Podcasts about ddw

The latest episode of the DDW Highlights Podcast is now available to listen to below. DDW's Bruno Quinney narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In this week's news, results from a clinical trial offer hope for the first time that Huntington's disease can be slowed. Elsewhere, new synthetic kidneys could be 'revolutionary' tools for kidney disease research, and pharma giant Merck has partnered with technology company Siemens to develop AI projects. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In this week's episode of The Energy Code, Dr. Mike Belkowski sits down with Victor Sagalovsky, co-founder of Litewater Scientific, to explore one of the most cutting-edge frontiers in mitochondrial optimization: deuterium depleted water (DDW). Victor, a longtime water researcher and pioneer in bringing ultra-low deuterium water to the world, shares how this overlooked isotope may hold the key to boosting energy production, extending healthspan, and even influencing genetic expression.   Expect a mix of quantum biology, practical lifestyle strategies, and a deep dive into the physics of water as Dr. Mike and Victor decode how lowering deuterium levels impacts mitochondrial health and human longevity. Key Topics Covered Victor's Origin Story – How a lifelong fascination with water led him to co-found Litewater Scientific and make deuterium depleted water accessible . What is Deuterium? – Breaking down the isotopes of hydrogen and why deuterium disrupts mitochondrial ATP synthase, causing “stutters” in energy production. The Mitochondrial Connection – How excess deuterium damages membranes, reduces proton motive force, and accelerates aging. Deuterium & Disease – The striking links between high deuterium levels, cancer risk, and neurodegeneration. Thresholds for Health – Why 120 ppm is considered the metabolic “line in the sand,” and how most modern water supplies far exceed this. How DDW is Made – The massive proprietary columns and energy-intensive process behind creating 10 ppm and 5 ppm light water. Psychological & Cognitive Benefits – Correlations between lower deuterium levels and improved mood, optimism, and confidence. Lifestyle Strategies – Beyond DDW: fasting, ketogenic diets, hydrogen inhalation, and limiting overconsumption of food and water. Practical Outcomes – How listeners can begin to measure, lower, and optimize their own deuterium levels for energy and longevity. Key Quotes   Victor Sagalovsky: “Every eight seconds, an ATP synthase stutters because of deuterium—it's the kiss and the elbow at the same time.” “Our physiology is designed for about 120 ppm of deuterium, but most people are sitting at 150 or higher—that's the metabolic danger zone.” “When you deplete deuterium, your body thanks you. You feel lighter, both metaphorically and literally.”   Dr. Mike Belkowski: “When I first tried Litewater, I felt an immediate pull—like my cells wanted more. It was magnetizing.” “The implications for cognition, mood, and even neurodegeneration are massive when you consider how mitochondrial dense the brain is.” Episode Timeline   00:00 – Introduction & the promise of radical life extension   01:30 – Dr. Mike introduces Victor and Litewater Scientific   04:00 – Victor's background as a water researcher and discovery of DDW   07:00 – Why deuterium is the hidden disruptor in energy production   12:00 – How ATP synthase “stutters” under deuterium load   18:00 – Membrane damage, proton leakage, and mitochondrial shutdown   24:00 – Cognitive, emotional, and energetic effects of lowering deuterium   32:00 – The massive engineering challenge of producing ultra-low deuterium water   39:00 – Deuterium and cancer risk: research, case studies, and suppression   46:00 – The “line in the sand” for ppm and metabolic safety   55:00 – Lifestyle strategies: fasting, keto, hydrogen inhalation, and exercise   01:00:00 – Testing, tracking, and maintaining optimal deuterium levels   01:03:00 – Closing thoughts on energy, freedom, and future of water Resources & References Litewater Scientific Book: Deuterium Depletion: A New Strategy in Cancer Therapy - Dr. Gabor Somlyai Dr. Zoltán Nagy – Research on ATP synthase stutter and deuterium's role Deuterium Depletion Resource Hub

The latest episode of the DDW Highlights Podcast is now available to listen to below. DDW's Bruno Quinney narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In this week's news, AstraZeneca has halted its £200 million research investment in the UK. Elsewhere, the US Food and Drug Administration (FDA) has fast-tracked a gene therapy, CAR-T therapy could be an effective cancer treatment, and the National Institute for Health and Care Excellence (NICE) has updated its thresholds for ultra-rare disease drugs. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

Could the water you drink impact your gut health? In this episode, Dr. Greg Nigh discusses deuterium-depleted water, sulfur metabolism and hydrogen sulfide SIBO and their relationship with digestion, energy and overall health. You'll also hear practical insights on ketogenic and carnivore diets, plus emerging therapies like peptides and infrared light. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes

Censored on YT within hours! Find the video format on Bitchute.I am so happy to welcome back George Wiseman for another in-depth conversation about Brown's gas, its health benefits, and the science behind this therapy. Our first conversation is episode #88, so be sure to listen to that episode for the full background on how it all got started and the science behind it.Our discussion today covers practical tips for using Brown's gas machines, personal and listener testimonials, the latest research on Brown's Gas's impact on the body, and comparisons with other therapies like ozone.You will also hear about new product developments, water science, and answers to common questions from the community.Whether you're new to Brown's gas or looking for advanced insights, this episode packs a punch!Here's what is covered:01:00 – Inro for George and recap of previous episode01:22 – Recap of George's background, inspiration, and the origins of the Brown's gas technology.02:30 – What is Brown's gas? Why should people care? Explanation of hydrogen, oxygen, and electrically expanded water.03:14 – George shares personal health improvements from using Brown's gas, including pain relief and weight loss.05:45 – Discussion on the therapeutic effects of Brown's gas and its impact on the body.07:17 – The role of hydrogen in the microbiome and scientific studies from Asia.11:35 – My own personal experience with the machine.13:37 – Safety considerations for inhaling hydrogen and how to set the machine for different users.16:44 – Bubbling water with Brown's gas: how long to bubble, what the residue is, and the science behind it.19:59 – The importance of “easy gel” (exclusion zone water) and its health implications.22:44 – How Brown's gas expands the easy gel and why that's beneficial.25:54 – More on the science of water, capillaries, and how trees and bodies move fluids.28:00 – The impact of Brown's gas on stem cells and skin regeneration.31:21 – Testimonials and studies on Brown's gas for healing, including scars and post-surgery recovery.34:59 – Using Brown's gas for topical treatments and specific conditions like arthritis and tendonitis.38:43 – Research and testimonials on Brown's gas for lung health, allergies, and respiratory conditions.41:00 – Microbubbler attachment: what it is, how it works, and its benefits for bathing.46:08 – Deuterium depleted water (DDW): what it is, why it matters, and how the technology is developing.51:11 – The memory of water, experiments, and the importance of using healthy materials in water apparatus.55:54 – Comparing Brown's gas and ozone therapy: differences, benefits, and how to use them together safely.1:00:58 – Brain health, mood, and neurological benefits of Brown's gas. Testimonials on dementia, Parkinson's, and depression.1:08:00 – Using Brown's gas for athletes and performance enhancement.1:10:00 – Addressing anxiety and depression with Brown's gas. Personal stories and international medical perspectives.1:14:00 – Topical use, water memory, and how long hydrogen stays in water for treatments.1:18:00 – Using frequencies with the machine and their potential health effects.1:22:00 – Eye health and using Brown's gas goggles. Safety tips and user experiences.1:27:00 – Cleaning and maintaining the machine, understanding yellow water, and topping up the solution.1:32:00 – Structuring water, hydrogen peroxide, and other oxidative therapies.1:36:00 – Brown's gas as a tool for mitigating circulatory and cardiovascular issues.1:40:00 – How to find more information: eagle-research.com, discount code TSC 50, and what's available on the website.1:44:00 – Manufacturing in Canada, shipping details for Canadian customers, and final thoughts.That's a lot!If you enjoyed this episode, please share if you dare and consider going to www.sovereigncollective.org/shop to check out my offerings and get a deal while supporting the podcast. I'll be adding more great offerings there over time.To save 5% on your purchase of an Aqua Cure machine use code TSC50 and learn all about George and his offerings at:https://eagle-research.com/product/ac50/---------------------------------------------------------Are you concerned about the future of our children?The world needs more conscious parents. Stop raising children who need to recover from their childhoods! Get your online program chock full of interviews with world renowned experts here:http://www.sovereigncollective.org/gettheguideEmail me: sascha at sovereigncollective dot org

