Podcasts about environmental

On a hot summer day, there's nothing better than a dip in a cold pool. But you know who can ruin that for you? A scientist who studies pool chemistry. What chemical reactions are happening in that swimming pool when the water comes into contact with our bodily fluids and skin products? Environmental engineer Ernest Blatchley sits down with Flora Lichtman to discuss his findings after two decades of research, including how urine in a pool makes that chlorine smell, and his work to make the air of the Paris Olympics' indoor pools less toxic. Guest: Dr. Ernest Blatchley is a professor of environmental engineering at Purdue University, based in West Lafayette, Indiana. Other episodes you may enjoy: A ‘Dune'-Inspired Space Suit To Turn Astronaut Pee Into Water The Evolution Of An Enzyme Engineer Who Changed Chemistry Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What if the biggest obstacle to your health, happiness, and success isn't your diet, your habits, or even your circumstances—but your nervous system? In this powerful compilation episode, Darin brings together some of the most transformative insights from several of his most impactful solo episodes on neuroscience, nervous system regulation, meditation, behavior change, human connection, trauma healing, and purposeful living. Drawing from cutting-edge research in neuroplasticity, somatic experiencing, meditation science, behavioral psychology, polyvagal theory, and positive psychology, Darin explores how your environment, biology, and daily practices shape your thoughts, emotions, and ultimately your life. From rewiring childhood patterns and understanding why willpower fails, to regulating your nervous system, embracing vulnerability, cultivating meaningful relationships, and reconnecting with your deepest purpose, this episode offers a practical roadmap for creating lasting internal transformation. True health doesn't begin in the kitchen—it begins in the mind. What You'll Learn Why neuroplasticity proves you're never "stuck" How unresolved trauma becomes trapped in the nervous system The science behind Somatic Experiencing Why your environment shapes behavior more than willpower How to redesign your surroundings for success The measurable neuroscience behind meditation What happens when the brain's Default Mode Network quiets down Why genuine human connection changes your biology How vulnerability rewires your nervous system The relationship between purpose and long-term fulfillment Practical exercises for regulating stress and creating resilience Why true transformation starts from the inside out Chapters 00:00:00 – Welcome to SuperLife 00:00:32 – Sponsor: Fatty15 00:04:13 – Why your nervous system determines your quality of life 00:04:52 – Introducing this mental mastery compilation 00:05:24 – The five pillars of emotional and mental resilience 00:05:51 – Neuroplasticity proves your brain can change 00:06:33 – Childhood programming isn't your destiny 00:06:54 – Somatic Experiencing and healing stored trauma 00:07:51 – Why trauma stays trapped inside the nervous system 00:08:20 – What humans can learn from wild animals 00:09:16 – Practical steps for releasing stored stress 00:09:52 – Healing begins with nervous system awareness 00:10:08 – Why willpower is not enough 00:10:22 – Redesigning your environment for success 00:11:17 – Why behavior change usually fails 00:11:59 – Environmental cues shape automatic habits 00:12:41 – The science behind Nudge Theory 00:13:26 – Why your surroundings matter more than motivation 00:14:02 – Phones, notifications, and distraction loops 00:14:40 – Sponsor: Shakeology 00:16:27 – Mastering your internal environment 00:16:54 – The neuroscience of meditation 00:17:09 – Harvard's advanced meditation research 00:18:21 – What meditation changes inside the brain 00:19:24 – Understanding the Default Mode Network 00:20:34 – Neuroplasticity, immune function, and meditation 00:21:15 – Why meditation changes your entire body 00:22:28 – Meditation as one of the most powerful health interventions 00:22:47 – The loneliness epidemic 00:23:02 – Small acts of kindness that change your biology 00:23:38 – Dopamine, oxytocin, and meaningful connection 00:24:15 – Polyvagal theory and nervous system safety 00:24:52 – Vulnerability as a biological superpower 00:25:43 – Everyday moments that create connection 00:26:38 – Rewiring your nervous system through kindness 00:27:32 – Why vulnerability creates resilience 00:27:40 – The final piece: discovering fulfillment 00:28:07 – Finding your authentic self 00:28:58 – Why purpose improves well-being 00:29:37 – Reconnecting with the miracle of being alive 00:30:33 – Defining your core values 00:31:34 – Living in alignment with your purpose 00:32:11 – Building meaningful work and relationships 00:33:18 – True health is an inside job 00:33:43 – Final reflections and mental reset 00:34:07 – Closing thoughts     Thank You to Our Sponsors Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Shakeology: Shakeology-All in One Nutrition: Get 15% off with code SUPERLIFE at Shakeology.com.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences New Show: Roadmap to Happiness     Key Takeaway "Your nervous system shapes every part of your life—from your habits and relationships to your health, resilience, and sense of purpose. The good news is that it isn't fixed. Through neuroplasticity, intentional environments, meditation, vulnerability, meaningful connection, and conscious daily practices, you can literally redesign the way your brain and body respond to the world. Real transformation doesn't begin by forcing yourself to change—it begins by creating the conditions where change becomes natural."

In this episode of The Brainy Business podcast, Melina Palmer welcomes Dr. Jay Maddock from Texas A&M University to discuss the profound impact of nature on our health and well-being. As a professor in the Department of Environmental and Occupational Health and co-director of the Center for Health and Nature, Jay shares groundbreaking insights into how our environments influence our mental and physical health. Listeners will learn about the physiological benefits of spending time in nature and why integrating natural elements into our daily lives and workplaces is crucial, especially in today's world where burnout and stress are on the rise. Jay reveals fascinating research, including studies on forest bathing and the use of virtual reality to enhance our connection to nature, even for those who may not have easy access to green spaces. This episode is a must-listen for anyone interested in enhancing their personal well-being or creating healthier work environments. Jay's insights will inspire you to rethink how you incorporate nature into your life and the spaces you inhabit. In this episode: Discover the measurable health benefits of spending time in natural environments. Learn about the concept of forest bathing and its impact on stress reduction and burnout. Explore how virtual reality can simulate nature experiences for therapeutic benefits. Understand the importance of integrating natural elements into workplaces for enhanced productivity. Gain actionable tips on how to incorporate nature into your daily routine, regardless of your environment. Get important links, top recommended books and episodes, and a full transcript at thebrainybusiness.com/583. Looking to explore applications of behavioral economics further?  Learn With Us on our website. Subscribe to Melina's Newsletter Brainy Bites.  Let's connect: Send Us a Message Follow Melina on LinkedIn The Brainy Business on Youtube The Brainy Business on Instagram

Want to quit your job and build a real land investing business?

Episode Summary Bivalve aquaculture is increasingly being explored not only as a source of sustainable seafood, but also as part of a broader conversation about ecosystem services and coastal resilience. Emerging research in the United Kingdom is helping quantify how shellfish species such as mussels, oysters and clams remove nutrients from marine environments through natural biological processes, creating opportunities to better understand aquaculture's role in supporting water quality and environmental management. At the same time, this work emphasizes the importance of realism and balance. Nutrient removal through shellfish farming is not a replacement for traditional water treatment or a universal solution to eutrophication, but it may become one tool within a larger portfolio of approaches. The discussion explores how science, industry, policymakers and growers can collaborate to better measure environmental outcomes while continuing to strengthen seafood production, ecosystem health and long-term resilience. Featured Guest Konstancja Woźniacka — Policy Advisor (Bivalves), Seafish Key Topics Covered Understanding ecosystem services in seafood production How bivalves naturally remove nutrients from coastal waters The relationship between eutrophication and marine ecosystem health Quantifying environmental benefits in shellfish aquaculture Differences in nutrient removal across species and farming methods Environmental and economic approaches to valuing nutrient removal Lessons from nutrient credit and ecosystem service programs Challenges to scaling environmental outcomes in shellfish farming The importance of localized research and environmental conditions Building public awareness around the broader value of seafood systems Key Takeaways Shellfish aquaculture can provide benefits beyond food production. Bivalves improve water quality through natural filter-feeding processes. Nutrient removal performance varies by species, location and cultivation method. Ecosystem services require careful measurement to avoid oversimplification. Environmental value and commercial viability must remain aligned. Collaboration across industry, science and policy is essential. Incremental solutions can still make meaningful contributions to marine health. Links and Resources Mentioned Seafish Website Chesapeake Bay nutrient management and oyster restoration initiatives Check out our website!: https://www.globalseafood.org/podcast Follow us on social media! Twitter | Facebook | LinkedIn | Instagram If you want to be more involved in the work that we do, become a member of the Global Seafood Alliance: https://www.globalseafood.org/membership/   The views expressed by external guests on Aquademia are their own and do not reflect the opinions of Aquademia or the Global Seafood Alliance. Listeners are advised to independently verify information and consult experts for any specific advice or decisions.

