Podcast appearances and mentions of Vinay Prasad

TWiV reviews fradulent science becoming an industry, FDA may not authorize Pfizer COVID vaccine for young kids, Kennedy won't push strict pesticide regulations conserved betacoronavirus sequences recognized by human T cells, and Bispecific antibodies protect against herpes recurrent disease. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Frontiers in Comparative Systems Virology Fradulent science becomes an industry (Science) FDA may not authorize Pfizer COVID vaccine for young kids (CIDRAP) Kennedy Won't Push Strict Pesticide Regulations (NY Times) Conserved betacoronavirus sequences recognized by human T cells (Cell) Bispecific antibodies protect against herpes recurrent disease (Cell Rep) Letters read on TWiV 1245 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – New Study Suggests Using AI Made Doctors Less Skilled at Spotting Cancer Alan – Save the Microbes effort gets off the ground Vincent – Dr. Vinay Prasad's Catch-22: The Only Way He Can Truly Succeed at His Job is to Get Fired Again Listener Picks Chaim – “Virus Hunters” by Greer Williams Bridget – Wave Life Sciences and their potential treatment for Alpha-1 antitrypsin deficiency Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Abdul and Katelyn condemn the violence at the CDC headquarters last week, and the startlingly weak response from lawmakers. Then they unpack Trump's newest executive order, which seeks to give his own appointees the power to approve federal grants. They also discuss the future of the FDA as Vinay Prasad makes his return, following his resignation last month. Then Abdul talks to Sherrell Byrd, founder of SOWEGA Rising, which has organized in rural Georgia to bring fresh produce to rural communities that lack grocery stores. They discuss the health implications of food deserts, and how food justice can change lives. Check out our shop at store.americadissected.com for our new America Dissected merch – including logo shirts, hoodies and mugs. And don't miss our “Vaccines Work. Science Matters.” t-shirts! This show would not be possible without the generous support of our sponsors. America Dissected invites you to check them out. This episode was brought to you by: Quince: Go to Quince.com/AD for free shipping on your order and 365-day returns.

Phase III data from Lilly's orforglipron in obesity fell short of investor expectations, but they appear to be enough to obtain approval and wide use. On the latest BioCentury This Week podcast, BioCentury's analysts discuss why the first-in-class oral small molecule GLP-1R agonist's clean safety profile and clear manufacturing advantage over oral peptides give the product a leg-up in the market.They then discuss Vinay Prasad's return to FDA after a brief hiatus, the revamped strategy of 32-year-old San Diego biotech Acadia Pharmaceuticals, and an attempt in the Senate to revive the Biosecure Act targeting China biotechs.Finally, the analysts preview this year's Back to School package, which reimagines FDA. At a time of unprecedented change in government agencies, BioCentury's 33rd Back to School asks what FDA could look like if it were reorganized from the ground up to create the regulator patients deserve and industry needs. View full story: https://www.biocentury.com/article/656727#orforglipron #CBER #VinayPrasad #AcadiaPharmaceuticals00:00 - Introduction00:49 - Prasad07:09 - Back to School12:29 - Lilly Obesity21:58 - Acadia's Comeback28:50 - Biosecure ActTo submit a question to BioCentury's editors, email the BioCentury This Week team at podcasts@biocentury.com.Reach us by sending a text

0:00 FOX's Greg Gutfeld appearance w Jimmy Fallon makes liberal media furious! Robby Soave | RISING 9:29 Trump eyes deploying National Guard in DC, vows to evict homeless | RISING 18:43 Trump orders Pentagon to use military force against foreign drug cartels: NYT | RISING 23:12 Poll: 60% blame Trump for high costs amid expensive AF1, ballroom projects! Lindsey Granger | RISING 32:00 Mamdani called out for rent-stabilized apartment, Cuomo: 'move out' | RISING 41:26 ' AI chatbots deluding users with made-up answers: NYT | RISING 46:58 Vinay Prasad reinstated as FDA's top vaccine regulator after being pressured into resigning | RISING 55:44 Jimmy Kimmel, Sarah Silverman defend Joe Rogan, skewer overly-critical liberals | RISING Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode of GEN's Touching Base spotlights the unexpected relationship between breathing low oxygen and restoration of neuron function in a mouse model of Parkinson's disease. In addition, a single gene therapy injected at birth now offers lasting protection from HIV in infant rhesus macaques. Rounding out our episode, we discuss key factors shaping this year's A-List of Top 10 U.S. Biopharma Clusters and recap the regulatory conflict surrounding Sarepta Therapeutics' Duchenne muscular dystrophy (DMD) gene therapy, Elevidys®—including the departure of Vinay Prasad, MD, the FDA official behind the agency's brief get-tough approach.Join GEN editors Corinna Singleman, PhD, Alex Philippidis, Fay Lin, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base:GLP-1 Drug Semaglutide Linked to Reduced Muscle Strength in MiceGEN, August 6, 2025Out of Thin Air: Hypoxia Reverses Parkinson's Symptoms in MiceBy Fay Lin, PhD GEN, August 6, 2025Early Gene Therapy Provides Lasting HIV Protection in Newborn PrimatesGEN, July 30, 2025StockWatch: As Prasad Exits FDA, Analysts See Benefit for Sarepta, CGT StocksBy Alex Philippidis, GEN Edge, August 3, 2025Sarepta to Resume Shipping DMD Gene Therapy to Ambulant PatientsBy Alex Philippidis, GEN Edge, July 28, 2025Sarepta Under Scrutiny, AstraZeneca's Big Bet, and AI vs. IDRsBy Alex Philippidis, Uduak Thomas, Fay Lin, PhD, Corinna Singleman, PhD, GEN, July 25, 2025About Face: Sarepta to Pause Elevidys Shipments TemporarilyBy Alex Philippidis, GEN Edge, July 21, 2025Touching Base PodcastHosted by Corinna Singleman, PhDBehind the BreakthroughsHosted by Jonathan D. Grinstein, PhDThe State of Biotech Summit Registration Hosted on Acast. See acast.com/privacy for more information.

Abdul unpacks the week in public health, which includes: Vinay Prasad's exit from FDA Susan Monarez's confirmation to lead CDC New childhood vaccination data The EPA's move to rollback the endangerment finding Why more experts have been ousted from ACIP Then Abdul interviews professor Dr. Brian Willoughby about his research on porn use among young people, and what parents should know about modern porn content. Note: We recorded this episode before RFK Jr announced the cancellation of $500 million in funding for mRNA vaccine development. However, Abdul and Katelyn discussed the threat of mRNA research cuts in our May 7 and June 3 episodes. (their May convo begins at 00:11:00 / their June convo begins at 00:16:00) Check out our shop at store.americadissected.com for our new America Dissected merch – including logo shirts, hoodies and mugs. And don't miss our “Vaccines Work. Science Matters.” t-shirts! 

