Podcasts about Malignancy

In this episode, host Jonathan Sackier is joined by Andrew Dunbar, Assistant Professor in the Department of Hematopoietic Biology and Malignancy at the University of Texas MD Anderson Cancer Center, Houston, USA. Dunbar discusses his research into myeloproliferative neoplasms, what drives disease progression and resistance, and promising targets for treatment, while reflecting on the mission of his lab and what lies ahead for the field.  Timestamps  00:00 – Introduction  02:29 – One thing people should know about myeloproliferative neoplasms  05:01 – Dunbar's background and research focus  08:00 – What would Dunbar do if not science and medicine?  10:24 – The basics of myeloproliferative neoplasms  14:30 – Myeloproliferative neoplasm diagnosis and treatment  16:49 – What drives disease progression and resistance?  18:30 – The mission of Dunbar's lab  21:23 – Development of AJ1-11095  22:54 – Balancing the complexity of disease modelling with urgent clinical needs  24:03 – Promising targets and pathways  26:35 – What's on the horizon?  28:40 – Three wishes 

Agnes Arnold-Forster's book The Cancer Problem: Malignancy in Nineteenth-Century Britain (Oxford UP, 2021) offers the first medical, cultural, and social history of cancer in nineteenth-century Britain. It begins by looking at a community of doctors and patients who lived and worked in the streets surrounding the Middlesex Hospital in London. It follows in their footsteps as they walked the labyrinthine lanes and passages that branched off Tottenham Court Road; then, through seven chapters, its focus expands to successively include the rivers, lakes, and forests of England, the mountains, poverty, and hunger of the four nations of the British Isles, the reluctant and resistant inhabitants of the British Empire, and the networks of scientists and doctors spread across Europe and North America. The Cancer Problem argues that it was in the nineteenth century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present. Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego and a licensed acupuncturist. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/british-studies

Agnes Arnold-Forster's book The Cancer Problem: Malignancy in Nineteenth-Century Britain (Oxford UP, 2021) offers the first medical, cultural, and social history of cancer in nineteenth-century Britain. It begins by looking at a community of doctors and patients who lived and worked in the streets surrounding the Middlesex Hospital in London. It follows in their footsteps as they walked the labyrinthine lanes and passages that branched off Tottenham Court Road; then, through seven chapters, its focus expands to successively include the rivers, lakes, and forests of England, the mountains, poverty, and hunger of the four nations of the British Isles, the reluctant and resistant inhabitants of the British Empire, and the networks of scientists and doctors spread across Europe and North America. The Cancer Problem argues that it was in the nineteenth century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present. Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego and a licensed acupuncturist. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Agnes Arnold-Forster's book The Cancer Problem: Malignancy in Nineteenth-Century Britain (Oxford UP, 2021) offers the first medical, cultural, and social history of cancer in nineteenth-century Britain. It begins by looking at a community of doctors and patients who lived and worked in the streets surrounding the Middlesex Hospital in London. It follows in their footsteps as they walked the labyrinthine lanes and passages that branched off Tottenham Court Road; then, through seven chapters, its focus expands to successively include the rivers, lakes, and forests of England, the mountains, poverty, and hunger of the four nations of the British Isles, the reluctant and resistant inhabitants of the British Empire, and the networks of scientists and doctors spread across Europe and North America. The Cancer Problem argues that it was in the nineteenth century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present. Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego and a licensed acupuncturist. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/european-studies

Agnes Arnold-Forster's book The Cancer Problem: Malignancy in Nineteenth-Century Britain (Oxford UP, 2021) offers the first medical, cultural, and social history of cancer in nineteenth-century Britain. It begins by looking at a community of doctors and patients who lived and worked in the streets surrounding the Middlesex Hospital in London. It follows in their footsteps as they walked the labyrinthine lanes and passages that branched off Tottenham Court Road; then, through seven chapters, its focus expands to successively include the rivers, lakes, and forests of England, the mountains, poverty, and hunger of the four nations of the British Isles, the reluctant and resistant inhabitants of the British Empire, and the networks of scientists and doctors spread across Europe and North America. The Cancer Problem argues that it was in the nineteenth century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present. Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego and a licensed acupuncturist. Learn more about your ad choices. Visit megaphone.fm/adchoices

