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    • Dec 5, 2024 LATEST EPISODE
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    Parmita Mishra — How to Think About Biology (EP.244)

    Play Episode Listen Later Dec 5, 2024 90:55


    Infinite Loops Key Takeaways Finding novel ways to understand epigenetics will advance precision medicine by taking into health state beyond sequencing and coding The cell doesn't just work because it's affiliated with a phenotype – the environment and everything sitting on top of the cell play a huge role in our dynamic lifeAI and LLM can interact with other innovations to be able to accomplish much more in biology and medicine – we are at the beginning, not the end But we need much more understanding to feed models the right dataThe FDA is a health company, not a scientific company; their concern is whether something will harm you, not how to understand how it works The FDA paradigm needs to change to make real advances in biologyThe people writing the regulations don't have a deep understanding of the field they are regulating – they just want to be able to label something as non-lethalData collection goal to advance the field of biology: Reduce barriers to data collection so it doesn't involve the use of biopsy, tagging, staining, and leaves something unperturbedRead the full notes @ podcastnotes.orgParmita Mishra is a computational biologist and the founder & CEO of Precigenetics, a company aiming to become a rocket to precision medicine. Parmita is deeply knowledgeable about cutting-edge biology, particularly epigenetics — how behavior and environment can affect gene function without altering genetic code. Her passion for advancing our understanding of diseases is inspiring (and contagious: OSV is an investor in Parmita's company!) In our conversation, Parmita and I discuss everything from the curious case of male baldness to how her parents have saved 50,000 lives.  I hope you enjoy this conversation as much as I did. For the full transcript, highlights, and bucketloads of other goodies designed to make you go, “Hmm, that's interesting!”, check out our Substack. Important Links: LinkedIn Twitter Website Precigenetics Twitter Preciginetics launch post Show Notes: Explaining epigenetics to a golden retriever The curious case of male pattern baldness How to think about biology: start from first principles & beware binary thinking The lens you look through determines what you see The problem of data collection in biology Why the FDA needs to change its approach Why we still don't understand the human brain Garry Tan's advice: “Get an idea. Get a co-founder.” What's been surprising about foundership? Failure is a ladder Obsession & how Parmita's parents have saved 50,000 lives The most surprising things about America Parmita as World Empress Books Mentioned: What is Life?; by Erwin Schrodinger I should have loved biology; by James Somers Gödel, Escher, Bach: An Eternal Golden Braid; by Douglas Hofstadter The Hypomanic Edge: The Link Between (A Little) Craziness and (A Lot of) Success in America; by John D. Gartner

    $100B Founder Breaks Down The Biggest AI Business Opportunities For 2025

    Play Episode Listen Later Nov 30, 2024 91:38


    My First Million Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgEpisode 653: Shaan Puri ( https://x.com/ShaanVP ) talks to Furqan Rydhan ( https://x.com/FurqanR ) about the biggest opportunities in AI right now.  — Show Notes:  (0:00) Intro (4:42) Define the Job-to-be-done (8:20) How to build an AI Agent workflow (11:16) AI Tools break down (27:05) How Polymarket won (31:48) Why VR is a sleeping giant? (44:43) Be a lifelong player in tech (58:52) The unbeatable combination (1:02:27) Adam Foroughi's A+ execution (1:18:35) Betting on -1 to 0 — Links: • Furqan's site - https://furqan.sh/  • Founders, Inc - https://f.inc/  • Applovin - https://www.applovin.com/  • Claude - https://claude.ai/  • OpenAI - https://platform.openai.com/  • Langchain - https://www.langchain.com/  • AutoGen - https://autogenai.com/  • Crew - https://www.crewai.com/  • CloudSDK - https://cloud.google.com/sdk/  • Perplexity - https://www.perplexity.ai/  • “Attention is all you need” - https://typeset.io/papers/attention-is-all-you-need-1hodz0wcqb  • Anthropic - https://www.anthropic.com/  • Third Web - https://thirdweb.com/  • Luna's AI Brain - https://terminal.virtuals.io/  • Oasis - https://oasis.decart.ai/welcome  • Polymarket - https://polymarket.com/  • Gorilla Tag - https://www.gorillatagvr.com/  • Yeeps - https://tinyurl.com/59z2yrdu  — Check Out Shaan's Stuff: Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it's called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd — Check Out Sam's Stuff: • Hampton - https://www.joinhampton.com/ • Ideation Bootcamp - https://www.ideationbootcamp.co/ • Copy That - https://copythat.com • Hampton Wealth Survey - https://joinhampton.com/wealth • Sam's List - http://samslist.co/ My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

    #869 - Dry Creek Dewayne - Life Lessons From A Modern Cowboy

    Play Episode Listen Later Nov 28, 2024 114:51


    Modern Wisdom Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgDewayne Noel is a wrangler, cowboy, educator, and founder of Dry Creek Wrangler School. Hustle culture often tells us that working harder is the only way to succeed—grinding through 80-hour weeks on 4 hours of sleep per night. But what if the real solution isn't about working harder, but finding balance? What if true success lies in slowing down, savouring life, smoking a cigar on the porch occasionally and being fully present. How differently might we define success then? Expect to learn who Dry Creek Dewayne's is, his backstory and upbringing, how to un-harden yourself, how any person can overcome & control their anger, what Dewayne has learned from working with horses, the dangers of being out of balance in work & life, how to have a better relationship with the voice in your head, how to find the right partner & why men need to learn to treat women better, why bad fathers are partly to blame for the downfall of America's culture, what a day in the life of Dewayne's life is like and much more…. Sponsors: See discounts for all the products I use and recommend: https://chriswillx.com/deals Get a Free Gift, 5 Free Travel Packs, Free Liquid Vitamin D and more from AG1 at https://drinkag1.com/modernwisdom Get expert bloodwork analysis and bypass Function's 300,000-person waitlist at https://functionhealth.com/modernwisdom Get a Free Sample Pack of all LMNT Flavours with any purchase at https://drinklmnt.com/modernwisdom Get a 20% discount on Nomatic's amazing luggage at https://nomatic.com/modernwisdom Extra Stuff: Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices

    Tucker Carlson and Russ Vought Break Down DOGE and All of Trump's Cabinet Picks So Far

    Play Episode Listen Later Nov 24, 2024 116:45


    The Tucker Carlson Show Key Takeaways  When political leaders on the left say they want to “preserve democracy”, they are saying they want to preserve their amorphous oligarchy and administrative deep state Establishment opposition to the America First agenda is evidence that the DC think tanks are losing power and influence Three things President Trump should do to fix the root problems of government corruption:1. Remove independence from government agencies2. Bring back the notion of empowerment to fiscal spending 3. Restore at-will employment in federal agencies  Federal employees will perform better at their jobs if they realize they are not immune to accountability The average Republican cares more about the military-industrial complex than the woke and weaponized bureaucracy that torments American citizens; they care more about flexing their power abroad than they do about their own country The separation of powers philosophy is designed for high-conviction, opinionated leadership; it is conducive to a Donald Trump type of personality Read the full notes @ podcastnotes.orgRuss Vought ran OMB under Trump the first time, and hopefully will again. Here's what he learned about how the deep state actually works. (00:00) What is the Office of Management and Budget? (07:57) How Our Intel Agencies Overrule the President (34:21) What Will the Congressional Hearings Look Like for Trump's Appointees? (42:18) The Evil Think Tanks Trying to Undermine You (49:48) They're Trying to Leave Trump With WWIII (58:06) The Root Problem of Government Corruption PreBorn Save babies and souls https://PreBorn.com/Tucker Liberty Safe https://LibertySafe.com/Tucker Promo code “Tucker” PureTalk https://PureTalk.com/Tucker Get 50% off first month Alp Pouch Shop now at https://AlpPouch.com Learn more about your ad choices. Visit megaphone.fm/adchoices

    Unicorn Founder on Unseen Arbitrages, the Paradox of Wealth + Charlie Munger Wisdom ft. Ryan Petersen

    Play Episode Listen Later Nov 21, 2024 61:01


    My First Million Key Takeaways  Instead of focusing on how something might fail, consider how big the idea could be if everything worked out You don't always want to sit behind a defensive moat; sometimes, a high-velocity attack is the best way to win Mental models from one discipline are often applicable in another discipline; cross-pollinate ideas and concepts across disciplines and you may discover something novel The key to success is dumb competition; competing against knuckleheads increases your chances of successFocusing on making money will cause you to make less money; nobody wants to give money to people who are too focused on making money It is fine to want money, but wealth is a paradox; the more of it you want, the less of it you get It is better to focus on things that are upstream of making money, such as solving problems and developing skills that are valuable to other people The greatest returns in investing come from allowing the compounding machine to run; do not make decisions or engage in behavior that interrupts the compounding machine You have a massive arbitrage opportunity if you can avoid mimetic desire in venture capital investing In life and business, you can just do things! You don't always need permission Read the full notes @ podcastnotes.orgEpisode 648: Shaan Puri ( https://x.com/ShaanVP ) talks to Flexport founder Ryan Petersen ( https://x.com/typesfast ) about playing both games: bootstrapping a startup to millions and raising venture capital to build a multi-billion dollar company.  — Show Notes:  (0:00) Import Genius (5:36) Paul Graham's superpower (9:34) Data-as-a-service framework (13:51) Charlie Munger's worldly wisdom (19:45) Prioritizing adventure (24:09) The paradox of wealth (28:51) Charlie Munger's student experiment (31:00) Negotiation masterclass (37:23) Inside Founders Fund (43:16) Being in a crowd v following a crowd (46:29) Highs and lows (48:52) "You can just do things" (50:16) Unseen arbitrages (53:00) $50M Phone booths — Links: • Flexport - https://www.flexport.com/  • Flexport on X - https://x.com/flexport • ImportGenius - https://www.importgenius.com/  • Schlep Blindness - https://paulgraham.com/schlep.html • Poor Charlie's Almanack - https://www.stripe.press/poor-charlies-almanack  • Founders Fund - https://foundersfund.com/  — Check Out Shaan's Stuff: Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it's called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd — Check Out Sam's Stuff: • Hampton - https://www.joinhampton.com/ • Ideation Bootcamp - https://www.ideationbootcamp.co/ • Copy That - https://copythat.com • Hampton Wealth Survey - https://joinhampton.com/wealth • Sam's List - http://samslist.co/ My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

    Peter Thiel on Trump, Elon, and the Triumph of the Counter-Elites

    Play Episode Listen Later Nov 17, 2024 116:11


    Honestly with Bari Weiss ✓ Claim Key Takeaways  Prominent people are shifting to the right because they never signed up for the left's intellectual straight-jacketThe 2024 presidential election marked a collapse of liberalism and the Democratic Party; it is too narrow of thinking to blame it on a senile Biden or a goofy Kamala If the machine always wins, then you no longer have a democracy nor a democratic process: If Trump would have lost to the machine in 2024, who would have ever been able to defeat it?  If we are going to avoid World War III, we must learn the lessons of WWI and WWII; we cannot have excessive appeasement to dictators, but also, we cannot sleepwalk into armageddon On the elite Ivy League institutions: “Maybe they're good places for training conservatives. If you go to Yale Law School and you're one of five people in the class who are still conservative at the end, you'll be pretty good at understanding what's wrong with liberalism.” Populism and democracy may be a Russell conjugate: It is democracy when people vote the right way and it is populism when they vote the wrong wayBoth extreme dogmatism and extreme skepticism are incompatible with science If you make something into God, you make it into a scapegoat for all the problems too If you're addicted to the 140 characters on your shiny iPhone screen, you may not realize that the New York Subway and your decrepit apartment building are collapsing around you It matters what people do; there is room for human agency and human thought in the trajectory of the future Read the full notes @ podcastnotes.orgOn Tuesday night, president-elect Donald Trump announced that the richest man in the world, Elon Musk, along with entrepreneur Vivek Ramaswamy will head a new department in the Trump administration: the Department of Government Efficiency, or “DOGE.” Aside from the very strange fact that internet meme culture has now landed in the White House—Dogecoin is a memecoin—more importantly, what the announcement solidifies is the triumph of the counter-elite. A bunch of oddball outsiders ran against an insular band of out-of-touch elites supported by every celebrity in Hollywood—and they won. And they are about to reshape not just the government but also the culture in ways we can't imagine. And there was one person I wanted to discuss it with. He is the vanguard of those antiestablishment counter-elites: Peter Thiel. People describe the billionaire venture capitalist in very colorful terms. He's been called the most successful tech investor in the world. A political kingmaker. The bogeyman of the left. The center of gravity in Silicon Valley. There's the “Thielverse,” “Thielbucks,” and “Thielists.” To say he has an obsessive cult following would be an understatement. If you listened to my last conversation with Thiel a year and a half ago on Honestly, you'll remember that Peter was the first guy in Silicon Valley to publicly embrace Trump in 2016. That year, he gave a memorable speech at the RNC, and many in his orbit thought it was simply a step too far. He lost business at Y Combinator, the start-up incubator where he was a partner. Many prominent tech leaders criticized him publicly, like VC and Twitter investor Chris Sacca, who called Thiel's endorsement of Trump “one of the most dangerous things” he had ever seen.  Well, a lot has changed since then. For one, Thiel has taken a step back from politics—at least publicly. He didn't donate to Trump's 2024 campaign. There was no big RNC speech this year. But the bigger change is a cultural one. He's no longer the pariah of Silicon Valley for supporting Trump. On the surface, Thiel is someone who seems full of contradictions. He is a libertarian who has found common cause with nationalists and populists. He likes investing in companies that have the ability to become monopolies, and yet Trump's White House wants to break up Big Tech. He is a gay American immigrant, but he hates identity politics and the culture wars. He pays people to drop out of college, but, in this conversation at least, still seems to venerate the way that the Ivy Leagues are an indicator of intelligence. But perhaps that's the secret to his success: He's beholden to no tribe but himself, no ideology but his own. And why wouldn't you be when you make so many winning bets? From co-founding the e-payment behemoth PayPal and the data analytics firm Palantir (which was used to find Osama bin Laden) to being the first outside investor in Facebook, Thiel's investments—in companies like LinkedIn, Palantir, and SpaceX, to name a few—have paid off big time. His most recent bet—helping his mentee J.D. Vance get elected as senator and then on the Trump ticket as vice president—seems also to have paid off. The next four years will determine just how high Thiel's profit margin will be. Today: Thiel explains why so many of his peers have finally come around to Trump; why he thinks Kamala—and liberalism more broadly—lost the election; and why the Trump 2.0 team will be better than last time, with antiestablishment figures who are willing to rethink the system. We talk about the border, trade deals, student debt, Israel and foreign policy, the rise of historical revisionism, the blurry line between skepticism and conspiracy, and his contrarian ideas about what we might face in a dreaded World War III. If you liked what you heard from Honestly, the best way to support us is to go to TheFP.com and become a Free Press subscriber today. Learn more about your ad choices. Visit megaphone.fm/adchoices