With Susan Monarez in at CDC and Vinay Prasad out at FDA, change is underway at HHS. Meanwhile, Secretary Robert F. Kennedy Jr. is calling out the Vaccine Injury Compensation Program as “a morass of inefficiency, favoritism, and outright corruption,” where injured families are stonewalled instead of supported. Del breaks down how victims face a court with no judge, no jury, and no real science. Could this be the administration that finally fixes it?Become a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

We drown in waves of ideological fluidity as the gurusphere continues to crash all around us.Supplementary Material 3400:00 Introduction01:26 Irish Stew and Dog Exercise Report03:45 A new 276 IQ Genius11:47 Fresh and Fit Antisemitism16:51 Are things getting dumber?21:22 Asmongold on the Epstein Files24:53 Epstein Conspiratorial Discourse helps Ghislaine Maxwell29:00 Vinay Prasad resigns from his MAGA position31:17 Eric Weinstein is the Architect of the Great Reset!32:37 Google Eyed Loons vs. Willing Apparatchik36:40 The Young Turks are joined by... Scott Adams38:51 Ana Kasparian sits down with Tucker Carlson44:46 Jimmy the Giant enters the arena46:11 Jimmy the Giant meets Konstantin Kisin57:12 Debating the Middle Class YouTube Grifters01:06:15 The Gurusphere Grift01:08:16 Jimmy the Giant reflects on his performance01:11:16 Discourse standards for Research01:15:05 Jimmy defends his criticisms01:22:27 Jimmy the Giant deletes his videos and apologises to Konstantin01:28:04 The Call to Action to support the Grand Mission01:32:32 Separating Issues from Support of Influencers01:37:13 Jimmy the Giant explains how the Elites created Wokeness01:47:16 Woke Wars and Psyops01:49:33 The Right Wing Media Outrage Ecosystem01:55:26 False Consciousness and the Billionaires02:02:47 AI limitations and Hallucinations02:07:08 Post Hoc-Reasoning in AI and People02:14:22 OutroThe full episode is available for Patreon subscribers (2hrs 16 mins).Join us at: https://www.patreon.com/DecodingTheGurusSourcesYounghoon Kim: World's Highest IQ Score (276) Scientifically Documented in New Academic PreprintFresh and Fit idiots being giggly anti-semitic and praising HitlerJoanne Freeman: The Field of Blood: Violence in Congress and the Road to Civil WarGhislaine Maxwell moved to Federal prison camp in TexasComment on the move from Prison ConsultantPoor Vinay Prasad – The Disgraceful Campaign Against a Top FDA OfficialEric responds to accusations that he is the mastermind behind the Great ReplacementTYT's The Conversation: Scott Adams Reflects on Life after his Terminal Cancer DiagnosisAna Kasparian on the Tucker Carlson showClips from now deleted Triggernometry video: He Called me a Grifter… it didn't go so well

Center for Drug Evaluation and Research Head George Tidmarsh will oversee the Center for Biologics Evaluation and Research on an acting basis after Vinay Prasad's abrupt departure hours after the recording of last week's episode of The Weekly. While the situation is being billed as temporary, rumors are swirling that structural changes may be afoot at the FDA with Commissioner Marty Makary looking for better drug, biologic alignment.Meanwhile, the agency has come under criticism for another recent decision—one apparently driven by CDER's Oncology Center of Excellence director Richard Pazdur: the rejection of Replimmune's advanced melanoma drug, RP1. According to reporting by multiple outlets, Pazdur opposed the consensus opinion of CBER staff to approve the drug. The research team behind Replimmune's Phase III study penned an open letter to the FDA on Friday responding to the issues outlined in the agency's complete response letter. Meanwhile, the FDA's Sarepta saga continues, highlighting “unprecedented” FDA leaks and a veritable communications disaster.On the business side of biopharma, Q2 earnings continue to unfurl, with Pfizer, Vertex, BioNTech, Merck and Moderna all reporting this past week. Merck's $3 billion savings push has claimed 6,000 jobs, contributing to a brutal July that saw the entire biopharma industry axe 7,900 employees, a 487% year-over-year increase, based on BioSpace tallies. Meanwhile, Pfizer CEO Albert Bourla confirmed he has been in direct contact with President Donald Trump to negotiate a path forward on Most Favored Nation drug pricing after the president sent letters to 17 Big Pharma companies—and posted on his Truth Social platform—asking them to comply with the policy within 60 days or face potential unspecified consequences.In other policy news, the Centers for Medicare and Medicaid Services is reportedly considering coverage of GLP-1 drugs for weight management and obesity—reviving a Biden era proposal the Trump admin scrapped earlier this year.Finally, in BioPharm Executive this week, we have a special report on the situation in China as international drugmakers swoop into the region to find new drug candidates, while other companies build their therapeutic farm systems from incubators and venture arms. And check out BioSpace's brand new Manufacturing Brief, where we bring you the latest news and analysis in the area of biopharma manufacturing, starting with a feature on how to make cell and gene therapies commercially viable.

The ouster of Vinay Prasad after three months running FDA's Center for Biologics Evaluation and Research could signal a reset is ahead for CBER. On the latest BioCentury This Week podcast, BioCentury's analysts discuss what the latest shakeup at the regulatory agency says about what's next for FDA.The analysts also assess two leading European pharmas: obesity and diabetes company Novo Nordisk, which named a new CEO last week while cutting its 2025 forecast, and Bayer, which is gearing up for launches and is revamping its pipeline to restart growth. Finally, they discuss the promising clinical data that's reviving interest in masking technologies that conditionally activate biologics.View full story: https://www.biocentury.com/article/656649#FDA #CBER #NovoNordisk #ObesityDrugs #Bayer01:05 - Prasad's Ouster14:59 - Novo's New CEO21:14 - Bayer's Growth Strategy26:05 - Masked BiologicsTo submit a question to BioCentury's editors, email the BioCentury This Week team at podcasts@biocentury.com.Reach us by sending a text

In this episode, we break down the high-profile firing of Dr. Vinay Prasad from his FDA leadership post. Once hailed as a contrarian voice in medicine, Prasad quickly became a polarizing figure both inside and outside the agency. We explore the tangled web of political infighting, pressure from Big Pharma, the biotech industry, and conspiracy theorists like Laura Loomer—and why this decision may have less to do with science and more with chaos at the top. Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.  

The new U.S.–EU trade deal negotiated between Donald Trump and the EU's Ursula von der Leyen is surprisingly one-sided in favor of the United States. In the end Europe made major concessions, including accepting a 15% tariff on goods and agreeing to purchase $750 billion worth of U.S. energy, while the U.S. gave up virtually nothing in return. Although European leaders were unhappy with the deal, they accepted it to avoid a full-blown trade war, with critics like former Belgian Prime Minister Guy Verhofstadt calling it disastrous and poorly negotiated.  Jimmy argues that Europe weakened its own position by severing energy ties with Russia and becoming dependent on U.S. energy and defense, effectively allowing Trump to dictate the terms. He and Americans' Comedian Kurt Metzger conclude that European leaders have sold out their own nations' interests to serve U.S. and transnational elite agendas, leaving their populations economically disadvantaged and politically powerless. Plus segments with Children's Health Defense CEO Mary Holland on the newly confirmed CDC head and the surprise departure of Dr. Vinay Prasad from the FDA, and a closing segment on rocker Dave Matthews' recent statement of support for Palestine. Also featuring Stef Zamorano!

Der populäre Hämato-Onkologe Vinay Prasad ist von seinem Amt bei der US-Arzneibehörde FDA zurückgetreten.

President Trump announced a major trade deal with South Korea, securing $350 billion in U.S.-directed investments, $100 billion in energy purchases, and a 15% tariff on Korean goods, while U.S. exports face zero tariffs. U.S. GDP grew 3% in Q2 2025, surpassing expectations, with inflation dropping to 2.1%, prompting optimism from the White House despite the Federal Reserve holding interest rates steady. Nancy Pelosi endorsed a congressional insider trading ban after Trump accused her of profiting from insider knowledge, while a new Stanford study revised COVID vaccine lives saved to 2.5 million globally, far below WHO's 14.4 million estimate. U.S. fertility rates hit a record low of 1.6 children per woman, with a Georgian church-led initiative cited as a model for reversing declines, and Senator Josh Hawley's $600 tariff rebate proposal sparked debate as a morally questionable gimmick.   Trump South Korea trade deal, U.S. GDP growth, inflation rate, Josh Hawley, tariff rebates, Nancy Pelosi, insider trading, COVID vaccine study, U.S. fertility rate, Georgian Orthodox Church, Cincinnati violence, Vinay Prasad, FDA