Agnes Arnold-Forster's book The Cancer Problem: Malignancy in Nineteenth-Century Britain (Oxford UP, 2021) offers the first medical, cultural, and social history of cancer in nineteenth-century Britain. It begins by looking at a community of doctors and patients who lived and worked in the streets surrounding the Middlesex Hospital in London. It follows in their footsteps as they walked the labyrinthine lanes and passages that branched off Tottenham Court Road; then, through seven chapters, its focus expands to successively include the rivers, lakes, and forests of England, the mountains, poverty, and hunger of the four nations of the British Isles, the reluctant and resistant inhabitants of the British Empire, and the networks of scientists and doctors spread across Europe and North America. The Cancer Problem argues that it was in the nineteenth century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present. Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego and a licensed acupuncturist. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science-technology-and-society

Agnes Arnold-Forster's book The Cancer Problem: Malignancy in Nineteenth-Century Britain (Oxford UP, 2021) offers the first medical, cultural, and social history of cancer in nineteenth-century Britain. It begins by looking at a community of doctors and patients who lived and worked in the streets surrounding the Middlesex Hospital in London. It follows in their footsteps as they walked the labyrinthine lanes and passages that branched off Tottenham Court Road; then, through seven chapters, its focus expands to successively include the rivers, lakes, and forests of England, the mountains, poverty, and hunger of the four nations of the British Isles, the reluctant and resistant inhabitants of the British Empire, and the networks of scientists and doctors spread across Europe and North America. The Cancer Problem argues that it was in the nineteenth century that cancer acquired the unique emotional, symbolic, and politicized status it maintains today. Through an interrogation of the construction, deployment, and emotional consequences of the disease's incurability, this book reframes our conceptualization of the relationship between medicine and modern life and reshapes our understanding of chronic and incurable maladies, both past and present. Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego and a licensed acupuncturist.

The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40694]

The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40694]

The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40694]

The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40694]

The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40694]

The rate of cancer and cancer malignancy differ greatly among mammalian species. The placental – maternal interface is also highly variable between placental mammals. This lecture will discuss recent advances that suggest that there is a causal connection between the evolution of placental biology and the biology and rate of cancer malignancy. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 40694]

Drs Sara Horst and Jordan Axelrad Discuss Risks of Malignancy, Infection With IBD Therapies by Gastroenterology Learning Network

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Join Professor Iain McInnes for the latest episode on The Immune-Mediated Inflammatory Disease Forum, where he discusses the latest updates in RA. In this episode, he discusses two papers: risk of MACE, VTE, and malignancies in patients with RA or UC treated with filgotinib and frequency of reporting of MACE, MI, and stroke between JAKis and anti-TNFα.

Editor-in-Chief Cecelia E. Schmalbach, MD, MSc, is joined by senior author David Goldenberg, MD, to discuss role of estrogen in developing thyroid malignancy as outlined in the paper “Elevated Risk of Thyroid Malignancy in Biological Males Taking Estrogen Hormone Therapy” which published in the April 2025 issue of Otolaryngology–Head and Neck Surgery. They talk about the risk of thyroid cancer for biological males taking estrogen compared to men not undergoing hormone therapy and women.   Click here to read the full article.

Dr. Lauren Parks Nicola, Chief Medical Officer at RevealDx, has extensive experience dealing with the challenges of accurately describing lung nodules and distinguishing between benign and malignant nodules based on visual inspection of CT scans. RevealDx software tool integrates into the radiologists' workflow and uses advanced algorithms and a large database of lung nodule data to provide a malignancy score for lung nodules. This technology can help reduce unnecessary follow-up scans and invasive procedures for patients with benign lung nodules while identifying high-risk ones requiring more aggressive investigation. Lauren explains, "Reveal's product is a software that characterizes lung nodules. So lung nodules, little blips on a lung that we find on a chest CT. And the thing is, they're very, very common. Lots of patients have them, they can turn out to be cancer, most of them aren't. But with the knowledge that we have right now, just as radiologists looking at those nodules, it's really hard to tell which ones are going to turn out to be cancerous and which ones aren't."  "The software tool characterizes which nodules are more likely to be malignant and might need faster diagnosis, more aggressive workup, biopsy, some interventions, things that can help us diagnose cancer earlier when it's easier, less expensive, and much better for the patient to treat versus the ones that don't need that kind of care. And for a lot of patients, that means not needing follow-up scans, not needing biopsies, and not needing invasive treatments to prevent something that would never have been a problem for them in the first place. So it is that added information, as well as added clinical information, gives us and the patients tools to better predict how these are going to behave." #RevealDx #RadiologyAI #MedicalImaging #Radiology #LungCancer #DigitalHealth #ArtificialIntelligence #AI #AIinHealthcare #MedicalAI  reveal-dx.com Download the transcript here

