JACC Speciality Journals

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In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including o…

American College of Cardiology


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    Latest episodes from JACC Speciality Journals

    Use of Electrocardiograms to Identify Coronary Artery Disease: Cross-Validation of an Artificial Intelligence Model | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:28


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Use of Electrocardiograms to Identify Coronary Artery Disease: Cross-Validation of an Artificial Intelligence Model.

    cross model artificial intelligence identify validation advances arteries podcast editor coronary artery disease jacc
    VExUS Point-of-Care Ultrasound Tool to Detect Changes in Volume Status: A Prospective Observational Study | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:12


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on VExUS Point-of-Care Ultrasound Tool to Detect Changes in Volume Status: A Prospective Observational Study.

    study tool status advances prospective detect ultrasounds podcast editor observational studies care ultrasound jacc
    Comparative Strategies to Overcome Diuretic Resistance in Heart Failure: A Network Meta-Analysis | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 3:07


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Comparative Strategies to Overcome Diuretic Resistance in Heart Failure: A Network Meta-Analysis.

    strategy overcome resistance advances comparative heart failure podcast editor jacc diuretic network meta analysis
    Prehabilitation in Patients Undergoing Cardiac Procedures: A Systematic Review and Meta-Analysis | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:36


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prehabilitation in Patients Undergoing Cardiac Procedures: A Systematic Review and Meta-Analysis.

    patients advances procedures systematic cardiac meta analysis undergoing podcast editor jacc prehabilitation
    Pregnancy in Women With Impaired Left Ventricular Function: Data From ROPAC | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:32


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Pregnancy in Women With Impaired Left Ventricular Function: Data From ROPAC.

    women data left pregnancy function advances impaired podcast editor ventricular jacc ropac
    Cardiac Rehabilitation Utilization Among Veterans: A Sex-Based Analysis | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:50


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Cardiac Rehabilitation Utilization Among Veterans: A Sex-Based Analysis.

    veterans advances utilization podcast editor cardiac rehabilitation jacc
    Frailty Status Predicts Adverse Outcomes in Ambulatory Heart Failure With Preserved Ejection Fraction | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:50


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Frailty Status Predicts Adverse Outcomes in Ambulatory Heart Failure With Preserved Ejection Fraction.

    status advances predicts preserved heart failure ejection frailty fraction ambulatory podcast editor jacc adverse outcomes
    Intracoronary Vasoactive Therapy for No-Reflow During Primary PCI: A Network Meta-Analysis of Randomized Trials | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:20


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Intracoronary Vasoactive Therapy for No-Reflow During Primary PCI: A Network Meta-Analysis of Randomized Trials.

    therapy trials primary advances randomized podcast editor jacc network meta analysis reflow
    Mechanical Debulking in Calcified Arteries: ROLLING STONE Study | JACC: Cardiovascular Interventions

    Play Episode Listen Later Mar 24, 2026 14:29


    Dr Aaysha Cader, Social media editor for JACC Interventions discusses the paper, Intravascular Lithotripsy or Mechanical Debulking in Complex Calcified Coronary Arteries: Multicenter, Prospective ROLLING STONE Study, with its first author, Dr Enrico Cerrato.

    social study rolling stones mechanical interventions cardiovascular arteries jacc
    TRANScatheter edge-to-edge rePAir for SAM related mitral REgurgitation in patieNTs with HCM. The TRANSPARENT registry | JACC: Cardiovascular Interventions

    Play Episode Listen Later Mar 20, 2026 14:20


    Dr Aaysha Cader, Social media editor for JACC Interventions discusses the paper, Transcatheter Edge-to-Edge Repair for SAM-Related Mitral Regurgitation in Patients With HCM: The TRANSPARENT Registry, with Professor Luca Testa.

    social patients repair transparent interventions cardiovascular registry regurgitation mitral jacc transcatheter
    Comparing High-Density Electroanatomical Mapping and MRI: a step forward in myocardial characterization in non-ischemic cardiomyopathy

    Play Episode Listen Later Mar 20, 2026 4:30


    Dr. Francis Marchlinski highlights new research comparing high‑density electroanatomical mapping with cardiac MRI in non‑ischemic cardiomyopathy. He explains how omnipolar mapping more accurately reflects MRI‑defined scar patterns—especially in deeper layers—and why this technology may offer a valuable alternative when MRI is limited or unavailable. A concise look at emerging tools reshaping arrhythmic risk assessment.

