Podcasts about number needed

This came up in our monthly subscriber Ask Me Anything. When I break down research I often talk about using absolute risk reduction and statistical significance to determine the efficacy of an intervention. Another number that helps determine efficacy is the Number Needed to Treat (NNT). This number helps us understand how many patients need to be treated with an intervention in order to avoid a single negative outcome.  Get full access to Weight and Healthcare at weightandhealthcare.substack.com/subscribe

Stephen Thomas discusses various aspects of the keto and carnivore diets, including the impact of cooking methods, the significance of blood glucose and ketone levels, and the nutritional benefits of meat. He emphasizes the importance of understanding health metrics and the adaptive nature of the body. The discussion also touches on personal experiences with dietary changes and the broader implications of nutrition on health. Chapters 00:00 Introduction and Housekeeping 00:31 Keto Brain Health Weekend Insights 03:41 Understanding Blood Glucose and Ketones 09:03 The Importance of Personal Experience Over Numbers 15:56 Debunking Myths About Saturated Fat 23:12 Cholesterol and Heart Disease: A Critical Analysis 28:51 Understanding the Number Needed to Treat 32:00 The Importance of Meat in Our Diet 37:39 Fasting: Benefits and Refeeding Protocols 50:32 Top Benefits of a Carnivore Diet 55:26 The Environmental Impact of Dietary Choices Sound Bites "It's all about the life or net benefit balance." "Don't sweat over the numbers." "The body is pretty adaptive."

In recent years, the "magic number" for retirement has shifted from $1 million to $1.5 million. This change, based on a recent survey, has left many wondering if they need to adjust their retirement plans. In today's episode, we dive into this topic to uncover whether this new figure is truly necessary for a comfortable retirement.   Check Out Our YouTube Channel: www.youtube.com/@brindleandbay Contact: Website - https://www.brindleandbay.com/ 214-988-9178

Contributors: Kali Olson PharmD, Travis Barlock MD, Jeffrey Olson MS2 Summary: In this episode of Pharmacy Phriday, Dr. Kali Olson joins Dr. Travis Barlock and Jeffrey Olson in studio to discuss a variety of interesting topics in the form of a segment show. Dr. Kali Olson earned her Doctorate of Pharmacy from the University of Colorado, Skaggs School of Pharmacy and completed a PGY1 residency at Detroit Receiving Hospital and a PGY2 residency in Emergency Medicine at Denver Health. She now works as an Emergency Medicine Pharmacist at Denver Health.  In segment one of the show, Kali and Travis answer the Get-To-Know-You questionnaire. In segment two, they work together to answer a series of pharmacy-based riddles. In segment three they play a “Balderdash” like game in which they guess the definitions of medical jargon. In segment four they play the Number Needed to Treat game, invented by the AFP podcast. And in segment five they work together to answer a question about a far-out scenario involving medications and time travel!   References ·       American Family Physician Podcast, https://www.aafp.org/pubs/afp/multimedia/podcast.html ·       Gragnolati, A. (2022, May 5). The Yuzpe method of emergency contraception. GoodRx. https://www.goodrx.com/conditions/emergency-contraceptive/yuzpe-method ·       Manikandan S, Vani NI. Holiday reading: Learning medicine through riddles. CMAJ. 2010 Dec 14;182(18):E863-4. doi: 10.1503/cmaj.100466. PMID: 21149530; PMCID: PMC3001539. ·       Riddle Me This: Mixing Medicine, https://peimpact.com/riddle-me-this-mixing-medicine/ ·       https://thennt.com/nnt/corticosteroids-treatment-kawasaki-disease-children/ ·       https://thennt.com/nnt/aspirin-acute-ischemic-stroke/ ·       https://thennt.com/nnt/tranexamic-acid-treatment-epistaxis/ ·       https://thennt.com/nnt/antibiotics-culture%e2%80%90positive-asymptomatic-bacteriuria-pregnant-women/   Produced, Hosted, Edited, and Summarized by Jeffrey Olson MS2 | Additional editing by Jorge Chalit, OMSII  

