblasts showed a senescent morphology associated with iron/lipofuscin accumulation and altered expression of iron metabolism proteins. In addition, we found increased lipid peroxidation and downregulation of antioxidant enzymes expression levels in MS fibroblasts. When challenged against erastin, a ferroptosis inducer, MS fibroblasts showed decreased viability, suggesting increased sensitivity to ferroptosis. Furthermore, MS fibroblasts presented alterations in the expression levels of autophagy-related proteins. Interestingly, these alterations were associated with mitochondrial dysfunction and inflammasome activation. These findings were validated in 7 additional patient-derived cell lines. Our findings suggest that the underlying stress phenotype of MS fibroblasts may be disease-specific and recapitulate the main cellular pathological alterations found in the disease such as mitochondrial dysfunction, iron accumulation, lipid peroxidation, inflammasome activation, and pro-inflammatory cytokine production. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206198 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, multiple sclerosis, iron accumulation, lipid peroxidation, inflammasome, mitochondrial dysfunction To learn more about Aging (Aging-US), please visit our website at https://www.Aging-US.com and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
150 - What If Your Brain Fog Isn't All In Your Head? 7 Fixes You've Never TriedIf you've ever walked into a room and immediately forgotten why you're there, you'll want to hear this. What if your brain fog isn't just a coffee shortage… but a mitochondrial meltdown? In this episode of the Pretty Well Podcast, we're digging into the real root of brain health—your mitochondria. Yep, those tiny powerhouses are pulling more weight than you think. You'll learn 7 simple, science-backed ways to boost your brain clarity, energy, and focus (without adding 42 more supplements to your cart). If you're dealing with forgetfulness, low energy, or feeling like your brain's operating on dial-up, this one's for you. We're talking longevity, cognitive vitality, and how to keep your brain as sharp as your wit. Think of it as a tune-up for your brain; real ways to support long-term cognitive health so you can stay sharp, focused, and actually remember where you put your keys.Links & Resources:Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke; Arch Neurol. 2004;61(6):889-892. doi:10.1001/archneur.61.6.889https://jamanetwork.com/journals/jamaneurology/fullarticle/786017#google_vignetteEffects of Coenzyme Q10 on Statin‐Induced Myopathy: An Updated Meta‐Analysis of Randomized Controlled Trials; Journal of the American Heart AssociationVolume 7, Number 19 https://doi.org/10.1161/JAHA.118.009835 Amazon Links: *As An Amazon Associate I Earn A Small Commission From Qualifying Purchases At No Extra Cost To You*Pure Encapsulations Brand Mitochondria-Supporting Supplements:Magnesium Glycinate https://amzn.to/4iWlvhx Magnesium Citrate https://amzn.to/4ldRPy1 B complex Plus https://amzn.to/4lj1yTD B complex with PQQ and ALA https://amzn.to/4i3Kv54 CoQ 10 (active form Ubiquinol) https://amzn.to/4lisnHA Saccharomyces boulardii (probiotic) https://amzn.to/3DXc4zg Bellway Super Fiber: https://amzn.to/4i7Ud6B Nature's Sunshine Liquid Chlorophyll ES: https://amzn.to/42xQEly Epic Water Filter Products: https://amzn.to/42wOKSe Join the conversation: Share your thoughts with us on social media or in the comments!Subscribe, Share & Review: Remember to subscribe, share this episode, and leave a review. Your support helps us reach more women looking for answers.Disclaimer: Nothing in this podcast is to be taken as medical advice, please take informed accountability and speak to your provider before making changes to your health routine.The primary purpose of The Pretty Well Podcast being to educate. This content is for informational and educational purposes only. It is not intended to provide medical advice nor to take the place of such advice or treatment from a personal physician. By listening to this content, you agree to consult your own physician or qualified health professional regarding specific health questions. Neither Lisa Smith, The Pretty Well Podcast, nor any guest takes responsibility for possible health consequences of any person or persons following the information in this educational content. All listeners of this content, especially those who are pregnant or taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, or lifestyle program. The Pretty Well Podcast is for private non-commercial use and our guests do not necessarily reflect any agency, organization, or company that they work for. In addition, opinions of interview guests do not necessarily reflect the opinions of Lisa Smith and/or The Pretty Well Podcast. This content is not guaranteed to be correct, complete, or up to date.If you tune into any of the following shows, you'll like ours too! The Dr. Josh Axe Show, Wellness Mama, Be Well By Kelly Leveque, The Freely Rooted Podcast with Kori Meloy, The Dr. Mark Hyman Show, Dr. Jockers Functional Nutrition
Rewiring Your Vagus Nerve: A Functional ApproachWhile vagus nerve exercises like cold plunges and humming are popular, this episode explores a deeper functional perspective. What if underlying factors like mineral imbalances, gut issues, mold exposure, or structural misalignments are blocking your vagal function?The Mineral ConnectionYour vagus nerve functions as your body's electrical system, with minerals as crucial conductors. Hair Tissue Mineral Analysis reveals important patterns:- Calcium/Magnesium Ratio: Excessive calcium dominance keeps you stuck in "fight or flight"- Calcium/Phosphorus Ratio: Ideally balanced at 2.3:1 for optimal function- Potassium Levels: Low levels signal insufficient nerve energy- Heavy Metal Burden: Toxic metals hijack nerve function by stealing mineral binding sites"Your vagus nerve is your digestive system's power cord. Mineral imbalances create short circuits!"The Gut-Vagus ConnectionYour gut contains the second largest neural system after the brain. Comprehensive stool testing can identify issues affecting vagal function:- Low microbial diversity correlates with reduced vagal tone- Deficiencies in butyrate-producers deprive the nerve of energy- Dysbiosis creates inflammation that dampens signalingThis creates a feedback loop: poor vagal tone worsens digestive function, increasing dysbiosis, further impairing vagal tone.Mold ExposureMold illness disrupts vagus nerve function through:- Direct neurotoxicity to vagal nuclei- Mitochondrial damage impairing energy production- Inflammatory cascades that dampen vagal toneMany experience treatment resistance because underlying mycotoxin burden continues suppressing function.Structural ConsiderationsThe vagus nerve can physically get "pinched" due to:- Cranial misalignments- Neck tension- Rib cage restrictions- Abdominal compressionThis explains why bodywork sometimes dramatically improves digestion when supplements haven't helped.Practical Support StrategiesWhile addressing root causes, try:1. Singing: Creates vibrations that stimulate the vagus2. Essential Oils: Applied diluted behind the ears3. Digestive Bitters: Trigger vagal firing4. Omega-3 Fatty Acids: Provide building blocks for nerve structureThe Holistic ApproachRather than isolated "hacks," assess your unique terrain. When we restore harmony to the entire ecosystem, vagal tone naturally improves, with benefits cascading throughout your physiology.Looking for deeper support? Visit the "Work With Me" page on my website to learn about my approach to mineral balancing and microbiome optimization – two key pillars that profoundly affect vagus nerve function and overall health. Mineral Foundations Course HERE Learn more about how you can I can work together HERE Book an initial health session HERE Join my newsletter HERE If you are interested in becoming a client and have questions, reach out by emailing me: connect@lydiajoy.me Find me on Instagram : @ Lydiajoy.me OR @ holisticmineralbalancing
