JACC Speciality Journals

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In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including o…

American College of Cardiology


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    Latest episodes from JACC Speciality Journals

    Identifying Palliative Care Competencies for Cardiology Fellowship Training: A National Delphi Consensus Study | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 8:56


    Candice K. Silversides, MD, FACC, Editor-in-Chief of JACC: Advances, interviews authors Sarah Godfrey MD, MPH, FACC and Caroline L. Doherty DNP, AGACNP-BC, FACC about their paper, "Identifying Palliative Care Competencies for Cardiology Fellowship Training: A National Delphi Consensus Study" published in the February 2026 issue of the Journal.

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    Prognostic Value of CMR-Derived Left Ventricular Filling Pressure in Broad Referral Populations | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:43


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prognostic Value of CMR-Derived Left Ventricular Filling Pressure in Broad Referral Populations.

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    Atrial Fibrillation/Flutter in Transthyretin Cardiac Amyloidosis: Prevalence, Incidence, Clinical Predictors, and Effect of Tafamidis | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 3:03


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Atrial Fibrillation/Flutter in Transthyretin Cardiac Amyloidosis: Prevalence, Incidence, Clinical Predictors, and Effect of Tafamidis.

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    A 4-Decade Population-Based Registry of Thoracic Aortic Dissection Causing Sudden Death in the Young | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 3:13


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on A 4-Decade Population-Based Registry of Thoracic Aortic Dissection Causing Sudden Death in the Young.

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    Long-Term Cardiovascular Health Trajectories Associated With Cardiovascular Disease and Mortality in Older Adults | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:33


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Cardiovascular Health Trajectories Associated With Cardiovascular Disease and Mortality in Older Adults.

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    Risk Score Development to Predict Postpartum Cardiovascular Disease Incorporating Pregnancy and Nonpregnancy Factors: A Canada-Wide Study | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:49


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Risk Score Development to Predict Postpartum Cardiovascular Disease Incorporating Pregnancy and Nonpregnancy Factors: A Canada-Wide Study.

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    Increasing Awareness and Reducing Occupational Hazards in the Cardiac Catheterization and Electrophysiology Laboratories: Working to Eliminate Lead and Complications of Radiation in Cardiovascular Team Study | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:45


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Increasing Awareness and Reducing Occupational Hazards in the Cardiac Catheterization and Electrophysiology Laboratories: Working to Eliminate Lead and Complications of Radiation in Cardiovascular Team Study.

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    Multisite, External Validation of an AI-Enabled ECG Algorithm for Detection of Low Ejection Fraction | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:19


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Multisite, External Validation of an AI-Enabled ECG Algorithm for Detection of Low Ejection Fraction.

    algorithms external validation advances detection enabled ejection fraction podcast editor multisite jacc
    Device-Removal, Reinfection, and Mortality After Staphylococcus aureus Bacteremia in Patients With Cardiac Implantable Electronic Devices | JACC: Advances

    Play Episode Listen Later Feb 25, 2026 2:57


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Device-Removal, Reinfection, and Mortality After Staphylococcus aureus Bacteremia in Patients With Cardiac Implantable Electronic Devices.

    patients advances removal mortality cardiac podcast editor implantable electronic devices reinfection jacc staphylococcus aureus
    The Transmural Activation Interval in Dilated Cardiomyopathy: A New Mapping Tool for Intramural VT Substrates | JACC: Clinical Electrophysiology

    Play Episode Listen Later Feb 18, 2026 4:19


    Commentary by JACC: Clinical Electrophysiology Deputy Editor Francis Marchlinski, MD.

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    Polygenic risk for cardiometabolic and cardiovascular disease in a multi-ethnic cohort of breast cancer survivors | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 3:07


    Polygenic risk scores showed associations with several cardiometabolic outcomes in breast cancer survivors but did not improve prediction beyond traditional clinical factors. Their performance varied across ancestry groups and was weakened in patients exposed to cardiotoxic therapies, highlighting limits of current genetic risk tools.

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    Atrial Fibrillation Following Autologous Stem Cell Transplantation in Multiple Myeloma: Incidence, Predictors, and Prognostic Impact | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 3:28


    This study of 801 multiple myeloma patients found that atrial fibrillation occurred in 5.5% within 90 days after autologous stem cell transplantation—nearly double previously reported rates—indicating disease‑specific risks. AF strongly predicted mortality from non‑relapse causes and may serve as a marker of physiological vulnerability, emphasizing the value of expanded pre‑transplant cardiac assessment and monitoring.

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    CRISPR/Cas9 screens implicate RARA and SPNS1 in doxorubicin cardiotoxicity | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 3:15


    Researchers used genome‑wide CRISPR/Cas9 loss‑of‑function screens in cardiomyocytes to identify RARA and SPNS1 as key modulators of doxorubicin cardiotoxicity, highlighting pathways that influence both injury susceptibility and intracellular drug handling. Activation of RARA reduced toxicity without impairing anticancer effects, while SPNS1 loss caused harmful drug accumulation, offering new mechanistic insights and potential therapeutic targets.

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    Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 3:21


    This study analyzes over 2,600 transthyretin V142I variant carriers in the Million Veteran Program and finds significantly elevated risks of heart failure, cardiomyopathy, arrhythmias, neuropathy, and musculoskeletal complications compared with matched controls. Despite these risks, amyloidosis was rarely diagnosed clinically, underscoring major gaps in recognition and the need for earlier identification and multidisciplinary intervention.