Originally Aired: 4/30/22On this vintage episode of Vitality Radio Podcast Jared rants about NNT, Number Needed to Treat, and Statin Drugs. He explains what NNT means and why Statin Drugs are not as safe and preventative as they seem.In the second half of the show, Jared explains Vitamins D3, K2, and Magnesium, why you need each individually, and why they work better together.Products:Vitamin D3Vitamin K2Magnesium GlycinateVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Twitter for educational purposes? Actually, yes! Listen in to hear how Timothy Gauthier, a social media savvy pharmacist and educator, uses social media in pharmacy education and professional development, and how you and your students can use it as a lifelong learning tool.  Host: Kathy Schott, PhD CEimpact Guests: Timothy Gauthier, PharmD, BCPS, BCIDP Antimicrobial Stewardship and Infectious Disease Pharmacist PGY2 Infectious Disease Pharmacy Residency Program Director Founder & Editor-in-Chief, www.Idstewardship.com Founder & Editor-in-Chief, www.LearnAntibiotics.com Timothy Gauthier reports he is a consultant for DoseMeRx, AntimicrobiaI Therapy, Inc., and Spectrum Mobile Health. Any relevant financial relationships have been mitigated. The views and opinions expressed in this podcast are that of the interviewee and do not necessarily reflect the policy or position of any former, current, or potential future employer.Get CE Click here to access the courseCPE Information At the end of this course, preceptors will be able to: Describe strategies for integrating social media into experiential learning Avoid common pitfalls associated with social media UAN: 0107-0000-22-233-H04-P Release Date: 06/01/2022 Expiration Date: 06/01/2025 Want more education on this and other precepting topics?  Watch for our new course release – Number Needed to Tweet: Using Social Media to Engage Experiential Learners Check out our Preceptor Library for a full suite of timely and relevant topics for pharmacy preceptors. Finally, follow our guest, Tim Gauthier, as he continues to engage learners through his social media presence: LinkedInTwitterInstagramBlog

On this week's episode of Vitality Radio Podcast Jared rants about NNT, Number Needed to Treat, and Stanton Drugs. He explains what NNT means and why Stanton Drugs are not as safe and preventative as they seem. In the second half of the show, Jared explains why Vitamins D3, K2, and Magnesium, why you need each individually, and why they work better together. Announcements from the show: Vitality Nutrition's Homepage: https://vitalitynutrition.com/ Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information within is not intended to diagnose, treat, cure or prevent any disease. The advice given is not intended to replace the advice of your medical professional.You can follow us at @vitalityradio on Instagram, Facebook, and Twitter. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. If you'd like to shop our visit please visit us at vitalitynutrition.com. Thank you!

Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Relapse of depression more likely after discontinuation of medication (number needed to treat to harm = 6). '

Drive with Dr. Peter Attia Podcast Notes It's a valuable skill to be able to sift through the noise and find the signal in scientific studiesThough meta-analyses summarize findings from previous studies, it's still prudent to look at each individual study to make sure they're sound – garbage in, garbage out (and vice versa)Observational studies are non-intervention studies looking at the outcomes of people and data to find patternsExperimental studies are intervention studies to determine safety and efficacy between groups of people assigned to intervention or control (non-intervention)The gold standard of experimental studies is a randomized controlled trial, ideally, double-blind so neither participant nor researcher knows who is assigned to intervention or controlWhile clinical trials are regulated by FDA, most of the world follows the same guidelines for Phases I – IVRead the full notes @ podcastnotes.orgIn this “Ask Me Anything” (AMA) episode, Peter and Bob dive deep into all things related to studying studies to help one sift through all the noise to find the signal. They define the various types of studies, how a study progresses from idea to execution, and how to identify study strengths and limitations. They explain how clinical trials work, as well as the potential for bias and common pitfalls to watch out for. They dig into key factors that contribute to the rigor (or lack thereof) of an experiment, and they discuss how to measure effect size, differentiate relative risk from absolute risk, and what it really means when a study is statistically significant. Finally, Peter lays out his personal process when reading through scientific papers. If you're not a subscriber and listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #30 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: The ever changing landscape of scientific literature [2:15]; The process for a study to progress from idea to design to execution [4:15]; The various types of studies and how they differ [7:30]; The different phases of a clinical trial [19:15]; Observational studies and the potential for bias [26:30]; Experimental studies: Randomization, blinding, and other factors that make or break a study [44:00]; Power, p-values, and statistical significance [56:15]; Measuring effect size: Relative risk vs. absolute risk, hazard ratios, and “Number Needed to Treat” [1:07:45]; How to interpret confidence intervals [1:17:30]; Why a study might be stopped before its completion [1:23:45]; Why only a fraction of studies are ever published and how to combat publication bias [1:31:30]; Why certain journals are more respected than others [1:40:30]; Peter's process when reading a scientific paper [1:43:45]; and More.