Think strong bones are just about calcium and vitamin D? Think again. Your bones are living, ever-changing structures influenced by far more than just minerals. Mitochondrial health, blood sugar balance, and even your gut microbiome all play important roles in bone remodeling. Understanding these connections can help you maintain strong, resilient bones for life. Read on to explore the science behind bone health and the key factors that keep your skeletal system strong.www.georgebatista.com
BUFFALO, NY — April 7, 2025 — A new #research paper was #published in Aging (Aging-US) on March 18, 2025, in Volume 17, Issue 3, titled “Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsiveness.” Researchers from the University of Arkansas for Medical Sciences, led by first author Ana Resende-Coelho and corresponding authors Melda Onal and Maria Almeida, investigated why bones become less responsive to exercise as people age. They studied two well-known aging-related cellular changes: oxidative stress (a buildup of harmful molecules inside cells) and reduced autophagy (a slowdown in the cell's ability to clean out and recycle damaged parts) to determine whether these could explain the decline in bone strength. Their findings revealed that these changes alone are not enough to account for the reduced bone-building response seen with aging. Physical activity is known to strengthen bones by creating mechanical stress, which activates bone cells like osteocytes to promote new bone formation. However, this process becomes less effective with age, increasing the risk of bone loss and fractures in older adults. The study aimed to uncover why this response weakens over time by focusing on specific age-related changes inside bone-forming cells. “The bone response to loading is less effective with aging, but the cellular and molecular mechanisms responsible for the impaired mechanoresponsiveness remain unclear.” The research team used a well-established mouse model in which pressure was applied to the tibia, simulating the effects of exercise. As expected, bones from older mice showed a weaker response compared to those of younger mice. However, when the researchers examined younger mice genetically modified to have either high oxidative stress or impaired autophagy, as seen in aging, their bones still responded normally to mechanical loading. The researchers also found that damage to the bone's osteocyte network, a system of cells that helps sense and respond to mechanical forces, did not prevent a healthy bone-building response in mice with autophagy deficiencies. This challenges the long-standing idea that deterioration of this cell network is a main cause of age-related bone decline. These results are significant because they eliminate two widely suspected causes of the aging skeleton's reduced responsiveness to exercise. While oxidative stress and autophagy dysfunction are common in older bone, they are not solely responsible for its reduced ability to grow stronger under physical stress. The authors suggest that future studies should explore other possible factors, such as changes in energy metabolism or how bone cells communicate. Overall, this study shows that bone aging is more complex than previously thought. Protecting bone health in older adults may require new strategies that go beyond targeting oxidative stress or autophagy. DOI - https://doi.org/10.18632/aging.206213 Corresponding authors - Melda Onal - MOnal@uams.edu, and Maria Almeida - schullermaria@uams.edu Video short - https://www.youtube.com/watch?v=fHQhA6rOaDc Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206213 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, Atg7, tibia compressive loading, Sod2, Osx1-Cre, osteocytes Please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
Story at-a-glance Mitochondrial dysfunction is a key driver of neurodegeneration, with research showing that a single resting cortical neuron requires 4.7 billion ATP molecules every second for energy When mitochondria lose their efficient shape, electrons escape and form reactive oxygen species (ROS), triggering cellular damage and stress that particularly affects brain cells Research shows 42% of adults over 55 develop dementia by age 95, with projected new cases expected to double from 514,000 in 2020 to 1 million by 2060 Mitochondria act as cellular calcium buffers — when this function fails, calcium floods cells and triggers the mitochondrial permeability transition pore, leading to widespread neuron death Key mitochondrial health strategies include eliminating seed oils, optimizing carbohydrate intake, reducing environmental toxin exposure, getting proper sun exposure and boosting NAD⁺ levels through supplements
What if everything we thought we knew about fat is wrong—and one molecule could change how we age, heal, and live? In this cutting-edge episode of SuperLife with Darin Olien, Darin is joined by Dr. Stephanie Venn-Watson, a veterinary epidemiologist, former Navy scientist, and co-founder of Fatty15. Together, they unpack the discovery of C15:0, the first essential fatty acid identified in 90 years, and the tidal wave of science supporting its impact on longevity, inflammation, metabolic health, and cellular survival. From accidental dolphin data to peer-reviewed clinical trials, Dr. Steph reveals how C15 could become one of the most important health breakthroughs of our time. What You'll Learn in This Episode: (00:00:00) Introduction – What today's episode is all about (00:04:15) Meet Dr. Stephanie Venn-Watson – Her origin story and the accidental discovery of C15 (00:07:45) What is C15 and how is it different from omega-3s and saturated fats? (00:12:02) Why the USDA once told us to avoid fats—and how that caused unintended harm (00:16:30) The Navy's dolphin program & the surprising longevity connection (00:20:12) The essential fatty acid problem – Why C15 is needed in modern diets (00:24:45) C15 and inflammation – How this fat helps regulate immune response (00:29:40) What clinical trials are showing – Type 2 diabetes, liver disease, and more (00:34:01) Why our food system lost C15 – Industrial changes to dairy and livestock (00:38:25) The mitochondria connection – How C15 supports energy and cellular repair (00:43:10) Ferroptosis and cellular death – The antioxidant role of C15 (00:47:50) What “essential” really means – Revisiting the 1930s nutrient criteria (00:52:15) Real-world use cases: pets, children, elders, and chronic illness (00:56:40) Gut microbiome and metabolic syndrome – The C15 balancing effect (01:00:55) Saturated fat confusion – Not all fats are created equal (01:05:00) The science of “good fat” – What makes C15 fundamentally different (01:09:45) Global research momentum – Who's funding and validating the studies (01:14:05) The future of C15 in agriculture, food, and longevity medicine (01:18:45) What Dr. Steph wishes every doctor and nutritionist knew (01:22:35) Practical ways to start – How to safely integrate C15 into your life (01:28:10) Final thoughts – What happens when we redefine “essential” Topics Covered: Discovery of C15:0 Essential fatty acids Dolphin research & human longevity Chronic inflammation, insulin resistance, liver disease Cellular death & ferroptosis Gut microbiome & metabolism Mitochondrial repair & oxidative stress Nutritional science and real-world application Don't Forget... I just launched my brand new program Superlife Supermind. Visit my website https://superlife.com/ to learn more about how you can get rid of stress, improve sleep and overall health today. Thank You to Our Sponsors: Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order. Shakeology: Premium whole-food nutrition shake for energy, immunity, gut health, and longevity. Get 15% off, free shipping, and a free shaker cup at Shakeology.com with code SUPERLIFE Find More From Dr. Stephanie Venn-Watson: Website: fatty15.com Instagram: @fatty15 Book: The Longevity Nutrient (available now) Find More From Darin: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Key Takeaway: "C15 isn't just a supplement—it's a paradigm shift in what we define as essential nutrition." – Dr. Stephanie Venn-Watson
Every so often people reach out to me and request that I cover a particular topic, relative to our favorite subjects on this podcast. So today we are going to take a deep dive into some of those topics that were requested by some of your fellow TRLR listeners. The first topic is red light therapy (RLT) for tendinopathy (i.e. pain from overuse in tendons), where I discuss the mechanisms of how RLT has the potential to help heal this type of an injury, review the most relevant research and then provide some practical application for what a real treatment would look like with a RLT devce.The second topic is how to apply The Mitochondrial Triad for fertility. I first examine the role that mitochondrial dysfunction plays in facilitating low fertility rates and then scrutinize how/why RLT, methylene blue and C60 may have efficacious, profound potential for improving and optimizing fertility — both from the female and male perspective. I also offer some practical application for each aspect of The Mitochondrial for women and men. If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: (00:00) - The Red Light Report intro with Dr. Mike Belkowski. (00:16) - BioLight at the Health Optimization Summit; possible new product reveal. (02:49) - BioLight expanding into a Times Square retail space. (03:20) - Red light therapy for tendinopathy: reduces pain, inflammation, and boosts collagen. (06:42) - Near-infrared light aids deep tendon healing; best for surface tendons like the Achilles. (15:22) - Eccentric exercises + red light therapy improve recovery. (20:13) - Suggested dosage: 5-7 J/cm² for tendinopathy. (30:13) - Mitochondrial function is crucial for fertility in men and women. (39:02) - Red light therapy supports female fertility, PCOS, and endometriosis. (43:24) - Red light therapy boosts sperm motility and testosterone. (45:43) - Methylene blue and C60 enhance mitochondrial function and protect reproductive health. (55:26) - The mitochondrial triad (red light therapy, methylene blue, C60) optimizes fertility. (59:47) - Mitochondria are key to overall health—use light therapy wisely. - Upcoming BioLight Events: Health Optimisation Summit (Biohacking Conference), April 12 - 13 (Austin, TX) Returning to Nature (Quantum Health Retreat), June 26 - 27 (Franklin, TN) - Articles referenced in episode: The effect of low-level red and near-infrared photobiomodulation on pain and function in tendinopathy: a systematic review and meta-analysis of randomized control trials Photobiomodulation for Tendinopathy: A Review of Preclinical Studies Photobiomodulation effects on Achilles tendon pain: a systematic review and meta-analysis of randomized clinical trials Photobiomodulation and eccentric exercise for Achilles tendinopathy: a randomized controlled trial Analysis of pain relief and functional recovery in patients with shoulder tendinopathy treated with therapeutic ultrasound combined with LED photobiomodulation therapy - Save 25% when you Subscribe & Save to a BioBundle! For a BioBundle, you choose:1.) Any one BioBlue supplement(BioBlue, BioBlue (SR), BioBlue Leuco, BioBlue Calm, BioBlue Capsules or BioBlue Leuco Capsules)2.) Any one BioC60 supplement(Regular or Concentrated) The BioBundle automatically saves you 15% on both of the supplements you choose.You save an additional 10% by choosing to Subscribe & Save to that BioBundle.The 25% savings is passed along for every monthly delivery of your BioBundle!No discount code necessary! Click here to check out The BioBundle - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn BioLight: Website Instagram YouTube Facebook
Could a simple blue dye be the key to boosting your immune system and healing your mitochondria?
Story at-a-glance Suppression of mitochondrial ATP production prevents apoptosis and activates the NLRP3 inflammasome, a key player in inflammation and disease Inhibitors of oxidative phosphorylation (OXPHOS) lead to changes in mitochondrial cristae structure and retention of cytochrome c, which is necessary for NLRP3 activation but not sufficient on its own Activation of the NLRP3 inflammasome requires two signals, one of which is mitochondrial, highlighting the complexity of its regulation Diverse NLRP3 activators share the ability to suppress apoptosis, allowing damaged cells to survive and contributing to chronic inflammation and cancer Mitochondrial dysfunction is closely linked to inflammation and various diseases, emphasizing the importance of understanding these mechanisms for optimal health
In this episode, Dr. Nasha Winters shares her powerful journey with cancer and the urgent need for a paradigm shift in oncology. She explores the limitations of the current cancer care model, the critical role of mitochondria in chronic illness, and why asking different questions is essential for improving patient outcomes. Dr. Winters also introduces MTOMICS, a cutting-edge data platform designed to revolutionize cancer treatment by integrating personalized, data-driven insights. Listen to the full episode to learn more: The standard cancer care model has seen little progress in outcomes since 1971. Cancer is affecting younger populations, signaling the need for new approaches. Mitochondrial health is a cornerstone of cancer and chronic disease management. Integrative medicine offers evidence-based strategies to enhance patient care. Community and collaboration are essential for driving meaningful change. Data-driven, decentralized healthcare models can empower both patients and practitioners. And much more! Tune in to discover how integrative oncology, cutting-edge research, and patient empowerment are reshaping the future of cancer care.