Daniel Foor returns to Sounds of SAND for a wide-ranging conversation that moves from his own winding spiritual path to the urgent question of why so many spiritual teachers stay silent in the face of injustice. A doctor of psychology, initiated priest in the Yoruba Ifá tradition, and practicing Muslim, Daniel makes the case that animism is the antidote to human supremacy, that Islam is fundamentally a relational and earth-honoring tradition, and that genuine spirituality cannot retreat from the political realities of our time. Along the way, he speaks candidly about ancestral healing, decolonization, the genocide in Gaza, and what it means to become "regular-sized" in a culture built on separation. Topics 00:00 — Welcome back & reconnecting with SAND 00:01 — Daniel's path: shamanism, psychology & many lineages 00:04 — Animism as the antidote to human supremacy 00:09 — Environmental problems are human behavior problems 00:10 — Is Islam animist? Sufism & the heart of the tradition 00:15 — Relationship is not worship: rethinking animism 00:20 — Giving the more-than-human a seat at the table 00:23 — "Blown-out" lineages & relearning relationship 00:26 — Spiritual responsibility & the silence around Gaza 00:31 — When silence becomes a moral failure 00:34 — The differential valuation of human life 00:38 — What Daniel is building: ancestral & earth ritual trainings 00:42 — Why pre-colonial ancestral connection matters 00:43 — Becoming "regular-sized": the antidote to extreme individualism 00:49 — Right relationship, humility & closing reflections Resources & Links Ancestral Medicine — Daniel Foor's website, courses, trainings & practitioner directory Ancestral & Lineage Healing Course Practitioner Directory — ancestral healing in 30+ languages, offered remotely with financial accessibility Ancestral Medicine: Rituals for Personal and Family Healing — book SAND Films Where Olive Trees Weep The Eternal Song (series of 12 films) Referenced Graham Harvey — scholar of the "new animism," referenced in the discussion of relational worldviews Surah Al-Tin (The Fig) and the animist verses of the Quran — referenced throughout the conversation on Islam as a relational tradition Contact SAND podcast@scienceandnonduality.com Support the mission of SAND and the production of this podcast by becoming a SAND Member

Most health issues don't appear overnight. Long before a diagnosis is made, the body often provides subtle clues that something needs closer attention. On this episode of The Dr. Hyman Show, I talk with double board-certified fertility physician Dr. Natalie Crawford about her new book, The Fertility Formula, and why fertility and hormone health can reveal far more about your health than many people realize. We discuss: Why the menstrual cycle may be one of the clearest indicators of overall health How sleep, stress, and insulin resistance may be affecting your hormones The overlooked symptoms that may signal deeper dysfunction What many women get wrong about PCOS and hormone health Practical strategies to support fertility, reduce inflammation, and improve long-term health Health challenges don't begin when symptoms become impossible to ignore. They often start years earlier. Being able to recognize those signals is one of the most effective ways to take a proactive approach to your health. Looking for a place to start? My 10-Day Detox is designed to help reduce inflammation, reset your metabolism, and build a stronger foundation for long-term health. View Show Notes From This Episode Sign up for Dr. Hyman's Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health - https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by BIOptimizers, Paleovalley, Perfect Amino, Rho, Sunlighten, and Pique. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Head to paleovalley.com/hyman to save 15% off your first order today. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Head over to rhonutrition.com and use code HYMAN to get 20% off their entire product line. Visit sunlighten.com and use code HYMAN to save up to $1600 today. Secure 20% off your order plus a free starter kit at piquelife.com/hyman (0:00) Infertility and fertility as indicators of overall health (3:10) Welcome Natalie Crawford and reframing fertility as health optimization (5:21) Access to fertility data, proactive health, and reproductive well-being (7:25) Menstrual cycle, hormonal communication, and ovulatory dysfunction (14:39) Inflammation's role in reproductive health (19:11) Reproductive health relevance beyond fertility and early warning signs (21:13) Medical training, coping mechanisms, and personal journey with celiac disease (23:48) Self-advocacy and higher infertility rates among female physicians (25:03) Personal experience with recurrent pregnancy loss (27:09) Inflammation, genetics, family history, and patient-centric care (35:38) Reducing inflammation, mitochondrial health, and top health recommendations (38:28) Sleep, stress, and their effects on fertility (47:25) Insulin resistance, diet optimization, and fertility (55:37) Environmental toxins, plastics, and hormone health (1:00:09) Unscented vs. fragrance-free products and toxin reduction (1:01:18) Fertility, aging, ovarian health, and AMH testing (1:07:38) Male fertility, sperm health, and testosterone (1:09:10) Resources for reproductive health and personalized care (1:10:16) Outro and sponsor acknowledgment

Here come the rats for all the rotting food!See omnystudio.com/listener for privacy information.

What if much of what you've been told about plastics, microplastics, and recycling isn't the complete story? In this thought-provoking episode, I sit down with Dr. Chris DeArmitt, internationally recognized scientist, author, materials expert, and founder of the Plastics Research Council, to explore one of the most controversial environmental topics of our time. Current research suggests that Americans may ingest and inhale between 74,000 and 121,000 microplastic particles annually, with exposure coming from the food we eat, the water we drink, and the air we breathe. Researchers note that these estimates are likely conservative because many common food sources have yet to be fully studied. Harvard Medical School's Harvard Medicine Magazine has also highlighted growing concern about microplastics in the human body and the need for further research into their potential health impacts. According to  Harvard Medicine Magazine (2023; Environmental Science & Technology, 2019.) At the same time, the United States generates approximately 35.7 million tons of plastic waste annually, while studies have estimated that only about 5% of plastic waste is effectively recycled, raising important questions about waste management, public policy, and environmental stewardship. (as noted by the: U.S. Environmental Protection Agency; Beyond Plastics/The Last Beach Cleanup, 2022.) Drawing upon decades of research and his review of more than 5,000 scientific studies, Dr. DeArmitt challenges conventional narratives surrounding plastics and the environment. As the author of The Plastics Paradox and Shattering the Plastics Illusion, he has built a reputation for separating evidence-based science from popular misconceptions, helping policymakers, businesses, and consumers better understand the realities of plastics, recycling, sustainability, and environmental impact. During our conversation, we discuss: • The science behind microplastics and what researchers actually know today • Common myths surrounding plastics and recycling • Why public perception often differs from scientific evidence • The environmental trade-offs associated with alternative materials • How misinformation can shape policy decisions • What an evidence-based approach to sustainability should look like Whether you're an environmental advocate, policymaker, business leader, or simply someone seeking a deeper understanding of the plastics debate, this episode offers a fascinating look at the data, the science, and the stories driving one of today's most important global conversations.   For more information: https://plasticsresearchcouncil.com/ LinkedIn: @ChrisDeArmitt Learn more about your ad choices. Visit megaphone.fm/adchoices

June 19, 2026- Environmental conservation law enforcement efforts have been undermined by a lack of resources and meaningful fines, but Democratic lawmakers are hoping to change that calculation. We discuss a pending legislative proposal with Matt Krug, a vice president with the union representing state environmental conservation officers.

Environmental attorney and author Clay Henderson breaks down the key players and history of state-funded conservation efforts in Florida and where protections stand today.

Environmental triggers like alcohol, toxins, and negativity shape brain health more than genes. See what reversed—and triggered—cognitive decline. #BrainInflammation #Exposome #AlzheimersTriggers #HealthTalks

Laura Aull, professor of English and linguistics and recent director of the English Department Writing Program at the University of Michigan, joins the Michigan Minds podcast to discuss "AI English," how generative tools disrupt the natural diversity of human speech and why automated hiring and housing systems inherit these linguistic biases. She also explores a largely unexamined downside to our rapid adoption of large language models: the massive, real-world carbon footprint generated by our daily digital conversations.Do you think people will care whether a human or a robot wrote the news or books we read?So far, humans care very much. And today I think we should care. And here are three reasons why I think we should. One is the environmental cost of the computer processing used with AI. Estimates suggest that if you pose a simple query to AI to ChatGPT, let's say versus to a search engine like Google, you're using 50 times the electricity for the simple query. I'm a serious scuba diver, and I know that the ocean should not get any warmer, and so I don't think we should normalize that kind of environmental impact.A second reason is bias. It's clear that AI English tools are biased against language too close to itself or too far away, so it penalizes some English users, including nonnative writers of English, who are more often flagged for plagiarism or more often flagged by AI detection tools even when they haven't used it. And those who use non-standardized dialect AI English don't know varieties from Jamaican English to Indian English.That leads to the third and final reason, which is that human and AI English are different. Human English has more variation and readability than AI English, meaning that human English has more varied kinds of dialect and genres and it is less grammatically dense and it's more humble. AI English is more formal, more impersonal, and more sure of itself. Hosted on Acast. See acast.com/privacy for more information.

Les guerres sèment la destruction, des vies humaines sont brisées, effacées, mais aussi des lieux de culte, des cités anciennes qui sont la mémoire historique des populations, leurs liens culturels et cultuels ancestraux : des églises, des mosquées, des temples, des musées, des sites archéologiques, des cimetières sont même parfois délibérément ciblés pour effacer cette mémoire, comme ce fut le cas lors de la destruction des mausolées à Tombouctou, au Mali, en 2012 par le groupe Ansar Dine, des sites antiques en Syrie et en Irak par l'organisation de l'État islamique en 2014 et 2015, ou les bouddhas géants de Bamiyan en Afghanistan par les Talibans en 2001. Certaines de ces guerres se déroulent en ce moment même, à Gaza, au Liban, en Ukraine, … parfois depuis de très nombreuses années. Tout récemment, des frappes russes à Kiev en Ukraine ont provoqué des morts dans la capitale et dans d'autres villes ciblées, un incendie a gravement endommagé le toit de la fameuse cathédrale de la Dormition, qui date du XIè siècle, dans le complexe orthodoxe de la Laure des Grottes, un site inscrit au patrimoine mondial de l'Unesco. Au sud du Liban, c'est la ville de Tyr qui a été ciblée récemment par des frappes israéliennes. Inscrits eux aussi au patrimoine mondial de l'Unesco depuis 1984, ces sites archéologiques antiques qui remontent au IIè ou IIIè siècle, ont subi des dommages dus aux bombardements. L'Unesco a d'ailleurs placé une quarantaine de biens culturels au Liban sous protection renforcée, un plan d'urgence a été présenté le 8 juin 2026, un signal envoyé à la communauté internationale sur la nécessité de protéger ces sites. En revanche, certains patrimoines sont ainsi définitivement perdus.  C'est le patrimoine au sens large qui est en péril dans les guerres : des bâtiments mais aussi des objets, des terres, contaminées par des produits chimiques, ou encore des ressources naturelles pillées qui continuent de nourrir les conflits.   Comment protéger, comment résister ? Les deux commissaires Elisabeth Essaïan et Mathilde Leloup ainsi que le commissaire associé Yves Ubelmann d'ICONEM ont proposé un parcours en trois thématiques dans cette exposition à la Cité de l'architecture et du patrimoine à Paris: effacer, résister, réparer (et transmettre). Dans cette émission, nous parcourons ces trois espaces, avec des illustrations de lieux détruits parfois reconstitués en films grâce à Iconem, fondée en 2013, spécialisée en numérisation 3D de sites patrimoniaux, qui a travaillé avec l'Unesco. Reportage avec les commissaires Elisabeth Essaïan et Mathilde Leloup, et le commissaire associé Yves Ubelmann, à l'exposition « Patrimoines en résistance. De Tombouctou à Odessa », à la Cité de l'architecture et du patrimoine, au Trocadéro à Paris (jusqu'au 3/01/2027).   Avec : - Elisabeth Essaïan, architecte, maîtresse de conférences en Théorie et pratique de la conception architecturale urbaine (TPCAU) à l'École nationale supérieure de Paris-Belleville, commissaire de l'exposition « Patrimoines en résistance, de Tombouctou à Odessa » - Mathilde Leloup, politiste, maîtresse de conférences en Science politique à l'Institut d'Études Européennes (IEE) de l'université Paris 8 et directrice adjointe du laboratoire CRESPPA, commissaire de l'exposition « Patrimoines en résistance, de Tombouctou à Odessa » - Yves Ubelmann, président et fondateur d'ICONEM (Imaging and Computation for Environmental and Monumental Heritage), commissaire associé de l'exposition « Patrimoines en résistance, de Tombouctou à Odessa » - Julien Bargeton, président de la Cité de l'Architecture et du Patrimoine. Extraits de reportages / RFI.   En images