    #863 - Matthew McConaughey - The Hidden Art Of Reinventing Yourself

    Play Episode Listen Later Nov 17, 2024 108:46


    Modern Wisdom Key Takeaways  Don't Half-Ass It: Think and try it out beforehand, but when it's time to go, dive in and finish it You should be able to laugh at the crisis; there is not always tribute in solemnity “Be very serious about your sense of humor.” – McConaughey Analyze the habits and behavior that engineer less pain in your life; you can't guarantee happiness, but there is a science to satisfaction  When things are going well, take time to reflect on why they may be going well so you can learn from your success and hopefully repeat those behaviors in the future In many ways, the things that you don't get help you find satisfaction in life more than the things that you do get Turn negativity into fuel: Rage, anger, and a thirst for revenge are mighty powerful emotions that can be used as activation energy in pursuit of a goal You have to pay a price to become a person that other people admire; while we all want to be relevant, we should consider what it is that we want to be relevant for Every decision has opportunity costs; choose pursuits that are worthy of the sacrifices that you will inevitably have to make “Life has to be lived forward, but it only makes sense in reverse.” – Søren KierkegaardRead the full notes @ podcastnotes.orgMatthew McConaughey is an Academy Award winning actor, a producer and an author. Expect to learn what “Don't half-ass it” means, the story of how Matthew got his iconic starting role in Dazed & Confused, how to see the upside during any crisis, why having a sense of humour should be your default emotion, McConaughey's own version of his Lonely Chapter, when you should listen to your gut versus your head, why McConaughey turned down $14.5M to pursue something great, Matthew's reflections on the 10 year anniversary of Interstellar, lesson on finding the perfect partner, and much more… Sponsors: See discounts for all the products I use and recommend: https://chriswillx.com/deals Get a 20% discount on your first order from Maui Nui Venison by going to https://mauinuivenison.com/modernwisdom (use code MODERNWISDOM) Sign up for a one-dollar-per-month trial period from Shopify at https://shopify.com/modernwisdom (automatically applied at checkout) Get a 25% discount on the best supplements from Momentous at https://livemomentous.com/modernwisdom (automatically applied at checkout) Shop SKIMS Mens at https://SKIMS.com/modernwisdom (automatically applied at checkout) Extra Stuff: Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices

    Why Carbon Dioxide Is So GOOD For You, How You Should *Really* Breathe, The New Science Of CO2 Therapy & More With Anders Olsson

    Play Episode Listen Later Nov 14, 2024 66:09


    Ben Greenfield Fitness Key Takeaways Carbon dioxide serves as the body's signal to take the next breath, not oxygenOxygen and carbon dioxide are like yin and yang: pH drops when CO2 goes up – when pH goes down, there's more oxygen delivered via hemoglobin into mitochondria The goal is to reduce respiratory rate so you can become more efficientYou can use different breathwork timing to manipulate your state: Inhale is tied to activation; exhale is for relaxation Use a longer exhale to relaxFast breathing is the hallmark of stress and hyperventilationCO2 therapies (like blood flow restriction) can also be used to increase muscle size by trapping more CO2 in working musclesCautions: When starting CO2 training start slow and listen to your body! Don't be discouraged if you don't notice improvements quickly, it can take some time to find the right dose for your bodyRead the full notes @ podcastnotes.orgCarbon dioxide therapy has become a highly debated and often misunderstood topic. Is elevated CO2 beneficial, or could it pose risks? What exactly are the advantages of CO2 therapy, and how might it impact your health? In this episode, you'll get to explore the transformative power of breathing with breathwork expert Anders Olsson. From the benefits of food-grade CO2 cylinders to advanced breathing techniques that can boost both mental and physical well-being, Anders shares invaluable insights. As the author of Conscious Breathing: Discover The Power Of Your Breath and creator of tools like the Relaxator and CarboHaler, he guides you through the profound impact breathwork has on emotions and stress management. You'll uncover the fascinating relationship between CO2 and oxygen delivery, the role of nitric oxide in respiratory health, and how specific breathing patterns can dramatically reduce stress and elevate overall health. Plus, you'll gain practical advice and discover cutting-edge research to enhance your daily breathwork practice. Anders Olsson is a breath coach, author, keynote speaker, inventor, and founder of the Conscious Breathing Institute. Anders joins me on the podcast to bring clarity to the benefits, potential concerns, and safe applications of CO₂ therapy. After living most of his life with a high inner stress and a racing mind, Anders was fortunate enough to come across tools that have helped him relax and find his inner calm. The most powerful of these tools has undoubtedly been to change his breathing habits, which made Anders decide to become the world's most prominent expert in breathing. That was 15 years ago, and since then, he has inspired hundreds of thousands of people to achieve better health and an improved quality of life. Anders is the author of the best-selling book Conscious Breathing: Discover The Power of Your Breath and the co-inventor of the Relaxator, Sleep Tape, CarboHaler, and BodyStream CO2 Bath. He is considered an authority on CO2 therapy and coaches high-level executives and elite athletes. In 2018, Anders facilitated and participated in a groundbreaking three-week breathing study at Stanford, highlighted in James Nestor's book Breath. Tune in and breathe easy as we unpack the science and art of effective breathing to help you reduce stress, boost energy, and enhance your overall well-being. Full show notes: BenGreenfieldLife.com/CO2podcast Episode Sponsors:  LVLUP Health: Head over to lvluphealth.com/BGL for a special discount on their game-changing range of products. Mimio: Visit mimiohealth.com/bgl and use code BGL20 to get 20% off your first order. Pendulum: Get 20% off your first month of any Pendulum probiotic with code GREENFIELD at PendulumLife.com/Greenfield. Ketone-IQ: Save 30% off your first subscription order of Ketone-IQ at Ketone.com/BENG.  Manukora: Head to manukora.com/ben or use code BEN for $25 off the Manukora Starter Kit.See omnystudio.com/listener for privacy information.

    Trump wins! How it happened and what's next

    Play Episode Listen Later Nov 10, 2024 103:28


    All-In with Chamath, Jason, Sacks & Friedberg Key Takeaways  The Trump win represents a dismissal of Wokeism and judgmentalism and is a ringing endorsement of meritocracy and common sense Donald Trump has increased his support across the electorate; except for two demographic groups (65+ and white college women), every single demographic group shifted towards Republican from 2020 to 2024 Comparing Trump votes from 2020 to 2024 in areas that are bastions of elitist liberal thinking:In California, Trump lost by 29 points in 2020; he lost by 17 points in 2024 In New York, Trump lost by 23 points in 2020; he lost by 12 in 2024 The current Democratic Party base consists of the elites: The overeducated, affluent, and non-religious types who are disconnected from the reality of most AmericansIf these people stay in control of the Democratic Party, the Republicans will probably have an electoral majority for the foreseeable future “I think that the Democrats will lose one of California or New York in the next eight years.” – Chamath “The legacy media spell is broken. Their credibility has been destroyed and I think that the repudiation of the legacy media is one of the most important  results of this election. It just shows that the Democrats had a trillion-dollar propaganda machine on their side and Trump was still able to win.” – David Sacks  Science is the constant process of questioning whether you are right or wrong; reasserting the scientific process of skepticism in federal agencies may help restore trust and faith in our institutions“In the most basic calculation, the bottom fell out of the Democratic Party.” – Chamath Donald Trump won because his focus is on solving real problems that are affecting Americans  “Americans love winners and innovation, and they hate socialism and woke nonsense – it's time for a hard reset.” – Jason Read the full notes @ podcastnotes.org(0:00) Bestie intros! (4:55) Sacks recaps election night at Mar-a-Lago (8:28) Analyzing the results: how Trump won, why Kamala and the Democratic Party lost (25:55) The failing Democratic coalition, campaign spend disparity, Trump's advantage in earned media (37:59) What mattered most: Policy, Candidate, or Campaign? (50:44) GOP will likely win House and Senate, potential cabinet positions, avoiding neocons (1:10:42) Cabinet positions, shaking up the unelected bureaucratic branch (1:28:47) California rejects progressives (1:35:17) Abortion laws being settled around the US Get tickets for The All-In Holiday Spectacular!: https://allin.ticketsauce.com/e/all-in-holiday-spectacular Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram: https://www.instagram.com/theallinpod Follow on TikTok: https://www.tiktok.com/@theallinpod Follow on LinkedIn: https://www.linkedin.com/company/allinpod Intro Music Credit: https://rb.gy/tppkzl https://x.com/yung_spielburg Intro Video Credit: https://x.com/TheZachEffect Referenced in the show: https://x.com/twobitidiot/status/1854192602985255042 https://www.270towin.com/2024-election-results-live/president https://x.com/ChrisCillizza/status/1854515791690953066 https://www.youtube.com/watch?v=_e8-KX3XKL8 https://x.com/Jason/status/1854209590424121464 https://x.com/SawyerMerritt/status/1854045298475110779 https://x.com/DavidSacks/status/1854342908356297068 https://x.com/arifleischer/status/1854270972775305291 https://www.fec.gov/data/spending-bythenumbers/?office=P https://www.usnews.com/news/national-news/articles/2024-11-01/16-billion-will-be-spent-in-the-2024-election-wheres-it-all-going https://x.com/DavidSacks/status/1829383729284067659 https://www.snopes.com/fact-check/trump-very-fine-people https://x.com/TheRabbitHole84/status/1840977783247286429 https://www.cnn.com/election/2024 https://polymarket.com/event/house-control-after-2024-election https://x.com/MarioNawfal/status/1854536321282519396 https://www.instagram.com/p/DCFJ4mlsmEG/?hl=en https://x.com/DavidSacks/status/1854202717637411199 https://www.scotusblog.com/2024/06/supreme-court-strikes-down-chevron-curtailing-power-of-federal-agencies https://x.com/chamath/status/1854229735477551600 https://www.nbcnews.com/politics/2024-election/la-district-attorney-progressive-loses-re-election-gascon-rcna175906 https://www.nytimes.com/interactive/2024/11/05/us/elections/results-abortion.html

    #1427 Howard Lutnick | Bitcoin & Tariffs Will Save The US Economy

    Play Episode Listen Later Nov 5, 2024 125:59


    Pomp Podcast Key Takeaways  The fundamental aspect of the American Dream is creating a better life for your kids than the one you livedTwo-thirds of the American workforce has a high school education, and only one-third has a college education; on average, a person with a college education lives seven years longer than a person without one “Right now, I am focused on: ‘What's the right move for America?' And that's why I'm all in with Donald Trump – his policies, his thinking, his way of just looking at things, his intuition. It's just right.” – Howard Lutnick In the past, the Democratic Party used to be the party for the workers, and the Republican Party was the party for businesses, but this has completely shiftedCoastal elite nonsense has infiltrated the Democratic Party; it no longer represents the working class as it once didInstead of taxing the hell out of the American people, what if the US government made money off tariffs when other countries bought our stuff?All of the fentanyl that makes its way into the US comes from China; something nefarious might be at play, given the damage this drug is doing to America's youth and working-class After the 9/11 attacks, Howard Lutnick pledged to forgo his salary and bonuses for several years to support the families of Cantor Fitzgerald employees who lost their lives“Everytime bitcoin dips, I'm going to be the buyer.” – Howard Lutnick He has “hundreds and hundreds of millions of dollars” worth of exposure to Bitcoin, and one day expects his stack to be worth billions “Bitcoin will be way way way higher, sometimes lower. You just have to have faith.” – Howard Lutnick    Read the full notes @ podcastnotes.orgHoward Lutnick is the CEO of Cantor Fitzgerald. Howard is one of the most interesting people in finance, he is a billionaire, and has incredible ideas to improve America. In this conversation, we talk about the national debt, inflation, why he is the co-head of the Trump transition team, what their plan is to balance the budget, how they are going to change things around economically, and a touching story about 9/11.  ======================= Buy book: https://www.amazon.com/Live-Extraordinary-Life-Anthony-Pompliano/dp/0857199927/ ======================= Gemini is the safe and secure way to trade crypto. Gemini is offering eligible new users the opportunity to earn $100 in BTC when they trade $1000 in crypto within their first 30 days of signing up. Head over to ⁠https://www.gemini.com/partners/pomp⁠ and start trading crypto to earn $100 in BTC. ======================= The Pomp Podcast is powered by BetOnline.ag, the premier crypto-friendly place to gamble on politics and sports, casino, poker and horse racing. BetOnline.ag gives you the ability to use Bitcoin and more than a dozen altcoins to make deposits and withdraw your winnings. There are no crypto transaction fees, and processing is instantaneous and secure. Visit ⁠⁠⁠⁠https://promotions.betonline.ag/pomp⁠⁠⁠⁠ and use PROMO CODE: POMP100 to receive a 100% matching bonus on any crypto deposit. BetOnline.ag is available in nearly every country around the world, making it the top global gaming destination for crypto users. ======================= Pomp writes a daily letter to over 265,000+ investors about business, technology, and finance. He breaks down complex topics into easy-to-understand language while sharing opinions on various aspects of each industry. You can subscribe at https://pomp.substack.com/ ======================= View 10k+ open startup jobs: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://dreamstartupjob.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Enroll in my Crypto Academy: https://www.thecryptoacademy.io/