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    Predictors of Bleeding Complications After Extracorporeal Cardiopulmonary Resuscitation: Insights From the SAVE-J II Study | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 2:59


    Commentary by Dr. Qin LU.

    study commentary bleeding complications predictors jacc extracorporeal cardiopulmonary resuscitation
    Hemolysis After TAVR Using the Fifth-Generation Balloon-Expandable Valve: Comparison With the Third-Generation Valve | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 3:51


    Commentary by Dr. Matteo Sturla

    comparison commentary balloon valve third generation tavr fifth generation jacc expandable
    Diabetes and ALDH2 Gene Polymorphism on Post-Ablation Atrial Fibrillation Recurrence | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 2:59


    Commentary by Dr. Takeshi Aiba

    diabetes commentary atrial fibrillation recurrence ablation polymorphism jacc
    Brief Introduction - Predictors of Bleeding Complications After Extracorporeal Cardiopulmonary Resuscitation: Insights From the SAVE-J II Study | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:23


    Commentary by Dr.  Jian'an Wang.

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    Brief Introduction - Suitability for Transcarotid Transcatheter Aortic Valve Replacement in the Japanese Population | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:00


    Commentary by Dr.  Jian'an Wang.

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    Brief Introduction - Hemolysis After TAVR Using the Fifth-Generation Balloon-Expandable Valve: Comparison With the Third-Generation Valve | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:13


    Commentary by Dr.  Jian'an Wang

    comparison commentary wang balloon valve brief introduction third generation jian tavr fifth generation jacc expandable
    Brief Introduction - Diabetes and ALDH2 Gene Polymorphism on Post-Ablation Atrial Fibrillation Recurrence | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:17


    Commentary by Dr.  Jian'an Wang

    diabetes commentary wang atrial fibrillation brief introduction recurrence ablation jian polymorphism jacc
    Brief Introduction - Phase 3, Open-Label Multicenter Study of Sotatercept in Japanese Participants With Pulmonary Arterial Hypertension | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:25


    Commentary by Dr.  Jian'an Wang

    japanese study commentary wang phase 3 brief introduction jian jacc pulmonary arterial hypertension open label
    Brief Introduction - Asia at the Epicentre of the Global Cardiometabolic Shift | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:16


    Commentary by Dr.  Jian'an Wang

    global shift commentary wang brief introduction jian epicentre jacc
    Brief Introduction - Medication Adherence and Antithrombotic Therapy Outcomes: Insights From a Post Hoc Analysis of the AFIRE Trial | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:20


    Commentary by Dr.  Jian'an Wang

    trial commentary outcomes medications wang brief introduction jian afire medication adherence jacc post hoc antithrombotic therapy
    Brief Introduction - Cholesterol-Inflammation Fusion Hypothesis in Atherosclerosis: An Evolving Paradigm in Pathogenesis and Therapy | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:31


    Commentary by Dr.  Jian'an Wang

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    March 2026 Issue Summary | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 11:39


    Audio Summary of the March 2026 Issue of JACC: Asia, by Dr. Jian'an Wang.

    wang jian jacc audio summary
    Phase 3, Open-Label Multicenter Study of Sotatercept in Japanese Participants With Pulmonary Arterial Hypertension (copy) | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 3:41


    Commentary by Dr. Yunshan Cao

    japanese study commentary copy phase 3 jacc pulmonary arterial hypertension open label
    Identifying Palliative Care Competencies for Cardiology Fellowship Training: A National Delphi Consensus Study | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 8:56


    Candice K. Silversides, MD, FACC, Editor-in-Chief of JACC: Advances, interviews authors Sarah Godfrey MD, MPH, FACC and Caroline L. Doherty DNP, AGACNP-BC, FACC about their paper, "Identifying Palliative Care Competencies for Cardiology Fellowship Training: A National Delphi Consensus Study" published in the February 2026 issue of the Journal.

