In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including o…
American College of Cardiology

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Commentary by Dr. Jian'an Wang.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Accelerometer-Measured Sedentary Behavior, Future Disease, and Cardiovascular-Kidney-Metabolic Health.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Differential Association Between Surrounding Greenness and Mortality in Individuals With Coronary Heart Disease.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sex Differences in Cardiac Involvement in Adults With Myotonic Dystrophy Type 1: A Multicenter Study.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Characteristics, Management, and Outcomes of Diabetes Subtypes in Patients With Cardiogenic Shock: A Nationwide Analysis.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Comparison of Microcirculation in Chronic Heart Failure, Cardiogenic Shock, LVAD, and Heart Transplantation.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Early Diagnosis of ATTR-CM by Age- and Carpal Tunnel Biopsy-Guided Screening.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Generalizability of Landmark Temporary MCS Device Trials: Insights From the CSWG Registry.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Outcomes of Targeted Volume Overload Management in Patients With Severe Aortic Stenosis.

Dr. Mohamad Alkhouli speaks with Dr. Wayne Batchelor about what leadership truly means for mid‑career interventional cardiologists and whether pursuing an MBA adds value. Dr. Batchelor highlights trust, communication, and business fluency as essential skills for physician leaders navigating increasingly complex healthcare systems.

Dr. Mohamad Alkhouli and Dr. Kirk Garratt discuss leadership in interventional cardiology, highlighting the importance of empathy, communication, and advocacy alongside clinical expertise. Dr. Garratt encourages physicians to intentionally develop leadership skills—through training or experience—as healthcare systems become more complex.

In this conversation, Dr. Mohamad Alkhouli speaks with Dr. Abbott about her leadership journey in interventional cardiology, focusing on how curiosity, mentorship, and skill development organically lead to meaningful leadership roles. Dr. Abbott shares practical insights on motivating teams, navigating complex healthcare systems, and whether formal business training such as an MBA is necessary for physician leaders.

Dr. Mohamad Alkhouli and Dr. Deepak Bhatt discuss leadership development in interventional cardiology and the value of pursuing an executive MBA mid‑career. Dr. Bhatt shares insights on how business training—from finance to leadership and strategy—can help physicians navigate increasingly complex healthcare systems and become more effective stewards of patient care and resources.

Commentary by Dr. Katsuhiko Imai.

Commentary by Dr. Satoshi Shizuta.

Commentary by Dr. Deep Chandh Raja.

Commentary by Dr. Leandra Serio.

Deputy Editor Kenneth Ellenbogen presents an in‑depth discussion of the study "Long PR Interval Leads to Atrial Remodeling, Fibrosis and Inducible Atrial Fibrillation in a Swine Model." In this episode, Dr. Ellenbogen walks listeners through how prolonged atrioventricular conduction can drive structural and electrical remodeling in the atria, leading to fibrosis and increased susceptibility to atrial fibrillation. He highlights the significance of these findings for understanding AF pathophysiology and considers how this preclinical model may inform future prevention and treatment strategies.

In this podcast, Francis Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a novel pulsed field ablation–based endocardial strategy for ventricular tachycardia in patients with arrhythmogenic right ventricular cardiomyopathy. The paper presents an early consecutive experience demonstrating the feasibility, acute effectiveness, and safety of PFA for VT without the need for epicardial access. Dr. Marchlinski highlights the clinical implications of this approach and how tissue-selective, nonthermal energy may expand treatment options for this challenging patient population.

In this podcast, Francis Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a large multicenter study evaluating the incidence and clinical significance of aortic regurgitation following mapping and ablation of ventricular arrhythmias in the aortic cusps and commissures. Drawing on contemporary data from four high‑volume centers, the paper provides important reassurance regarding the safety of aortic cusp ablation, demonstrating that clinically significant aortic regurgitation is rare and infrequently progressive. Dr. Marchlinski highlights the key findings, procedural considerations, and implications for everyday practice in ventricular arrhythmia ablation.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Associations of Socioeconomic Status With Cardiorenal Metabolic Multimorbidity: Evidence From the UK Biobank Cohort.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Dietary Sodium Intake and Risk of Incident Heart Failure in the Southern Community Cohort Study.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Coronary Sinus Reduction for REDUCER-I Patients With Refractory Angina and Angiographically Nonobstructive Coronary Artery Disease.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Remote Management of Patients With Heart Failure in Medically Underserved Areas.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Development of a Predictive Tool in Patients With High Pretest Probability for Transthyretin Amyloid Cardiomyopathy.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Valvular Heart Diseases in Swedish Males and Females: A National Cohort Study.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Cardiovascular-Kidney-Metabolic Syndrome and Life Expectancy in U.S. Adults.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on 10-Year Excess Mortality After First-Time Non–ST-Segment Elevation Myocardial Infarction: The Western Denmark Heart Registry.

Dr. Michel G. Khouri reviews a landmark study examining patients with AL amyloidosis who achieved a complete cardiac biomarker response, highlighting profound improvements in cardiac structure, function, and long-term survival that rival the general population. The discussion underscores the transformative impact of early diagnosis and modern plasma cell–directed therapies, while reminding clinicians that ongoing multidisciplinary cardiac care remains essential even after sustained cardiac remission.

Dr. Qun Shao discusses two multicenter studies evaluating cardiovascular adverse events associated with bispecific T‑cell engager therapies. Drawing on data from over 700 patients, the episode highlights the incidence, predictors, and clinical impact of cardiovascular complications, emphasizing the importance of baseline risk assessment, targeted monitoring, and multidisciplinary management as use of these therapies continues to expand.

Research fellow, Adrian Chen, discusses a multicenter study evaluating myocardial PD‑L1 expression as a prognostic biomarker in immune checkpoint inhibitor–associated myocarditis. The conversation highlights how elevated myocardial PD‑L1 identifies patients at markedly higher risk for early adverse cardiac events and explores its potential role in improving risk stratification and guiding earlier, more aggressive therapy in this high‑risk population.