What if one of the most important health crises affecting men today wasn't being caused by aging, but by the environment we live in? In this eye-opening solo episode, Darin Olien investigates the alarming decline in testosterone levels, fertility, and reproductive health among men worldwide. Drawing on decades of research, epidemiological studies, environmental science, endocrinology, and public health data, Darin examines the growing evidence connecting endocrine-disrupting chemicals, microplastics, sleep deprivation, chronic stress, poor lifestyle habits, and environmental toxins to declining testosterone levels across generations. From BPA, phthalates, atrazine, PFAS, and microplastics to sleep quality, circadian rhythms, cholesterol metabolism, cortisol regulation, and natural testosterone-supporting strategies, this episode explores what may be one of the most underreported public health issues of our time—and what men can do to take control of their health today.     What You'll Learn Why testosterone levels have been declining for decades The startling research on global sperm count decline How endocrine-disrupting chemicals interfere with hormone production Why BPA and phthalates may disrupt testosterone synthesis The role of atrazine, PFAS, and environmental toxins How chronic stress diverts resources away from testosterone production Why sleep may be the most important testosterone intervention The connection between cholesterol and hormone production How microplastics are being found throughout the human body The surprising relationship between statins and testosterone levels Natural lifestyle strategies that support healthy hormone production Practical steps to reduce environmental exposure and improve health     Chapters 00:00:00 – Welcome to SuperLife 00:00:33 – Sponsor: Fatty15 and cellular health 00:04:17 – The testosterone collapse explained 00:04:51 – Testosterone levels have been declining for decades 00:06:03 – Global sperm count decline and accelerating trends 00:07:02 – Why treating symptoms misses the root cause 00:07:27 – The hidden public health crisis 00:08:03 – Why low testosterone isn't just about aging 00:09:12 – Why hormone health affects longevity 00:09:53 – Low testosterone and increased mortality risk 00:10:35 – Testosterone's role in metabolism and cardiovascular health 00:11:27 – Endocrine-disrupting chemicals and hormone disruption 00:12:44 – BPA and its effects on testosterone production 00:13:59 – Phthalates and their impact on hormone pathways 00:16:00 – Glyphosate, atrazine, and pesticide exposure 00:17:07 – PFAS and reproductive health concerns 00:17:55 – Environmental toxins and population-wide effects 00:18:11 – Sponsor: Shakeology 00:20:02 – Cholesterol and hormone production 00:20:53 – Chronic stress and cortisol dominance 00:21:45 – Actionable solutions begin 00:21:56 – Why sleep is essential for testosterone production 00:23:07 – How sleep deprivation rapidly lowers testosterone 00:23:21 – Light pollution and circadian disruption 00:23:41 – Foods and nutrients needed for hormone health 00:24:23 – Microplastics and testicular tissue 00:24:53 – Statins and unintended hormonal consequences 00:25:39 – A practical testosterone sovereignty protocol 00:25:48 – Water filtration and reducing toxic exposure 00:26:13 – Eliminating plastics and fragrance chemicals 00:26:35 – Why organic food matters 00:26:45 – Sunlight and vitamin D 00:27:05 – Magnesium, omega-3s, and iodine 00:27:26 – Pine pollen and natural androgen support 00:28:01 – Tongkat Ali and ashwagandha 00:28:48 – Strength training and lifestyle interventions 00:29:10 – Habits that naturally support testosterone 00:29:27 – Darin's approach to healthy aging 00:29:37 – Plants, herbs, and common sense 00:29:51 – Reclaiming your health and sovereignty 00:30:00 – Final thoughts and closing message     Thank You to Our Sponsors Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Shakeology: Get 15% off with code DARINO1BODI at Shakeology.com.     Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien     Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness     Key Takeaway "The testosterone crisis may be about far more than aging. It may be a reflection of the modern environment itself—one increasingly saturated with endocrine-disrupting chemicals, chronic stress, poor sleep, circadian disruption, and toxic exposures. While many of these forces feel outside our control, the encouraging reality is that many of the most powerful interventions remain accessible: improving sleep, reducing toxic load, eating whole foods, getting sunlight, managing stress, exercising regularly, and reclaiming responsibility for our health. The goal isn't fear. The goal is awareness—and action."     Bibliography/Sources: The Decline — Primary Research Levine, H., Jørgensen, N., Martino-Andrade, A., et al. (2022). Temporal trends in sperm count: A systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Human Reproduction Update, 29(2), 157–176. https://doi.org/10.1093/humupd/dmac035 Lokeshwar, S. D., Patel, P., Fantus, R. J., et al. (2021). Decline in testosterone levels in men aged 15–40: Results from the National Health and Nutrition Examination Survey (NHANES), 1999–2016. World Journal of Urology, 39(2), 447–452. https://doi.org/10.1007/s00345-020-03227-1 Spital Clinic. (2026, March). Declining testosterone levels by generation. https://www.spitalclinic.com Travison, T. G., Araujo, A. B., O'Donnell, A. B., Kupelian, V., & McKinlay, J. B. (2007). A population-level decline in serum testosterone levels in American men. The Journal of Clinical Endocrinology & Metabolism, 92(1), 196–202. https://doi.org/10.1210/jc.2006-1375 Low Testosterone — Mortality & Disease Risk Muraleedharan, V., Marsh, H., Kapoor, D., Channer, K. S., & Jones, T. H. (2013). Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes. European Journal of Endocrinology, 169(6), 725–733. https://doi.org/10.1530/EJE-13-0321 Shores, M. M., et al. (2006). Low testosterone associated with increased all-cause and cardiovascular mortality. Archives of Internal Medicine, 166(15), 1660–1665. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/410754 Yeap, B. B., Marriott, R. J., Dwivedi, G., et al. (2024). Associations of testosterone and related hormones with all-cause and cardiovascular mortality and incident cardiovascular disease in men. Annals of Internal Medicine. https://doi.org/10.7326/M23-2781 Endocrine Disrupting Chemicals Associations between endocrine-disrupting chemical exposure and fertility outcomes: A decade of human epidemiological evidence. (2024). PubMed Central (PMC12299029). https://pmc.ncbi.nlm.nih.gov/articles/PMC12299029/ Hayes, T. B., Haston, K., Tsui, M., et al. (2002). Herbicides: Feminization of male frogs in the wild. Nature, 419, 895–896. https://doi.org/10.1038/419895a Mechanisms of testicular disruption from exposure to BPA and phthalates. (2020). Journal of Clinical Medicine, 9(2), 471. https://pmc.ncbi.nlm.nih.gov/articles/PMC7074154/ Meeker, J. D., Calafat, A. M., & Hauser, R. (2014). Urinary phthalate metabolites and their biotransformation products: Predictors and temporal variability among men and women. Journal of Exposure Science & Environmental Epidemiology. https://www.sciencedaily.com/releases/2014/08/140814124330.htm Zhao, Q., et al. (2023). Male reproductive toxicity of microplastics: Head and tail of the sperm. Science of the Total Environment, 872, 162181. https://doi.org/10.1016/j.scitotenv.2023.162181 Zhong, B., et al. (2024). Mixed EDC exposure associated with reductions in testosterone and free androgen index. Scientific Reports. https://doi.org/10.1038/s41598-024-76972-z Cortisol, Stress & the HPG Axis Bielohuby, M., et al. (2012). Swiss military cadets prolonged stress study. Psychoneuroendocrinology. Preprints.org. (2025). Sleep deprivation: A modifiable cause. https://doi.org/10.20944/preprints202505.0580.v1 SiPhox Health. (n.d.). Summary of Journal of Clinical Endocrinology & Metabolism data. https://www.siphoxhealth.com Viau, V. (2002). Functional cross-talk between the hypothalamic-pituitary-gonadal and -adrenal axes. Journal of Neuroendocrinology, 14(6), 506–513. https://doi.org/10.1046/j.1365-2826.2002.00798.x Sleep & Testosterone Leproult, R., & Van Cauter, E. (2011). Effect of 1 week of sleep restriction on testosterone levels in young healthy men. JAMA, 305(21), 2173–2174. https://jamanetwork.com/journals/jama/fullarticle/1029127 Reiter, R. J., et al. (2021). Melatonin and male reproductive health: Relationship to oxidative stress, mitochondrial function, and Leydig cell protection. Endocrine. Tan, D. X., Hardeland, R., Manchester, L. C., et al. (2023). Melatonin as a pleiotropic antioxidant hormone. Journal of Pineal Research. Nutrition — Zinc, Vitamin D, Cholesterol Corona, G., et al. (2010). Statin therapy and testosterone levels in men: A systematic review. The Journal of Sexual Medicine. Daniell, H. W. (2002). Hypogonadism in men consuming sustained-action oral opioids. The Journal of Pain, 3(5), 377–384. https://doi.org/10.1054/jpai.2002.126790 Pilz, S., Frisch, S., Koertke, H., et al. (2011). Effect of vitamin D supplementation on testosterone levels in men. Hormone and Metabolic Research, 43(3), 223–225. https://doi.org/10.1055/s-0030-1269854 Prasad, A. S., Mantzoros, C. S., Beck, F. W., Hess, J. W., & Brewer, G. J. (1996). Zinc status and serum testosterone levels of healthy adults. Nutrition, 12(5), 344–348. https://doi.org/10.1016/S0899-9007(96)80058-X Natural Testosterone Support — Botanical Evidence Pine pollen impacts testosterone-related symptoms in men. (2024). ACMCR Case Reports, 14(5), 1–9. Chinnappan, S. M., George, A., et al. (2021). Effect of Eurycoma longifolia standardised extract Physta on testosterone levels in ageing males: A randomised, double-blind, placebo-controlled multicentre study. Food & Nutrition Research, 65. https://doi.org/10.29219/fnr.v65.5647 Lazarev, A., & Bezuglov, E. (2021). Testosterone boosters intake in athletes: Current evidence and further directions. Endocrines, 2(2), 109–120. https://doi.org/10.3390/endocrines2020011 Leisegang, K., et al. (2022). Eurycoma longifolia (Tongkat Ali) improves serum total testosterone in men. Food & Nutrition Research. https://pubmed.ncbi.nlm.nih.gov/36013514/ Leitão, A. E., et al. (2021). 6-month double-blind RCT: Eurycoma longifolia 200mg + concurrent training. Maturitas. https://doi.org/10.1016/j.maturitas.2020.10.005 Lopresti, A. L., Smith, S. J., et al. (2019). An investigation into the stress-relieving and pharmacological actions of an ashwagandha extract. Medicine, 98(37), e17186. https://doi.org/10.1097/MD.0000000000017186 Pandit, S., Biswas, S., Jana, U., De, R. K., Mukhopadhyay, S. C., & Biswas, T. K. (2016). Clinical evaluation of purified shilajit on testosterone levels in healthy volunteers. Andrologia, 48(5), 570–575. https://doi.org/10.1111/and.12482 Saden-Krehula, M., Tajic, M., & Kolbah, D. (1971). Testosterone, epitestosterone and androstenedione in the pollen of Scotch pine Pinus sylvestris L. Experientia, 27(1), 108–109. https://doi.org/10.1007/BF02137731 Wankhede, S., Langade, D., Joshi, K., et al. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: A randomized controlled trial. Journal of the International Society of Sports Nutrition, 12, 43. https://doi.org/10.1186/s12970-015-0104-9

