JACC Speciality Journals

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In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including o…

American College of Cardiology


    • Apr 14, 2026 LATEST EPISODE
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    Latest episodes from JACC Speciality Journals

    The Future of Cardio-Oncology: Progress and Priorities | ACC.26 | JACC: CardioOncology

    Play Episode Listen Later Apr 14, 2026 5:05


    At ACC.26, Dr. Tharshini Ramalingam speaks with JACC: CardioOncology Editor-in-Chief Dr. Bonnie Ky about the rapid evolution of cardio-oncology, the field's most urgent priorities, and the need for stronger evidence, risk prediction, cardioprotective strategies, and global implementation. Dr. Ky also shares practical advice for early-career investigators on mentorship, resilience, and what makes a manuscript impactful, rigorous, and truly additive to the field.

    progress priorities ky cardio oncology jacc
    Cardiogenic Shock From ICI Myocarditis With Predominant RV Failure | ACC.26 | JACC: CardioOncology

    Play Episode Listen Later Apr 14, 2026 6:16


    In this ACC.26 interview, Dr. Tharshini Ramalingam speaks with Dr. Eric Yang of UCLA about a rare and sobering case presented at ACC.26 of immune checkpoint inhibitor myocarditis with predominant right ventricular failure and cardiogenic shock. Their discussion highlights the diagnostic complexity of atypical myocarditis, the importance of recognizing unusual presentations, and the need for better screening, imaging, and phenotyping strategies in cardio-oncology care and research.

    failure ucla shock acc myocarditis predominant cardiogenic jacc
    Risk Scores for Transcatheter Tricuspid Interventions | JACC: Cardiovascular Interventions

    Play Episode Listen Later Apr 14, 2026 6:39


    Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Dr. Charles Davidson, discuss a recently published original research paper studying the transcatheter tricuspid valve intervention risk scores.

    md interventions cardiovascular social media editor jacc transcatheter risk scores tricuspid charles davidson
    Frequency and Outcomes of Acute Hemodynamic Instability Following TTVR | JACC: Cardiovascular Interventions

    Play Episode Listen Later Apr 14, 2026 5:29


    Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Dr. Volter Rudolph, discuss a recently published original research paper examining the frequency and outcomes of acute hemodynamic instability following tricuspid interventions.

    md outcomes frequency interventions acute cardiovascular instability hemodynamics social media editor jacc
    His-Pacing versus Biventricular Pacing for Cardiac Resynchronization Therapy: Long-term follow-up from the His-alternative I Trial | JACC: Clinical Electrophysiology

    Play Episode Listen Later Apr 14, 2026 2:56


    In this episode of JACC: Clinical Electrophysiology, Deputy Editor Dr. Kenneth Ellenbogen discusses His-Pacing versus Biventricular Pacing for Cardiac Resynchronization Therapy: Long-term follow-up from the His-alternative I Trial.

    therapy trial long term cardiac pacing jacc clinical electrophysiology
    Return-to-Play for Athletes with Desmosomal Arrhythmogenic Cardiomyopathy: A Single Center Experience | JACC: Clinical Electrophysiology

    Play Episode Listen Later Apr 14, 2026 5:46


    Deputy Editor Kenneth Ellenbogen hosts a focused discussion on the study "Return‑to‑Play for Athletes with Desmosomal Arrhythmogenic Cardiomyopathy: A Single Center Experience." In this episode, Dr. Ellenbogen examines how desmosomal arrhythmogenic cardiomyopathy impacts athletic participation and highlights real‑world insights from a single‑center cohort. He walks listeners through the clinical considerations, risk assessment strategies, and decision‑making frameworks that guide safe return‑to‑play recommendations for competitive athletes. This conversation offers valuable perspective for clinicians navigating the balance between athletic performance and long‑term cardiovascular safety.

    single athletes return to play ellenbogen cardiomyopathy jacc clinical electrophysiology
    Functional Conduction Block During Extra-Stimulus Mapping Masks Deceleration Zones and Reveals Additional VT Substrate | JACC: Clinical Electrophysiology

    Play Episode Listen Later Apr 14, 2026 4:59


    Deputy Editor Francis Marchlinski hosts a deep‑dive discussion on the study "Functional Conduction Block During Extra‑Stimulus Mapping Masks Deceleration Zones and Reveals Additional VT Substrate." In this episode, Dr. Marchlinski explores how extra‑stimulus pacing can alter the visualization of critical conduction deceleration zones and uncover previously hidden components of the ventricular tachycardia substrate. He breaks down the clinical implications of these dynamic changes and what they mean for improving VT mapping and ablation strategies.

