Podcasts about grignard

Amélie reçoit et Katell Bidon, la directrice et Gaétan Grignard, responsable de la communication de La Renaissance, scène vivante de Mondeville, pour parler de la dixième édition du festival À partir du réel. Le festival se tiendra du 12 janvier au 7 février. Avec au programme: des spectacles, des rencontres, des projections, de la littérature et des moments de convivialité. SON DU JOUR: Bright Eyes - Thundermother

Amélie reçoit Gaétan Grignard, responsable de la communication de la Renaissance, ainsi que Katell Bidon, directrice de la Renaissance pour nous parler de La Renaissance et de sa programmation 2024. Au programme également la chronique de Benjamin, “Back To The Classic”. Son du jour: MAMIMAMI - LUIDJI

Dans cette émission on s'intéresse aux "Plateaux éphémères", un festival porté par le théâtre La Renaissance à Mondeville. Pour en parler Elvire est accompagnée de Gaétan Grignard ! Le son du jour : Dust bunny - Crumb

Most of us don't grow up across the street from a chemistry building or know from an early age that we want to be a scientist, but Alan Dyke, VP of Business Development for ProChem, Inc. (CTO of Boulder Scientific Company at the time of the interview) did and became a chemist. Dr. Alan Dyke, former colleague, and friend of Paolo's, shares his career path and discusses the history and current state of the field of catalysis. With a father that taught university-level chemistry, and a brother in the field, it may not be surprising that Alan Dyke became a chemist, but it is surprising is that he's considered to be the outcast of the family for choosing a commercial career instead of taking an academic route. But, as he'll passionately reveal, there are upsides to choosing a non-academic career. Join us for a wonderful conversation where Paolo and Alan recount their shared history and the evolution of the catalysis field over recent decades. They discuss the evolution of homogeneous cross-coupling, biocatalysis, metathesis, and metallocene chemistry. Application of catalysis to fields as varied as pharmaceuticals and polymers is discussed, along with sustainability and other trends and dynamics in the field. Overcome your activation energy and join us!Related episodes: Season 1, Ep.2: Reinventing plastics, one reaction at a time Season 2, Ep.1: Chemistry: a modern American dreamSeason 2, Ep.6: The charm of the forgotten elements Bonus content!Access bonus content curated by this episode's guest by visiting www.thermofisher.com/chemistry-podcast for links to recent publications, podcasts, books, videos and more.View the video of this episode on www.thermofisher.com/chemistry-podcast. A free thank you gift for our listeners! Visit the episode website and request your free Bringing Chemistry to Life t-shirt.Use Podcast Code:  laBcheM in March or sc13nc3 in April We read every email so please share your questions and feedback with us! Email helloBCTL@thermofisher.com About Your HostPaolo Braiuca grew up in the North-East of Italy and holds a PhD in Pharmaceutical Sciences from nearby esteemed University of Trieste, Italy. He developed expertise in biocatalysis during his years of post-doctoral research in Italy and the UK, where he co-founded a startup company. With this new venture, Paolo's career shifted from R&D to business development, taking on roles in commercial, product management, and marketing. He has worked in the specialty chemicals, biotechnology, and pharmaceutical markets in Germany and the UK, where he presently resides. He is currently the Director of Global Market Development in the Laboratory Chemicals Division at Thermo Fisher Scientific™ which put him in the host chair of the Bringing Chemistry to Life podcast. A busy father of four, in what little free time he has, you'll find him inventing electronic devices with the help of his loyal 3D-printer and soldering iron. And if you ask him, he'll call himself a “maker” at heart.

Gaétan Grignard du Théâtre de la Renaissance de Mondeville était dans Label Antenne. Il venait de nous présenter la programmation du  Festival à partir du réel, qui se déroule jusqu'au 27 janvier prochain.  En deuxième partie d'émission, Anna-Lou du Café des Images était dans l'émission pour faire le tour des prochains événements du cinéma d'Hérouville, et Paul était de retour pour sa chronique - de 10 !  Son du jour : 6 de la manana - Jimmy Whoo

Emission spéciale Théâtre avec l'équipe de La Renaissance, scène vivante de Mondeville. Elvire recevait la directrice Katell Bidon, et Gaétan Grignard le responsable de la communication. En deuxième partie d'émission, quelques recommandations de podcasts et autres créations sonores ! Son du jour : Simply Paradise - Mac Demarco