Howie and Harlan discuss Dr. Vinay Prasad's departure from the FDA after a backlash against his decisions on Sarepta's Duchenne muscular dystrophy gene therapy. Also examined: AI in clinical settings, changes in NIH grantmaking, and the 60th anniversary of Medicare and Medicaid. Links: Sarepta and the FDA “STAT breaks down the confusing, heartbreaking Sarepta saga” “Sarepta Therapeutics' Duchenne therapy faces ‘arduous' path back to market, senior FDA official says” “For many Duchenne families, halt to gene therapy is heartbreak upon heartbreak” “FDA launches probe into new Elevidys death as Sarepta, Roche stress gene therapy not at fault” “FDA Recommends Removal of Voluntary Hold for Elevidys for Ambulatory Patients” “FDA takes U-turn on Sarepta's Elevidys, backing Duchenne gene therapy again in ambulatory patients” “Controversial FDA official Dr. Vinay Prasad departs agency” “Top F.D.A. Vaccine Official Resigns, Citing Kennedy's ‘Misinformation and Lies'” “Vinay Prasad Is a Bernie Sanders Acolyte in MAHA Drag” “Timeline: The Rise and Fall of Vioxx” “What have we learnt from Vioxx?” THC in pizza dough “C.D.C. Ties 85 Cases of THC-Related Symptoms to Wisconsin Restaurant” “Tetrahydrocannabinol Intoxication from Food at a Restaurant — Wisconsin, October 2024” NIH funding “NIH is shrinking the number of research projects it funds due to a new Trump policy” NIH: Supporting Fairness and Originality in NIH Research Applications “Fearful of AI-generated grant proposals, NIH limits scientists to six applications per year” “Trump budget draft proposes NIH consolidation and 40% spending cut” Raw milk “Outbreak of Salmonella Typhimurium Infections Linked to Commercially Distributed Raw Milk — California and Four Other States, September 2023–March 2024” “The Dangers of Raw Milk: Unpasteurized Milk Can Pose a Serious Health Risk” AI in healthcare update “Ambience Healthcare Announces $243 Million Series C to Scale its AI Platform for Health Systems” “As ambient scribes face off, Doximity lures doctors with a free option” Aidoc: “AI Empowering Radiologists” “Clinical Implementation of a Combined Artificial Intelligence and Natural Language Processing Quality Assurance Program for Pulmonary Nodule Detection in the Emergency Department Setting” “Large Language Models as an Inexpensive and Effective Extra Set of Eyes in Radiology Reporting” “Current Trends in Remote and Flexible Work Options in Radiology and Perception of Impact on Radiologist Well-being” Medicare and Medicaid 60th anniversary CMS' program history “Medicare and Medicaid turn 60 – and face historic cuts decades in the making” UnitedHealth and Medicare Advantage “UnitedHealth says 2025 earnings will be worse than expected as high medical costs dog insurers” “UnitedHealthcare to exit certain Medicare Advantage markets as costs balloon, impacting 600K enrollees” “Novo Nordisk slides further on US competition, new CEO concerns” “Dems Must Really Fix Medicaid, Not Just Undo Trump's Damage to It”   Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world.Vinay Prasad's departure from CBER has analysts anticipating a more traditional successor, while GSK streamlines its pipeline and pledges billions in US investments. Susan Monarez is now the confirmed CDC director, and the top biopharma venture capital raises of H1 2025 are summarized. Despite challenges like layoffs and market fluctuations, GSK remains committed to investing in the US despite tariffs. Other headlines include Madrigal's potential $2 billion investment, Biogen and Eisai's Alzheimer's drug update, and Novo Nordisk's new leadership. Trilink Biotechnologies is offering self-amplifying RNA constructs for potential therapeutic advancements.AI biotech companies have secured substantial funding in the first half of 2025, with continued investment pouring into startups within the industry. The top five biopharma venture capital raises of this period are highlighted. There is confusion surrounding Ira's definition of 'drug,' potentially hindering companies from pursuing approval for new formulations and indications. Vinay Prasad's departure from the FDA's Center for Biologics Evaluation and Research, following controversies related to Sarepta, has raised concerns among developers. Despite challenges, four biotech companies are successfully launching their products independently.Over 260 million people are impacted by rare diseases, emphasizing the need for faster evidence generation through global real-world data. GSK's commitment to investing in the US, Merck's cost-cutting measures to support its launch schedule, and Novo Nordisk's new leadership are also highlighted. The FDA has updated regulations regarding Sarepta's DMD gene therapy, making it available for ambulatory patients. Adaptimmune anticipates significant staff reductions following a cell therapy asset sale. Stay tuned for more updates on the latest developments in the biopharma industry.

Howie and Harlan discuss Dr. Vinay Prasad's departure from the FDA after a backlash against his decisions on Sarepta's Duchenne muscular dystrophy gene therapy. Also examined: AI in clinical settings, changes in NIH grantmaking, and the 60th anniversary of Medicare and Medicaid. Links: Sarepta and the FDA “STAT breaks down the confusing, heartbreaking Sarepta saga” “Sarepta Therapeutics' Duchenne therapy faces ‘arduous' path back to market, senior FDA official says” “For many Duchenne families, halt to gene therapy is heartbreak upon heartbreak” “FDA launches probe into new Elevidys death as Sarepta, Roche stress gene therapy not at fault” “FDA Recommends Removal of Voluntary Hold for Elevidys for Ambulatory Patients” “FDA takes U-turn on Sarepta's Elevidys, backing Duchenne gene therapy again in ambulatory patients” “Controversial FDA official Dr. Vinay Prasad departs agency” “Top F.D.A. Vaccine Official Resigns, Citing Kennedy's ‘Misinformation and Lies'” “Vinay Prasad Is a Bernie Sanders Acolyte in MAHA Drag” “Timeline: The Rise and Fall of Vioxx” “What have we learnt from Vioxx?” THC in pizza dough “C.D.C. Ties 85 Cases of THC-Related Symptoms to Wisconsin Restaurant” “Tetrahydrocannabinol Intoxication from Food at a Restaurant — Wisconsin, October 2024” NIH funding “NIH is shrinking the number of research projects it funds due to a new Trump policy” NIH: Supporting Fairness and Originality in NIH Research Applications “Fearful of AI-generated grant proposals, NIH limits scientists to six applications per year” “Trump budget draft proposes NIH consolidation and 40% spending cut” Raw milk “Outbreak of Salmonella Typhimurium Infections Linked to Commercially Distributed Raw Milk — California and Four Other States, September 2023–March 2024” “The Dangers of Raw Milk: Unpasteurized Milk Can Pose a Serious Health Risk” AI in healthcare update “Ambience Healthcare Announces $243 Million Series C to Scale its AI Platform for Health Systems” “As ambient scribes face off, Doximity lures doctors with a free option” Aidoc: “AI Empowering Radiologists” “Clinical Implementation of a Combined Artificial Intelligence and Natural Language Processing Quality Assurance Program for Pulmonary Nodule Detection in the Emergency Department Setting” “Large Language Models as an Inexpensive and Effective Extra Set of Eyes in Radiology Reporting” “Current Trends in Remote and Flexible Work Options in Radiology and Perception of Impact on Radiologist Well-being” Medicare and Medicaid 60th anniversary CMS' program history “Medicare and Medicaid turn 60 – and face historic cuts decades in the making” UnitedHealth and Medicare Advantage “UnitedHealth says 2025 earnings will be worse than expected as high medical costs dog insurers” “UnitedHealthcare to exit certain Medicare Advantage markets as costs balloon, impacting 600K enrollees” “Novo Nordisk slides further on US competition, new CEO concerns” “Dems Must Really Fix Medicaid, Not Just Undo Trump's Damage to It”   Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

A top official at the Food and Drug Administration steps down after the agency changes course on a treatment for Duchenne muscular dystrophy. What does this episode say about the Trump Administration's approach toward drug development and innovation? Plus, Robert F. Kennedy Jr. says he plans to overhaul the National Vaccine Injury Compensation Program. Learn more about your ad choices. Visit megaphone.fm/adchoices