    masks mapping functional stimulus zones vt substrate conduction deceleration jacc clinical electrophysiology
    LONG-TERM OUTCOMES AND SAFETY OF HIS-PURKINJE CONDUCTION SYSTEM PACING: A MULTICENTER OBSERVATIONAL STUDY IN CHINA (The ChiCSP Study)

    Play Episode Listen Later Apr 14, 2026 4:14


    Dr. Kenneth Ellebogen, Deputy Editor of JACC: Clinical Electrophysiology, discusses the long-term outcomes and safety of His-Purkinje conduction system pacing: a multicenter observational study in China.

    china system study safety pacing deputy editor conduction long term outcomes observational studies purkinje jacc clinical electrophysiology
    His Pacing vs Biventricular Pacing for Cardiac Resynchronization Therapy | JACC: Clinical Electrophysiology

    Play Episode Listen Later Apr 13, 2026 2:56


    In this episode, Dr. Kenneth Ellenbogen, Deputy Editor of JACC: Clinical Electrophysiology, discusses new long-term findings from the His-Alternative I trial, the first European randomized study comparing His-bundle pacing with conventional biventricular pacing for cardiac resynchronization therapy (CRT). He highlights five-year outcomes demonstrating that when His-bundle pacing is achieved with low implant thresholds, its long-term performance—including lead stability, generator replacements, and clinical response—closely mirrors that of biventricular CRT. Dr. Ellenbogen explores the implications of these results for contemporary conduction system pacing practice, the importance of strict implant criteria, and how these data help refine patient selection and procedural strategy in CRT.

    european therapy crt cardiac pacing deputy editor ellenbogen jacc clinical electrophysiology
    April 2026 Issue Summary | JACC: Asia

    Play Episode Listen Later Apr 9, 2026 7:42


    Audio Summary of the April 2026 Issue of JACC: Asia, by Dr. Jian'an Wang.

    wang jian jacc audio summary
    Profiles of Comprehensive Morphological Phenotypes and Outcomes in Functional Mitral Regurgitation | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:43


    Commentary by Dr. Jian'an Wang.

    commentary outcomes functional wang comprehensive profiles jian phenotypes regurgitation mitral jacc morphological
    The Effect of High-Density Lipoprotein on the Rheumatic Mitral Valve Calcification and Surgical Prognosis | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:49


    Commentary by Dr. Jian'an Wang.

    commentary wang valve surgical density prognosis jian lipoprotein mitral rheumatic calcification jacc
    Biological Age Acceleration and All-Cause Mortality in Moderate to Severe Aortic Valve Stenosis: A Prospective Cohort Study | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:48


    Commentary by Dr. Jian'an Wang.

    study commentary wang severe biological mortality valve acceleration moderate prospective cohorts jian aortic stenosis jacc
    Early Safety and Feasibility Study of a Novel Transcatheter Aortic Valve With Polymeric Leaflets | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 3:15


    Commentary by Dr. Shinichi Shirai.

    safety commentary valve aortic feasibility study jacc transcatheter leaflets
    Early Safety and Feasibility Study of a Novel Transcatheter Aortic Valve With Polymeric Leaflets | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:34


    Commentary by Dr. Jian'an Wang.

    safety commentary wang valve jian aortic feasibility study jacc transcatheter leaflets
    Effect of Device Size on Outcomes Following Left Atrial Appendage Closure in Borderline-Sized Anatomy | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:36


    Commentary by Dr. Jian'an Wang.

    left anatomy commentary outcomes wang closure device sized borderline atrial jian jacc
    Prognostic Value of Left Ventricular Kinetic Energy for Predicting Major Adverse Events in Hypertrophic Cardiomyopathy | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 2:56


    Commentary by Dr. Shujuan Yang.

    left commentary predicting adverse events ventricular hypertrophic cardiomyopathy kinetic energy jacc prognostic value
    Prognostic Value of Left Ventricular Kinetic Energy for Predicting Major Adverse Events in Hypertrophic Cardiomyopathy | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:35


    Commentary by Dr. Jian'an Wang.

    left commentary predicting wang adverse events jian ventricular hypertrophic cardiomyopathy kinetic energy jacc prognostic value
    Cardiometabolic Risk Among Internal Medicine Specialists in Indonesia (CARMEINA): A Nationwide Study | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:34


    Commentary by Dr. Jian'an Wang.

    risk study indonesia commentary wang nationwide internal medicine specialists jian jacc
    Left Atrial Strain Outperforms Ventricular Strains in Cardiovascular Outcome Association Across Echocardiography and Magnetic Resonance | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:35