6/19/26 (Host – Josh Silver) MTA President Max Page: The Massachusetts Supreme Judicial Court's decision to bar the proposed income tax cut ballot initiative from appearing on the November ballot. Rep Lindsay Sabadosa & Wildlife Conservationist Emma Howard Boutiette: Legislation to stop SGARS (Second-Generation Anticoagulant Rodenticides) – highly potent rat and mouse poisons Rep Lindsay Sabadosa: Environmental Bond Bill – rewilded golf course in Williamsburg & Economic Development Bond Bill – Quantum Computing, digital revision Professor Austin Sarat: 50th Anniversary of reinstatement of the death penalty, where the death penalty stands now in the U.S. & the U.S. Iran Peace Deal Emily Boddy, Co-Founder of Reconnect Western Mass & the Founding Member of The Distraction Free Schools Policy Project: Northampton schools enacting a bell-to-bell cell phone policy Art Beat w/ Donnabelle Casis & Dean Brown, artist and owner of PULP Holyoke: Art exhibition feat Anna Helper, Sean Sullivan, & Roger Brouard now through July 12

What is your definition of food noise?Not the definition you've heard on social media. Not the definition used in marketing campaigns. Not the definition someone else gave you.Your definition.In this episode of The Food Noise Podcast, we explore one of the most talked-about terms in the health, fitness, and weight loss space today. Food noise has become a powerful marketing phrase, especially alongside the rise of GLP-1 medications, but what does it actually mean in your day-to-day life?We discuss the thoughts, feelings, anxieties, and experiences that may contribute to food noise, how outside influences shape our relationship with food, and why your experience may be very different from someone else's. We also examine the connection between food noise and modern weight loss marketing, while encouraging you to develop a deeper understanding of what is actually driving your thoughts and feelings around food.Rather than accepting someone else's definition, this episode invites you to get curious about your own.Topics Covered:• What food noise means to you• Why definitions matter• The marketing behind food noise• Food noise and GLP-1 medications• Thoughts and feelings around eating• Anxiety and decision-making around food• Environmental influences on eating• Social media and food messaging• Building awareness around food-related thoughts• Why everyone's experience is different• Creating a sustainable relationship with food• Building a forever active lifestyleContinue The ConversationIf you'd like to continue the conversation around food noise, join the live streams at:yourlevelfitness.com/streamThe live streams provide an opportunity to dive deeper into topics like food noise, eating habits, body image, confidence, and building a lifestyle you actually want to live.Thank you for listening to The Food Noise Podcast.The goal isn't to blindly accept someone else's definition of food noise. The goal is to understand your own experience, identify what is actually impacting your day-to-day life, and build a relationship with food that works for you.

Environmental lawyer and Animal Law Committee member Robin Happel hosts a discussion on noise pollution and noise law with Jamie Banks of Quiet Communities and ocean noise researcher Vanessa ZoBell. Jamie explains how chronic leaf-blower and land-care noise led her to found Quiet Communities. She describes gaps in federal, state, and local noise regulation, focusing on the 1972 Noise Control Act, the rise and 1982 defunding of EPA's Office of Noise Abatement and Control, and Quiet Communities' lawsuit to reactivate the program. Vanessa outlines major ocean noise sources (commercial shipping and seismic air-gun surveys) and impacts on marine life, including stress, masking, behavioral changes, and examples such as post-9/11 stress hormone reductions in right whales and sonar-linked beaked whale strandings. They discuss challenges of relying on A-weighted averages, low-frequency noise, communication barriers, voluntary and incentive-based programs, electrification of equipment, vessel speed reduction benefits, and long-term California soundscape findings tied to economic events and marine heatwaves, plus vulnerable human populations and environmental justice concerns. 00:42 Jamie on Quiet Communities 04:17 Vanessa on Ocean Acoustics 06:19 Major Ocean Noise Sources 08:34 Noise Control Act History 13:30 How Noise Harms Marine Life 18:23 Ecological Impacts on Land 20:34 Rethinking Noise Metrics 27:14 Shipping Slowdown Success 33:48 Incentives and Federal Tools 40:31 Decadal Soundscape Study 46:29 Vulnerable Groups and Justice

Environmental campaigners are celebrating news that contentious fishing reforms have been delayed until after the election. Sam Woolford, program lead for biodiversity advocates LegaSea spoke to Ingrid Hipkiss.

The Rebbe writes that the proposed rabbinic position is appropriate, but due to concerns about negative environmental influence, one should increase study in both revealed Torah and Chassidus. This will help withstand challenges, especially imagined ones, and positively impact the surroundings. https://www.torahrecordings.com/rebbe/igroskodesh/008/002/2252

We've been taught to treat chronic diseases as isolated problems to be diagnosed and managed. But these conditions may have more in common than conventional medicine has traditionally recognized. On this episode of The Dr. Hyman Show, I'm joined by physician and researcher Dr. Terry Wahls, who transformed her understanding of disease after developing progressive multiple sclerosis. We discuss the emerging science behind mitochondria, inflammation, nutrition, the microbiome, and why creating health may be just as important as treating disease itself. We explore: What Dr. Wahls discovered about cellular health while searching for answers beyond conventional treatment Why mitochondria may play a central role in conditions like MS, Alzheimer's, Parkinson's, depression, and chronic fatigue How food, sleep, movement, and stress directly influence inflammation, energy production, and brain health Why focusing only on symptom suppression may overlook the deeper biological dysfunction driving chronic disease What “creating health” actually looks like in practice—and how small daily habits can influence how you feel and function over time What makes this conversation so compelling is that Dr. Wahls' story challenges many of the assumptions we have about chronic disease and recovery. For me, it really highlights how profoundly nutrition, sleep, movement, and stress can shape the body's ability to adapt and recover over time. View Show Notes From This Episode Sign up for Dr. Hyman's Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by fatty15, Big Bold Health, Timeline, BON CHARGE, BIOptimizers, and Made In. Head to fatty15.com/HYMAN today and use code HYMAN for 15% off your 90-day subscription Starter Kit. Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order. Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Visit madeincookware.com and use code HYMAN10 for 10% off your order. (0:00) Dr. Terry Wahls' illness journey, Dr. Mark Hyman's intro, and sponsor mentions (2:54) Dr. Wahls and Dr. Hyman discuss their medical histories (4:00) Dr. Wahls' experience with multiple sclerosis (7:08) Dietary changes and physical improvements (9:09) Environmental factors in autoimmune diseases (11:17) Resistance in the medical system to new approaches (12:26) Integrating basic science into clinical practice (15:32) Mitochondrial support supplements (20:24) Mitochondria's role in energy-intensive tissues (22:11) Functional medicine and Dr. Wahls' continued health journey (23:49) Nutrient-focused dietary approach and recovery (26:13) Development and application of the Wahls diet (27:35) Nutrient-rich food categories and health benefits (30:11) NIH funding and functional medicine research potential (34:00) Success stories from the therapeutic lifestyle clinic (39:28) Creating health versus treating disease (44:10) Expanding research to other chronic illnesses (45:40) Latest clinical trials and future research directions (47:49) Advances in chronic disease treatment science (49:05) Predicting diet effectiveness: microbiome and genetics (50:00) Microbiome research and multiple sclerosis (51:18) A new theory of human biology in medicine (53:01) Creating health through lifestyle changes (55:13) Need for multimodal interventions in research (58:20) Funding challenges and philanthropy's role (59:08) Comprehensive approaches to complex diseases (1:01:05) Potential to reverse genetic diseases with lifestyle changes (1:07:24) Strategies for creating a healthy human (1:08:01) Upcoming research and initiatives by Dr. Wahls

