Podcasts about mitochondrial

Beyond Traditional Medicine: The Science of Regeneration & Cellular Health with CEO Mick Emandi and Dr. Greg Carder Is regenerative medicine the future of healthcare—or one of the most misunderstood fields in modern medicine? In this thought-provoking episode of The Hurricane H Show, Hurricane H is joined by Mick Emandi, CEO of Regen MDs, and Dr. Greg Carder for an in-depth conversation exploring the rapidly evolving world of regenerative medicine, stem cell therapies, molecular hydrogen, and cellular health. Drawing from decades of healthcare leadership and clinical experience, Mick shares why he shifted his focus toward regenerative therapies after seeing countless patients exhaust traditional treatment options. Together with Dr. Carder, we examine the science behind stem cell technology, hydrogen inhalation therapy, inflammation, recovery, mitochondrial function, and the body's remarkable ability to heal. This balanced discussion separates science from hype, addresses common misconceptions, and explores how emerging evidence-based therapies may reshape the future of personalized healthcare, longevity, and wellness. Ultra RSF1 - Beyond Stem Cells & Exosomes - Ultra RSF-1 Regen MDs Care - Regen MDs THE EMBC NETWORK - YouTube THEEMBCNETWORKOFFICIAL - YouTube Topics Covered ✔️ Regenerative medicine explained ✔️ Stem cell therapy: Facts vs. myths ✔️ Molecular hydrogen & hydrogen inhalation therapy ✔️ Mitochondrial and cellular health ✔️ Chronic pain, inflammation & recovery ✔️ Evidence-based healthcare innovation ✔️ Patient-centered regenerative medicine ✔️ Longevity and the future of wellness An insightful conversation for anyone interested in the future of healthcare, performance, and living healthier through science-driven innovation.

Beyond Traditional Medicine: The Science of Regeneration & Cellular Health with CEO Mick Emandi and Dr. Greg Carder Is regenerative medicine the future of healthcare—or one of the most misunderstood fields in modern medicine? In this thought-provoking episode of The Hurricane H Show, Hurricane H is joined by Mick Emandi, CEO of Regen MDs, and Dr. Greg Carder for an in-depth conversation exploring the rapidly evolving world of regenerative medicine, stem cell therapies, molecular hydrogen, and cellular health. Drawing from decades of healthcare leadership and clinical experience, Mick shares why he shifted his focus toward regenerative therapies after seeing countless patients exhaust traditional treatment options. Together with Dr. Carder, we examine the science behind stem cell technology, hydrogen inhalation therapy, inflammation, recovery, mitochondrial function, and the body's remarkable ability to heal. This balanced discussion separates science from hype, addresses common misconceptions, and explores how emerging evidence-based therapies may reshape the future of personalized healthcare, longevity, and wellness. Ultra RSF1 - Beyond Stem Cells & Exosomes - Ultra RSF-1 Regen MDs Care - Regen MDs THE EMBC NETWORK - YouTube THEEMBCNETWORKOFFICIAL - YouTube Topics Covered ✔️ Regenerative medicine explained ✔️ Stem cell therapy: Facts vs. myths ✔️ Molecular hydrogen & hydrogen inhalation therapy ✔️ Mitochondrial and cellular health ✔️ Chronic pain, inflammation & recovery ✔️ Evidence-based healthcare innovation ✔️ Patient-centered regenerative medicine ✔️ Longevity and the future of wellness An insightful conversation for anyone interested in the future of healthcare, performance, and living healthier through science-driven innovation.

Beyond Traditional Medicine: The Science of Regeneration & Cellular Health with CEO Mick Emandi and Dr. Greg Carder Is regenerative medicine the future of healthcare—or one of the most misunderstood fields in modern medicine? In this thought-provoking episode of The Hurricane H Show, Hurricane H is joined by Mick Emandi, CEO of Regen MDs, and Dr. Greg Carder for an in-depth conversation exploring the rapidly evolving world of regenerative medicine, stem cell therapies, molecular hydrogen, and cellular health. Drawing from decades of healthcare leadership and clinical experience, Mick shares why he shifted his focus toward regenerative therapies after seeing countless patients exhaust traditional treatment options. Together with Dr. Carder, we examine the science behind stem cell technology, hydrogen inhalation therapy, inflammation, recovery, mitochondrial function, and the body's remarkable ability to heal. This balanced discussion separates science from hype, addresses common misconceptions, and explores how emerging evidence-based therapies may reshape the future of personalized healthcare, longevity, and wellness. Ultra RSF1 - Beyond Stem Cells & Exosomes - Ultra RSF-1 Regen MDs Care - Regen MDs THE EMBC NETWORK - YouTube THEEMBCNETWORKOFFICIAL - YouTube Topics Covered ✔️ Regenerative medicine explained ✔️ Stem cell therapy: Facts vs. myths ✔️ Molecular hydrogen & hydrogen inhalation therapy ✔️ Mitochondrial and cellular health ✔️ Chronic pain, inflammation & recovery ✔️ Evidence-based healthcare innovation ✔️ Patient-centered regenerative medicine ✔️ Longevity and the future of wellness An insightful conversation for anyone interested in the future of healthcare, performance, and living healthier through science-driven innovation.

Beyond Traditional Medicine: The Science of Regeneration & Cellular Health with CEO Mick Emandi and Dr. Greg Carder Is regenerative medicine the future of healthcare—or one of the most misunderstood fields in modern medicine? In this thought-provoking episode of The Hurricane H Show, Hurricane H is joined by Mick Emandi, CEO of Regen MDs, and Dr. Greg Carder for an in-depth conversation exploring the rapidly evolving world of regenerative medicine, stem cell therapies, molecular hydrogen, and cellular health. Drawing from decades of healthcare leadership and clinical experience, Mick shares why he shifted his focus toward regenerative therapies after seeing countless patients exhaust traditional treatment options. Together with Dr. Carder, we examine the science behind stem cell technology, hydrogen inhalation therapy, inflammation, recovery, mitochondrial function, and the body's remarkable ability to heal. This balanced discussion separates science from hype, addresses common misconceptions, and explores how emerging evidence-based therapies may reshape the future of personalized healthcare, longevity, and wellness. Ultra RSF1 - Beyond Stem Cells & Exosomes - Ultra RSF-1 Regen MDs Care - Regen MDs THE EMBC NETWORK - YouTube THEEMBCNETWORKOFFICIAL - YouTube Topics Covered ✔️ Regenerative medicine explained ✔️ Stem cell therapy: Facts vs. myths ✔️ Molecular hydrogen & hydrogen inhalation therapy ✔️ Mitochondrial and cellular health ✔️ Chronic pain, inflammation & recovery ✔️ Evidence-based healthcare innovation ✔️ Patient-centered regenerative medicine ✔️ Longevity and the future of wellness An insightful conversation for anyone interested in the future of healthcare, performance, and living healthier through science-driven innovation.

All Yeptide Resources DianeKazer.com/YEPTIDES Join Our Elite VIP Tribe DianeKazer.com/VIP Apply to Become a 1-on-1 Patient DianeKazer.com/PATIENT TheWarriorCleanse.com We're comparing GLP-1s, Retatrutide, SLU-PP and the new oral GLP and revealing the root causes and lab markers that should be addressed before taking ANY of these. Most people are asking the wrong question. They're asking... "Which one helps me lose the most weight?" The better question is: "Why is my metabolism broken in the first place?" Because if you don't innerstand why you're gaining weight, exhausted, inflamed, insulin resistant, or unable to build muscle... you'll keep chasing the newest shiny object. 2026 has completely changed the metabolic medicine conversation. We're no longer talking about just appetite suppression. We're talking about restoring metabolism. And two names continue to dominate that conversation:

The Cobalamin is the gateway brain vitamin. Since B12 plays a role in so many foundational processes that power our minds and bodies, people should begin their Biohacking by ensuring they are getting enough of the B vitamins before diving into hardcore Nootropic or pharmaceutical solutions.Being the "King of B Vitamins," there's an abundance of research done on it; over 8000 articles of relevant research are published on PubMed, and over 700 human clinical trials in this century alone. Here we'll break down the recent performance enhancement studies...3:09 The Cobalamins4:44 Scientific research: Recent performance enhancement studies13:54 The Gateway Brain Vitamin 15:02 Energizing Nootropic19:40 Mitochondrial support21:02 Empowering neuroplasticity27:21 Vs Depression29:49 Deficiency32:22 Anti-Aging Vitamin34:19 Cognitive Enhancer35:56 Food Sources38:24 Cyanocobalamin vs Methylcobalamin vs Hydroxocobalamin41:00 Sources44:28 Getting B12 from a multivitamin?47:52 Recommended Daily50:19 Side Effects51:03 B12 misinformation01:00:49 ConclusionRead Meta-Analysis

A research roundup episode, where Dr. Gabriele Gallo (of KnowledgeIsWatt) and myself cover four recent research papers and how they might help us train better and improve our understanding of triathlon and endurance performance HIGHLIGHTS AND KEY TOPICS:  Do the same training program twice - get different results? (and how Gabriele and I disagree slightly on the conclusions to draw from this study) Strength training is beneficial for cycling performance, but how beneficial is it really? And is it beneficial for everybody? Finally, how should you structure your strength training program to make it so?  A massive review on the impact of different types of endurance training on mitochondrial and capillary growth, and VO2max improvements.  What separates athletes of different performance levels is not how high they can push their threshold as a percentage of VO2max, but how high the VO2max is in the first place.  SHOWNOTES, LINKS, RESOURCES AND RELATED EPISODES:  Follow Gabriele and KnowledgeIsWatt on his website, Substack and Instagram The shownotes for today's episode can be found here.  The full podcast episode archives (including category filters) can be found here.  Limited reproducibility of individual physiological adaptations to repeated endurance exercise training - Odden et al. 2026 Heavy strength training effects on physiological determinants of endurance cyclist performance: a systematic review with meta-analysis - Llanos-Lagos et al. 2025 Effects of Exercise Training on Mitochondrial and Capillary Growth in Human Skeletal Muscle: A Systematic Review and Meta-Regression - Mølmen et al. 2024 Elite Aerobic Endurance Performance: Is It Really Related to Lactate Threshold Expressed Relative to Peak Oxygen Uptake? - Johansen et al. 2025 Strength training improves performance and pedaling characteristics in elite cyclists - Rønnestad et al. 2014 Five-Minute Power-Based Test to Predict Maximal Oxygen Consumption in Road Cycling - Sitko et al. 2022 SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership. ZenAI is the next frontier of podcasting. It lets you turn your ideas into a podcast without any knowledge of audio editing, video, or production. You do the talking, and the AI handles the production, editing, clipping, and the rest, and you can direct your AI producer in plain English. You can even record from your phone, so no expensive studio gear is needed to sound great. ZenAI is a new product from Zencastr, a platform I've been a paying customer of for over nine years here at That Triathlon Show. ZenAI is currently in invite-only beta. Join the waitlist today here.LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we doContact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs)Subscribe to our NewsletterFollow us on InstagramLearn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals.HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released.Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far!Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones).Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What if one of the most powerful tools for improving health, recovery, longevity, and cellular performance isn't a supplement or medication—but heat?In this episode, we sit down with heat therapy and wellness expert Dr. Rachelle Reed to explore the science behind sauna therapy, red light therapy, photobiomodulation, heat exposure, recovery optimization, inflammation reduction, mitochondrial health, and healthy aging.Dr. Reed explains how strategic heat and light exposure can influence the body's natural healing mechanisms, support energy production, improve circulation, enhance recovery, and promote long-term vitality.We discuss the latest research on:• Sauna therapy and longevity• Red light therapy and photobiomodulation• Mitochondrial health and cellular energy production• Recovery optimization for athletes and high performers• Heat shock proteins and healthy aging• Reducing inflammation naturally• Improving circulation and cardiovascular health• Stress resilience and nervous system regulation• Biohacking tools for wellness and performance• Combining sauna, red light, nutrition, and lifestyle interventionsDr. Reed also shares practical recommendations for safely incorporating heat therapy and red light therapy into your daily routine, including protocols, common mistakes, and what the science says about achieving the best results.Whether you're interested in longevity, biohacking, wellness, athletic recovery, anti-aging strategies, cellular health, energy optimization, or improving overall quality of life, this conversation offers valuable insights into some of today's most exciting health technologies.About Dr. Rachelle ReedDr. Rachelle Reed is a researcher, educator, and expert in heat therapy, sauna protocols, red light therapy, photobiomodulation, recovery science, and integrative wellness. Her work focuses on helping individuals optimize health, performance, resilience, and longevity through evidence-based approaches that support the body's natural regenerative processes. Dr. Reed's experience spans Perspire Sauna Studios, Pure Barre, and Orange Theory.In This Episode You'll Learn:✔ How sauna therapy may support healthy aging and longevity✔ The science behind red light therapy and photobiomodulation✔ How heat affects mitochondria and cellular energy production✔ The connection between inflammation and chronic disease✔ Recovery strategies used by elite performers and athletes✔ How to create an effective sauna and red light routine✔ Emerging research on longevity and cellular resilienceSubscribe for more conversations on longevity, biohacking, human performance, cellular health, consciousness, wellness innovation, and the future of human potential.#RachelleReed #Sauna #RedLightTherapy #Longevity #Biohacking #Photobiomodulation #Mitochondria #CellularHealth #HealthyAging #Recovery #Wellness #HeatTherapy #HumanPerformance #Podcast