Dr. Lauren Parks Nicola, Chief Medical Officer at RevealDx, has extensive experience dealing with the challenges of accurately describing lung nodules and distinguishing between benign and malignant nodules based on visual inspection of CT scans. RevealDx software tool integrates into the radiologists' workflow and uses advanced algorithms and a large database of lung nodule data to provide a malignancy score for lung nodules. This technology can help reduce unnecessary follow-up scans and invasive procedures for patients with benign lung nodules while identifying high-risk ones requiring more aggressive investigation. Lauren explains, "Reveal's product is a software that characterizes lung nodules. So lung nodules, little blips on a lung that we find on a chest CT. And the thing is, they're very, very common. Lots of patients have them, they can turn out to be cancer, most of them aren't. But with the knowledge that we have right now, just as radiologists looking at those nodules, it's really hard to tell which ones are going to turn out to be cancerous and which ones aren't."  "The software tool characterizes which nodules are more likely to be malignant and might need faster diagnosis, more aggressive workup, biopsy, some interventions, things that can help us diagnose cancer earlier when it's easier, less expensive, and much better for the patient to treat versus the ones that don't need that kind of care. And for a lot of patients, that means not needing follow-up scans, not needing biopsies, and not needing invasive treatments to prevent something that would never have been a problem for them in the first place. So it is that added information, as well as added clinical information, gives us and the patients tools to better predict how these are going to behave." #RevealDx #RadiologyAI #MedicalImaging #Radiology #LungCancer #DigitalHealth #ArtificialIntelligence #AI #AIinHealthcare #MedicalAI  reveal-dx.com Listen to the podcast here

Sin is like cancer. Our whole nature is permeated by sin. In certain places it looks to be dormant but in other areas is causing destruction. Sin that is left unhindered will eventually impact the whole of a person and has the ability to infect other people.

Speaker: Adam GodshallSeries: "Respectable Sins" and SanctificationText: James 1; Numbers 13-14Theme: The Malignancy of Sin

In this interview Xander is joined by the guys in Malignancy before their show at The Brass Mug in Tampa! Excerpts from the Malignancy track "Existential Dread" (2024) used with permission from the artist. Check out Malignancy's music at https://www.youtube.com/@MalignancyNY Purchase music and merchandise from Malignancy at https://malignancy.bandcamp.com/music SOCIAL LINKS: Twitter: https://twitter.com/metaldebate/ Facebook: https://www.facebook.com/thegreatmetaldebate/ Instagram: https://www.instagram.com/metaldebate/ The Great Metal Debate Podcast: https://podcasts.apple.com/us/podcast/the-great-metal-debate-podcast/id1037874814 https://soundcloud.com/thegreatmetaldebate CONTACT Business email: TheGreatMetalDebate@gmail.com

Full article: Bosniak Classification of Cystic Renal Masses Version 2019: Proportion of Malignancy by Class and Subclass—Systematic Review and Meta-Analysis Aric Berning, MD, discusses the AJR article by McGrath et al. that provides a meta-analysis of malignancy proportions for Bosniak classification version 2019, stratified by class and subclass.

Commentary by Dr. Lorenzo Gervaso

In this episode of Rash Decisions, hosts Dr George Moncrieff and Dr Roger Henderson delve into actinic keratoses (AKs), also known as solar keratoses. With expert insights, they discuss the nature of these common sun-induced lesions, their role as markers of both UV exposure and damage, along with practical approaches to diagnosis.  Key Takeaways:  How to differentiate AKs from other keratotic lesions, including Bowen's disease, keratoacanthoma and squamous cell carcinoma (SCC) The significance of clinical grading and the concept of "field cancerization" Practical tips for dermatoscopic evaluation and deciding when to refer patients.  Tune in to enhance your understanding of AKs and how the majority can be managed within primary care settings.  Thank you to our kind sponsor AproDerm, who provide a comprehensive range of quality emollients designed for the management of dry skin conditions, including eczema, psoriasis and ichthyosis.   To simplify the process of finding the most suitable emollient for each patient, they have developed a remarkable solution: the AproDerm Emollient Starter Pack. This pack conveniently combines all four of their emollients in a single prescription, enabling patients to identify their ideal emollient more efficiently, aiding both compliance and adherence.   Find out more: https://aproderm.com/aproderm-emollient-starter-pack/    LI: https://www.linkedin.com/company/fontus-health-ltd/   IG: https://www.instagram.com/aproderm/  Got some feedback for us? Please rate and review Rash Decisions to help us keep creating educational podcasts for you.   Is there a dermatology topic you'd like us to explore? Email us at info@aproderm.com, and we'll do our best to cover it.  The views expressed in this podcast are of Dr George Moncrieff and Dr Roger Henderson. Fontus Health has not influenced, participated, or been involved in the programme, materials, or delivery of educational content. 

