POEM of the Week Podcast

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Each week, Dr. Mark Ebell, POEMs Editor, joins Dr. Michael Wilkes, NPR correspondent and Vice-Dean of the UC-Davis Medical School, for a five minute discussion about an important recent medical study reviewed by the POEMs editors. POEMs provide synopsised reviews of studies that could affect a clini…

Mark Ebell and Michael Wilkes


    • Mar 20, 2023 LATEST EPISODE
    • infrequent NEW EPISODES
    • 6m AVG DURATION
    • 167 EPISODES

    4.7 from 91 ratings Listeners of POEM of the Week Podcast that love the show mention: ebm, review, thank, great.



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    Latest episodes from POEM of the Week Podcast

    Episode 657: Early invasive strategy does not reduce mortality for moderate to severe ischemic heart disease after 5.8 years (ISCHEMIA-EXTEND)

    Play Episode Listen Later Mar 20, 2023 6:41


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Early invasive strategy does not reduce mortality for moderate to severe ischemic heart disease after 5.8 years (ISCHEMIA-EXTEND) '

    Episode 656: Among antidepressants, only serotonin-norepinephrine reuptake inhibitors are effective for pain

    Play Episode Listen Later Mar 13, 2023 4:59


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Among antidepressants, only serotonin-norepinephrine reuptake inhibitors are effective for pain '

    Episode 655: Low FODMAPS diet is better than an oral spasmolytic for irritable bowel syndrome (NNT = 7 – 9)

    Play Episode Listen Later Mar 6, 2023 6:33


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Low FODMAPS diet is better than an oral spasmolytic for irritable bowel syndrome (NNT = 7 – 9) '

    Episode 654: Letrozole more efficacious than clomiphene for infertility treatment among individuals with polycystic ovarian syndrome

    Play Episode Listen Later Feb 27, 2023 4:31


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Letrozole more efficacious than clomiphene for infertility treatment among individuals with polycystic ovarian syndrome '

    Episode 653: Brief behavioral therapy diminishes insomnia in the elderly

    Play Episode Listen Later Feb 20, 2023 5:54


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Brief behavioral therapy diminishes insomnia in the elderly '

    Episode 652: Mindfulness-based stress reduction is noninferior to escitalopram for adults with anxiety disorder

    Play Episode Listen Later Feb 13, 2023 7:16


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Mindfulness-based stress reduction is noninferior to escitalopram for adults with anxiety disorder '

    Episode 651: No benefit with torsemide over furosemide for posthospitalization treatment of heart failure (TRANSFORM-HF)

    Play Episode Listen Later Feb 6, 2023 5:27


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' No benefit with torsemide over furosemide for posthospitalization treatment of heart failure (TRANSFORM-HF) '

    Episode 650: Lecanemab does not significantly improve cognition in early Alzheimer's disease, is expensive, and causes brain edema and hemorrhage in some patients

    Play Episode Listen Later Jan 30, 2023 8:38


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Lecanemab does not significantly improve cognition in early Alzheimer's disease, is expensive, and causes brain edema and hemorrhage in some patients '

    Episode 649: Chlorthalidone no better than hydrochlorothiazide for hypertension

    Play Episode Listen Later Jan 23, 2023 6:26


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Chlorthalidone no better than hydrochlorothiazide for hypertension '

    Episode 648: Twice-daily low-dose aspirin is similar to enoxaparin for thromboprophylaxis after inpatient treatment for fracture (PREVENT CLOT)

    Play Episode Listen Later Jan 16, 2023 6:34


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Twice-daily low-dose aspirin is similar to enoxaparin for thromboprophylaxis after inpatient treatment for fracture (PREVENT CLOT) '

    Episode 647: Tell patients their new knee won't wear out sooner with hard use

    Play Episode Listen Later Jan 9, 2023 7:33


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Tell patients their new knee won't wear out sooner with hard use '

    Episode 646: Majority of CIN2 regress in women aged 25 to 30 years

    Play Episode Listen Later Jan 2, 2023 6:08


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Majority of CIN2 regress in women aged 25 to 30 years '

    Episode 645: Morning and bedtime dosing of antihypertensives have similar rates of major cardiovascular events (TIME)

    Play Episode Listen Later Dec 26, 2022 5:00


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Morning and bedtime dosing of antihypertensives have similar rates of major cardiovascular events (TIME) '

    Episode 644: Use of ACEIs and ARBs in advanced chronic kidney disease does not worsen, and may improve, renal outcomes

    Play Episode Listen Later Dec 19, 2022 7:08


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Use of ACEIs and ARBs in advanced chronic kidney disease does not worsen, and may improve, renal outcomes '

    Episode 643: Invitation to a single colonoscopy has only modest impact on colorectal cancer incidence (NordICC)

    Play Episode Listen Later Dec 12, 2022 7:17


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Invitation to a single colonoscopy has only modest impact on colorectal cancer incidence (NordICC) '