A massive 8.8-magnitude earthquake off Russia's Kamchatka Peninsula triggers tsunami warnings for Hawaii, Alaska, and the U.S. West Coast, with Japan's Pacific coast expecting waves up to 3 yards. The quake, the largest since 2011, causes minor damage in Russia. The Senate confirms Trump's DOJ nominee Emil Bove as a federal judge in a 50-49 vote. Dr. Vinay Prasad resigns from the FDA after facing Big Pharma backlash. Trump reflects on sparing Hillary Clinton from prosecution, contrasting it with the Russiagate hoax. Ron DeSantis criticizes H-1B visa abuse, and ICE arrests a Jamaican overstaying his visa, hired as a Maine police officer. Senator Josh Hawley proposes $600 tariff rebates for Americans. Job vacancies drop to 7.4 million.   Tsunami warning, Kamchatka earthquake, Shane Tamura, Manhattan shooting, emil Bove, Vinay Prasad, Trump administration, Ron DeSantis, H-1B visas, Josh Hawley, tariff rebates, economy

The morning after the FDA's vaccine regulator Dr. Vinay Prasad announced his resignation, FDA Commissioner Dr. Marty Makary shares the agency's position on the measles vaccine, Sarepta's Duchenne therapy, and the addictive kratom-derived compound OH-7. Booking Holdings CEO Glenn Fogel discusses the impact of geopolitics on travel to the U.S. While Canadians and Europeans are still traveling, the operator of Agoda, Priceline, and Kayak says they're going to Mexico and Asia, instead of the U.S. Plus, Wall Street remembers the lives lost in Monday's shooting, the first tsunami waves from Russia's 8.8 earthquake have hit Hawaii's shores, and CNBC's Eamon Javers reports on his conversation with Treasury Secretary Scott Bessent about trade talks with China. Eamon Javers - 07:24Dr. Marty Makary - 18:51Glenn Fogel - 36:48 In this episode:Eamon Javers, @EamonJaversJoe Kernen, @JoeSquawk Becky Quick, @BeckyQuickAndrew Ross Sorkin, @andrewrsorkinKatie Kramer, @Kramer_Katie

What happens when the loudest anti-vaccine voices stop podcasting and start running the FDA? In this explosive episode, Jonathan Howard and Wendy unpack how Drs. Marty Makary and Vinay Prasad — once champions of vaccine skepticism — are now in charge of public health policy… and finding themselves at war with the very conspiracy movement they courted. From quoting dubious anecdotes as “data” to downplaying real virus-related deaths while obsessing over vaccine side effects, their hypocrisy is staggering. Even MAGA influencers and anti-vax leaders are turning on them for not going far enough. The leopards are eating their faces — and we're here to document the carnage. Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.  

Just a few weeks ago, it seemed like Sarepta had weathered a spate of bad news, after two patients died from liver injuries from its Duchenne muscular dystrophy gene therapy Elevidys. Then came news of a third patient death. Last Wednesday, the company announced a major restructuring and 500-person layoff.  Then, in just a few days time, Sarepta Therapeutics went from enjoying a notable stock bump in response to that corporate update to its lowest price in nearly 10 years as it halts shipments of Elevidys. In addition to requesting the shipment hold, the FDA revoked the company's technology platform designation and paused all clinical trials for Sarepta's limb-girdle muscular dystrophy (LGMD) gene therapy. The turmoil was set in motion by media reports that a patient who received the LGMD treatment had died—a fact the company chose not to disclose during an investor call. In other news, the FDA's Center for Drug Evaluation and Research gets a new director in biotech veteran George Tidmarsh, also an adjunct professor of pediatrics and neonatology at Stanford University's School of Medicine. Tidmarsh enters the agency at a time of mass layoffs as well as voluntary departures. Meanwhile, Replimmune and Roche suffer FDA rejections as therapies from Otsuka/Lundbeck and GSK fail to earn adcomm support, as the bar for acceptable controls and demonstrations of efficacy continue to change under FDA commissioner Marty Makary and CBER director Vinay Prasad.  Finally, Big Pharmas continue to pump billions into U.S. manufacturing, with Biogen and AstraZeneca joining the list of companies to have made such pledges, pledging $2 billion and $50 billion, respectively. These latest announcements come as President Donald Trump reiterates that pharma-specific tariffs of up to 200% could come as soon as Aug. 1. 

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world.George Tidmarsh, a biopharma veteran and adjunct professor at Stanford's medical school, has been appointed as the new head of the FDA's Center for Drug Evaluation and Research (CDER). His extensive industry experience will be valuable in his new government position. Data secrecy among cell and gene therapy developers is hindering progress in the field, causing fragmentation, stalling innovation, and delaying access to treatments. Meanwhile, Sarepta is facing challenges with its elevidys shipments and has lost platform designation for its technology. At the same time, Roche's phase III trial in COPD has failed, impacting the market path for astegolimab. Layoffs are happening at companies like GSK, Sail, and BioNTech. Experts are exploring new ways to overcome barriers in cell therapy production.Data secrecy among cell and gene therapy developers continues to hinder progress and access to treatments. Acadia has introduced a new team and pipeline with ambitious goals. Patients are fighting for access to Brainstorm's ALS drug after promising real-world data. Moderna's withdrawal of its flu vaccine has left combination flu/COVID-19 vaccines in limbo. In other news, Sarepta is facing challenges with its DMD gene therapy, Ultragenyx's gene therapy for Sanfilippo syndrome is rejected by the FDA, GSK's Blenrep loses an adcomm vote, and BMS' anemia drug Reblozyl fails a Phase III trial. The FDA is experiencing layoffs and employee turnover amid an overhaul. Vinay Prasad overruled reviewers on Moderna's COVID-19 shot for kids. Upcoming events include a webinar on AI for real-world research and job opportunities in the biopharma industry. Readers are encouraged to provide feedback and suggest topics for future coverage.

Dr. Jonathan Howard and Wendy Orent unpack the ongoing collapse of trust in America's public health institutions, focusing on how FDA leaders Marty McCarey and Vinay Prasad weaponized vaccine myocarditis to undermine COVID vaccination efforts. With pediatric illnesses rising and the agency under fire from both scientists and extremists, this episode reveals how selective concern and ideological doublespeak are fueling a dangerous breakdown in science-based policy. It's a sobering look at the cost of playing politics with public health.   Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.

The FDA is unraveling. Scientists are being fired, vaccine access is shrinking, and top researchers are fleeing the country. And at the center of the storm? RFK Jr.'s appointees—Marty Makary and Vinay Prasad—men who once sat behind keyboards criticizing pandemic policy, now wield real power with devastating results. In this week's episode, Jonathan and Wendy walk us through the chaos: from dismissals without explanation to fabricated claims about who's being laid off, to the surreal moment when the very people who told us COVID was like the flu are now deciding who gets vaccinated. They call out journalist John Tierney for whitewashing pandemic history and expose the hypocrisy of pundits who cheered on herd immunity while vilifying actual public health officials. This isn't just a takedown—it's a warning. When contrarians become the establishment, science doesn't just get silenced. It gets rewritten. The FDA is unraveling. Scientists are being fired, vaccine access is shrinking, and top researchers are fleeing the country. And at the center of the storm? RFK Jr.'s appointees—Marty Makary and Vinay Prasad—men who once sat behind keyboards criticizing pandemic policy, now wield real power with devastating results. In this week's episode, Jonathan and Wendy walk us through the chaos: from dismissals without explanation to fabricated claims about who's being laid off, to the surreal moment when the very people who told us COVID was like the flu are now deciding who gets vaccinated. They call out journalist John Tierney for whitewashing pandemic history and expose the hypocrisy of pundits who cheered on herd immunity while vilifying actual public health officials. This isn't just a takedown—it's a warning. When contrarians become the establishment, science doesn't just get silenced. It gets rewritten.   Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.  