Host: Darryl S. Chutka, M.D. Guest: Aaron M. Potretzke, M.D. Today, we're airing a popular episode from Season 2 of Mayo Clinic Talks!  Happy Holidays! Microscopic hematuria, and less commonly gross hematuria, are conditions commonly seen by the primary care provider. Malignancy is the most ominous cause of hematuria. Fortunately, other causes are much more likely. Since this is a relatively common health condition, when should we investigate hematuria and what should the evaluation consist of? How do we evaluate a patient's risk for urinary tract malignancy? Dr. Aaron Potretzke, a urologist at Mayo Clinic, joins us to discuss these questions. Connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

IBD Drive Time: Jordan Axelrad, MD, on Treating Patients With IBD and Malignancy by Gastroenterology Learning Network

Rheumatologists Dr. Jeffrey Curtis and Dr. Jon Giles discuss the risk of comorbidities that can occur as a consequence of uncontrolled inflammation in RA

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Epistemic states as a potential benign prior, published by Tamsin Leake on August 31, 2024 on The AI Alignment Forum. Malignancy in the prior seems like a strong crux of the goal-design part of alignment to me. Whether your prior is going to be used to model: processes in the multiverse containing a specific "beacon" bitstring, processes in the multiverse containing the AI, processes which would output all of my blog, so I can make it output more for me, processes which match an AI chatbot's hypotheses about what it's talking with, then you have to sample hypotheses from somewhere; and typically, we want to use either solomonoff induction or time-penalized versions of it such as levin search (penalized by log of runtime) or what QACI uses (penalized by runtime, but with quantum computation available in some cases), or the implicit prior of neural networks (large sequences of multiplying by a matrix, adding a vector, and ReLU, often with a penalty related to how many non-zero weights are used). And the solomonoff prior is famously malign. (Alternatively, you could have knightian uncertainty about parts of your prior that aren't nailed down enough, and then do maximin over your knightian uncertainty (like in infra-bayesianism), but then you're not guaranteed that your AI gets anywhere at all; its knightian uncertainty might remain so immense that the AI keeps picking the null action all the time because some of its knightian hypotheses still say that anything else is a bad idea. Note: I might be greatly misunderstanding knightian uncertainty!) (It does seem plausible that doing geometric expectation over hypotheses in the prior helps "smooth things over" in some way, but I don't think this particularly removes the weight of malign hypotheses in the prior? It just allocates their steering power in a different way, which might make things less bad, but it sounds difficult to quantify.) It does feel to me like we do want a prior for the AI to do expected value calculations over, either for prediction or for utility maximization (or quantilization or whatever). One helpful aspect of prior-distribution-design is that, in many cases, I don't think the prior needs to contain the true hypothesis. For example, if the problem that we're using a prior for is to model processes which match an AI chatbot's hypotheses about what it's talking with then we don't need the AI's prior to contain a process which behaves just like the human user it's interacting with; rather, we just need the AI's prior to contain a hypothesis which: is accurate enough to match observations. is accurate enough to capture the fact that the user (if we pick a good user) implements the kind of decision theory that lets us rely on them pointing back to the actual real physical user when they get empowered - i.e. in CEV(user-hypothesis), user-hypothesis builds and then runs CEV(physical-user), because that's what the user would do in such a situation. Let's call this second criterion "cooperating back to the real user". So we need a prior which: Has at least some mass on hypotheses which correspond to observations cooperate back to the real user and can eventually be found by the AI, given enough evidence (enough chatting with the user) Call this the "aligned hypothesis". Before it narrows down hypothesis space to mostly just aligned hypotheses, doesn't give enough weight to demonic hypothesis which output whichever predictions cause the AI to brainhack its physical user, or escape using rowhammer-type hardware vulnerabilities, or other failures like that. Formalizing the chatbot model First, I'll formalize this chatbot model. Let's say we have a magical inner-aligned "soft" math-oracle: Which, given a "scoring" mathematical function from a non-empty set a to real numbers (not necessarily one that is tractably ...