    How Mike Posner built a music empire from his dorm room

    Play Episode Listen Later Nov 5, 2024 80:06


    My First Million Key Takeaways  Paradoxically, life gets easier when you choose to do hard things Have a goal that you can strive towards, but be cognizant of how you feel along the way in pursuit of that goal One of the hardest things in life is figuring out what you want “I think everybody should get rich and famous and do everything they ever dreamed of so they can see that it's not the answer.” – Jim Carey You have emotional sovereignty in how you choose to react to everything that happens in life; exercise and develop that sovereignty so that you can live the fullest life possible How Cheap is Your Happiness: Don't let the smallest inconvenience take you out of the beautiful state of being that is happiness“I just do what's cool to me, and sometimes the whole world agrees.” – Mike Posner Read the full notes @ podcastnotes.orgEpisode 640: Shaan Puri ( https://x.com/ShaanVP )sits down with Mike Posner ( https://x.com/MikePosner ) about his insane hustle, fame, loss and reinvention. — Show Notes:  (0:00) iTunesU Story (14:41) Going back to school, famous (21:40) Getting on the radio (26:40) “I just do what's cool to me and sometimes the whole world agrees” (30:06) One true sentence / Writing Process (39:50) Money, fame and Survivor (46:52) Advice to my younger self (48:10) Missed flight story (58:00) The making of a hit song (1:04:31) Walking Across America (1:11:09) "How cheap is your happiness?" (1:14:17) Beautiful States v Suffering States — Links: • Mike Posner - https://mikeposner.com/ — Check Out Shaan's Stuff: Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it's called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd — Check Out Sam's Stuff: • Hampton - https://www.joinhampton.com/ • Ideation Bootcamp - https://www.ideationbootcamp.co/ • Copy That - https://copythat.com • Hampton Wealth Survey - https://joinhampton.com/wealth • Sam's List - http://samslist.co/ My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

    How AI Will Transform Medicine, Entertainment, and Your Everyday Life | Marc Andreessen - PT 1

    Play Episode Listen Later Oct 31, 2024 70:35


    Impact Theory with Tom Bilyeu Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgIn this thought-provoking episode of Impact Theory with Tom Bilyeu, Tom sits down with tech visionary Mark Andreessen for an insightful discussion on the evolving role of technology in shaping our future. From the promise of AI and robotics to the pivotal lessons from historical economic changes, Mark argues that today's children will live better lives than their parents, thanks to technological advancements. Together, they delve into the implications of slow and rapid technology adoption across various sectors, highlighting how healthcare, education, and housing can benefit from embracing innovation. They explore the inefficiencies plaguing large corporations and juxtapose them with the rapid, iterative methodologies championed by leaders like Elon Musk. Mark offers a nuanced perspective on America's unique dynamism, driven by its people and less stifled by regulation compared to Europe. He and Tom also dive into the potential societal conflicts arising from AI, the nuances of free speech in the digital age, and the ever-present need for productivity growth. SHOWNOTES 00:00 Pre-meeting tech check with Tom planned. 31:34 Robotics' societal impact: automation and breakthroughs emerging. 39:30 Voice AI now enables engaging human-like interactions. 47:13 AI usage is widespread, impacting work and education. 57:54 Technology enhances material comfort, aids existential exploration. 01:05:27 Religion is now independent from genetics and location. CHECK OUT OUR SPONSORS Range Rover: Explore the Range Rover Sport at  https://landroverUSA.com Miro: Bring your teams to Miro's revolutionary Innovation Workspace and be faster from idea to outcome at https://miro.com. Netsuite: Download the CFO's Guide to AI and Machine Learning for free at https://netsuite.com/theory Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impact Momentous: Shop now at https://livemomentous.com and use code IMPACT for 20% your new Momentous routine. FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu What's up, everybody? It's Tom Bilyeu here. If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu's Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you. LISTEN AD FREE + BONUS EPISODES on APPLE PODCASTS: apple.co/impacttheory Learn more about your ad choices. Visit megaphone.fm/adchoices

    428: The True Dangers of Industrial Additives in Our Water and Food Supply | Yvonne Burkart, PhD

    Play Episode Listen Later Oct 31, 2024 79:43


    Genius Life Dr. Yvonne Burkart is a board-certified toxicologist with over 15 years of experience specializing in environmental health, chemical safety, and human health risk assessment. 15 Daily Steps to Lose Weight and Prevent Disease PDF: https://bit.ly/46XTn8f - Get my FREE eBook now! Subscribe to The Genius Life on YouTube! - http://youtube.com/maxlugavere Watch my new documentary Little Empty Boxes - http://littleemptyboxes.com This episode is proudly sponsored by: Puori provides IFOS-certified, high potency fish oil to satisfy all of your pre-formed omega-3 needs! Visit Puori.com/MAX and use promo code MAX to get 20% off site-wide. Manukora makes delicious, creamy, glyphosate-free Manuka honey that's rich in MGO. Head to http://manukora.com/genius for $25 off a starter Kit, which comes with an MGO 850+ Manuka Honey jar, 5 honey travel sticks, a wooden spoon, and a guidebook! LifeForce is a powerful, at-home biomarker testing solution (they test important biomarkers like ApoB, LDL, A1C, hormones, and more!). Head to MyLifeForce.com and use code GENIUS for 15% off. 

    #323 - CRISPR and the future of gene editing: scientific advances, genetic therapies, disease treatment potential, and ethical considerations | Feng Zhang, Ph.D.

    Play Episode Listen Later Oct 30, 2024 125:40


    Drive with Dr. Peter Attia Key Takeaways The human genome was sequenced 25 years ago, what's the delay in editing? We know the sequence of the genes but we don't know what most of the genes do, nor do we fully understand the coding and non-coding sequence (yet)CRISPR is an adaptive immune system: After the first infection, the bacteria has been ‘vaccinated' against the virus The next time the virus comes around, it will inject its genetic information into the bacteria but now the bacteria in the CRISPR area have a signature of the virusDifficulties in application of CRISPR: CRISPR uses a guide RNA to recognize the virus DNA but delivery of the Cas + guide RNA needs to be precise and the protein is too large to insert with ease But, solving the delivery issue doesn't mean CRISPR is suitable for all diseases; its most potent application is for genetic mutations (and likely not cancer which has many different mutations in the cell)Future goals of CRISPR technology: Creating more feasible Cas and guide RNA delivery system; inserting large genes into the genome, precisely and efficientlyEthical considerations of gene editing germline: Slippery slope argument: If we allow X and Y, we will enter an unchartered territory with designer babies, making babies smarter (which we don't know how to do), etc. It's worth noting that athletics, and intelligence, are more complicated than we want to believe; even with the right genetics, environment plays a huge role in realizing genesThinking about how the line should be drawn: Is there an obvious and important medical benefit?Read the full notes @ podcastnotes.org View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Feng Zhang, a professor of neuroscience at MIT and a pioneering figure in gene editing, joins Peter to discuss his groundbreaking work in CRISPR technology, as well as his early contributions to optogenetics. In this episode, they explore the origins of CRISPR and the revolutionary advancements that have transformed the field of gene editing. Feng delves into the practical applications of CRISPR for treating genetic diseases, the importance of delivery methods, and the current successes and challenges in targeting cells specific tissues such as those in the liver and eye. He also covers the ethical implications of gene editing, including the debate around germline modification, as well as reflections on Feng's personal journey, the impact of mentorship, and the future potential of genetic medicine. We discuss: Feng's background, experience in developing optogenetics, and his shift toward improving gene-editing technologies [2:45]; The discovery of CRISPR in bacterial DNA and the realization that these sequences could be harnessed for gene editing [10:45]; How the CRISPR system fights off viral infections and the role of the Cas9 enzyme and PAM sequence [21:00]; The limitations of earlier gene-editing technologies prior to CRISPR [28:15]; How CRISPR revolutionized the field of gene editing, potential applications, and ongoing challenges [36:45]; CRISPR's potential in treating genetic diseases and the challenges of effective delivery [48:00]; How CRISPR is used to treat sickle cell anemia [53:15]; Gene editing with base editing, the role of AI in protein engineering, and challenges of delivery to the right cells [1:00:15]; How CRISPR is advancing scientific research by fast-tracking the development of transgenic mice [1:06:45]; Advantages of Cas13's ability to direct CRISPR to cleave RNA and the advances and remaining challenges of delivery [1:11:00]; CRISPR-Cas9: therapeutic applications in the liver and the eye [1:19:45]; The ethical implications of gene editing, the debate around germline modification, regulation, and more [1:30:45]; Genetic engineering to enhance human traits: challenges, trade-offs, and ethical concerns [1:40:45]; Feng's early life, the influence of the American education system, and the critical role teachers played in shaping his desire to explore gene-editing technology [1:46:00]; Feng's optimism about the trajectory of science [1:58:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

    #855 - Richard Reeves - Why Do Modern Men Feel So Left Behind?

    Play Episode Listen Later Oct 27, 2024 177:41


    Modern Wisdom Key Takeaways  Now more than ever,young men are uncertain about what the world needs from themThe increase in young male suicide may be due to men retreating from the difficulties and challenges of modern society “The state of feeling unneeded is literally fatal.” – Richard Reeves Four out of five teens who commit suicide are boys: Across every age group, the suicide rate is 4x higher amongst men than women There has been an expansion in the domains of neediness for women and a contraction in the domain of neediness for men The mental health field is more female-friendly than male-friendly; the whole field of mental health has been coded as female and feminine – and we wonder why men are not interested in it!  Young men feel politically homeless, and they especially do not feel welcomed by the political left; instead of turning to the left or the right, younger men tend to retreat Recently, there has been a massive increase in drug poisoning deaths among young men From 2001 to today in the United States, the increase in deaths from drug poisoning is equivalent to an additional 400,000 menIn the US, only half of men in their 30s and 40s without a college degree are in a household with childrenFor men, the old form of neediness as a protector has been significantly evacuated and replaced by nothing The best protector against despair is realizing that the world needs you Read the full notes @ podcastnotes.orgRichard Reeves is a writer, researcher and the Founder of the American Institute for Boys & Men. Men have been struggling for a long time. What exactly is going on? What resources can genuinely help modern men, and how can we better understand the dynamics that are driving this decline in male wellbeing. Expect to learn why Obama endorsed Richard's book, the scary trends about male suicide, why it's important for humans to feel needed, whether the Harris-Walz campaign has even considered men's existence, if this upcoming election will be decided by masculinity, Richard's thoughts on therapy for men and much more…. Sponsors: See discounts for all the products I use and recommend: https://chriswillx.com/deals Get 50% off your first Factor Meals box at https://factormeals.com/MW50 (automatically applied at checkout) Get expert bloodwork analysis and bypass Function's 300,000-person waitlist at https://functionhealth.com/modernwisdom (automatically applied at checkout) Get a 20% discount on your first order from Maui Nui Venison by going to https://mauinuivenison.com/modernwisdom (use code MODERNWISDOM) Get a 20% discount on the best supplements from Momentous at https://livemomentous.com/modernwisdom (automatically applied at checkout) Extra Stuff: Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices

    430: How to Reclaim Your Health From a Broken Medical System | Marty Makary, MD

    Play Episode Listen Later Oct 26, 2024 95:38


    Genius Life Key Takeaways In medicine (and everywhere), there is resistance to new ideas – so many people have spent so much time holding a certain belief, that the cost is too high to changeThe distrust in science and medicine is because there is no humility in walking back incorrect informationWe need people who are willing to speak up instead of falling in line; science is the study of challenging deeply held assumptionsWe need new frontiers of medicine, people are hungry for answersThe future of medicine is hopeful as the new generation of medical students and doctors is not on board with the traditional path of doing whatever you need to secure NIH funding and falling in line It's time we consider NIH term limitsWe spend more money on pharmaceuticals than we do on understanding the origins of diseaseNew formula for medicine: (1) Invite dissenting opinions; (2) Create a culture of speaking up; (3) Recognize that we all have biases and suspend those biases as we hear new informationRead the full notes @ podcastnotes.orgMarty Makary, MD is a Johns Hopkins professor and member of the National Academy of Medicine. He is the author of Blind Spots: When Medicine Gets It Wrong, and What It Means for Our Health. 15 Daily Steps to Lose Weight and Prevent Disease PDF: https://bit.ly/46XTn8f - Get my FREE eBook now! Subscribe to The Genius Life on YouTube! - http://youtube.com/maxlugavere Watch my new documentary Little Empty Boxes - http://littleemptyboxes.com This episode is proudly sponsored by: Birch Living makes organic, hypoallergenic, offgassing-free mattresses that are super comfy to radically improve your sleep. Head to http://birchliving.com/genius and use code GENIUS for 25% off all mattresses! BUBS Naturals makes my favorite collagen, pure and unflavored, perfect for mixing into any drink, soup, or even recipes! Your hair, skin, and nails will thank you. Visit BUBSNaturals.com and use code GENIUS for 20% off. Puori provides IFOS-certified, high potency fish oil to satisfy all of your pre-formed omega-3 needs! Visit Puori.com/MAX and use promo code MAX to get 20% off site-wide.

    605: Seth Godin - How To Be Remarkable, Create a Strategy, Build a Tribe, Develop Taste, Lead Others, & Leave a Dent in The World

    Play Episode Listen Later Oct 26, 2024 53:35


    Learning Leader Show Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgThe Learning Leader Show With Ryan Hawk Full show notes at www.LearningLeader.com My books: Welcome to Management - https://amzn.to/3XWyZAH  The Pursuit of Excellence - https://amzn.to/4eX9vtP  The Score That Matters - https://amzn.to/3zPub7Z  Seth Godin is the author of 21 international bestsellers that have changed the way people think about work and art. They have been translated into 38 languages. His breakthrough books include Purple Cow, Tribes, The Dip, Linchpin, and his latest book is called This is Strategy. He writes one of the most popular daily blogs in the world and has given 5 TED talks. He is the founder of the altMBA, and the former VP of Direct Marketing at Yahoo! Notes: "If you want word of mouth, you have to create something remarkable, and that means it's worthy of remark." The elegant path is the most useful way forward. “My neighbor is a barefoot runner. He glides without apparent effort.” Elegance is simplicity, efficiency, and effectiveness. Dorothy and Her Crew. How did Dorothy persuade the Lion, Tin Man, and Scarecrow to join her on the trip to see the Wizard? Did she make a case about how much she missed home? No. She created the conditions where the others could get what they wanted by joining her. Seeing Strategy Clearly. Strategy is a flexible plan that guides us as we seek to create a change. It helps us make decisions over time while working within a system. Low-Hanging Fruit Isn't. It's all been picked. The easy, direct, obvious paths are unlikely to get you the results you're working so hard to obtain. In fact, these paths are probably a trap. Seth, at one point, got 800 rejection letters. Have to keep going... "I wouldn't call Steve Ballmer a good leader." An example of Seth making a difference... He went to Kenya and talked with 60 people who started a book club based on his book Linchpin. "They decided to be leaders." Make decisions in the moment: Examine the issue Get feedback Look for patterns "Taste is knowing what the market wants before it knows it." Rick Rubin Reality distortion field Johnny Cash "What do you think?" "Objections are your friends." What are the commonalities among leaders with whom Seth has worked and who have sustained excellence? They are all different, but the one thing they have in common is they all have chosen to be leaders. And that means that they are here to make a change happen. Management doesn't just exist. It was invented. When you race to the bottom, You see people as resources, not as people. Questions That Lead To Strategies. 84 questions. They'll force you to think through your strategy. By answering them, you'll be better prepared to make a difference… And make a ruckus. Some of them: Who is this project for? What is my timeline? What systems would need to change for my project to succeed? Where will I cause tension? What resistance should I anticipate? Where is the empathy? What asset would transform my project? What can I learn from comparable projects? Is the change I'm making contagious? Can I make it easier for others to decide? How can I design for network effects? What are common objections I expect to encounter?