Send us Fan MailWhat if your body isn't working against you?What if it's making intelligent decisions based on the resources it has available?In this episode of It's Hertime, Cody sits down with biochemist and Functional Diagnostic Nutrition Practitioner Nick Dorsey for one of the most thought-provoking conversations we've had on the podcast.Together, they explore a powerful idea: the body is constantly evaluating its environment—assessing energy, nutrients, stress, inflammation, toxicity, and biological safety—to determine where its resources should go.When those resources are limited, the body may intentionally downregulate energy-intensive processes like fertility, hormone production, metabolism, immune regulation, and repair. Not because it's failing—but because it's adapting.Nick explains why symptoms such as fatigue, hormone imbalances, gut dysfunction, anxiety, weight loss resistance, and even unexplained infertility may be intelligent protective responses rather than isolated problems to “fix.”This conversation will challenge the way you think about health and introduce a systems-based framework that connects the microbiome, mitochondria, minerals, and nervous system into one beautifully integrated picture.If you've ever been told your labs are “normal” but you still don't feel like yourself, this episode offers a refreshing perspective on why that can happen—and what your body may actually be asking for.In this episode, we discuss:●Why the body is constantly making decisions behind the scenes●How the body decides where to spend its energy and resources●Why fertility is an energy and resource decision—not simply a hormone problem●Why “unexplained infertility” often isn't unexplained at all●Why normal lab work doesn't always mean the body has what it needs to heal or reproduce●The hidden resource economy behind hormone imbalance, chronic fatigue, thyroid dysfunction, gut issues, anxiety, and inflammation●The Four Pillars of Biological Readiness:●The microbiome●Mitochondrial health●Mineral balance●Nervous system regulation●What “biological safety” really means●How chronic stress, nutrient deficiencies, toxins, blood sugar instability, inflammation, and poor sleep influence every system in the body●Why symptom-chasing often keeps people stuck●What true resilience and healing actually look likeConnect with NickLearn more about Nick's work at Functional Chemistry.Follow Nick on Instagram: @nick.dorsey10You can also find him on YouTube: Functional Chemistry. Visit Nick's Website and QuizWant to Go Deeper?Connect with CodyOne of the themes that came up repeatedly in this conversation is the importance of mineral balance and understanding the body's unique patterns of adaptation.This is exactly why I use Hair Tissue Mineral Analysis (HTMA) in my practice.HTMA is a functional assessment that measures mineral patterns in the tissues—not just what's circulating in the blood—to help uncover stress patterns, metabolic tendencies, and mineral imbalances that may be influencing energy, hormones, thyroid function, nervous system regulation, and overall resilience.If you're tired of being told everything looks “normal” but you still don't feel like yourself, HTMA can provide a different lens for understanding what your body has been communicating all along.If you'd like to work with me or have an HTMA kit sent directly to your home, send me a DM on Instagram at @codyjeansanders with the word HTMA. I'd love to help you better understand your body's unique story.If you enjoyed this episode, please subscribe, leave a review, and share it with someone who needs to hear this conversation.Because sometimes the most important step toward healing isn't finding another protocol—it's understanding how brilliantly your body has been working to protect you all along.Did you learn something new today? Be sure to subscribe to this podcast and share this episode with all the girls you love. We would appreciate it if you'd also leave us a rating and review on iTunes.Want to join our Mixhers Girl community and keep this conversation going? We'd love to hear your thoughts, feelings and experiences! Join us HERE!Join Mixhers email list and be the first to have access to new products and be the girl in the know!Follow Cody Instagram:@codyjeansanders

Red grapes, beets, and leafy greens enhance nitric oxide and improve mitochondrial function, making them powerful tools for endurance and heart health. #Resveratrol #NitricOxide #BeetJuice #HealthTalks

Full show notes: https://bengreenfieldlife.com/mitrix In this episode with Tom Benson, founder and CEO of Mitrix, you'll hear why mitochondrial decline may be the actual root cause of aging rather than just a downstream symptom of it, and why most of the drugs developed so far to address it don't touch the real problem: damaged mitochondrial DNA. We discuss how Tom's company grows new, healthy mitochondria inside a bioreactor using banked stem cells, what mitochondrial transplantation actually looks like in real human cases already happening today, and the mouse study that gives this episode its name, in which severely aged mice receiving repeated mitochondrial injections were, according to the technicians running the experiment, climbing the walls of their cages by the very next day. Tom also touches on his original theory on the mitochondrial cycle of the body, how mitlets differ from naked mitochondria, and what his own MitoClock test reveals using nothing more than a urine sample. Tom Benson is the CEO and founder of Mitrix. He is a serial entrepreneur and scientist who has founded four successful software, hardware, and science startups. He has published dozens of articles and video lectures on mitochondrial science and cellular energetics, and developed original theories on the systemic transfer and distribution of mitochondria within higher organisms and how that affects health and lifespan. Episode Sponsors: Troov: An all-natural energy powder combining green tea caffeine, L-theanine, beetroot, amino acids, adaptogens, and electrolytes for steady energy and focus without the crash. Visit DrinkTroov.com/BEN and use code BEN for 30% off your first order, plus free shipping and a 30-day money-back guarantee. Our Place: Upgrade to a kitchen free of forever chemicals. Go to fromourplace.com/ben and use code BEN for 10% off sitewide. BON CHARGE: A holistic wellness brand with products that address sleep, performance, recovery, hormone balance, and inflammation. Go to boncharge.com/GREENFIELD and use code GREENFIELD to save 15%. Tecton Ketones: Bioidentical D-beta-hydroxybutyrate (BHB) for clean cognitive support, stable energy, and performance without the conversion step required by many ketone precursors. Visit tectonketones.com/ben and use code BEN for 16% off your first order. LYMA Laser: An advanced at-home skin technology backed by peer-reviewed research showing it influenced 45 genes in human skin compared to just one for an equivalent LED device. Visit lyma.life and use code BEN10 for 10% off for a limited time.See omnystudio.com/listener for privacy information.

PainExam Podcast Show Notes NAD+ Supplementation in Pain and Inflammation: Hype, Hope, or Emerging Science? Hosted by: PainExam Podcast Presented by: NRAP Academy (Neuromodulation, Regional Anesthesia & Pain) Host: David Rosenblum, MD Episode Overview In this episode of the PainExam Podcast, we explore the growing interest in NAD+ (Nicotinamide Adenine Dinucleotide) supplementation and its potential role in pain management, inflammation reduction, cellular recovery, and healthy aging. NAD+ is a naturally occurring coenzyme found in every living cell and is essential for energy production, mitochondrial function, DNA repair, and cellular resilience. As NAD+ levels decline with age, chronic stress, inflammation, and disease, researchers have begun investigating whether restoring NAD+ levels may improve outcomes in chronic pain conditions and inflammatory disorders. We review the current science, discuss potential mechanisms of action, and examine how NAD+ therapy is being integrated into regenerative medicine, wellness programs, and pain management practices. What is NAD+? NAD+ is a coenzyme involved in: ✅ Cellular energy production (ATP generation) ✅ Mitochondrial health ✅ DNA repair pathways ✅ Oxidative stress reduction ✅ Neuroprotection ✅ Cellular signaling ✅ Activation of longevity-associated proteins called sirtuins Without adequate NAD+, cells become less efficient at producing energy and managing inflammation. Why Might NAD+ Matter in Chronic Pain? Many chronic pain conditions involve: Mitochondrial dysfunction Oxidative stress Neuroinflammation Peripheral and central sensitization Impaired cellular recovery Researchers hypothesize that optimizing NAD+ levels may help address several of these pathways simultaneously. Potential areas of interest include: Neuropathic Pain NAD+ may support: Nerve repair Axonal recovery Mitochondrial function within neurons Reduction of oxidative injury Inflammatory Pain NAD+ influences inflammatory signaling pathways and may help modulate: Cytokine production Immune cell activity Cellular stress responses Fatigue and Recovery Patients with chronic pain frequently report: Fatigue Brain fog Reduced exercise tolerance Poor recovery Because NAD+ plays a critical role in energy metabolism, some clinicians report improvements in energy and recovery following supplementation. Potential Mechanisms of Action 1. Improved Mitochondrial Function Mitochondria generate ATP, the body's energy currency. Reduced NAD+ levels are associated with: Cellular aging Impaired energy production Increased inflammation Supplementation may help restore mitochondrial efficiency. 2. Activation of Sirtuins Sirtuins are proteins involved in: Cellular repair Longevity Metabolic regulation Inflammation control NAD+ serves as a critical substrate for sirtuin activity. 3. DNA Repair Support NAD+ is required for enzymes known as PARPs (Poly ADP Ribose Polymerases), which participate in DNA repair processes following cellular injury. 4. Reduction of Oxidative Stress Chronic inflammation often produces excessive reactive oxygen species (ROS). NAD+ may help maintain cellular antioxidant defenses and reduce oxidative injury. Routes of NAD+ Supplementation Intravenous (IV) NAD+ Most commonly marketed in wellness and recovery clinics. Potential advantages: Direct systemic delivery Avoids gastrointestinal absorption issues Allows higher dosing protocols Potential limitations: Cost Time commitment Variable evidence base Oral Precursors Rather than NAD+ itself, many supplements provide precursors such as: Nicotinamide Riboside (NR) Nicotinamide Mononucleotide (NMN) These compounds are converted into NAD+ within the body. What Does the Evidence Show? Current evidence remains preliminary. While preclinical and mechanistic studies are promising, large-scale randomized controlled trials evaluating NAD+ specifically for chronic pain are still limited. Areas under active investigation include: Neuropathic pain Neurodegenerative disorders Chronic fatigue syndromes Recovery optimization Healthy aging Patients should understand that NAD+ therapy remains an emerging treatment rather than a standard evidence-based pain intervention. Safety Considerations Reported side effects may include: Nausea Flushing Chest tightness during rapid infusions Headache Fatigue Lightheadedness Most adverse effects appear infusion-rate dependent and can often be minimized through slower administration protocols. Patients should discuss treatment with a qualified healthcare professional, especially if they have: Cardiovascular disease Active cancer Significant medical comorbidities Clinical Pearls for Pain Physicians ✔ Consider NAD+ as a potential adjunct—not a replacement—for evidence-based pain care. ✔ Continue emphasizing exercise, sleep optimization, nutrition, behavioral health, and appropriate interventional therapies. ✔ Discuss realistic expectations with patients. ✔ Recognize that evidence continues to evolve. ✔ Focus on patient-centered outcomes rather than laboratory markers alone. Key Takeaways NAD+ is essential for cellular energy production and repair. Declining NAD+ levels may contribute to aging, inflammation, and chronic disease. Early evidence suggests possible benefits in inflammation, recovery, fatigue, and nerve health. Robust pain-specific clinical trials remain limited. NAD+ therapy should currently be viewed as an adjunctive and investigational strategy in pain management. Resources for Physicians Pain Medicine Board Preparation Prepare for the ABA Pain Medicine Boards with:

    PainExam Podcast Show Notes NAD+ Supplementation in Pain and Inflammation: Hype, Hope, or Emerging Science? Hosted by: PainExam Podcast Presented by: NRAP Academy (Neuromodulation, Regional Anesthesia & Pain) Host: David Rosenblum, MD Episode Overview In this episode of the PainExam Podcast, we explore the growing interest in NAD+ (Nicotinamide Adenine Dinucleotide) supplementation and its potential role in pain management, inflammation reduction, cellular recovery, and healthy aging. NAD+ is a naturally occurring coenzyme found in every living cell and is essential for energy production, mitochondrial function, DNA repair, and cellular resilience. As NAD+ levels decline with age, chronic stress, inflammation, and disease, researchers have begun investigating whether restoring NAD+ levels may improve outcomes in chronic pain conditions and inflammatory disorders. We review the current science, discuss potential mechanisms of action, and examine how NAD+ therapy is being integrated into regenerative medicine, wellness programs, and pain management practices. What is NAD+? NAD+ is a coenzyme involved in: ✅ Cellular energy production (ATP generation) ✅ Mitochondrial health ✅ DNA repair pathways ✅ Oxidative stress reduction ✅ Neuroprotection ✅ Cellular signaling ✅ Activation of longevity-associated proteins called sirtuins Without adequate NAD+, cells become less efficient at producing energy and managing inflammation. Why Might NAD+ Matter in Chronic Pain? Many chronic pain conditions involve: Mitochondrial dysfunction Oxidative stress Neuroinflammation Peripheral and central sensitization Impaired cellular recovery Researchers hypothesize that optimizing NAD+ levels may help address several of these pathways simultaneously. Potential areas of interest include: Neuropathic Pain NAD+ may support: Nerve repair Axonal recovery Mitochondrial function within neurons Reduction of oxidative injury Inflammatory Pain NAD+ influences inflammatory signaling pathways and may help modulate: Cytokine production Immune cell activity Cellular stress responses Fatigue and Recovery Patients with chronic pain frequently report: Fatigue Brain fog Reduced exercise tolerance Poor recovery Because NAD+ plays a critical role in energy metabolism, some clinicians report improvements in energy and recovery following supplementation. Potential Mechanisms of Action 1. Improved Mitochondrial Function Mitochondria generate ATP, the body's energy currency. Reduced NAD+ levels are associated with: Cellular aging Impaired energy production Increased inflammation Supplementation may help restore mitochondrial efficiency. 2. Activation of Sirtuins Sirtuins are proteins involved in: Cellular repair Longevity Metabolic regulation Inflammation control NAD+ serves as a critical substrate for sirtuin activity. 3. DNA Repair Support NAD+ is required for enzymes known as PARPs (Poly ADP Ribose Polymerases), which participate in DNA repair processes following cellular injury. 4. Reduction of Oxidative Stress Chronic inflammation often produces excessive reactive oxygen species (ROS). NAD+ may help maintain cellular antioxidant defenses and reduce oxidative injury. Routes of NAD+ Supplementation Intravenous (IV) NAD+ Most commonly marketed in wellness and recovery clinics. Potential advantages: Direct systemic delivery Avoids gastrointestinal absorption issues Allows higher dosing protocols Potential limitations: Cost Time commitment Variable evidence base Oral Precursors Rather than NAD+ itself, many supplements provide precursors such as: Nicotinamide Riboside (NR) Nicotinamide Mononucleotide (NMN) These compounds are converted into NAD+ within the body. What Does the Evidence Show? Current evidence remains preliminary. While preclinical and mechanistic studies are promising, large-scale randomized controlled trials evaluating NAD+ specifically for chronic pain are still limited. Areas under active investigation include: Neuropathic pain Neurodegenerative disorders Chronic fatigue syndromes Recovery optimization Healthy aging Patients should understand that NAD+ therapy remains an emerging treatment rather than a standard evidence-based pain intervention. Safety Considerations Reported side effects may include: Nausea Flushing Chest tightness during rapid infusions Headache Fatigue Lightheadedness Most adverse effects appear infusion-rate dependent and can often be minimized through slower administration protocols. Patients should discuss treatment with a qualified healthcare professional, especially if they have: Cardiovascular disease Active cancer Significant medical comorbidities Clinical Pearls for Pain Physicians ✔ Consider NAD+ as a potential adjunct—not a replacement—for evidence-based pain care. ✔ Continue emphasizing exercise, sleep optimization, nutrition, behavioral health, and appropriate interventional therapies. ✔ Discuss realistic expectations with patients. ✔ Recognize that evidence continues to evolve. ✔ Focus on patient-centered outcomes rather than laboratory markers alone. Key Takeaways NAD+ is essential for cellular energy production and repair. Declining NAD+ levels may contribute to aging, inflammation, and chronic disease. Early evidence suggests possible benefits in inflammation, recovery, fatigue, and nerve health. Robust pain-specific clinical trials remain limited. NAD+ therapy should currently be viewed as an adjunctive and investigational strategy in pain management. Resources for Physicians Pain Medicine Board Preparation Prepare for the ABA Pain Medicine Boards with:

    PainExam Podcast Show Notes NAD+ Supplementation in Pain and Inflammation: Hype, Hope, or Emerging Science? Hosted by: PainExam Podcast Presented by: NRAP Academy (Neuromodulation, Regional Anesthesia & Pain) Host: David Rosenblum, MD Episode Overview In this episode of the PainExam Podcast, we explore the growing interest in NAD+ (Nicotinamide Adenine Dinucleotide) supplementation and its potential role in pain management, inflammation reduction, cellular recovery, and healthy aging. NAD+ is a naturally occurring coenzyme found in every living cell and is essential for energy production, mitochondrial function, DNA repair, and cellular resilience. As NAD+ levels decline with age, chronic stress, inflammation, and disease, researchers have begun investigating whether restoring NAD+ levels may improve outcomes in chronic pain conditions and inflammatory disorders. We review the current science, discuss potential mechanisms of action, and examine how NAD+ therapy is being integrated into regenerative medicine, wellness programs, and pain management practices. What is NAD+? NAD+ is a coenzyme involved in: ✅ Cellular energy production (ATP generation) ✅ Mitochondrial health ✅ DNA repair pathways ✅ Oxidative stress reduction ✅ Neuroprotection ✅ Cellular signaling ✅ Activation of longevity-associated proteins called sirtuins Without adequate NAD+, cells become less efficient at producing energy and managing inflammation. Why Might NAD+ Matter in Chronic Pain? Many chronic pain conditions involve: Mitochondrial dysfunction Oxidative stress Neuroinflammation Peripheral and central sensitization Impaired cellular recovery Researchers hypothesize that optimizing NAD+ levels may help address several of these pathways simultaneously. Potential areas of interest include: Neuropathic Pain NAD+ may support: Nerve repair Axonal recovery Mitochondrial function within neurons Reduction of oxidative injury Inflammatory Pain NAD+ influences inflammatory signaling pathways and may help modulate: Cytokine production Immune cell activity Cellular stress responses Fatigue and Recovery Patients with chronic pain frequently report: Fatigue Brain fog Reduced exercise tolerance Poor recovery Because NAD+ plays a critical role in energy metabolism, some clinicians report improvements in energy and recovery following supplementation. Potential Mechanisms of Action 1. Improved Mitochondrial Function Mitochondria generate ATP, the body's energy currency. Reduced NAD+ levels are associated with: Cellular aging Impaired energy production Increased inflammation Supplementation may help restore mitochondrial efficiency. 2. Activation of Sirtuins Sirtuins are proteins involved in: Cellular repair Longevity Metabolic regulation Inflammation control NAD+ serves as a critical substrate for sirtuin activity. 3. DNA Repair Support NAD+ is required for enzymes known as PARPs (Poly ADP Ribose Polymerases), which participate in DNA repair processes following cellular injury. 4. Reduction of Oxidative Stress Chronic inflammation often produces excessive reactive oxygen species (ROS). NAD+ may help maintain cellular antioxidant defenses and reduce oxidative injury. Routes of NAD+ Supplementation Intravenous (IV) NAD+ Most commonly marketed in wellness and recovery clinics. Potential advantages: Direct systemic delivery Avoids gastrointestinal absorption issues Allows higher dosing protocols Potential limitations: Cost Time commitment Variable evidence base Oral Precursors Rather than NAD+ itself, many supplements provide precursors such as: Nicotinamide Riboside (NR) Nicotinamide Mononucleotide (NMN) These compounds are converted into NAD+ within the body. What Does the Evidence Show? Current evidence remains preliminary. While preclinical and mechanistic studies are promising, large-scale randomized controlled trials evaluating NAD+ specifically for chronic pain are still limited. Areas under active investigation include: Neuropathic pain Neurodegenerative disorders Chronic fatigue syndromes Recovery optimization Healthy aging Patients should understand that NAD+ therapy remains an emerging treatment rather than a standard evidence-based pain intervention. Safety Considerations Reported side effects may include: Nausea Flushing Chest tightness during rapid infusions Headache Fatigue Lightheadedness Most adverse effects appear infusion-rate dependent and can often be minimized through slower administration protocols. Patients should discuss treatment with a qualified healthcare professional, especially if they have: Cardiovascular disease Active cancer Significant medical comorbidities Clinical Pearls for Pain Physicians ✔ Consider NAD+ as a potential adjunct—not a replacement—for evidence-based pain care. ✔ Continue emphasizing exercise, sleep optimization, nutrition, behavioral health, and appropriate interventional therapies. ✔ Discuss realistic expectations with patients. ✔ Recognize that evidence continues to evolve. ✔ Focus on patient-centered outcomes rather than laboratory markers alone. Key Takeaways NAD+ is essential for cellular energy production and repair. Declining NAD+ levels may contribute to aging, inflammation, and chronic disease. Early evidence suggests possible benefits in inflammation, recovery, fatigue, and nerve health. Robust pain-specific clinical trials remain limited. NAD+ therapy should currently be viewed as an adjunctive and investigational strategy in pain management. Resources for Physicians Pain Medicine Board Preparation Prepare for the ABA Pain Medicine Boards with:

Red and near-infrared light may be the most underestimated recovery tool in your environment, and the science behind what it actually does inside your cells is far more compelling than the wellness industry gives it credit for.   Scott Chaverri didn't set out to build one of the leading red light therapy companies in the country. He was a burnt-out caregiver looking for anything that would help him sleep and function after two years of watching his son fight cancer. He found red light therapy in 2017 and noticed real changes. When the price of adding more panels shocked him, he decided to build his own. Mito Red Light did a million dollars in sales its first year.   The science behind photobiomodulation is worth understanding. Red and near-infrared wavelengths penetrate several centimeters into the body and act directly on the mitochondria, accelerating ATP production and triggering downstream effects that include better circulation, reduced inflammation, and a meaningful boost in cellular melatonin. A study on elite female basketball players found serum melatonin levels rose 67% after a single 30-minute session, which lines up with the number one piece of feedback Mito receives from customers: better sleep. Scott's broader argument reframes the whole conversation too. Modern humans spend roughly 93% of their time indoors, and much of what red light therapy accomplishes is correcting a light deficiency most people don't know they have. For the biohacking crowd chasing marginal gains, that reframe matters.   Dr. Fix brings a clinician's perspective throughout, connecting photobiomodulation to the laser and dry needling work at PhysioRoom and asking the questions practitioners actually want answered: dosing, distance, timing, device selection, and when a panel outperforms a mask. The episode also gets into the single biggest reason people return their devices without ever giving them a real shot, and it has nothing to do with the technology.   Quotes “Modern humans have very indoor lifestyles and they're sunlight deficient." (08:44 | Scott Chaverri) "If the cells have more energy at their disposal, they can do their jobs better. And so theoretically, any cell that has mitochondria, which is every cell in the human body except red blood cells, has the potential to benefit from exposure to these wavelengths of light due to that increased ATP production." (11:36 | Scott Chaverri) "We're spending 93% of our time indoors. And so when they correct the deficiency, they notice that they're feeling better, they sleep better, whatever the case is." (09:01 | Scott Chaverri) "We just giving it a little bit more energy so it can do its job. It knows what to do. Just have to give it what it needs." (21:50 | Scott Chaverri) "The sun rises. We're meant to get copious amounts of red and infrared light at dawn. It's the reason why the sky is red at sunrise and sunset, because that's the only wavelengths that are reaching us. And so that is like the signal to wake up." (1:01:40 | Scott Chaverri) Connect with Scott Chaverri: Visit The Mito Red Light Website  Red Light Therapy (@mitoredlightofficial)   Scott worked for several Fortune 500 companies, in the business services, medical device, financial services and ecommerce industries. Having dealt with health challenges in childhood and early adulthood, Scott has always been passionate about all things health and wellness. Constantly learning, tinkering and evolving, his goal is to build Mito Red Light Inc into a preeminent health and wellness company empowering people with tools and information to optimize their performance and maximize their health spans.     SideKick Tool   Movemate: Award-Winning Active Standing Board 15% off Promo Code: DRA15   RAD Roller   Revogreen   HYDRAGUN    Athletic Brewing 20% off: ANDREWF20     Connect with Physio Room: Visit the Physio Room Website Follow Physio Room on Instagram Follow Physio Room on Facebook Andrew's Personal Instagram Andrew's Personal Facebook     Podcast production and show notes provided by HiveCast.fm