“The goal is to share knowledge through open-sourced tools, and for people to use them as much as possible”In his presentation, Arnaud Grignard shared some of the work he does with his team at the City Science group at the MIT Lab, specifically a tool called City Scope. The common thread for all examples was how this tool made it possible to use data visualisation to analyse patterns and potential outcomes when developing cities. By building physical representations of cities, and projecting data onto the city, it's possible to visualise behaviours on a large scale, such as movements of people and vehicles, and alter them to analyse the effects. One of the shown examples was a project analysing the effects of air-quality on depending on the way people in a city commute, giving a clear visual and physical representation on what it entails to take the car, public transport or bikes.City planning can be quite abstract and complex and open-source tools like City Scope can help make the abstract more concrete. It can contribute to the democratisation of these types of analytics, and can be used as a way to communicate otherwise often overwhelming and complicated  data to new types of shareholders.But the most important thing that was pointed out, was that since this type of modelling is an open-source tool it's available for everyone, at any time. These types of tools are available to us, so we should be using them as much as we possibly could in the planning of our cities.

Dans cette émission, Maxime recevait Gaëtan Grignard, chargé de communication au théâtre La Renaissance, pour parler de la 12ème édition de Plateaux Ephémères, le festival d'arts de rue, qui se tiendra cette année, du 27 au 28 mai 2023. Son du jour : La Femme - Leila

This week on the podcast, I meet Belgian coach Olivier Grignard.In our conversation, Olivier tells me how his tennis story began.Olivier also tells me about his coaching role in china, we discuss some of the cultural differences between juniors in Europe and juniors in Asia, and much much more.Hope you enjoy itFabioCarlos Rodriguez episode: https://www.functionaltennis.com/blogs/the-functional-tennis-podcast/carlos-rodriguez-former-coach-of-justine-henin-li-na-ep-143Have you seen the Functional Tennis Saber?Check it out here and don't miss the video of Stan Wawrinka crushing the ballThis podcast is sponsored by ASICS. ASICS is a Japanese company founded in 1949 with the purpose of giving more people the opportunity to experience how sport and movement can have a positive impact on mental wellbeing.To learn more about ASICS visit their website here: https://www.asics.com/nl/en-nl/sports/tennis/Find us on Social Media:Instagram: Instagram.com/FunctionalTennisYouTube: Functional Tennis PodcastTwitter: twitter.com/functennisWebsite: www.FunctionalTennis.comThis podcast uses the following third-party services for analysis: Chartable - https://chartable.com/privacy