    Edwin Land and Steve Jobs

    Play Episode Listen Later Oct 26, 2024 62:18


    Founders ✓ Claim Key Takeaways  “If Steve Jobs studied Edwin Land, I think every other founder should as well.” – David Senra Optimize for breadth as well as depth; hire the chemist who does photography on the side! Something magical exists at the intersection of the humanities and the sciences “Missionaries make better products.” – Jeff Bezos Missionaries and mercenaries are the two types of people that will be attracted to a companyWhile the mercenaries are there for the perks, status, and money, the missionaries are there to make better products because they believe in what the company is doingLeverage the power of demonstration: No argument in the world can compare with one dramatic demonstrationA first-class product needs first-class packaging and marketing! The founder is the guardian of the company's soul If you are lucky enough to find your life's work, why would you quit? You should take yourself seriously, but don't make yourself miserable; none of us get out of this alive Read the full notes @ podcastnotes.orgWhat I learned from rereading Instant: The Story of Polaroid by Christopher Bonanos. ----Ramp gives you everything you need to control spend, watch your costs, and optimize your financial operations —all on a single platform. Make history's greatest entrepreneurs proud by going to Ramp and learning how they can help your business control your costs and save more. ----Founders Notes gives you the superpower to learn from history's greatest entrepreneurs on demand. You can search all my notes and highlights from every book I've ever read for the podcast. Get access to Founders Notes here. ----Join my free email newsletter to get my top 10 highlights from every book----Episode Outline: — The most obvious parallel is to Apple Computer. Both companies specialized in relentless, obsessive refinement of their technologies. Both were established close to great research universities to attract talent. Both fetishized superior, elegant, covetable product design. And both companies exploded in size and wealth under an in-house visionary-godhead-inventor-genius. At Apple, that man was Steve Jobs. At Polaroid, the genius was Edwin Land. Just as Apple stories almost all lead back to Jobs, Polaroid lore always seems to focus on Land.— Both men were college dropouts; both became as rich as anyone could ever wish to be; and both insisted that their inventions would change the fundamental nature of human interaction.— Jobs expressed his deep admiration for Edwin Land. He called him a national treasure.— Books on Edwin Land:Land's Polaroid: A Company and the Man Who Invented It by Peter C. Wensberg (Founders #263)A Triumph of Genius: Edwin Land, Polaroid, and the Kodak Patent War by Ronald Fierstein (Founders #134)Land's Polaroid: A Company and the Man Who Invented It by Peter C. Wensberg (Founders #133)The Instant Image: Edwin Land and the Polaroid Experience by Mark Olshaker (Founders #132)Insisting On The Impossible: The Life of Edwin Land and Instant: The Story of Polaroid(Founders #40)— Biography about Steve Jobs: Becoming Steve Jobs: The Evolution of a Reckless Upstart into a Visionary Leader by Brent Schlender and Rick Tetzeli— Edwin Land of Polaroid talked about the intersection of the humanities and science. I like that intersection. There's something magical about that place. There are a lot of people innovating, and that's not the main distinction of my career. The reason Apple resonates with people is that there's a deep current of humanity in our innovation. I think great artists and great engineers are similar, in that they both have a  desire to express themselves. In fact some of the best people working on the original Mac were poets and musicians on the side. In the seventies computers became a way for people to express their creativity. Great artists like Leonardo da Vinci and Michelangelo were also great at science. Michelangelo knew a lot about how to quarry stone, not just how to be a sculptor. —  Steve Jobs: The Exclusive Biography by Walter Isaacson (Founders #214)— Book on Henry Ford:I Invented the Modern Age: The Rise of Henry Ford by Richard Snow (Founders #9)The Autobiography of Henry Ford by Henry Ford (Founders #26) Today and Tomorrow Henry Ford (Founders #80) My Forty Years With Ford by Charles Sorensen  (Founders #118)The Story of Henry Ford and Thomas Edison's Ten Year Road Trip by Jeff Guinn (Founders #190) — Another parallel to Jobs: Land's control over his company was nearly absolute, and he exercised it to a degree that was compelling and sometimes exhausting.— When you read a biography of Edwin land you see an incredibly smart, gifted, driven, focused person endure decade after decade of struggle. And more importantly —finally work his way through.— Another parallel to Jobs: You may be noticing that none of this has anything to do with instant photography. Polarizers rather than pictures would define the first two decades of lands intellectual life and would establish his company. Instant photos were an idea that came later on, a secondary business around which his company was completely recreated.— “Missionaries make better products.” —Jeff Bezos— His letter to shareholders gradually became a particularly dramatic showcase for his language and his thinking. These letters-really more like personal mission statements-are thoughtful and compact, and just eccentric enough to be completely engaging. Instead of discussing earnings and growth they laid out Land's World inviting everyone to join.— Land gave him a four-word job description: "Keeper of the language.”— No argument in the world can ever compare with one dramatic demonstration. — My Life in Advertising by Claude Hopkins (Founders #170)— The leap to Polaroid was like replacing a messenger on horseback with your first telephone.— Hire a paid critic:Norio Ohga, who had been a vocal arts student at the Tokyo University of Arts when he saw our first audio tape recorder back in 1950. I had had my eye on him for all those years because of his bold criticism of our first machine.He was a great champion of the tape recorder, but he was severe with us because he didn't think our early machine was good enough. It had too much wow and flutter, he said. He was right, of course; our first machine was rather primitive. We invited him to be a paid critic even while he was still in school. His ideas were very challenging. He said then, "A ballet dancer needs a mirror to perfect her style, her technique.— Made in Japan: Akio Morita and Sony by Akio Morita.— Another parallel to Jobs: Don't kid yourself. Polaroid is a one man company.— He argued there was no reason that well-designed, wellmade computers couldn't command the same market share and margins as a luxury automobile.A BMW might get you to where you are going in the same way as a Chevy that costs half the price, but there will always be those who will pay for the better ride in the sexier car. Rather than competing with commodity PC makers like Dell, Compaq and Gateway, why not make only first-class products with high margins so that Apple could continue to develop even better first-class products?The company could make much bigger profits from selling a $3,000 machine rather than a $500 machine, even if they sold fewer of them.Why not, then, just concentrate on making the best $3,000 machines around? — Jony Ive: The Genius Behind Apple's Greatest Products by Leander Kahney.— How To Turn Down A Billion Dollars: The Snapchat Story by Billy Gallagher — Books on Enzo FerrariGo Like Hell: Ford, Ferrari, and Their Battle for Speed and Glory at Le Mans by A.J. Baime. (Founders #97) Enzo Ferrari: Power, Politics, and The Making of an Automotive Empire by Luca Dal Monte (Founders #98) Enzo Ferrari: The Man and The Machine by Brock Yates (Founders #220) — Soul in the game. Listen to how Edwin Land describes his product:We would not have known and have only just learned that a new kind of relationship between people in groups is brought into being by SX-70 when the members of a group are photographing and being photographed and sharing the photographs: it turns out that buried within us—there is latent interest in each other; there is tenderness, curiosity, excitement, affection, companionability and humor; it turns out, in this cold world where man grows distant from man,and even lovers can reach each other only briefly, that we have a yen for and a primordial competence for a quiet good-humored delight in each other:we have a prehistoric tribal competence for a non-physical, non-emotional, non-sexual satisfaction in being partners in the lonely exploration of a once empty planet.—  “Over the very long term, history shows that the chances of any business surviving in a manner agreeable to a company's owners are slim at best.” —Charlie Munger----“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — GarethBe like Gareth. Buy a book: All the books featured on Founders Podcast 

    Tom Holland Is More Than Spider-Man: On Living Alcohol-Free, Acting With Authenticity, & Launching A Second Career

    Play Episode Listen Later Oct 21, 2024 108:47


    Rich Roll Podcast Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgTom Holland is the star of Spider-Man, a nascent entrepreneur, and one of Hollywood's most grounded young actors. This conversation traverses the nexus of fame, personal growth, and Tom's journey toward sobriety, which catalyzed his foray into the non-alcoholic beverage industry. We explore his evolution from child actor to global superstar, his therapeutic relationship with golf, and how he's remained attuned to his authentic self amidst Hollywood's gilded chaos. Tom candidly reflects on navigating the intricacies of the Marvel Cinematic Universe and his recent return to the verité of Shakespearean theatre. Tom's infectious enthusiasm is palpable. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today's Sponsors:  Bon Charge: Use code RICHROLL to save 15% OFF

    Money CAN Buy Happiness (If You Use It In These Ways)

    Play Episode Listen Later Oct 18, 2024 47:38


    Art of Manliness Money can't buy happiness. It sounds good as a bumper sticker platitude.But the truth is, money can buy happiness. At least sometimes. In certain circumstances. If we view it and use it in the right ways.Here to unpack the conditions under which money can buy happiness and facilitate our flourishing is Dr. Daniel Crosby, a psychologist and behavioral finance expert and the author of The Soul of Wealth: 50 Reflections on Money and Meaning. Today on the show, Daniel shares the minimum income level at which money buys happiness, at least in the sense of avoiding pain. We talk about how to purchase material things in a way that increases happiness, while avoiding materialism, and the value of using your money to buy health and freedom. And we discuss the importance of finding an overarching why that guides the way you allocate your money and doing a values audit to see if your purpose and spending habits are aligned.Resources Related to the PodcastDaniel's previous appearances on the AoM podcast:Episode #222: The Laws of WealthEpisode #511: Mastering the Psychology of InvestingAoM Podcast #659: Do You Want to Be Rich or Wealthy? (And Why the Difference Matters)AoM Podcast #321: How to Think About Money"Experiences Won't Make You Happier Than Possessions"Die with Zero by Bill PerkinsConnect With Daniel CrosbyDaniel on XDaniel's podcast, Standard DeviationsDaniel on LinkedIn

    The Doctor Appointments & Lab Tests That Could Save Your Life | Dr. Mark Hyman

    Play Episode Listen Later Oct 18, 2024 34:37


    Doctor's Farmacy with Mark Hyman, MD Key Takeaways The benefits of conventional medicine for surgical intervention, emergencies, and palliative care can't be understated but the field falls short in identifying the root cause of illness and taking preventive actionAppointments no one should skip: Annual check-up with primary care doctor, colonoscopy Your annual checkup may seem futile and outdated but some tests are better than no tests to establish a baselineColon cancer is preventable and treatableAppointments men should not skip: Prostate examAppointments women should not skip: Gynecological exam & mammogramsRead the full notes @ podcastnotes.orgAre you up to date on the doctor appointments that could save your life? In this episode, I dive into the essential screenings you can't afford to skip, from mammograms and colonoscopies to functional lab tests that reveal much more than standard checkups. We'll break down how conventional medicine is great for emergency care and early detection, but it often misses the root causes of illness. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman's Weekly Longevity Journal This episode is brought to you by AG1 and Essentia. Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order. Visit myessentia.com/drmarkhyman and use code HYMAN for $100 off your mattress purchase Learn more about your ad choices. Visit megaphone.fm/adchoices

    #367 Inside the Contrarian Mind of Sam Zell

    Play Episode Listen Later Oct 16, 2024 50:06


    Founders ✓ Claim Key Takeaways  Some failure is inevitable; learn from it, do not beat yourself up over it, and keep moving forwardBusiness is not a battle to be waged; it is a puzzle to be solved True entrepreneurs never fail; sometimes the business venture doesn't work out for them, but they never fail Go to where it is less crowded; there is no substitute for limited competition Be someone that people make money with Have a long-term view and do not sacrifice your ability to do future deals by burning bridges to close the current one If you love what you do, then you will get really good at it and do it for a long time;money will come as a resultThe true test of an entrepreneur is someone who spends his life constantly testing his limits “Fear and courage are cousins – and very closely related.” – Sam Zell Read the full notes @ podcastnotes.orgWhat I learned from reading Money Talks, Bullsh*t Walks: Inside the Contrarian Mind of Billionaire Mogul Sam Zell by Ben Johnson.----Ramp gives you everything you need to control spend, watch your costs, and optimize your financial operations —all on a single platform. Make history's greatest entrepreneurs proud by going to Ramp and learning how they can help your business control your costs and save more. ----Founders Notes gives you the superpower to learn from history's greatest entrepreneurs on demand. You can search all my notes and highlights from every book I've ever read for the podcast. Get access to Founders Notes here. ----Join my free email newsletter to get my top 10 highlights from every book----Follow Founders Podcast on YouTube (Video coming soon!) ----“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — GarethBe like Gareth. Buy a book: All the books featured on Founders Podcast