IBD Drive Time: Jordan Axelrad, MD, on IBD and Malignancy by Gastroenterology Learning Network

Canadian legends Rush are obviously huge around the RAM offices. And our own Aaron is a badass bassist as well. So of course we both got sucked right into the Paramount + mini series "Geddy Lee Asks 'Are Bass Players People Too' ". The bassist extraordinaire spends time with four major music movers and shakers that strum the four strings. The program sent our imaginations into overdrive. This week we fantasy book our own Season Two. Our picks range from some all time greats to underground underdogs to Lemmy (??!!). In our "News, Views and Tunes", we discuss Gojira at The Olympics. Musically, we crank some Ironflame, Tokyo Blade, Poison Idea, Malignancy, Helms Deep, Warlust and introduce Florida trad metallers Living Fast in our "Indie Spotlight". Horns Up!

Ep. 189 - Malignancy by Cali Death Podcast

To abruptly switch gears from our Very Special Episode earlier this week, we deliver reviews of the newest installments from two tech death giants. Ulcerate is back with their seventh full-length record which shows the band committing even more fully to the elements of post-rock, black metal, and textured drone which have helped define their sound- but have they strayed too far from the path? Pitted against them is the mutated monstrosity Malignancy's fourth full-length, which seeks to bring their sound a bit closer to the center of death metal while leaving their whiplashing, wild style of technicality intact- but can they maintain their vicious edge? YOU WOULD LIKE TO KNOW MORE. 0:00:00 - Intro 0:01:56 - Ulcerate - Cutting the Throat of God (Debemur Morti Productions) 0:54:35 - Interlude - The Brass - “Treading Water,” fr. the Rugged Cross EP (Independent, 2015) 0:58:44 - Malignancy - …Discontinued (Willowtip Records) 1:40:43 - Outro - Copremesis - “A Poem” fr. Muay Thai Ladyboys (Paragon Records, 2008) Terminus links: Terminus on Youtube Terminus on Patreon Terminus on Instagram Terminus on Facebook thetrueterminus@gmail.com

Welcome back to The Great Metal Debate podcast. Today we are talking about the fourth full-length studio album by the New York brutal tech death band Malignancy titled ...Discontinued, which was dropped on June 14th through Willowtip Records. This is the band's first album in 12 years so this certainly calls for celebration. For a band that has been around since 1992, you would think that they would have much more albums in their discography but, I guess some bands like to really take the time with their craft. Before diving into this new record track by track, I'm going point out a major similarity that I've always noticed about this band. Particularly with the vocalist Danny Nelson having a nearly identical sounding voice to Ross Dolan from Immolation. I had often wondered if Malignancy was a side project band, which would make a lot of sense seeing as how both bands are from Yonkers! The answer is no, Danny and Ross are two different people. However, Danny had done vocals for Mortal Decay's 2013 album The Blueprint For Blood Spatter. When I looked up the names of the band members, I had to do a double take when I saw the bass player. At first I thought it said Alex Webster from Cannibal Corpse, but nope, the new bass player is Alex Weber. Haha, not Webster. Coincidentally enough, guess where Cannibal Corpse originally started. You guessed it, New York. Except they formed in Buffalo. According to Metal-Archives, Alex Weber has played live for Defeated Sanity and Obscura. Guitarist Ron Kachnic has also been in Pyrexia, Demolition Hammer and Mortician! Mike Heller has been the drummer for multiple bands including System Divide which is Sven from Aborted's side project band. Despite not advertising as such, Malignancy IS a super group. Kicking things off we have the first track titled "Existential Dread". As you listen to this album, you can feel Danny's lips press against the microphone as he delivers his powerful vocals. You can tell he definitely uses his diaphragm to produce such a monstrous tone. Watch a few live videos of them and you can witness for yourself Danny's commanding stage presence too. "Purity of Purpose" was the first single released for this album about 2 months beforehand. I remembered as soon as I heard it, I immediately looked up the full-length release date and album title just to add it to my list. Judging from that track alone, I knew I had to review it. The second single "Biological Absurdity" was uploaded a month later and it of course blew me away. Both of these songs were aired on YouTube as official tracks but we haven't been treated to a music video yet. I have found myself jamming this album front to back since its release a little over a week ago and I gotta say, I'm impressed! I mean, Malignancy never disappoints. This album is absolutely killer and one of the finest examples of your standard death metal. Bad ass death metal albums without an overly unique pizazz quality about them are still more than capable of getting a good rating out of me. This is definitely one of the better straight forward death metal albums I've heard in 2024 so far. With that being said, I'm feeling a nice 8/10 rating. Malignancy has been kickin around in the underground scene since I was a 1-year-old. They've gone through a few line-up changes here and there but have held strong as a band for the past three decades. Their popularity may not be up on the same level as many other bands but they deserve a lot of credit, respect and most of all support. You can buy their merch ... at pretty much any online metal merch outlet. The most obvious choice would be bandcamp, but they also have merch at primitiverecordings.com, hellsheadbangers.com and indiemerch.com. Of course, if you get lucky enough to see them live; they definitely have a merch table and I hear that they are usually at their stand before and after a show. So don't be shy, go say hi and if nothing else, throw them a few bucks in their tip jar.