MOTS-c is encoded by mitochondrial DNA, which makes it quite unique compared to most peptides, which are usually encoded by nuclear DNA. This peptide helps our bodies adapt to stress, regulate energy production, and maintain metabolic balance—especially when it comes to burning fat and improving overall endurance. Read the Full Episode Transcript: https://pepties.com/mitochondrial-support-from-mots-c/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ Buy Peptides online at BioLongevity Labs: Use our link and enter COUPON CODE: PEPTIDEPODCAST  at checkout to receive 15% off your total order:  https://go.biolongevitylabs.com/SH5C Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less.  https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1)  Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners!  ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/

What if your child's ADHD symptoms were not just a behavior problem, but a metabolic issue happening underneath the surface? In this episode, Dana Kay explains how the Organic Acid Test, often called the OAT test, can offer a deeper look at how a child's body is functioning, from nutrient processing and neurotransmitter pathways to gut overgrowth, detox stress, mitochondrial function, and more. This episode is part of Dana's functional lab testing series, and it goes one layer deeper than food sensitivities, gut issues, or nutrient loss. Dana explains why some families can be doing "all the right things," like cleaning up the diet, removing triggers, and adding supplements, yet still feel stuck. The missing piece may not be what to add or remove. It may be whether the body is actually processing things the way it should. Dana walks parents through the six key areas the Organic Acid Test can help illuminate, including microbial overgrowth, mitochondrial function, neurotransmitter pathways, toxic exposure, methylation and detoxification, and functional nutrient needs. Most importantly, she explains why this test can help bridge the gap between symptoms and function, giving families a clearer, more targeted path forward. LINKS MENTIONED IN THE SHOW Order Lab Tests Here - https://adhdthriveinstitute.wellproz.com/patient/home ADHD Thrive Institute Website: https://adhdthriveinstitute.com/ Dana Kay Website: https://dana-kay.com/ Free Reduce ADHD Symptoms Naturally Masterclass: https://bit.ly/3GAbFQl Thriving with ADHD Book: https://adhdthriveinstitute.com/book/ KEY TAKEAWAYS [00:00] ADHD symptoms may not only be behavioral. They may be connected to deeper metabolic issues happening underneath the surface. [01:29] Some families still feel stuck even after improving diet, removing triggers, and adding supplements because the body may not be processing things properly. [01:59] The Organic Acid Test, or OAT test, is a urine test that looks at organic acids, which are byproducts of metabolism. [02:27] Organic acids act like "metabolic breadcrumbs," offering clues about energy production, detoxification, neurotransmitters, and gut microbes. [03:18] The OAT test can help show where systems are struggling and where things are breaking down in the body. [03:43] Dana emphasizes that patterns matter more than one isolated out-of-range marker. [04:37] Gut and microbial overgrowth can produce toxins that may affect the brain and contribute to mood swings, hyperactivity, sensory issues, aggression, and poor focus. [05:03] Mitochondrial function matters because low cellular energy can show up as brain fog, low motivation, poor resilience, and overwhelm. [05:33] The test can give insight into neurotransmitter pathways like dopamine and serotonin, which are connected to focus, motivation, mood, and calm. [08:00] The biggest takeaway: traditional labs often look for disease, while the OAT test looks at dysfunction, helping parents better understand the whole-body picture. MEMORABLE MOMENTS "What if your child's ADHD symptoms were not just a behavior problem, but a metabolic issue happening underneath the surface?" "There is a test that can show you all of that from one simple urine sample." "Parents are doing everything right, they're cleaning up the diet, they're removing triggers, they're adding some supplements, and yet their child is still struggling." "The missing question is not always what should we add or remove. It is, is the body actually processing things?" "It's leaving behind these little sort of metabolic breadcrumbs." "It's not just telling us what is happening, it's telling us where things are breaking down in the body." "But the patterns are the more important thing." "You cannot fix neurotransmitters if the body does not have the nutrients or the pathways to make them properly." "This test looks at dysfunction." "You can stop guessing, you can stop jumping from one thing to the next, and you can start making sort of these really targeted decisions." DANA KAY RESOURCES

Vertical jump improved by over three centimetres in elite soccer players after just six weeks, simply by targeting one overlooked part of cellular biology: the mitochondria. Angela Foster talks with Dr Anurag Singh, Chief Medical Officer at Timeline, about the science of mitophagy, the process that clears out dysfunctional mitochondria, and how the clinically studied compound urolithin A supports it. They walk through real clinical trial data spanning soccer players, elite weightlifters and Olympic-level runners, with a particular focus on findings in women, exploring measurable gains in strength, power and recovery markers like reduced muscle damage and perceived effort. Listeners will learn why mitochondrial renewal takes weeks rather than days to show up, what it actually means when energy dips after stopping supplementation and rebounds on restarting, and why this matters especially for women navigating perimenopause, when recovery and inflammation can shift noticeably. Tune in to understand what's really happening at the cellular level behind your energy and recovery. KEY TAKEAWAYS Understand mitochondrial health as a three-stage cycle: biogenesis (creating new mitochondria), fission and fusion (making existing ones more efficient), and mitophagy (clearing out dysfunctional ones). Neglecting that final clearance step is, as Dr Singh puts it, like never taking the garbage out of a cluttered house. Expect mitochondrial and performance benefits to build gradually rather than instantly. Clinical studies show improved mitochondrial health in muscle tissue after one month, with measurable strength and power gains showing up after two to four months, so don't judge a mitochondria-targeted intervention by how you feel after a week. Pay attention to recovery markers, not just strength numbers, when evaluating training interventions. In a four-week study with elite runners, those taking mitopure showed lower rate of perceived exertion and lower creatine kinase, a muscle damage marker, suggesting easier recovery rather than just raw performance gains. Try a deliberate break from a supplement or intervention to gauge whether it's actually working for you. Both Angela and Dr Singh independently noticed an energy dip after stopping urolithin A supplementation, which is a practical way to separate real effect from placebo. Look for research that specifically includes women, since women are historically underrepresented in supplement and performance studies. Timeline's trials run roughly two-thirds female participants, which matters for understanding how recovery and inflammation patterns shift during phases like perimenopause. STANDOUT QUOTES "If we have a super cluttered house, there's only so much we can do to improve it. At one point, we've got to take out the garbage." — Dr Anurag Singh "Rome wasn't built in a day." — Dr Anurag Singh "It's the only thing we know outside of exercise and fasting that hits that mitochondria specific autophagy." — Dr Anurag Singh "I feel like I can do everything and have fun with my kids." — Angela Foster "That's the reason we're doing all this, right? It's our life. We want to live it healthily, fully." — Dr Anurag Singh VALUABLE RESOURCES •  Take the BioSyncing Quiz to help you understand what's actually happening in your body and how to fix it.

We've been taught to treat chronic diseases as isolated problems to be diagnosed and managed. But these conditions may have more in common than conventional medicine has traditionally recognized. On this episode of The Dr. Hyman Show, I'm joined by physician and researcher Dr. Terry Wahls, who transformed her understanding of disease after developing progressive multiple sclerosis. We discuss the emerging science behind mitochondria, inflammation, nutrition, the microbiome, and why creating health may be just as important as treating disease itself. We explore: What Dr. Wahls discovered about cellular health while searching for answers beyond conventional treatment Why mitochondria may play a central role in conditions like MS, Alzheimer's, Parkinson's, depression, and chronic fatigue How food, sleep, movement, and stress directly influence inflammation, energy production, and brain health Why focusing only on symptom suppression may overlook the deeper biological dysfunction driving chronic disease What “creating health” actually looks like in practice—and how small daily habits can influence how you feel and function over time What makes this conversation so compelling is that Dr. Wahls' story challenges many of the assumptions we have about chronic disease and recovery. For me, it really highlights how profoundly nutrition, sleep, movement, and stress can shape the body's ability to adapt and recover over time. View Show Notes From This Episode Sign up for Dr. Hyman's Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by fatty15, Big Bold Health, Timeline, BON CHARGE, BIOptimizers, and Made In. Head to fatty15.com/HYMAN today and use code HYMAN for 15% off your 90-day subscription Starter Kit. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Visit madeincookware.com and use code HYMAN10 for 10% off your order. (0:00) Dr. Terry Wahls' illness journey, Dr. Mark Hyman's intro, and sponsor mentions (2:54) Dr. Wahls and Dr. Hyman discuss their medical histories (4:00) Dr. Wahls' experience with multiple sclerosis (7:08) Dietary changes and physical improvements (9:09) Environmental factors in autoimmune diseases (11:17) Resistance in the medical system to new approaches (12:26) Integrating basic science into clinical practice (15:32) Mitochondrial support supplements (20:24) Mitochondria's role in energy-intensive tissues (22:11) Functional medicine and Dr. Wahls' continued health journey (23:49) Nutrient-focused dietary approach and recovery (26:13) Development and application of the Wahls diet (27:35) Nutrient-rich food categories and health benefits (30:11) NIH funding and functional medicine research potential (34:00) Success stories from the therapeutic lifestyle clinic (39:28) Creating health versus treating disease (44:10) Expanding research to other chronic illnesses (45:40) Latest clinical trials and future research directions (47:49) Advances in chronic disease treatment science (49:05) Predicting diet effectiveness: microbiome and genetics (50:00) Microbiome research and multiple sclerosis (51:18) A new theory of human biology in medicine (53:01) Creating health through lifestyle changes (55:13) Need for multimodal interventions in research (58:20) Funding challenges and philanthropy's role (59:08) Comprehensive approaches to complex diseases (1:01:05) Potential to reverse genetic diseases with lifestyle changes (1:07:24) Strategies for creating a healthy human (1:08:01) Upcoming research and initiatives by Dr. Wahls

Last Call for Root Cause Reset! Starts June 18 --> DianeKazer.com/RCR  Join Our Elite VIP Tribe --> DianeKazer.com/VIP All Yeptide Resources ->DianeKazer.com/YEPTIDES Apply to Become a 1-on-1 Patient --> DianeKazer.com/PATIENT Can we all agree that life feels a little... extra right now? The pace of life keeps speeding up. The cost of everything seems to be going up. The news gives us 47 new reasons to feel stressed before we've even finished our morning coffee. We're literally eating and drinking 'food' with 'frenzy' energy! I'm right there with you! People are worried about their finances, their families, their future, their health and honestly... sometimes just remembering where they put their phone. (Only to realize it's in their hand.