DITCH YOUR DOCTOR! https://www.livelongerformula.com/wam Get a natural health practitioner and work with Christian Yordanov! Mention WAM and get a FREE masterclass! You will ALSO get a FREE metabolic function assessment! GET YOUR APRICOT SEEDS at the life-saving Richardson Nutritional Center HERE: https://rncstore.com/r?id=bg8qc1 Use code JOSH to save money! HELP SUPPORT US AS WE DOCUMENT HISTORY HERE: https://gogetfunding.com/help-keep-wam-alive/# GET NON-MRNA FREEZE DRIED MEAT HERE: https://wambeef.com/ Use code WAMBEEF to save 20%! GET HEIRLOOM SEEDS & NON GMO SURVIVAL FOOD HERE: https://heavensharvest.com/ USE Code WAM to save 5% plus free shipping! Josh Sigurdson reports on the news of the FDA approving Moderna's Covid-19 "vaccine" for children ages 6 months to 11 years old in the latest attempt to poison and kill children. The so-called "vaccine" called Spikevax is being pushed by the FDA's top vaccine official Dr. Vinay Prasad. Simultaneously, the CDC's insane incoming head Susan Monarez continues to claim the covid shots are "safe and effective" and promotes giving it to your child. The CDC is expanding access to RSV vaccines and RFK Jr. has endorsed the Meningococcal vaccine as a "safe option." Vaccine lobbyists are even endorsing RFK Jr. and so-called MAHA. RFK Jr. who people must remember was confirmed by a pharma funded house also promoted the MMR Measles vaccine recently as well as wearable traceable devices being attached to all people in the United States in the next 4 years. Why would anyone be surprised? All the while, the Netherlands court case against Bill Gates which represents 7 vaccine injury claimants is heating up as one of the two lawyers, Arno van Kessel is imprisoned by the government in a high security prison. Hollywood actress Michelle Pfeiffer has launched attacks on Bill Gates, claiming that Gates is poisoning America's food supply which there is no doubt about at this point. And finally among many other stories, fear mongering is heating up regarding a new drug resistant bat-human hybrid flu. Likely an illegitimate attempt to force people under new mandates once again. Stay tuned for more from WAM! Get local, healthy, pasture raised meat delivered to your door here: https://wildpastures.com/promos/save-20-for-life/bonus15?oid=6&affid=321 USE THE LINK & get 20% off for life and $15 off your first box! SIGN UP FOR HOMESTEADING COURSES NOW: https://freedomfarmers.com/link/17150/ Get Prepared & Start The Move Towards Real Independence With Curtis Stone's Courses! GET YOUR WAV WATCH HERE: https://buy.wavwatch.com/WAM Use Code WAM to save $100 and purchase amazing healing frequency technology! GET ORGANIC CHAGA MUSHROOMS HERE: https://alaskachaga.com/wam Use code WAM to save money! See shop for a wide range of products! GET AMAZING MEAT STICKS HERE: https://4db671-1e.myshopify.com/discount/WAM?rfsn=8425577.918561&utm_source=refersion&utm_medium=affiliate&utm_campaign=8425577.918561 USE CODE WAM TO SAVE MONEY! GET YOUR FREEDOM KELLY KETTLE KIT HERE: https://patriotprepared.com/shop/freedom-kettle/ Use Code WAM and enjoy many solutions for the outdoors in the face of the impending reset! BUY GOLD HERE: https://firstnationalbullion.com/schedule-consult/ PayPal: ancientwonderstelevision@gmail.com FIND OUR CoinTree page here: https://cointr.ee/joshsigurdson PURCHASE MERECHANDISE HERE: https://world-alternative-media.creator-spring.com/ JOIN US on SubscribeStar here: https://www.subscribestar.com/world-alternative-media For subscriber only content! Pledge here! Just a dollar a month can help us alive! https://www.patreon.com/user?u=2652072&ty=h&u=2652072 BITCOIN ADDRESS: 18d1WEnYYhBRgZVbeyLr6UfiJhrQygcgNU World Alternative Media 2025

On this explosive Independence Day episode of We Want Them Infected, hosts Dr. Jonathan Howard and Wendy Orent unravel a sobering transformation in U.S. public health. With agencies like the ACIP and NIH now steered by politically motivated leaders like RFK Jr., Vinay Prasad, and Jay Bhattacharya, science is taking a backseat to ideology. They dive deep into the disastrous ACIP meeting stacked with anti-vaccine appointees, the chilling disinformation from NIH and FDA leadership, and the real-world impact—from cancer patients being denied life-saving clinical trials to families unable to access COVID vaccines. This episode is a powerful wake-up call for anyone concerned about science, truth, and the future of medicine. Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.  

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are shocked at how vaccine safety is undercut by misrepresenting thimerosal safety, its removal from vaccines, and how CBER director Vinay Prasad overruled his advisors for the administration of COVID vaccines to pregnant people knowingly compromising their health, before Dr. Griffin reviews recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center's long COVID treatment center, where to go for answers to your long COVID questions, association of long COVID and cognitive changes as well as the development of type I diabetes and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Thimerosal and Vaccines (FDA) Thimerosal-containing vaccines and neurodevelopmental outcomes (CDC) Thimerosal and Vaccines (CDC: Vaccine safety) WHO says ‘no evidence of harm' from thimerosal (Reuters) RFK Jr.'s Vaccine Panel Has a New Approach: Question Everything (Wall Street Journal) COVID-19 infection poses higher risk for myocarditis than vaccines (American Heart Association) Top F.D.A. Official Overrode Scientists on Covid Shots (NY Times) Who Sets the Immunization Schedule? (CDC: Vaccines for your children) Recommended Child and Adolescent Immunization Schedule for ages 18 years or younger (CDC) H5 bird flu: current situation (CDC: Avian Influenza) Assessing the transmissibility and outbreak risk of measles in the United States, 2024 – 2030 (JID) Proof of a measles vaccine for travelers coming from various countries, including the United States (US Embassy in Honduras) More measles outbreaks put US total within single digits of modern-day record (CIDRAP) Epidemiological Update – Measles in the Americas Region – 1 July 2025 (PAHO) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) New Mexico announces measles outbreak in a county detention facility (AP News) Weekly measles and rubella monitoring (Government of Canada) Measles vaccine recommendations from NYP (jpg) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Influenza Vaccination During Pregnancy and Infant Influenza in the First 6 Months of Life (Obstetrics & Gynecology) Influenza vaccination in Japanese children, 2024/25: Effectiveness of inactivated vaccine and limited use of newly introduced live-attenuated vaccine (Vaccine) FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Novel Drug Approvals for 2025 (FDA) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) Independent assessment of the origins of SARS‑CoV‑2(WHO) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Estimated 2023-2024 COVID-19 Vaccine Effectiveness in Adults (JAMA) RECOVID: Retrospective Observational Study of Renal Outcomes and Long-Term Mortality in Patients With COVID-19-Associated AKI, A Comparison Between Vaccinated and Unvaccinated Patients (Kidney Medicine) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Steroids,dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID COVID-19 and Cognitive Change in a Community-Based Cohort(JAMA) SARS-CoV-2 infection and new-onset type 1 diabetes in the post-acute period among children and young people in England(Diabetic Medicine) Reaching out to US house representative Letters read on TWiV 1232 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Today we discuss sex and vaccines, reality and renegades. First: men can no longer compete in women's sports—from Trump's Executive Order, to the NCAA's response, to William “Lia” Thomas having his records rescinded at Penn, reality is prevailing. Other evidence includes the UK Supreme Court declaring that “man” and “woman” refer to biological reality; and the U.S. Supreme Court writing an opinion that forcing LGBTQ+ books on children in public elementary schools is unconstitutional. Men cannot magically turn into women, nor boys into girls, no matter what they believe or are told. Then: from the ACIP (Advisory Committee on Immunization Practices) to Vinay Prasad's latest presentation at the FDA: the federal government is being populated by a combination of true renegades and middle ground scramblers who are dressed like renegades. A good toolkit for understanding how to make sense of the claims being made is necessary, and we all should be rooting for the renegades to win.*****Our sponsors:CrowdHealth: Pay for healthcare with crowdfunding instead of insurance. It's way better. Use code DarkHorse at JoinCrowdHealth.com to get 1st 3 months for $99/month.ARMRA Colostrum is an ancient bioactive whole food that can strengthen your immune system. Go to http://www.tryarmra.com/DARKHORSE to get 15% off your first order.Helix: Excellent, sleep-enhancing, American-made mattresses. Go to www.HelixSleep.com/DarkHorse for 27% Off - an offer exclusive for listeners of DarkHorse!*****Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.comHeather's newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.comOur book, A Hunter-Gatherer's Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org*****Mentioned in this episode:Trump's EO: https://www.whitehouse.gov/presidential-actions/2025/02/keeping-men-out-of-womens-sports/Paula Scanlan speaks about men in women's sports:https://x.com/xx_xyathletics/status/1940381615131332719U.K. Supreme Court: https://www.supremecourt.uk/cases/uksc-2024-0042The Lancet – sex isn't binary! https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00834-7/fulltextU.S. Supreme Court – Mahmoud vs Taylor: https://www.supremecourt.gov/opinions/24pdf/24-297_4f14.pdfWilliam Thomas in the record books: https://www.outkick.com/sports/lia-thomas-upenn-womens-swimming-record-books-updated-acknowledges-transgender-swimmer-noteRFK Jr on Tucker: https://www.youtube.com/watch?v=w_fzlwxJZAAACIP committee with Robert Malone and Retsef Levi: https://x.com/janjekielek/status/1939482343313453423Prasad on myocarditis: https://x.com/US_FDA/status/1940111214497210425Prasad makes full professor: https://x.com/bretweinstein/status/1554849287300792320Earlier clips of ZDogg and Prasad and Makary: https://x.com/alexandrosm/status/1574530850565558272Support the show