On the show this week, as the NHL forbids players from going to the Beijing Olympics (1:06), Mark and Haig discuss the impact on the Games (2:08), why Olympic hockey is important (3:38), who will replace the NHL players (4:41), and dig into the NHL's decision — and its timing (5:45). Elsewhere, a look at how the NHL decision benefits the Chinese team (6:33), which has had some roster upheaval – and friction — in recent days (7:54). Mark also talks about his media tour – talking about Peng Shuai with NBC, WTA with Reuters (10:00), and women's hockey — and tennis! — with CGTN (12:04). Plus, all the latest in the Peng Shuai Exhibition Tour, as she is paraded in Shanghai (12:52).Next, we talk to Olivier Grignard, a Belgian tennis coach who first came to China in 2011 to work alongside Li Na's coach Carlos Rodriguez, and has seen a lot of change over the subsequent years (14:31). He's currently working with Chinese tennis player Lu Jiajing (highest world ranking 162) — who also came into the studio! – and is running his own NextChamp program (15:50). He talks about the impact that Li Na has had on the sport in China (17:23), gives his verdict on China's rising stars Wang Xinyu and Wang Xinyu (18:22), outlines the typical setup of China's top players (20:14), and explains why the best juniors don't always find success at the pro level (20:45). Next, Grignard compares Chinese players with their international counterparts (22:29), explains why the Chinese men haven't had the same success as the women (23:42), reveals where the good players are coming from (25:54), and discusses the difference between state support for Chinese players versus those who hire their own team (27:02).Finally, Grignard discusses the impact on player development given the suspension of WTA tournaments in China and the fact that Chinese players can't easily travel overseas (28:20), before revealing his plans for the future alongside Lu Jiajing (29:49).See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Isaiah Speight (he/him) is currently a NIGMS postdoctoral fellow at University of California, Irvine in the lab of Prof. Vy Dong. His postdoctoral work focuses on developing new technologies to enhance peptide synthesis. As a native of the Hampton-Roads area of Virginia, Isaiah earned his B.S. in chemistry in 2016 from Norfolk State University. During this time, he did research with Prof. Olufemi Oyesanya in the area of polymer synthesis, and with Prof. Steven Townsend in advanced carbohydrate synthesis. Isaiah then moved to Nashville, where he completed his Ph.D. in 2021 from Vanderbilt University with Prof. Timothy Hanusa. During his time as a Ph.D. student Isaiah developed new mechanochemical methods for making inorganic and organometallic reagents ranging from calcium complexes and mercury metal organic frameworks to Grignard reagents from fluorinated compounds. In addition to his bench work, Isaiah works very closely with the National Organization for Black Chemists and Chemical Engineers initially serving on the Executive Board as their National Student Representative and currently as their Western Regional Director. In these roles, Isaiah works to continue to create communities for black scientists to thrive in as well as build connections to create new opportunities for these students to be successful in. You can follow Dr. Speight on twitter @IR_SP8. Link to NOBCChE's website Dr. Speight's Favorites 1.) Favorite Comfort Food: A good burger 2.) Song to get you hyped: "Super" by Cordae 3.) What's on Dr. Speight's watchlist? Restart the new season of Haikyuu, season 2 of Demon Slayer, Hawkeye as the episodes release. 4.) Favorite Spiderman movie moment? Into the Spider-Verse when Miles finally grows into himself and “what's up danger” starts playing! ---- Chemistea is a chemistry and science podcast founded by Lucy Yang (she/her), currently a fourth-year undergraduate at UC Irvine, studying chemistry and biological sciences. Some of the most famous scientific collaborations and discoveries were born from a conversation over tea, and on her podcast, Lucy aims to combine her love of talking with her love of sharing and hearing stories—stories about others' passion for science, their journeys, and any and all fun shenanigans in between. You can follow Lucy on twitter @isolucyine. She is also the founder of The Kawaii Chemist, a shop where you can find cute chemistry stickers and merch, where 100% of profit goes to charity. You can check out The Kawaii Chemist here, and you can donate to support Kawaii Chemist and the Chemistea podcast here. Thank you listening!

Félicity saison 2, me revoilà!  Avec des interviews incroyables en préparation sur des sujets de prospective - parce que le thème de comment vivra- t- on en ville demain et comment s'y préparer me passionne -, et un focus données aussi, parce qu'il y a là un levier évident et immense pour des solutions nouvelles.  Et justement aujourd'hui on va parler de données, avec Arnaud Grignard, chercheur affilié au MIT.  J'ai eu l'occasion cette année de suivre une formation, passionnante d'ailleurs, au MIT Media Lab intitulée "Beyond Smart Cities, emerging design and technologies".  Et j'ai vu dans l'un des modules apparaître Arnaud dont le nom laissait peu de doute sur son origine française... Un chercheur français associé au MIT et spécialiste de la modélisation de données pour les villes? Il fallait bien sûr que l'on ait cet échange là dans Felicity !  Avec Arnaud on a parlé de modélisation de données et des projets qu'il a pu mener dans différents pays, avec des finalités très différentes mais des résultats toujours incroyables.  Ce que j'ai aimé dans l'approche et l'outillage proposé par le MIT Media Lab et par Arnaud c'est qu'il propose une aide à la décision ludique et facile à appréhender pour tous y compris pour le grand public.  Alors les données pour mieux décider la ville, c'est parti!  => Lien d'inscription à la newsletter (à la sortie de chaque épisode, des infos en plus exclusives) : https://podcast.ausha.co/felicity?s=1 

En novembre 1969, le cadavre d’un jeune homme est retrouvé sur la falaise de Landemer dans le Cotentin (Manche). Le journaliste Philippe Bertin revient sur l’une des plus étranges énigmes criminelles de Normandie. Une affaire irrésolue à ce jour. Serge Le Petit était scolarisé au Lycée Grignard de Cherbourg. Le jeune homme de dix-sept ans a été retrouvé mort, abattu comme un chien, un jour de novembre 1969. Son corps inerte gisait sur la falaise de Landemer, en contre bas du sentier des douaniers de la Hague (Manche).Plus de cinquante ans après les faits, cette affaire criminelle reste non résolue. Le ou les assassins de Serge Le Petit n’ont jamais été identifiés et retrouvés. Le mobile du crime est lui aussi une énigme.Podcast by Tendance Ouest.