Sandy spent years misdiagnosed with Type 2 diabetes and battling medical gaslighting. Discover how the RADIANT study and AI uncovered her true diagnosis: Maternally Inherited Diabetes and Deafness. ABLEnow save for today's needs or invest for tomorrow Eversense CGM Medtronic Diabetes Tandem Mobi ** Use code JUICEBOX to save 20% at Cozy Earth  CONTOUR NextGen smart meter and CONTOUR DIABETES app Dexcom G7 Go tubeless with Omnipod 5 or Omnipod DASH * Get your supplies from US MED  or call 888-721-1514 Touched By Type 1 Take the T1DExchange survey Apple Podcasts> Subscribe to the podcast today! The podcast is available on Spotify, Google Play, iHeartRadio, Radio Public, Amazon Music and all Android devices The Juicebox Podcast is a free show, but if you'd like to support the podcast directly, you can make a gift here or buy me a coffee. Thank you! *The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.  ** t:slim X2 or Tandem Mobi w/ Control-IQ+ technology (7.9 or newer). RX ONLY. Indicated for patients with type 1 diabetes, 2 years and older. BOXED WARNING:Control-IQ+ technology should not be used by people under age 2, or who use less than 5 units of insulin/day, or who weigh less than 20 lbs. Safety info: tandemdiabetes.com/safetyinfo Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan.  If the podcast has helped you to live better with type 1 please tell someone else how to find it!  

Send Vanessa a Text MessageA special listener discount is available for Mara Labs products featured in this episode: Explore Mara Labs (Code is VANESSA)If you enjoy the podcast and want to support Vanessa's work, you can do so here: Buy Me a Coffee – Intentionally WellIn this episode, I'm joined by David Roberts, founder of Mara Labs, for a conversation exploring cellular health, modern environmental stressors, and the body's natural resilience systems.David's journey into this space began after his late wife Mara's cancer diagnosis, which led him to deeply explore plant-based compounds and how they interact with cellular protection and repair mechanisms. That path eventually led to the development of BrocElite, a stabilized sulforaphane supplement designed to support detoxification pathways, mitochondrial function, and overall cellular resilience.We discuss topics including sulforaphane, oxidative stress, detoxification and autophagy pathways, metabolic health and GLP-1 signaling, genetic variability such as MTHFR and COMT, and how modern environmental exposures like microplastics may be impacting overall health.This is a wide-ranging conversation aimed at helping make complex biology more understandable and grounded in real-life application.Key Topics Covered: Sulforaphane and cellular defense systems  Detoxification pathways and autophagy  Mitochondrial health and oxidative stress  Modern environmental exposures (including microplastics)  Metabolic health and GLP-1 signaling  Genetic variability (MTHFR / COMT) and sensitivity  Why some people feel more reactive in today's environment Sulforaphane and pet health BrocElite and Mara Labs story Connect with David:Mara Labs on InstagramExplore Mara LabsConnect with Vanessa and the podcast: IWP Website: Intentionally Well PodcastIWP Recommended ProductsPodcast on InstagramVanessa on InstagramPodcast on YouTubeVanessa on TikTokVanessa on XEmail: intentionallywellpodcast@gmail.comSupport the showThis episode is for informational purposes only. Please consult a trusted health practitioner for individual concerns.

What if fatigue, inflammation, poor recovery, hormone issues, bloating, brain fog, and "feeling stuck" are not simply about doing more… …but about impaired FLOW inside the body? In Part Three of The Terrain First Series: Flow, Signals & the Future You, Debbie Potts dives deep into the physiology behind her F.L.O.W. Foundation™ and explains why healing depends on movement, communication, oxygen delivery, drainage, and nervous system safety. In this episode, you'll learn: What F.L.O.W. stands for: Neural FLOW Lymphatic FLOW Oxygen FLOW Waste & Bile FLOW Why the nervous system controls digestion, recovery, and repair How chronic stress physiology may impair stomach acid, bile flow, motility, and mitochondrial function Why the lymphatic system is one of the most overlooked systems in modern health The connection between oxygen delivery, nitric oxide, mitochondria, and metabolic resilience Why "Drainage Before Detox" matters How sluggish bile flow may contribute to hormone recirculation, inflammation, and digestive dysfunction Why high performers often stay stuck in survival physiology despite "doing everything right" How the body constantly asks: Am I safe? Can I recover? Should I build or defend? Debbie also connects the dots between: The Cell Danger Response Vagal tone Mitochondrial communication Inflammation signaling Metabolic flexibility PNOĒ metabolic testing Terrain First physiology The FutureYou Blueprint™ This episode is a deep dive into why the body cannot heal efficiently when information, oxygen, nutrients, hormones, immune signals, and waste cannot move through the system properly. Because healing is not about forcing the body. It's about creating the conditions where the body finally feels safe enough to repair. Learn more about coaching, PNOĒ metabolic testing, and The FutureYou Blueprint™ at: https://debbiepotts.net Subscribe to Coach Debbie Potts on YouTube: https://www.youtube.com/@coachdebbiepotts #TerrainFirst #FutureYouBlueprint #FlowFoundation #VagusNerve #Mitochondria #MetabolicHealth #FunctionalMedicine #GutHealth #HormoneHealth #PNOE #Longevity #CoachDebbiePotts #CellDangerResponse #MetabolicFlexibility #HealthyAging

Why does exercise feel harder now—even though you're still training? Why does recovery take longer? Why are you doing "all the right things" but still struggling with fatigue, muscle loss, slower metabolism, or reduced performance? In Part 4 of my Terrain First Series, we dive into the O in the FLOW Method: O = Oxygen Flow Because Oxygen Flow is about much more than breathing. It influences: ✓ Energy production (ATP) ✓ Recovery capacity ✓ Muscle building and repair ✓ Mitochondrial health ✓ Nervous system regulation ✓ Nitric oxide production ✓ Metabolic flexibility ✓ Healthy aging and resilience In this episode, we explore: • What Oxygen Flow actually means • Why exercise feels harder after 40 • The connection between oxygen, mitochondria, and energy production • How nitric oxide affects circulation and performance • Why the vagus nerve influences breathing and recovery • Signs your Oxygen Flow may be impaired • Practical strategies to improve oxygen delivery, utilization, recovery, and resilience If you're an active adult, endurance athlete, high performer, or someone trying to improve metabolism and age stronger—not slower—this episode is for you. Because sometimes the problem isn't motivation. Sometimes the problem is physiology. Learn more about PNOĒ metabolic testing, coaching, and The FutureYou Blueprint: www.debbiepotts.net COMMENT BELOW: Have you noticed recovery getting harder as you age? #Metabolism #Recovery #HealthyAging #MidlifeFitness #VO2Max #Mitochondria #Hormones #Perimenopause #MenopauseFitness #PNOE #Fatigue #EnduranceAthlete #MuscleHealth #Biohacking #FutureYou

You're not imagining your fibromyalgia pain or symptoms. Discover common fibromyalgia causes and triggers, and learn how to find fibromyalgia relief by addressing the underlying issue.0:00 Introduction: Fibromyalgia explained 0:42 Fibromyalgia causes and triggers 1:45 Low vitamin D and fibromyalgia3:19 Mitochondrial damage and fibromyalgia symptoms5:00 What to do for fibromyalgia relief5:31 Fibromyalgia research and recovery7:58 Fixing low vitamin D 8:39 Magnesium deficiency and fibromyalgia symptoms 10:34 More fibromyalgia relief tips

Long COVID and sports injuries are becoming impossible to ignore—and this episode explores why more athletes may be dealing with fatigue, soft tissue breakdown, and prolonged recovery after viral illness. In this powerful conversation, Dr. Greg Jones sits down with Dr. Muhammad Mansour, a naturopathic doctor and regenerative medicine specialist who treats elite athletes at the highest levels.In this episode, you'll learn how long COVID may affect skeletal muscle, mitochondrial function, exercise tolerance, and systemic inflammation—and why these issues can persist even after the initial infection appears to resolve. Dr. Mansour explains how athletes can miss early warning signs, why “pushing through” fatigue may backfire, and how a more individualized recovery strategy may be critical in the post-pandemic era.If you're an athlete, coach, practitioner, or health-conscious listener trying to understand the intersection of long COVID, inflammation, and injury risk, this episode offers a science-informed perspective on what recovery may require now.

What if your fatigue, brain fog, stubborn weight gain, slow recovery, and lack of motivation all traced back to one hidden problem inside your cells?Your mitochondria are the tiny energy factories that power every organ, every thought, every heartbeat, and every movement you make. But modern stress, toxins, poor nutrition, aging, and environmental overload are silently damaging them—leaving millions running on empty.In this eye-opening episode, I reveal the ultimate biohacker's guide to mitochondrial support supplements and how optimizing your cellular energy can completely transform your health, metabolism, performance, and longevity.If you're constantly tired, battling brain fog, struggling to lose weight, or looking for the next level of health optimization, this episode could change how you think about energy forever. Supplements Featured In This Episode:• Acceleradine® Iodine https://www.acceleratedhealthproducts.com/products/acceleradine-iodine-supplement  • Accelerated Liver Care® https://www.acceleratedhealthproducts.com/products/accelerated-liver-care• Accelerated AMINOS® https://www.acceleratedhealthproducts.com/products/accelerated-aminos • Accelerated BIO PEPTIDES™ https://www.acceleratedhealthproducts.com/products/accelerated-collagen-peptides• Accelerated Scalar Copper® https://www.acceleratedhealthproducts.com/products/accelerated-scalar-copper • Accelerated Methylene Blue® https://www.acceleratedhealthproducts.com/products/accelerated-methylene-blue-supplement Not sure what food to eat and avoid? This guide is for you.⬇️

When my daughter was six months old, her platelet count dropped to 2,000. Over the next two years she was diagnosed with a mitochondrial disease (MELAS), lupus, and immune thrombocytopenia (ITP), and was seen by nine different specialists. Not one of them connected those findings to each other. This is the story of what almost losing her taught me about chronic disease, why our current model of medicine keeps failing complex and chronically ill clients, and why I am back on the podcast after almost a decade away. I am Andrew Reid, founder of Medgeeks. I trained as a Physician Assistant, spent five years in primary care, and have spent over a decade since educating clinicians. None of it prepared me for my own daughter. To help her, I had to go back and learn the biology underneath chronic disease: mitochondrial medicine, biochemistry, molecular biology, genetics, metabolomics, and clinical nutrition. What I found changed how I think about every client I see. Going forward, this show is about that biology and the clinical reasoning that follows from it. Mitochondrial function, the cell danger response, metabolic health, autoimmune disease, insulin resistance, and the systems-based, root-cause approach to chronic disease that conventional training leaves out. We also get into the other side of that same continuum: building muscle, exercise as medicine, sleep, nutrition, and the levers that move someone toward genuinely optimal health. The goal is simple: better health, with better science. Whether you are a clinician reasoning through complex clients, someone facing chronic illness in your own life or your family's, or you are already healthy and want to understand how to optimize and protect that health for the long run, this is the work I want to do in front of you. Learn more here: medgeeks.co If this resonated, the best thing you can do is follow the show wherever you listen and leave a review. It genuinely helps more clinicians and more families find this work. Thank you for being here.

In this episode of the Neuroveda Podcast for Complex Health, Gillian Ehrlich sits down with returning guest Dr. Dawn Ibsen, compounding pharmacist and passionate advocate for personalized medicine. Together they unpack the science, history, and growing interest around methylene blue — from its origins as a treatment for malaria to its modern use in brain health, mitochondrial support, longevity, and biohacking.They also dive into the rapidly changing world of compounding pharmacies, including concerns surrounding compounded thyroid medications, the evolving landscape of peptide access, and the balance between innovation, safety, and patient care. This conversation explores what happens when cutting-edge medicine meets regulation and why personalized treatment still matters.Topics include:• Methylene blue safety, dosing, and mechanisms• Mitochondrial health and energy production• Compounding pharmacy quality and patient advocacy• Thyroid medication changes• Peptide regulation and current challenges• The future of personalized medicineBio: Dr. Dawn Ipsen, PharmD, FAPC, FACVP, FACA is a compounding pharmacist with more than 25-years of experience serving human and veterinary patients. She is the owner of two community-based compounding pharmacies in Washington state and is recognized for her expertise in personalized medication therapy, quality compounding practices, and patient-centered care.Dr. Ipsen holds an APC Fellowship and is also a Fellow of the American College of Veterinary Pharmacists and American College of Apothecaries, reflecting her advanced training and leadership in both human and veterinary compounding. In addition, she is a clinical instructor for the University of Washington School of Pharmacy and an affiliate faculty member for Bastyr University. Her professional focus includes women's health, hormone therapy, low-dose naltrexone, dermatology compounding, and complex veterinary medication solutions for small animals, exotic pets, and large animal patients.Dr. Ipsen is deeply engaged in pharmacy advocacy, education, and legislative efforts to protect patient access to compounded medications. She currently holds an APC Board of Directors position and is the founding chair for the WA State Pharmacy Association (WSPA) - Compounding Special Interest Group. The WSPA awarded her with the Distinguished Leadership Award in 2023 and the UW School of Pharmacy Distinguished Alumni Award in 2021. Dr. Ipsen regularly collaborates with prescribers, healthcare professionals, and educators to improve the therapeutic outcomes, health, education and vitality of the communities we serve.