On this week's episode, Jon and Brandon discuss new releases from Charli XCX, Peggy Gou, KAYTRANADA, RM, NxWorries, The Early November, Malignancy, Vomit the Soul, Swelling Repulsion and more!   Intro Music by Anthony Reeder   Show Notes: Link To Weekly Rotating Playlist: https://open.spotify.com/show/6EE5pohSvSjm5ZFQf45iv1?si=32cab828e94d4a24

S10E260: Soundtrack for the Eclipse Lessons people wish they learned sooner, bizarre celebrity facts, sex stories, eclipse beliefs, did you know facts, a death row conversation, and heavy metal for your filthy earballs! (00:00:00) - Intro (00:00:57) - Malignancy, SONG: Purity of Purpose (00:04:46) - Deal with God, SONG: Imposter (00:07:06) - Conversation 1 (00:15:31) - Black Wound, SONG: Trench Blast (00:20:00) - Pantheon Omega, SONG: Invokation to War (00:24:42) - Conversation 2 (00:32:32) - Helms Deep, SONG: Serpent's Eye (00:36:17) - Abreaktion, SONG: Broken Promises (00:40:25) - Tusenårseken, SONG:Fattigdomens Köttkvarn (00:46:16) - Conversation 3 (00:52:56) - Grandma's Pantry: Abstrakt Algebra, SONG: Stigmata (00:58:28) - Conversation 4 (01:08:42) - GRAVKVADE, SONG: En Himlakropps Dödsbädd (01:17:06) - ARISTARCHOS, SONG: Oath: Dispersal of the Spectral Awning in Perpetual Flame (01:21:16) - Diabolic Oath, SONG: Rusted Madness Tethering Misbegotten Haruspices Labels: Willowtip Records, Chaos Records, Nameless Grave Records, Transylvanian Recordings, Vendetta Records, Sentient Ruin Laboratories

Episode One, Part Two of the “Real World LDRT” miniseries (sponsored by Xstrahl) circles back to the 1940s and the extraordinary flaws of the "linear no threshold" (LNT) model of radiation risk. We explore backroom deals, handshake science, corporate greed, regulatory capture, hormesis, OSHA violations, putting radium in the throats of 2.5 million children...you know, the regular, everyday stuff. Why? Because a common hesitation to deploying LDRT for arthritis is the risk of the treatment itself causing cancer. Spoiler alert: there has never been a case of secondary malignancy from therapeutic radiation below a magical threshold dose. And LDRT stays below that threshold. Don't believe me? That's why this miniseries exists! Relevant papers and sources at ⁠http://u.pc.cd/OhN⁠ Brought to you in part by Xstrahl, modern manufacturers of orthovoltage devices. Visit them at ⁠https://xstrahl.com/⁠ OOTB, produced by Photon Media, is made possible by Cold Light Legacy, a 501(c)(3) nonprofit that thrives on community support. jason@coldlight.org --- Support this podcast: https://podcasters.spotify.com/pod/show/radmed/support