A l'occasion du lancement de la semaine des mathématiques 2013, les élèves des lycées Millet, Grignard et Tocqueville de Cherbourg-Octeville ainsi que le lycée professionnel Sauxmarais de Tourlaville présentent leurs recherches en mathématiques autour de thématiques liées à la mer.

In theis episode we go pretty in-depth into the Grignard reagent.  A little lecture followed by five examples on the virtual whiteboard.  In our site of the week, we proudly/arrogently talk about the new class notes bank that we created for organic chemistry students.  It has over 70 sets of class notes from around the US and allows you to vote on the ones you like.  Found at organic chemistry tutorials, we think it is pretty helpful.  For more organic chemistry help, please see our main site.

Imines are pervasive in chemistry and biology, playing key roles both the in artificial Strecker synthesis of amino acids and their biosynthesis by L-glutamate dehydrogenase and by transamination. Imines are also involved in Stork’s [gr]α-alkylation and acylation of ketones by way of enamine intermediates. Oxidation and reduction in organic chemistry can involve actual electron transfer, when ion-radical intermediates are involved as in the formation of Grignard reagents or in the pinacol reduction. But more often in treating the covalent molecules of organic chemistry atomic oxidation states are used as an artificial bookkeeping device that helps suggest reagent choice for transformations that do not involve literal electron transfer. Oxidation states are assigned by pretending that covalent bonds between different atoms are purely ionic. Complete course materials are available at the Open Yale Courses website: http://oyc.yale.edu This course was recorded in Spring 2011.

http://webs.anokaramsey.edu/aspaas/2061/video/19.7%20Addition%20of%20Grignard%20and%20hydride%20reagents%20-%20alcohol%20formation-0.m4v Sun, 27 Feb 2011 10:38:06 -0600

http://webs.anokaramsey.edu/aspaas/2061/video/17.5%20Alcohols%20from%20the%20Grignard%20reaction-0.m4v Fri, 11 Feb 2011 02:05:06 -0600 Higher Education

http://webs.anokaramsey.edu/aspaas/2061/video/10.7%20Grignard%20reagents.m4v Fri, 12 Nov 2010 09:57:02 -0600 Higher Education

Aldehyde and ketone nomenclature; preparation of aldehydes and ketones; oxidation;hydration; cyanohydrin formation; Grignard and hydride reactions; imine and enamine formation; acetal formation; Wittig reaction; conjugate addition; spectroscopy

Nomenclature; acid-base properties; synthesis of alcohols from alkenes; reduction of carbonyl compounds; Grignard reaction; conversion of alcohols into alkyl halides and tosylates; dehydration and oxidation of alcohols; protection; spectroscopy

Nomenclature and structure of organohalides; radical halogenation; preparation of organohalides; Grignard and Gilman reagents

A synthetic access to polymagnesiated aromatics and heteroaromatics via multiple magnesiations was developed, their reactivity towards different electrophiles was explored. A diatereoselective synthesis of functionalized cyclopropane carbenoids was developed. Soluble Lanthanide soloutions were prepared and used in the addition reactions of Grignard reagents to carbonyl compounds.

The preparation of polyfunctinalized arynes has been achieved by the controlled elimination of readily generated 2-magnesiated aryl arylsulfonates obtained by a low temperature halogen/Mg-exchange starting from the corresponding iodides. New types of Grignard reagents via the addition of magnesium aryl thiolates, amides and selenides to arynes and heteroarynes have been prepared. An easy access to highly functionalized arylmagnesium reagents prepared by direct magnesiation of carbocyclic aromatic rings with TMPMgClLiCl was developed.