Environmental law in the United States can be a double-edged sword. "I think that when people think about environmental law, very frequently what they mean is environmental protection, and what that misses is the other side of the coin, that there is a whole lot of law that is meant to exploit the environment," says law professor Brig Daniels. When Daniels and his writing partner Alejandro Camacho looked at the literature available on the development of environmental law in the United States, they found it lacking. "Most sort of focus only on environmental protection laws emerging from the 1970s or possibly the progressive era, missing frankly centuries of legal history that drove exploitation," says Camacho. They hope to remedy this with their new book, Lessons for a Warming Planet: A Vital History of US Environmental Law. From colonial expansion that deprived Native Americans of their ancestral lands to modern day battles over the Clean Air Act, Lessons for a Warming Planet offers a broad history of how environmental law has been developed. Change can happen gradually, or all at once. Camacho and Daniels have identified five different eras with dominant ideologies, some pushing towards protection and others towards exploitation. But in all eras, there were elements of both, the authors say. "It isn't just a black and white sort of binary of any of these eras," Camacho tells host Lee Rawles in this episode of the Modern Law Library. "And of course, what often happened is that an undercurrent in any given era becomes the dominant era in a subsequent era." The latest era of environmental law is one of contention, without a dominant force yet emerging. Lessons for a Warming Planet warns that either exploitation or protection could hold sway in the next era. "The thing that I hope that people understand is that looking back, one of the things that is so prevalent is that we didn't get the history that we had due to luck," says Daniels. "A big chunk of way we got our history was due to effort." In this episode of the Modern Law Library, Camacho, Daniels and Rawles discuss the Homestead Act, Cuyahoga River fires, and what Nixon really thought of pesky environmentalists.

Why is the global sustainability transition failing?In Part 3 of The Extractive Tapestry, we drop the raw data receipts on how the trillion-dollar modern war machine, corporate defense monopolies, and the military-industrial complex (MIC) structurally block renewable energy growth to protect private wealth and infinite expansion.From the 1993 "Last Supper" Pentagon dinner that consolidated our plastic-wrapped, fossil-fuel-dependent lifestyle, to the modern revolving door of defense tech-bros and billionaire WhatsApp groups colluding to crush public dissent—we are pulling back the curtain on the design of the fail.

For years we've been told that constantly thinking about food is a willpower problem.What if it isn't?In this episode, we're diving deep into the science of food noise: the constant thoughts, cravings, planning, negotiating, and mental energy that food can occupy.We break down the different types of food noise, including physical hunger, reward hunger, restrictive hunger, and environmental hunger. We discuss how hormones like ghrelin and leptin influence appetite, why sleep dramatically impacts hunger, how childhood experiences shape our relationship with food, and why some people naturally experience more food noise than others.Most importantly, we explore why food noise isn't a moral failure and why comparing yourself to someone whose brain processes hunger differently is a losing game.If you've ever wondered why food feels harder for you than it seems to for everyone else, this episode is for you.(00:00:51) Welcome to the podcast(00:08:59) What is food noise and why it isn't a willpower problem(00:15:22) Signs you may experience higher food noise(00:19:51) Physical hunger and recognizing real hunger cues(00:26:42) Reward hunger, dopamine, and emotional eating  (00:30:14) Restrictive hunger and why forbidden foods get louder (00:34:52) Environmental hunger and food cues everywhere(00:39:44) How diet culture increases food noise(00:46:05) Hunger hormones, body fat and biological differences (00:52:09) How sleep affects appetite(00:55:44) Food rewards, shame and judgement (01:00:24) Trauma and childhood experiences Want to leave the TTSL Podcast a voicemail? We love your questions and adore hearing from you. https://www.speakpipe.com/TheThickThighsSaveLivesPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The CVG Nation app, for ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠iPhone⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The CVG Nation app, for Android⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fitness FB Group⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Thick Thighs Save Lives Workout Programs⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Constantly Varied Gear's ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Workout Leggings⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Disclaimer: The information shared in this podcast is for educational and informational purposes only and is not intended as medical advice. The views expressed are those of the hosts and guests and should not be used as a substitute for professional medical diagnosis, treatment, or advice. Always consult your physician or qualified healthcare provider before making changes to your diet, exercise routine, medications, supplements, or healthcare plan.

Can toxic exposure lead to secondary VA disability conditions years later?In this episode, we discuss how toxic exposures — including burn pits, airborne hazards, particulate matter, solvents, fuels, and other environmental exposures — may contribute not only to primary service-connected conditions, but also to secondary medical complications over time.We break down: What “secondary conditions” actually mean in VA disability claims  How toxic exposure can create long-term systemic health effects  The difference between direct service connection and secondary service connection  Respiratory conditions linked to toxic exposure  Sleep apnea, chronic inflammation, and secondary complications  Mental health effects associated with chronic illness  Medication side effects and downstream conditions  Why medical evidence and chronology matter  Common mistakes veterans make when trying to connect conditions We also discuss the importance of individualized medical analysis and why medically defensible nexus opinions are becoming increasingly important in complex toxic exposure claims.Topics Covered Toxic exposure VA claims  Burn pit exposure  TERA claims  Secondary VA claims  Airborne hazards and burn pits  Chronic sinusitis  Rhinitis and asthma  Sleep apnea secondary claims  Toxic exposure medical evidence  Nexus letters  VA disability claims  Respiratory conditions  Chronic inflammation  Environmental exposure claims  Independent medical opinions About the PodcastThe Veterans Disability Nexus Podcast discusses VA disability medical evidence, nexus letters, DBQs, and the intersection of medicine and veterans disability claims. Hosted by medical professionals experienced in reviewing complex VA disability cases and independent medical opinions.DisclaimerThis podcast is for educational and informational purposes only and does not constitute legal or medical advice. Listening to this episode does not create a provider-patient relationship. Veterans should consult accredited representatives or qualified professionals regarding their individual claims or appeals.

Artificial intelligence is helping transform how the Energy Department approaches one of its most complex challenges: cleaning up nuclear waste. At the 2026 SCSP AI+Expo, Savannah River National Laboratory Associate Laboratory Director for Environmental and Legacy Management Eric Pierce joined GovCIO Media & Research to discuss how the lab is applying AI to improve environmental monitoring, reduce costs and accelerate cleanup efforts across the Savannah River Site. Pierce highlighted SRNL's Advanced Long-Term Environmental Monitoring Systems (ALTEMIS), which uses AI to predict contaminated groundwater plume movement. The technology has reduced monitoring requirements from quarterly sampling across 2,000 wells to a single annual verification sample, significantly lowering costs while maintaining confidence in environmental safety. He also discussed the lab's AI Accelerated Strategies and Solutions in Environmental Technology (AI-ASSET) initiative, which builds on ALTEMIS by collecting real-time, AI-ready environmental data. Currently, roughly 30% to 40% of the site's data is prepared for AI applications. Pierce also explained how SRNL is working with industry and government partners to modernize the remaining data and expand the use of AI-driven environmental cleanup technologies. The effort is part of a broader DOE initiative exploring how AI can advance scientific discovery, operational efficiency and innovation across the national laboratory system.  

What if the plastic container you're heating your leftover lunch in is actively rewriting your hormones? Environmental chemist Dr Paul Harvey unpacks the terrifying reality of microplastics, explaining how these tiny particles act like "micro knives," physically scratching our delicate gut lining and leaching creepy, hormone-disrupting chemicals into our system. Food scientist Dr Emma Beckett also weighs in, offering a much-needed reality check on balancing plastic panic with actual food safety. Then, we dive into "matressence," the massive, identity-shifting transition into motherhood. It turns out "baby brain" isn't a myth or a social media trend; real neuroimaging shows a mother's brain structurally prunes its grey matter to specialise for a baby, right as estrogen and progesterone drop off a perimenopause-level cliff. GET IN TOUCH Sign up to the Well Newsletter to receive your weekly dose of trusted health expertise without the medical jargon. Email here or leave us a voice note here. Ask The Doc: Ask us a question in The Waiting Room. Follow us on Instagram and Tiktok. Support independent women’s media and get our biggest offer of the year. Subscribe here for 30% off your annual Mamamia subscription. Code applied at the checkout. Offer ends June 30. CREDITS Hosts: Grace Rouvray & Dr Mariam Guests: Dr Paul Harvey & Dr Emma Beckett Senior Producer: Tahli Blackman Group Executive Producer: Ilaria Brophy Audio Producer: Jacob Round Social Producer: Elly Moore Mamamia acknowledges the Traditional Owners of the Land we have recorded this podcast on. Information discussed in Well. is for educational purposes only and is not intended to provide professional medical advice. Listeners should seek their own medical advice, specific to their circumstances, from their treating doctor or health care professional.See omnystudio.com/listener for privacy information.