Mitochondria are the powerhouse of the cell, but their role in longevity and overall health goes far beyond energy production. When mitochondrial function declines, it contributes to aging, inflammation, and chronic disease. In this episode, I am excited to welcome back Dr. Elizabeth Yurth to break down why mitochondria are at the root of longevity, how to optimize mitochondrial function, and the best peptides, supplements, and lifestyle strategies to support cellular health.Dr. Elizabeth Yurth, MD, is a board-certified specialist in longevity, regenerative medicine, and orthopedics, as well as the co-founder and medical director of the Boulder Longevity Institute. She's a leading expert in peptide therapy, cellular medicine, and age-related disease prevention.- Intro (00:00 - 00:57)- Dr. Elizabeth Yurth's recent work in cellular medicine (00:57 - 04:34)- Why mitochondria are essential for energy and longevity (04:34 - 07:05)- Mitochondria and hormone production: The overlooked connection (07:05 - 08:20)- Mitochondrial dysfunction: The root cause of chronic disease (08:20 - 11:24)- How mitochondrial dysfunction leads to inflammation & oxidative stress (11:24 - 17:33)- Top signs & symptoms of mitochondrial dysfunction (17:33 - 24:31)- Environmental factors that damage mitochondria (toxins, stress, diet, etc.) (24:31 - 31:31)- Can we test for mitochondrial health? Biomarkers & lab tests (31:31 - 39:00)- How lifestyle impacts mitochondria: Fasting, exercise, red light therapy (39:00 - 45:15)- Best supplements for mitochondria: NAD, CoQ10, 1-MNA, creatine - and are NAD precursors like NMN & NR actually beneficial? (45:15 - 48:39)- Ketones & creatine: The ultimate mitochondrial enhancers (48:39 - 55:33)- Mitochondrial peptides: SS-31, Humanin, 5-Amino-1MQ & more (55:33 - 01:01:56)- How SS-31 repairs mitochondrial membranes & boosts energy (01:01:56 - 01:09:53)- The future of mitochondrial medicine: Mitochondrial uncouplers & new peptides (01:09:53 - 01:14:48)- Dr. Yurth's biggest lesson on longevity & cellular medicine (01:14:48 - 01:18:08)- Where to find Dr. Yurth & learn more about mitochondrial health (01:18:08 - 01:18:30)
I thoroughly enjoy taking deep dives with experts in the realm of quantum and circadian biology. It's one of the few times I get to truly geek out on some of the nuances of mitochondria and how light, water and magnetism impacts our wellness and longevity. Today's guest, Oksana Hansen, ticks all of those boxes and then some, as she has quite the origin story and health journey that led her to becoming a quantum and circadian health expert and, ultimately, a quantum clinician. So not only can she speak from didactic knowledge, but she can also pull from her experience treating clients.Oksana's personal health challenges, including a cancer diagnosis, led her to become an advocate for her own health. This experience propelled her into extensive research, focusing on understanding the root causes of health issues rather than merely addressing symptoms. Her exploration into quantum and circadian biology highlighted the significance of aligning with natural biological rhythms for overall well-being.In addition to her role at Quantum Lens Wellness, Oksana hosts the “Quantum Lens Podcast,” where she discusses topics related to quantum biology, circadian rhythms, and holistic health practices.Through her work, Oksana Hansen continues to inspire and guide individuals towards achieving optimal health by harmonizing with the natural elements of light, water, and magnetism. If you found the information in today's episode with Oksana Hansen particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Watch this video on YouTube - Return to Nature Retreat (June 26th & 27th) — hosted by Oksana Hansen & Carrie Bennett - Where to learn more from and about Oksana Hansen: Quantum Lens Wellness website Instagram Facebook Quantum Lens Podcast - Key Points [1:30] Oksana's background in quantum biology & the upcoming June conference [4:00] Oksana's personal health journey: From corporate executive to health crisis [9:00] The problems with conventional blood work analysis & medical diagnosis [12:30] Melanoma diagnosis, questioning mainstream sun exposure advice [15:00] The role of sunscreen toxicity & oxybenzone recall in skin health [18:00] The transition into quantum biology: Light, water, mitochondria & healing [21:00] Hydration & Mitochondria Can we hydrate without drinking water by improving mitochondrial function? [24:00] Ways to Acquire Electrons for Health Importance of circadian rhythm and the body's natural clock. [26:30] Light, Flicker, and Its Effect on Health Sunlight vs. artificial lighting and how it impacts circadian rhythm. [30:00] Seasonal Sunlight, Vitamin D, & Circadian Biology Does moving between sunny climates disrupt human biology? [33:00] Blue Light Blocking & Flicker Reduction Tools Can similar flicker reduction tools be developed for larger screens? [36:00] Return to Nature Conference Overview Location, event structure, and VIP experiences. [40:00] Importance of mastering thoughts when facing health challenges. [45:00] Overcoming Stubborn Mindsets [48:00] Revisiting Core Wellness Pillars Microbes in nature and their role in immunity. [50:30] Magnetism & Sleep Aids Discussion on magnetic mattress pads and their legitimacy. [54:00] The Quantum Keto Diet [57:30] Final Thoughts & Meditation Practices [1:00:00] The Importance of Slowing Down and Returning to Nature [1:00:30] Practitioner Perspective: Anecdotes from Quantum Biology [1:01:08] Case Study: Overcoming Infertility Through Natural Practices [1:01:45] Simple Biological Adjustments for Fertility [1:02:16] The Simplicity of Quantum Biology [1:02:48] Comparing Quantum Biology with Conventional Medicine [1:03:13] Overcoming Skepticism About Simple Health Solutions [1:03:47] Mindset Shifts and Fear in Medical Perception [1:04:15] Final Thoughts on Quantum Biology and Natural Healing - Save 25% when you Subscribe & Save to a BioBundle!For a BioBundle, you choose: 1.) Any one BioBlue supplement(BioBlue, BioBlue (SR), BioBlue Leuco, BioBlue Calm, BioBlue Capsules or BioBlue Leuco Capsules)2.) Any one BioC60 supplement (Regular or Concentrated) The BioBundle automatically saves you 15% on both of the supplements you choose. You save an additional 10% by choosing to Subscribe & Save to that BioBundle. The 25% savings is passed along for every monthly delivery of your BioBundle! No discount code necessary! To shop the BioBundle, click here! - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn BioLight: Website Instagram YouTube Facebook
What if everything you've been taught about healing is backward? In this eye-opening exploration of fundamental biological principles, we challenge the conventional wisdom that positions us as fixers of a broken system, revealing instead the extraordinary intelligence already at work within you.Your body isn't a static object but a dynamic process—with 37 sextillion chemical reactions happening every second and millions of new cells being created, it operates with a complexity beyond human comprehension. This isn't just fascinating trivia; it's the key to understanding why true healing occurs not when we intervene, but when we create the environment for your body's innate wisdom to flourish.We dive deep into the mitochondrial connection to longevity, explaining how these cellular powerhouses determine health across all mammal species. The strength of mitochondrial membranes directly correlates with lifespan—stronger membranes mean longer lives. Through practical strategies like strategic exercise, proper sleep rhythms, intermittent fasting, and cold exposure, you'll learn how to upregulate PGC1-alpha, the master controller of mitochondrial production.The conversation challenges popular misconceptions about essential fatty acids, hormone therapies, and chronic conditions. Rather than seeing symptoms as isolated problems requiring separate treatments, we reveal how seemingly different health challenges often stem from the same underlying imbalances. When you restore proper biological balance by eliminating toxins, optimizing nutrition, and supporting natural processes, your body can resolve multiple issues simultaneously.Whether you're dealing with digestive issues, hormonal imbalances, chronic