    Commentary by Dr. Jian'an Wang.

    left commentary outcome wang cardiovascular strains atrial jian ventricular echocardiography jacc magnetic resonance
    Temporal Trends in Age Profile and Safety of Balloon Pulmonary Angioplasty for CTEPH | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:34


    Commentary by Dr. Jian'an Wang.

    safety commentary profile wang balloon pulmonary jian jacc angioplasty cteph temporal trends
    Importance and Management of Non-High-Density Lipoprotein Cholesterol in Dyslipidemia Treatment | JACC: Asia

    Play Episode Listen Later Apr 7, 2026 0:42


    Commentary by Dr. Jian'an Wang.

    management treatments commentary wang cholesterol density jian lipoprotein dyslipidemia jacc
    Use of Electrocardiograms to Identify Coronary Artery Disease: Cross-Validation of an Artificial Intelligence Model | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:28


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Use of Electrocardiograms to Identify Coronary Artery Disease: Cross-Validation of an Artificial Intelligence Model.

    cross model artificial intelligence identify validation advances arteries podcast editor coronary artery disease jacc
    VExUS Point-of-Care Ultrasound Tool to Detect Changes in Volume Status: A Prospective Observational Study | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:12


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on VExUS Point-of-Care Ultrasound Tool to Detect Changes in Volume Status: A Prospective Observational Study.

    study tool status advances prospective detect ultrasounds podcast editor observational studies care ultrasound jacc
    Comparative Strategies to Overcome Diuretic Resistance in Heart Failure: A Network Meta-Analysis | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 3:07


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Comparative Strategies to Overcome Diuretic Resistance in Heart Failure: A Network Meta-Analysis.

    strategy overcome resistance advances comparative heart failure podcast editor jacc diuretic network meta analysis
    Prehabilitation in Patients Undergoing Cardiac Procedures: A Systematic Review and Meta-Analysis | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:36


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prehabilitation in Patients Undergoing Cardiac Procedures: A Systematic Review and Meta-Analysis.

    patients advances procedures systematic cardiac meta analysis undergoing podcast editor jacc prehabilitation
    Pregnancy in Women With Impaired Left Ventricular Function: Data From ROPAC | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:32


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Pregnancy in Women With Impaired Left Ventricular Function: Data From ROPAC.

    women data left pregnancy function advances impaired podcast editor ventricular jacc ropac
    Cardiac Rehabilitation Utilization Among Veterans: A Sex-Based Analysis | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:50


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Cardiac Rehabilitation Utilization Among Veterans: A Sex-Based Analysis.

    veterans advances utilization podcast editor cardiac rehabilitation jacc
    Frailty Status Predicts Adverse Outcomes in Ambulatory Heart Failure With Preserved Ejection Fraction | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:50


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Frailty Status Predicts Adverse Outcomes in Ambulatory Heart Failure With Preserved Ejection Fraction.

    status advances predicts preserved heart failure ejection frailty fraction ambulatory podcast editor jacc adverse outcomes
    Intracoronary Vasoactive Therapy for No-Reflow During Primary PCI: A Network Meta-Analysis of Randomized Trials | JACC: Advances

    Play Episode Listen Later Mar 25, 2026 2:20


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Intracoronary Vasoactive Therapy for No-Reflow During Primary PCI: A Network Meta-Analysis of Randomized Trials.

    therapy trials primary advances randomized podcast editor jacc network meta analysis reflow
    Mechanical Debulking in Calcified Arteries: ROLLING STONE Study | JACC: Cardiovascular Interventions

    Play Episode Listen Later Mar 24, 2026 14:29


    Dr Aaysha Cader, Social media editor for JACC Interventions discusses the paper, Intravascular Lithotripsy or Mechanical Debulking in Complex Calcified Coronary Arteries: Multicenter, Prospective ROLLING STONE Study, with its first author, Dr Enrico Cerrato.

    social study rolling stones mechanical interventions cardiovascular arteries jacc
    TRANScatheter edge-to-edge rePAir for SAM related mitral REgurgitation in patieNTs with HCM. The TRANSPARENT registry | JACC: Cardiovascular Interventions

    Play Episode Listen Later Mar 20, 2026 14:20


    Dr Aaysha Cader, Social media editor for JACC Interventions discusses the paper, Transcatheter Edge-to-Edge Repair for SAM-Related Mitral Regurgitation in Patients With HCM: The TRANSPARENT Registry, with Professor Luca Testa.