Ep 105 | Have you ever felt like something was off in your body—even when your labs came back "normal"? This conversation may offer a completely different perspective on why.In this Season 3 kickoff episode, Jen sits down with certified clinical nutritionist Ashley Meyer—one of the most influential people in her own healing story—to dig into Nutrition Response Testing, root cause healing, heavy metal toxicity, and why the environment inside your home may be a bigger piece of your health picture than you've been told.✨ This episode is for you if:You've been told everything looks "fine" but still don't feel wellYou're dealing with fatigue, thyroid issues, or symptoms nobody can explainYou're curious about heavy metal toxicity and how it shows up in the bodyYou want to understand nervous system health and what blocks the body from healingYou've heard of Nutrition Response Testing and want to know how it actually works

This week on Talk World Radio we're talking about what the U.S. military does to Hawaii and what Hawaii could be without a massive military occupation. Our guest, Christine Ahn, is an Associate Fellow at the Institute for Policy Studies. She is the Founder and former Executive Director of Women Cross DMZ, a global movement of women mobilizing to end the Korean War and ensure women's leadership in peace building. In 2015, she led 30 international women peacemakers across the De-Militarized Zone (DMZ) from North Korea, which was the subject of the award-winning 2023 PBS documentary, Crossings. IPS and a number of partners have released a new report called "The True Cost Of The U.S. Military In Hawaiʻi: A Comprehensive Analysis of the Economic, Environmental, Strategic, and Social Impacts of the U.S. Military Presence in Hawai'i." See: https://www.ips-dc.org/report-true-cost-of-u-s-military-bases-in-hawaii

I asked Thiago Moraes, North America Sales Manager for Cultiva, what's happening in blueberries during this stage that makes them vulnerable to environmental stress?

The rapid proliferation of plans to build large data centers across the USA is a massive story with major consequences. So today, Caroline Gleich talks about what is happening in Utah and beyond; getting attacked by ‘Mr. Wonderful' on national TV; and more. We also discuss her experience running for U.S. Senate, and why we need more good people to get involved in local politics.Note: We Want to Hear From You!We'd love for you to share with us the stories or topics you'd like us to cover next month on Reviewing the News; ask your most pressing mountain town advice questions, or offer your hot takes for us to rate. Email us at: info@blisterreview.com RELATED LINKS:BLISTER+ Get Yourself CoveredSee our Updated Mtn Bike Buyer's GuideEnter Our Free Weekly Gear GiveawaysRESOURCES:Patagonia Action WorksErin Brockovich Data Center SiteVote411.orgBallotReady.org Local Journalism!TOPICS & TIMES:Caroline's Background (2:54)The Data Center Debate (9:10)Utah's Data Center Controversy (16:13)Environmental & Community Impacts of Data Centers (20:43)The AI Arms Race and Its Implications (24:16)What is Real “Progress”? (30:53)Where to Find Facts, Not Misinformation? (35:35)What can be done right now in Utah? (44:26)Caroline's Experience of Running for Senate (45:59)The Promise of Local Politics (54:36)CHECK OUT OUR OTHER PODCASTS:Blister CinematicCRAFTEDBikes & Big IdeasGEAR:30 Hosted on Acast. See acast.com/privacy for more information.

Residents in Galena, Kansas, are worried that noxious smells and a smoldering fire at the town's landfill are polluting the air and affecting their health. They are pushing for more testing to ensure the environment in their southeast Kansas town is safe.

I keep being accused of using AI. I've even been accused, more than once, of being AI-generated. So I owe you something better than irritation: an actual explanation of where I stand.In this episode, I work through the real concerns: the scraping of artists' work, the environmental cost, algorithmic bias, the fear of job displacement, the worry about deskilling, and argue that every one of them is a problem of how, not of whether. They are arguments for regulation, not for personal abstention. I talk about my own practice (yes, AI images sometimes; yes, Grammarly; no, not the writing or the thinking), about teaching at university in the middle of all this, and about why, as an anthropologist, I think this debate is really a debate about authorship and authenticity wearing a technological costume.The question, in the end, was never if AI. It was always, only, how.CONNECT & SUPPORT

One in four Clare farms failed environmental inspections last year. New EPA figures shows the local authority inspected 221 farms in this county in 2025, with 25% failing initial inspections and 75% failing on follow-up visits. The Environmental Protection Agency says most failures were caused by uncontrolled run-off from farmyard manure, inadequate management of silage pits and slurry and effluent discharging to groundwater. Clare IFA Chair Stephen Walsh says there are a number of proactive steps farmers can take.

1. ActBlue Investigation Allegations ActBlue is a major Democratic fundraising platform. The CEO pleaded the Fifth Amendment repeatedly during congressional testimony. There are allegations of illegal foreign donations, including possible contributions from foreign nationals. Congressional Republicans are investigating whether ActBlue: Allowed foreign donations Misled Congress Failed to implement fraud safeguards 2. Southern Poverty Law Center (SPLC) Controversy Being investigated for funding extremist groups (including the KKK) via informants. Allowing funds to allegedly support activities like cross-burning (as claimed in DOJ allegations). The CEO is described as evasive during testimony, deferring to legal proceedings. Includes a segment about questioning the CEO on a politician with a Nazi tattoo. 3. Missing Migrant Children & Immigration Policy the Biden administration: Lost track of hundreds of thousands of migrant children. Failed to vet sponsors receiving children. Many children were subjected to abuse, forced labor, or trafficking. The Trump administration has allegedly recovered 146,000+ children. Democratic immigration policies are enabling harm. Lists votes where Democrats allegedly opposed deportation policies for certain offenders. Used to argue Democrats are: Soft on immigration enforcement Prioritizing undocumented immigrants over public safety 4. “Green New Deal” / Government Funding Criticism Discusses Department of the Interior actions to cut funding to: Environmental groups DEI-related programs Claims: Democrats funnel taxpayer money to allied nonprofits These groups then advance political agendas Describes this as corruption or misuse of funds Please Hit Subscribe to this podcast Right Now. Also Please Subscribe to the 47 Morning Update with Ben Ferguson and The Ben Ferguson Show Podcast Wherever You get You're Podcasts. And don't forget to follow the show on Social Media so you never miss a moment! Thanks for Listening YouTube: https://www.youtube.com/@VerdictwithTedCruz/ Facebook: https://www.facebook.com/verdictwithtedcruz X: https://x.com/tedcruz X: https://x.com/benfergusonshowYouTube: https://www.youtube.com/@VerdictwithTedCruzSee omnystudio.com/listener for privacy information.

Leila Philip discusses the ancient Algonquin legend of Great Beaver, an environmental parable about resource hoarding and the creation of the Connecticut River Valley. The story reflects traditional ecological knowledge, emphasizing the beaver's immense power to control the water cycle and shape resilient landscapes. (3)1890

Send us Fan MailIn this thought-provoking Floc It Friday episode, Rudy Stankowitz takes a step away from chemistry myths, manufacturer sound-offs, and social media debates to explore a topic that has generated considerable discussion in both the pool industry and online communities: natural swimming pools. Drawing from four peer-reviewed scientific studies provided by Professor Charles Gerba, Rudy examines what the current scientific literature actually says about biological water treatment systems, pathogen control, microbial communities, and public health.Before diving into the science, Rudy also shares a personal message recognizing National PTSD Awareness Month, discussing the unseen challenges many industry professionals carry and reminding listeners that they are never alone in their struggles. In This Episode Why natural swimming pools represent a fundamentally different philosophy from traditional disinfected pools  The role of biological treatment systems, regeneration zones, gravel beds, and microbial communities  A review of a documented 2001 German outbreak involving more than 200 illnesses associated with a public nature-like swimming pond  What researchers discovered about swimmer exposure, water ingestion, and viral transmission  The findings of a Canadian risk assessment examining pathogen behavior in natural swimming ponds  How filtration rates, turnover times, and treatment efficiency influence health outcomes  The potential role of UV disinfection and why questions remain about its interaction with biological ecosystems  Research from Spain examining microbial populations and fecal contamination in natural swimming pools  Wildlife as a potential source of contamination in recreational waters  The importance of biofilms and the complex microbial communities that inhabit them  Why cyanobacteria, algae, and aquatic microbiology continue to raise important scientific questions  The challenges of identifying microbial populations without site-specific testing  What a 2024 One Health review reveals about algae, cyanobacteria, recreational water quality, and public health  The difference between visible water quality and the unseen biological processes occurring beneath the surface  Why scientific uncertainty is not a weakness, but a critical part of the scientific process Key TakeawayThe current scientific literature does not conclude that natural swimming pools are inherently unsafe, nor does it suggest that all questions surrounding their operation have been answered. Instead, the research consistently points toward the need for continued study, monitoring, challenge testing, and a deeper understanding of the biological communities responsible for water treatment. As Rudy emphasizes throughout the episode, science advances not by defending positions, but by asking better questions. Topics Discussed Natural swimming pools  Biological water treatment  Recreational water health risks  Pathogen control  Biofilms  Cyanobacteria  Algae ecology  Public health  Water quality monitoring  Environmental microbiology  Charles Gerba  Risk assessment  One Health research Mentioned During the Episode Professor Charles Gerba  Canadian Natural Swimming Pool Risk Assessment  German Nature-Like Swimming Pond Outbreak Investigation  Spanish Natural Swimming Pool Microbial Study  2024 One Health Review on Algae and Recreational Waters  National PTSD Awareness Month SponsorsThe 2026 Talking Pools Podcast Pool Industry Mentor Award is proudly supported by: BlueRay XL  LaMotte Company  Revved Up Apparel  Aqua Comfort Water Group Research on Natural Pools https://drive.google.com/file/d/1QpahWoVh3DDoNPwdw3oFsnbmUEj_umrS/view?usp=sharingConnect With Talking Pools