In this “Ask Me Anything” (AMA) episode, Peter and Bob dive deep into all things related to studying studies to help one sift through all the noise to find the signal. They define the various types of studies, how a study progresses from idea to execution, and how to identify study strengths and limitations. They explain how clinical trials work, as well as the potential for bias and common pitfalls to watch out for. They dig into key factors that contribute to the rigor (or lack thereof) of an experiment, and they discuss how to measure effect size, differentiate relative risk from absolute risk, and what it really means when a study is statistically significant. Finally, Peter lays out his personal process when reading through scientific papers. If you're not a subscriber and listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #30 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: The ever changing landscape of scientific literature [2:15]; The process for a study to progress from idea to design to execution [4:15]; The various types of studies and how they differ [7:30]; The different phases of a clinical trial [19:15]; Observational studies and the potential for bias [26:30]; Experimental studies: Randomization, blinding, and other factors that make or break a study [44:00]; Power, p-values, and statistical significance [56:15]; Measuring effect size: Relative risk vs. absolute risk, hazard ratios, and “Number Needed to Treat” [1:07:45]; How to interpret confidence intervals [1:17:30]; Why a study might be stopped before its completion [1:23:45]; Why only a fraction of studies are ever published and how to combat publication bias [1:31:30]; Why certain journals are more respected than others [1:40:30]; Peter's process when reading a scientific paper [1:43:45]; and More.

CHCA talks with Dr. Toby Rogers on his recent research into the FDA's Risk/Benefit analysis of the Pfizer product for children and the NNTV for children in order to save one life. The numbers will shock you. 0 – Introduction 1:38 – FDA meeting re; Pfizer shot for kids, Risk/Benefit analysis 4:40 – Ten Red Flags of the FDA's Risk/Benefit analysis 25:45 – Number Needed to Vaccinate (NNTV) 47:37 – VAERS: Explaining VAERS to counter the mainstream narrative that it is not a reliable source. 52:35 – Where do parents go to get objective information/articles about this product? 1:00:55 – Marketing Manipulation 1:08:00 – Ending on a positive note: Top 10 Things you can do today! https://tobyrogers.substack.com/p/ten-red-flags-in-the-fdas-risk-benefit https://tobyrogers.substack.com/p/what-is-the-number-needed-to-vaccinate Steve Kirch: https://stevekirsch.substack.com/ Pfizer EUA application: https://www.fda.gov/media/153409/download FDA and CDC guidance rules: https://www.cdc.gov/vaccines/acip/committee/downloads/Economics-Guidance-for-ACIP-2019.pdf FDA risk benefit analysis: https://www.fda.gov/media/153447/download Walach, Klement, & Aukema: https://cf5e727d-d02d-4d71-89ff-9fe2d3ad957f.filesusr.com/ugd/adf864_8c97b2396c2842b3b05975bfbd8254cb.pdf Kirsch, Rose, and Crawford: https://docs.google.com/document/d/1stq2nHFjAcMHhxJhWiXa33wl6x0Ga1qdIxodZnFixRw/edit# Autism Tsunami: the Impact of Rising Prevalence on the Societal Cost of Autism in the United States by Mark Blaxi