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world.Nicole Verdun has exited the FDA as CBER director, allowing Vinay Prasad to consolidate power within the agency. Prasad is seen as a stabilizing and trustworthy figure within the rapidly changing FDA, especially since the departure of Peter Marks in late March. Novavax is adapting to regulatory uncertainty following the delayed approval of its next-generation COVID-19 vaccine. The company is relying on agility and a diverse pipeline to navigate changing regulations. Additionally, the FDA has frozen trials shipping cells to countries like China due to new export control policies. Exemptions have allowed companies to ship biological materials overseas, but this practice is now being restricted. Zealand's GLP-1/GLP-2 drug has shown promising results in weight loss trials, with analysts believing there is potential for further improvement. Intellia Therapeutics aims to transform the lives of people with severe diseases through genome editing treatments. Overall, the biotech industry is facing various challenges and changes, requiring companies to stay adaptable and innovative.

The tragic death of a second non-ambulatory DMD patient treated with Sarepta's Elevidys gene therapy marks a turning point for the field and should drive all stakeholders to come together to figure out how to safely treat patients with this new modality. On the latest BioCentury This Week podcast, BioCentury's analysts discuss the opportunity FDA, companies and patient advocates have to share data and identify a safe path forward for the gene therapy field, both in DMD and beyond.The analysts also review promising early data for amylin agonists to treat obesity from Metsera and Eli Lilly, and discuss the vision for FDA's future laid out by Commissioner Marty Makary and CBER director Vinay Prasad. This episode of BioCentury This Week was sponsored by ICON Biotech.View full story: https://www.biocentury.com/article/656214#biotech #biopharma #pharma #lifescience #obesity #FDA #DMD00:01 - Sponsor Message: ICON Biotech01:19 - Gene Therapy Safety11:55 - Amylin in Obesity18:17 - FDA's FutureTo submit a question to BioCentury's editors, email the BioCentury This Week team at podcasts@biocentury.com.Reach us by sending a text

In this explosive episode, Jonathan Howard and Wendy Orent confront the accelerating dismantling of America's public health infrastructure. They begin with the NIH staff revolt—documented in the newly published Bethesda Declaration—and Jay Bhattacharya's astonishing lack of awareness during Senate testimony. From there, they shift to RFK Jr.'s controversial appointments to the CDC's Advisory Committee on Immunization Practices (ACIP), many of whom are tied to disinformation campaigns and anti-vaccine advocacy. The hosts expose the hypocrisy in the medical rhetoric of figures like Vinay Prasad, who once championed randomized controlled trials (RCTs) as the gold standard—until now. With the CDC gutted, the FDA undermined, and common sense replacing real science, they ask: how do we preserve truth in an age of weaponized misinformation? Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.  

Pink Sheet Executive Editor Derrick Gingery, Senior Writer Sarah Karlin-Smith, Senior Editor Sue Sutter and Editor-in-Chief Nielsen Hobbs discuss why seemingly routine comments from Vinay Prasad, director of the US Food and Drug Administration's Center for Biologics Evaluation and Research, that he would stay away from daily review decisions were notable (:26), as well as the impact of proposed FDA budget cuts by the White House and the House of Representatives (17:16). More On These Topics From The Pink Sheet Prasad Says Involvement In US FDA Product Approvals Will Mirror Prior CBER Directors: https://insights.citeline.com/pink-sheet/rare-diseases/prasad-says-involvement-in-us-fda-product-approvals-will-mirror-prior-cber-directors-KF4LJWX5U5DLBMSM6D4YFL7ZOA/ To Compete With China, US FDA Must Deregulate Early Gene Therapy Studies, CAR-T Inventor Says: https://insights.citeline.com/pink-sheet/advanced-technologies/cell-and-gene-therapies/to-compete-with-china-us-fda-must-deregulate-early-gene-therapy-studies-car-t-inventor-says-VDVXZGZIJZFHHNGGQXYILBI7RM/ FDA's FY 2026 Budget Request Lacks New Policy Proposals: https://insights.citeline.com/pink-sheet/legislation/fdas-fy-2026-budget-request-lacks-new-policy-proposals-WV3LE2AYBRAC7LIYJEU4WZDNGU/ User Fee-Funded Staff Would Drop In FY 2026 US FDA Budget: https://insights.citeline.com/pink-sheet/agency-leadership/us-fda/user-fee-funded-staff-would-drop-in-fy-2026-us-fda-budget-TQZMEB57V5GELNPMYGTY5BEGOY/ House Gives US FDA More Non-User Fee Funds Than Requested: https://insights.citeline.com/pink-sheet/pathways-and-standards/user-fees/house-gives-us-fda-more-non-user-fee-funds-than-requested-PCQZCBHOB5ARPICMJJQ6VYIJ5M/

Marty Makary and Vinay Prasad claim they're going to open the "black box" at the FDA, an agency they're now both employed at. So they started a podcast. It's not the first official FDA podcast, but it certainly fits into the contrarian ethos both men have cultivated since 2020. Derek and Julian listen in to see how much of that box is actually being opened. Learn more about your ad choices. Visit megaphone.fm/adchoices

We've been talking about RFK Jr for years, and even dedicated an entire chapter to him in our 2023 book—and we're going to keep covering him. Since his power and influence has only grown, and since he's now in charge of America's entire health apparatus, there's no way to avoid it. This week we catch up on the last few months of MAHA. Derek looks into why he believes Kennedy's apparatus, despite claims of being about health, is really a cover for Project 2025's deregulatory agenda. Julian discusses a recent paper published in the New England Journal of Medicine by Covid contrarians Marty Makary and Vinay Prasad, who now both work under Kennedy. Finally, Matthew will contemplate Kennedy's crude remarks on autism through the lens of disability politics. Show Notes What Has All This Restaurant Food Done to My Gut? Function Health is Another Theranosesque Scam MAHA's Goal Is Not Health: Robert Kennedy's movement promises more privatization RFK Jr. meets with health tech startups, most backed by Andreessen Horowitz COVID infection no longer gives lasting immunity Hybrid Immunity May Be the Key to Developing Better Vaccines Makary, Bhattacharya in New England Journal of Medicine Consequences of Work Requirements in Arkansas: Two-Year Impacts on Coverage, Employment, and Affordability of Care  Concerns About ABA-Based Intervention: An Evaluation and Recommendations - PMC  Adler-Bolton, Beatrice, and Artie Vierkant. 2022. Health Communism: A Surplus Manifesto. Verso Books. SURPLUS. Adler-Bolton, The New Inquiry. October 18, 2022.  Extractive Abandonment - Stimpunks Foundation  Social and medical models of disability and mental health: evolution and renewal - PMC Learn more about your ad choices. Visit megaphone.fm/adchoices