   SCP 7002's "wish" must not be granted. Content Warnings: End of the world, Environmental collapse, Mass starvation, Mind control Transcript Patrons April 16-18 Skye Gunter, Sarah McKinney, Hyperion, Tatum, Sami Kader. Cast & Crew  SCP Archives was created by Pacific S. Obadiah & Jon Grilz SCP-7002  was written by bigslothonmyface Script by Kevin Whitlock   Narrator - Jon Grilz Computer -  Rissa Montańez Dr. Willis - B. Narr Muyang Zhao - Melissa Lusk Interviewer - Isaiah Rothstein Bravo - Mick Wheaton Dialogue Editor - Nate Dufort Art - Eduardo Valdés-Hevia Composer- Newt Schottelkotte Theme Song- Mattie Roi Berger Sound Designer - Brad Colbroock Showrunner - Daisy McNamara Creative Director - Pacific S. Obadiah Executive Producer - Tom Owen Presented by Bloody FMwww.Bloody-Disgusting.comwww.SCParchives.com Patreon: https://www.patreon.com/scp_podStore: https://store.dftba.com/collections/scp-archivesInstagram: https://www.instagram.com/scp_pod/Bluesky: https://bsky.app/profile/scparchives.bsky.socialDiscord: https://discord.gg/tJEeNUzeZXTikTok: https://www.tiktok.com/@scppodYouTube: https://www.youtube.com/c/scparchivesNewsletter: https://pacificobadiah.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

As the Trump administration rolls back environmental regulations, we revisit a 2022 episode that explored the hidden cost of an invisible threat: air pollution.   SOURCES: Angela Duckworth, psychologist at the University of Pennsylvania. Michael Greenstone, economist at the University of Chicago, director of the Energy Policy Institute, co-director of the Climate Impact Lab. Stephan Heblich, economist at the University of Toronto. Andrea La Nauze, economist at Deakin University. Steve Levitt, professor emeritus of economics at the University of Chicago. Edson Severnini, economist at Boston College.   RESOURCES: "Most Polluted Cities," (American Lung Association, 2026). "Air Pollution and Adult Cognition: Evidence from Brain Training," by Andrea La Nauze and Edson Severnini (Journal of the Association of Environmental and Resource Economists, 2025). "Air Pollution and Student Performance in the U.S.," by Michael Gilraine and Angela Zheng (NBER Working Papers, 2022). "Billions of people still breathe unhealthy air: new WHO data," (World Health Organization, 2022). "Evolution of the Clean Air Act," by the United States Environmental Protection Agency (2020). "The Death of U.K. Coal in Five Charts," by Hannah Ritchie (Our World in Data, 2019). "The Colour of Pollution," (The Economist, 2014). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

To unlock subscriber-only content, visit: https://politicology.com/plus Géraldine Blanche (Intellectual Property Lawyer and PhD candidate in Intellectual Property Law at the Sciences Po Law School in Paris) joins Ron Steslow to discuss the politics of fashion and intellectual property law (01:26) Fashion in Politics  (05:36) Iteration, interpretation, and inspiration (09:47) The need for time in fashion and democracy (14:24) Environmental impact of fashion (26:42) The impact of AI on fashion Follow Ron on Twitter: https://twitter.com/RonSteslow Follow Géraldine on Instagram https://www.instagram.com/designedbylaw/  Learn more about your ad choices. Visit megaphone.fm/adchoices

On Today's Episode –In this episode of Blunt Force Truth, hosts Mark Young and Matt Umbarger break down the bizarre societal trends driving current headlines before diving deep into a fascinating, data-backed conversation with Dr. Chris DeArmit, a PhD in material science and a leading independent authority on environmental plastics.First, Mark and Matt tackle the shocking financial anomalies of the modern world. They discuss the controversial "profit-from-murder" crowdfunding phenomenon surrounding the Carmelo Anthony case, juxtaposing public outrage over Elon Musk's potential trillionaire status against a society that willingly donates hundreds of thousands of dollars to the families of violent criminals. The hosts also take aim at Bernie Sanders' new legislative push regarding AI taxation and the roots of societal envy.Then, the conversation shifts to hard science as they welcome Dr. Chris DeArmit to separate environmental fact from media fiction. If you've been told that you eat a "credit card's worth of plastic a week" or that microplastics are causing a global health crisis, prepare to have your worldview challenged. Backed by an exhaustive review of over 6,000 un-funded, peer-reviewed scientific studies, Dr. DeArmit reveals the counterintuitive truths of life-cycle assessments. Discover why replacing plastic actually increases green house gases, why plastic degrades far faster than the public is led to believe, and how activist organizations use fear to trigger our ancient "lizard brains" for profit.Tune in for all the Fun Chris DeArmitt, PhD, FRSC, FIMMM, is a materials scientist with 30+ yearsof industry experience and the world's most cited independent authorityon plastics, microplastics, and environmental science. Unlike industrylobbyists or activist groups, he has no funding agenda, only thousandsof unpaid hours spent tracing claims back to the primary literature.What he found contradicts nearly everything the public has been told.He is the founder of the Plastics Research Council, an expert witness,and the author of two books endorsed by scientists and professorsworldwide. His work has been featured on CBS 60 Minutes, BBC News,Sky News, and the Washington Post, among dozens of other outlets.He speaks to corporate leaders, policymakers, legal teams, healthprofessionals, and anyone whose decisions depend on getting thescience right. https://chrisdearmitt.com/ https://www.amazon.com/stores/Dr-Chris-DeArmitt-FRSC/author/B01KOQW2TQ?ref=ap_rdr&isDramIntegrated=true&shoppingPortalEnabled=true&ccs_id=e6bcf89a-7c73-4d9e-9169-c93ad8994655See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

My guest today is Patrick Hunnicutt, Assistant Professor of Environmental Administration at the University of Oregon.Patrick is the co author of a yet to be published research project called Poisoning the Well: Process, recognition, and opposition to environmental policy in rural America.His research argues that grievances rooted in procedural injustice, for instance, the perception of resource extraction dependent communities that they are excluded from meaningful participation in land management decisions affecting them, is a key and overlooked factor in rural resentment and environmental obstructionism.This one of my favorite conversations I've had in a long time, and went a bit long. So I'm going to share the whole interview, spread out over two episodes.In part 1, we'll go deep on Patrick's research, his impression of the fights around Oregon's State Forests, and how exclusionary public processes foster divides and resentment.As always, I would love to hear your thoughts about the show.  My email is coastrangeradio@gmail.com, please reach out anytime.https://www.instagram.com/coastrangeradio/

What if the plastic container you're heating your leftover lunch in is actively rewriting your hormones? Environmental chemist Dr Paul Harvey unpacks the terrifying reality of microplastics, explaining how these tiny particles act like "micro knives," physically scratching our delicate gut lining and leaching creepy, hormone-disrupting chemicals into our system. Food scientist Dr Emma Beckett also weighs in, offering a much-needed reality check on balancing plastic panic with actual food safety. Then, we dive into "matressence," the massive, identity-shifting transition into motherhood. It turns out "baby brain" isn't a myth or a social media trend; real neuroimaging shows a mother's brain structurally prunes its grey matter to specialise for a baby, right as estrogen and progesterone drop off a perimenopause-level cliff. GET IN TOUCH Sign up to the Well Newsletter to receive your weekly dose of trusted health expertise without the medical jargon. Email here or leave us a voice note here. Ask The Doc: Ask us a question in The Waiting Room. Follow us on Instagram and Tiktok. Support independent women’s media and get our biggest offer of the year. Subscribe here for 30% off your annual Mamamia subscription. Code applied at the checkout. Offer ends June 30. CREDITS Hosts: Grace Rouvray & Dr Mariam Guests: Dr Paul Harvey & Dr Emma Beckett Senior Producer: Tahli Blackman Group Executive Producer: Ilaria Brophy Audio Producer: Jacob Round Social Producer: Elly Moore Mamamia acknowledges the Traditional Owners of the Land we have recorded this podcast on. Information discussed in Well. is for educational purposes only and is not intended to provide professional medical advice. Listeners should seek their own medical advice, specific to their circumstances, from their treating doctor or health care professional.Support the show: https://www.mamamia.com.au/mplus/See omnystudio.com/listener for privacy information.

Your doctor probably didn't have answers to these questions. And that's not a slight. It's just the truth.This week I went straight to my Facebook community and asked for their real questions. What came back wasn't a list of random health curiosities. It was a snapshot of exactly what women are carrying right now. Thyroid confusion. Autoimmune diagnoses with zero real explanations. Environmental exposures nobody's investigating. Hereditary labels being used to shut the conversation down. Postsurgical symptoms written off as aging. And one woman doing the work one change at a time, just wanting to know if she's on the right track.She is. And so are you.I answered every single one of these questions. Because these are the root cause questions. The why questions. The ones worth asking.Inside this episode, we cover:Why your thyroid dose keeps going up every six months, and what it's actually signalingHow mold and environmental toxins drive chronic illness in ways the standard of care doesn't test forWhat I truly believe causes lupus, rheumatoid arthritis, and autoimmunity, and what actually helps people function betterWhy "hereditary" gets used as a conversation ender too quickly, and what to ask insteadHow to implement changes from the book without overwhelming your systemWhat surgical menopause does to your hormones, and why what you're experiencing is not just agingThe liver scarring question: what's actually possible, and what deserves honestyIf you've been handed a diagnosis with no explanation. If you've been told something is genetic, incurable, or inevitable. If you've been quietly asking "is there something more?" This episode is your answer.Yes. There is something more.Share this episode with one woman who's been told to just accept it. She deserves better than that.Your next steps are below:✨ Free Guide: 9 Hidden Signs Your Metabolism Is Stuck in Survival Mode www.drkaceywallace.com/hiddenmetabolicmess✨ Adrenal Optimization Test (see your cortisol rhythm + DHEA clearly) www.drkaceywallace.com/innercalm✨ Resiliency Reboot Program www.drkaceywallace.com/resiliencyreboot✨ Get the book: You Are Not Fine www.youarenotfine.comSupport the show

June 9, 2026- Politico New York reporter Marie French discusses environmental and energy headlines from the legislative session in Albany, including the horse trading involved in Gov. Kathy Hochul's effort to curtail the state's greenhouse gas reduction goals.