Dr. Erica Golemis is a Professor, Deputy Chief Science Officer, Co-Leader of the Molecular Therapeutics Program, and Director of the High Throughput Facility at the Fox Chase Cancer Center in Philadelphia. In addition, Erica is an adjunct faculty member at the University of Pennsylvania, Drexel University School of Medicine, and the Temple University Lewis Katz School of Medicine. For most of her scientific career, Erica has been conducting cancer research. Her recent work investigates why some cancers are particularly malignant. Erica's research examines what genes cause cancer to change and progress, whether there are genes that can be targeted directly with different treatments to reverse this process, and if there is a therapeutic time window in which they could potentially reverse this process. When Erica finds free time, one thing she loves to do is read. She reads broadly and has been an avid reader since her early childhood. Erica also has fun attending theatre performances. There are multiple excellent theaters in her home city of Philadelphia, and she especially enjoys shows by British playwright Tom Stoppard. She completed her undergraduate studies in biology and English at Bryn Mawr College and was awarded her PhD in biology from the Massachusetts Institute of Technology. Afterwards, Erica conducted postdoctoral research at the Massachusetts General Hospital Department of Molecular Biology and Harvard Medical School department of Genetics before joining the Fox Chase Cancer Center. In this interview, Erica speaks about her experiences in both life and science.

In this week's episode we'll discuss the findings from a prospective trial of TCRαβ/CD19-cell depleted HLA-haploidentical transplantation to treat pediatric acute leukemia, learn more about the incidence, clinical characteristics, and survival of malignancy-associated hemophagocytic lymphohistiocytosis in Sweden, and discuss the bone marrow as the primary site of thrombopoiesis. 

In this week's episode we'll discuss the findings from a natural history study of patients with familial platelet disorder with myeloid malignancy, learn more about the role of HEXIM1 as an essential transcription regulator in human erythropoiesis, and discuss the utility of residual disease as a predictor of relapse in CML patients stopping TKI therapy.

Pink Sheet reporter and editors discuss the FDA acknowledging reports of malignancies in patients who received CAR-T cell immunotherapies (:35), the agency's policy for using background music in direct-to-consumer advertising (7:27), and the FDA's new incoming principal deputy commissioner (13:44). More On These Topics From The Pink Sheet CAR-T Malignancy Reports Could Temper Excitement For Use Beyond Oncology: https://pink.citeline.com/PS149420/CAR-T-Malignancy-Reports-Could-Temper-Excitement-For-Use-Beyond-Oncology Background Music During Risk Segment Of Rx Drug Ads: FDA Explains Its Policy: https://pink.citeline.com/PS149411/Background-Music-During-Risk-Segment-Of-Rx-Drug-Ads-FDA-Explains-Its-Policy US FDA Chief Scientist Bumpus Will Become Principal Deputy Commissioner: https://pink.citeline.com/PS149428/US-FDA-Chief-Scientist-Bumpus-Will-Become-Principal-Deputy-Commissioner

Full article: https://www.ajronline.org/doi/10.2214/AJR.23.29826  Hong Linda Li, MD discusses a new article that examines the need for a comprehensive approach that integrates clinical, radiological, and histopathological data for accurate diagnosis and management of adrenal masses.

Have you ever wondered about how to treat VTE in malignancy? This episode goes over all the ins and outs of this complex and nuanced topic! Written by Dr. Kevin Yijun Fan, Internal Medicine and reviewed by Dr. Helena Dhamko, (Hematology) and Dr. Ed Etchells (General Internal Medicine).  Infographic by Valarie Kim (Internal Medicine Resident). Support the show

Radiation oncology in GI malignancy (endpoints and stratification) in the JCO

Sam talks with writer and historian Paul Street (also on the RefuseFascism.org Editorial Board) about recent events including the fascist attempts to shut down the government, the ouster of Kevin McCarthy from the Speaker of the House, and the increasingly violent threats and promises of vengeance from current frontline candidate for president and as-yet unconvicted coup plotter Donald Trump. Follow Paul on his Substack and read his latest article, Nether the Fascist Trump Nor Imperialist Biden Mentioned in this episode: America needs to talk about the right's ‘Red Caesar' plan for U.S. dictatorship by Will Bunch Trump's Bloody Campaign Promises by David Remnick Related episodes: Fascism In America: Past and Present Trump Indicted and Media Complicity in the Rise of Fascism The Fantasy of the Reasonable Republican  How to help the show? Rate and review wherever you get your podcasts; share with your friends! Get involved at RefuseFascism.org. We're still on Twitter (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@RefuseFascism⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠) and other social platforms including Threads, Mastodon and Bluesky. Send  your comments to samanthagoldman@refusefascism.org or ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@SamBGoldman⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Record ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠a voice message for the show here. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Connect with the movement at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠RefuseFascism.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and support: · ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠paypal.me/refusefascism⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ · ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠donate.refusefascism.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ · ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/refusefascism⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Music for this episode: Penny the Snitch by Ikebe Shakedown --- Send in a voice message: https://podcasters.spotify.com/pod/show/refuse-fascism/message