    #448 – Jordan Peterson: Nietzsche, Hitler, God, Psychopathy, Suffering & Meaning

    Play Episode Listen Later Oct 13, 2024 150:11


    Artificial Intelligence Podcast Key Takeaways  The soul is the battleground between the forces of good and evil; it is your moral duty to constrain evil within yourself Communism does not scale and it does not iterate – whereas religious thought is the record of those ideas that have scaled and iterated  If you follow the voice of adventure and make the necessary sacrifices to follow the path that takes you out of your comfort zone, then you will experience the following benefits:Your life will be a blessing Everyone will hold you in high esteem You will establish something of permanent value You will do these things in a way that is maximally beneficial to everyone elseThere is no distinction between the truest adventure of life and taking on the maximal responsibility and burdenCompare yourself to who you were yesterday, not to who someone else is today Make the presumption that if you move forward in good faith, whatever happens to you will be the best thing that could happen – no matter what it is  Men should have a temper, but they should be able to regulate it; most of what passes for morality is nothing but cowardiceA good man has to be formidable: The capacity that could be the most potent force for evil can also be the most powerful force for good Welcome the adversity of life as a redemptive challenge; the best parts of yourself activate when you voluntarily contend with challengesAfter you go through a period of pain, you will have more gratitude for the ordinariness of life We have an existential moral duty to aim upward and to tell the truth Read the full notes @ podcastnotes.orgJordan Peterson is a psychologist, author, lecturer, and podcast host. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep448-sc See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: https://lexfridman.com/jordan-peterson-2-transcript CONTACT LEX: Feedback - give feedback to Lex: https://lexfridman.com/survey AMA - submit questions, videos or call-in: https://lexfridman.com/ama Hiring - join our team: https://lexfridman.com/hiring Other - other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: Peterson Academy: https://petersonacademy.com Jordan's X: https://x.com/jordanbpeterson Jordan's YouTube: https://www.youtube.com/@JordanBPeterson Jordan's Website: https://jordanbpeterson.com Jordan's Books: We Who Wrestle with God: https://amzn.to/485Dz4a Beyond Order: https://amzn.to/3T4LRBw 12 Rules for Life: https://amzn.to/3c4sqYF Maps of Meaning: https://amzn.to/3A1Ods2 SPONSORS: To support this podcast, check out our sponsors & get discounts: Eight Sleep: Temp-controlled smart mattress. Go to https://eightsleep.com/lex Ground News: Unbiased news source. Go to https://groundnews.com/lex BetterHelp: Online therapy and counseling. Go to https://betterhelp.com/lex LMNT: Zero-sugar electrolyte drink mix. Go to https://drinkLMNT.com/lex OUTLINE: (00:00) - Introduction (07:07) - Nietzsche (14:48) - Power and propaganda (19:54) - Nazism (24:54) - Religion (41:18) - Communism (47:03) - Hero myth (49:12) - Belief in God (59:24) - Advice for young people (1:12:02) - Sex (1:32:00) - Good and evil (1:44:46) - Psychopathy (1:58:15) - Hardship (2:10:31) - Pain and gratitude (2:21:32) - Truth PODCAST LINKS: - Podcast Website: https://lexfridman.com/podcast - Apple Podcasts: https://apple.co/2lwqZIr - Spotify: https://spoti.fi/2nEwCF8 - RSS: https://lexfridman.com/feed/podcast/ - Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 - Clips Channel: https://www.youtube.com/lexclips

    Glyphosate & Corruption In American Food 101 | @Realfoodology Courtney Swan

    Play Episode Listen Later Oct 13, 2024 72:03


    Culture Apothecary with Alex Clark Key Takeaways  Understanding Big Food: Ten companies own the entity of our food system – these companies have outsized control over our food system, and they care more about profits than human healthOur ancestors would not recognize the “foods” that we eat today; most people do not realize that new ingredients have been snuck into our food supply over the last fifty yearsFollowing World War II, in search of a new market, the chemical companies shifted their focus towards American farmlands and launched a new war on the bugs and pests on American farmlandsThe World Health Organization classifies glyphosate as a known carcinogen, and yet, approximately 280 billion pounds of glyphosate are sprayed on American crops per year; about 80-90% of grain products on grocery store shelves contain very high levels of glyphosate Companies such as Bayer make the chemicals that destroy our soil and give us cancer, then also produce and profit from drugs designed to treat those cancers Studies that go against the interests of the agrochemical companies are rare because those same chemical companies fund the majority of the research in the industry The way that we are farming now is not sustainable; if we continue down our current path of spraying all these chemicals on our food and destroying the soil, then we will only have 55 years of harvests left before plantable soil is gone The fruits and vegetables in the grocery store are losing vitamin and mineral content because the soil they were harvested in is not as healthy as it once wasApproximately 77% of adults between the ages of 17 and 24 are ineligible for military service due to obesity Tips from Courtney Swan: Buy organic, buy local produce from nearby farmers, form a relationship with a local rancher, shop the perimeter of the grocery store, buy real foods with simple ingredients, prioritize protein, and eliminate ultra-processed foodsRead the full notes @ podcastnotes.orgAn integrative nutritionist on a mission to change how America eats, Courtney Swan (aka @realfoodology on Instagram and host of the podcast of the same name) educates Alex on glyphosate, GMOs, how to start shopping for real food, and why parents need to choose between wellness and illness for their kids. Thank you to our sponsors! Masa Chips | Use code "REALALEXCLARK" for 20% OFF Wise Traditions | Use code “ALEX” for $25 OFF Nimi Skincare | Use code "ALEXCLARK" for 10% OFF YRefy | Call (888) 502-2612 Courtney Swan Instagram | @Realfoodology YouTube | @Realfoodology Website | www.realfoodology.com Realfoodology Podcast | @Realfoodology Alex Clark Instagram | @realalexclark Instagram | @poplitics Facebook | @realalexclark X (Twitter) | @yoalexrapz YouTube | @RealAlexClark Spotify | @Culture Apothecary Apple Podcasts | @Culture Apothecary 'Culture Apothecary' Merch OUT NOW! Glass tumblers, weekly wellness planners, hats, crewnecks and more. Use code "ALEXCLARK" for 10% OFF Join the Cuteservatives Facebook group to connect with likeminded friends who love America and all things health and wellness! Subscribe to ‘Culture Apothecary' on Apple Podcasts and Spotify. New episodes drop 6pm PST/ 9pm EST every Monday and Thursday. This show is made possible with generous donations from listeners who believe in our mission to heal a sick culture. You can support our show by leaving a tax deductible donation, or by subscribing to @realalexclark YouTube for FREE!

    The Underrated Bruno Leoni (with Michael Munger)

    Play Episode Listen Later Oct 13, 2024 77:48


    Econtalk Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgFriedrich Hayek credited Bruno Leoni with shaping his ideas on laws and legislation. James Buchanan said that Leoni identified problems that led to his own work on public choice. How is it possible, then, that so few of us know of the groundbreaking Italian political philosopher? Listen as Duke economist Michael Munger talks with EconTalk's Russ Roberts about Leoni's ideas and the gruesome murder that ended his life before its time.

    The Slave Trade

    Play Episode Listen Later Oct 6, 2024 63:31


    "History 102" with WhatifAltHist's Rudyard Lynch and Erik Torenberg Key Takeaways  Our society obsesses over African slavery; it has become a deep psychological neurosis that tears society apart Africa had three different slave trades from the Middle Ages to the 20th centuryThe internal African slave (the largest) The Muslim slave trade (selling slaves to the Muslim world; 2nd largest) The Western European slave trade (3rd largest)Throughout human history, Africa was the place that the most slaves were pulled out of – contrasted with other areas such as Europe and Asia, which had centralized governments that were able to protect their citizens Once Africa became a part of the global economy, it realized that it could offer slaves in exchange for goods and servicesThe vast majority of people involved in the African slave trade were black “I don't think any serious historian could ever support the 1619 Project who is not an ideologue. It's not even a historical argument; it's a political argument masquerading through history.” – Rudyard Lynch Because America was so wealthy, African-American slaves had a higher quality of living than the peasantries of Europe did; however, African-American slaves were disenfranchised from any sort of respect or social standards “I think the British ending slavery in the 1830s and 40s is one of the most admirable things a country has done.” – Rudyard Lynch The West practiced slavery, but it was also a society that ended it – which is historically rareAs religions developed and spread around the globe, they eventually abolished slavery among their people Read the full notes @ podcastnotes.orgIn this episode of History 102, WhatifAltHist creator Rudyard Lynch and Erik Torenberg discuss the history of the Muslim slave trade, a forgotten tragedy that predates and rivals the Atlantic slave trade in both scale and brutality. Dive into the complex dynamics and enduring impact of this dark chapter in African history, and explore the Muslim and internal slave trades while also challenging the 1619 Project's narrative. Learn about the broader context of global slavery, the complex origins of racial inequality, and the global network that fueled the transatlantic slave trade.

    Why Ultra-Processed Foods Are So Addictive

    Play Episode Listen Later Oct 4, 2024 59:14


    Doctor's Farmacy with Mark Hyman, MD Key Takeaways Everything sold at Whole Foods, Erewhon, or other specialty stores is not healthy; become a savvy shopper and don't fall into the trap Be wary of packaging: “If it has a health claim, it's not good for you.” – Mark HymanThe more ultra-processed foods make up your diet, the less nutritious your diet tends to be overall and the greater risk you are of developing chronic inflammatory diseases For every 10% of your diet that comes from ultra-processed foods, the risk of death increases by 14%The real risks of ultra-processed foods: Increase in cardiovascular death, increased risk of anxiety and depression, higher risk of type II diabetes, increased risk of Alzheimer's, increased risk of sleeping disorder, obesityHow did we get here? Simply put, there's a lot of money to be made by special industries and the governmentSolution: Ban pharmaceutical ads on TV and ads specifically targeting childrenRead the full notes @ podcastnotes.orgHave you ever wondered why it's so hard to put down that bag of chips? In this episode, my guests Dr. Shebani Sethi and Calley Means and I break down how ultra-processed foods are contributing to the obesity epidemic, diabetes, heart disease, and even mental health issues. From understanding the science of addiction to decoding food labels, we'll explore how big food companies are manipulating us—and what we can do to fight back. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman's Weekly Longevity Journal Full-length episodes of these interviews can be found here: Why the Last Thing that Should Ever Eat is Ultra Processed Foods: It Kills 11 Million People a Year How Does Ultra-Processed Food Affect Our Mental Health? Calley Means: The Obesity Crisis, Ozempic, ADHD and Food Industry Lies This episode is brought to you by Rupa Health, FOND, Ketone-IQ, and Happy Egg. Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com. Get 20% off one-time orders for both new and returning customers. Just visit FondBoneBroth.com and use code MARK20. Save 30% off your first subscription order & receive a free six-pack of Ketone-IQ with ketone.com/MARKHYMAN Shopping for better eggs shouldn't be confusing. Look for the yellow carton at your local grocery store or visit HappyEgg.com/Farmacy to find Happy Egg near you to get 50% off. Learn more about your ad choices. Visit megaphone.fm/adchoices

    Raw Milk: Everything You Need To Know | Dairy Farmer Rick Anglin

    Play Episode Listen Later Oct 4, 2024 57:04


    Culture Apothecary with Alex Clark Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgRaw milk farmer, Rick Anglin, used to be in the conventional dairy industry before switching to raw milk. His farm, Fond du Lac Farms, is the exclusive raw dairy provider to Sprouts grocery stores across the state of Arizona. Does hot coffee pasteurize raw milk? What is the listeria risk from consuming raw dairy? Should you only drink raw milk from grass-fed cows? Farmer Rick joins Alex to put raw milk conspiracies out to pasture. Thank You To Our Sponsors! Squeezed Juice | Use code “Alex” for 25% OFF at ⁠shop.squeezedjuice.com ⁠ Garnuu | Use code “Alex” for 15% OFF at ⁠garnuu.com⁠ Yrefy | Call (888) 502-2612 or visit ⁠yrefy.com Rick Anglin Instagram | @fonddulacfarms Facebook | @FondDuLacFarms X | @FondduLacFarms Website | fonddulacfarms.com Alex Clark Instagram | @realalexclark Instagram | @cultureapothecary Facebook | @realalexclark X | @yoalexrapz YouTube | @RealAlexClark Spotify | Culture Apothecary with Alex Clark Apple Podcasts | Culture Apothecary with Alex Clark New 'Culture Apothecary' Merch OUT NOW! Glass tumblers, weekly wellness planners, hats, crewnecks and more. Use code "Alex Clark" for 10% OFF at ⁠⁠⁠tpusamerch.com⁠ Got Raw Milk? Crop Top Join the Cuteservatives Facebook group to connect with likeminded friends who love America and all things health and wellness! ⁠⁠⁠⁠⁠Join the CUTEservative Facebook Group!⁠⁠⁠⁠ Subscribe to ‘Culture Apothecary' on ⁠Apple Podcasts⁠ and ⁠Spotify⁠. New episodes drop 6pm PST/ 9pm EST every Monday and Thursday. This show is made possible with generous donations from listeners who believe in our mission to heal a sick culture. You can support our show by leaving a tax deductible donation, or by subscribing to ⁠⁠@RealAlexClark⁠⁠ YouTube for FREE! ⁠⁠donate.tpusa.com⁠⁠ #cultureapothecary #alexclark #rawmilk #diet #food

    The Man Behind ChatGPT (Sam Altman Interview)

    Play Episode Listen Later Oct 1, 2024 48:38


    Write of Passage Podcast Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgYou know him as the CEO of OpenAI — but did you know that Sam Altman is an avid writer?  As one of today's most successful entrepreneurs, Sam champions the tremendous value of writing: how it clarifies your thinking, expands your ideas, and levels-up your life in every sense, both personally and professionally. Plus, he has a love for the creative. (Have you ever met someone who can recite Percy Bysshe Shelley poems from memory? Well, Sam can.)  In this episode, we discuss how Sam uses ChatGPT in his daily life; how LLMs are changing the future of writing; what it means to be a novelist in the age of technology; and Sam's best-learned writing lessons from Paul Graham. If you want to learn how the king of ChatGPT writes, this episode is for you.  SPEAKER LINKS:  Website: https://openai.com/ Blog: https://blog.samaltman.com/ Twitter: https://twitter.com/sama WRITE OF PASSAGE:  Want to learn more about the final class for Write of Passage? Click here: https://writeofpassage.com/ PODCAST LINKS:  Website: https://writeofpassage.school/how-i-write/ YouTube: https://www.youtube.com/@DavidPerellChannel/videos Apple: https://podcasts.apple.com/us/podcast/how-i-write/id1700171470 Spotify: https://open.spotify.com/show/2DjMSboniFAeGA8v9NpoPv Learn more about your ad choices. Visit megaphone.fm/adchoices

    Lulu Meservey - Transforming Company Narrative - [Invest Like the Best, EP.389]