inflammation, or more serious health challenges, this episode provides a framework for understanding health that transcSend us a text Join Dr. Lodi's Inner Circle membership and unlock exclusive access to webinars, healthy recipes, e-books, educational videos, live Zoom Q&A sessions with Dr. Lodi, plus fresh content every month. Elevate your healing journey today by visiting drlodi.com and use the coupon code podcast (all lowercase: P-O-D-C-A-S-T) for 30% off your first month on any membership option. Support the showThis episode features answers to health and cancer-related questions from Dr. Lodi's social media livestream on Jan. 19th, 2025Join Dr. Lodi's FREE Q&A livestreams every Sunday on Facebook, Instagram, and Tiktok (@drthomaslodi) and listen to the replays here.Submit your question for next Sunday's Q&A Livestream here:https://drlodi.com/live/Facebookhttps://www.facebook.com/DrThomasLodi/Instagramhttps://www.instagram.com/drthomaslodi/ Join Dr. Lodi's Inner Circle membership and unlock exclusive access to webinars, healthy recipes, e-books, educational videos, live Zoom Q&A sessions with Dr. Lodi, plus fresh content every month. Elevate your healing journey today by visiting drlodi.com and use the coupon code podcast (all lowercase: P-O-D-C-A-S-T) for 30% off your first month on any membership option. Learn to Thrive with ADHD Podcast Welcome to the Learn to Thrive with ADHD Podcast. This is the show for you if you're... Listen on: Apple Podcasts Spotify Join Dr. Lodi's informative FREE Livestreams...
Mitochondria do more than power our cells—they may hold the key to understanding and treating mental illness.In this episode of The Metabolic Link, Dr. Dominic D'Agostino sits down with Dr. Ana Andreazza, a leading expert in mitochondrial health at the University of Toronto.Dr. Andreazza has pioneered research linking mitochondrial dysfunction to psychiatric disorders like bipolar disorder, utilizing groundbreaking 3D brain organoid models to study neurotransmission. She also leads research on mitochondrial transplantation, a potential game-changer in regenerative medicine.Join us as we explore how mitochondria influence mood, metabolism, and overall health—and why optimizing mitochondrial function may be the future of medicine. Listen to the episode on any major podcast player or watch the interview on YouTube.Learn more about Dr. Andreazza's work here.Special thanks to our sponsors:Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK hereFatty15: Get 15% off their 90-day subscription Starter Kit with the code METABOLICLINK hereMUD/WTR: Start your new morning ritual & get up to 43% off your MUDWTR with code METABOLICLINK herePuori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Visit this link and use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
“Good stressors are the most powerful medicine we have,” explains Sharon Horesh Bergquist, M.D. Bergquist, an award-winning physician, innovative healthcare leader, and researcher, joins us today to explain why stress is actually a good thing, how to optimize our exercise routines, plus so much more: - The difference between good & bad stress (~2:20) - Exercise as a stressor (~3:15) - Zone 2 & HIIT (~4:45) - The 80/20 rule (~6:20) - Vigorous exercise (~11:10) - The power of intervals (~13:40) - Mitochondrial health (~15:00) - The balance between too much & not enough stress (~21:15) - The benefits of plant toxins (~24:28) - Hot/cold therapy (~30:10) - Temp & timing for cold exposure (~34:50) - Heat exposure (~43:10) - Temp & timing for heat exposure (~46:40) - Gender differences in stress exposure (~48:50) - Circadian fasting (~51:00) - Impactful takeaways (~54:45) - How to instill growth mindset in younger generations (~56:05) Referenced in the episode: - Follow Bergquist on Instagram (@thegoodstressdoctor) - Check out her website (https://drsharonbergquist.com/) - Pick up her book, The Stress Paradox - Research on vigorous intermittent lifestyle physical activity (https://doi.org/10.1038/s41591-022-02100-x) - Research on interval-walking training (DOI: 10.23736/S0022-4707.22.14263-5) - Global Burden of Disease Study (DOI: 10.1016/S0140-6736(18)32279-7) - Research on stress & biological age (https://link.springer.com/article/10.1007/s10522-022-09985-8) Go to get.stash.com/mindbodygreen to see how you can receive $25 towards your first stock purchase and to view important disclosures We hope you enjoy this episode, and feel free to watch the full video on YouTube! Whether it's an article or podcast, we want to know what we can do to help here at mindbodygreen. Let us know at: podcast@mindbodygreen.com. Learn more about your ad choices. Visit megaphone.fm/adchoices
Watch Here : https://www.youtube.com/watch?v=CnIJbbCvFdQ Website: https://vigoroussteve.com/ Consultations: https://vigoroussteve.com/consultations/ eBooks: https://vigoroussteve.com/shop/ YouTube Channel: http://www.youtube.com/user/VigorousSteve/ Workout Clips Channel: https://www.youtube.com/channel/UCWi2zZJwmQ6Mqg92FW2JbiA Instagram: https://instagram.com/vigoroussteve/ TikTok: https://www.tiktok.com/@vigoroussteve Reddit: https://www.reddit.com/r/VigorousSteve/ PodBean: https://vigoroussteve.podbean.com/ Spotify: https://open.spotify.com/show/2wR0XWY00qLq9K7tlvJ000 Patreon: https://www.patreon.com/vigoroussteve
In Episode 144 of the Fit Mother Project Podcast, Dr. Anurag Singh, MD, PhD, and Chief Medical Officer of Timeline, discusses the critical role of mitochondria in energy production and their decline during aging with Dr. Anthony Balduzzi. Dr. Singh emphasizes the importance of mitochondrial health for longevity and introduces us to Urolithin A, a compound that can enhance mitochondrial function. Various strategies for improving mitochondrial health, including lifestyle interventions and supplementation are discussed in this podcast.Dr. Singh shares insights from clinical studies on Urolithin A and its potential benefits for both sedentary individuals and athletes. The conversation concludes with practical advice for maintaining cellular health and promoting longevity.Key TakeawaysMitochondria are essential for energy production in cells.Aging leads to mitochondrial dysfunction, impacting overall health.Lifestyle interventions like exercise and caloric restriction are crucial for mitochondrial health.Urolithin A is a powerful compound that supports mitochondrial function.Not everyone can produce Urolithin A from dietary sources.Mitochondrial health is linked to chronic inflammation and aging.Clinical studies show Urolithin A improves muscle strength and endurance.Recovery from exercise can be enhanced with Urolithin A supplementation.Longevity requires a holistic approach to health and wellness.Maintaining cellular health is foundational for overall well-being.More About Dr. Anurag Singh, MD, PhD and TimelineWebsite: http://timeline.com/fitfatherprojectUse code FITFATHERPROJECT at checkout for 10% off your order.Instagram: https://www.instagram.com/timeline_longevity/Facebook: https://www.facebook.com/TimelineLongevityYouTube: https://www.youtube.com/channel/UCLrzBI9lZwDhYA4ifWh2vZwTikTok: https://www.tiktok.com/@timelinelongevityBiographical Information on Dr. Anurag Singh, MD, PhDAnurag Singh is currently Chief Medical Officer at Timeline, developing next-generation advanced nutritional and skincare products targeting improvements in mitochondrial and cellular health. With an M.D. in internal medicine and a Ph.D. in immunology, his experience includes work at top consumer health (Nestlé, Nestlé Health Science) and startup companies (Amazentis/Timeline). He's authored over 40 articles for top science journals, been awarded over 15 patents, and has designed and led over 50 randomized clinical trials. Over the past decade, his research across multiple clinical trials on the postbiotic Urolithin A and its health benefits has led to the launch of multiple consumer products.Want To Change Your Life? Check Out Foundations!Foundations is a simple, sustainable, and specific weight loss program designed especially for busy women over 40. With short metabolic training workouts, an easy-to-follow meal plan, and an accountability team there for you every step of the way, Foundations can help you lose weight, regain energy and vitality, and live life to the fullest.