Demonstration of the formation of methyl magnesium iodide

In dieser Dissertation wurden Kobalt-katalysierte Aryl-Aryl-Kreuzkupplungen zwischen funktionalisierten magnesium- oder kupferorganischen Reagenzien und Arylbromiden, -chloriden, -fluoriden und -tosylaten durchgeführt. Außerdem wurden neuartige Ein-Topf-Synthesen zur Darstellung bororganischer Verbindungen und anschließender Palladium-katalysierter Suzuki-Kreuzkupplungen untersucht. Abschließend wurden funktionalisierte Aryl- und Heteroaryldisulfide durch Reaktion zinkorganischer Reagenzien mit Schwefelmonochlorid synthetisiert.

Im Rahmen der Dissertation „Funktionalisierte Grignard-Reagenzien und ihre Anwendung in Aminierungsreaktionen wurden insbesondere nitrofunktionalisierte Aromaten und Ihre Reaktionen mit Magnesiumorganylen untersucht. Im ersten Teil der Dissertation wurde die Kompatibilität der Nitrofunktionalität mit Grignard-Reagenzien untersucht, und es gelang die erstmalige Synthese von nitrofunktionalisierten Arylmagnesiumhalogeniden durch eine Iod/Magnesium Austauschreaktion. Die anfängliche Limitierung auf ortho-Iodnitroaromaten konnte durch Wahl geeigneter komplexierender Gruppen überwunden werden und ermöglichte die Synthese von meta- und para-funktionalisierten Nitroarylmagnesiumhalogeniden. Des weiteren konnten diese neuen Grignard-Reagenzien auch in übergangsmetallkatalysierten Kreuz-Kupplungs-Reaktion erfolgreich eingesetzt werden. Im zweiten Teil der Dissertation wurden neue Aminierungsreaktionen untersucht, die ausgehend von elektrophilen Stickstoffverbindungen zu Diarylaminen führen sollten. Es gelang die Synthese von funktionalisierten Diarylaminen durch die Reaktion von Nitroaromaten und aromatischen Grignard-Reagenzien. Diese Methode stellt eine hervorragende Alternative zu den übergangsmetallkatalysierten Aminierungsreaktionen dar, und ist auf Grund der Kompatibilität mit Halogenen (Cl, Br, I) und Triflaten als komplementärer Zugang äußerst interessant. Diese neue Aminierungsmethode wurde ausgiebig beforscht, und es gelang die Anwendungsbreite in der selektiven Monoaminierung von Dinitroaromaten, sowie in der Synthese mehrerer heterozyklischer Arylamine zu demonstrieren. Es konnte auch gezeigt werden, dass eine Ausweitung dieser Methodik auf Nitrosoaromaten möglich ist. Basierend auf diesen Ergebnissen wurde eine weitere Aminierungsreaktion entwickelt. Ausgehend von Arylazosulfonen ist es nun möglich, Nukleophile jeder Art zu addieren und nach anschließender reduktiver Spaltung des Hydrazin-Derivates die entsprechenden Amine zu isolieren. Diese Methode zeichnet sich durch ein erheblich erweitertes Anwendungspotential aus und ist nicht nur auf aromatische Magnesium-Organyle beschränkt. Bemerkenswerterweise zeigt diese Methode bisher keinerlei Einschränkungen gegenüber sterischer Hinderung. Auch hier konnten exzellente Selektivitäten erzielt werden bei einer enormen Bandbreite an funktionellen Gruppen. Abschliessend wurden 1,2-Dehydroaromaten und Ihre Anwendung in Aminierungsreaktionen untersucht.