You can effectively design your environment by answering 4 questions: What's the real problem? What's the constraint? What are some ways to address the constraint? Which are you going to try?If you want to start taking the bigger and bolder action you need to actually change your life, or do the things you know you should be doing to improve your health or grow your business...This is for you!

What happens when a data-driven nutrition scientist sits down with one of the wellness world's biggest advocates for whole-food living and tackles some of the most controversial nutrition debates head-on? In this powerful and nuanced conversation, Darin Olien welcomes naturopathic doctor, researcher, educator, and science communicator Dr. Matthew Nagra for an evidence-based exploration of plant protein, muscle growth, fiber, seed oils, saturated fat, nutrition misinformation, social media influencers, and the future of nutritional science. Together they unpack why outcomes matter more than mechanisms, why plant proteins perform just as well as animal proteins for strength and muscle gain, the truth about seed oils and omega-6 fats, the overwhelming evidence supporting fiber consumption, and how people can learn to evaluate nutrition claims more critically in a world flooded with misinformation. This episode is a masterclass in scientific literacy, critical thinking, and practical nutrition. What You'll Learn Why plant protein performs just as well as animal protein for muscle growth The difference between nutrition mechanisms and real-world outcomes How social media amplifies nutrition misinformation Why Dr. Nagra began challenging viral dietary myths The strongest evidence supporting plant-based nutrition What the research actually says about seed oils The truth behind omega-6 to omega-3 ratios Why beef tallow isn't the miracle food social media claims How fiber may be the most important nutrient most people ignore What the Plant-Based Diet Index reveals about longevity The Stanford twin study and what it found about plant-based diets How to become more scientifically literate in a confusing nutrition landscape Chapters 00:00:00 – Welcome to SuperLife 00:00:33 – Sponsor: Tru Niagen and the science of NAD+ 00:02:37 – Introducing Dr. Matthew Nagra 00:03:22 – Why nutrition misinformation spreads so easily 00:05:15 – Matthew's mission to bring scientific literacy to nutrition 00:06:27 – Seeing the real-world consequences of viral health advice 00:07:03 – Why social media nutrition myths affect actual patients 00:08:06 – The evolution of nutrition science over the last decade 00:08:32 – Plant protein versus animal protein: where the debate began 00:09:17 – Essential amino acids and protein quality explained 00:09:40 – Why combining plant foods solves amino acid concerns 00:09:57 – Digestibility scores and the reality of protein absorption 00:10:36 – The landmark vegan versus omnivore muscle growth studies 00:11:15 – Why outcomes matter more than mechanisms 00:11:44 – The exercise analogy that explains nutrition science 00:12:30 – Social media fearmongering around lectins, oxalates, and plants 00:13:05 – Do nutrition influencers actually believe what they promote? 00:14:27 – The dangers of extreme dietary ideology 00:15:19 – Health misinformation versus harmless misinformation 00:16:01 – Why poor dietary choices can take decades to show consequences 00:16:27 – Sponsor: Fatty15 00:20:08 – Human adaptability and delayed health consequences 00:21:29 – Darin's vision for a more plant-forward future 00:22:17 – Plant-based momentum, backlash, and social narratives 00:23:14 – Media influence and public confusion around nutrition 00:24:14 – Why "just eat more plants" remains powerful advice 00:25:09 – How Matthew helps people understand scientific research 00:25:45 – "Doctor Nagra cured my science illiteracy" 00:26:12 – The power of live nutrition debates 00:27:16 – Why real-time debates reveal weak arguments 00:27:43 – Today's hottest nutrition controversies 00:28:07 – Ultra-processed foods and the growing nuance in the discussion 00:29:01 – What actually makes a food ultra-processed? 00:29:29 – Saturated fat, butter, and beef tallow 00:29:55 – The Minnesota Coronary Experiment controversy 00:31:13 – Cherry-picking studies versus evaluating the full body of evidence 00:32:03 – Why polyunsaturated fats continue to show benefits 00:32:38 – The strongest arguments for eating more plants 00:33:01 – Why fiber may be the most powerful nutrient in nutrition 00:33:42 – Patreon break 00:35:15 – The Plant-Based Diet Index explained 00:35:51 – Swapping animal protein for plant protein and reducing mortality risk 00:36:31 – Matthew's personal journey into plant-based nutrition 00:37:28 – Losing weight and improving asthma through dietary change 00:38:23 – Going fully plant-based and staying consistent 00:39:02 – The influence of Earthlings and animal ethics 00:40:14 – Commitment, discipline, and lifestyle change 00:41:05 – Following the evidence wherever it leads 00:42:08 – Being wrong, learning, and improving scientific understanding 00:42:49 – The joy of dissecting studies and uncovering nuance 00:43:39 – Checking bias and evaluating animal-food research fairly 00:45:37 – Environmental contaminants and modern food systems 00:45:58 – Matthew's 40,000-word seed oil review 00:46:48 – How seed oils are actually processed 00:47:26 – Bleaching, refining, and common misconceptions 00:47:58 – Omega-6 fats and inflammation myths 00:48:43 – The omega-6 to omega-3 ratio debate 00:49:24 – Why increasing omega-3s matters more than avoiding omega-6s 00:50:08 – Hexane, chemical extraction, and seed oil safety 00:51:11 – Beef tallow's resurgence and why it's happening 00:52:07 – What the evidence says about saturated fat 00:52:50 – Chocolate, stearic acid, and cardiovascular health 00:55:27 – New research on plant-based diets and biological aging 00:55:56 – Meeting Stanford researcher Christopher Gardner 00:56:33 – The Stanford twin study on plant-based eating 00:57:23 – Common criticisms of the twin study 00:58:03 – Funding accusations and scientific credibility 00:59:12 – Matthew's daily routine and nutrition habits 01:00:03 – How he tracks new nutrition research every morning 01:00:47 – Training, recovery, and building muscle on plants 01:02:13 – Soccer, strength training, and athletic performance 01:03:10 – Lane Norton, nutrition debates, and professional disagreement 01:04:22 – The future of nutrition communication and public education 01:05:00 – Final thoughts on evidence, health, and helping people think critically Thank You to Our Sponsors Truniagen: Go to www.truniagen.com and use code DARINOLIEN20 at checkout for 20% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Dr. Matthew Nagra Website: drmatthewnagra.com Instagram: @dr.matthewnagra Book an Appointment Here! Download: Free Cholesterol Guide Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "The most valuable nutrition skill in today's world may not be knowing what to eat—it's knowing how to think. In an age of viral misinformation, cherry-picked studies, and extreme dietary tribes, the ability to evaluate evidence, understand nuance, and focus on real-world outcomes becomes a superpower. The strongest dietary patterns consistently point in the same direction: more whole plant foods, more fiber, less dogma, and a commitment to following the evidence wherever it leads."  

This episode is brought to you by Audible, Fatty15 and Z Biotics. Sperm counts are down 50%. Fertility rates are collapsing. Miscarriages, hormone dysfunction, chronic inflammation, insulin resistance, environmental toxins, sleep deprivation, cannabis use, and modern stress are all colliding into what fertility physician Dr. Natalie Crawford, MD, author of The Fertility Formula, calls a growing reproductive health crisis. This conversation breaks down why fertility is one of the strongest indicators of overall health, how inflammation damages eggs, sperm, mitochondria, and hormones, why "healthy" people are still struggling to conceive, and the exact lifestyle, nutrition, testing, and environmental changes that can dramatically improve fertility outcomes for both men and women. Chase and Dr. Crawford also share deeply personal stories about pregnancy loss, the emotional toll of infertility, and how couples can better support each other through one of life's hardest journeys. You will learn: Fertility is a powerful marker of overall metabolic and cellular health Chronic inflammation is one of the biggest hidden drivers of infertility Sperm counts have dropped 50% over the last 50 years Cannabis use is strongly linked to sperm DNA damage and miscarriage risk TRT can significantly suppress or permanently impair sperm production Sleep may be the single most powerful fertility intervention available Women and men respond differently to fasting, cold exposure, and stress Insulin resistance is affecting far more "healthy" people than they realize Environmental toxins and endocrine disruptors are major fertility disruptors Men can dramatically improve fertility in as little as 90 days Pregnancy loss requires emotional support, community, and medical follow-up Follow Natalie @nataliecrawfordmd Follow Chase @chase_chewning -----  00:00 - The fertility crisis nobody is talking about 02:24 - Why fertility rates are rapidly declining 03:54 - Fertility as a marker of overall health 05:14 - Chronic inflammation explained 07:33 - The "walkie talkie" theory of hormones 10:10 - Detaching from the identity of being "healthy" 13:00 - TRT and male fertility risks 17:09 - Why men are 50% of the fertility equation 18:54 - Cannabis and sperm DNA damage 22:01 - Plastics, fragrances & endocrine disruptors 24:48 - Why men need to show up during fertility journeys 32:25 - Sauna use and sperm health 35:00 - Cold plunges, fasting & female hormones 37:34 - Best fertility-supporting nutrition strategies 43:53 - Why men can improve fertility in 90 days 44:44 - Women, egg reserves & aging explained 52:43 - The #1 thing you can do for mitochondrial health 55:11 - Fertility tests every person should know 01:00:17 - Why every man should get a semen analysis 01:04:11 - Should everyone freeze eggs and sperm? 01:09:15 - Chronic inflammation & insulin resistance explained 01:17:13 - How stress directly impacts fertility 01:19:11 - Practical ways to reduce inflammation 01:21:43 - The emotional reality of miscarriage & pregnancy loss 01:26:29 - What to do medically after pregnancy loss 01:29:08 - What "Ever Forward" means to Natalie ----- Episode resources: Audible - Get a FREE 30-day trial and start listening to your next favorite audiobook today ZBiotics - Use code EVERFORWARD10 to save 10% on the probiotic drink before drinking Fatty15 - Use code EVERFORWARD for an additional 15% off the 90-day starter kit Get Natalie's new book "The Fertility Formula"