In Episode 231 of the Fit Father Project Podcast, Dr. Anurag Singh, MD, PhD, and CEO of Timeline, discusses the critical role of mitochondria in energy production and their decline during aging with Dr. Anthony Balduzzi. Dr. Singh emphasizes the importance of mitochondrial health for longevity and introduces us to Urolithin A, a compound that can enhance mitochondrial function. Various strategies for improving mitochondrial health, including lifestyle interventions and supplementation are discussed in this podcast.Dr. Singh shares insights from clinical studies on Urolithin A and its potential benefits for both sedentary individuals and athletes. The conversation concludes with practical advice for maintaining cellular health and promoting longevity.Key TakeawaysMitochondria are essential for energy production in cells.Aging leads to mitochondrial dysfunction, impacting overall health.Lifestyle interventions like exercise and caloric restriction are crucial for mitochondrial health.Urolithin A is a powerful compound that supports mitochondrial function.Not everyone can produce Urolithin A from dietary sources.Mitochondrial health is linked to chronic inflammation and aging.Clinical studies show Urolithin A improves muscle strength and endurance.Recovery from exercise can be enhanced with Urolithin A supplementation.Longevity requires a holistic approach to health and wellness.Maintaining cellular health is foundational for overall well-being.More About Dr. Anurag Singh, MD, PhD and TimelineWebsite: http://timeline.com/fitfatherprojectUse code FITFATHERPROJECT at checkout for 10% off your order.Instagram: https://www.instagram.com/timeline_longevity/Facebook: https://www.facebook.com/TimelineLongevityYouTube: https://www.youtube.com/channel/UCLrzBI9lZwDhYA4ifWh2vZwTikTok: https://www.tiktok.com/@timelinelongevityBiographical Information on Dr. Anurag Singh, MD, PhDAnurag Singh is currently Chief Medical Officer at Timeline, developing next-generation advanced nutritional and skincare products targeting improvements in mitochondrial and cellular health. With an M.D. in internal medicine and a Ph.D. in immunology, his experience includes work at top consumer health (Nestlé, Nestlé Health Science) and startup companies (Amazentis/Timeline). He's authored over 40 articles for top science journals, been awarded over 15 patents, and has designed and led over 50 randomized clinical trials. Over the past decade, his research across multiple clinical trials on the postbiotic Urolithin A and its health benefits has led to the launch of multiple consumer products.Want To Change Your Life? Check Out Foundations!Foundations is a simple, sustainable, and specific weight loss program designed especially for busy men over 40. With short metabolic training workouts, an easy-to-follow meal plan, and an accountability team there for you every step of the way, Foundations can help you lose weight, regain energy and vitality, and live life to the fullest. Click here to see everything you get when you join Foundations, subscribe to our
Muscle Minds Podcast Dr Scott Stevenson & Scott McNally 0:00 SLU-PP-332 6:00 Understanding Mitochondrial Biogenesis 15:00 Intro 17:00 How do esters break down 24:00 Researching PEDs 29:00 The Best Role Models 36:00 Hitting Depth on Hacks without pain 41:00 Is SHBG a bad thing? Role of SHBG 45:00 Caber - Is it dangerous 53:40 Glycogen holding water 1:02:35 Growing Rear Delts ✅ Signed Copy of Be Your Own Bodybuilding Coach (15% goes to ASPCA) https://www.ebay.com/itm/205121965946
In this conversation, Dr. Mike Van Thielen discusses the benefits and mechanisms of molecular hydrogen as a powerful biohacking tool for health optimization. He explains how hydrogen acts as a selective antioxidant, promotes cellular health, and supports mitochondrial function. The discussion also covers practical applications, including different methods of hydrogen delivery and the importance of integrating hydrogen therapy with other health practices for optimal results. Takeaways ✅ Molecular hydrogen has positive effects on over 170 diseases. ✅ It acts as a selective antioxidant, neutralizing harmful free radicals. ✅ Hydrogen promotes autophagy, recycling damaged cellular components. ✅ Mitochondrial health is crucial for overall energy production and longevity. ✅ Hydrogen can easily cross the blood-brain barrier, benefiting neurological health. ✅ There are no shortcuts to health; a holistic approach is necessary. ✅ Hydrogen therapy is 100% safe and can be used alongside other treatments. ✅ Avoiding electromagnetic radiation is important for cellular health. ✅ Not all PMF devices are effective; analog devices are preferred. Chapters 00:00 Introduction to Molecular Hydrogen and Biohacking 11:21 Understanding the Mechanisms of Molecular Hydrogen 22:50 Practical Applications and Devices for Hydrogen Therapy 33:08 Integrating Hydrogen Therapy with Other Health Practices
Join Dr. David Jockers and his guest, Ari Whitten, as they explore the cell danger response, revealing how this protective mechanism helps manage stress and promote healing. Gain insights into its role in disease prevention and overall health maintenance. Delve into the vital functions of mitochondria, discussing their key role in cellular health, aging, and resilience. Understand how maintaining mitochondrial health is crucial for combating chronic illness and enhancing longevity. Explore the concept of hormesis, uncovering how controlled stress can boost cellular strength and wellness. Discover actionable strategies to apply hormesis in daily life, fostering a robust defense system for the body. In This Episode: 00:00 Introduction to Stress and Adaptation 02:02 Introducing Ari Witten and the Cell Danger Response 04:10 Understanding the Cell Danger Response 15:23 Factors Keeping Us in the Cell Danger Response 17:56 The Allostatic Load and Homeodynamic Space Models 30:50 Mitochondrial Health and Aging 35:26 The Importance of Mitochondrial Quality 41:54 Hormetic Stressors and Building Resilience 52:08 Conclusion and Final Thoughts Struggling with low energy, frequent colds, or dull skin? Vitamin C is essential for boosting your immune system and revitalizing skin health. Paleo Valley's Essential C Complex, made from potent whole food sources, ensures you get these benefits naturally, without synthetic additives. Enjoy a special 15% discount on your first order of Paleo Valley's Essential C Complex by visiting PaleoValley.com/Jockers. Harness the power of nature with this whole food supplement to support your health