    social patients repair transparent interventions cardiovascular registry regurgitation mitral jacc transcatheter
    Comparing High-Density Electroanatomical Mapping and MRI: a step forward in myocardial characterization in non-ischemic cardiomyopathy

    Play Episode Listen Later Mar 20, 2026 4:30


    Dr. Francis Marchlinski highlights new research comparing high‑density electroanatomical mapping with cardiac MRI in non‑ischemic cardiomyopathy. He explains how omnipolar mapping more accurately reflects MRI‑defined scar patterns—especially in deeper layers—and why this technology may offer a valuable alternative when MRI is limited or unavailable. A concise look at emerging tools reshaping arrhythmic risk assessment.

    comparing mapping mri density step forward characterization cardiomyopathy ischemic myocardial
    Predictors of Bleeding Complications After Extracorporeal Cardiopulmonary Resuscitation: Insights From the SAVE-J II Study | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 2:59


    Commentary by Dr. Qin LU.

    study commentary bleeding complications predictors jacc extracorporeal cardiopulmonary resuscitation
    Hemolysis After TAVR Using the Fifth-Generation Balloon-Expandable Valve: Comparison With the Third-Generation Valve | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 3:51


    Commentary by Dr. Matteo Sturla

    comparison commentary balloon valve third generation tavr fifth generation jacc expandable
    Diabetes and ALDH2 Gene Polymorphism on Post-Ablation Atrial Fibrillation Recurrence | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 2:59


    Commentary by Dr. Takeshi Aiba

    diabetes commentary atrial fibrillation recurrence ablation polymorphism jacc
    Brief Introduction - Predictors of Bleeding Complications After Extracorporeal Cardiopulmonary Resuscitation: Insights From the SAVE-J II Study | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:23


    Commentary by Dr.  Jian'an Wang.

    study commentary wang bleeding complications predictors brief introduction jian jacc extracorporeal cardiopulmonary resuscitation
    Brief Introduction - Suitability for Transcarotid Transcatheter Aortic Valve Replacement in the Japanese Population | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:00


    Commentary by Dr.  Jian'an Wang.

    japanese commentary population wang brief introduction jian suitability jacc transcatheter aortic valve replacement
    Brief Introduction - Hemolysis After TAVR Using the Fifth-Generation Balloon-Expandable Valve: Comparison With the Third-Generation Valve | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:13


    Commentary by Dr.  Jian'an Wang

    comparison commentary wang balloon valve brief introduction third generation jian tavr fifth generation jacc expandable
    Brief Introduction - Diabetes and ALDH2 Gene Polymorphism on Post-Ablation Atrial Fibrillation Recurrence | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:17


    Commentary by Dr.  Jian'an Wang

    diabetes commentary wang atrial fibrillation brief introduction recurrence ablation jian polymorphism jacc
    Brief Introduction - Phase 3, Open-Label Multicenter Study of Sotatercept in Japanese Participants With Pulmonary Arterial Hypertension | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:25


    Commentary by Dr.  Jian'an Wang

    japanese study commentary wang phase 3 brief introduction jian jacc pulmonary arterial hypertension open label
    Brief Introduction - Asia at the Epicentre of the Global Cardiometabolic Shift | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:16


    Commentary by Dr.  Jian'an Wang

    global shift commentary wang brief introduction jian epicentre jacc
    Brief Introduction - Medication Adherence and Antithrombotic Therapy Outcomes: Insights From a Post Hoc Analysis of the AFIRE Trial | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:20


    Commentary by Dr.  Jian'an Wang

    trial commentary outcomes medications wang brief introduction jian afire medication adherence jacc post hoc antithrombotic therapy
    Brief Introduction - Cholesterol-Inflammation Fusion Hypothesis in Atherosclerosis: An Evolving Paradigm in Pathogenesis and Therapy | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 1:31


    Commentary by Dr.  Jian'an Wang

    therapy evolving commentary fusion wang inflammation paradigm cholesterol hypothesis brief introduction atherosclerosis pathogenesis jian jacc
    March 2026 Issue Summary | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 11:39


    Audio Summary of the March 2026 Issue of JACC: Asia, by Dr. Jian'an Wang.

    wang jian jacc audio summary
    Phase 3, Open-Label Multicenter Study of Sotatercept in Japanese Participants With Pulmonary Arterial Hypertension (copy) | JACC: Asia

    Play Episode Listen Later Mar 3, 2026 3:41


    Commentary by Dr. Yunshan Cao

    japanese study commentary copy phase 3 jacc pulmonary arterial hypertension open label

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