    Play Episode Listen Later Sep 29, 2024 67:00


    Invest Like the Best Key Takeaways  “The founder has to be accountable for the story. The founder holds this secret knowledge and vision that other people do not.” – Lulu Meservey Go Direct: If the founder's secret has to go through seven layers of filtering before it is shared with the world, then it will become something that is already familiar to people and that already existsThe Core Ingredients of Founder Communications:1. Have a willingness and eagerness to take on the company's comms 2. Have a clear vision of the company's goals 3. Know your audience4. Reach people where they intellectually hang out“Communication is a vector, not a scalar. It only matters if there is a direction attached to it.” – Lulu Meservey Know your audience; if you are talking to the wrong people, then you would be better off talking to nobody because you may be making new enemies or unwanted friends Do not worry about converting your haters into believers; doing so successfully is so rare that it is probably not worth your scare timeKnow where your target audience intellectually hangs out so that your message can reach them in that medium Do not worry about converting your haters into believers; doing so successfully is so rare that it is probably not worth your scare time Craft your hook and know the erogenous zone of your target audience, then present them with a “gateway drug” that bridges them into the new world that you are creatingRead the full notes @ podcastnotes.orgMy guest today is Lulu Meservey. Lulu is the Founder and CEO of Rostra, a company that partners with founders to level up their communications around all strategic initiatives, from hiring to fundraising. She is also on the board at Shopify. I have been recently fascinated by the challenge of founders telling their story and Lulu is an expert in comms and a believer in creative problem-solving through effective communication and compelling storytelling. We discuss the evolution of media and its pitfalls, innovative methods for managing crises, and the power of going direct with your communication. Please enjoy my conversation with Lulu Meservey. I'm excited to announce that we are hiring an Editor in Chief at Colossus. This will be a critical and central role in our growing media platform and in our quest to find and showcase the best people, businesses, and ideas in the world. This person will work on existing shows like Invest Like the Best and Founders, our soon-to-be-announced print publication, and more. We aim to be the dominant media company exploring business and investing frontiers, so this person needs to be obsessed with these topics and bring serious operational chops. I firmly believe this role can help define someone's career. Go to joincolossus.com/eic to apply. Subscribe to Glue Guys! For the full show notes, transcript, and links to mentioned content, check out the episode page here. ----- This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform. — This episode is brought to you by Alphasense. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Imagine completing your research five to ten times faster with search that delivers the most relevant results, helping you make high-conviction decisions with confidence. AlphaSense provides access to over 300 million premium documents, including company filings, earnings reports, press releases, and more from public and private companies. Invest Like the Best listeners can get a free trial now at Alpha-Sense.com/Invest and experience firsthand how AlphaSense and Tegas help you make smarter decisions faster. ----- Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.  Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here. Follow us on Twitter: @patrick_oshag | @JoinColossus Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com). Show Notes: (00:00:00) Welcome to Invest Like the Best (00:06:48) The Evolution of Media and Communication (00:11:25) The Importance of Direct Communication for Founders (00:20:20) Choosing the Right Partners and Clients (00:25:20) The Art of Launching a Product (00:34:01) Fundraising Tips for Entrepreneurs and Investors (00:35:32) The Pitfalls of Inauthentic Fundraising (00:36:05) Crafting a Compelling Macro Narrative (00:37:54) Crisis Management Strategies for Founders (00:42:41) Lessons from Counterinsurgency (00:44:24) The Rugby Analogy for Founders (00:49:34) The Power of K-Pop Marketing (00:56:30) Vision and Future of Rostra (01:01:17) The Importance of Direct Communication (01:10:36) The Kindest Thing Anyone Has Done For Lulu

    #095 What Microplastics Are Doing to Your Brain, Body, and Reproductive Systems

    Play Episode Listen Later Sep 29, 2024 74:31


    Found My Fitness - Rhonda Patrick Key Takeaways Microplastics don't just vanish in our bodies, they accumulate; by understanding the sources, we can take preventive measures to avoid or minimize the use of harmful productsOnce microplastics enter our bodies, they can circulate in our bloodstream and deposit in various tissues and the bloodstream As our environmental plastic pollution increases, so does the accumulation in human tissueWhile the body does have mechanisms to clear toxins, we're in an almost constant cycle of consuming and clearing microplastics and associated chemicals (BPA, BPS, phthalates)Top sources of microplastic and chemical exposure: Water (both tap and bottled), air, synthetic clothing, food packaging, cookwareMicroplastics play an active role in damaging our organs, disrupting our hormones, impacting fertility, causing cancer, and possibly increasing the risk of neurodegenerative diseaseStrategies to reduce exposure to microplastics and associated chemicals: (1) Try to avoid packaged food, and especially heating food in plastic; (2) Consider setting up reverse osmosis filtration at home; (3) Reduce consumption of canned foods; (4) Use a mug or bring your own to a coffee shop; (5) Opt for cookware made of titanium, ceramic, cast iron; (6) Drink from glass bottles instead of plastic or cans; (7) Use a HEPA filter at home; (8) Try to wear clothing made of natural fibers like cotton, bamboo, linen, silkBe a savvy consumer: Many products labeled as BPA free still contain BPS (which is equally harmful) or phthalates (arguably more harmful)Read the full notes @ podcastnotes.org Sweating helps enhance microplastic-associated chemical excretion. Get my free sauna report when you sign up here for my newsletter. Discover my premium podcast, The Aliquot Every week, the average person ingests the equivalent weight of a credit card in plastic.* While certain preventive measures can significantly reduce your intake of these harmful substances, it's crucial to acknowledge a more daunting concern: the bioaccumulation of microplastics in the brain, potentially at ten times the rate of other organs. Microplastics and their associated chemicals are alarmingly ubiquitous — they permeate breast milk, sperm, the hippocampus, the prefrontal cortex, the air we breathe, medications, the water supply, and our bloodstream, accumulating in most major organ systems. During this episode, we'll explore the unsettling realities of microplastics and their associated chemicals, diving into how they infiltrate nearly every facet of our environment and body, and discuss actionable strategies to reduce exposure. Timestamps: (00:00) The extent of the problem (02:12) Top sources of exposure (04:00) Contamination of our water (05:04) BPA, phthalates, & PFAS (forever chemicals) (07:06) How heating plastic affects BPA exposure (09:21) Our unfortunate habit of eating credit cards (11:33) Microplastics in major organs (14:05) Crossing the blood-brain barrier (15:01) How microplastics affect a developing fetus (15:55) The bloodstream is a highway for microplastics (18:12) Endocrine and hormonal effects (23:09) Consequences in pregnant women (25:35) How phthalates affect reproductive health (26:36) BPA's involvement in autism spectrum disorder (29:58) Side effects of prenatal BPA exposure (32:18) The brain may be a super-accumulator of plastic (34:50) Human brain microplastic levels are rising (36:06) Lost fertility in women (38:07) Changes in sperm quality (39:23) Microplastics in sperm (40:59) Why the heart suffers (42:51) Microplastics in arterial plaque (43:56) How BPA affects blood pressure (45:58) Risk of cancer (50:31) Topo Chico sparkling water (53:02) Reverse osmosis filtration (54:56) Food-based strategies for limiting microplastics (56:32) The "myth" of BPA-free plastics (58:14) Is salt a source of microplastics? (59:18) HEPA filters (1:00:52) Choose your clothing wisely (1:01:47) How to prevent release of microplastics (from laundry) (1:02:32) Receipts and thermal paper (1:04:17) Microplastic excretion and breakdown (1:06:28) Sulforaphane for detoxifying (1:08:38) Can dietary fiber increase microplastic excretion? (1:10:15) Are plastic chemicals excreted through sweat? (1:11:21) Do excretion strategies work for "forever chemicals"? Show notes are available by clicking here Watch this episode on YouTube * Some sources suggesting this figure may need to be revised downward as a result of some disagreement on the math used. However, in spite of this lack of consensus, the human and animal intake of microplastics is substantial and pervasive.

    Managing nerves, anxiety, and burnout | Jonny Miller (Nervous System Mastery)

    Play Episode Listen Later Sep 29, 2024 74:15


    Lenny's Podcast: Product | Growth | Career ✓ Claim Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgJonny Miller is the founder of Nervous System Mastery, a course that has helped hundreds of founders and tech leaders cultivate calm, reduce nervousness, enhance resilience, and elevate their sense of aliveness. Having personally benefited from Jonny's teachings, I'm especially excited to have him on the show. In this episode, we discuss:• How shifting your focus from the mind to the body can help ease nervousness• The power of breath in changing states• The importance of “interoception”• Specific breathing exercises to both calm and excite your nervous system• The A.P.E. (awareness, posture, and emotion) framework for recognizing body signals• The “feather, brick, dump truck” phenomenon• The concept of emotional debt and how to release it• The competitive advantage of feeling emotions—Jonny's five-week boot camp, Nervous System Mastery, will equip you with evidence-backed protocols to cultivate greater calm and agency over your internal state. Learn to rewire maladaptive stress responses and improve your sleep (use code LENNY for $250 discount). Apply here.—Brought to you by:• Teal—Your personal career growth platform• Vanta—Automate compliance. Simplify security.• Miro—A collaborative visual platform where your best work comes to life—Find the full transcript at: https://www.lennysnewsletter.com/p/managing-nerves-anxiety-and-burnout—Where to find Jonny Miller:• X: https://twitter.com/jonnym1ller• LinkedIn: https://www.linkedin.com/in/jonnym1ller/• Website: https://www.jonnymiller.co/• Podcast: podcast.curioushumans.com • Email: jonny@curioushumans.com• Course: https://nsmastery.com/lenny—Where to find Lenny:• Newsletter: https://www.lennysnewsletter.com• X: https://twitter.com/lennysan• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/—In this episode, we cover:(00:00) Jonny's background(07:19) The bottom-up approach to nervousness and anxiety(09:42) The power of breath in changing states(11:47) The concept of state over story(13:56) Personal experiences with nervousness(15:01) Breathing exercises to calm you down(20:40) The “espresso” breath exercise to give you energy(25:44) Interoception and the A.P.E. framework(34:47) The “feather, brick, dump truck” phenomenon(37:40) Recognizing emotional debt and avoiding burnout(40:47) Using somatic-oriented therapy for healing(45:26) Telltale signs of emotional debt(48:13) The competitive advantage of “feeling the feels”(50:20) Advice for people overwhelmed by stimuli(52:36) The NSDR (non-sleep deep rest) practice for emotional release(55:38) Daily practices for emotional well-being(58:23) Thoughts on meditation(01:01:26) The Body Keeps the Score(01:01:58) Contrarian corner(01:04:43) Lightning round—Jonny's If [This] Then [Breathe] Recipes:• If [overwhelmed], then [hum]• If [anxious], then [breath of calm]• If [lethargic], then [espresso breath]—Referenced:• The Operating Manual for Your Nervous System: https://every.to/p/the-operating-manual-for-your-nervous-system• Afferent vs. Efferent Neurons: https://www.osmosis.org/answers/afferent-vs-efferent-neurons• Insular cortex: https://en.wikipedia.org/wiki/Insular_cortex• Jonny's TED Talk, “The gifts of grief”: https://www.ted.com/talks/jonny_miller_the_gifts_of_grief/details• Humming (Simple Bhramari Pranayama) as a Stress Buster: A Holter-Based Study to Analyze Heart Rate Variability (HRV) Parameters During Bhramari, Physical Activity, Emotional Stress, and Sleep: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182780/• 14-Minute Guided NSDR (non-sleep deep rest) practice: https://www.youtube.com/watch?v=vjXX2c72fYY• Breathing Techniques to Reduce Stress and Anxiety | Dr. Andrew Huberman on the Physiological Sigh: https://www.youtube.com/watch?v=kSZKIupBUuc• Interoception: the hidden sense that shapes well-being: https://www.theguardian.com/science/2021/aug/15/the-hidden-sense-shaping-your-wellbeing-interoception• Exteroception: https://dictionary.apa.org/exteroception• Interoceptive Awareness and ADHD: https://chadd.org/adhd-news/adhd-news-adults/interoceptive-awareness-and-adhd/• Childhood Trauma Affects Stress-Related Interoceptive Accuracy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813623/• The Hour Between Dog and Wolf: How Risk Taking Transforms Us, Body and Mind: https://www.amazon.com/Hour-Between-Dog-Wolf-Transforms/dp/0143123408• Somatic Experiencing: https://www.somaticexperiencing.com/• Hakomi Institute: https://hakomiinstitute.com/• Decisions and Desire (about Antonio Damasio's work): https://hbr.org/2006/01/decisions-and-desire• When enough is enough | Andy Johns (ex-FB, Twitter, Quora): https://www.lennyspodcast.com/when-enough-is-enough-andy-johns-ex-fb-twitter-quora/• What Is Yoga Nidra?: https://health.clevelandclinic.org/what-is-yoga-nidra• Becoming Fully Yourself, What AI Wants, Family Rituals & Rites of Passage, with Kevin Kelly: https://podcast.curioushumans.com/episodes/becoming-fully-yourself-what-ai-wants-rites-of-passage-with-kevin-kelly• Tim Ferriss: https://tim.blog/• The Power of Sensations: Intermediate's Vipassana Body Scan: https://insighttimer.com/carola.ananda/guided-meditations/the-power-of-sensations-intermediates-vipassana-body-scan-meditation• Vipassana Meditation: https://www.dhamma.org/en/index• The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma: https://www.amazon.com/Body-Keeps-Score-Healing-Trauma/dp/0670785938• Waking the Tiger: Healing Trauma: https://www.amazon.com/Waking-Tiger-Healing-Peter-Levine/dp/155643233X• Consolations: The Solace, Nourishment and Underlying Meaning of Everyday Words: https://www.themarginalian.org/2015/04/29/david-whyte-consolations-words/• The 15 Commitments of Conscious Leadership: A New Paradigm for Sustainable Success: https://www.amazon.com/15-Commitments-Conscious-Leadership-Sustainable/dp/0990976904/• The Conscious Leadership Group: https://conscious.is/• Recapture the Rapture: Rethinking God, Sex, and Death in a World That's Lost Its Mind: https://www.amazon.com/Recapture-Rapture-Rethinking-Death-World/dp/0062905465• Kubo and the Two Strings on Prime Video: https://www.amazon.com/Kubo-Two-Strings-Charlize-Theron/dp/B01K5BSWX0• Wolfwalkers on AppleTV+: https://tv.apple.com/us/movie/wolfwalkers/umc.cmc.amuoq00hqelfi98j0gvg641x• Scavengers Reign on Max: https://www.max.com/shows/scavengers-reign/50c8ce6d-088c-42d9-9147-d1b19b1289d4• Jerry Colonna on LinkedIn: https://www.linkedin.com/in/jerry-colonna-reboot/• Ra Optics “Sunset” blue-light blockers: https://raoptics.com/collections/night-lenses• Nurosym vagal stimulation device: https://my.nurosym.com/vns1564/• Pulsetto vagal stimulation device: https://pulsetto.tech/new-year/?gc_id=20124962116&h_ad_id=686249897188&gad_source=1• Apollo vagus nerve stimulator: https://apolloneuro.com/products/apollo-wearable—Additional research:• Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging: https://www.sciencedirect.com/science/article/pii/S0306453023003001• Somatic experiencing: using interoception and proprioception as core elements of trauma therapy: https://www.frontiersin.org/articles/10.3389/fpsyg.2015.00093/full• Relationship between interoception and emotion regulation: New evidence from mixed methods: https://www.sciencedirect.com/science/article/abs/pii/S0165032718323723• Out-of-the-blue panic attacks aren't without warning: body sends signals for hour before: https://pubmed.ncbi.nlm.nih.gov/21783179/—Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.—Lenny may be an investor in the companies discussed. Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe

    #132 Mike Benz - Inside the Censorship Industrial Complex

    Play Episode Listen Later Sep 26, 2024 165:32


    Shawn Ryan Show Key Takeaways  Populism in the new Communism; the same strategies that were used to fight and combat the spread of Communism during the Cold War are now used to fight populismGlobal censorship is not a “left vs right” issue; it is the Blob vs. populism The “Blob” as a term used to describe the entrenched foreign policy establishment in Washington, DCFollowing World War II, the Blob was created to influence events in foreign countries so that those events would suit the interests of the United StatesAfter 1948, the United States needed a new mechanism to maintain its empire – not by military means, but by political vassalage The US would intervene in countries that did not pose any national security threat but had resources or services that supported the interests of the US and its peopleStarting in 2016, the foreign-policy established institutions felt threatened that the entire rules-based international order might collapse due to nations pursuing their own nationalism; to combat this trend, the Blob created its online censorship apparatus around the year 2014 The Blob is used to prevent or handicap the rise of populist political candidates in a given region During the Cold War, the CIA and State Department viewed left-wing Communism as the ultimate threat; today, they view right-wing populism as the threat The US encourages nations to “strengthen its political process” by establishing robust counter-disinformation mechanisms so that it can be aligned with “democracy best practices” Government funding is being used to subsidize a censorship mercenary army; the complex would cease to exist if its funding was cut off “The American people are subsidizing their silence.” – Mike BenzIf the censorship-industrial complex reaches full maturity, then it will become as powerful as the military-industrial complex itself  Read the full notes @ podcastnotes.orgMike Benz is a former official with the U.S. Department of State, known for his work in international communications and digital freedom. He has played a significant role in advocating for internet freedom and the protection of online expression. Benz is the founder of the Foundation for Freedom Online, an organization dedicated to promoting free speech and digital rights around the world. His work focuses on countering authoritarian censorship and supporting the rights of individuals to access and share information freely. His background includes expertise in foreign affairs and digital policy, often emphasizing the importance of a free and open internet as a fundamental human right. Through his advocacy, Benz has sought to engage policymakers and the public on issues related to digital governance, censorship, and the implications of technology for democracy. Shawn Ryan Show Sponsors: https://preparewithshawn.com https://hillsdale.edu/srs https://www.fxnetworks.com/shows/the-old-man https://ShawnLikesGold.com | 855-936-GOLD #goldcopartner Mike Benz Links: FFO Foundation - https://foundationforfreedomonline.com X - https://x.com/mikebenzcyber IG - https://www.instagram.com/MikeBenzCyber Please leave us a review on Apple & Spotify Podcasts. Vigilance Elite/Shawn Ryan Links: Website | Patreon | TikTok | Instagram | Download Learn more about your ad choices. Visit podcastchoices.com/adchoices

    Daniel Yergin – Oil Explains the Entire 20th Century

    Play Episode Listen Later Sep 23, 2024 87:37


    The Lunar Society Daniel Yergin Books  “The Allies floated to victory on a sea of oil.” – Lord Curzon Access to oil resources was critical for the Allies' military operations, fueling their ships, planes, and machinery; this provided the Allies with a mobility advantage over the Germans Hydrocarbons have been the engine of economic development“World War II was not an oil war, but there was an oil war within World War II.” – Daniel Yergin When Hitler invaded Russia, he was not only going for Moscow but also for the oil fields in Baku Admiral Nimitz said if the Japanese had come back a third time and hit the oil tanks, then World War II in the Pacific would have taken another two years One reason why the Japanese Kamikaze flew into the aircraft carriers was to save fuel so that they did not have to fly backEnergy security as a national strategic imperative tends to fall out of focus until it hits you in the faceWarfare tends to be a beta-test environment for new technologies: World War I began with calvary and ended with tanks, airplanes, and motorcyclesAfter World War I, there were fears that the country would run out of oil; to mitigate this fear, the American government began to support American companies that wanted to expand into the Middle East Six out of every seven barrels of oil used by the Allies in WWII were produced by the United States  After World War II, all world leaders understood the significance of securing oil as a strategic resource Estimates suggest that by 2030, about 10% of electricity in the United States will go towards powering data centers; today, that figure is 4% Read the full notes @ podcastnotes.orgUnless you understand the history of oil, you cannot understand the rise of America, WW1, WW2, secular stagnation, the Middle East, Ukraine, how Xi and Putin think, and basically anything else that's happened since 1860.It was a great honor to interview Daniel Yergin, the Pulitzer Prize winning author of The Prize - the best history of oil ever written (which makes it the best history of the 20th century ever written).Watch on YouTube. Listen on Apple Podcasts, Spotify, or any other podcast platform. Read the full transcript here. Follow me on Twitter for updates on future episodes.Sponsors:This episode is brought to you by Stripe, financial infrastructure for the internet. Millions of companies from Anthropic to Amazon use Stripe to accept payments, automate financial processes and grow their revenue.This episode is brought to you by Suno, pioneers in AI-generated music. Suno's technology allows artists to experiment with melodic forms and structures in unprecedented ways. From chart-toppers to avant-garde compositions, Suno is redefining musical creativity. If you're an ML researcher passionate about shaping the future of music, email your resume to dwarkesh@suno.com.If you're interested in advertising on the podcast, check out this page.Timestamps(00:00:00) – Beginning of the oil industry(00:13:37) – World War I & II(00:25:06) – The Middle East(00:47:04) – Yergin's conversations with Putin & Modi(01:04:36) – Writing through stories(01:10:26) – The renewable energy transition Get full access to Dwarkesh Podcast at www.dwarkeshpatel.com/subscribe

    #443 – Gregory Aldrete: The Roman Empire – Rise and Fall of Ancient Rome

    Play Episode Listen Later Sep 22, 2024


    Artificial Intelligence Podcast Key Takeaways  The key to understanding Ancient Rome is to understand that it was obsessed with the pastThe Romans were hyper-competitive and cared deeply about their status amongst their peers; their public competitiveness drove themOne of the secrets to Rome's success was its ability to absorb and integrate non-Roman ideas “If we were to write a realistic textbook of the Roman Empire, nine out of ten chapters should be details of what it was like to be a small-time family farmer, because that's what 90% of the people in the ancient world did.” – Gregory AldreteRoman law is perhaps the most significant legacy the empire has left on the modern world; about 90% of the modern world uses some derivation of it The Great Contradiction: Rome's very success made almost every group within Roman society deeply unhappy and boiling with resentmentCaesar succeeded in taking over the state as one man, but he could not solve the problems of ruling Rome as one person and appearing to function as a king  Augustus is one of the most significant individuals in Roman history given he was the one who founded the Roman Empire; he led the transition from the republic to empirePublic speaking was an essential aspect of life in Rome; those who were great orators, such as Cicero, had a great advantage in seeking power and influence While Gladiators were considered low status – because they performed for others – many of them became wildly popular in Roman culture The Five Good Emperors period (96-180 CE) of Roman history is often seen as a high point in Roman history The five emperors were Nerva, Trajan, Hadrian, Antoninus Pius, and Marcus AureliusEventually, the Roman Empire became too large to effectively govern; a state of constant civil war ensured, which created a vicious downward cycle for the overall Roman economy that left it poorer and more vulnerable to fragmentationDifferent historians attribute the fall of the Roman Empire to different things, citing the barbarians, Christianity, climate, disease, and moral decline Read the full notes @ podcastnotes.orgGregory Aldrete is a historian specializing in ancient Rome and military history. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep443-sc See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: https://lexfridman.com/gregory-aldrete-transcript CONTACT LEX: Feedback - give feedback to Lex: https://lexfridman.com/survey AMA - submit questions, videos or call-in: https://lexfridman.com/ama Hiring - join our team: https://lexfridman.com/hiring Other - other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: Gregory's Website: https://gregorysaldrete.com/ Gregory's Books: https://amzn.to/3z6NiKC Gregory's Great Courses Plus: https://www.thegreatcoursesplus.com/gregory-s-aldrete Gregory's Audible: https://adbl.co/4e72oP0 SPONSORS: To support this podcast, check out our sponsors & get discounts: LMNT: Zero-sugar electrolyte drink mix. Go to https://drinkLMNT.com/lex Shopify: Sell stuff online. Go to https://shopify.com/lex AG1: All-in-one daily nutrition drinks. Go to https://drinkag1.com/lex BetterHelp: Online therapy and counseling. Go to https://betterhelp.com/lex ExpressVPN: Fast & secure VPN. Go to https://expressvpn.com/lexpod OUTLINE: (00:00) - Introduction (08:38) - Ancient world (22:34) - Three phases of Roman history (25:24) - Rome's expansion (37:04) - Punic wars (45:36) - Conquering Greece (47:14) - Scipio vs Hannibal (50:21) - Heavy infantry vs Cavalry (53:57) - Armor (1:06:48) - Alexander the Great (1:12:49) - Roman law (1:22:29) - Slavery (1:30:09) - Fall of the Roman Republic (1:33:54) - Julius Caesar (1:38:33) - Octavian's rise (1:48:25) - Cleopatra (1:56:47) - Augustus (2:24:57) - Religion in Rome (2:49:03) - Emperors (2:56:10) - Marcus Aurelius (3:02:21) - Taxes (3:05:29) - Fall of the Roman Empire (3:22:41) - Decisive battles (3:46:51) - Hope PODCAST LINKS: - Podcast Website: https://lexfridman.com/podcast - Apple Podcasts: https://apple.co/2lwqZIr - Spotify: https://spoti.fi/2nEwCF8 - RSS: https://lexfridman.com/feed/podcast/ - Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 - Clips Channel: https://www.youtube.com/lexclips

    The Greatest Coach of All Time: John Wooden

    Play Episode Listen Later Sep 21, 2024 70:09


    How to Take Over the World The story of how John Wooden won ten national championships on the way to becoming the greatest coach of all time. ----- Sponsors: Vesto Gains In Bulk - Use code Ben for $20 and a free shaker. How to Take Over the World Premium - For all endnotes, takeaways, and bonus episodes subscribe for only $7/month. ----- Writing, production, and sound editing by Ben Wilson with support from Michael Lackner. Learn more about your ad choices. Visit megaphone.fm/adchoices

    #317 ‒ Reforming medicine: uncovering blind spots, challenging the norm, and embracing innovation | Marty Makary, M.D., M.P.H.

    Play Episode Listen Later Sep 18, 2024 123:23


    Drive with Dr. Peter Attia Key Takeaways In medicine (and everywhere), there is a resistance to new ideas, tied to effort justification – the idea that you've spent so much time holding a certain belief, that the cost is too high to changeNothing in science is not 100% certain – there are no proofs; science is not a ‘thing' it's a process You shouldn't cling to hypotheses with absolute certainty and should be open to updating beliefs based on new information“Just having a crazy idea is not sufficient. You have to have a means of stating what a hypothesis is, determining how to test that hypothesis, and above all else – having the ability to update your hypothesis based on new, emerging information.” – Peter AttiaThe distrust in science and medicine is because there is no humility in walking back incorrect information; it's created two camps: (1) Blind faith in science and medicine; (2) Complete rejection of science and medicine “Women are confused because the same megaphone used to say estrogen causes breast cancer has not been used to correct course.” – Peter AttiaDon't throw out the baby with the bath water: “C-sections and antibiotics have saved more lives than anything that we're doing today. That has doubled the human lifespan.” – Peter AttiaThe vast majority of what we call ovarian cancer is a fallopian tube cancer We need to increase public awareness, we're targeting the wrong organAt Johns Hopkins, fallopian tubes are removed instead of tied to eliminate the 1 in 78 chance of getting ovarian cancerDifficulty in advancing knowledge: People are doing things in a blackhole with no scientific evidence – we need appropriate studies but the NIH controls $80 billion in research dollars The NIH doesn't fund big, new ideas – it funds small ideas that are a likely betWe don't have a vehicle to encourage big thinkersRead the full notes @ podcastnotes.org View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Marty Makary, a Johns Hopkins surgeon and New York Times bestselling author, returns to The Drive to discuss his latest book, Blind Spots: When Medicine Gets It Wrong, and What It Means for Our Health. In this episode, Marty explores how a new generation of doctors is challenging long-held medical practices by asking critical new questions. He discusses the major problems of groupthink and cognitive dissonance in the medical community and delves into several of the "blind spots" raised in the book, including treatments for appendicitis, the peanut allergy epidemic, misunderstandings about HRT and breast cancer, antibiotic use, and the evolution of childbirth. He explains the urgent need for reform in medical education and the major barriers standing in the way of innovative medical research. Throughout the conversation, Marty offers insightful reflections on where medicine has succeeded and where there's still room to challenge historic practices and embrace new approaches. We discuss: The issue of groupthink and cognitive dissonance in science and medicine [2:30]; How a non-operative treatment for appendicitis sheds light on cognitive dissonance [7:00]; How cognitive dissonance and effort justification shape beliefs and actions [13:15]; How misguided peanut allergy recommendations created an epidemic [17:45]; The enduring impact of misinformation and fear-based messaging around hormone replacement therapy allegedly causing breast cancer [25:15]; The dangers of extreme skepticism and blind faith in science, and the importance of understanding uncertainty and probability [28:00]; The overuse of antibiotics and the rise of antibiotic resistant infections and poor gut health [33:45]; The potential correlations between early antibiotic use and chronic diseases [40:45]; The historical and evolving trends in childbirth and C-section rates [50:15]; Rethinking ovarian cancer: recent data challenging decades of medical practice and leading to new preventive measures [1:05:30]; Navigating uncertainty as a physician [1:19:30]; The urgent need for reform in medical education [1:21:45]; The major barriers to innovative medical research [1:27:30]; The dogmatic culture of academic medicine: why humility and challenging established norms are key for progress [1:38:15]; The major successes and ongoing challenges of modern medicine [1:51:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