All links here: ⁠https://hunterwilliamshealth.com/linksSS-31 continues to be one of my favorite peptides of all time, and the more data that comes out on it, the more I think every person over 25 has a use case for it.In this masterclass, I'm breaking down everything I know about SS-31. We cover what it actually does at the cellular level, why it's the first FDA-approved mitochondrial peptide, and why it works differently than almost every other peptide out there. No receptor binding. It goes inside your cells, binds to cardiolipin, and stabilizes the structure of your mitochondria.I walk through the three dosing tiers I use with people, my take on cycling, why I run SS-31 before MOTS-c, how to stack it with GLPs, GH peptides, and the healing peptides, and what to actually track when you're on it. I also cover the troubleshooting stuff people ask me about constantly. Why don't I feel anything? Should I cycle? What about the headaches in the first two weeks?If you're a clinician or just researching for yourself, this is the complete user's guide.For entertainment purposes only.Timestamps00:00 Intro01:00 What this masterclass covers03:18 Why SS-31 matters and what makes it different03:46 FDA approval and the Forzenity brand name04:50 Peptide foundations and how SS-31 is made05:52 The SS-31 sequence and the Seto-Schiller naming origin06:40 Mitochondria 101 and why ATP matters07:28 Mitochondrial dysfunction across chronic disease08:34 Cardiolipin, cristae, and Barth syndrome09:34 Why SS-31 is not a direct antioxidant10:46 How SS-31 actually works (the upstream Godfather effect)11:12 Why no receptor means no desensitization13:36 Who SS-31 is for (mid-30s, athletes, post-illness, metabolic dysfunction)14:24 Who should skip it15:34 The three-tier dosing ladder16:54 The FDA-approved 40mg dose and diminishing returns19:08 Dosing by goal (longevity, performance, recovery, healing)19:48 Cycling logic and the 8-12 week framework20:22 When to dose (morning vs night)21:24 What to expect and when (week-by-week timeline)22:20 Why cycle if it doesn't desensitize24:24 SS-31 before MOTS-c (the structural engineer vs operations manager)26:18 Reconstitution and injection technique28:22 What to track (subjective markers and biomarkers)29:18 Stacking with MOTS-c, Humanin, BPC, GH peptides, and GLPs31:28 Stacking for cognition and visceral fat32:26 Troubleshooting "I don't feel anything"33:54 Injection site reactions34:36 When to discontinue and the first-two-week headache window35:52 FAQ (legality, MitoQ comparison, oral routes, intranasal)36:54 Use cases (weight loss, long COVID, athletic performance, TRT, kids)37:54 Research grade vs pharmaceutical cost difference38:22 Future outlook (AMD, sarcopenia, SBT-272, oral bioavailability)40:30 Final thoughts and where SS-31 sits in the broader picture42:20 Closing

Unpack the pros and cons of keto and fasting for mitochondria, and discover why the Mediterranean diet leads the pack in boosting mitochondrial health. #KetoDiet #FastingBenefits #Mitochondria #HealthTalks

Get My Myoscience Vitamin D3 + K2 - https://bit.ly/4tSrys5 

What if aging isn't a hundred separate problems but a single one — an energy crisis inside the tiny power plants of every cell? At 91, Dr. John G. Cramer is betting his own body on the answer.In this episode of Health Longevity Secrets, Robert Lufkin MD sits down with Dr. John G. Cramer — Emeritus Professor of Physics at the University of Washington and author of "How to Live Much Longer" — the oldest human on Earth to receive an experimental mitochondrial transplant. They unpack a unifying theory of aging built around damaged mitochondrial DNA, why replication errors (not just free radicals) drive most of the damage, and what it felt like to receive escalating doses of "Mitlets" — liposomes carrying fresh mitochondria harvested from young blood platelets — at a Texas right-to-try clinic.Buy Dr. Cramer's book "How to Live Much Longer": https://www.amazon.com/How-Live-Much-Longer-Cramer/dp/B0DV3ZW5T6 Cramer & Benson white paper (CBC): https://faculty.washington.edu/jcramer/Bio/CBC.pdf Mitrix Bio: https://mitrix.bio/CHAPTERS00:00 Cold open — "the oldest young human on the planet" 01:18 Meet Dr. John Cramer: physicist turned longevity pioneer at 91 03:45 Why a physicist became obsessed with aging 06:20 The unifying theory: aging as mitochondrial DNA damage 09:40 The 16,569 base pairs that run your life 13:05 Replication errors vs. free radicals — correcting Denham Harman 16:30 The damage doubling time: 12 years, then 3-4 19:50 David Sinclair's information theory of aging 23:15 James McCully and the birth of mitochondrial transplantation 27:00 "No negative results, only spectacular successes" 30:25 Mitrix Bio, Tom Benson, and the Mitlet platform 34:10 Inside Cramer's four Texas right-to-try sessions 38:30 Arm injection, belly fat, and the IV mainline that worked 42:15 What it actually feels like to receive young mitochondria 45:40 Haplogroup H2A1G1 and the Norwegian great-grandmother 48:20 The economics: scaling Mitlets to the world 51:05 Becoming the oldest young human — target age 129 54:30 What Cramer wants you to do tomorrow morning 57:00 Final reflections and where to find the bookKEY STUDIES & SOURCESCramer J.G. & Benson T. — Cellular Bioenergetic Crisis white paper: https://faculty.washington.edu/jcramer/Bio/CBC.pdfHarman D. (1972) — The biologic clock: the mitochondria?: ⭐ Enjoying the show? Please leave a 5-star review on Apple Podcasts — it takes 30 seconds and helps more people discover the science of health and longevity. Thank you!New episodes every Tuesday & Thursday. Subscribe so you don't miss one.Continue this conversation on Substack: https://robertlufkinmd.substack.comLies I Taught In Medical School — Free sample chapter: https://www.robertlufkinmd.com/lies/Web: https://www.robertlufkinmd.comYouTube: https://www.youtube.com/robertlufkinmdX: https://x.com/robertlufkinmdInstagram: https://www.instagram.com/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinLinkedIn: https://www.linkedin.com/in/robertlufkinmd/

What if the fatigue, brain fog, and loss of strength many women experience after 50 are not simply hormonal, but reflect deeper shifts in metabolism, muscle, and mitochondrial function? In this insightful episode, Dr. Elizabeth Goldspink reframes midlife as a metabolic and neurological transition rather than a purely hormonal one. She explains how muscle acts as a longevity organ, how mitochondrial efficiency impacts both energy and cognition, and how targeted lifestyle and nutrition strategies can restore resilience. This empowering conversation offers practical, science-informed steps to help women take control of how they age. Dr. Elizabeth Goldspink is a naturopathic doctor, women's health researcher, and founder of Wellex. She has more than 16 years of clinical experience supporting women's hormonal, metabolic, and immune health. Dr. Goldspink is a published author in peer-reviewed medical journals and has completed advanced training in mind-body medicine at Harvard University. Her work focuses on translating complex scientific research into practical, personalized health strategies. She has helped thousands of women restore energy, resilience, and long-term well-being. Her current focus is on evidence-based supplementation and metabolic health optimization for women in midlife and beyond. Episode Timeline 00:00 – Welcome and introduction 02:30 – Midlife symptoms reframed: beyond hormones to metabolism and mitochondria 04:00 – Dr. Goldspink's personal journey from marketing professional to naturopathic medicine 06:00 – Why brain fog, fatigue, and strength loss signal deeper biological shifts 08:00 – Muscle as a longevity organ and its role in metabolic and cognitive health 11:00 – The metabolic functions of muscle and the importance of myokines 13:30 – Resistance training and why lifting weights matters for women over 50 16:00 – Nutrition fundamentals: protein intake, glycemic stability, and whole foods 19:00 – Mitochondrial health and its connection to energy and cognition 22:00 – Practical strategies to optimize mitochondria without complex protocols 25:00 – Creatine explained: benefits for muscle, brain, and aging 29:00 – Real-world recovery and rebuilding strength after health setbacks 31:00 – Brain training, lifestyle habits, and community connection 33:00 – Managing stress, social media overload, and mental resilience 35:00 – Supplement strategy after 50: what to use and what to avoid 37:30 – Common mistakes: overuse of antioxidants and low-quality supplements 40:00 – The origin of Wellex and a mission to support underserved women's health needs 43:00 – Practical daily steps to rebuild resilience and support healthy aging 45:00 – Wrap-up and key takeaways Connect with Dr. Elizabeth Goldspink Website: https://wellex.co Science-backed supplements for women's metabolic and hormonal health Information on clinical research and product formulations Call to Action Find Growing Older Living Younger: The Science of Aging Gracefully and the Art of Retiring Comfortably at www.gillianlockitch.com (North America) or on Kindle Subscribe to Growing Older Living Younger on your favorite podcast platform and leave a review to help others discover the show. Join the Growing Older Living Younger Community  Connect with Dr. Gillian Lockitch at https://www.askdrgill.com/ or email: askdrgill@gmail.com Download Guide to Nature's Colorful Antioxidants. 2026 

In part one of this series, Dr. Katie Krulisky and Dr. Cristina Domínguez-González discuss when a neurologist should start thinking about mitochondrial disease.  Show citation: Bermejo-Guerrero L, Restrepo-Vera JL, Martin-Jimenez P, et al. Clinical Heterogeneity and Candidate Biomarkers in POLG-Related Mitochondrial Disease. Neurol Genet. 2026;12(2):e200365. Published 2026 Mar 10. doi:10.1212/NXG.0000000000200365  Show transcript:  Dr. Katie Krulisky: This is The Neurology Minute, and this will be a two-part series. I've had the pleasure of speaking with Cristina Domínguez-González from the 12th of October University Hospital and its affiliated Health Research Institute in Madrid, Spain. I'm Katie Krulisky from the University of Utah. We've just recorded a full podcast on our paper, Clinical Heterogeneity and Candidate Biomarkers and POLG-related Mitochondrial Disease, which has been published in Neurology Genetics. So for our first minute, Cristina, when should a neurologist start thinking about mitochondrial disease? Dr. Cristina Domínguez-González: Mitochondrial diseases are among the most common inherited neurological disorders. Think of them whenever you see compatible features like ptosis ophthalmoplegia, polyneuropathy, ataxia or myopathy, especially when they occur in combination. But even when these features appear in isolation, mitochondrial disease should still be part of the differential. This is particularly important because many patients do not present with a full classical picture, especially in early the disease course. In practice, this means maintaining a low threshold to consider mitochondrial disease, even in a typical presentations. Dr. Katie Krulisky: Thank you so much. And for more information on mitochondrial disease and POLG-related disorders, do listen to the full neurology podcast. Again, I'm Katie Krulisky from the University of Utah with Cristina Domínguez-González from the 12th of October University Hospital and its affiliated Health Research Institute in Madrid, Spain.   