Subscribe on Patreon and hear this week's full patron-exclusive episode here: https://www.patreon.com/posts/129947873 Beatrice and Artie discuss the “GOP Murder Bill” just passed in the House of Representatives, with a particular focus on why adding work requirements to Medicaid is so dangerous, and how brazen the attacks on trans care are under the bill. Then we discuss Vinay Prasad and Marty Makary's attempts to use the FDA to make it impossible to get a covid vaccine. Runtime 1:26:00 Note: We're back! Thank you to everyone for all the well wishes and many kind messages during our parental leave. We have a lot coming together soon processing current events and reacting to some big developments that happened while we were away. As we ramp production back up we'll be prioritizing the patron feed first to make sure patrons get a full new episode every week. Get Health Communism here: www.versobooks.com/books/4081-health-communism Find Jules' new book here: https://www.versobooks.com/products/3054-a-short-history-of-trans-misogyny

Is your immune system strong enough for politics? In a reversal of federal public health policy, the Trump administration announced it will restrict access to seasonal COVID-19 shots, reserving them mainly for seniors and high-risk individuals. That's despite the fact that COVID-19 claimed more than 47,000 American lives last year, including 231 children. Under new FDA guidance backed by Health Secretary Robert F. Kennedy Jr., most healthy Americans under 65 will not be eligible for updated boosters unless new clinical trials prove they're necessary. That means, for the first time, your access to a shot could depend on whether you're deemed high-risk. The new policy reflects a growing movement inside the administration to pull back on vaccines, especially for the young and healthy. Dr. Vinay Prasad, now the FDA's top vaccine official, described the decision as a compromise. Critics call the policy dangerous. Learn more about your ad choices. Visit megaphone.fm/adchoices

Is the “poop pill” a possible treatment for small intestinal bacterial overgrowth (SIBO)? Pro-mask, pro-lockdown, pro-vax words come back to haunt their authors as Covid response critics appointed to key HHS positions; MAHA influencer Dr. Casey Means replaces original Surgeon General nominee; Rating Trump's new vaccine czar, oncologist Vinay Prasad; Is Laetrile effective for cancer? If you're eating a diet rich in fruits and vegetables, do you still need probiotics? Researchers tap an unusual source for antivenom against deadly snakebites—a snake handler who's survived multiple poisonings.

Dr. Jonathan Howard and Wendy Orent unpack the deep ironies and ethical contradictions behind recent appointments at the NIH and FDA. From once-demanded randomized controlled trials now deemed “not always necessary,” to the political operatives now at the helm of America's public health infrastructure, the duo explores how power rewrites principles. They dissect statements from RFK Jr., Vinay Prasad, and Jay Bhattacharya, drawing attention to the chilling real-world consequences of politicized medicine—especially for vaccines and children's health.   Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.  

America Out Loud PULSE with Dr. Vaughn & Dr. Tankersley – If the news is accurate that the nominee for Surgeon General, Casey Means, is pregnant, I hope she avoids the COVID shot for her child and tells the world why. The new FDA vaccine director, Dr. Vinay Prasad, replaces the fraudulent Peter Marks and is immediately called an ‘anti-vaxxer' despite decades of giving them to his patients...

America Out Loud PULSE with Dr. Vaughn & Dr. Tankersley – If the news is accurate that the nominee for Surgeon General, Casey Means, is pregnant, I hope she avoids the COVID shot for her child and tells the world why. The new FDA vaccine director, Dr. Vinay Prasad, replaces the fraudulent Peter Marks and is immediately called an ‘anti-vaxxer' despite decades of giving them to his patients...

Biopharmas developing therapies for obesity are looking to a future where the quality of weight loss matters as much as the quantity — what targets and programs could help realize that vision? On the latest BioCentury This Week podcast, BioCentury's editors discuss the signaling pathways that may exclusively target fat mass while preserving, or even increasing, lean mass — and which companies are playing in the space.The editors also assess what Vinay Prasad's past comments say about how he might lead FDA's Center for Biologics Evaluation and Research (CBER) — and examine how investors are evaluating the possibility that he might move the bar for regulatory approvals. The team then introduces the first in a new BioCentury series, with a look at a Literature Dive into ovarian cancer “atlases” — large-scale molecular profiling studies that point to predictive signatures and patient stratification strategies. This episode was sponsored by Jeito Capital.View full story: https://www.biocentury.com/article/655898#biotech #biopharma #pharma #obesity #FDA #CBER #LifeScience #OvarianCancer00:01 - Sponsor Message: Jeito Capital03:22 - Obesity: Quality over Quantity15:47 - Prasad at FDA27:58 - Ovarian Cancer AtlasesTo submit a question to BioCentury's editors, email the BioCentury This Week team at podcasts@biocentury.com.Reach us by sending a text

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.The White House has announced a new drug pricing policy that includes the revival of the most favored nations rule and extends to the private markets, leveraging the patent system, drug importation, and more. Meanwhile, Lilly's Zepbound has been found to have a superior benefit-risk ratio compared to Novo's Wegovy, BMS and Sanofi settle a Plavix lawsuit with Hawaii for $700 million, and biopharma companies are focusing on developing a cure for HIV as federal funding for related research is being cut. Sino Biological offers comprehensive solutions for autoimmune diseases, and Roche promises a $300 million investment in China production after a multibillion-dollar investment in the US. On the other hand, Lexeo and IGM have both announced significant layoffs. Novartis CEO has expressed concerns about Trump's pricing controls.Funding for HIV-related research and infrastructure is being cut by the Trump administration, leading biopharma companies like Gilead and Immunocore to focus on finding a cure for HIV. In the field of neurology, there is a need for more precise diagnostic tools to effectively treat neurodegenerative conditions. The new HHS vaccine requirement has been criticized by leading vaccine physician Paul Offit as potentially being anti-vaccine activism disguised as policy. Companies like Novartis, Bayer, and AstraZeneca are exploring new indications and innovations in radiopharmaceuticals, hoping to capitalize on a market that could reach $16 billion by 2033. The FDA has faced delays in reviewing certain drugs, while biotech stocks have fallen after the appointment of Vinay Prasad to succeed Marks at CBER. Vertex has decided to abandon AAV in the gene therapy space.Upcoming events include a webinar on surviving and thriving in the biotech downturn. Job opportunities in the biopharma industry include positions at Takeda, Daiichi Sankyo, and AbbVie. Heather McKenzie, senior editor at BioSpace, is open to suggestions for future coverage topics in neuroscience, oncology, cell & gene therapy, metabolic, or other areas.

Dr. Jonathan Howard and Wendy Orent examine the alarming elevation of wellness influencer Casey Means as Surgeon General nominee, despite lacking a medical license or conventional medical credibility. They delve into Vinay Prasad's appointment as head of vaccine regulation, scrutinizing his past critiques of RCT deficiencies—and the impossible standards he now sets for himself. The episode also investigates the troubling rise of an autism registry, likened to authoritarian categorization, and NIH's internal collapse under Jay Bhattacharya, whose leadership is marked by mass layoffs and denial of responsibility. With science policy veering into cronyism, dismantling, and performative governance, the episode argues that we're witnessing a historic erosion of public health leadership—led not by scientists, but social media provocateurs. Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.  The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information. The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content. The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content. Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer. Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.