    Episode 642: Tocilizumab beneficial for adults with persistent polymyalgia rheumatica symptoms who receive steroid therapy

    Play Episode Listen Later Dec 5, 2022 5:20


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Tocilizumab beneficial for adults with persistent polymyalgia rheumatica symptoms who receive steroid therapy '

    Episode 641: Improved decongestion with the addition of acetazolamide to intravenous loop diuretics for acute heart failure

    Play Episode Listen Later Nov 28, 2022 5:04


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Improved decongestion with the addition of acetazolamide to intravenous loop diuretics for acute heart failure '

    Episode 640: Rebound symptoms common with COVID-19 even after placebo treatment

    Play Episode Listen Later Nov 21, 2022 5:42


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Rebound symptoms common with COVID-19 even after placebo treatment '

    Episode 639: Limited evidence for meds, music, and massage to treat anxiety in residents of long-term care facilities

    Play Episode Listen Later Nov 14, 2022 6:23


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Limited evidence for meds, music, and massage to treat anxiety in residents of long-term care facilities '

    Episode 638: Percutaneous coronary intervention does not improve outcomes for patients with ischemic heart disease and LVEF of less than 35%

    Play Episode Listen Later Nov 7, 2022 5:59


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Percutaneous coronary intervention does not improve outcomes for patients with ischemic heart disease and LVEF of less than 35% '

    Episode 637: Nonpharmacologic approaches can improve fibromyalgia symptoms

    Play Episode Listen Later Oct 31, 2022 4:44


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Nonpharmacologic approaches can improve fibromyalgia symptoms '

    Episode 636: Amitriptyline, duloxetine, and pregabalin each effective in decreasing pain from diabetic peripheral neuropathy; combinations even better

    Play Episode Listen Later Oct 24, 2022 5:35


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Amitriptyline, duloxetine, and pregabalin each effective in decreasing pain from diabetic peripheral neuropathy; combinations even better '

    Episode 635: Liraglutide probably the best second drug to prevent cardiovascular events in patients with T2DM who take metformin

    Play Episode Listen Later Oct 17, 2022 7:08


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Liraglutide probably the best second drug to prevent cardiovascular events in patients with T2DM who take metformin '

    Episode 634: Polypill better for secondary cardiovascular prevention than physician-directed care

    Play Episode Listen Later Oct 10, 2022 7:39


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Polypill better for secondary cardiovascular prevention than physician-directed care '

    Episode 633: Nirmatrelvir/ritonavir (Paxlovid) reduces hospitalization, mortality in patients 65+ with COVID-19; effect on younger patients unclear

    Play Episode Listen Later Oct 3, 2022 6:10


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Nirmatrelvir/ritonavir (Paxlovid) reduces hospitalization, mortality in patients 65+ with COVID-19; effect on younger patients unclear '

    Episode 632: Likelihood of long COVID varies by variant, sex, and vaccination status

    Play Episode Listen Later Sep 26, 2022 5:58


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Likelihood of long COVID varies by variant, sex, and vaccination status '

    Episode 631: Pharmacogenomic testing for selection of antidepressant provides minimal, if any, benefit (PRIME)

    Play Episode Listen Later Sep 19, 2022 5:44


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Overuse alert: Pharmacogenomic testing for selection of antidepressant provides minimal, if any, benefit (PRIME) '

    Episode 630: Greater social determinants of health burden associated with an increased risk of hospitalization

    Play Episode Listen Later Sep 12, 2022 6:50


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Greater social determinants of health burden associated with an increased risk of hospitalization '

    Episode 629: Tirzepatide helps obese adults without diabetes lose 15% to 21% of their body weight over 72 weeks

    Play Episode Listen Later Sep 5, 2022 7:26


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Tirzepatide helps obese adults without diabetes lose 15% to 21% of their body weight over 72 weeks '

    Episode 628: Supplemental vitamin D does not reduce the risk of fracture in older adults (VITAL)

    Play Episode Listen Later Aug 29, 2022 8:12


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Supplemental vitamin D does not reduce the risk of fracture in older adults (VITAL) '

    Episode 627: Screening for atrial fibrillation in primary care is not effective (VITAL-AF)

    Play Episode Listen Later Aug 22, 2022 6:51


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Screening for atrial fibrillation in primary care is not effective (VITAL-AF) '

    Episode 626: Fewer than 4% of children with newly diagnosed hypertension in primary care or school settings have secondary causes

    Play Episode Listen Later Aug 15, 2022 5:00


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Fewer than 4% of children with newly diagnosed hypertension in primary care or school settings have secondary causes '

    Episode 625: Minimal difference, if any, in the efficacy of intramuscular vs intra-articular steroid injection for knee osteoarthritis

    Play Episode Listen Later Aug 8, 2022 6:42


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Minimal difference, if any, in the efficacy of intramuscular vs intra-articular steroid injection for knee osteoarthritis '

    Episode 624: Long-term risks are similar for CT and invasive coronary angiography as initial diagnostic strategy for stable chest pain