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    Prognostic Value of CMR-Derived Left Ventricular Filling Pressure in Broad Referral Populations | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:43


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prognostic Value of CMR-Derived Left Ventricular Filling Pressure in Broad Referral Populations.

    left pressure filling advances broad referral populations derived podcast editor ventricular jacc prognostic value
    Atrial Fibrillation/Flutter in Transthyretin Cardiac Amyloidosis: Prevalence, Incidence, Clinical Predictors, and Effect of Tafamidis | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 3:03


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Atrial Fibrillation/Flutter in Transthyretin Cardiac Amyloidosis: Prevalence, Incidence, Clinical Predictors, and Effect of Tafamidis.

    clinical advances cardiac prevalence predictors flutter incidence atrial fibrillation podcast editor amyloidosis jacc transthyretin tafamidis
    A 4-Decade Population-Based Registry of Thoracic Aortic Dissection Causing Sudden Death in the Young | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 3:13


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on A 4-Decade Population-Based Registry of Thoracic Aortic Dissection Causing Sudden Death in the Young.

    young decade population causing advances registry sudden death thoracic podcast editor aortic dissection jacc
    Long-Term Cardiovascular Health Trajectories Associated With Cardiovascular Disease and Mortality in Older Adults | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:33


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Cardiovascular Health Trajectories Associated With Cardiovascular Disease and Mortality in Older Adults.

    long term advances mortality older adults cardiovascular diseases cardiovascular health trajectories podcast editor jacc
    Risk Score Development to Predict Postpartum Cardiovascular Disease Incorporating Pregnancy and Nonpregnancy Factors: A Canada-Wide Study | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:49


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Risk Score Development to Predict Postpartum Cardiovascular Disease Incorporating Pregnancy and Nonpregnancy Factors: A Canada-Wide Study.

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    Increasing Awareness and Reducing Occupational Hazards in the Cardiac Catheterization and Electrophysiology Laboratories: Working to Eliminate Lead and Complications of Radiation in Cardiovascular Team Study | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:45


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Increasing Awareness and Reducing Occupational Hazards in the Cardiac Catheterization and Electrophysiology Laboratories: Working to Eliminate Lead and Complications of Radiation in Cardiovascular Team Study.

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    Multisite, External Validation of an AI-Enabled ECG Algorithm for Detection of Low Ejection Fraction | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:19


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Multisite, External Validation of an AI-Enabled ECG Algorithm for Detection of Low Ejection Fraction.

    algorithms external validation advances detection enabled ejection fraction podcast editor multisite jacc
    Device-Removal, Reinfection, and Mortality After Staphylococcus aureus Bacteremia in Patients With Cardiac Implantable Electronic Devices | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:57


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Device-Removal, Reinfection, and Mortality After Staphylococcus aureus Bacteremia in Patients With Cardiac Implantable Electronic Devices.

    patients advances removal mortality cardiac podcast editor implantable electronic devices reinfection jacc staphylococcus aureus
    The Transmural Activation Interval in Dilated Cardiomyopathy: A New Mapping Tool for Intramural VT Substrates | JACC: Clinical Electrophysiology

    Play Episode Listen Later Feb 18, 2026 4:19


    Commentary by JACC: Clinical Electrophysiology Deputy Editor Francis Marchlinski, MD.

    md tool commentary mapping activation interval substrate intramural dilated cardiomyopathy jacc clinical electrophysiology
    Polygenic risk for cardiometabolic and cardiovascular disease in a multi-ethnic cohort of breast cancer survivors | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 3:07


    Polygenic risk scores showed associations with several cardiometabolic outcomes in breast cancer survivors but did not improve prediction beyond traditional clinical factors. Their performance varied across ancestry groups and was weakened in patients exposed to cardiotoxic therapies, highlighting limits of current genetic risk tools.

    risk ethnic cohorts cardiovascular diseases breast cancer survivors jacc polygenic
    Atrial Fibrillation Following Autologous Stem Cell Transplantation in Multiple Myeloma: Incidence, Predictors, and Prognostic Impact | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 3:28


    This study of 801 multiple myeloma patients found that atrial fibrillation occurred in 5.5% within 90 days after autologous stem cell transplantation—nearly double previously reported rates—indicating disease‑specific risks. AF strongly predicted mortality from non‑relapse causes and may serve as a marker of physiological vulnerability, emphasizing the value of expanded pre‑transplant cardiac assessment and monitoring.

    af stem cells predictors transplantation incidence atrial fibrillation multiple myeloma prognostic autologous jacc
    CRISPR/Cas9 screens implicate RARA and SPNS1 in doxorubicin cardiotoxicity | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 3:15


    Researchers used genome‑wide CRISPR/Cas9 loss‑of‑function screens in cardiomyocytes to identify RARA and SPNS1 as key modulators of doxorubicin cardiotoxicity, highlighting pathways that influence both injury susceptibility and intracellular drug handling. Activation of RARA reduced toxicity without impairing anticancer effects, while SPNS1 loss caused harmful drug accumulation, offering new mechanistic insights and potential therapeutic targets.

    researchers activation screens rara crispr cas9 jacc doxorubicin
    Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 3:21


    This study analyzes over 2,600 transthyretin V142I variant carriers in the Million Veteran Program and finds significantly elevated risks of heart failure, cardiomyopathy, arrhythmias, neuropathy, and musculoskeletal complications compared with matched controls. Despite these risks, amyloidosis was rarely diagnosed clinically, underscoring major gaps in recognition and the need for earlier identification and multidisciplinary intervention.

    risk veterans manifestation variant mortality systemic carriers jacc transthyretin
    February 2026 Full Issue Summary | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 14:33


    JACC: CardioOncology Volume 8 Issue 1 Full Issue Summary with Introduction by Dr. Bonnie Ky, Editor-in-Chief

    jacc
    Genotype-Guided vs. Conventional P2Y12 Inhibitors in ACS | JACC: CV Interventions | JACC: Cardiovascular Interventions

    Play Episode Listen Later Feb 13, 2026 6:47


    Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Mattio Galli, MD, PhD, discuss a recently published original research paper analyzing the role of genotype-guided escalation or de-escalation of antiplatelet therapy in acute coronary syndrome (ACS).

    phd md guided conventional interventions cardiovascular acs inhibitors genotype social media editor jacc p2y12
    Bleeding in infarct related cardiogenic shock: DanGer Shock substudy | JACC: CV Interventions | JACC: Cardiovascular Interventions

    Play Episode Listen Later Feb 13, 2026 6:29


    Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Rikke Sørensen, MD, PhD, discuss a recently published original research paper from DanGer Shock substudy analyzing the bleeding events in patients with infarct related cardiogenic shock.

    phd md danger shock bleeding interventions cardiovascular social media editor cardiogenic jacc
    Brief Introduction - Sex Disparities in Ischemic Heart Disease in South Asia: The Role of Dietary Factors

    Play Episode Listen Later Feb 6, 2026 0:57


    Commentary by Dr.  Jian'an Wang.

    commentary factors wang south asia dietary disparities brief introduction jian ischemic heart disease
    Brief Introduction - Risk Prediction Models of Cardiotoxicity in Patients With Breast Cancer: Multicenter Prospective CHECK HEART-BC Study | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 0:44


    Commentary by Dr.  Jian'an Wang.

    predictions risk study patients commentary models breast cancer wang prospective brief introduction jian jacc
    Brief Introduction - Interconnected Pathways and Therapeutic Implications for Cardiovascular Aging and Diseases | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 0:34


    Commentary by Dr.  Jian'an Wang.

    disease commentary implications pathways wang therapeutic cardiovascular interconnected brief introduction jian jacc
    Brief Introduction - Sleep Patterns and Blood Pressure Among Chinese Adults in Different Ethnic Groups Across Varied Altitudes | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 0:48


    Commentary by Dr.  Jian'an Wang.

    chinese groups adults commentary wang ethnic blood pressure varied brief introduction jian sleep patterns altitudes jacc
    Brief Introduction - Stepwise Assessment of Computational Coronary Physiology and Plaque Vulnerability: Impact on Coronary Revascularization Decision Making | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 1:14


    Commentary by Dr.  Jian'an Wang.

    vulnerability commentary decision making wang physiology plaque computational brief introduction coronary jian jacc revascularization stepwise

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