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Emma Johnson, CEO of Essential Pharma, about the company's move into clinical development, with the acquisition of Renaissance Pharma's immunotherapy asset in development for the treatment of high-risk neuroblastoma in children.  You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Joel Stanley, CEO of Ajna Biosciences. We explore the promise and challenges of botanical drugs, focusing on Ajna Biosciences' approach to developing therapeutics derived from plants such as cannabinoids and psychedelics. Joel reflects on his experience co-founding Charlotte's Web during the early medical cannabis movement and how that shaped his perspective on botanical drug development. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The news this week has emphasised the importance of shared knowledge and expertise to the development of new drugs, whether that is through research collaboration agreements or mergers and acquisitions, with a number of new deals across different therapy areas. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “Strategies and challenges in therapeutic development and lab practice”, which covers three articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “The inner workings of antibiotics”, “Targeting advances in immunotherapies”, and “The considerations for building sustainable labs in pharma”. In the first article, Dr Luke Clifton, Instrument Scientist at ISIS Neutron and Muon Source, explains the molecular mechanism behind antibiotics. In the second article, DDW Editor Reece Armstrong speaks to Christian Leisner, Chief Executive Officer of antibody therapeutics' developer CDR-Life about methods to increase access to antigens and improving immunotherapy treatments. In the third article, DDW Editor Reece Armstrong speaks to Will Fogden, UK Development Manager, Kadans Science Partner, about sustainable efforts in pharma and the considerations industry needs to take into account when developing sustainable buildings.

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In the week that the US Department of Health and Human Services cancelled multiple contracts investigating mRNA vaccines, a number of other clinical trials have made the headlines.  You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week has seen some incredible advances in immunotherapy, including the development of a therapy that combines natural killer and CAR-T cells, and an off-the-shelf cancer vaccine that could revolutionise treatment for patients with one of the most common cancer-driving mutations. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Steve Ruston, CEO of Persica Pharmaceuticals. Ruston has been CEO since the company was founded and has been a key player in developing Persica's non-opioid, one-off treatment. In this episode, we discuss the shift toward treating bacterial causes of chronic low back pain, the use of MRI biomarkers in trials, the evolving role of non-opioid therapies amid the opioid crisis, and how Persica's scientific insights and early trial success could drive renewed investment in a historically challenging field. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With the Alzheimer's Association International Conference (AAIC) taking place this week in Toronto, Canada, there have been a number of updates in the neuroscience drug discovery field. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Following the recent news that the FDA rejected Ultragenyx Pharmaceutical's gene therapy due to manufacturing concerns, manufacturing has dominated the headlines this week, particularly significant investment in facilities in the US, and new guidelines to speed up CGT production in the UK. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Thijs Spoor, CEO of the radiopharma company Perspective Therapeutics. The conversation covers how Perspective is advancing alpha-emitting radiopharmaceuticals to transform cancer treatment, with Spoor discussing the scientific, regulatory, and commercial challenges shaping the future of personalised oncology. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week's news highlights reflect the incredible levels of innovation and investment, but also the hurdles to overcome, in developing gene therapies – breakthrough treatments in many genetic diseases that can bring their own unique challenges in terms of manufacturing, delivery and safety risks. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “Innovative applications of AI in drug discovery”, which covers two articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “Decoding diseases: The AI renaissance in clinical trials” and “Advancing antibody discovery with AI”.  In the first article, Deepika Khedekar, Associate Centralized Clinical Lead at IQVIA, explains how artificial intelligence could make clinical trials more accurate, accessible and standardised. In the second article, DDW Editor Reece Armstrong, speaks to Kashif Sadiq, Founder of DenovAI Biotech about the importance of computational methods in this field.

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week our news highlights focus on the drug discovery in the European Union, including some new regulatory approvals from the European Commission, advancements from Netherlands-based argenx, a new PhD programme in Estonia, and Switzerland's evolution as a deep tech leader. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In this episode, Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGH​, discusses the most recent developments in primary biliary cholangitis (PBC) treatment, including cutting-edge data on new and emerging agents and how these updates may be integrated into your practice. Topics include:Steatotic liver disease and PBCVibration-controlled transient elastography (VCTE) and discordant biochemical responses in PBCPPAR agonists and IBATs for PBC treatment Presenter:Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGHAssociate ProfessorNIHR Birmingham BRCUniversity of BirminghamConsultant Hepatologist, Liver UnitUniversity Hospitals BirminghamBirmingham, United Kingdom Link to full program: https://bit.ly/44ySoL3Follow along with the slides: https://bit.ly/3IvwQrjGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

In this episode, Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGH​, discusses the most recent developments in primary biliary cholangitis (PBC) treatment, including cutting-edge data on new and emerging agents and how these updates may be integrated into your practice. Topics include:Steatotic liver disease and PBCVibration-controlled transient elastography (VCTE) and discordant biochemical responses in PBCPPAR agonists and IBATs for PBC treatment Presenter:Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGHAssociate ProfessorNIHR Birmingham BRCUniversity of BirminghamConsultant Hepatologist, Liver UnitUniversity Hospitals BirminghamBirmingham, United Kingdom Link to full program: https://bit.ly/4lKaO2HFollow along with the slides: https://bit.ly/44PPBysGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In significant news this week, the FDA in the US has removed red tape that limits which centres could give CAR-T therapy, in a move to improve access to the therapies. The round-up this time focuses on other developments in cell and gene therapies (CGT) including two high profile acquisitions. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

Artificial intelligence (AI) and big data are revolutionizing industries—so why is dairy only now catching up? In this episode, we explore: Why the dairy value chain is embracing AI nowHow DDW is using data to support smarter, more sustainable dairy operationsThe journey from raw farm data to actionable AI insights Don't miss this conversation on the future of dairy tech! This episode is sponsored by Dairy Data Warehouse.  At Dairy Data Warehouse (DDW), we unlock the full potential of data on dairy farms across the globe to enable the industry to harness big data and AI for sustainable and more profitable farming. DDW collects farm data from the herd management software and other sources on farm. We ensure high data quality by cleaning and transforming it into a unified, comparable set for AI driven strategic decision-making, benchmarking and insights. Our solutions support key stakeholders in nutrition, genetics, animal health, cow monitoring, and milking equipment. Let's connect to explore how data can drive your business forward.

This is the latest episode of the free DDW narrated podcast, titled "UK Spotlight: Innovation and discovery”, which covers three articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “Where is the drug discovery expertise happening in the UK?”, “From the top: Dr Martin Main, Medicines Discovery Catapult”, and “Meet the Researcher: Molly Stevens, Oxford University and Imperial”. In the first article, I highlight the research taking place and where this is happening in the UK, a long-established hub for drug discovery expertise worldwide.  In the second article, I spoke with Dr Martin Main, Chief Scientific Officer, Medicines Discovery Catapult, in the From the Top series.   In the third article, I spoke with Molly Stevens, John Black Professor at Oxford University and Research Director for Biomedical Materials at Imperial College London, as part of the Meet the Researcher series.

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. As we announce the DDW ‘Creating cures' programme at SLAS2026, the week's news highlights emphasise the importance of advanced technologies to the success of drug discovery, including digital control arms for clinical studies, nanobody-based imaging, and new applications for artificial intelligence (AI). You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Professor Jonathan Kagan, a Harvard immunology professor and director of Basic Research at Boston Children's Hospital. He's also the founder of Corner Therapeutics, a biotech startup launched this year with $54 million in funding to develop revolutionary vaccines designed to tackle a virtually unlimited range of diseases, including cancer, HIV, and Covid. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In the same week DDW shared expert insights from the 2025 ASCO annual meeting, there have been several significant developments in oncology drug discovery, including new therapy options for some difficult to treat cancers. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week's round-up highlights the vital role of genetics in drug discovery, including new data for an Alzheimer's gene therapy, the discovery of a genetic target for rejuvenation therapies, and a 13-year follow up on haemophilia gene therapy patients. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “Innovative uses for biomarkers in drug discovery”, which covers three articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “Advances in neuroscience drug discovery”, “Putting human data at the centre of drug discovery”, and “The era of precision neuroscience”. In the first article, Lu Rahman looks at neuroscience drug discovery – advances and challenges – and how breakthroughs in this field are helping address areas of unmet need. In the second article, James Peach, Co-Founder and CEO of Human Centric Drug Discovery (HCDD), an Oxford University spin-out improving neurology drug discovery by bringing more human data to the process, shares insight with me.  In the third article, Dr Steve Gardner, CEO of the computational biology company PrecisionLife, explores the challenges of achieving precision medicine in complex CNS conditions and explains how new precision neuroscience approaches are benefitting pharmaceutical companies who are again investing in the field to develop better treatments for neurological and neuropsychiatric diseases.

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With conference season in full swing and the speakers announced for DDW's Turning Science into Business Symposium in November, our news round-up shines a light on the importance of these in-person events for sharing and discovering the latest drug discovery breakthroughs. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Dr Emil Lou, Professor of Hematology and Oncology at the University of Minnesota. They discuss the promising results of a recent clinical trial he led focused on gastrointestinal cancers, the potential impact of continued clinical success on the future of these hard-to-treat cancers, and the key challenges that must be addressed to sustain progress. Dr Lou also explores the evolving role of multiplexed gene editing in tackling immunosuppressive or heterogeneous solid tumours, the complexities of forging academia-industry partnerships to support early-phase innovation, and the scientific breakthroughs he believes will shape the next five years in cancer research. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. News stories of note for this week include a major deal signed between Eli Lilly and Rznomics in the field of RNA-editing therapies, and a potential quality-of-life breakthrough for patients with Parkinson's. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “Innovative uses for biomarkers in drug discovery”, which covers two articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “How biomarkers can help discover new treatments for women's health” and “Could NfL accelerate drug development for neurodegenerative diseases?” In the first article, DDW Editor Reece Armstrong speaks to Dr Steve Gardner, Co-Founder and CEO of PrecisionLife about work the company is doing to improve our understanding of endometriosis. In the second article, Professor Andy Whiting and Dr Tony Lockett discuss how specific levels of a protein could be used to advance drug development in neurodegenerative diseases.

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Our news highlights this week focus on drug discovery for metabolic diseases, with a number of developments in treatments for obesity, liver disease, and diabetes. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Phil L'Huillier, CEO of Scancell. Following the company's recent partnership with the NHS Cancer Vaccine Launch Pad, enabling fast-tracked access for melanoma patients, we discuss how Scancell is addressing the scientific, clinical, and logistical challenges of developing therapeutic cancer vaccines—from overcoming tumour heterogeneity and improving immune response to leveraging national infrastructure like the NHS Cancer Vaccine Launch Pad to enable broader, more inclusive trial access. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Our news highlights this time focus on two major regulatory agencies, in a week that saw the European Commission (EC) launch a new fund designed to tempt US researchers to EU countries, and the US Food and Drugs Administration (FDA) roll out extensive new AI systems. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “Cutting-edge tools shaping early-stage drug discovery”, which covers three articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “The use-case for NGS”, “Are organ-chips the future of preclinical research?” and “What spatial biology can tell us about disease and drug discovery”. In the first article, DDW Editor Reece Armstrong speaks to Dr Darrell Green, Lecturer in RNA Biology, Biomedical Research Centre, Norwich Medical School University of East Anglia, about his work using next generation sequencing (NGS) and the areas the technology is impacting within drug discovery and development. In the second article, Diana Spencer catches up with Lorna Ewart, PhD, Chief Scientific Officer of Emulate, about the rise of organ-on-a-chip technology. In the third article, DDW Editor Reece Armstrong speaks to Benedikt Nilges, Head of Technology and Data Analytics at OMAPiX about spatial biology's use in drug discovery and bettering our understanding of disease.

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Our highlights this week demonstrate a variety of approaches to cancer treatment, including a BTK inhibitor, macrophage checkpoint inhibitor, and antibody-drug conjugates, at various stages of development. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.    In this episode, Megan Thomas is in conversation with Dimitrios Goundis, CEO of Kither Biotech. Kither is a Phase I, soon to be Phase II, Italian biotech focused on respiratory diseases such as cystic fibrosis. This episode explores how emerging biotech strategies are advancing treatments for respiratory diseases like cystic fibrosis, with a focus on targeted drug delivery, clinical trial progression, and the evolving biotech landscape in Europe. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

The latest episode of the DDW Highlights podcast is now available. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With the American Association of Cancer Research (AACR) Annual Meeting taking place from 25-30 April, the DDW news desk has been inundated with the latest advances in cancer drug discovery, so here are a few highlights. Check out our round-up for the event for more updates. You can listen here, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “An overview on the impact of synthetic biology”, which covers two articles written for DDW Volume 24 – Issue 3, Summer 2023. They are called: “Synthetic biology: Impacting drug discovery” and “Synthetic biology: Innovating in drug discovery” In the first article, Mark Kotter, Founder and CEO of bit.bio, talks with Reece Armstrong about different approaches to synthetic biology and its applications in programming stem cells into mature, functional human cells for drug discovery and the creation of next generation. In the second article, Reece Armstrong examines recent activity within the synthetic biology sector and highlights some of the key advancements and innovation.

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. With Eli Lilly so far winning the race to bring an oral GLP-1 drug to market, having announced positive topline results from a Phase III trial, this week our news highlights focus on clinical studies. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “Where are scientists making waves in drug discovery?”, which covers three articles written for DDW Volume 24 – Issue 3, Summer 2023. They are called: “How pharma is targeting advances in Alzheimer's treatments”, “The start-up disrupting the field of women's reproductive health” and “India: Why is the country ramping up drug discovery research?” Cognition Therapeutics recently completed the enrolment of its Phase II SEQUEL trial for patients with mild-to-moderate Alzheimer's disease. The focus of the trial is to test Cognition Therapeutics' experimental drug, CT1812 for patients with dementia with Lewy Bodies and dry age-related macular degeneration. In the first article, Reece Armstrong speaks to Lisa Ricciardi, CEO of Cognition Therapeutics, to learn about what the company hopes to achieve with CT1812. In the second article, DDW's Diana Spencer speaks to Alok Javali, CSO of dawn-bio, a new addition to BioInnovation Institute's (BII) Venture Lab acceleration programme, about the lack of innovation in women's reproductive health and the company's plans to fill the vacuum. In the third article, I take a deeper look into why India is ramping up drug discovery research, and explores the country's innovation hubs of interest.

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. In a week of financial uncertainty for the industry, our round-up focuses on the power of partnership to accelerate drug discovery, from the prevention of respiratory infections, to mapping gene activity in inflammatory bowel disease. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “Innovation enabled by new drug discovery technologies”, which covers two articles written for DDW Volume 24 – Issue 3, Summer 2023. They are called: “Accelerating biotherapy and personalised medicine with long DNA” and “The microbiome in precision medicine”. In the first article, Matt Hill, Founder and CEO of Elegen writes about the importance of innovation in DNA synthesis to address critical bottlenecks in biotherapy development. In the second article, Katie Gillette, Senior Project Leader, Eliza French, Analyst, and Graham Friedman, Analyst, DeciBio, provide an industry overview of the role of the microbiome in precision medicine, and its interplay with research tools, diagnostics, and therapeutic development.

This is the latest episode of the free DDW narrated podcast, titled “Innovation enabled by new drug discovery technologies”, which covers three articles written for DDW Volume 24 – Issue 3, Summer 2023. They are called: “Sitting down with… Neil Dhawan”, “Meet the researcher: Giusy Di Conza, iOnctura” and “From the Top: Adele Hannigan, Antibody Analytics”. In the first article, Reece Armstrong speaks to Neil Dhawan, the Co-founder and CEO of Totus Medicines about the company's approach to drug discovery using fundamental technologies in chemistry, biology and artificial intelligence (AI). In the second article, Megan Thomas looked at a day in the life of Giusy Di Conza, Head of Research at iOnctura. In the third article, Megan Thomas shines a spotlight on Adele Hannigan, CBO for Antibody Analytics, which has since been rebranded as RoukenBio.

This is the latest episode of the free DDW narrated podcast, titled “Innovation enabled by new drug discovery technologies”, which covers two articles written for DDW Volume 24 – Issue 3, Summer 2023. They are called: “Finding the North Star of therapeutic antibodies” and “Which diseases will benefit from therapeutic antibody development?” In the first article, Katie Abouzahr is the Vice President, Autoantibody Portfolio and Maternal Fetal Disease Area Leader at the Janssen Pharmaceutical Companies of Johnson & Johnson. She speaks with Megan Thomas about the future for Janssen's investigational medicine nipocalimab and antibody therapeutics at large. In the second article, DDW's Megan Thomas looks at how different diseases will benefit from the success of therapeutic antibodies.

We talk with Sam Williams of Ultimate Derby and the one and only Chris Deflorian of DDW about the first show struggles at Madison, for a little more in depth take on the show. Hope you enjoy the listen

The latest episode of the DDW Highlights podcast is now available to listen. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. Weight loss drugs have been making the news this week. As we come to the end of Women's History Month, two of the covered studies focus on women's health, specifically the role of weight loss drugs in treating endometriosis and why women have worse side effects from these therapeutics.  You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts. 

This is the latest episode of the free DDW narrated podcast, titled “Innovation enabled by new drug discovery technologies”, which covers two articles written for DDW Volume 24 – Issue 3, Summer 2023. They are called: “CRISPR breakthroughs: New solutions for common diseases” and “Re-assessing the risks of drug-induced arrhythmias during drug discovery”.  In the first article, Rolf Turk, Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. In the second article, Dr Mark Treherne, Dr Jack Scannell and Dr Richard Saumarez answer the question: Can potentially lethal arrhythmias induced by novel drugs be better predicted by using more relevant and sophisticated electrophysiological screening methods?

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW's Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. This week the DDW news round-up takes a look at developments in cancer research, including AZ's acquisition of EsoBiotec, positive trial results for an allogeneic T-cell therapy, and a new drug target for glioblastoma. You can listen below, or find The Drug Discovery World Podcast on Spotify, Google Play and Apple Podcasts.