Here's an objective look at the latest science investigating the durability of immunity from prior infection plus results from serially testing antibodies after contracting COVID-19 in December of 2020. Related: Save your seat in the Blood Work MasterClass Live Training eClass This two-part live webinar and video eCourse will teach you about patterns and trends in your blood work to help optimize your health and lifespan. Live Training Tuesday, Nov 16th @ 5:00 PM PST Live Training Tuesday, Nov 30th @ 5:00 PM PST Follow this link to RSVP: https://courses.highintensityhealth.com/store/hgwDdo2p Links to resources and references: https://bit.ly/305VoS4 Time Stamps: 0:09 New CDC Study 1:07 Big Picture Overview 1:41 Antibodies 11 months later 3:05 CDC Study results differ from other data 3:26 T cell immunity 4:09 Innate VS Adaptive Immunity 5:05 Spanish Flu survivors have Abs 90 years later 5:50 Blood Work MasterClass Live 6:38 Testing Antibodies: how to do it 7:21 Why do we ignore prior infection 9:00 Number Needed to Treat in prior immunity VS Vaccine 9:58 Israel Data on reinfection rates 10:55 Cleveland Clinic study of 50,000 11:17 UCLA study of 6,000 12:11 Systemic Review of multiple studies o 13:30 Podcast recap References: Centers for Disease Control and Prevention. (2021). Laboratory-Confirmed COVID-19 Among Adults Hospitalized with COVID-19–Like Illness with Infection-Induced or mRNA Vaccine-Induced SARS-CoV-2 Immunity — Nine States, January–September 2021, 1–6. RESEARCH NEWS: Antibodies To 1918 Flu Found In Elderly Survivors https://www.npr.org/templates/story/story.php?storyId=93675590 BMJ, J. B.,. (2021). Vaccinating people who have had covid-19: why doesn't natural immunity count in the US? Bmj.com. http://doi.org/10.1136/bmj.n2101&domain=pdf&date_stamp=13-9-2021 Shenai, M. B., Rahme, R., & Noorchashm, H. (2021). Equivalency of Protection From Natural Immunity in COVID-19 Recovered Versus Fully Vaccinated Persons: A Systematic Review and Pooled Analysis. Cureus, 13(10). http://doi.org/10.7759/cureus.19102 Kojima, N. (2021). Necessity of COVID-19 Vaccination in Previously Infected Individuals: A Retrospective Cohort Study, 1–22. http://doi.org/10.1101/2021.06.01.21258176 Kojima, N. (2021). Incidence of Severe Acute Respiratory Syndrome Coronavirus-2 infection among previously infected or vaccinated employees, 1–11. http://doi.org/10.1101/2021.07.03.21259976 Kojima, N., Health, N. S. E. T.,. (2021). A Systematic Review of the Protective Effect of Prior SARS-CoV-2 Infection on Repeat Infection. Journals.Sagepub.com. http://doi.org/10.1177/01632787211047932  

How and why do we use summary statistics to explain clinical trials, and why are some statistics better than others for helping us understand what a drug might do? In this podcast, we talk about absolute risks, absolute risk reductions, and number needed to treat, and why they tend to be better statistics to use for understanding compared to odds, odds ratios and relative risk reductions.

In this episode, Ian discusses relative versus absolute risk ratios and number needed to treat (NNT). In it, he describes some of the ways each are used and under what conditions it might be best to use one over the other, as well as what precisely the NNT really means. Finally, he concludes with some thoughts about how interpreting regression output is bound to be a vital skill for DNP-prepared nurses to adequately translate the science of nursing into their practices.

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Hey Everyone, Today's topic we discuss the Men B vaccine, and how I apply the NNV/statistics to help add in the shared decision making process.

Professor Saba Balasubramanian talks about Relative Risk Reduction, Absolute Risk Reduction and Number Needed to Treat. Brought to you by CRAMSURG www.cramsurg.org Our tune is"Inspiring Optimistic Upbeat Energetic Guitar Rhythm" by Free Music | https://soundcloud.com/fm_freemusic Music promoted by https://www.free-stock-music.com Creative Commons Attribution 3.0 Unported License https://creativecommons.org/licenses/by/3.0/deed.en_US

Professor Saba Balasubramanian talks about Relative Risk Reduction, Absolute Risk Reduction and Number Needed to Treat. Brought to you by CRAMSURG www.cramsurg.org Our tune is"Inspiring Optimistic Upbeat Energetic Guitar Rhythm" by Free Music | https://soundcloud.com/fm_freemusic Music promoted by https://www.free-stock-music.com Creative Commons Attribution 3.0 Unported License https://creativecommons.org/licenses/by/3.0/deed.en_US

The AM1 crew along with their medical director, Dr. David Vitberg, meet to discuss TXA and it's role within prehospital medicine. Topics discussed include normal blood and clot physiology, the relationship of TXA, TPA, fibrin, thrombin, along with a robust discussion of recent studies that researched the efficacy of TXA. The discussion concludes with a discussion on the concept of a "Number Needed to Treat."