    10 Philosophy-Inspired Challenges for Becoming a Better and Happier Man

    Play Episode Listen Later Sep 13, 2024 49:43


    Art of Manliness Although they may call it different things and approach its attainment in different ways, many of the world's religions and philosophies have a similar goal: achieving a life of virtue, peace, and flourishing.In his new book, Seriously Happy, Ben Aldrige explains how anyone can use the wisdom of ancient traditions to improve themselves and live the Good life. Today on the show, Ben offers a thumbnail sketch of Buddhism, Cynicism, Taoism, Stoicism, Epicureanism, and Aristotelianism, along with practices and challenges inspired by these philosophies, including walking a banana, listening to a music performance without music, and taking a Wu Wei adventure, that you can use to put ancient wisdom into action and become a better and happier man.Resources Related to the PodcastBen's previous appearance on the AoM podcast: Episode #640 — Weird and Wonderful Ways to Get Comfortable Being UncomfortableAoM Podcast #148: Trying Not to TryWhy Buddhism is True: The Science and Philosophy of Meditation and Enlightenment by Robert WrightJohn Cage's 4'33”Albert Ellis' Rational Emotive Behavior TherapyConnect With Ben AldridgeBen's website

    Russell Brand on his Baptism, Big Pharma, Donald Trump, and the Globalists' Attempt to Become God

    Play Episode Listen Later Sep 8, 2024 101:26


    The Tucker Carlson Show Key Takeaways  The state of bewilderment that we are currently living through is beneficial to those in power because it grants them more control Those in power benefit from bewilderment, conflict, and chaos because it is easier to assert authority in these environments When a state of crisis benefits those in power, you can expect a perpetual state of crisis The state attempts to emulate the characteristics of God: omniscience, omnipresence, omnipotence, and glory  “Secularism is all well and good, as long as the state doesn't behave like a god.” – Russell Brand If you have a deep need for God, then be careful because the culture will try to fill that desire with false gods such as drugs, alcohol, money, and fameSee every person that you come across as a human being; be open to the idea that God is trying to speak to you through another personIf our communities are guided by God, then it is more likely that we will create communities, states, nations, and a planet of peace and prosperityfrom the bottom up, and not from the top down While technology has created the possibility of further decentralization of power, crises are being used to legitimize decentralization; those in power prefer the trajectory of totalitarianism and technological feudalism under the peculiar veil of kindness and protection Protection and control exist on a continuum; this dynamic is fine for a parent who is looking after her child, but not for a state and its people Read the full notes @ podcastnotes.orgTucker Carlson Live Tour in Phoenix, AZ. Russell Brand on his baptism and God's role in the battle against totalitarianism in the west. Paid partnerships with: ExpressVPN Get 3 months free at https://expressvpn.com/Tucker Eight Sleep Get $350 off the Pod 4 Ultra https://EightSleep.com/Tucker Learn more about your ad choices. Visit megaphone.fm/adchoices

    Matt Taibbi on the Global Censorship-Industrial Complex

    Play Episode Listen Later Sep 8, 2024 46:14


    Honestly with Bari Weiss ✓ Claim Key Takeaways  In the United States, free speech is not a right granted by the government but is considered an unalienable right of a human beingBut free speech is viewed differently in the European Union; for example, the French view free speech as needing to strike a balance between the individual and the community It was revealed during the “Twitter Files” controversy that American lobbyists wanted to push America more towards the European model of policing speech onlineThe state has figured out how to turn the Internet into an instrument of social control Counter-terrorism to Counter-populism: Many of the government agencies that once focused on stopping terrorist groups have shifted their focus inward domestically to monitor and censor American citizens The state uses “misinformation” as a pretext for guiding messagingThe gradual drift towards authoritarianism: People come to worship authority when the state “saves” them from every “emergency”Be wary of Language Inflation: A phenomenon in which extreme language is used to describe something that does not warrant the use of extreme language There is a natural political bias in government-sponsored censorship; the people who fill government censorship positions tend to come from left-leaning universities Read the full notes @ podcastnotes.orgIn the past few weeks, there's been an increasing number of threats to freedom of speech around the world. In France, authorities arrested Telegram CEO Pavel Durov for failing to adequately moderate content and prevent criminal activity on his platform.  In the UK, since the outbreak of anti-immigration riots, police have arrested individuals merely for posting comments online. The Labour-led government has suggested expanding measures to remove “legal but harmful” content.  In Brazil, President Lula's administration has proposed new regulations requiring social media companies to monitor and remove “harmful content,” and a Brazilian Supreme Court justice just banned X altogether in the country. The ruling came after the platform missed a deadline to name a new legal representative there. From Hungary to Pakistan, the right to speak your mind, particularly on the internet, is more precarious than ever.  Even in the United States, with our free speech rights enshrined in the Constitution, polls suggest an entire generation has grown up thinking it should be illegal to say something inaccurate or hateful. Democratic VP nominee Tim Walz said as much: “There's no guarantee to free speech on misinformation or hate speech, and especially around our democracy.” So how did we get here? And, where is this all going?  Today, Michael sits down with the intrepid journalist Matt Taibbi, who knows this issue inside out. When The Free Press launched, he reported the Twitter Files with Bari Weiss, and together they exposed how government agencies had pressured Twitter to censor undesirable information, including skepticism of Covid lockdowns and opposition to Covid-related public school closures.  In this conversation, Matt and Michael talk about what's happening in Europe, Brazil, and here in the U.S. They discuss the factors that precipitated the so-called “misinformation wars,” from 9/11 to Brexit and Trump's election, that convinced elites of the need to enforce restrictions on speech. And they talk about why these efforts are doomed to backfire.  If you liked what you heard from Honestly, the best way to support us is to go to thefp.com and become a Free Press subscriber today. Learn more about your ad choices. Visit megaphone.fm/adchoices

    #833 - Eric Weinstein - Are We On The Brink Of A Revolution?

    Play Episode Listen Later Sep 8, 2024 211:03


    Modern Wisdom Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.orgEric Weinstein is a mathematician, economist, former Managing Director of Thiel Capital and a podcaster. It feels like the world is reaching a fever-pitch. From deep fakes to cheap fakes, AI girlfriends to senile presidents, we've never had more access to information, and yet it's never been harder to work out what is true. So, what do we do? Expect to learn Eric's thoughts on the 2024 presidential election, whether we are being gaslit on a global scale by the media, the future of string theory and what's next for theoretical physics, why we have canned humour and what that means as a society, Eric's thoughts on Joe Rogan, what my biggest weaknesses as a human are and much more… Sponsors: See discounts for all the products I use and recommend: https://chriswillx.com/deals Get a Free Sample Pack of all LMNT Flavours with your first box at https://drinklmnt.com/modernwisdom (automatically applied at checkout) Get a 20% discount on Nomatic's amazing luggage at https://nomatic.com/modernwisdom (automatically applied at checkout) Get 5 Free Travel Packs, Free Liquid Vitamin D and more from AG1 at https://drinkag1.com/modernwisdom (automatically applied at checkout) Get $350 off the Pod 4 Ultra at https://eightsleep.com/modernwisdom (use code MODERNWISDOM) Extra Stuff: Get my free reading list of 100 books to read before you die: https://chriswillx.com/books Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom Episodes You Might Enjoy: #577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59 #712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf #700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp - Get In Touch: Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact - Learn more about your ad choices. Visit megaphone.fm/adchoices

    #094 Dr. Layne Norton on Building Muscle – Insights on Diet, Training, and Supplements

    Play Episode Listen Later Sep 4, 2024 214:35


    Found My Fitness - Rhonda Patrick Key Takeaways Tips for maintaining consistency: (1) What gets you excited to work out?; (2) What exercise do you enjoy and have low pain with?; (3) What will you execute consistently?Variables for building strength: (1) Mechanical tension; (2) Number of hard sets; (3) Training muscles at long lengths under tensionFactors that increase the risk of injury: (1) Increase in training load and/or volume when you aren't prepared; (2) Psychological stress – what happens in the mind affects the body (and what happens in the body affects the mind); (3) Sleep quality is a big lever for injury risk and pain management Form doesn't move the needle on injury risk – tissue adaptation matters more“The best time to start lifting weights is right now.” – Layne NortonHave joint pain or never exercised? Start with lighter weights and movements that either don't cause pain or induce less painIt almost doesn't matter what you start with – do whatever keeps you consistentMost practical tip for protein intake: Shoot for about 1g/lb bodyweight – or more depending on goals, but consume as much as you want balancing other macros to be properly fueled for exercise and recoverySeed oils are contributing to the health crisis – but probably not because they're inherently bad Seed oils are not innocuous but energy toxicity is a big chunk of what's happening, we're eating too much and moving too littleSeed oils are also more representative of consuming more processed foodsBottom line: There is no strong evidence to avoid seed oils, as long as you're still controlling for overall diet quality and calories – focus on diet quality and the bigger picture“Have guidelines, not rules.” – Layne NortonMost people believe what they want to believe regardless of the evidenceSticking to water is good, but if you switch to no- or low-calorie drink from full calories, it will save a ton of caloriesKeeping your body fat down is the best way to protect your health; how you get there is less important than getting there – the most important thing is consistencySupplements won't do the work for you but they might help you recover fasterRead the full notes @ podcastnotes.orgGet my exact protocols for boosting levels of brain-derived neurotrophic factor (BDNF) and enhancing cognition Discover my premium podcast, The Aliquot Dr. Layne Norton is a Ph.D. in Nutritional Sciences, a professional bodybuilder, and a champion powerlifter. We discuss why most people aren't training too hard, when to go to failure, whether seed oils are “the” central cause of chronic disease, why having a slow metabolism isn't a credible reason for being overweight (for most), and the sustaining power of good habits. We also get into controversies around the carnivore diet, diet sodas, artificial sweeteners, intermittent fasting, and much more. Timestamps: (00:00) Introduction (04:48) Layne's coaching philosophy (14:39) Why to start tracking calories (for at least 3 days) (17:41) Why people lie to themselves about food intake (23:06) The profound benefits of small exercise doses (26:53) Why you should treat exercise like brushing your teeth (30:11) Benefits of resistance training for older individuals (33:51) Should you train to failure? (47:07) Why hard training & consistency trump exercise selection (56:46) Is lifting heavy necessary for building muscle? (57:54) Barbell vs. hack squats for preventing falls (1:00:10) Can lifting weights decrease low-back pain? (1:01:43) Injury prevention when resistance training (1:11:16) How exposure therapy can help you with injuries (1:15:04) Why pain doesn't always indicate tissue injury (1:18:17) Should you resistance train after a poor night of sleep? (1:21:57) Why menopause can cause weight gain (1:29:36) Why it's never too late to start lifting weights (1:32:05) Resistance training tips for older individuals with joint pain (1:36:18) Why total protein intake matters more than distribution (1:44:19) Layne's daily protein distribution (1:46:44) The shortcomings of nutrition studies (1:54:06) Is consuming more than 1.6 g/kg of protein beneficial? (1:55:33) Should you eat more protein in a calorie deficit? (1:56:43) Protein intake for endurance athletes (1:58:07) How much protein does Layne eat? (1:59:11) Are seed oils a predominant cause of chronic disease? (2:08:45) Does the carnivore diet increase heart disease risk? (2:14:16) Are heated seed oils more inflammatory? (2:20:33) Is there a "big food" industry conspiracy? (2:26:17) Are sugar-sweetened beverages uniquely deleterious? (2:30:17) Can diet soda help you lose weight? (2:34:20) Microbiome & cancer risks of diet soda (2:42:02) Is drinking 1 Diet Coke per day unhealthy? (2:44:24) Why Layne rarely takes a strong position on early science (2:49:04) Carnivore diet (3:01:52) Time-restricted eating (3:12:38) Layne's daily routine (3:16:55) Layne's diet and supplements (3:19:49) Creatine and hair loss (3:22:49) Rhodiola rosea & ashwagandha (3:25:54) Layne's tier 2 supplements Show notes are available by clicking here Watch this episode on YouTube  

    Gurwinder Bhogal's Guide to Modern Survival (EP.231)

    Play Episode Listen Later Sep 1, 2024 100:13


    Infinite Loops Key Takeaways Check out the episode pageRead the full notes @ podcastnotes.org“We have created for ourselves a world that we didn't evolve for.” Gurwinder Bhogal is, for my money, one of the most independent, original and insightful thinkers you'll find in our corner of the internet. He returns to discuss how willpower and good old-fashioned human agency can help us reclaim our mental sovereignty and escape the “constant avalanche of concerns that are being vomited over us through our laptop screens, our phones, our TV screens, and in conversations.” For the full transcript, episode takeaways, and bucketloads of other stuff designed to make you go, “Hmm, that's interesting!” check out our Substack. Important Links: Gurwinder's Substack  Gurwinder's Twitter Gurwinder's previous Infinite Loops appearance Show Notes: “We have created for ourselves a world we didn't evolve for” The dogged persistence of our stubborn beliefs Gamification; generational differences in agency The societal impact of the education system's changing priorities How to zombify a population Skin in the game: Gurwinder's guide to reclaiming agency LLMs, bullshit, and the atomization of culture How to play better games Willpower is the bottleneck Gurwinder as emperor of the world MORE! Books Mentioned: Why Everything is Becoming a Game; by Gurwinder Bhogal Think Again: The Power of Knowing What You Don't Know; by Adam Grant The Status Game: On Human Life and How to Play It; by Will Storr The True Believer: T