    Play Episode Listen Later Aug 1, 2022 6:50


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Long-term risks are similar for CT and invasive coronary angiography as initial diagnostic strategy for stable chest pain '

    Episode 623: Medication abortion for pregnancy of unknown location a reasonable option

    Play Episode Listen Later Jul 25, 2022 7:32


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Medication abortion for pregnancy of unknown location a reasonable option '

    Episode 622: USPSTF 2022 recommends against initiating aspirin for primary prevention of cardiovascular disease in adults 60+ years (D recommendation)

    Play Episode Listen Later Jul 18, 2022 7:00


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' USPSTF 2022 recommends against initiating aspirin for primary prevention of cardiovascular disease in adults 60+ years (D recommendation) '

    Episode 621: Aducanumab is not effective for mild cognitive impairment or mild Alzheimer's dementia and has major safety issues

    Play Episode Listen Later Jul 11, 2022 8:27


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Aducanumab is not effective for mild cognitive impairment or mild Alzheimer's dementia and has major safety issues '

    Episode 620: Surgery is no better than nonoperative treatment for Achilles tendon rupture in adults

    Play Episode Listen Later Jul 4, 2022 5:35


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Surgery is no better than nonoperative treatment for Achilles tendon rupture in adults '

    Episode 619: Ketamine reduces suicidal ideation quickly, but may not reduce the short-term likelihood of suicide attempts

    Play Episode Listen Later Jun 27, 2022 5:53


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Ketamine reduces suicidal ideation quickly, but may not reduce the short-term likelihood of suicide attempts '

    Episode 618: Combination antidepressant therapy is more effective than monotherapy for acute severe depression and nonresponding depression

    Play Episode Listen Later Jun 20, 2022 5:55


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Combination antidepressant therapy is more effective than monotherapy for acute severe depression and nonresponding depression '

    Episode 617: Closed-loop system improves glycemic control but not hypoglycemia for young children with type 1 diabetes mellitus

    Play Episode Listen Later Jun 13, 2022 5:38


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Closed-loop system improves glycemic control but not hypoglycemia for young children with type 1 diabetes mellitus '

    Episode 616: Selective serotonin reuptake inhibitors are probably the best first option for patients with panic disorder

    Play Episode Listen Later Jun 6, 2022 6:14


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Selective serotonin reuptake inhibitors are probably the best first option for patients with panic disorder '

    Episode 615: All-cause mortality is comparable in patients with left main coronary artery disease treated with PCI or CABG

    Play Episode Listen Later May 30, 2022 5:00


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' All-cause mortality is comparable in patients with left main coronary artery disease treated with PCI or CABG '

    Episode 614: MA: Several drugs are effective for weight loss in obese or overweight adults; it's unclear whether they improve health outcomes

    Play Episode Listen Later May 23, 2022 7:01


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' MA: Several drugs are effective for weight loss in obese or overweight adults; it's unclear whether they improve health outcomes '

    Episode 613: Large increases in the risk of cardiovascular events following COVID-19 infection that required hospitalization

    Play Episode Listen Later May 16, 2022 7:19


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Large increases in the risk of cardiovascular events following COVID-19 infection that required hospitalization '

    Episode 612: Thromboprophylaxis after discharge improves clinical outcomes for certain high-risk patients hospitalized with COVID-19 (MICHELLE)

    Play Episode Listen Later May 9, 2022 6:11


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Thromboprophylaxis after discharge improves clinical outcomes for certain high-risk patients hospitalized with COVID-19 (MICHELLE) '

    Episode 611: Ibuprofen, ketorolac, and diclofenac are equivalent for the treatment of acute nonradicular low back pain

    Play Episode Listen Later May 2, 2022 5:23


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Ibuprofen, ketorolac, and diclofenac are equivalent for the treatment of acute nonradicular low back pain '

    Episode 610: Proton pump inhibitor use associated with an increased risk of gastric cancer

    Play Episode Listen Later Apr 25, 2022 7:00


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Proton pump inhibitor use associated with an increased risk of gastric cancer '

    Episode 609: British Society of Gastroenterology guidelines for the management of irritable bowel syndrome

    Play Episode Listen Later Apr 18, 2022 6:39


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' British Society of Gastroenterology guidelines for the management of irritable bowel syndrome '

    Episode 608: Nirmatrelvir/ritonavir (Paxlovid) reduces risk of hospitalization in at-risk outpatients (EPIC-HR)

    Play Episode Listen Later Apr 11, 2022 6:50


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' Nirmatrelvir/ritonavir (Paxlovid) reduces risk of hospitalization in at-risk outpatients (EPIC-HR) '

    Episode 607: No improved patient-oriented outcomes with sacubitril/valsartan in adults with heart failure and preserved EF (PARALLAX)

    Play Episode Listen Later Apr 4, 2022 6:40


    Dr. Ebell and Dr. Wilkes discuss the POEM titled ' No improved patient-oriented outcomes with sacubitril/valsartan in adults with heart failure and preserved EF (PARALLAX) '

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