Podcasts about microbetv

In his weekly clinical update, Dr. Griffin briefly discusses the E.coli outbreak associated with onions from McDonald's before deep diving into the announcement of Robert F Kennedy Jr. nomination for Secretary of Human and Health Services with highlights from MicrobeTV's own Vincent Racaniello and Paul Offit (Beyond the Noise), the global measles outbreak, underutilization of influenza antivirals for children and teens, the $350 million 2025 order for mpox vaccination, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, the effectiveness of N95 mask, the interplay between transmission and immunity for virus spread, where to find PEMGARDA, and translational science being conducted to understand long COVID including ongoing clinical trials, development of animal models and how sex may affect outcomes. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Micky D's onions linked to E. coli outbreak….another reason to not eat fast food (CDC) RFK Jr. series…..does he get anything right? (FactCheck.org) Salk polio vaccine : a calculated risk? (BMJ) How to conduct a controlled vaccine trial (American Journal Public Health Nations Health) Safety and efficacy of BNT162b2 mRNA COVID-19 vaccine (NEJM) Another Safety and efficacy study: mRNA-1273 SARS-CoV-2 vaccine (NEJM) …..SERIOUSLY! can't RFK Jr get it correct? (FactCheck.org) ‘I've Come Home Today': RFK Jr. (the Defenders Children's Health Defense News & Views) Thank God for sensible people: Racaniello and Offit (microbeTV) RFK Jr. : MAN CAN'T YOU GET ANYTHING RIGHT? (Annenberg Public Policy Center: University of Pennsylvania) No harm in repeating Vinny! Thank God for sensible people: Racaniello and Offit (microbeTV) Did America think Trump-Kennedy through? …..really did you think this through? (microbeTV) Make American Healthy Again? ……I will have fries with that….SUPERSIZED! (Wall Street Journal) Keep the United States HEALTHY! (Safe Communities Coalition) Measles in the US (CDC Measles: Rubeola) The merry-go-around of measles (JID) It is a measles outbreak! (CDC Measles: Rubeola) 10.3 million measles infections in 2023….but no vaccine (WHO) Underutilization of influenza antiviral treatment among children and adolescents (CDC MMWR) Increase in influenza infection in children…..(CIDRAP) Influenza weekly surveillance report: clift notes (CDC FluView) $340 million doses of mpox vaccine ordered for 2025 (Reuters) Mpox in NYC (JID) Respiratory virus activity (CDC Respiratory Illnesses) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) N95 Filtering Facepiece Respirator use (JAMA Open Network) The Risk of SARS-CoV-2 Transmission in Community Indoor Settings (JID) Lower levels of household transmission of SARS-CoV-2 VOC Omicron compared to Wild-type: an interplay between transmissibility and immune status (JID) Enhanced placental antibody transfer efficiency with longer interval between maternal RSV vaccination and birth (AJOG: American Journal of Obstetrics and Gynecology) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Perceptions and Barriers to Outpatient Antiviral Therapy for COVID-19 and Influenza as Observed by Infectious Disease Specialists (OFID) Drug–Drug Interactions with Nirmatrelvir/Ritonavir(Infectious Diseases and Therapy) Drug interaction checker (University of Liverpool) Real-world effectiveness of nirmatrelvir-ritonavir and molnupiravir  (CMI: Clinical Microbiology and Infection) Alleviation of COVID-19 Symptoms and Reduction in Healthcare Utilization Among High-Risk Patients Treated With Nirmatrelvir/Ritonavir (CID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long-COVID Clinical Trials (RECOVER) Initiating Long Covid RECOVERy (Science Translational Medicine) Beyond acute SARS-CoV-2 infection in children (Science Translational Medicine) Long COVID and Osler's Web: Chronic Fatigue Syndrome (goodreads) Sex differences in post infection sequalae  (Science Translational Medicine) Symptoms after Lyme disease: What's past is prologue (Science Translational Medicine) Animal models of Long COVID (Science Translational Medicine) Therapies for Long COVID (Science Translational Medicine) Sex differences and immune correlates of Long Covid development, symptom persistence, and resolution (Science Translational Medicine) The Long COVID ISSUE (Science Translational Medicine) Letters read on TWiV 1168 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin discusses expanded use of the RSV vaccine by GSK, how the youngest member of the MicrobeTV family was hospitalized with RSV, why we are seeing more RSV infections than before the pandemic and how administration of monoclonal antibody therapy does not prevent infection but disease, before reviewing the weekly US COVID update, how SARS-CoV-2 affects neurodevelopment of the fetus and probability of preeclampsia, if giving Paxlovid prevents long COVID, and FDA recommends switching from the XBB.1.5 variant to JN.1 for fall COVID-19 vaccine formulations. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Young “Immune” co-host with RSV (YouTube) RSV on Immune (MicrobeTV) More children hospitalized with RSV after pandemic than before (Pediatrics) France supports Nirsevimab for RSV (Influenza and other respiratory viruses) Protects against disease not infection Nirsevimab (CIDRAP) TWiV tells it likes it is: protects against disease NOT infection (TWiV 695) RSV vaccine access expanded 50-59 (CIDRAP) GSK RSV vaccine expanded use for high risk 50-year olds (GSK) COVID-19 deaths COVID-19 national trend Neurodevelopmental delay in children whose mothers exposed to SARS-CoV-2 (Scientific Reports) Preeclampsia associated with SARS-CoV-2 infection (Journal of Maternal-Fetal & Neonatal Medicine) Effectiveness of nirmatelvir/ritonavir in children and adolescents (Nat Comm) JN.1 for fall COVID-19 boosters (FDA) COVID-19 vaccine booster switch (CIDRAP) EUA for pemgarda (FDA) Infusion centers near you! (pemgarda.com) CDC quarantine guidelines (CDC) Early phase of SARS-CoV-2 infection (COVID.gov) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (IDSociety) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficiacy (JMV) Convalescent plasma recommendations for immunocompromised (ID Society) Updated respiratory virus guidelines (CDC) What to do when your healthcare provider is infected with SARS-CoV-2 (CDC) Managing healthcare staff shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Long COVID evidence based review TWiV shout out (TWiV 1088) Nirmatrelvir-ritonavir prevents long COVID-19? (JAMA Medicine) Contribute to our Floating Doctors fundraiser Letters read on TWiV 1122 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, before discussing viral transmission to adults in healthcare setting, the recently EUA approved protein based COBREVAX vaccine, reviews quarantine guidelines, the use of simnotrelivr for mild to moderate COVID-19, how viral RNA may persist in your cell culture dish following antiviral therapy, continues to dispel the myth of viral rebound, how to pay for Paxlovid, , when to use steroids and the benefits of convalescent plasma, how Paxlovid may prevent long COVID and how complement dysfunction may lead to thromboinflammation during long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Articles and graphs cited in TWIV CU 1080 Respiratory  disease surveillance (CDC) RSV surveillance  (CDC) RSV national trend (CDC) Influenza/flu surveillance  (CDC) Influenza/flu map (CDC) COVID-19  hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Variant hospital admissions (CDC) Transmission in healthcare setting (CID) COBREVAX EUA (Texas Children's Hospital) Quarantine/isolation guidelines (CDC) Simnotrelvir for mild to moderate disease in adults (NEJM) Are your tissue culture cells persistently infected following antiviral therapy (bioRxiv) Structural biology of antivirals for SARS-CoV-2 (Signal Tranduction and Targeted Therapy) To rebound or to not rebound (MMWR) Know your COVID-19 tools (ESMED) How to pay for Paxlovid (PAXCESS) Remdesivir for immunocompromised during variant waves (CID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Patients, experts, Congress…..long COVID oh my! (CIDRAP) Does paxlovid prevent long COVID? (CIDRAP) Persistent complement with thromboinflammation in long COVID (Science) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1082 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin reviews most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US before discussing vaccine effectiveness in children and adolescents, how the pandemic impacted the socioemotional development of infants and toddlers, continues to dispel the myth of viral rebound, how to pay for Paxlovid, reviews quarantine guidelines, when to use steroids and the benefits of convalescent plasma, examines the role of immune aberrations in long COVID and how vaccination may protect against developing long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Respiratory  disease surveillance (CDC) RSV surveillance  (CDC) RSV national trend (CDC) Influenza/flu surveillance  (CDC) Influenza/flu map (CDC) COVID-19  hospital admissions (CDC) COVID-19 national trend(CDC) COVID-19 wastewater testing (biobot) Variant tracker (CDC) Remember when COVID was bad? (Wired) Children and adolescents hospitalized with SARI (Pediatrics) COVID-19 vaccines are effective for adolescents (Pediatrics) Vaccine effectiveness against long COVID in children (Pediatrics) Infant and toddler socioemotional development in the pandemic (JAMA) Quarantine/isolation guidelines (CDC) Should I take Paxlovid? (NY Times) What is this about Paxlovid rebound? (CDC) Rebound is NOT the early inflammatory phase (ESMED) How to pay for Paxlovid (PAXCESS) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (IDSociety) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) T cell dysregulation inflammation and uncoordinated adaptive immune response, Long COVID oh my (Nat Imm) Vaccine effectiveness against long COVID (CIDRAP) Prevention of long COVID by vaccines (Antimicrobial-stewardship and healthcare) Sex and gender relationship with long COVID (Eurosurveillance) Are all vaccines equal in preventing Long COVID? (Lancet) Vaccine naïve individuals, Long COVID and vaccination (medRxiv) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1080 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin reviews recent measles outbreaks, prequalification of nOPV2 by the WHO and most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US before discussing COVID-19 deaths linked to SNPs in C-reactive protein, spread of recent viral variants, how early vaccination reduced hospitalization of those infected with XBB.1.5, reviewed quarantine guidelines, how oral antivirals reduce hospitalizations, dissociation of antiviral treatment from infection rebound, and long COVID, deaths due to administration of hydroxychloroquine, muscle abnormalities and extreme fatigue in individuals with long COVID-19 and how the economics of where you live make long COVID-19 more severe. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode A national measles campaign (CDC) A nation of measles (CDC) The measles unvaccinated in NY (CNN) Philadelphia's measles story (Phila gov) January's measles outbreak (CNN) Prequalify of nOPV2 by WHO (GPEI) Did you prequalify for the novel poliovirus vaccine (CIDRAP) Respiratory  disease surveillance (CDC) RSV surveillance  (CDC) RSV national trend (CDC) Influenza/flu surveillance  (CDC) Influenza/flu map (CDC) COVID-19  hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) Death rate and C-reactive protein SNPs and COVID-19 (Scientific Reports) Variant tracker (CDC) Tracking variant hospitalizations (CDC) Early vaccination against XBB.1.5 hospitalization (Eurosurveillance) Vaccination dashboard (Netherlands) Quarantine/isolation guidelines (CDC) Antiviral gap among the non-hospitalized high risk adults (CID) Oral antivirals prevent hospitalization (medRxiv) Rebound with and without oral antivirals (MMWR) Randomized rebound trials (MMWR) Know your COVID-19 tools (ESMED) The PASC-paxlovid relationship (JAMA) Molnupiravir safety and efficacy (JMV) Convalescent plasma remmendation for immunocompromised (IDSociety) Fluvoxamine for COVID-19 outpatient (RMV) Death by hydroxychloroquine (Biomedicine & Pharmacotherapy) Steroids, dexamethasone at the right time (OFID) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1078 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin discusses the outcomes of SARS-CoV-2, influenza and respiratory syncytial virus infection in pediatric communities under the age of 18 years, the treatment of infants with the human monoclonal anti-respiratory syncytial virus antibody to prevent hospitalizations, most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US, how the SARS-CoV-2/COVID-19 pandemic affected school attendance and child healthcare, how exposure length influenced transmission of SARS-CoV-2, how the durability of the anti-SARS-CoV-2 antibody response to protect against virus re-infection, if administration of oral antiviral therapy affected viral rebound in either the unvaccinated or vaccinated populations, as well as a reminder of the ineffectiveness of antibiotics for treating COVID-19 and the effect of vaccination on post-COVID conditions in children between 5-17 years old. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Pediatric outcomes SARS-CoV-2, flu, RSV (JAMA Peds.) SARS-CoV-2 vs Flu  (Wired) Anti-RSV antibody treatment for infants (NEJM) Respiratory  disease surveillance (CDC) RSV surveillance  (CDC) RSV national trend (CDC) Influenza/flu surveillance  (CDC) COVID-19  hospital admissions (CDC) COVID-19 national trend (CDC) COVID-19 wastewater testing (biobot) COVID-19 school attendance (JPEIDS) COVID-19 pandemic effects children health care (JPEIDS) Digitally measuring transmission (Nat) Antibody titers and re-infection (CMI) Oral antiviral and SARS-CoV-2 rebound (MMWR) Rebound after antiviral controlled trial (MMWR) Vaccination and antiviral therapy (OFID) Antivirals and hospitalization (JMV) Antivirals molnupiravir (JMV) Convalescent plasma and the immunocompromised guidelines (IDSOciety) Steroid and the cytokine storm (OFID) Anticoagulation guidelines (hematology.org) Unnecessary antibiotics (NEJM) Vaccination and long COVID (OFID) RSV vaccination (MMWR) Antivirals and chronic kidney disease (CID) Early administraton of molnupiravir versus ritonavir-boosted nirmatrelvir (Lancet) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1074 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update Dr. Griffin discusses the annual economic burden of respiratory syncytial virus in adults in the US, recombinant or standard-dose influenza vaccine in adults under 65 years of age, maternal vaccine effectiveness against influenza-associated hospitalizations and emergency department visits in iInfants, influenza positive tests reported to CDC by US clinical laboratories, update on COVID-19, risk of severe maternal morbidity associated with SARS-CoV-2 infection during pregnancy, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, optimal timing of nirmatrelvir/ritonavir treatment after COVID-19 symptom onset or diagnosis: target trial emulation, long-term outcomes following hospital admission for COVID-19 versus seasonal influenza: a cohort study, and risk of arrhythmias following COVID-19: nationwide self-controlled case series and matched cohort study. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode RSV economic burden, US (J Inf Dis) Recombinant or standard dose influenza vaccine (NEJM) Maternal vaccine effectiveness against influenza in Infants (JAMA Ped) Weekly influenza surveillance report (MMWR) COVID data tracker (hospital admissions, national trend) Risk of severe maternal morbidity associated with SARS-CoV-2 infection (J Inf Dis) COVID-19 rapid antigen tests with nasal and throat swab specimens (JAMA Net Open) Optimal timing of nirmatrelvir/ritonavir (Nat Comm) Long-term outcomes following hospital admission for COVID-19 vs influenza (Lancet) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1072 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin discusses monkeypox and chickenpox co-infection in southern Nigeria, vaccine effectiveness against influenza A, SARS-CoV-2 neutralizing antibody titers in maternal blood, umbilical cord blood, and breast milk, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, four methods for monitoring SARS-CoV-2 and Influenza A virus activity in schools, efficacy and safety of Baricitinib for the treatment of hospitalized adults with COVID-19, a synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong, consistent absence of cerebrospinal fluid biomarker abnormalities in patients with neurocognitive post-COVID complications, and risk of new-onset long COVID following reinfection with SARS-CoV-2. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Monkeypox and chickenpox co-infection in southern Nigeria (JID) Vaccine effectiveness against influenza A (CID) SARS-CoV-2 neutralizing antibody titers in maternal blood, umbilical cord blood, and breast milk (JOP) COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens (JAMA) Four methods for monitoring SARS-CoV-2 and influenza A virus activity in schools (JAMA) Efficacy and safety of Baricitinib for the treatment of hospitalized adults with COVID-19 (EJMR) A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (The Lancet) Consistent absence of cerebrospinal fluid biomarker abnormalities in patients with neurocognitive post-COVID complications (JID) Risk of new-onset long COVID following reinfection with SARS-CoV-2 (OFID) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin discusses a microbiologist who was harassed during COVID pandemic sues university, use of inactivated poliovirus vaccine for poliovirus outbreak response, safety and immunogenicity of bivalent rsvpref vaccine coadministered with seasonal inactivated influenza vaccine in older adults, coffee as a dietary strategy to prevent SARS-CoV-2 infection, enrollment of pediatric patients in COVID-19 interventional trials, vaccination, immunity, and the changing impact of COVID-19 on infant health, COVID-19 vaccine effectiveness against post- COVID -19 condition among 589722 individuals in Sweden, repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting, protection conferred by COVID-19 vaccination, prior SARS-CoV-2 infection, or hybrid immunity against Omicron-associated severe outcomes among community-dwelling adults, the Novavax heterologous COVID booster demonstrates lower reactogenicity than mRNA vaccines, T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-19, oral VV116 versus placebo in patients with mild-to-moderate COVID-19 in China, and how COVID-19 convalescent plasma therapy decreases inflammatory cytokines, therapeutic heparin in non-ICU patients hospitalized for COVID-19 in the ACTIV-4a trial. Click arrow to play Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Microbiologist who was harassed during COVID pandemic sues university (Nature) Use of inactivated poliovirus vaccine for outbreak response (The Lancet) Safety and immunogenicity of bivalent RSVpreF vaccine coadministered with Influenza vaccine (CID) Coffee as a dietary strategy to prevent SARS-CoV-2 infection (BMC) Enrollment of pediatric patients in COVID-19 interventional trials (JAMA) Vaccination, immunity, and the changing impact of COVID-19 on infant health (PNAS) COVID-19 vaccine effectiveness against post- COVID -19 condition (BMJ) Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting (Nature) Protection conferred by COVID-19 vaccination, prior SARS-CoV-2 infection, or hybrid immunity against Omicron-associated severe outcomes (CID) Novavax heterologous COVID booster demonstrates lower reactogenicity than mRNA (JID) T-cell responses to SARS-CoV-2 infection and vaccination reduce risk of severe COVID-19 (STM) Oral VV116 vs placebo in patients with mild-to-moderate COVID-19 in China (The Lancet) COVID-19 convalescent plasma therapy decreases inflammatory cytokines (MS) Therapeutic heparin in non-ICU patients hospitalized for COVID-19 in the ACTIV-4a trial (Chest) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV on TWiV 1066 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin discusses progress toward measles elimination, risk of severe coronavirus disease 2019 despite vaccination in patients requiring treatment with immune-suppressive drugs, symptoms, viral loads, and rebound among COVID-19 outpatients treated with nirmatrelvir/ritonavir compared to propensity score matched untreated individuals, late administration and corticosteroid usage explain inefficacy in COVID-19 convalescent plasma trial, higher-dose fluvoxamine and time to sustained recovery in outpatients with COVID-19, recombinant C1 inhibitor in the prevention of severe COVID-19, and Epstein-Barr virus reactivation is not causative for post-COVID-19-syndrome in individuals with asymptomatic or mild SARS-CoV-2 disease course. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Progress toward measles elimination (CDC) Risk of severe COVID-19 despite vaccination in patients using immune-suppressive drugs (TID) Symptoms, viral loads, and rebound among COVID-19 outpatients treated with nirmatrelvir/ritonavir compared to untreated individuals (CID) Late administration and corticosteroid usage explain inefficacy in COVID-19 convalescent plasma trial (JID) Higher-dose fluvoxamine and time to sustained recovery in outpatients with COVID-19 (JAMA) Recombinant C1 inhibitor in the prevention of severe COVID-19 (FII) Epstein-Barr virus reactivation is not causative for post-COVID-19-syndrome in individuals with SARS-CoV-2 disease course (BMC) Contribute to our MicrobeTV fundraiser at PWB 37:55 Letters read on TWiV on TWiV 1062 38:16 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin discusses coverage with selected vaccines and exemption from school vaccine requirements among children in kindergarten, seasonality of endemic COVID-19, mRNA SARS-CoV-2 vaccination before vs during pregnancy and omicron infection among infants, extracting symptoms from free-text responses using ChatGPT among COVID-19 cases in Hong Kong, SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy, optimization of antiviral therapy in immunocompromised COVID-19 patients, a study to learn about the study medicines (nirmatrelvir plus ritonavir) in people aged 12 years or older with COVID-19 and a compromised immune system, evaluation of the safety profile and therapeutic efficacy of Remdesivir in children with SARS-CoV-2 infection, effect of neutralizing monoclonal antibody treatment on early trajectories of virologic and immunologic biomarkers in patients hospitalized with COVID-19, and SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Coverage with selected vaccines and exemption from school vaccine requirements among (CDC) Seasonality of endemic COVID-19 (Virology) mRNA SARS-CoV-2 vaccination before vs during pregnancy and Omicron infection among infants (JAMA) Extracting symptoms from responses using ChatGPT among COVID-19 cases (CMI) SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy (AIM) Optimization of antiviral therapy in immunocompromised COVID-19 patients (ClinicalTrials) A study to learn about nirmatrelvir/ritonavir in people with COVID-19 and a compromised immune system (ClinicalTrials) Evaluation of the safety profile and therapeutic efficacy of remdesivir in children with SARS-CoV-2 infection (EJP) Effect of neutralizing monoclonal antibody treatment on virologic and immunologic biomarkers in patients with COVID-19 (JID) SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy (AIM) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV on TWiV 1062 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin discusses stress in America 2023, CDC expanding testing of international air traveler samples to include flu, RSV, and other respiratory viruses, missed opportunities for preventing congenital syphilis, intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and omicron BA.2 variant in Hong Kong, T-cell immunity against severe acute respiratory syndrome coronavirus 2 measured by an interferon-γ release assay is strongly associated with patient outcomes in vaccinated persons hospitalized with delta or omicron variants, masks during pandemics caused by respiratory pathogens, behavioral factors and SARS-CoV-2 transmission heterogeneity within a household cohort in Costa Rica, convalescent plasma for Covid-19–induced ARDS in mechanically ventilated patients, and olfactory and gustatory function 3 years after mild COVID-19. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Stress in America 2023 (APA) CDC expands testing of international air traveler samples to include flu RSV, and other respiratory viruses (CDC) Missed opportunities for preventing congenital syphilis (CDC) Intrinsic and effective severity of COVID-19 case infected with BA.2 variant (JID) Masks during pandemics caused by respiratory pathogens (JAMA) Behavioral factors and SARS-CoV-2 transmission within a household cohort (Nature) Convalescent plasma for Covid-19–induced ARDS in mechanically ventilated patients (NEJM) Olfactory and gustatory function 3 years after mild COVID-19 (JAMA) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV on TWiV 1060 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update, Dr. Griffin discusses health worker–perceived working conditions and symptoms of poor mental health, Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination, newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy, duration of SARS-CoV-2 culturable virus shedding in children, prescribing outcomes in outpatients treated with nirmatrelvir–ritonavir for COVID-19 in an interdisciplinary community clinic, Nirmatrelvir and molnupiravir and post-COVID-19 condition in older patients, optimal duration of systemic corticosteroids in COVID-19 treatment, association between Guillain-Barré syndrome and COVID-19 infection and vaccination, SARS-CoV-2 infection correlates with male benign prostatic hyperplasia deterioration, Transplanting candidates with COVID-19, and favorable experience of transplant strategy including liver grafts from COVID-19 donors. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Routine vaccination coverage (CDC) Outbreak of invasive Group A Streptococcus in children (PIDS) Nirmatrelvir/ritonavir use in pregnant women with SARS-CoV-2 (Nature) Outcomes of SARS-CoV-2 omicron variant infections compared with seasonal influenza and RSV infections in adults (CID) Remdesivir is associated with reduced mortality in COVID-19 patients requiring oxygen (OFID) Effectiveness of nirmatrelvir/ritonavir against the development of Post–COVID-19 conditions among U.S. veterans (AIM) Contribute to our MicrobeTV fundraiser at PWB Letters read on TWiV 1058 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In the first episode of Matters Microbial, Mark introduces himself and his history, talks a bit about his goals for this podcast, then asks three important questions about microbiology and microbiologists with his first guest, Vincent Racaniello. Host: Mark O. Martin Guest: Vincent Racaniello Become a patron of Matters Microbial! Links for this episode MicrobeTV Discord Server Virology blog MicrobeTV on YouTube Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

The entire TWiV team gathers at a theatre in New York City to celebrate a milestone in science podcasting, to reminisce how they joined the show, and to play a game of TWiV Jeopardy. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, Daniel Griffin, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TWiV #1: West Nile virus TWiV #100: TWiV catches a big fish TWiV #200: Threading the NEIDL TWiV #300: So happy together TWiV #400: Harold ‘400' Varmus, a scientist for all seasons TWiV #500: Keep virology weird Randal Despommier Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

In his weekly clinical update Dr. Griffin discusses co-detections of other respiratory viruses among children hospitalized with COVID-19, preprint review should form part of PhD programs and postdoc training, early and increased Influenza activity among children, COVID-19 vaccines versus pediatric hospitalization, SARS-CoV-2 variant-related abnormalities detected by prenatal MRI, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the Omicron variant and severe disease, protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the omicron variant and severe disease, persistent COVID-19 Symptoms at 6 months after onset and the role of vaccination before or after SARS-COV-2 infection, effect of Dexamethasone use on viral clearance among patients with COVID-19, and the impact of vaccination on post-acute sequelae of SARS CoV-2 infection in patients with rheumatic diseases. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Codetections of other respiratory viruses among children with COVID-19 (Pediatrics)  Preprint review should form part of PhD programmes and postdoc training (Nature) Early and increased Influenza activity among children (CDC) COVID-19 vaccines versus pediatric hospitalization (Cell)  SARS-CoV-2 variant abnormalities detected by prenatal MRI (The Lancet)  Protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity (The Lancet)  Persistent COVID-19 symptoms at 6 months and role of vaccination (JAMA) Effects of Dexamethasone use among patients with COVID-19 (IJID) Impact of vaccination on sequelae of SARS CoV-2 in patients with rheumatic diseases (BMJ) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's treatment guide (pdf) Letters read on TWiV 978 Don't crush Paxlovid (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update Dr. Griffin discusses China reporting almost 60,000 Covid-related deaths after abrupt shift in policy, detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination, effect of Fluvoxamine vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19, hyperimmune globulin for severely immunocompromised patients hospitalized with COVID-19, long COVID outcomes at one year after mild SARS-CoV-2 infection, long COVID: major findings, mechanisms and recommendations, a systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19 syndrome and registered on World Health Organization international clinical trials platform, and the effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode China records almost 60,000 COVID-related deaths (SCMP) Detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool (Nature) Effect of Fluvoxamine vs placebo in outpatients with COVID-19 (JAMA) Hyperimmune Globulin for immunocompromised patients with COVID-19 (JID) Long COVID outcomes at one year after mild infection (BMJ)  Major findings, mechanisms and recommendations for Long COVID (Nature) Review of trials investigating therapeutic modalities for post-acute COVID-19 (CMI) Effect of using a structured pacing protocol (JMV) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's treatment guide (pdf) Letters read on TWiV 976 Don't crush Paxlovid (pdf) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update Dr. Griffin discusses poliovirus returns to New York wastewater, COVID-19 is more widespread in animals than we thought, increasing ventilation reduces SARS-CoV-2 airborne transmission in schools, the use of carbon dioxide monitoring to assess ventilation at a national infectious diseases conference, effectiveness of the bivalent mRNA vaccine in preventing severe COVID-19 outcomes, 7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection, and long COVID outcomes at one year after mild SARS-CoV-2 infection. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID-19 more widespread in animals than thought (Nat Geo) Increasing ventilation reduces airborne transmission in schools (Frontiers) Carbon dioxide monitoring to assess ventilation at a NID conference (CID) Paxlovid patient eligbiliity screening checklist (FDA) Effectiveness of bivalent mRNA vaccine in preventing severe COVID-19 (Lancet) Duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection (Lancet) Long COVID outcomes at one year after mild SARS-CoV-2 infection (BMJ) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's treatment guide (pdf) Letters read on TWiV 974 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update Dr. Griffin discusses the infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave, virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants, antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants, comparative effectiveness of third doses of mRNA-based COVID-19 vaccines in US veterans, time to negative PCR conversion among high-risk patients with mild-to-moderate Omicron BA.1 and BA.2 COVID-19 treated by Sotrovimab or Nirmatrelvir, COVID drug Paxlovid was hailed as a game-changer, what happened?, the Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice, SARS-CoV-2 infection and persistence in the human body and brain at autopsy, long-term cardiovascular outcomes of COVID-19, and how heart-disease risk soars after COVID — even with a mild case. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Infectiousness of breakthrough infections & reinfections during Omicron wave (Nature) Virological characteristics of the SARS-CoV-2 XBB variant (bioRxiv) Antibody evasion properties of BQ and XBB subvariants (Cell) Comparative effectiveness of third doses of mRNA vaccines in US veterans (Nature) Time to negative PCR conversion among high-risk patients treated by Sotrovimab or Nirmatrelvir (CMI) Paxlovid patient eligbiliity screening checklist (FDA) COVID drug Paxlovid was hailed as a game-changer. What happened? (Nature) Fc-effector function of COVID-19 convalescent plasma contributes to treatment efficacy (Cell) SARS-CoV-2 infection and persistence in the human body and brain at autopsy (Nature) Long-term cardiovascular outcomes of COVID-19 (Nature) Heart-disease risk soars after COVID (Nature) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's treatment guide (pdf) Letters read on TWiV 972 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update Dr. Griffin discusses Dr. Griffin discusses progress toward poliomyelitis eradication in Afghanistan, reduced risk for Mpox after receipt of 1 or 2 doses of JYNNEOS vaccine compared with risk among unvaccinated persons, reduced airborne transmission of SARS-CoV-2 BA.1 Omicron virus in Syrian hamsters, authorized updated (Bivalent) COVID-19 vaccines for children down to 6 months of age, low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine or a BA.5-bivalent booster, efficacy of antiviral agents against omicron subvariants BQ.1.1 and XBB, incidence of viral rebound after treatment with Nirmatrelvir-Ritonavir and Molnupiravir, and the effectiveness of coronavirus disease 2019 (COVID-19) vaccine in the prevention of post–COVID-19 conditions. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Progress toward Poliomyelitis eradication in Afghanistan (CDC) Reduced risk for Mpox after receipt of 1 or 2 Doses of JYNNEOS vaccine (CDC) Reduced airborne transmission of BA.1 Omicron virus in Syrian hamsters (PLOS) Authorized bivalent vaccines for children down to 6 months of age (FDA) Low neutralization of BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine (Nature) Efficacy of antiviral agents against Omicron subvariants BQ.1.1 and XBB (NEJM) Viral rebound after treatment with Nirmatrelvir-Ritonavir and Molnupiravir (JAMA) Paxlovid patient eligbiliity screening checklist (FDA) Effectiveness of COVID-19 vaccines in prevention of post–infection conditions (ASHE) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's treatment guide (pdf) Letters read on TWiV 964 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update Dr. Griffin discusses Mpox (formerly monkeypox) in women: epidemiological features and clinical characteristics of mpox cases in Spain, April to November 2022, triage of patients with Ebola virus disease, SARS-CoV-2 serology and self-reported infection among adults, serological markers of SARS-CoV-2 infection; anti-nucleocapsid antibody positivity may not be the ideal marker of natural infection in vaccinated individuals, sensitivity of anti-SARS-CoV-2 nucleocapsid protein antibody for breakthrough infections during the epidemic of the Omicron variants, effect of wearing glasses on risk of infection with SARS-CoV-2 in the community, and data-driven identification of post-acute SARS-CoV-2 infection subphenotypes. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Mpox in women: Epidemiological features and clinical characteristics of cases (Eurosurveillance)  Triage of patients with Ebola virus disease (The Lancet)  SARS-CoV-2 serology and self-reported infection among adults (CDC) Serological markers of SARS-CoV-2 infection (JID)  Sensitivity of anti-SARS-CoV-2 nucleocapsid protein antibody (Journal of infection) Effect of wearing glasses on risk of infection with SARS-CoV-2 in the community (JAMA) Paxlovid patient eligbiliity screening checklist (FDA) Data-driven identification of post-acute SARS-CoV-2 infection subphenotypes (Nature) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's treatment guide (pdf) Letters read on TWiV 961 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update Dr. Griffin discusses effectiveness of influenza vaccination of pregnant women for prevention of maternal and early infant Influenza-associated hospitalizations in South Africa, a multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes, single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic induce durable B cell memory responses comparable to replicating smallpox vaccines, whether the risk of still and preterm birth is affected by the timing of symptomatic SARS-CoV-2 infection during pregnancy, medical masks versus N95 respirators for preventing COVID-19 among health care workers, alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants, real-world evidence of novel treatments for COVID-19 on mortality: a nationwide comparative cohort study of hospitalized patients in the 1st, 2nd, 3rdand 4th wave in the Netherlands, and effectiveness and safety of extended thromboprophylaxis in post-discharge patients with COVID-19. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Effectiveness of Influenza vaccination in pregnant women (OFID) Multivalent nucleoside-modified mRNA vaccine against Influenza subtypes (Science) Single and 2-dose vaccinations with modified vaccinia Ankara-Bavarian Nordic (JID) Is the risk of still and preterm birth affected by the timing of symptomatic SARS-CoV-2 infection? (AJOG) Medical masks versus N95 respirators for preventing COVID-19 among health care workers (ACP) Bebtelovimab fact sheet for providers (FDA) Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants (bioRxiV) Paxlovid patient eligbiliity screening checklist (FDA) Real-world evidence of novel treatments for COVID-19 on mortality (OFID) Effectiveness and safety of extended thromboprophylaxis in post-discharge patients with COVID-19 (Thrombosis Research) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's treatment guide (pdf) Letters read on TWiV 959 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

In his weekly clinical update Dr. Griffin discusses Influenza incidence and vaccine effectiveness during the southern hemisphere influenza season in Chile, Nirsevimab for prevention of RSV infection in healthy late-preterm and term infants, severe Monkeypox in hospitalized patients, reinfections with different SARS-CoV-2 Omicron subvariants, impact of community masking on COVID-19 in Bangladesh, unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses, antibody responses to Omicron BA.4/BA.5 bivalent mRNA vaccine booster shot, immunogenicity of bivalent mRNA vaccine boosters, long-term gastrointestinal sequelae following COVID-19, evaluation of an automated text message–based program to reduce use of acute health care resources after hospital discharge, and how in adults with COVID-19, melatonin was assessed for effects on inflammatory markers, clinical signs and symptoms, and mortality. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Influenza incidence and vaccine effectiveness (CDC) Nirsevimab for prevention of RSV (NEJM) Severe Monkeypox in hospitalized patients (CDC) Reinfections with different SARS-CoV-2 Omicron subvariants (CDC) Impact of community masking on COVID-19 (Science) Vaccine elicits protective immunity against sarbecoviruses (Science) Antibody responses to bivalent mRNA vaccine booster shot (Biorxiv) Immunogenicity of bivalent mRNA vaccine boosters (Biorxiv) Long-term gastrointestinal sequelae following COVID-19 (CGH) Remdesivir fact sheet for providers (Veklury)  Bebtelovimab fact sheet for providers (FDA) Evaluation of an automated text message–based program (JAMA) Melatonin assessed for effects on inflammatory markers in COVID patients (Heliyon) PAXLOVID patient eligibility screening checklist (FDA) Contribute to our MicrobeTV fundraiser at PWB Dr. Griffin's treatment guide (pdf) Letters read on TWiV 951 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv

The TWiP team solves the case of the Woman From Hawaii With Allodynia and abdominal pain, bilateral hip and leg pain, dizziness, and diffuse hyperesthesia. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Use coupon code MicrobeTV when purchasing a spike t-shirt from Vaccinated.us Accidental host (TWiP 207) Hero: Dan Colley Letters read on TWiP 209 Become a patron of TWiP Case Study for TWiP 209 Man in his early 70s with PMH sig for HTN, DM-II, HLD, BPH is admitted to the hospital after coming from Guatemala to visit his son. He feels faint with standing and is noted to have a HR in the 40s and does not feel well when he stands. He is also noted to have diarrhea, but this has been going for an unclear period of time. On EKG he is noted to have a RBBB. PMH  HTN, DM-II, HLD, BPH PSH neg Allergies NKADR Social -no toxic habits reported, reports living in Guatemala City but grew up in the rural areas. Enjoys fruit juice FH-noncontrib Exam: slow heart rate, orthostatic A number of blood and stool tests are collected and he is referred to a tertiary care center for implantation of a cardiac pacemaker. At the tertiary care center the patient is seen by an Infectious Disease Specialist and a number of tests are ordered by the Infectious Disease Consultant but they are canceled by Cardiologist who writes in their note “no concern for an infectious process”. Now one of the tests collected at the first hospital returns with an interesting result that is later confirmed by a second test. Send your case diagnosis, questions and comments to twip@microbe.tv

There are a variety of career paths for a scientist, but those paths might not be immediately clear. What is industry? What are some benefits and consequences to a career in industry? Let’s learn to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.

The sheer reduction of poliomyelitis-ridden individuals is a testament to how effective the poliovirus vaccines are. Still, related viruses like rhinoviruses, coxsackieviruses, and enteroviruses cause significant burden to public health. What are picornaviruses? Why is there a need for researching viruses like EV-D68 and EV-A71? Let’s learn to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.  

To be a Nobel Laureate is one of the greatest honors that can be given. What does this prize represent? Where are the Prizes origins? Why are there fewer prizes in economics than other prizes? What are the complications with the Nobel Prize in today’s society? Was Alfred Nobel the last great Alfred? Let’s learn to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.

Why can’t I give birth to an elephant? Why do each of my feet have five toes and not three toes and two conjoined toes? What is DNA and how is it so fundamentally important to how each of us develop? Today, we’ll discuss DNA, the central dogma, and twins. Let’s learn to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.

Some topics are short and sweet, but do not warrant an entire episode of conversation. There have been many requests for smaller topics to be discussed: thusly, establishment of the grab bag is a proper solution. Today we’ll discuss individuals who think they’re more capable than they are; how one determines what reputable information is; coffee without a filter; and, how to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.

Ferns are boring and they look like old houseplants! Well, slow your roll there. Some of these plants' relatives were around before the mega-continent Pangea broke apart. Ferns apply to today’s research. Ferns give you an excuse to use words like fiddlehead, pteridology, and give each of us the chance to become a frond friend. Let’s learn to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.

Squeak! It’s me, a mouse in your domicile. Did you know we mice and humans have an awfully long-standing relationship? Today, we will discuss some important concepts about using mice as model organisms. What’s a mouse? Why would humans use mice as model organisms? What’s the scientific historical basis? Are mice good model organisms? Let’s learn to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.

Many of us have experienced the flu: fever, cough, lethargy, fatigue, vomiting, so on. Likely, less of us have experienced getting the flu shot each year. Whether it be white coat syndrome and a fear of needles, disbelief in vaccinations, or whatever else, only roughly 40% of adults in the United States get the flu shot each year (according to the CDC). In today’s episode, we will discuss influenza and some subtleties of the flu vaccine. What is the flu? What is the vaccine and who designs it? Let’s learn to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.

Three years of Nobel Prizes were directly related to insulin. Today, we’ll discuss what insulin is and why it’s important. Why did the world need a steady supply of insulin? Why did insulin lead to a 1923 Nobel Prize in Medicine or Physiology? How does diabetes play into all of this? Let’s learn to be scientifically conversational. For all references and supplemental information, you can navigate to ascienceshow.com.

On this inaugural episode of Curioscity, we delve into a simple question: do scientists always agree? What is a scientist and what does that person do? Are there any misrepresentations of science or the work done by scientists? Are there examples where scientists disagreed, and it was a good thing?  Let’s learn to be scientifically conversational. Andrew Woodman earned a Ph.D. from The University of Warwick and is currently working as a post-doctoral fellow in Craig Cameron's lab at The Pennsylvania State University. For all references and supplemental information, you can navigate to ascienceshow.com.

The TWiM-opods consider two stories about exosomes, vesicles that are shed from cells: those that eliminate airway pathogens, and those from the plants we eat that shape our gut microbiome. Hosts:  Vincent Racaniello, Michael Schmidt, and Michele Swanson. Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Android, RSS, or by email. Get the entire ASM Podcast Network via our Microbeworld app. Become a patron of TWiM. Links for this episode Exosome swarms eliminate airway pathogens (J Aller Clin Immunol) Exosome release from Bacteria, Eukaryotes, Archaea (Infect Immun) Plant exosomes shape gut microbiome (Cell Host Microbe) Image credit Subscribe to MicrobeTV on YouTube TWiM Listener survey Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

The TWiM team considers the state of the world’s fungi as revealed by a report from the Kew Royal Botanical Gardens, and how Salmonella loses motility to evade host defenses. Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson Take our listener survey. Thanks! asm.org/twimpoll Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a Patron of TWiM! Links for this episode: Subscribe to MicrobeTV on YouTube State of the World’s Fungi 2018 Salmonella loses motility to avoid inflammasome activation (Cell Rep) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv

Hosts: Nels Elde and Vincent Racaniello Nels visits Vincent in the MicrobeTV studio in New York and talks about how key genes of the Homo sapiens innate immune response were acquired from Neanderthals.   Links for this episode Introgressed Neanderthal haplotype at OAS locus (biorXiv) Genetic time travel (Genetics) Genetic history of Ice Age Europe (Nature) Letters read on TWiEVO 8 Science Picks Nels - DNA Clues to our Inner Neanderthal Vincent - Blockhead Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv Become a patron of TWiEVO

The TWiP trifecta solves the case of the Professor Who Went to Brazil, and discuss an amazing case of a tapeworm that turned into a tumor in an AIDS patient. Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin   Links for this episode: Do young doctors need more sleep? (Slate) H. nana tumor in AIDS patient (NEJM) Hymenolepiasis (CDC) H. nana lifecycle (CDC/Wikipedia) Image credit Letters read on TWiP 99 Case study for TWiP 99 This week's case is a 53 yo woman visiting family in US, comes in with intense belly pain, right upper part of belly. Has become strict vegetarian after having breast cancer, on raw vegetable diet (carrots, collect plants in local markets). From Bolivia. Lives in agricultural area, avoids sheep, fearful of dogs. Housekeeper. Married, lives with husband. Noticed pain when came to US. Breast cancer: localized, removed lesion, no therapy, months ago. No allergies, family healthy. No insect bites, lives in concrete house. Physical exam: not febrile, right upper quadrant is very tender, some liver enlargement. CBC: 10,000 white count, mostly eosinophils, liver function: AST, ALT, AlkPhos all normal. Neuro exam: normal. Five months before this diet, she did have normal diet. Some meat, drank milk. Send your diagnosis to twip@twiv.tv Contact Send your questions and comments (email or mp3 file) to twip@twiv.tv Subscribe Subscribe to TWiP (free) in iTunes, by the RSS feed or by email TWiP is a MicrobeTV production