My guest this week is Charlie Gillihan, my youngest brother. At the time of this recording, Charlie was a few weeks away from graduating from medical school. I was interested in his take on medical education in the 21st century since he not only went to medical school but is an experienced teacher himself. Charlie was very open about his own experiences in a way that I think will be helpful to many people. It was a great discussion as we explored many issues related to learning, medicine, and stress, including: What medical school should look like in the twenty-first century Evidence-based medical education Fixed vs. growth mindset as learners The brain’s ability to learn even without our conscious effort The challenges of learning in medical school What it takes to get through medical school, vs. what it takes to be a doctor High rates of physician burnout and suicide Mental health training in medical school What to look for in a great primary care doctor The importance of being listened to as a patient How people heal, and how it's not often because of medical treatment Nortin Hadler and the Number Needed to Treat (NNT) measure (see TheNNT.com) How to promote a healthy gut microbiome Charlie referenced the Whipple procedure—here's a link to that if you're interested: Whipple procedure. He also highlighted Pamela Wible's work on physician suicide; here's her TEDMed talk about it: Why Doctors Kill Themselves. Our grandfather whom Charlie mentioned, Dr. Alec Spencer, was a doctor for over 50 years in a small town in eastern Kentucky. Here's a write-up about his life and what made him so beloved by his patients and community: The Doctor Will Hear You Now. Here's more information about the author Vinay Prasad. Charlie referenced his book, Ending Medical Reversal which is available on Amazon. For more from Nortin Hadler, see The Citizen Patient and Worried Sick. (A percentage of each purchase made through these affiliate links will be used to support the podcast, at no additional cost to you.)  Charlie was enthusiastic about a measure called the Number Needed to Treat (NNT), which determines the number of people needed to treat in order to change one outcome for the better. For example, if 100 people get a treatment and 10 show improvement, compared to 9 out of 100 who got the placebo, then the NNT would be 100. That is, for every 100 people treated, one person would show improvement who wouldn't have gotten better without the treatment. The Voltaire quote Charlie cited was, “The art of medicine consists of amusing the patient while nature cures the disease.” Charlie Gillihan was born and raised in Indiana and graduated from Columbia University with a degree in creative writing. After graduation he taught chemistry and other science courses for three years in the New York City public schools. He will graduate from New York University's School of Medicine in May 2019, and will continue his training in NYU's internal medicine residency. Charlie is fluent in Spanish, having spent considerable time in Central and South America, and his bilingualism is often useful in his clinical work. To see what he's up to, find him on Twitter.

Welcome to the first episode of The RecoverMe Podcast. Meet your host, Dr. Warren Wiley, an optimal health expert, as he talks about quicker, easier, and less stressful tips on how to take care of your body holistically.Warren will cover the basic philosophy of the RecoveryMe and how it helps people achieve optimal health, optimal fitness, optimal physique and optimal energy. Are you ready to change your life? EPISODE HIGHLIGHTS[02:54] I can't control your stresses, but I can help your body deal with them better.[05:23] How do I initiate change myself? [06:56] That's what the RecoverMe philosophy is to help you during the rest of your life, so when you do get exposed to stress, when you are exposed to toxins in the environment, when you do go too far too many holiday parties around between the month of Thanksgiving and Christmas, your body recovers and you're fine. You're unscathed from it. [08:52] I will teach how to allow your body to handle living this century.[10:33] The RecoverMe philosophy is beat it to the punch.[10:46] I want to teach you how to intervene now, right now.[13:14] Quality of life. That's what really matters. [17:12] Look up the medicine you're taking on the Internet and look at its NNT, Number Needed to Treat. [17:52] The new medicine, the medicine that really gave rise to the RecoverMe philosophy is actually based on quantum physics, quantum mechanics and quantum theory, and that is things are interrelated and that is you cannot remove the observer from the experiment. [21:13] Rather than just treating a number on paper with a drug, let's look at all the mediators around it and how they're influencing the person and how that influence can be optimized for a better quality life. [23:54] Mom was a diabetic, Dad was a diabetic, I'm going to be diabetic. There's no gene for diabetes. I tell them, however you grew up in their house, you learned how to eat like they do. You&

This week we talk with Charlie Wray, MD, Assistant Professor of Medicine at UCSF, about why clinicians should use social media in their professional lives. Charlie is a hospitalist and the Associate Social Media Editor for the Journal of Hospital Medicine. His arguments for using social media are germane to all clinicians, however. "Number Needed to Tweet" is the title of his recent grand rounds on this subject.

Show Notes Welcome to our latest installment of our [JC Series]! In this episode we cover THERAPY: Does a given intervention have a meaningful effect on patient outcomes?We also have some SISSoL (STATS IN 60 SECONDS OR LESS) topics cooking for you: Risk, Confidence Intervals and the Number Needed to Treat. Listen & take a look at our show notes for more information: Pulmcast.com

In this episode of Bedside Rounds, we discuss how risks and benefits are communicated by scientists and physicians, and why those numbers you see in advertisements and newspapers might not be the clearest way to express risk.

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Iain and Simon chat about how we can start to translate research findings in to natural frequency summaries that help clinicians and patients alike understand the value of therapeutic interventions. The NNT site we mention is just fantastic. Visit them here  Great revision page here by the amazing LITFL crew  The NNT for tranexamic acid is 67 not 50. S