I'm kicking off the brand-new Her Stack series — a women's health-focused series designed to break down common goals through nutrition, lifestyle, biohacking, supplements, and peptides. Today's focus is energy: why so many women feel tired, wired, depleted, or stuck in the afternoon crash cycle, and what it actually takes to rebuild energy from the foundation up. I talk about mitochondrial health, circadian rhythm, HPA axis dysregulation, postpartum and perimenopause-related energy shifts, hydration, protein, sleep, movement, peptides, and the 12-week framework I would use to start feeling like yourself again. Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. I TALK ABOUT:  01:25 - Why Her Stack is built around women's health, longevity, and four core pillars 03:05 - Why low energy is the number one complaint I hear from women 10:55 - Why postpartum and perimenopause can create major energy shifts 12:20 - Simple questions to help you assess whether your energy is actually broken 15:25 - Key data points to track, including HRV, resting heart rate, body temperature, and sleep stages 19:00 - Labs to consider when fatigue, brain fog, or hormone changes are showing up 21:40 - Why nutrition is the foundation before supplements or peptides 28:40 - Why hydration and minerals matter more than just drinking plain water 34:50 - Mitochondrial nutrients that support energy production 39:35 - Morning sunlight, blue blockers, and sleep routines for circadian health 44:50 - How grounding may support cortisol, HRV, and inflammation 45:30 - Why Zone 2 cardio and heavy lifting are essential for women's energy and longevity 53:50 - Fringe and cutting-edge biohacks, including methylene blue, hyperbaric oxygen, ketamine therapy, and EMF mitigation 59:10 - Foundational supplements for energy, cognition, and mitochondrial health 1:04:10 - Peptides for energy, inflammation, stress, mitochondria, and recovery 1:14:40 - How peptide protocols may shift across postpartum, perimenopause, menopause, and breastfeeding 1:15:50 - The 12-week energy rebuilding plan 1:20:00 - Why energy restoration requires a holistic approach, not one quick fix RESOURCES: Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. Free Peptide Masterclass for Women: Join the waitlist for the next live class. The Her Stack Planner: The first peptide tracking journal built around female biology. PRODUCTS MENTIONED IN THIS EPISODE: Peptide Serum for Women Waitlist: Early access and founder's pricing. SiPhox Health At Home Blood Testing (code: BRITTANY10) Baja Gold Salt Mineral Sea Salt (code: BIOHACKINGBRITTANY) BiOptimizers Gut & Performance Supplements (code: BIOHACKINGBRITTANY) Filter Optix Blue Light Blocking Glasses (code: BIOHACKINGBRITTANY) HigherDOSE Red Light Therapy (code: BRITTANY15)  Pulsetto Vagus Nerve Stimulation (code: BIOHACKINGBRITTANY) Kineon Red Light Therapy (code: BIOHACKINGBRITTANY) Leela Quantum Tech EMF Protection (code: BIOHACKINGBRITTANY) Defender Shield EMF Protection (code: BIOHACKINGBRITTANY) Juunaday EMF Protection Clothes For Women (code: BRITTANY) Timeline Nutrition Mitochondria Supplement (code: BIOHACKINGBRITTANY) NOVOS Longevity Supplement (code: BIOHACKINGBRITTANY) Nuchido Time+ NAD+ Supplement (code: BIOHACKINGBRITTANY) LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

The “Perfect Body” Isn't What Instagram Sold You What does the “perfect body” actually look like?In Part 2 of Coach Alex's conversation on The Samir Show, the discussion moves beyond six-packs, big biceps, and Instagram fitness into something much more useful: building a body that can serve the mission.Coach Alex explains why excessive muscle can become a liability for operators, why the best body is not necessarily the one that attracts attention, and why true fitness is about capability, endurance, resilience, and recovery.This conversation also goes deep into metabolic health, protein intake, fatigue, sleep, dad bod, belly fat, cardiovascular fitness, diabetes risk, and why so many people feel exhausted in their 30s and 40s.The big idea: your body is not just about appearance. It is an asset. It carries your mind, your mission, your work, your family, and your calling.In this episode, Coach Alex and Samir discuss:Why the “perfect agent body” does not look like an Instagram fitness modelWhy endurance and cognitive integrity matter for real-world performanceHow your body and brain are deeply integratedWhy constant fatigue may be connected to poor metabolic healthThe role of protein in muscle, energy, aging, and blood sugar regulationWhy muscle loss accelerates with age — and how weight training helps slow it downHow sleep timing, deep sleep, naps, and circadian rhythm affect energyWhy belly fat is often connected to stress, poor fitness, and energy imbalanceThe difference between fasting, time-restricted eating, and ketosisWhy cardio is not mainly about burning caloriesHow walking, weight training, and sleep can help prevent diabetes and heart diseaseIf you are tired of treating your body like a vanity project — or ignoring it altogether — this episode will help you think differently.Your body is not an idol to worship.It is not a problem to ignore.It is a stewardship.Get the Faithful Fitness 40-Day Devotional here:FaithfulFitnessDevo.comAnd check out more conversations from The Samir Show.00:00 The perfect agent body01:36 Why the CIA body would not look like Instagram fitness02:21 Hypertrophy is only one fitness adaptation03:48 The capable body: strong, fast, endurable, and mission-ready05:09 Training bodies for the job, not choosing bodies for the job06:54 Treating the body like a national security asset07:32 Why poor health affects national security08:43 Endurance and cognitive integrity09:35 Energy, fatigue, and burnout10:08 Mitochondrial dysfunction and fat-burning capacity12:01 Carbs as short-term fuel, fats as long-term fuel13:56 Why protein matters15:13 How much protein the average person may need16:20 Why minimum protein recommendations may not be optimal18:14 Plant proteins, supplements, and vegetarian considerations19:39 Why muscle mass declines with age21:09 Weight training and preserving muscle tissue22:02 Why you may wake up more tired than when you went to bed23:11 Deep sleep, sleep inertia, and inconsistent rest25:43 Why naps help some people and ruin sleep for others27:28 Busy tired vs. metabolic or hormonal problems28:41 Why medication without lifestyle change misses the root30:34 Protein, prediabetes, and blood sugar regulation32:23 Protein intake and body composition33:41 Dad bod, belly fat, and fatherhood37:05 Hormonal changes after having a baby38:42 Keto, fasting, cardio, and stubborn belly fat39:29 Fasting vs. time-restricted eating40:34 Ketosis does not always mean body-fat loss41:50 Why cardio is not mainly for burning calories42:44 Nutrient density vs. energy density45:12 Running outside vs. treadmill48:19 Early warning signs for diabetes and metabolic disease49:00 VO2 and cardiovascular fitness as missed warning signs53:06 Basic tests for diabetes and heart disease risk55:20 Why food journaling is the first intelligence report59:35 Lifestyle changes with the biggest payoff01:00:10 Start small: 15 minutes a day01:01:46 Walking, adaptation, and energy01:02:40 Sleep, stress, and disease risk01:04:30 Creatine, sleep deprivation, and recovery support If this conversation challenged the way you think about your body, start with the Faithful Fitness 40-Day Devotional.It was written to help Christians stop treating the body as either an idol to worship or a problem to ignore — and begin seeing it as a gift to steward under Christ.Get Faithful Fitness here:FaithfulFitnessDevo.comThis conversation originally took place on The Samir Show.Check out Samir's work and follow his show for more thoughtful conversations on health, mindset, and human performance https://www.youtube.com/watch?v=lST4zzD4Hcs&t=387sBecome a supporter of this podcast: https://www.spreaker.com/podcast/faithful-fitness-with-coach-alex-vanhouten--5150768/support.

Dr. Hoffman continues his conversation with Dr. Brad Currier, clinical trial manager at Timeline, a Swiss biotech company.

Urolithin A (MitoPure)--Mitophagy, Muscle Recovery, Immunity, and Skin Health: Dr. Brad Currier, clinical trial manager at Timeline, a Swiss biotech company, details urolithin A (MitoPure), a postbiotic derived from pomegranate precursors that most people cannot produce due to microbiome differences. Currier explains MitoPure's mechanism—stimulating mitophagy to recycle dysfunctional mitochondria—and reviews evidence from multiple clinical trials. He reveals a Sports Medicine study in elite male distance runners showing reduced creatine kinase and lower perceived exertion, suggesting improved recovery, plus trials in middle-aged and older adults showing improvements in strength, six-minute walk test, and VO2 max at 500 mg–1 g doses. They also cover a Nature Aging immune study reporting rejuvenation of stem-like CD8 T cells with improved mitochondrial fatty acid oxidation, ongoing research directions, supplement quality/testing for athletes, and topical urolithin A skincare trials and partnerships, including L'Oréal Lancôme.

In this video, Dr. Ruscio discusses the benefits of glutathione, the body's master antioxidant. He discusses how to boost glutathione naturally via the diet, supplements that help boost glutathione, and how to supplement with glutathione directly (including the best forms and doses of glutathione).   ✅ Start healing with us! Learn more about our virtual clinic:  https://drruscio.com/virtual-clinic/  

You are likely sacrificing long-term health for short-term gains because you're following a "get bigger" blueprint designed for a body you don't actually want. After 21 years in the trenches—from wrestling on the WWE developmental circuit to coaching at the legendary MI40 gym—Drew Donaldson realized that the massive, 275lb version of himself was a high-performance engine running on the wrong fuel. He rebuilt his entire philosophy around the GMT Framework, proving that elite recovery and gut health are the only way to stay undeniable without burning out. INSIDE THE EPISODE: The WWE Developmental Trap: Why the "just get bigger" coaching advice is a career-ending mistake for 90% of athletes. The 275lb Awakening: A raw look at the health cost of extreme size and the specific metrics Drew used to downsize while staying elite. The GMT Framework: A deep dive into the three-pillar system of Gut health, Mitochondrial efficiency, and targeted Training. Metabolic Flexibility: Why traditional "bulking" kills your ability to utilize fuel and how to fix your internal machinery. The "Third Answer": Why both the bodybuilding and biohacking worlds are currently missing the middle ground of sustainable performance. MEET THE GUEST: Drew Donaldson is a Tampa-based high-performance coach and the founder of the DDT Method. With over 15,000 hours of in-person coaching experience, Drew's journey took him from the center of the professional wrestling world to becoming a leading educator in hybrid training and cellular optimization. Today, he helps elite performers and business executives build resilient, athletic physiques by focusing on the biology of recovery rather than just the intensity of the lift. FIND DREW: Website: DDTMethod.com Instagram: @ddtmethod YouTube: @ddtmethod DDT Method Podcast: Available on Apple, Spotify, and Amazon Music Skool Community: skool.com/ddtmethod SUPPORT DAVE TATE'S TABLE TALK: Become a Channel Member: Join @eliteftsofficial FULL Crew Access: elitefts.com/join-the-crew Limited Edition Apparel: Shop Limited Edition TYAO Application: Apply Here SPONSORS & DISCOUNTS: elitefts: Get an extra 10% OFF (CODE: TABLETALK) — elitefts.com Marek Health: Get 10% OFF Your Labs (CODE: TABLETALK) — marekhealth.com/tabletalk LMNT: Free 8-count Sample Pack — drinklmnt.com/tabletalk MASS Research Review: Save 20% (CODE: ELITEFTS20) — massresearchreview.com RP Hypertrophy App: Get 10% OFF (CODE: TABLETALK) — rpstrength.com