In Episode 42 of MAHA News, Jordan Sather and Nate Prince tackle the explosive drama surrounding Trump's new Surgeon General nominee, Dr. Casey Means. The appointment has triggered fierce infighting across the MAHA and MAGA camps, with accusations flying over her lack of an active medical license, unfinished residency, and New Age wellness views. But Jordan and Nate cut through the hysteria, pointing out that her holistic, metabolic-based approach is exactly what the country needs, and that most critics are conveniently ignoring the total clownery of past Surgeon Generals. RFK Jr. weighs in with full-throated support for Means, denouncing coordinated smear campaigns by social media influencers, including Nicole Shanahan and Laura Loomer, whose emotional meltdowns and wild accusations get put under the microscope. The hosts also highlight RFK's game-changing appointments, like Vinay Prasad taking over FDA vaccine oversight, and his damning claim that the Biden-era HHS was complicit in the trafficking of over 300,000 missing children. The episode hits on Florida's symbolic geoengineering ban, the federal lab sabotage in Frederick, MD, and a disturbing WHO study linking cell phone radiation to cancer. Other hot topics include RFK's federal gain-of-function research ban, placebo testing for vaccines, fluoride deception in kids' toothpaste, and Tyson Foods' public relations pivot. With humor, clarity, and a side of righteous indignation, Jordan and Nate strip away the media spin to expose who's real, who's a plant, and what it all means for the future of health freedom.

Pink Sheet Executive Editor Derrick Gingery, Senior Editor Sue Sutter and Editor-in-Chief Nielsen Hobbs consider early excitement and concern about Vinay Prasad's potential impact on product development as director of the US Food and Drug Administration's Center for Biologics Evaluation and Research (:20). They also consider the consequences of the FDA missing product-specific guidance publication deadlines (14:59) and its potential impact on the upcoming user fee reauthorization negotiations (20:00). More On These Topics From The Pink Sheet Tougher Approval Standards May Follow Vinay Prasad's Appointment To Lead US FDA's CBER: https://insights.citeline.com/pink-sheet/agency-leadership/us-fda/tougher-approval-standards-may-follow-vinay-prasads-appointment-to-lead-us-fdas-cber-WEULXI5EJRE43BWU752PGDGE44/ US FDA Guidance Roadblock: Writing Continues, But Publication Has Slowed Or Stopped: https://insights.citeline.com/pink-sheet/biosimilars-and-generics/generics/us-fda-guidance-roadblock-writing-continues-but-publication-has-slowed-or-stopped-TZF4DMPEMVHT3JJPRUX7LJJIHU/

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world. Takeda's $30 billion investment in the U.S. is making headlines, along with their opposition to Trump's proposal on drug prices. The FDA's appointment of Vinay Prasad is stirring up mixed reactions within the industry. On another note, Lilly's legal victory against compounders, Novavax's growing sales, and Gilead's significant investment in U.S. manufacturing are all key developments. The FDA vaccine advisors are gearing up for a meeting to discuss COVID-19 updates, while Vor Bio is seeking an exit due to funding challenges. Biotech stocks took a hit following Prasad's appointment to lead CBER, highlighting the industry's current challenges including vaccine hesitancy and job market struggles.

Howie and Harlan are joined by Thomas Gill, a Yale geriatrician whose research tracks the factors that contribute to disability in older adults—and those that support continued independence. And they discuss the contrarian tapped to evaluate vaccines at the FDA, allegations of kickbacks against insurers, and the potential end of a loophole that has allowed states to collect additional Medicaid funding.  Links: Vinay Prasad at the FDA “Vinay Prasad tapped to run FDA center that regulates vaccines, gene therapies” “Vinay Prasad, in his own words, outlines the philosophy he'll bring to the FDA” “Peter Marks, FDA's top vaccine regulator, forced out” Howard Forman on LinkedIn on Vinay Prasad's Appointment Vinay Prasad's Substack Insurance News “Justice Department Sues Big Medicare Insurers Alleging Kickbacks” “Aetna to exit the ACA exchanges in 2026” “What Aetna quitting the exchanges says about the exchanges” ”CVS to boost access to Novo Nordisk's weight loss treatment Wegovy for patients on its drug plans” Thomas Gill Statista: Share of old age population (65 years and older) in the total U.S. population from 1950 to 2050 Thomas Gill: “A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study” Thomas Gill: “A Program to Prevent Functional Decline in Physically Frail, Elderly Persons Who Live at Home” “Prehabilitation for Patients Undergoing Orthopedic Surgery: A Systematic Review and Meta-analysis” “Allostatic Load: Importance, Markers, and Score Determination in Minority and Disparity Populations” “Cohort Profile: The Precipitating Events Project (PEP Study)” “In Memoriam: Yale Expert in Clinical Research Methods, Alvan R. Feinstein” Medicaid Cuts “Putting $880 Billion in Potential Federal Medicaid Cuts in Context of State Budgets and Coverage” “Republicans are running out of ways to cut Medicaid as moderates and hard-liners clash” “G.O.P. Targets a Medicaid Loophole Used by 49 States to Grab Federal Money” Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Novo Nordisk predicts a brighter future for Wegovy with the end of the semaglutide shortage, but analysts remain skeptical as Eli Lilly's Zepbound gains ground in sales. The new HHS vaccine requirement has raised questions about its true intentions, with leading vaccine physician Paul Offit criticizing the lack of clarity. Meanwhile, pharmaceutical imports from Ireland are on the rise, biotech stocks fell after Vinay Prasad was named to succeed Marks at CBER, and Lotte Biologics' ADC facility in Syracuse offers end-to-end services for antibody manufacturing. CRISPR's Casgevy is gaining traction with more gene therapy proof of concept expected in 2025, impacting M&A and IPOs in the biotech industry. Summit Pharmaceuticals is nearing the first global phase III data for Keytruda, set to lose exclusivity in 2028 and potentially face competition from biosimilars. A report suggests that low-price drug nations are benefiting from US innovation, undervaluing innovative medicines by 90%. VC financing in biopharma declined by 20% in Q1, but megarounds kept the median deal size high. M&A and IPOs faced challenges due to policy issues, leading to an increase in licensing deals. Novo vows to improve market access for Wegovy, while Trump orders FDA to ease US plant expansion and increase inspections of foreign facilities. BMS pledges a $40 billion investment in the US, Novartis makes M&A moves, and Lilly remains unfazed by CVS's decision to side with Novo in the obesity market battle. Some drugmakers are stockpiling products in the US amid Trump's trade war. NGM terminates half of its staff as its lead asset moves through a registrational study. Job opportunities in clinical quality assurance audit, RBQM central statistical monitoring, and field medical capabilities are available.

Dr. Jonathan Howard and Wendy Orent return to discuss the alarming direction of U.S. public health, focusing on RFK Jr.'s misinformation campaign about vaccines, the threat of COVID booster access disappearing under political pressure, and the erosion of CDC authority.  They critique the hypocrisy of figures like Marty Makary and Vinay Prasad who now call for new randomized controlled trials while simultaneously undercutting access to vaccines.  The conversation also highlights the troubling revisionist COVID narratives being pushed by mainstream journalists and the dangerous implications of gutting pandemic protections—particularly for vulnerable groups.   Connect with us further on https://sciencebasedmedicine.org/author/jonathanhoward/  The Fine Print The content presented in the "We Want Them Infected" Podcast and associated book is intended for informational and educational purposes only.    The views and opinions expressed by the speakers, hosts, and guests on the podcast do not necessarily reflect the views of the creators, producers, or distributors. The information provided in this podcast should not be considered as a substitute for professional medical, scientific, or legal advice. Listeners and readers are encouraged to consult with relevant experts and authorities for specific guidance and information.   The creators of the podcast and book have made reasonable efforts to ensure that the information provided is accurate and up to date. However, as the field of medical science and the understanding of the COVID-19 pandemic continue to evolve, there may be new developments and insights that are not covered in this content.   The creators are not responsible for any errors or omissions in the content or for any actions taken based on the information provided. They disclaim any liability for any loss, injury, or damage incurred by individuals who rely on the content.   Listeners and readers are urged to use their judgment and conduct their own research when interpreting the information presented in the "We Want Them Infected" podcast and book. It is essential to stay informed about the latest updates, guidelines, and recommendations related to COVID-19 and vaccination from reputable sources, such as government health agencies and medical professionals. By accessing and using the content, you acknowledge and accept the terms of this disclaimer.   Please consult with appropriate experts and authorities for specific guidance on matters related to health, science, and the COVID-19 pandemic.