effectively. Kick off the new year by supercharging your gut health with Just Thrive Probiotic! Unlike ordinary probiotics that perish before they even reach your gut, Just Thrive's revolutionary formula is clinically proven to arrive 100% alive. This ensures optimal digestive health, robust immunity, and vibrant energy—essential components for anyone aiming to conquer their wellness goals this year. Perfect for supporting effortless weight management, Just Thrive Probiotic is your go-to for a healthier lifestyle. Don't wait to start feeling your best—head over to justthrivehealth.com and use code Jockers to snag a 20% discount on your first purchase. Here's to a healthier, happier you with Just Thrive! Unlock the secrets of your body's unique nutritional needs with Genova Connect's Metabolomix Plus, an easy at-home test that dives deep into your metabolism. This comprehensive assessment reveals critical insights into your amino acids, vitamins, antioxidants, and fatty acids levels, guiding you to optimize your diet and supplements with precision. Ready to revolutionize your health? Visit GenovaConnect.com to discover how you can fine-tune your nutrition for peak performance and vitality "The cell danger response is essentially your body's way of protecting itself at a cellular level, shifting resources to defense instead of growth and repair." - Ari Whitten Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Visit justthrivehealth.com and use code Jockers for a 20% discount Paleovalley - visit paleovalley.com/jockers Visit GenovaConnect.com Connect with Ari Whitten: Email: affiliates@theenergyblueprint.com Website: https://theenergyblueprint.com/ Eat For Energy Book: https://amzn.to/3vByaQn Red Light Therapy Book: https://amzn.to/3vFqlZV Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
In episode 280 of The Super Human Life, Coach Frank Rich and Jay Campbell delve into the importance of hormonal optimization for muscle growth and cognitive function, particularly focusing on the role of peptides and Metformin. They discuss the necessity of understanding hormonal deficiencies before starting peptide therapy, the significance of Metformin in regulating blood sugar and its effects on muscle building, and the lifestyle changes needed to support hormonal health. The conversation also explores various peptides, including growth hormone agonists and mitochondrial optimizing peptides, and their applications in enhancing physical performance and overall health. They discuss the efficacy of specific supplements, the significance of biomarkers, and the impact of structured training on overall life goals. Coach Frank & Jay explore the role of GLP-1 in behavioral changes and its implications for health and addiction recovery. The discussion also touches on the future of health and medicine, particularly in relation to peptides and their safety, emphasizing the need for responsible usage and education in the biohacking community. Takeaways Peptides are effective only when hormonal levels are optimized. Metformin helps regulate blood sugar and supports muscle growth. Therapeutic testosterone is crucial for men over 30. Mitochondrial health is essential for energy production. Cycling peptides is necessary to prevent receptor saturation. Lifestyle changes can significantly impact hormonal health. Consult with knowledgeable physicians for hormone optimization. Supplements can significantly enhance force production and overall performance. Sustainability of gains from peptides depends on overall lifestyle choices. Young men should prioritize strength training and hormone monitoring. Making the gym a priority can lead to broader life improvements. A clear fitness goal transforms exercise into a purposeful training regimen. Clearly defined end-stage goals are essential for success. GLP-1 drugs can significantly alter behavior and health outcomes. The future of medicine may shift towards biohacking and peptides. Jay Campbell is a 5x international best-selling author, men's physique champion, and the Owner and Co-Founder of BioLongevity Labs. Widely recognized as a leading expert on hormonal optimization, therapeutic peptides, and biohacking for health and performance, Jay is on a mission to help individuals break free from the failing "sick care" system and take control of their health. Jay's journey began after a sports injury forced him to rethink traditional approaches to health. Through years of intense research and personal experience, he uncovered the power of therapeutic testosterone and peptides - two game-changing tools that transformed his own life and health. As the founder of BioLongevity Labs, Jay is at the forefront of a revolution, bringing cutting-edge peptides and bioregulators to the world to address cellular regeneration, hormonal balance, and metabolic health. Jay's mission is clear: to inspire and empower others to optimize their health, reverse aging, and unlock their true potential—physically, mentally, and emotionally. Connect with Jay: IG - https://www.instagram.com/jaycampbell333/ Website - https://jaycampbell.com/ Peptides - https://biolongevitylabs.com/ --- Connect with Frank and The Super Human Life on Social Media: Instagram: https://www.instagram.com/coachfrankrich/ Facebook: https://www.facebook.com/groups/584284948647477/ Website: http://www.thesuperhumanlifepodcast.com/tshlhome YouTube: https://www.youtube.com/channel/UCjB4UrpxtNO2AFtDURMzoKQ
In today's episode, I'm sitting down with Josh and Jeanne to talk about a big shift they've made over the past 20 years in how they approach healing. Too often, practitioners jump straight into blood tests before even discussing your lifestyle, but we're going to explore why that might be missing a critical piece of the puzzle. Josh and Jeannie share how they now prioritize understanding their clients as a whole person, and how this approach influences the health plans they create. We also dive into the importance of lifestyle, quantum health, and circadian rhythms—and why lab results aren't always the first thing you should look at when trying to improve your health. Timestamps: 00:00:00 - Introduction 00:03:57 - Quantum health and other methodologies 00:07:51 - Mitochondrial health + Root cause 00:11:17 - Wearables and stress levels 00:13:44 - Adapting to the new season of life 00:14:30 - Recurring illness + Victim mentality 00:17:32 - From healing to living 00:18:02 - Misunderstanding stress 00:19:11 - Leptin resistance and keto 00:20:22 - Psychoneuroimmunology (PNI) 00:23:50 - Less is more health protocols 