This work has focussed on the preparation of functionalized heterocyclic organometallics. In the first part, functionalized zinc derivatives were used due to their high functional group tolerance. Thus various thymine derivatives have been prepared both in solution and on the solid phase. Alternatively, a new route to functionalized heterocyclic Grignard reagents was developed using a low-temperature halogen-magnesium exchange. Ester, amide and nitrile functions are tolerated and the resulting organomagnesium derivatives could be reacted with various electrophiles. Finally, we have attempted to perform low-temperature cross-coupling reactions using these functionalized Grignard reagents. 5.1- Synthesis of thymine derivatives Zincated thymine derivative 2 was prepared by zinc insertion from the corresponding bromide 4, readily available in four steps from uracil. Negishi cross-coupling reactions were then performed using zinc reagent 2 and various aryl iodides. N N O O Bn Bn 4 Br HN N H O O N N O O Bn Bn 2 ZnBr Ar - I Pd(dba)2 (2.5 mol %) N N O O tfp (5 mol %) THF, 25 °C, 12 h Bn Bn Ar 3a-j: 62-95 % THF, 0 °C Zn* Scheme 67. Preparation of thymine derivatives 3a-j using a Negishi cross-coupling reaction. Resin-attached aryl iodides were also suitable substrates and solid phase synthesis of thymine derivatives could be performed with high HPLC-purities (89-93 %). X O I N N O O Bn Bn X = O, NH R 8 (10 equiv) N N O O Pd(dba)2 (5 mol %) tfp (10 mol %) THF, 25 °C, 48 h Bn Bn R = CO2H, CONH2 ZnBr 2) TFA 1) 89-93 % HPLC purity Scheme 68. Solid phase synthesis of thymine derivatives. 5.2- Synthesis of functionalized heterocyclic derivatives using a low temperature halogen-magnesium exchange • Synthesis of pyridine derivatives Functionalized pyridinyl Grignard reagents were prepared using a low temperature iodinemagnesium exchange and trapped with electrophiles. Functional groups such as ester, amide or nitrile functions are tolerated in this process. N I FG 1) i-PrMgBr -40 °C 2) E+ N E FG 50-92 % FG = Br, CONR2, CN, CO2R etc. Scheme 69. Preparation of functionalised pyridines using a low temperature iodine-magnesium exchange. The bromine-magnesium exchange is less general than the iodine magnesium-exchange and electron withdrawing groups are often necessary to accelerate the exchange reaction. However, 2-bromo and 3-bromopyridine were suitable substrates due to the π deficient character of these heterocycles. N Br 1) i-PrMgBr THF, rt, 6 h 2) E+ N E 72-75 % Scheme 70. Preparation of pyridine derivatives using a bromine-magnesium exchange. • Synthesis of thiazole and thiophene derivatives A low temperature bromine-magnesium exchange was then used in the synthesis of functionalized thiazole and thiophene derivatives. N S Br OEt O Br 1) i-PrMgBr THF, -78 °C N S Br OEt O E 2) E+ S Br Br CO2Et 1) i-PrMgBr -40 °C, 0.5 h 2) S Br CO2Et 1) i-PrMgBr -40 °C, 0.5 h 2) E+ S E E CO2Et S Br Br EtO2C 1) i-PrMgBr -40 °C, 0.5 h 2) E+ S E Br EtO2C 58-81 % 68-88 % 74 % 62-71 % Br CuCN cat. Scheme 71. Preparation of thiazole and thiophene derivatives using a bromine-magnesium exchange. • Synthesis of dihydrobenzofurans and tetrahydrobenzazepines An access to dihydrobenzofurans, benzolactams and tetrahydrobenzazepines was developed using arylmagnesium reagents bearing an o-chloromethyl group. Cl MgBr CO2Et Br 83 % CuCN 2 LiCl cat. . Cl CO2Et RNH2 reflux, 24 h K2CO3, THF N CO2Et R Cl I 1) i-PrMgBr (1.0 equiv) THF -10 °C, 1.5 h 2) RCHO, -10 °C, 1 h then reflux, 12 h O R 55-94 % 54-75 % X = H, CO2Me NPh X 1) i-PrMgBr (1.0 equiv) THF -10 °C, 1.5 h 2) PhN=C=O O X = H, 96 % X = CO2Me, 75 % Scheme 72. Preparation of dihydrobenzofurans and tetrahydrobenzazepines using a low temperature iodine-magnesium exchange. • Low-temperature halogen-magnesium exchange on the solid phase The low-temperature halogen-magnesium exchange could also be performed on the solid phase using an excess of i-PrMgBr and was applied to the synthesis of various thiophene derivatives. 2) E+ 1) i-PrMgBr (10 equiv) THF, -40 °C 3) TFA S E O HO S O O Br 83-99 % HPLC-purity Scheme 73. Solid phase synthesis of thiophene derivatives using a low temperature brominemagnesium exchange.