Today, I'm pulling together some of the most impactful conversations from the last three months on the Podcast. From breaking down the pitfalls of trendy weight loss drugs to uncovering silent heart health risks, and exploring how mitochondrial transplants and trauma healing are rewriting the story of resilience, these moments have truly shifted my perspective on what it means to pursue lasting wellness. Here are the full episodes: #401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff #414: Drop Dead Healthy? Why "Fit" Women & Men Still Have Fatal Heart Attacks! l Dr. Regina Druz #419: Origin Of Disease Is Hiding In Your Cells! Doctor Reveals How To Fix It Now l Dr. Natalie Yivgi-Ohana #421: Why You Can't Hack Longevity Until You Heal Hidden Stored Trauma! l Dr. Aimie Apigian #417: Feeling Depressed? Watch This First (It Might Not Be What You Think) l Dr. Cynthia Keller l Ep  Episode Timestamps: Welcome and quarterly recap intro ... 00:00:00 Longevity is about pattern recognition, not single breakthroughs ... 00:00:41 GLP-1s require personalization, not a one-size-fits-all approach ... 00:04:25 GLP-1 hormone assessment and individualized plans ... 00:06:03 Delayed/suppressed GLP-1 function needs lifestyle changes ... 00:08:04 GLP-1 agonists enable, but don't replace, foundational health tweaks ... 00:09:06 Heart health: sick fat disease, inflammation and cardiac risk ... 00:12:30 GLP-1 and GIP peptides have powerful anti-inflammatory effects ... 00:15:35 Menopause amplifies pre-existing heart/metabolic risks ... 00:18:22 Mitochondrial transplants: emerging therapy for rare diseases ... 00:24:04 Every disease linked to—or helped by—mitochondrial function ... 00:27:00 Trauma healing is phased; start with the gentle approach ... 00:31:21 Chronic survival state rewires the nervous system ... 00:40:02 Covid's gut impact can trigger mood issues, fixed with key nutrients ... 00:50:00 Our Amazing Sponsors: Mitopure Gummies by Timeline - These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience—visit timeline.com/nat20 to get 20% off. Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT15 to start the free 15 day trial. Daily Gut Detox by Just Thrive Health – A gentle, science-backed detox powered by clinically proven immunoglobulins that bind and remove toxins while supporting your gut, immune system, and digestion—without harsh flushing or discomfort. Visit JustThriveHealth.com/NAT20 and use code NAT20 for 20% off your order, risk-free. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

This is one of the BEST interviews we've ever done on supplements and cutting-edge supplement technology... We had Dr. Scott Sherr on the podcast — a board-certified internal medicine physician who practices health optimization medicine and hyperbaric oxygen therapy. This guy KNOWS his stuff and we break down some of the most powerful compounds you can get your hands on to improve cognitive function, athletic performance, and longevity. Here's the reality... 94% of US adults are metabolically UNHEALTHY. That means your mitochondria — the powerhouses of your cells — are struggling to produce the energy you need. Dr. Sherr explains exactly why this happens, how it connects to everything from anxiety and depression to fat loss struggles, and what you can actually DO about it. We dive DEEP into methylene blue — the first drug ever registered with the FDA back in 1897 — and why it's become one of the most powerful tools for supporting mitochondrial function and energy production. But it doesn't stop there... We cover the GABAergic system and why most people are walking around GABA deficient (hello anxiety, insomnia, and mood issues), the synergy between methylene blue and red light therapy, how to use these compounds for travel, and a complete sleep optimization stack that could finally get you those 90+ Oura Ring scores. If you're tired of being tired, stressed about being stressed, or just want to understand how to actually support your body at a cellular level — this episode is a MUST listen. MAPS PPL — https://mapsppl.com (code: ppl) SPONSORS Troscriptions — https://troscriptions.com/mindpump (code: mindpump) Seed — https://seed.com/mindpump (code: 25mindpump) 00:00 — Intro 5:56 — Dr. Scott Sherr's background and health optimization medicine framework 10:42 — Strengths and weaknesses of conventional vs alternative medicine 16:34 — Why 94% of US adults are metabolically unhealthy 22:30 — The 'sympathetic spiral of doom' and why doing MORE isn't better 25:48 — Deep dive into methylene blue — history and mechanisms 35:09 — MAO inhibition, serotonin syndrome risk, and dosing protocols 42:43 — Methylene blue and red light therapy synergy 48:55 — GABA system, B3-GABA, and the TroCalm formula explained 59:58 — Complete sleep optimization stack and nighttime routine 67:30 — Cordycepin benefits and immune support protocols PEOPLE MENTIONED Dr. Scott Sherr — Guest — board-certified internal medicine physician, health optimization medicine practitioner, co-founder of Troscriptions Dr. Ted Achacoso — Founder of Troscriptions and the Health Optimization Medicine nonprofit, mentor to Dr. Sherr Alan Sherr — Dr. Sherr's father — chiropractor for 45+ years who influenced his alternative medicine philosophy Francisco Gonzalez Lima — Researcher at University of Texas Austin studying methylene blue for Alzheimer's, TBI, and stroke Thomas DeLauer — Mutual friend who uses methylene blue 2-3 times per week on high-stress days Paul Stamets — Referenced regarding mushroom knowledge and Amanita Muscaria/Santa Claus connection

What if feeling better didn't have to take months or years to figure out, but could start today? On this episode of The Dr. Hyman Show, I sit down with Dr. Scott Sherr to talk about why so many people feel stuck in what he calls a “sympathetic spiral of doom.” Energy is low, recovery isn't what it used to be, and there's a constant sense of stress that doesn't seem to resolve. We walk through what's actually happening beneath the surface, why it can be so hard to break out of that pattern once you're in it, and how to start shifting your energy and recovery. Watch the full conversation on YouTube, or listen wherever you get your podcasts. In this episode, we discuss: • Why you feel “tired but wired” and what it actually means for your body • What's keeping your energy low even when nothing obvious is wrong • How stress from your life and environment builds up and keeps you stuck • Why calming down doesn't always work—and what to focus on instead • How to start rebuilding your energy so your body can recover and adapt We shouldn't have to wait for something to go wrong to take action. The goal is to help your body function better so you can actually feel it day to day. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Perfect Amino, Korrus, Timeline, BON CHARGE, BIOptimizers and Pique. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Visit korrus.com/drhyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Secure 20% off your order plus a free starter kit at piquelife.com/hyman. (0:00) Introduction and guest Dr. Scott Scherer (3:31) Understanding the sympathetic spiral of doom (5:06) Symptoms and signs of sympathetic overdrive (7:10) Sympathetic activation, mitochondrial function, and stress (10:02) Mitochondria: their role and impact in the body (12:31) Stress, metabolic dysfunction, and their effects (17:43) Nervous system, mitochondria, and the cell danger response (21:25) Survival, stress, and breaking the sympathetic spiral (23:11) Contributors to stress: top-down and bottom-up (25:56) Mitochondria, microbiome, and medication impacts (29:38) Mitochondrial dysfunction and mental health (32:19) Limitations of parasympathetic activation and addressing root causes (36:46) How mitochondrial stress leads to fight-or-flight (37:52) Steps to break the sympathetic spiral and support mitochondria (42:41) Methylene blue: benefits, uses, and safety (50:35) Methylene blue as an MAO inhibitor and for chronic infections (57:17) Case studies, third-party testing, and Transcriptions' evolution (1:02:36) Parasympathetic edge, recovery, and the GABA system (1:07:44) GABA, supplements, and interventions for stress (1:12:23) Addressing root causes and methylene blue usage (1:17:29) Transcriptions products, sleep formula, and practitioner ecosystem (1:19:49) OneBase Health, hyperbaric space, and final information

If you're doing everything “right”—eating well, taking supplements, working on your health—but still feel stuck, this might be the missing piece. Your body cannot heal if it thinks it's under threat. In this episode, we unpack why your nervous system may be the hidden driver behind inflammation, hormone imbalance, weight gain, and more—and how to finally shift your body into healing mode. Here's what could be keeping you stuck: • Why chronic stress and nervous system dysregulation can block healing—even when everything else is “on point” • How your nervous system impacts your gut, hormones, metabolism, immune system, and weight • The difference between feeling “tired but wired” vs. true resilience and what a regulated system actually looks like • Simple, science-backed ways to regulate your nervous system through blood sugar, breath, sleep, and daily habits You can't out-supplement or out-diet a body that feels unsafe. But when you learn how to regulate your nervous system, you unlock your body's natural ability to repair, rebalance, and heal. Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year. Have a question you'd love answered on Office Hours? Submit it here   (0:00) Nervous system regulation, chronic stress, and healing (2:21) Simplifying the nervous system and resilience (4:06) Signs and effects of nervous system dysregulation (6:24) Characteristics of a regulated nervous system (7:39) Practical tips for nervous system regulation (10:09) Building muscle, improving sleep, and myths about regulation (12:20) Upcoming episode and sympathetic activation (14:09) Mitochondrial dysfunction and importance in health (18:37) Closing remarks and call to action

Welcome to this week's Midlife Minute episode. Today, I respond to a complex question from my free Facebook group.  Stay tuned as I explore the root cause of Melinda's persistent knee inflammation, from protein needs and recovery to mitochondrial support, and why eating “clean” does not always reduce inflammation. IN THIS EPISODE, YOU WILL LEARN: How persistent swelling and discomfort after 40 could reflect mitochondrial decline Why 20 to 25 grams of protein at a meal may not be enough to trigger muscle protein synthesis Why eating “really clean” while doing heavy exercise could create a relative energy deficiency Mitochondrial support supplements that are commonly used for repair and boosting mitophagy The benefits of the flavonoid, apigenin The value of CoQ10, especially for those on statin therapy Why melatonin is more than just a sleep hormone How BPC 157 differs from the experimental peptides available online Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Link: Troscriptions  - https://troscriptions.com/discount/CYNTHIA10

If you want to get leaner and live longer check out https://milliondollarbodylabs.com Have you ever been sidelined by an injury and wondered if there was a way to bypass the "Netflix and chill" recovery method to heal 30% faster?   I put together a compilation to show how to bulletproof your body. I talk with Michael Roviello about baths and fat. He explains how therapy helps mitochondria. Gary Brecka discusses how oxygen prevents disease and warns against the pathway of injuries. I explain how restriction training triggers hormones. I demonstrate using bands for compression to flush waste and I also detail using a ball to release spasms. These methods help you recover from surgery or pain without relying on ibuprofen. Key Takeaways Ice baths trigger a nervous system shift that reduces inflammation and can induce a meditative state through theta brainwaves. Brown fat acts as a thermogenesis process that converts visceral fat into heat when the body is exposed to cold environments. Mitochondrial function is the core of optimal health, and it can be improved through red light therapy and cold shock proteins. Blood Flow Restriction (BFR) training can speed up recovery by 30% by inducing a hormonal cascade of HGH and IGF-1. The presence of oxygen is the absence of disease, as hypoxia is at the root of nearly every major health issue. Voodoo bands provide mechanical compression to flush out waste products and reestablish full range of motion in joints. Contrast therapy creates a "pump effect" in blood vessels by alternating between hot and cold to move nutrients to injured areas. Resources  Nate Palmer: The founder of The Million Dollar Body and author of "The Million Dollar Body Method", Nate has been coaching for over 15 years and has worked personally with over 1,000 clients.   Website: https://milliondollarbodylabs.com Book: The Million Dollar Body Method Lean Energy Stack: https://milliondollarbodylabs.com/pages/lean Instagram: @_milliondollarbody

Episode 2777 - Vinnie Tortorich speaks to nurse practitioner Cynthia Thurlow about her upcoming book and the importance of optimizing your gut. https://vinnietortorich.com/2026/03/optimizing-your-gut-cynthia-thurlow-episode-2777 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout Optimizing Your Gut Cynthia Thurlow is a nurse practitioner and has her own podcast, "Everyday Wellness," which focuses on women's health. (2:00) She has a book coming out, "The Menopause Gut," scheduled for release in late April 2026. You can go directly to her website and pre-order it. https://www.cynthiathurlow.com GLP1s can be helpful for morbidly obese people, but people who are not obese shouldn't be on them. Recent photos of certain celebrities show muscle wasting, which can lead to being fragile and long-term damage. Vinnie has concerns about GLP1s over the long term. What are some definitions of perimenopause, menopause, and post menopause? (27:30) The gut is important for hormonal health because it helps break down hormones for use in the body. Vinnie shares a story about his Mom and why the idea of hormones doesn't always sit well with him. (32:00) There is a difference between birth control pills and the bioidentical hormones of today. Hormones play a significant role in multiple organ systems, including the heart, bones, and brain. Is testosterone replacement necessary for men or women? (44:00) You still have to lead a healthy lifestyle; hormone replacement isn't a band-aid for a bad lifestyle. Mitochondrial health also plays a big role. (49:00) Sleep is foundational to your metabolic health as well. (54:00) Vinnie asks about DHEA and whether supplementation is beneficial. (57:00) What are things we can optimize for our health as we enter perimenopause and andropause? (1:04:00) Fiber from food is helpful for the gut for various reasons. Cynthia shares cautionary tales about being a long-term carnivore. (1:10:00) They discuss certain food addictions, especially to sugar and sweeteners. (1:13:00) A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $300 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. (1:05:00) You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries