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Peter Huessy. The discussion continues with a focus on films like Fail-Safe and The Day After. Huessy highlights how these movies influenced public perception and presidential policy, including Ronald Reagan's drive for arms reduction. They reflect on the devastating human and economic consequences of a potential nuclear exchange. (16)2945 NAGASAKI
Discover the profound impact of Vitamin K1 on respiratory health in this breakdown of a decade-long study involving over 179,000 adults. While Vitamin K2 often steals the spotlight for bone and heart health, new data suggests K1 is the "ruler of the realm" when it comes to protecting the lungs and reducing the risk of chronic lung disease (COPD).In this episode, we explore the science behind the "Matrix GLA Protein" (MGP), how leafy greens like kale and spinach act as "Green Power" for your lungs' elasticity, and why current daily recommendations for Vitamin K might be falling short of optimal levels.Key Takeaways:The K1 vs. K2 Difference: Why K1 is essential for lung function and fiber elasticity.COPD Risk Reduction: A 16% lower risk found in those with the highest K1 intake.The "Trampoline" Effect: Visualizing how K1 protects the elastic structures that help you breathe.Practical Serving Sizes: How much cooked kale or spinach is needed to reach optimal levels.Timestamps0:00 The Profound Impact of Vitamin K1 vs K2 on Lungs0:36 Analyzing the Study Data: Q1 vs Q5 Intakes 1:13 Is the 70mcg RDI Optimal or Just a Minimum? 1:44 Lung Function and the Difference in Breathing Depth 2:15 The Matrix GLA Protein (MGP): Protecting Lung Elasticity2:30 Green Power: Tracking 179,000 Adults Over a Decade 3:14 16% Reduction in COPD Risk Explained3:55 How K1 Activates Protective Elastic Fibers 4:36 Visual Comparison: Healthy vs. Stiff Lung Function5:01 Detailed Look at Matrix GLA Protein Activation 5:28 Raw vs. Cooked Kale: Maximizing Your K1 Intake 5:56 Study Validation: Hazard Ratios and Confidence Intervals 6:16 K1 for Lungs and Clotting vs. K2 for Bones and Arteries6:56 Addressing the "Healthy Volunteer Effect" in the UK Biobank 7:29 Terminology Glossary and Final Summary 8:10 Are Current RDI Guidelines Too Low for Respiratory Health?#VitaminK1 #COPD #LungHealth #MatrixGlaProtein #STEM #NutritionScience #RespiratoryWellness #HealthyAging #Emphysema #TheCatalystFormal Citation (AMA Style)Li C, Pokharel P, Sim M, et al. Dietary vitamin K intakes, chronic obstructive pulmonary disease, adult asthma, and lung function: a prospective cohort study in the UK Biobank. Am J Clin Nutr. 2026;123(101324):1-12. doi:10.1016/j.ajcnut.2026.101324Medical & Legal DisclaimerDisclaimer: The information provided here is for educational and informational purposes only and is not intended as medical advice. Dietary changes, particularly those involving vitamin K intake, can interact significantly with anticoagulant medications (blood thinners). Always consult with your physician or a qualified healthcare provider regarding a medical condition, diet, or treatment. The narrator and analysis team (The Catalyst) do not monetize this information and provide it as a public service.vitamin K1, K1 VS. COPD, lung blueprint, K1 lung health, COPD prevention, vitamin K-dependent proteins, Matrix Gla Protein, MGP, lung volume, pulmonary function, FEV1, FVC, spirometry, UK Biobank, dietary phylloquinone, green leafy vegetables, lung structure preservation, elastic fiber degradation, emphysema, nutritional epidemiology, chronic respiratory disease, respiratory wellness, Catalyst analysis, Ralph Turchiano, high-energy science, STEM education, non-monetized data.
Paul Booth is a performance nutritionist and exercise physiologist who works with elite ultra-endurance athletes and teams, including the Salomon International team, and was the nutritionist behind both the men's and women's UTMB winners in 2025, Tom Evans and Ruth Croft. We cover the science and practice of fuelling: how many carbs you actually need, why the high-carb trend has run ahead of the evidence, and how to get hydration and electrolytes right for triathlon and ultra-endurance racing. HIGHLIGHTS AND KEY TOPICS: Why Paul calls himself a "90-gram carb guy" and where the carb ceiling actually sits What the science says about 90 versus 120 grams of carbohydrate per hour The physiology of carbohydrate absorption, and how to work out your own intake for an Ironman without lab testing Gut training: building tolerance to carbs and fluid in the weeks before a race A simple DIY method to work out your sweat rate and fluid needs Why hydration, not carbs, is behind most race-day gut problems Electrolytes: what the evidence supports and what is mostly marketing Fuelling through heat, altitude and ageing, plus listener questions on glycogen-depleted training, honey and more SHOWNOTES, LINKS, RESOURCES AND RELATED EPISODES: Follow Paul and Performance Gains Nutrition on his website and Instagram The shownotes for today's episode can be found here. The full podcast episode archives (including category filters) can be found here. Related episodes: Carbohydrates, science and practice with Tim Podlogar, PhD | EP#354 Nutrition and hydration data from Kona and 70.3 Worlds with Andy Blow | EP#365 Aerobic training and testing with Scott Johnston | EP#326 Richard Laidlow | EP#403 Studies discussed: Fuelled or Fooled? Examining the Evidence and Mechanisms Behind Ultra-High Carbohydrate Intake in Endurance Athletes - Plews et al. 2026 Graded Carbohydrate Ingestion up to 120 g/h Attenuates the Reduction in Critical Power Following 3 h of Moderate-Intensity Exercise in a Dose-Dependent Manner - Norte et al. 2026 13C-labelled glucose-fructose show greater exogenous and whole-body CHO oxidation at 120 vs 60 & 90 g/h in elite male marathoners - Ravikanti et al. 2025 Exogenous Glucose Oxidation During Exercise Is Positively Related to Body Size - Ijaz et al. 2024 Fructose-maltodextrin ratio governs exogenous and other CHO oxidation and performance - O'Brien et al. 2013 Nutritional intake and gastrointestinal problems during competitive endurance events - Pfeiffer et al. 2012 Modelling sodium requirements of athletes across exercise scenarios – when to test and target, or season to taste - McCubbin 2022 Could It Bee? Honey Ingestion Induces Comparable Metabolic Responses to a Traditional Carbohydrate Sports Product - Fortis et al. 2025 SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership. ZenAI is the next frontier of podcasting. It lets you turn your ideas into a podcast without any knowledge of audio editing, video, or production. You do the talking, and the AI handles the production, editing, clipping, and the rest, and you can direct your AI producer in plain English. You can even record from your phone, so no expensive studio gear is needed to sound great. ZenAI is a new product from Zencastr, a platform I've been a paying customer of for over nine years here at That Triathlon Show. ZenAI is currently in invite-only beta. Join the waitlist today here.LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we doContact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs)Subscribe to our NewsletterFollow us on InstagramLearn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals.HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released.Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far!Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones).Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
For more on this Donal Moriarty, Chief Corporate Affairs Officer at Aer Lingus and Hazel Nolan, National Secretary of Fórsa.
The Federal government just proposed turning grizzly bear management over to Wyoming, Montana, and Idaho--without delisting. How is this possible? The guys discuss the proposed rule, and some of the history of the past 15 years that led to the proposal (Dave takes WAY too much credit!). Next, they discuss the recent Executive Order that shrinks the boundaries of Bears Ears and Grand Staircase-Escalante National Monuments in southern Utah. They explain a little of the history, the pendulum swings, and why it's time to start thinking about durability, not dogma. Finally, they give a quick update on a rule that changes the definition of "harm" under the Endangered Species Act. Lots of meat in this episode. Want to share ideas, complain, praise, or just engage in a conversation. Reach out at our new email address yourmountainpodcast@gmail.com, or find us on Instagram or Facebook: @itsyourmountain.
4:20 pm: Nic Dunn, Senior Fellow and V.P. of Strategy for the Sutherland Institute, joins the program to discuss his piece about using empowerment accounts as a streamlined system to fight poverty.4:38 pm: Garfield County Commissioner Leland Pollock joins the show for a conversation about President Trump's expected reduction of the Bears Ears and Grand Staircase-Escalante National Monuments.6:20 pm: Peter Laffin, Senior Editor for the Washington Examiner, joins the show to discuss his piece about how President Trump needs to reset the conversation about Iran, beginning with American citizens.
The data shows a total of 4.2 million tonnes of was handled in 2025, down from close to 4.4 million tonnes the year before.
Amy MacIver speaks to Carl Lindemann | Outreach Coordinator, Astronomical Society of Southern Africa (ASSA) Cape Centre; Former Dark Sky Officer about why darkness is good for the environment and the go-to spots in Cape Town to experience true and uninterrupted darkness. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.
University of Minnesota Extension's two-day field School for Ag Professionals is coming up July 29 and July 30, 2026. If you're an agronomist, a retailer, dealer or consultant, if you're a summer field scout - we encourage you to attend these small-group, hands-on sessions led in the field by experienced instructors. 12 Certified Crop Advisor CEUs credits are available! For all the details, including info on lodging, visit z.umn.edu/AgFieldSchool2026Nitrate reduction with perennial plants is the topic on today's Advancing Nitrogen Smart podcast. What are some pros and cons of covers like rye, oat and alfalfa for reducing nitrate? How do they compare in terms of biomass or establishment? What sets alfalfa apart as a cover crop candidate? How does our Minnesota climate affect a strategy for perennials? How could cover crop benefits stack up when used in conjunction with a dairy operation for example? Do some areas of the landscape benefit from perennials more than others? All this and more on the 38th episode of Advancing Nitrogen Smart.Guests:Brad Carlson, Extension educator (Mankato)Dan Kaiser, Extension nutrient management specialist (St. Paul)Additional resources:Cover CropsBest management for cover crops in unfavorable weather patternsGrowing cover crops in Minnesota: 4 great resources to get you startedVideo: Can cover crops reduce nitrate loss in tile drainage?Midwest Cover Crops Council (Minnesota)Strategic Farming: Let's talk cover crops!---For the latest nutrient management information, subscribe to the Nutrient Management Podcast. And don't forget to subscribe to the Minnesota Crop News daily or weekly email newsletter, subscribe to our YouTube channel, like UMN Extension Nutrient Management on Facebook, follow us on X (formerly twitter), and visit our website.If you have questions or comments, please email us at nutmgmt@umn.edu.Advancing Nitrogen Smart is proud to be supported by the farm families of Minnesota and their corn check-off investment through Minnesota Corn.
OA1276 - Who could have predicted this? Us! The Trump administration has made their complete disdain for people with disabilities clear since day one. We've called it out before, and the natural progression of those efforts came to a head mid-June when they announced their intention to turn over governance of special education to RFK Jr in HHS (least trusted man in America when it comes to the needs of your child with a disability), continue dismantling the Department of Education overall, further reduce their investigations of educational discrimination, and, just two days later, their commitment to overturning major protections against forced institutionalization. What's happening, how did we get here, why does it matter, and what can anyone do about it? Tune in to find out. OA episode callbacks: 1238 Deep dive on Olmstead 1180 the history of forced institutionalization and “ugly laws”, and the executive order “Ending crime and disorder on America's streets” 1141 The Section 504 protests 1171 A.J.T. v Osseo area schools (rights to accommodations for students with disabilities) Part 1; attempted dismantling of Olmstead: Olmstead v. L.C. ex rel. Zimring, 527 U.S. 581 (1999) 28 C.F.R. § 35.130(d) Exec. Order No. 14321, 90 Fed. Reg. 35817 (Jul 24, 2025) Application of the Rehabilitation Act and Americans with Disabilities Act to State Institutionalization of Patients with Severe Mental Illness or Disabilities, 50 Op. O.L.C. __ (June 18, 2026) Part 2; the dismantling of the Department of Education: Exec. Order No. 14242, 90 Fed. Reg. 13679 (Mar. 20, 2025) Compl., State of New York v. McMahon, No. 1:25-cv-10601 (D. Mass. amended 01/09/2026) McMahon v. New York, 606 U.S. ___ (2025) Interagency Agreement Between the U.S. Department of Education and U.S. Department of Labor Relating to the Office of Elementary and Secondary Education (OESE) (plus addendums) Christy Wolfe (Dec. 16, 2025), Transferring K-12 Programs to Labor: Why Costs and Logistics Could Be a Problem for States and Schools, Bipartisan Policy Center Jennifer Smith Richards & Jodi S. Cohen (Mar. 2, 2026), ProPublica Sues Education Department for Withholding Records About Discrimination in Schools, ProPublica. U.S. Government Accountability Office (Feb. 2, 2026), Department of Education: Full Costs and Savings Estimate Needed for Reduction-in-Force and Restructuring of the Office for Civil Rights. U.S. Dept. of Education (June 16, 2026). U.S. Department of Education Announces Additional Partnerships to Strengthen Coordination for Individuals with Disabilities Programs, Bolster Civil Rights Enforcement. A.J.T. v. Osseo Area Schools, Independent School Dist. No. 279, 605 U.S. 335 (2025) Section 504 of the Rehabilitation Act of 1973: 29 U.S.C. § 794 Individuals with Disabilities Education Act: 20 U.S.C. § 1400-1409 Check out the OA Linktree for all the places to go and things to do!
Ebook: https://drive.google.com/file/d/1AUsxg05dXkKFeAa64kC0u16XynnSx68o/view?usp=drive_link Episode Description: Every peptide conversation right now is about GLP-1 drugs, BPC-157, and TB-500. Nobody is talking about the one with 50 years of published research that your body is already making and losing as you age. GHK-Cu is a naturally occurring tripeptide that declines by 60% between the ages of 20 and 60. That decline tracks directly with the loss of skin elasticity, slower wound healing, thinning hair, reduced collagen production, and rising inflammation. In randomized controlled trials it has outperformed Rogaine for hair growth, shown a 55% reduction in visible wrinkles, and been documented to positively affect the expression of over 4,000 human genes. Dr. G calls it his favorite peptide, and his partner uses it on her face every day. In this episode, you will learn: • How GHK-Cu works as a copper delivery vehicle at the cellular level, why it modulates gene expression across 31% of the human genome, and what that means for tissue repair, inflammation, and biological aging • The head to head randomized controlled trial where GHK-Cu outperformed minoxidil for hair count, follicle size, and the active growth phase of the hair cycle • Exactly what to look for when buying GHK-Cu cream, why the peptide is chemically fragile, what packaging and pH range to require, and the red flags that tell you to walk away from a product Timestamps: 0:00 - Intro 1:44 - What GHK-CU Actually Is and How It Was First Discovered in 1973 3:10 - Why a 60% Decline in GHK-CU Between Ages 20 and 60 Tracks Directly With Aging 4:40 - What Makes GHK-CU Different From Every Other Popular Peptide 6:00 - How It Stimulates Collagen, Elastin & the Extracellular Matrix 7:15 - The Human Trial Showing a 51% Increase in Collagen Density From Topical Application 8:00 - The 4,000 Genes GHK-CU Affects (And What the Broad Institute Found) 9:30 - Anti-Inflammatory Effects: Why This Matters for Biological Aging 10:30 - Wound Healing, Angiogenesis & Tissue Repair Across Skin, Bone, Gut and Liver 11:30 - The 2022 RCT: 55.7% Reduction in Visible Wrinkles After 12 Weeks 12:30 - Hair Growth: Outperforming Minoxidil in a Head-to-Head Randomized Trial 14:30 - Why the Lower Dose (50mg/ml) Outperformed the Higher Dose 15:30 - Safety Profile, Contraindications & the "Copper Uglies" Explained 17:00 - How to Buy GHK-CU: Concentration, Packaging, pH & What to Avoid Learn more about your ad choices. Visit megaphone.fm/adchoices
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3448: Kylee shares practical strategies that helped her reduce drinking, from surrounding herself with supportive people and sober-curious communities to building a lifestyle filled with meaningful, alcohol-free activities. She also explores how investing in personal flourishing through relationships, purpose, health, and fulfillment can make alcohol far less appealing, offering an encouraging roadmap for anyone looking to change their relationship with drinking. Read along with the original article(s) here: https://www.ablueskymind.com/blog/how-to-cut-back-on-drinking-tips Quotes to ponder: "Everything we can do drunk we can also do sober, and that we don't have fun because of alcohol, we have fun because of what we are doing and who we are with." "Know the difference between things that might not be great for you, and things that take you down and keep you stuck and bring out your worst and get in the way of your best life." "A big part of the journey I'm on now is retraining myself to fully believe that I can have a rich and whole life without “going out” culture." Episode references: Gallup Alcohol Consumption Survey: https://news.gallup.com/poll/467507/percentage-americans-drink-alcohol.aspx Learn more about your ad choices. Visit megaphone.fm/adchoices
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3448: Kylee shares practical strategies that helped her reduce drinking, from surrounding herself with supportive people and sober-curious communities to building a lifestyle filled with meaningful, alcohol-free activities. She also explores how investing in personal flourishing through relationships, purpose, health, and fulfillment can make alcohol far less appealing, offering an encouraging roadmap for anyone looking to change their relationship with drinking. Read along with the original article(s) here: https://www.ablueskymind.com/blog/how-to-cut-back-on-drinking-tips Quotes to ponder: "Everything we can do drunk we can also do sober, and that we don't have fun because of alcohol, we have fun because of what we are doing and who we are with." "Know the difference between things that might not be great for you, and things that take you down and keep you stuck and bring out your worst and get in the way of your best life." "A big part of the journey I'm on now is retraining myself to fully believe that I can have a rich and whole life without “going out” culture." Episode references: Gallup Alcohol Consumption Survey: https://news.gallup.com/poll/467507/percentage-americans-drink-alcohol.aspx Learn more about your ad choices. Visit megaphone.fm/adchoices
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3447: Kylee shares the intentional mindset shifts, tracking strategies, and belief-changing tools that helped her dramatically reduce her alcohol consumption after years of normalizing unhealthy drinking habits. By examining personal assumptions about alcohol, benchmarking drinking patterns, and surrounding herself with supportive people, she offers a practical framework for anyone looking to build a healthier relationship with drinking. Read along with the original article(s) here: https://www.ablueskymind.com/blog/how-to-cut-back-on-drinking-tips Quotes to ponder: "Regretting how much you drank or your decisions around drinking might be “normal” in some social circles, but it is never “healthy.”" "One of my big breakthroughs is that I associate drinking with a “fun” and “rich” life, one that makes me happy, interesting, and likable." "Building awareness is a powerful tool for behavior change, and using a "drink counter" app or practice is a great place to start when it comes to drinking." Episode references: Quit Like a Woman: https://www.amazon.com/Quit-Like-Woman-Radical-Obsession/dp/1984825054 Reframe: https://www.joinreframeapp.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3447: Kylee shares the intentional mindset shifts, tracking strategies, and belief-changing tools that helped her dramatically reduce her alcohol consumption after years of normalizing unhealthy drinking habits. By examining personal assumptions about alcohol, benchmarking drinking patterns, and surrounding herself with supportive people, she offers a practical framework for anyone looking to build a healthier relationship with drinking. Read along with the original article(s) here: https://www.ablueskymind.com/blog/how-to-cut-back-on-drinking-tips Quotes to ponder: "Regretting how much you drank or your decisions around drinking might be “normal” in some social circles, but it is never “healthy.”" "One of my big breakthroughs is that I associate drinking with a “fun” and “rich” life, one that makes me happy, interesting, and likable." "Building awareness is a powerful tool for behavior change, and using a "drink counter" app or practice is a great place to start when it comes to drinking." Episode references: Quit Like a Woman: https://www.amazon.com/Quit-Like-Woman-Radical-Obsession/dp/1984825054 Reframe: https://www.joinreframeapp.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices
“I may be the expert in cancer, but you are the expert in you.”—Elisa Port, MDGround Truths is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.Dr. Elisa Port is Professor of Surgery, Icahn School of Medicine at Mount Sinai; Chief of Breast Surgery for the Mount Sinai Health System; Director of the Dubin Breast Center; and Director of the Center of Excellence for Breast Cancer at the Mount Sinai Tisch Cancer Center, a NCI-Designated Comprehensive Cancer Center. She is remarkably well qualified to provide guidance for prevention and treatment of breast cancer, and runs a model program at Mount Sinai in New York (←we'll get into why I say that).She has just published a terrific book that centers around the concept of informed optimism. Many of her patient stories are integrated.We tried to cover the waterfront during our conversation including:—4 Ws for reduction of risk: weight, walking, wine, and working out (especially in Nature, “green exercise”)—Only 10-12% of women will ever develop breast cancer during their lives —Role of adipocytes (fat cells), aka estrogen and inflammation factories—Misinformation (underlying the need for this book)—Pervasive myths of magic supplements, with safety issues of unregulated intravenous drips and others when analyzed turned out to be crushed up, dried house plants—Total body MRI: mixed results from her patients —Breast cancer on the rise in young women. Dr. Port relates about recent patients diagnosed in their 20s. Some without BRCA or other pathogenic mutation. Why?—Mammograms in non-dense breasts pick up 80-90% of breast cancer. It's the 40-50% women with dense breasts, which the scan is trying to find a polar bear in a snowstorm, is a problem. The problem with false-positives.—Use of AI with mammography for increased initial detection, prevention, detect high-risk in women with a “normal” mammogram, and risk of heart disease (see my recent Ground Truths and piece in The Lancet on this important topic)—Mount Sinai provides Transpara AI (the one validated by the big Sweden trial of >100,000 women) to all women getting mammograms FOR FREE. That is the best validated AI tool in medicine today!—How a mammogram saved a patient's life, not about breast cancer!—Hormone replacement and birth control pills. How to assess benefit and risk in women young and older? Differences in the hormone risks.—Tamoxifen for primary prevention in high-risk people. Reduction of breast cancer in 50% or more in these women. In some subgroups reduction as high as 80%!—GLP-1 drugs may reduce breast cancer risk and this may not just be related to weight loss—Lack of utilization of Genetic testing (it could be your father). I disagreed with respect to use of polygenic risk scores, as I wrote about in SUPER AGERS—“I just wanted to scream out on top of the mountain about genetic testing, family history, and early screening.” Tennis legend Chris Evert—The lack of our ability to assess the immune system in the clinic and how that could change the face of prevention and very early detection of breast cancerAn infographic summary I made on Dr. Port's book with the help of NotebookLM****************************************Thank you YOUR DOCTOR KLOVER, Diane Romero, Bob Fleischman, Danielle, MagnaAnimus, and 450+ others for tuning into my live video with Elisa Port! Join me for my next live video in the app.A big thanks to all the Ground Truths subscribers from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. If you're not a subscriber, please join!If you found this interesting PLEASE share it!Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Let me know topics that you would like to see covered.Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support a record number of 51 summer interns coming in 2026! These are high school, college and medical students selected from thousands of applicants. We couldn't do this expanded program without the funds coming in through Ground Truths. Get full access to Ground Truths at erictopol.substack.com/subscribe
This podcast shows you how to fully recover from OCD.Each episode breaks down the exact techniques and nuances that stop rumination, reduce compulsions, and help you retrain your brain out of the OCD cycle. We cover every major OCD theme, including:Pure-O OCDRelationship OCDHarm OCDReal Event OCDSO-OCD / Sexuality OCDReligious / Scrupulosity OCDCleaning & Contamination OCDPhysical CompulsionsAll other OCD subtypesMy goal is simple: clear guidance that actually works, explained in a way that is calm, direct, and easy to apply immediately.You can fully recover from OCD. Don't give up — you're not stuck, and your brain can change.
The Education Department's Office of the Chief Information Officer lost more than half of its staff in early 2025 during the Trump administration's reduction-in-force campaign, leaving some suboffices completely empty, the agency's Office of the Inspector General found in a report issued Monday. The OIG used Microsoft Office and Teams to track down who was subject to the RIF during the first nearly ten weeks of President Donald Trump's second term, finding it gutted 40% or 1,579 of the agency's workers in total. The OIG said it was presented with a scope limitation for the review due to the department not providing all requested information or giving unfettered access to Department staff, which limited its ability to fully address the review objective. Specifically in the CIO's office, the OIG counted 44 remaining employees of the 92 employed in January 2025 — a 52% reduction. About 8% of all separated employees in the agency were in IT management, it found, and about $6 million in OCIO contracts were terminated as part of the Department of Government Efficiency's massive agency reorganization campaign in early 2025. Suboffices within the OCIO that are statutorily required to oversee all departmental operational enterprise IT infrastructures and software, develop IT investment performance measures and conduct security reviews mandated by the Federal Information Security Modernization Act have no remaining employees, the report said. NASA issued a long-awaited list of awardees for the latest iteration of a multibillion-dollar cross-government IT acquisition vehicle, moving the large-scale contract forward. In a brief notice on Monday, the agency said it would start processing the awards for the sixth generation of its Solutions for Enterprise‑wide Procurement contract, known as SEWP VI. It also disclosed more than 2,100 awardees across three categories: IT solutions, enterprise-wide IT services, and mission-based IT services. Among the hundreds of awardees, the list includes IBM, Leidos, KPMG, Carahsoft Technology Corp., Peraton, REI Systems, Science Applications International Corporation (SAIC), CACI, Cherokee Nation Government Solutions, Amivero and Guidehouse. All of the awards are indefinite-delivery, indefinite-quantity, with a 10-year ordering period and a maximum ordering value of $20 billion. The contract period begins Nov. 1 and will run through October 2036. The Daily Scoop Podcast is available every Monday-Friday afternoon. If you want to hear more of the latest from Washington, subscribe to The Daily Scoop Podcast on Apple Podcasts, Soundcloud, Spotify and YouTube.
WBBM political editor Geoff Buchholz reports on Chicago Mayor Brandon Johnson's new executive order creating a dedicated Office of Gun Violence Reduction.
WBBM political editor Geoff Buchholz reports on Chicago Mayor Brandon Johnson's new executive order creating a dedicated Office of Gun Violence Reduction.
WBBM political editor Geoff Buchholz reports on Chicago Mayor Brandon Johnson's new executive order creating a dedicated Office of Gun Violence Reduction.
PainExam Podcast Show Notes NAD+ Supplementation in Pain and Inflammation: Hype, Hope, or Emerging Science? Hosted by: PainExam Podcast Presented by: NRAP Academy (Neuromodulation, Regional Anesthesia & Pain) Host: David Rosenblum, MD Episode Overview In this episode of the PainExam Podcast, we explore the growing interest in NAD+ (Nicotinamide Adenine Dinucleotide) supplementation and its potential role in pain management, inflammation reduction, cellular recovery, and healthy aging. NAD+ is a naturally occurring coenzyme found in every living cell and is essential for energy production, mitochondrial function, DNA repair, and cellular resilience. As NAD+ levels decline with age, chronic stress, inflammation, and disease, researchers have begun investigating whether restoring NAD+ levels may improve outcomes in chronic pain conditions and inflammatory disorders. We review the current science, discuss potential mechanisms of action, and examine how NAD+ therapy is being integrated into regenerative medicine, wellness programs, and pain management practices. What is NAD+? NAD+ is a coenzyme involved in: ✅ Cellular energy production (ATP generation) ✅ Mitochondrial health ✅ DNA repair pathways ✅ Oxidative stress reduction ✅ Neuroprotection ✅ Cellular signaling ✅ Activation of longevity-associated proteins called sirtuins Without adequate NAD+, cells become less efficient at producing energy and managing inflammation. Why Might NAD+ Matter in Chronic Pain? Many chronic pain conditions involve: Mitochondrial dysfunction Oxidative stress Neuroinflammation Peripheral and central sensitization Impaired cellular recovery Researchers hypothesize that optimizing NAD+ levels may help address several of these pathways simultaneously. Potential areas of interest include: Neuropathic Pain NAD+ may support: Nerve repair Axonal recovery Mitochondrial function within neurons Reduction of oxidative injury Inflammatory Pain NAD+ influences inflammatory signaling pathways and may help modulate: Cytokine production Immune cell activity Cellular stress responses Fatigue and Recovery Patients with chronic pain frequently report: Fatigue Brain fog Reduced exercise tolerance Poor recovery Because NAD+ plays a critical role in energy metabolism, some clinicians report improvements in energy and recovery following supplementation. Potential Mechanisms of Action 1. Improved Mitochondrial Function Mitochondria generate ATP, the body's energy currency. Reduced NAD+ levels are associated with: Cellular aging Impaired energy production Increased inflammation Supplementation may help restore mitochondrial efficiency. 2. Activation of Sirtuins Sirtuins are proteins involved in: Cellular repair Longevity Metabolic regulation Inflammation control NAD+ serves as a critical substrate for sirtuin activity. 3. DNA Repair Support NAD+ is required for enzymes known as PARPs (Poly ADP Ribose Polymerases), which participate in DNA repair processes following cellular injury. 4. Reduction of Oxidative Stress Chronic inflammation often produces excessive reactive oxygen species (ROS). NAD+ may help maintain cellular antioxidant defenses and reduce oxidative injury. Routes of NAD+ Supplementation Intravenous (IV) NAD+ Most commonly marketed in wellness and recovery clinics. Potential advantages: Direct systemic delivery Avoids gastrointestinal absorption issues Allows higher dosing protocols Potential limitations: Cost Time commitment Variable evidence base Oral Precursors Rather than NAD+ itself, many supplements provide precursors such as: Nicotinamide Riboside (NR) Nicotinamide Mononucleotide (NMN) These compounds are converted into NAD+ within the body. What Does the Evidence Show? Current evidence remains preliminary. While preclinical and mechanistic studies are promising, large-scale randomized controlled trials evaluating NAD+ specifically for chronic pain are still limited. Areas under active investigation include: Neuropathic pain Neurodegenerative disorders Chronic fatigue syndromes Recovery optimization Healthy aging Patients should understand that NAD+ therapy remains an emerging treatment rather than a standard evidence-based pain intervention. Safety Considerations Reported side effects may include: Nausea Flushing Chest tightness during rapid infusions Headache Fatigue Lightheadedness Most adverse effects appear infusion-rate dependent and can often be minimized through slower administration protocols. Patients should discuss treatment with a qualified healthcare professional, especially if they have: Cardiovascular disease Active cancer Significant medical comorbidities Clinical Pearls for Pain Physicians ✔ Consider NAD+ as a potential adjunct—not a replacement—for evidence-based pain care. ✔ Continue emphasizing exercise, sleep optimization, nutrition, behavioral health, and appropriate interventional therapies. ✔ Discuss realistic expectations with patients. ✔ Recognize that evidence continues to evolve. ✔ Focus on patient-centered outcomes rather than laboratory markers alone. Key Takeaways NAD+ is essential for cellular energy production and repair. Declining NAD+ levels may contribute to aging, inflammation, and chronic disease. Early evidence suggests possible benefits in inflammation, recovery, fatigue, and nerve health. Robust pain-specific clinical trials remain limited. NAD+ therapy should currently be viewed as an adjunctive and investigational strategy in pain management. Resources for Physicians Pain Medicine Board Preparation Prepare for the ABA Pain Medicine Boards with:
PainExam Podcast Show Notes NAD+ Supplementation in Pain and Inflammation: Hype, Hope, or Emerging Science? Hosted by: PainExam Podcast Presented by: NRAP Academy (Neuromodulation, Regional Anesthesia & Pain) Host: David Rosenblum, MD Episode Overview In this episode of the PainExam Podcast, we explore the growing interest in NAD+ (Nicotinamide Adenine Dinucleotide) supplementation and its potential role in pain management, inflammation reduction, cellular recovery, and healthy aging. NAD+ is a naturally occurring coenzyme found in every living cell and is essential for energy production, mitochondrial function, DNA repair, and cellular resilience. As NAD+ levels decline with age, chronic stress, inflammation, and disease, researchers have begun investigating whether restoring NAD+ levels may improve outcomes in chronic pain conditions and inflammatory disorders. We review the current science, discuss potential mechanisms of action, and examine how NAD+ therapy is being integrated into regenerative medicine, wellness programs, and pain management practices. What is NAD+? NAD+ is a coenzyme involved in: ✅ Cellular energy production (ATP generation) ✅ Mitochondrial health ✅ DNA repair pathways ✅ Oxidative stress reduction ✅ Neuroprotection ✅ Cellular signaling ✅ Activation of longevity-associated proteins called sirtuins Without adequate NAD+, cells become less efficient at producing energy and managing inflammation. Why Might NAD+ Matter in Chronic Pain? Many chronic pain conditions involve: Mitochondrial dysfunction Oxidative stress Neuroinflammation Peripheral and central sensitization Impaired cellular recovery Researchers hypothesize that optimizing NAD+ levels may help address several of these pathways simultaneously. Potential areas of interest include: Neuropathic Pain NAD+ may support: Nerve repair Axonal recovery Mitochondrial function within neurons Reduction of oxidative injury Inflammatory Pain NAD+ influences inflammatory signaling pathways and may help modulate: Cytokine production Immune cell activity Cellular stress responses Fatigue and Recovery Patients with chronic pain frequently report: Fatigue Brain fog Reduced exercise tolerance Poor recovery Because NAD+ plays a critical role in energy metabolism, some clinicians report improvements in energy and recovery following supplementation. Potential Mechanisms of Action 1. Improved Mitochondrial Function Mitochondria generate ATP, the body's energy currency. Reduced NAD+ levels are associated with: Cellular aging Impaired energy production Increased inflammation Supplementation may help restore mitochondrial efficiency. 2. Activation of Sirtuins Sirtuins are proteins involved in: Cellular repair Longevity Metabolic regulation Inflammation control NAD+ serves as a critical substrate for sirtuin activity. 3. DNA Repair Support NAD+ is required for enzymes known as PARPs (Poly ADP Ribose Polymerases), which participate in DNA repair processes following cellular injury. 4. Reduction of Oxidative Stress Chronic inflammation often produces excessive reactive oxygen species (ROS). NAD+ may help maintain cellular antioxidant defenses and reduce oxidative injury. Routes of NAD+ Supplementation Intravenous (IV) NAD+ Most commonly marketed in wellness and recovery clinics. Potential advantages: Direct systemic delivery Avoids gastrointestinal absorption issues Allows higher dosing protocols Potential limitations: Cost Time commitment Variable evidence base Oral Precursors Rather than NAD+ itself, many supplements provide precursors such as: Nicotinamide Riboside (NR) Nicotinamide Mononucleotide (NMN) These compounds are converted into NAD+ within the body. What Does the Evidence Show? Current evidence remains preliminary. While preclinical and mechanistic studies are promising, large-scale randomized controlled trials evaluating NAD+ specifically for chronic pain are still limited. Areas under active investigation include: Neuropathic pain Neurodegenerative disorders Chronic fatigue syndromes Recovery optimization Healthy aging Patients should understand that NAD+ therapy remains an emerging treatment rather than a standard evidence-based pain intervention. Safety Considerations Reported side effects may include: Nausea Flushing Chest tightness during rapid infusions Headache Fatigue Lightheadedness Most adverse effects appear infusion-rate dependent and can often be minimized through slower administration protocols. Patients should discuss treatment with a qualified healthcare professional, especially if they have: Cardiovascular disease Active cancer Significant medical comorbidities Clinical Pearls for Pain Physicians ✔ Consider NAD+ as a potential adjunct—not a replacement—for evidence-based pain care. ✔ Continue emphasizing exercise, sleep optimization, nutrition, behavioral health, and appropriate interventional therapies. ✔ Discuss realistic expectations with patients. ✔ Recognize that evidence continues to evolve. ✔ Focus on patient-centered outcomes rather than laboratory markers alone. Key Takeaways NAD+ is essential for cellular energy production and repair. Declining NAD+ levels may contribute to aging, inflammation, and chronic disease. Early evidence suggests possible benefits in inflammation, recovery, fatigue, and nerve health. Robust pain-specific clinical trials remain limited. NAD+ therapy should currently be viewed as an adjunctive and investigational strategy in pain management. Resources for Physicians Pain Medicine Board Preparation Prepare for the ABA Pain Medicine Boards with:
PainExam Podcast Show Notes NAD+ Supplementation in Pain and Inflammation: Hype, Hope, or Emerging Science? Hosted by: PainExam Podcast Presented by: NRAP Academy (Neuromodulation, Regional Anesthesia & Pain) Host: David Rosenblum, MD Episode Overview In this episode of the PainExam Podcast, we explore the growing interest in NAD+ (Nicotinamide Adenine Dinucleotide) supplementation and its potential role in pain management, inflammation reduction, cellular recovery, and healthy aging. NAD+ is a naturally occurring coenzyme found in every living cell and is essential for energy production, mitochondrial function, DNA repair, and cellular resilience. As NAD+ levels decline with age, chronic stress, inflammation, and disease, researchers have begun investigating whether restoring NAD+ levels may improve outcomes in chronic pain conditions and inflammatory disorders. We review the current science, discuss potential mechanisms of action, and examine how NAD+ therapy is being integrated into regenerative medicine, wellness programs, and pain management practices. What is NAD+? NAD+ is a coenzyme involved in: ✅ Cellular energy production (ATP generation) ✅ Mitochondrial health ✅ DNA repair pathways ✅ Oxidative stress reduction ✅ Neuroprotection ✅ Cellular signaling ✅ Activation of longevity-associated proteins called sirtuins Without adequate NAD+, cells become less efficient at producing energy and managing inflammation. Why Might NAD+ Matter in Chronic Pain? Many chronic pain conditions involve: Mitochondrial dysfunction Oxidative stress Neuroinflammation Peripheral and central sensitization Impaired cellular recovery Researchers hypothesize that optimizing NAD+ levels may help address several of these pathways simultaneously. Potential areas of interest include: Neuropathic Pain NAD+ may support: Nerve repair Axonal recovery Mitochondrial function within neurons Reduction of oxidative injury Inflammatory Pain NAD+ influences inflammatory signaling pathways and may help modulate: Cytokine production Immune cell activity Cellular stress responses Fatigue and Recovery Patients with chronic pain frequently report: Fatigue Brain fog Reduced exercise tolerance Poor recovery Because NAD+ plays a critical role in energy metabolism, some clinicians report improvements in energy and recovery following supplementation. Potential Mechanisms of Action 1. Improved Mitochondrial Function Mitochondria generate ATP, the body's energy currency. Reduced NAD+ levels are associated with: Cellular aging Impaired energy production Increased inflammation Supplementation may help restore mitochondrial efficiency. 2. Activation of Sirtuins Sirtuins are proteins involved in: Cellular repair Longevity Metabolic regulation Inflammation control NAD+ serves as a critical substrate for sirtuin activity. 3. DNA Repair Support NAD+ is required for enzymes known as PARPs (Poly ADP Ribose Polymerases), which participate in DNA repair processes following cellular injury. 4. Reduction of Oxidative Stress Chronic inflammation often produces excessive reactive oxygen species (ROS). NAD+ may help maintain cellular antioxidant defenses and reduce oxidative injury. Routes of NAD+ Supplementation Intravenous (IV) NAD+ Most commonly marketed in wellness and recovery clinics. Potential advantages: Direct systemic delivery Avoids gastrointestinal absorption issues Allows higher dosing protocols Potential limitations: Cost Time commitment Variable evidence base Oral Precursors Rather than NAD+ itself, many supplements provide precursors such as: Nicotinamide Riboside (NR) Nicotinamide Mononucleotide (NMN) These compounds are converted into NAD+ within the body. What Does the Evidence Show? Current evidence remains preliminary. While preclinical and mechanistic studies are promising, large-scale randomized controlled trials evaluating NAD+ specifically for chronic pain are still limited. Areas under active investigation include: Neuropathic pain Neurodegenerative disorders Chronic fatigue syndromes Recovery optimization Healthy aging Patients should understand that NAD+ therapy remains an emerging treatment rather than a standard evidence-based pain intervention. Safety Considerations Reported side effects may include: Nausea Flushing Chest tightness during rapid infusions Headache Fatigue Lightheadedness Most adverse effects appear infusion-rate dependent and can often be minimized through slower administration protocols. Patients should discuss treatment with a qualified healthcare professional, especially if they have: Cardiovascular disease Active cancer Significant medical comorbidities Clinical Pearls for Pain Physicians ✔ Consider NAD+ as a potential adjunct—not a replacement—for evidence-based pain care. ✔ Continue emphasizing exercise, sleep optimization, nutrition, behavioral health, and appropriate interventional therapies. ✔ Discuss realistic expectations with patients. ✔ Recognize that evidence continues to evolve. ✔ Focus on patient-centered outcomes rather than laboratory markers alone. Key Takeaways NAD+ is essential for cellular energy production and repair. Declining NAD+ levels may contribute to aging, inflammation, and chronic disease. Early evidence suggests possible benefits in inflammation, recovery, fatigue, and nerve health. Robust pain-specific clinical trials remain limited. NAD+ therapy should currently be viewed as an adjunctive and investigational strategy in pain management. Resources for Physicians Pain Medicine Board Preparation Prepare for the ABA Pain Medicine Boards with:
Ella Farlinger is the Co-Founder of trusti. We reflect on the growth... The post Pride Rewind: Sex, Health and Stigma Reduction with Ella Farlinger first appeared on Startup Canada.
Why would God reduce Gideon's army when the enemy was so large they couldn't even be counted?In this message from Judges 7, Pastor Jim Schultz walks through the famous story of Gideon and the 300 men, showing that God's goal was never military strategy—it was revealing a deeper truth. God reduced the troops so that everyone would know the victory belonged to Him alone.Along the way, we'll see God's patience and grace toward Gideon, the danger of trusting signs more than God's Word, and the temptation we all face to take credit for what God has done. This passage reminds us that God's power is often displayed through human weakness and that our confidence is never meant to rest in ourselves.Whether you're studying the Book of Judges, looking for encouragement in a difficult season, or wanting to grow in your trust in God's promises, this sermon points us back to the God who saves, provides, and deserves all the glory.
Dr Amelia Harry is an experienced Advanced Accredited Practising Dietitian, Accredited Nutritionist, and plastics, diet & human health researcher. In this chat, we discuss the latest publication (in Nature Medicine) that Dr Amelia co-authored on the results of the Plastic Exposure Reduction Transforms Health (PERTH) Trial - which assessed phthalates and bisphenols in humans and what impact a change in diet had. We discuss the methodology, results (it's good news !!) and how you can minimise plastic ingestion in your own life (and why you should).Useful links:Dr Amelia on LinkedIn (here)eatsustainably.com.auJournal paper, Low-plastic diet and urinary levels of plastic-associated phthalates and bisphenols: the randomized controlled PERTH Trial (here) Hosted on Acast. See acast.com/privacy for more information.
Linktree: https://linktr.ee/AnalyticJoin The Normandy For Ad-Free NME, Additional Bonus Audio And Visual Content For All Things Nme+! Join Here: https://ow.ly/msoH50WCu0K In this segment of Notorious Mass Effect, Analytic Dreamz breaks down the latest reports on Bungie's rumored major layoffs in summer 2026 following the official end of Destiny 2's active development.Analytic Dreamz examines claims that up to 50% of Bungie's roughly 800–850 staff could be cut, potentially affecting 400 employees. The discussion covers multiple sources including Sylvain Trinel and Paul Tassi, the $765 million Sony impairment loss, the shift of resources to Marathon, and the timing of expected leadership departures in July 2026 after vesting payouts.This segment also explores Destiny 2's final update Monument of Triumph, the surge in player numbers, the growing Destiny 3 petition nearing 400,000 signatures, Bungie's previous 2024 layoffs, and broader PlayStation studio restructuring. Analytic Dreamz provides context on Sony's 2022 acquisition, Marathon's performance concerns, and what this means for the future of one of gaming's most iconic studios.Essential listening for Destiny fans and industry watchers tracking the latest Bungie and Sony developments. Privacy & Opt-Out: https://redcircle.com/privacy
In this episode of Keeping Abreast, Dr. Jenn Simmons responds to Peter Attia's breast cancer screening episode (#396). Attia asks the right question: why are 42,000 women still dying of breast cancer every year? But his answer, more mammograms and MRI on top, is exactly wrong. Dr. Jenn breaks down, study by study, why that 40-year approach has never moved the death toll.Forty-two thousand women a year. That number has not moved since mammography went mainstream in the 1980s. Detection rates are up, diagnoses are up, and the death toll has not changed. We have been finding more cancer, calling more women patients, and watching the same number of them die. If you have ever scheduled your annual mammogram believing it was the most protective thing you could do, this episode will reframe everything you thought you knew.What You'll LearnWhy the breast cancer death toll has not moved in 40 years, and why more screening is the reasonWhy DCIS is not cancer, why mammography invented it, and what happens to a woman the moment it gets labeled "stage zero"Why an aggressive tumor is aggressive from the day it forms, and why finding it earlier on a mammogram does not change what it does nextWhy mammography catches the cancers least likely to kill you, and routinely misses the ones that willWhat happened when researchers followed 89,835 women for 25 years and compared annual mammography to doing nothing, and why you have never heard about itWhat the Cochrane review found after analyzing every randomized mammography trial ever run, and why Peter Attia addressed it in one sentenceWhy the WISDOM trial, the most significant recent evidence in this space and the one study Attia never mentions, is an indictment of everything he arguedWhy there is no standard radiation dose for a mammogram, and why the woman next to you in the waiting room may have received ten times less than you didWhat the FDA has formally documented about gadolinium staying in the brain and bones for years, and why the women being told to get it every six months are the last women who shouldWhy insulin resistance, chronic inflammation, and toxic burden are among the most powerful drivers of breast cancer risk, and why Attia's episode contained zero mention of any of themResources MentionedPeter Attia, Episode 396 on breast cancer screening: peterattiamd.com/breastcancerscreeningDr. Robin Berzin, founder of Parsley HealthMiller AB, et al. Twenty five year follow-up of the Canadian National Breast Screening Study. BMJ. 2014;348:g366.Gøtzsche PC, Jørgensen KJ. Screening for breast cancer with mammography. Cochrane Database Syst Rev. 2013;(6):CD001877.Zahl PH, et al. Results of the Two-County trial are not compatible with official Swedish breast cancer statistics. Danish Medical Bulletin. 2006;53(4):438–440.Nyström L, et al. Long-term effects of mammography screening: updated overview of the Swedish randomised trials. Lancet. 2002;359:909–19.Esserman LJ, et al. Risk-Based vs Annual Breast Cancer Screening: The WISDOM Randomized Clinical Trial. JAMA. 2026;335(9):763–774.FDA gadolinium-based contrast agent safety communications (2015, 2017, 2018), summarized in Fotenos A, FDA Pediatric Advisory Committee, Sept 2018.Kanda T, et al. High signal intensity in the dentate nucleus and globus pallidus and cumulative gadolinium dose. Radiology. 2014;270(3):834–841.Veenhuizen SGA, et al. Supplemental breast MRI for women with extremely dense breasts: DENSE trial. Radiology. 2021;299(2):278–286.Tabar L, et al. Reduction in mortality from breast cancer after mass screening with mammography. Lancet. 1985;325:829–32.To talk to a member of Dr. Jenn's team and learn more about working privately with Dr. Jenn visit: https://calendly.com/stephanie-1031/clarity-callTo get your copy of Dr. Jenn's book, The Smart Woman's Guide to Breast Cancer, visit: https://tinyurl.com/SmartWomansBreastCancerGuideTo purchase the auria breast cancer screening test go here https://auria.care/ and use the code DRJENN20 for 20% Off.Connect with Dr. Jenn:Website: https://www.jennsimmonsmd.com/Facebook: https://www.facebook.com/DrJennSimmonsInstagram: https://www.instagram.com/drjennsimmons/YouTube: https://www.youtube.com/@dr.jennsimmons
International Bankruptcy, Restructuring, True Crime and Appeals - Court Audio Recording Podcast
After nearly three decades of public service, Shelby shares her experience navigating a Reduction in Force (RIF), the grief that follows career loss, and the challenge of rebuilding professional identity after an unexpected transition.In this candid coaching conversation, Belinda and Shelby explore what it means to process professional grief, move forward without bitterness, and build confidence in the face of uncertainty.They discuss leadership during difficult seasons, the importance of community, and why resilience often begins by remembering the challenges you've already survived.In this episode:Professional grief and career lossLeadership during personal transitionRebuilding confidence after a layoffIdentity shifts and reinventionCoaching, therapy, and resilienceFaith, community, and healingMoving from reflection to actionIf you're navigating a career transition, organizational change, retirement, or an unexpected life pivot, this conversation offers practical wisdom and encouragement for the road ahead.--------------------Our company, Grounded and Global Advisory, is pleased to offer a quarterly advisory retainer. For $275 per month (billed quarterly, with the option to renew each quarter), you'll receive:One 60-minute coaching session per monthPriority access to our calendarOne annual 90-minute strategic intensiveThis offer is for the person who knows what good advisory support feels like and doesn't want to lose it. Spots are limited. If you're interested, email us directly at hello@stirringsuccess.com, and we'll be in touch.Send us a comment!Support the showWe publish new episodes every other Wednesday.Subscribe to the Leadership Tea PodcastSubscribe to Leadership Tea on YouTube!Follow us on Instagram @Leadership_Tea for more inspiration and insights.
The annual Nepal Festival Darwin is being held this Saturday, 13 June, at the usual Darwin Waterfront. SBS Nepali spoke with Trilochan Sapkota of the Non-Resident Nepali Association of Northern Territory (NRNA-NT) about how this year's event will differ and what attendees can expect. - गैर-आवासीय नेपाली सङ्घ अस्ट्रेलिया - नर्दन टेरेट्रीको आयोजनामा भोली शनिवार, जुन १३ मा डार्विन स्थित वाटरफ्रन्टमा हुन गइरहेको नेपाल फेस्टिभल २०२६ का बारेमा एनआरएनए एनटी संयोजक त्रिलोचन सापकोटासँग एसबीएस नेपालीले गरेको कुराकानी सुन्नुहोस्।हाम्रा थप अडियो प्रस्तुतिहरू पोडकास्टका रूपमा उपलब्ध छन्। यो नि:शुल्क सेवा प्रयोग गर्न तपाईंले आफ्नो नाम दर्ता गर्नु पर्दैन। पोडकास्टमा सामाग्री उपलब्ध हुनासाथ सुन्न यहाँ थिच्नुहोस्।नोट: हामी तपाईँलाई जानकारी गराउन चाहन्छौँ कि यस कुराकानीमा व्यक्त गरिएका विचारहरू वक्ता स्वयम्का हुन् र यी विचारहरू प्रति एसबीएसको समर्थन वा विरोध छैन।थप सुन्नुहोस्
How can targeted liver radiation unlock surgical or transplant options for tough hepatocellular carcinoma (HCC) cases? In this episode of BackTable 2026 HCC Creator Weekend™ host Dr. Kavi Krishnasamy is joined by interventional radiologists Dr. Beau Toskich and Dr. Chris Malone to explore how downstaging and radiation lobectomy with Y-90 are creating new surgical and transplant opportunities for patients with limited future liver remnants. They discuss Y-90's role as a “test of time” for tumor biology, strategies to prevent post-hepatectomy liver failure, and the ongoing challenge of recurrence even after R0 resection in cirrhotic livers. --- Get the BackTable apphttps://www.backtable.com/app --- This podcast is supported by an educational grant from Sirtex and Boston Scientific. --- Timestamps 00:00 - Introduction01:31 - Rad Lobectomy Goals and Case Discussion06:09 - Selective vs Lobar Dosing07:51 - PVE Versus Y9009:35 - Downstaging to Transplant13:03 - Patient Selection Factors19:22 - Radseg vs. Lobar Strategy22:12 - Percent Liver Treated Debate26:38 - Particle Density and Catheter Bias28:04 - Downstaging Evidence MERIT LT36:20 - Operating After Y9041:25 - Hypertrophy Timing and Readiness43:03 - Wrap Up --- More about this episode The discussion features a case of massive right-lobe HCC in a non-cirrhotic patient, with stepwise Y-90 dosing and selective retreatment leading to complete response and marked liver hypertrophy. The doctors compare radiation lobectomy with portal vein embolization (PVE), explore dosimetry advances from studies like DOSISPHERE and MERITS-LT, and stress the importance of careful mapping and patient selection. Additional topics include the pros and cons of different downstaging methods, functional imaging to assess risk, the impact of lab values and portal hypertension, and the practicalities of timing surgery after Y-90. --- Resources Long-Term Overall Survival After Selective Internal Radiation Therapy for Locally Advanced Hepatocellular Carcinomas: Updated Analysis of DOSISPHERE-01 Trialhttps://jnm.snmjournals.org/content/early/2024/01/10/jnumed.123.266211 Downstaging hepatocellular carcinoma before liver transplantation: A multicenter analysis of the "all-comers" protocol in the Multicenter Evaluation of Reduction in Tumor Size before Liver Transplantation (MERITS-LT) consortiumhttps://pubmed.ncbi.nlm.nih.gov/37532179/ --- BackTable Vascular & Interventional (VI) is the go-to podcast for interventional radiologists, vascular surgeons, and interventional cardiologists. Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty. ► https://www.backtable.com/app
In this episode of the Essential Wellness Podcast, Aisha Harley and the Oils A to Z panel explored Shinrin Yoku, doTERRA's Japanese Forest Bathing Blend, also known as the "Oil of Immersion." Joined by Will Wan, Dr. Louise Rose, Dr. Mika Carew, and Arianna Harley, the discussion uncovered the blend's physical, emotional, energetic, and Traditional Chinese Medicine benefits. The panel explained how Shinrin Yoku combines powerful botanicals including citrus oils, patchouli, magnolia leaf, Siberian fir, cardamom, cypress, lavandin, and geranium to support nervous system regulation, emotional grounding, and overall wellness. They also explored the science behind forest bathing and shared practical ways to incorporate the blend into daily routines for greater calm, presence, and resilience.
Hour 1 of the Chris Hand Show | Aired Thursday 06-04-36See omnystudio.com/listener for privacy information.
What happens when a split-second accident changes the way you see yourself for more than a decade?In this episode of Plastic Surgery Uncensored, I sit down with Jasmine, a former Navy service member who spent 11 years living with a traumatic lip deformity after a sports injury involving braces. What began as a seemingly routine injury left her with permanent changes to her lip shape, affecting her confidence, smile, photos, and daily interactions for years.Together, we explore a topic rarely discussed in plastic surgery: lip reduction and corrective lip reconstruction. While the world is flooded with information about lip fillers and lip augmentation, very few patients know that surgical solutions exist for traumatic lip deformities, scar tissue, and post-injury asymmetries. In this episode, we discuss:• How lip trauma can permanently alter lip shape• Why many patients struggle for years to find answers• The difference between cosmetic enhancement and reconstructive surgery• The emotional burden of living with a visible facial deformity• Who may be a candidate for lip reduction surgeryJasmine's story is a powerful reminder that even a seemingly small physical concern can have a profound impact on confidence, self-image, and quality of life. And sometimes, the right solution is closer than you think.✨ If you enjoyed this episode of Plastic Surgery Uncensored:✔️ Subscribe on Apple Podcasts, Spotify, or wherever you listen.✔️ Rate & Review—your feedback helps more people find us.✔️ Follow Dr. Rady Rahban across all platforms for daily insights, behind-the-scenes, and patient education:Instagram: @drradyrahbanTikTok: @radyrahbanMDYouTube: @Rady RahbanFacebook: @Rady Rahban✔️ Share this episode with someone considering plastic surgery—the right knowledge can save a life.
DAMIONCarnival Corporation's data breach exposed personal data of nearly 6 million customers: An April social engineering attack on an employee account compromised names, dates of birth, and government-issued ID numbers. WHO DO YOU BLAMESkills: Technology & Cybersecurity: Experience with information technology and cybersecurity matters is increasingly important to mitigate the risks our business faces, promote innovation and maintain a competitive edge in a rapidly evolving technological ageLeast represented 5/11CEO Josh WeinsteinNO: at Carnival since 2002, started as General CounselSir Johathon BandNO: First Sea Lord and Chief of Naval Staff, the most senior officer position in the British Navy (2006 to 2009, when he retired); Admiral and Commander-in-Chief Fleet (2002 to 2006); Served as a naval officer in increasing positions of authority (1967 to 2002)Jason CahillyNO: CEO Dragon Group LLC, provides capital and business management consulting and advisory services worldwide; The NBA: CFO & Chief Strategic Officer; Goldman Sachs: Partner; Global Co-Head of Media and Telecommunications; Head of Principal Investing for Technology, Media & TelecommunicationsNelda ConnorsNO: CEO/Chair Pine Grove Holdings, a privately held investment company; CEO Atkore International, manufacturer of electrical, safety and infrastructure solutions; VP Eaton Corporation, electrical and automotive supplierLaura WeilNO: Founder Village Lane Advisory LLC, specializes in providing executive and strategic consulting services to retailers COO New York & Company, women's apparel and accessories retailer; CEO Ashley Stewart, women's apparel retailer; CEO Urban Brands, apparel retailer; COO AnnTaylor Stores, women's apparel retailer; CFO American Eagle Outfitters, apparel retailerAudit Committee: Oversee management's risk assessment processes to identify principal and emerging risks, including financial, IT, cybersecurity and non-HESS operational risksLaura Weil*: NOJason Cahilly: NOJeffrey Gearhart: NOWalmart Corporate Secretary and lawyerStuart Subotnick: NOCEO at Metromedia Company, wireless/communications, until 2010; Carnival director since 1987 Health, Environmental, Safety and Security Committee: Oversee management's processes to identify principal and emerging health, environmental, safety, security and sustainability-related risks, including those related to ship operations and cybersecurity, RAAS health, environmental, safety, security audits, IAG and external investigations into significant ship incidents, and health, environmental, safety, security-related hotline complaints, and assess the steps management has taken to minimize such risks.Sir Johathon Band*: NONelda Connors: NOHelen Deeble: NOFormer CEO P&O Ferries Division Holdings, shipping and logistics businessKatie Lahey: NOExecutive Chair Korn Ferry Australasia, leadership and talent firmMicky Arison (75%): Exec Chair and former CEO and 7% stockholderThe CEO Pay Ratio1,063:124 retail CEOs made as much in a day as their typical employee earned in a year — and a big one didn't. WHO DO YOU BLAMEThe separation of CEO and Chair: Hamilton E. James Chair/Ron Vachris MMNot uniqueOnly 50% of the board is men. WTF?uniqueOne share = one voteNot uniqueState of HQ = WashingtonAlso StarbucksState of Inc = WashingtonAlso StarbucksPledge of allegiance to stakeholdersCostco generally has: Higher wages; Better benefits; Lower turnover; Higher sales per employee.Industry-leading employee compensation AND Self-imposed low-margin pricing philosophyWalmart only low-margin pricingOther comps:Todd Vasos of Dollar General, Shane O'Kelly of AutoZone, Gerald Morgan of Texas Roadhouse, Jack Sinclair of Sprouts Farmers Market, William Stengel of Genuine Parts Company, Michael Creedon of Dollar Tree, Ronald Sargent of Kroger, Lauren Hobart of Dick's Sporting Goods, Joshua Kobza of Restaurant Brands Inc., Kecia Steelman of Ulta Beauty, Scott Boatwright of Chipotle, Ted Decker of Home Depot, Bob Eddy of BJ's Wholesale Club, Corie Barry of Best Buy, James Conroy of Ross Stores, Chris Turner and David Gibbs of Yum Brands, Chris Kempczinski of McDonald's, Marvin Ellison of Lowe's, Brian Cornell of Target, Ernie Herrman of TJX Companies, Doug McMillon of Walmart, Brian Niccol of Starbucks, Hal Lawton of Tractor Supply Co, Laura Alber of Williams-SonomaFigma Gets an Activist Investor. Exhibit A on Why Companies Don't Want to Go Public. Figma's first year as a public company hasn't gone well. Findell Capital Management said it needs to take steps to shed its unwarranted reputation as an artificial-intelligence “loser.” WHO DO YOU BLAME?Figma founder and CEO Dylan Field: Owns 10% of shares but 72% of voting power: Class B shares worth 15 votes per shareDylan owns 158 Class A Shares (or 0.00003556% of 444,278,887)And Chair$5B net worth$865M total summary compensation in 2025; $91M in 2024Nominating Agreement:Figma must nominate Dylan Field to be a director and include him in the proxy statementThe company must use its resources to back him up and actively convince other shareholders to vote for him In response to a question about how he was going to change the world, Dylan said he was going to build better software for drones.Bro fest sausage party2 of 9 directors are womenTop 5 NEOs all dudesPeter ThielForced Dylan to drop out of Brown for a dumb fellowshipVC Blowhardiness on the BoardVC dude John Lilly (Greylock): Lead Independent Director2nd longest tenure (2014)Member of the Audit Committee; Member of the Nominating Committee (only Lilly and Rimer)VC dude Andrew Reed (Sequoia)Director at debt-maker Klarna Group (also way down since IPO): down roughly 54% from its initial $40.00 IPO price, and down nearly 68% from its all-time highMember of the Compensation Committee (which modeled Dylan's pay package after Elon Musk)VC dude Danny Rimer (Index Ventures)Director since 2014B.A. in History and Literature from HarvardMember of the Compensation Committee (which modeled Dylan's pay package after Elon Musk)Member of the Nominating Committee (only Lilly and Rimer)Luis von AhnDuolingo co-founder and CEO2025: shared an internal email outlining Duolingo's new "AI-first" strategy where Duolingo would “gradually stop using contractors to do work that AI can handle”Stated that "AI is a better teacher than humans" and that the future role of teachers would be reduced to providing "childcare."Blamed the controversy on a "lack of context" in his original statements"AI-First" memo goes viral: $389; today $118MATTDanone, Starbucks shine in methane-reduction rankingDanone is the only company in the group aligned with the Global Methane Pledge, an initiative backed by 150 countries that targets a 30 percent reduction in global levels of the gas by 2030. The French multinational also leads the pack in progress toward its target, having come close to hitting it five years ahead of schedule.WHO DO YOU CREDIT?Chair of the CSR committee Lise Kingo (9% influence), one of three directors tagged as merit directorsmaster's degree in Responsibility & Business from the University of Bathbachelor degrees in Religions and Ancient Greek Artbachelor's degree in Marketing and Economicscertificate as International Director from INSEADEx Novo Nordisk environmental affairs, internal audit, compliance, human resources, communication, branding and sustainabilityHelped create the UN SDGs and the UN Global CompactSomehow only bats 559 on carbon intensity (career) and 415 for scope 1/2 (career)Also, using deference metrics, the ONLY DIRECTOR tagged as fully independentEmployee rep member of the CSR committee Bettina Theissig (5% influence) and the employees of DanoneThe committee charter mandates employees get a say: At least two thirds of the CSR Committee must be independent, as defined by the AFEP-MEDEF Code. At least one Director representing employees must be a member of the Committee.In France (Danone's domicile), the European Investment Bank found that French employees were the most aware of environmental issues - 82% of French employees said they were highly concerned about environmental issues, highest in EuropeLead Independent Director and chair of the Nom/comp committee who put together the comp plan, Valerie Chapoulaud-Floquet15% influence, second to the 18% influence CEO (democracy!!), got 99.16% shareholder approval in April (even as CEO got 89.73% approval and pay got 93.19% approval)20% of short-term pay and 30% of long-term pay is based on hitting sustainability targetsWhen you pay a CEO to do a thing, they are more likely to do a thingEx-CEO Emmanuel FaberOusted in 2021 by the board of directors and activist investors, he transformed Danone into an “enterprise a mission” (a French version of a B corp)Investors voted 99% in favor of the move and a year later ousted Faber, the board resigned, and the new board and CEO are basically moving back towards being environmental leaders because it paid offShort term share price laggedHe said in 2024 that nature is “at the core” of Danone, It took the stock 3 years from Faber's ousting to return to Faber levels - and in the meantime, they were sued for plastics and emissionsIsn't this HIS win?Current CEO Antoine de Saint-AffriqueBecause CEOGM Board Director Jonathan McNeill Stepping DownCEO of DVx Ventures. Ex COO at Lyft Inc. and ex president, Global Sales, Delivery and Service at Tesla, current director at Lululemon, GM director since 2022, on the Governance and Corporate Responsibility committee and Risk and Cybersecurity committee.We know that half of boards on average think someone on the board should be replaced - did the GM board not like McNeill?WHO/WHAT WOULD WE BLAME FOR PUSHING MCNEILL OUT?Outsider dude bro DRLet's be honest, McNeill worked at much more… modern?... companies than GMThe board is OLD SCHOOL - ex Northrop Grumman, ex Visa, ex Lazard, ex HP, ex eBay, ex Novartis, ex Walmart, other directorships at Goldman, Huntsman, P&G… these are professional, insular boardsMeanwhile, he's investing as a VC in AI, other auto/mobility startups, comes from boards that are bro founder lead (Tesla, Lyft) He's invested in AI, crypto, heavy tech, intertwined with VCs all overNot deferential enoughBarra is connected to 94% - THE ENTIRE - boardMcNeill has the highest network power on the board at $9tn, higher than even Mary Barra (who is super connected), but is NOT a power player in the board community of GM - the dominant board communities for GM are massive blue chip US companies, where McNeill has deeper connections in smaller IT/tech focused companiesHe doesn't need the pay, he gets nothing for the connections really, he has connection to Barra but his network is different - was he too independent?Pissed he doesn't have enough influence McNeill has the LOWEST influence on the GM board at 4%He's relatively new, younger, working as a VC where you have a lot of power of capital allocation“I don't need this shit” effect?Too many womenMcNeill's dvX ventures portfolio team is 6 dudes and 1 womendvX entire operations staff is two woman - guess what they do“Chief of Staff” (ie, HR)Executive Assistant (yes, listed on the team)Board is 2 women, 3 men (McNeill not on board)This one seems unlikely I guess?Too busy, meh, move onOne of dvX portfolio companies is curbee, with GM Ventures' Kurt Baumgarten on the board (and the dvX co-founder is founder of Curbee)McNeill on at least 3 of his portfolio boards or advisory committees, plus LULU and GM…
The 3Rs of animal research (Replacement, Reduction, Refinement) are truly a global effort. One of the experts leading this effort is veterinarian Adrian Smith, Secretary of the Norwegian organization Norecopa. Along with Executive Director Global Animal Welfare and Training for Charles River Liz Nunamaker, they share the creation and growth of Norway's National Consensus Platform and Centre for furthering the 3Rs, and how even researchers outside of Norway like Nunamaker benefit from its work.
4:20 pm: Kevin Downey, Jr., a host on LI News Radio in Long Island, New York and a contributor to PJ Media, joins the show for a conversation about is piece on how even “blue” cities are tiring of the antics of “woke” Democrats.4:38 pm: Jay Rogers, Founder and President of Alpha Strategies and a contributor to Townhall, joins the program to discuss his piece reminding Americans to never forget those behind the covid craziness.5:05 pm: Utah Senate President Stuart Adams joins Rod and Greg to discuss the letter he sent to Kevin O'Leary calling for a 75% reduction in the footprint of the proposed data center in Box Elder County, along with asking for a greater focus on land conservation and water stewardship.6:38 pm: Jeffrey H. Anderson, President of the American Main Street Initiative, joins the program to discuss his piece for the City Journal about the victories earned by President Trump when it comes to border control.
Three Things That Escaped the Savannah Convention CenterLuke Carignan and ASHHRA Executive Director Jeremy Sadlier are back from ASHHRA26 — and the sessions were too good to leave at the convention center. Bo is out this week, but the content more than covers for it. Three themes from the conference floor that every healthcare HR leader needs on their radar right now.
Scotty G. & The Coach with Scott Garrard and Tim LaComb on June 1, 2026. Hour 1 Starting Lineup Party like it's 1999: Spurs vs Knicks NBA Final What You May Have Missed Hour 2 Shehan Jeyarajah, college Football writer for CBS Sports G, B & U: Browns and the Rams finalizing Myles Garrett blockbuster trade Biggest Pet Peeves Hour 3 Latest on Utah's private equity deal with Otro Capital Final details released on the Myles Garrett trade NEW Guinness World Records title for the most takeaway dishes memorised in 30 seconds Hour 4 Spurs-Knicks; Knicks being physical on defense Greg Wyshynski, senior NHL writer for ESPN + MORE
Hour 3 of Scotty G. & The Coach with Scott Garrard and Tim LaComb. Latest on Utah's private equity deal with Otro Capital Final details released on the Myles Garrett trade NEW Guinness World Records title for the most takeaway dishes memorised in 30 seconds
Are you considering a breast reduction or a breast lift but feel completely overwhelmed by all the medical jargon online? In this episode of Big Butts No Lies, Mavi sits down with board-certified New York City plastic surgeon Dr. Keith Blechman to demystify everything you need to know about breast surgery. Dr. Blechman strips away the confusing terminology and breaks down breast anatomy into two simple parts: the skin envelope and the breast mound. We dive into the critical differences between a medically necessary breast reduction (which relieves chronic back pain, neck strain, and bra grooving) and a cosmetic breast lift for deflated or saggy breasts after pregnancy or rapid weight loss. Dr. Blechman also pulls back the curtain on his revolutionary, drain-free recovery protocol and a specialized rib cage nerve block technique that allows over 90% of his patients to recover without any prescription narcotic painkillers. Plus, we explore the step-by-step reality of gender-affirming top surgery, what to realistically expect regarding nipple sensation trade-offs, and how to properly vet your surgeon so you are always in safe hands.⏱️ In this episode:00:00 — Introduction to Dr. Keith Blechman 01:15 — Why I Chose Plastic Surgery 05:07 — The Recovery Diaries Promo05:44 — How to Choose the Right Surgeon 09:26 — The Real Difference: Breast Lift vs. Reduction 14:02 — Is a Breast Reduction Medically Necessary? 16:43 — Let's Talk About Surgical Scars 19:49 — Nipple Sensation & Numbness Risks 23:05 — Can You Breastfeed After a Reduction? 24:21 — Gender-Affirming Top Surgery Explained 28:10 — Crucial Advice for Your Surgery Journey 30:01 — The Drain-Free Recovery Revolution 30:51 — How We Eliminated Prescription Narcotics
Charles Burton examines Canada's controversial economic pivot toward China, where Prime Minister Mark Carney is pursuing a strategic partnership that includes non-public security agreements and the reduction of tariffs on Chinese electric vehicles. Critics warn these moves compromise Canadian sovereignty and allow for significant Chineseinfiltration. (7)1900
In early May 2026, transport vans rolled out of Ridglan Farms in Blue Mounds, Wisconsin, carrying beagles toward new lives—grass under their paws, sunlight on their faces, and homes instead of stacked wire cages. Nearly 1,500 beagles were purchased by rescue organizations like Big Dog Ranch Rescue and the Beagle Freedom Project after years of documented suffering at one of the nation's largest commercial beagle breeders for biomedical research. This outcome marks a rare, tangible win for animal advocates. But it came only after daring direct-action raids, mass protests met with tear gas and rubber bullets, a special prosecutor's investigation, and persistent legal pressure. Even now, roughly 500 dogs may remain behind as Ridglan winds down its commercial breeding operations by July 1, 2026. The Ridglan story is not just about one facility. It exposes deep, systemic failures in U.S. law that leave millions of animals in laboratories with minimal protections—and even those “covered” by federal rules often receive little meaningful relief. The Raids That Forced Change On March 15, 2026, activists from groups linked to the Coalition to Save the Ridglan Dogs breached fences and buildings at Ridglan Farms. They removed around 22–30 beagles. Some were successfully rehomed; others were recovered by police. However, an estimated 2000 beagles remained in captivity, potentially subject to additional horrific experimentation. Our guest, Dean Guzman Wyrzykowski, was one of these activists. A second, larger action on April 18 drew roughly 1,000 protesters to rescue the remaining beagles. Law enforcement responded with tear gas, pepper spray, and rubber bullets. No additional dogs could be rescued that day. Dozens of protesters were arrested, including our guest on The Breggin Hour, Dean Guzman Wyrzykowski, a San Francisco Bay Area-based animal rights activist and political organizer. He is co-founder of The Simple Heart Initiative—a nonprofit dedicated to advancing species equality through open rescue, impact litigation, undercover investigations, and activist training. With over eight years in nonprofit advocacy, Dean has recruited and trained hundreds of activists and is one of the lead organizers of the Ridglan campaign. He now faces serious felony burglary charges—potentially up to 12 years in prison—along with several co-defendants for the first March 15, 2026, rescue effort. Further charges may be pending. As a top priority, we urge that the charges be reduced or dropped to reflect the vastly important ethical basis of the actions of these animal advocates. How to Help Dean Dean reports that the best way to assist him with legal costs is to become a paid subscriber to his Substack at Urbananimal.substack.com. To support ending the breeding of dogs for lab testing, go to Save the Dogs, make a donation, and join over 111,581 others who have already signed the petition to end breeding of dogs for laboratory use. These weren't the first efforts to expose and stop the abuses of these dogs. Ridglan had faced scrutiny for years, including earlier investigations. The raids amplified public outrage and accelerated negotiations between rescuers and Ridglan Farms. In late April, rescue groups announced they had reached a deal to acquire ~1,500 dogs. Transports began in early May, with many “frosted face” seniors (older dogs with graying muzzles) now adjusting to life outside the facility—initially flinching at touch but quickly learning to wag tails and play. Decades of Alleged Cruelty at Ridglan — and Why It Is Winding Down Ridglan Farms operated for decades as a major supplier of beagles for testing. Former employees and state inspections described windowless warehouses, stacked cages over waste pits, high ammonia levels, rusted wires causing injuries, and routine surgeries (including eye procedures and devocalizations) performed without anesthesia or proper pain relief—sometimes by non-veterinarians. In 2025, Wisconsin's Department of Agriculture, Trade and Consumer Protection (DATCP) cited Ridglan for hundreds of violations. A judge found probable cause for animal cruelty. Special Prosecutor Tim Gruenke was appointed to investigate. Rather than face criminal charges, Ridglan chose to wind down. In a negotiated settlement in late 2025, the company agreed to surrender its Wisconsin commercial dog-breeding license by July 1, 2026. This effectively ends its large-scale commercial breeding and sales of beagles to external laboratories. In exchange, the state dropped the threat of felony animal cruelty prosecutions. This agreement was driven by years of accumulated citations, whistleblower testimony, undercover investigations, and intense public and activist pressure. While Ridglan can still conduct limited on-site research under its federal USDA licenses, its days as a major commercial beagle supplier are over. Parallels with Envigo and Other Scandals Ridglan is far from isolated. In 2022, a major scandal erupted at Envigo's breeding facility in Cumberland, Virginia. PETA's undercover investigation revealed severe neglect: inadequate food, veterinary care, housing, and staffing; dead puppies were left among litters; and unqualified staff performed invasive procedures. The U.S. Department of Justice intervened, leading to the rescue of over 4,000 beagles—the largest such seizure in U.S. history. Envigo (and its parent company Inotiv) later pleaded guilty to conspiring to violate the Animal Welfare Act and the Clean Water Act, agreeing to pay a record $35 million+ in fines and shutting down the breeding operation. From the Beagles to the Breggins, Senator Bill Stanley Sought Justice for the Underdog At a state level, key Virginia state legislators were involved in advocating for stronger animal welfare regulations in response to documented Animal Welfare Act violations, poor conditions, and high puppy mortality in the facility. Sen. Bill Stanley (R-Franklin County) was a leading champion at the state level. He visited the facility multiple times, co-sponsored several “Beagle Bills” in 2022 (e.g., SB 87, SB 88, SB 90, SB 604) to increase oversight, close loopholes for research animals, require adoption offers before euthanasia, and penalize repeat violators. He adopted two Envigo beagles (Daisy and Dixie) and worked on adoptions/rescues. We are especially happy to acknowledge Sen. Stanley's contributions because, among several attorneys we contacted to defend us against Robert Malone's lawfare defamation suit against us for $25 million, Bill was the first attorney willing to seriously pursue our case, which ended in the presiding judge throwing Malone's case out of court. From the beagles to the Breggins, Senator Stanley has sought justice for the underdog. The Sand Fly Experiments and High-Profile Scandals Public outrage over government-funded beagle suffering peaked in the early 2020s with revelations about NIH-funded experiments under Dr. Anthony Fauci's National Institute of Allergy and Infectious Diseases (NIAID). One widely criticized study involved beagle puppies in Tunisia exposed to sand flies carrying parasites (to study leishmaniasis). Reports described dogs having their heads locked in mesh cages filled with infected sand flies, being used as live bait in desert cages overnight, and in some cases undergoing cordectomies (vocal cord removal) to silence barking. The experiments sparked bipartisan congressional criticism and intense media coverage. The Nonhuman Rights Project (NhRP) and partners filed habeas corpus petitions seeking court recognition of the Ridglan dogs' right to freedom from cruelty and immediate remedies. While initial petitions faced dismissal, appeals continue for the remaining animals. Why U.S. Law Fails Experimental Animals The core federal statute is the Animal Welfare Act (AWA) of 1966 (and its amendments), enforced by the USDA's Animal and Plant Health Inspection Service (APHIS). It sets minimum standards for housing, feeding, veterinary care, and handling of certain animals. Critical Limitations Include: Massive Species Exclusions: Rats, mice, and birds bred for research—accounting for roughly 95% of lab animals—are explicitly excluded. Cold-blooded animals and others also fall outside coverage. Weak Standards for Covered Species: Even for dogs, cats, primates, etc., the AWA permits painful procedures if deemed “scientifically necessary.” There is no outright ban on specific types of experiments. Self-Regulation via IACUCs: Institutional Animal Care and Use Committees—dominated by researchers at the institutions they oversee—review protocols. Approval rates hover near 98%, with limited external oversight. Enforcement Gaps: Under-resourced inspections, reliance on self-reporting, and modest penalties limit impact. Ridglan itself had passed many USDA inspections despite state-level findings of serious issues. Property Status: Animals remain legal property. Novel habeas efforts like the Nonhuman Rights Project (NhRP) challenge this but face significant judicial hurdles, as courts have historically rejected animal “personhood” claims. For those of us who learned in childhood about unconditional love from our dogs, they are not only of equal value to people, but they seem on a higher spiritual level in the love they have given to us. Other frameworks, such as the Public Health Service Policy, apply only to federally funded research and offer even less robust enforcement. The 2022 FDA Modernization Act opened doors to non-animal alternatives, but broader statutory mandates for the “3Rs” (Replacement, Reduction, Refinement) remain limited. Reform efforts often stall due to powerful research lobbies, congressional agriculture committees' oversight, and public support for medical research that can overshadow welfare concerns. Broader Context and the Path Forward Ridglan and Envigo show that systemic problems persist despite occasional rescues and fines. Millions of animals continue to be used annually in U.S. labs, yet positive developments exist: growing adoption of alternatives (organ-on-chip, AI modeling, human cell cultures), increased rehoming programs, and shifting public opinion favoring stronger protections. The Ridglan victory shows that sustained pressure—investigations, lawsuits, public protest, and direct rescue—can force change where law falls short. Yet relying on activists risking felony charges is not sustainable. Meaningful reform requires: Expanding Animal Welfare Act coverage to all vertebrates. Stronger, independent oversight and enforcement with real penalties. Mandatory consideration and funding for non-animal methods. Judicial tools (like effective habeas relief) to address cruelty in licensed facilities promptly. A Call to Readers The beagles now tasting freedom represent hope—but hundreds may still face uncertainty, and systemic issues persist for countless others. Share their stories. Support reputable rescues and organizations like The Simple Heart Initiative, the Nonhuman Rights Project, Beagle Freedom Project, and others working on legal and legislative fronts. Contact your representatives and demand real modernization of the Animal Welfare Act. Persistence works. Now we must translate outrage into lasting legal change—so no more facilities like this exist in the first place. What are your thoughts on balancing research needs with animal welfare? Have you followed the Ridglan story, the Envigo case, Dean's work, or the earlier sand fly scandals? Drop a comment or share this post. References / Endnotes Wisconsin Examiner / Milwaukee Journal Sentinel coverage of Ridglan rescues and settlement (2026). Nonhuman Rights Project – Ridglan Beagles case page. U.S. Department of Justice – Envigo sentencing and $35M+ resolution (2024). Bipartisan congressional letters on NIAID/Tunisia sand fly experiments (2021). Dean Guzman Wyrzykowski / The Simple Heart Initiative statements (2026). USDA Animal Welfare Act overview and limitations. Additional reporting from WPR, Right to Rescue, and related investigations. ______ Learn more about Dr. Peter Breggin's work: https://breggin.com/ See more from Dr. Breggin's long history of being a reformer in psychiatry: https://breggin.com/Psychiatry-as-an-Instrument-of-Social-and-Political-Control Psychiatric Drug Withdrawal, the how-to manual @ https://breggin.com/a-guide-for-prescribers-therapists-patients-and-their-families/ Get a copy of Dr. Breggin's latest book: WHO ARE THE “THEY” - THESE GLOBAL PREDATORS? WHAT ARE THEIR MOTIVES AND THEIR PLANS FOR US? HOW CAN WE DEFEND AGAINST THEM? Covid-19 and the Global Predators: We are the Prey Get a copy: https://www.wearetheprey.com/ “No other book so comprehensively covers the details of COVID-19 criminal conduct as well as its origins in a network of global predators seeking wealth and power at the expense of human freedom and prosperity, under cover of false public health policies.” ~ Robert F Kennedy, Jr Author of #1 bestseller The Real Anthony Fauci and Founder, Chairman and Chief Legal Counsel for Children's Health Defense.
Send us Fan MailAmelia Howe is a biomedical engineer and R&D project manager whose career spans startups, research labs, and established medical device companies. She currently leads cross-functional development programs at COLTENE, where she coordinates teams across engineering, quality, regulatory, and manufacturing to bring new medical devices from concept to international launch.Amelia's journey into engineering began with a pivotal shift early in her academic career. While studying at The University of Akron, she transitioned from nursing to biomedical engineering after discovering the field through biomechanics research. Working in Dr. Brian Davis's lab, she contributed to innovative research on shear forces and biomechanics, helping analyze how human movement affects pressure and stress on the body.After graduating summa cum laude, Amelia joined Neuronoff, Inc. as its first employee. In the fast-moving startup environment, she wore nearly every hat imaginable—conducting research, developing prototypes, establishing quality systems, and contributing to core patents. She played a key role in the early development of the Injectrode neuromodulation technology while helping build the company's quality management system toward ISO 13485 compliance.Over time, Amelia gravitated toward project leadership, recognizing that even highly talented engineers need structured coordination to ensure complex products make it through development. She moved into project management roles, overseeing multiple technical programs simultaneously and aligning engineering, regulatory, and business teams around clear timelines and milestones.Today, in addition to her role at COLTENE, Amelia is launching Chrysalis Business Consulting, where she provides project management and business development support to medical device startups. With both an engineering background and an MBA from Quantic School of Business and Technology, she brings a rare perspective that blends technical depth with strategic business insight. LINKS:Amelia Howe LinkedIn: https://www.linkedin.com/in/ameliaehowe/Company website: https://www.linkedin.com/company/chrysalis-business-consulting-llc/Aaron Moncur, host Subscribe to the show to get notified so you don't miss new episodes every Friday.The Being An Engineer podcast is brought to you by Pipeline Design & Engineering. Pipeline partners with medical & other device engineering teams who need turnkey equipment like cycle test machines, custom test fixtures, automation equipment, assembly jigs, inspection stations and more. You can find us at www.teampipeline.usWatch the show on YouTube: www.youtube.com/@TeamPipelineus
Despite a rising demand for services, slower revenue growth and uncertainty in support from the state and federal government, County Manager Mike Bryant's proposed budget for FY 2026-2027 calls for no reduction to services, no property tax increases and strategic new investments. He joins us to discuss how he came up with it.
Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3552: Jackie Beck breaks down how balance transfers can help reduce high-interest debt and potentially accelerate your payoff timeline when used wisely. She highlights both the benefits of low or 0% introductory rates and the hidden pitfalls that can derail progress if you're not careful. Understanding the strategy and its risks can help you decide whether it fits into a smarter, more disciplined approach to getting out of debt. Read along with the original article(s) here: https://www.jackiebeck.com/what-are-balance-transfers/ Quotes to ponder: "Balance transfers are a type of offer from credit card companies, banks, or credit unions. They let you move debt from one account to another." "The idea behind doing a balance transfer is to reduce the interest rate you're paying on credit card debt." "They can be used as part of a larger debt reduction strategy, but shouldn't be the only tool you use." Learn more about your ad choices. Visit megaphone.fm/adchoices
Feeling tired but wired, struggling with sleep, or constantly craving sugar and caffeine? In this Ask a Nutritionist episode of Dishing Up Nutrition, learn how cortisol, the body's primary stress hormone, affects energy, mood, blood sugar, weight, and sleep. Discover practical, natural strategies to help regulate cortisol, including balanced meals, blood sugar support, sleep habits, movement, stress-reducing nutrients, and key supplements such as magnesium and omega-3s, and walk away with realistic tools to help your body feel calmer, more energized, and better equipped to handle daily stress.
If you've been lifting for years and your gains have stalled, there's a hack that recreates the rapid strength gains you had as a beginner, and it works even 15 years into your training career. Sal, Adam, and Justin break down the neuroscience behind newbie gains, share the specific exercises that unlocked a whole new level of growth for each of them, and explain the most common mistake lifters make when trying to apply this (using the new exercise as an accessory instead of making it the priority). Then: a 45% acne reduction from red light therapy in 4 weeks, a chimp civil war in Uganda involving 200 animals that scientists say only happens every 500 years, planned obsolescence in phones and appliances, how Element changed the entire narrative around sodium, and four Instagram Q&As on training while pregnant, switching phases, AI workout programs, and hip imbalances. Sponsors
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