00:26:24 - Nervous system and somatic health 00:29:17 - Getting rid of perfectionism 00:32:31 - Most common health issues 00:36:47 - Most clients are overwhelmed 00:38:21 - Extreme diets and protocols 00:43:19 - Exercise vs movement 00:47:15 - Lifestyle and nutrition coaching 00:49:35 - Lab testing 00:51:25 - Self-regulation 00:52:42 - HRT and aging 00:56:46 - Cortisol, progesterone, and steroids 00:59:27 - Overdosing on thyroid medication 01:01:55 - Struggling to lose weight 01:05:20 - Where to find Josh and Jeannie Sponsored By: Viva Rays Go to vivarays.com & use code: YOGI to save 15% Bon Charge Click here & use code for SARAHKLEINER for 15% off storewide. Black Lotus Shilajit Visit: www.blacklotusshilajit.com and Use Code: SARAHK for 15% the entire site! Check Out Josh and Jeanne: Website Instagram This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional! ________________________________________ Get all my free guides and product recommendations to get started on your journey! https://www.sarahkleinerwellness.com/all-free-resources Check out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) - https://www.sarahkleinerwellness.com/courses Sign up for my newsletter to get special offers in the future! -https://www.sarahkleinerwellness.com/contact Free Guide to Building your perfect quantum day (start here) - https://www.sarahkleinerwellness.com/opt-in-9d5f6918-77a8-40d7-bedf-93ca2ec8387f My free product guide with all product recommendations and discount codes: https://www.sarahkleinerwellness.com/resource_redirect/downloads/file-uploads/sites/2147573344/themes/2150788813/downloads/84c82fa-f201-42eb-5466-0524b41f6b18_2024_SKW_Affiliate_Guide_1_.pdf My Circadian App - Apple My Circadian App - Android My Circadian App - Youtube
Dave Watumull, CEO of AX3 Life, discusses the incredible health benefits of astaxanthin, a marine super nutrient with powerful effects on longevity and inflammation. From combating cellular aging to supporting brain and skin health, Dave shares 25 years of research and insights on how this nutrient can transform your well-being. Learn how astaxanthin works, its unique impact on inflammation modulation, and how it compares to other nutrients. OUR GUEST Dave Watumull is on a mission to bring astaxanthin to the world. This marine super nutrient supports whole body health and longevity and has captured his imagination for more than 25 years of research, development, and commercialization. He is the Co-Founder and CEO of AX3 Life, a consumer health company dedicated to astaxanthin products, education, and community. He is also the COO of Cardax, a life sciences business focused on pharmaceutical and nutraceutical applications of astaxanthin. DAVID WATUMULL
Welcome to the first episode of our new War Stories series. This week, Dr. Lee Warren takes us back to 2004, sharing his experiences as a combat neurosurgeon deployed to the Iraq war. From personal challenges to professional fears, Dr. Warren explores the parallels between literal war and the battles we all face in life—whether they come as trauma, tragedy, or unexpected challenges. He shares lessons on preparation, resilience, and how the process of self-brain surgery can help us recover, rebuild, and thrive. If you're looking for tools to help you face life's challenges with hope and strength, this episode is for you. Click here for the transcript! What You'll Learn in This Episode: The parallels between war and personal challenges. Why preparation (“prehab”) is essential for resilience. Lessons from deployment that apply to life's battles. How to use gratitude and mindset shifts to reframe hardship. The importance of community, faith, and self-brain surgery in overcoming adversity. Resources Mentioned: Hope Is the First Dose by Dr. Lee Warren No Place to Hide by Dr. Lee Warren Dr. Lee Warren's Newsletter: drleewarren.substack.com Timeline's Mitopure: timeline.com – Use code drleewarren for 10% off. Connect with Dr. Lee Warren: Website: drleewarren.com Instagram: @drleewarren Podcast: Subscribe wherever you listen to podcasts! Chapters 00:00 Introduction and Podcast Overview 00:34 Reflecting on 20 Years Since Deployment 01:17 Lessons from the Iraq War 02:14 Applying Self Brain Surgery to Life's Battles 02:36 First War Story: Receiving Orders 03:50 Sponsor Message: Timeline 05:17 Preparing for Deployment 08:11 Facing the Unknown in Combat 11:32 Emotional and Personal Struggles 12:37 Types of Wars: Expected vs. Unexpected 13:27 Prehab: Preparing for Known Battles 16:46 Orders in Hand: Emotional Preparation 20:32 The Importance of Preparation 23:12 Biblical Perspective on Life's Struggles 24:09 Finding Faith in Hard Times 24:34 Preparing for Life's Challenges 24:59 Defining Your Belief System 26:04 Building Resilient Relationships 26:19 The Importance of Mental Preparation 26:47 Daily Gratitude Practice 28:32 Facing Life's Inevitable Wars 28:50 Planning for Potential Marital Issues 30:58 Financial Preparedness 32:32 Personal War Stories 35:46 The Impact of War on Personal Growth 38:14 The Power of Sharing War Stories 40:07 The Role of Faith and Community 43:53 Conclusion: Embracing Hope and Change This episode was sponsored by Timeline. Mitochondrial dysfunction as we age has been linked to muscle dysfunction, metabolism, overall energy levels, and resiliency. But what makes our mitochondria fail as we get older? It turns out to be related to a disruption in a process called mitophagy, the natural repair and recycling process that normally rebuilds and recreates healthy mitochondria to replace damaged ones. When mitophagy fails, mitochondria lose efficiency and cannot do their jobs, and we have a power failure. The compound that's key to keeping mitophagy happening normally is called Urolithin-A, and that compound is lacking in most of us because of a change over time in our gut microbiota. Timeline is renewing this process and making our mitochondria better with their product Mitopure. It will help you repair your cells, increase your strength, and become healthier. Check it out at timeline.com, and use the discount code leewarren for 10% off your first order. Resources and Links: I've created a free BRAIN Goals™ Guide for you! Click here to download the guide. It will help you align your mindset to your mission and set goals to make 2025 your best year yet! Be sure to check out my latest book, Hope Is the First Dose! Sign up for my weekly Self-Brain Surgery Newsletter here! Connect with me on Instagram @drleewarren Learn more about your ad choices. Visit megaphone.fm/adchoices