Dr. Refky Nicola discusses the potential role of contrast-enhanced US in the differentiation of malignant and benign lesions with Dr. Edward Grant.   Contrast-enhanced US to Improve Diagnostic Performance of O-RADS US Risk Stratification System for Malignancy. Yuan et al. Radiology 2023; 308(2):e223003.   Adding Contrast-enhanced US to O-RADS: A Route to Improved Specificity? Grant. Radiology 2023; 308(2):e231483.

Join us as we review recent articles and news featured in The DIGEST #43 and #44, including bempedoic acid to lower cardiovascular risk, Alpha-Gal Syndrome, tick bites and meat allergy, orforglipron an oral GLP1 agonist for weight loss, zuranolone for postpartum depression, DOACs for VTE of malignancy, monoclonal antibodies (mAbs) for Dementia, cytisinicline for smoking cessation, and two kiwis a day for constipation. Fill your brain hole with a delicious stack of hotcakes! Featuring Drs. Paul Williams (@PaulNWilliamz), Nora Taranto (@norataranto), and Matt Watto (@doctorwatto). Claim free CME for this episode at curbsiders.vcuhealth.org! Episodes | Subscribe | Spotify | Swag! |Mailing List | Contact | Free CME! Credits Written and Hosted by: Nora Taranto MD; Paul Williams, MD, FACP, Matthew Watto MD, FACP Cover Art: Matthew Watto MD, FACP Reviewers: Nora Taranto MD; Paul Williams, MD, FACP, Matthew Watto MD, FACP Technical Production: Pod Paste Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Sponsor: Netsuite Download NetSuite's popular KPI Checklist, designed to give you consistently excellent performance for free, at NetSuite.com/CURBSIDERS Sponsor: Locumstory  Get a comprehensive view of locums and decide if it's right for you at locumstory.com. Sponsor: Grammarly  Go to grammarly.com/GO to download for FREE today. Sponsor: Pathway Download the Pathway app today by visiting pathway.md Show Segments Intro, disclaimer Bempedoic Acid for CV risk reduction DOACs to prevent recurrent VTE of malignancy Cytisinicline for smoking cessation Alpha-Gal Syndrome, tick bites, and meat allergy Zuranolone for postpartum depression Orforglipron, an oral GLP1 agonist, for weight management mAbs for Alzheimer's dementia Kiwis to prevent constipation Outro

In this episode I bring to you... "A Case of Malignancy in a Lumbar Spine Pain Patient."1.  Review of a patient scenario with chronic LBP.2.  Identify the specific “red flags” associated with this patient situation.3.  Brief review of lumbar spine “red flags”.4.  Bring some tissues for this one.  This story might tug at your heart a little. Or you may even get angry to hear how it turned out.  Support OEP today!Welcome to our new sponsor!  Chattanooga.  To check out all they have to offer, trial modalities, have your questions answered about shockwave therapy, high level laser, radial pressure wave, connect with them HERE!Want to join the OEP community? Click HERE to jump onto our email list. SUBSCRIBE at the bottom of the page.Ask me your ortho evaluation questions and I will answer them on the show: paul@orthoevalpal.comCome visit our WEBSITE!! Click HERE to check it outGet our downloadable 1.5 hour shoulder anatomy with cadaver dissection lectureGet our downloadable 7.5 hour cervical and lumbar continuing ed courseGet our downloadable 6.0 hour shoulder continuing ed courseBe sure to "follow" us on our new Facebook PageI finally made it to Instagram. Stop by and check us outAre you looking for One on one Coaching? We have it!Be sure to check out our 500+ videos on our YouTube Channel called Ortho Eval Pal with Paul Marquis#lumbarspine #lumbarredflags #podcasts #PTpodcast #medical #health #orthopedics #Physicaltherapy #running #DPT #Medicalproviders #sportsmedicine #athletictraining#chiropracticSupport the show Thanks for listening! If you like our podcast, be sure to check out more of our great content at OrthoEvalPal.com, Instagram and Youtube. We'd love a rating or review on your podcast platform. And, as always, be kind to each other and take care!!