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    February 2026 Full Issue Summary | JACC: CardioOncology

    Play Episode Listen Later Feb 17, 2026 14:33


    JACC: CardioOncology Volume 8 Issue 1 Full Issue Summary with Introduction by Dr. Bonnie Ky, Editor-in-Chief

    jacc
    Genotype-Guided vs. Conventional P2Y12 Inhibitors in ACS | JACC: CV Interventions | JACC: Cardiovascular Interventions

    Play Episode Listen Later Feb 13, 2026 6:47


    Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Mattio Galli, MD, PhD, discuss a recently published original research paper analyzing the role of genotype-guided escalation or de-escalation of antiplatelet therapy in acute coronary syndrome (ACS).

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    Bleeding in infarct related cardiogenic shock: DanGer Shock substudy | JACC: CV Interventions | JACC: Cardiovascular Interventions

    Play Episode Listen Later Feb 13, 2026 6:29


    Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Rikke Sørensen, MD, PhD, discuss a recently published original research paper from DanGer Shock substudy analyzing the bleeding events in patients with infarct related cardiogenic shock.

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    Brief Introduction - Sex Disparities in Ischemic Heart Disease in South Asia: The Role of Dietary Factors

    Play Episode Listen Later Feb 6, 2026 0:57


    Commentary by Dr.  Jian'an Wang.

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    Brief Introduction - Risk Prediction Models of Cardiotoxicity in Patients With Breast Cancer: Multicenter Prospective CHECK HEART-BC Study | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 0:44


    Commentary by Dr.  Jian'an Wang.

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    Brief Introduction - Interconnected Pathways and Therapeutic Implications for Cardiovascular Aging and Diseases | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 0:34


    Commentary by Dr.  Jian'an Wang.

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    Brief Introduction - Sleep Patterns and Blood Pressure Among Chinese Adults in Different Ethnic Groups Across Varied Altitudes | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 0:48


    Commentary by Dr.  Jian'an Wang.

    chinese groups adults commentary wang ethnic blood pressure varied brief introduction jian sleep patterns altitudes jacc
    Brief Introduction - Stepwise Assessment of Computational Coronary Physiology and Plaque Vulnerability: Impact on Coronary Revascularization Decision Making | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 1:14


    Commentary by Dr.  Jian'an Wang.

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    Brief Introduction - Effect of Proton Pump Inhibitors in Patients Undergoing Percutaneous Coronary Intervention With Aspirin-Free Strategy | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 1:18


    Commentary by Dr.  Jian'an Wang.

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    Brief Introduction - Associations Between Right Ventricular Remodeling, Exercise and Circulating Metabolites in Volume and Pressure Overload States | JACC: Asia

    Play Episode Listen Later Feb 6, 2026 0:44


    Commentary by Dr.  Jian'an Wang.

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    Integrated Use of Late Gadolinium Enhancement and Left Ventricular Global Longitudinal Strain in Hypertrophic Cardiomyopathy | JACC: Asia

    Play Episode Listen Later Feb 3, 2026 4:11


    Commentary by Dr.  Thomas Zegkos.

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    Sleep Patterns and Blood Pressure Among Chinese Adults in Different Ethnic Groups Across Varied Altitudes | JACC: Asia

    Play Episode Listen Later Feb 3, 2026 3:53


    Commentary by Dr.  Chhabi Satpathy.

    chinese groups adults commentary ethnic blood pressure varied sleep patterns altitudes jacc
    New-Onset Conductance Disturbances After TTVR | JACC: CV Interventions | JACC: Cardiovascular Interventions

    Play Episode Listen Later Jan 30, 2026 6:16


    Mirza Umair Khalid, MD, social media editor of JACC: Cardiovascular Interventions, and Dr. Rebecca Hahn, MD discuss a recently published study examining new onset conduction disturbances after TTVR.

    md interventions cardiovascular disturbances onset jacc
    Association Between Air Pollution and Monday Peak Mortality From Acute Myocardial Infarction | JACC: Advances

    Play Episode Listen Later Jan 28, 2026 2:33


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Association Between Air Pollution and Monday Peak Mortality From Acute Myocardial Infarction.

    peak advances mortality acute air pollution podcast editor myocardial infarction jacc
    Long-Term Outcomes: Beta-Blocker Use and Permanent Pacing in Patients With Heart Failure Preserved Ejection Fraction | JACC: Advances

    Play Episode Listen Later Jan 28, 2026 2:14


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Outcomes: Beta-Blocker Use and Permanent Pacing in Patients With Heart Failure Preserved Ejection Fraction.

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    Clinical Decision-Making of Artificial Intelligence vs Medical Professionals in Patients With Syncope | JACC: Advances

    Play Episode Listen Later Jan 28, 2026 3:04


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Clinical Decision-Making of Artificial Intelligence vs Medical Professionals in Patients With Syncope.

    patients artificial intelligence advances medical professionals podcast editor syncope clinical decision making jacc
    Additive Benefit of Guideline-Directed Medical Therapies at Discharge in Reducing 30-Day Readmissions in Heart Failure | JACC: Advances

    Play Episode Listen Later Jan 28, 2026 2:36


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Additive Benefit of Guideline-Directed Medical Therapies at Discharge in Reducing 30-Day Readmissions in Heart Failure.

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    Association of Pulmonary Artery Compliance and Adverse Cardiac Events | JACC: Advances

    Play Episode Listen Later Jan 28, 2026 2:43


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Association of Pulmonary Artery Compliance and Adverse Cardiac Events.

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    The Association Between Office, Video, and Telemanagement Encounters and GDMT Optimization in Advanced HFrEF | JACC: Advances

    Play Episode Listen Later Jan 28, 2026 2:45


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on The Association Between Office, Video, and Telemanagement Encounters and GDMT Optimization in Advanced HFrEF.

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    Vascular Health and Early Atherosclerosis in Childhood Cancer Survivors: Reassuring Findings From Comprehensive Noninvasive Assessment | JACC: Advances

    Play Episode Listen Later Jan 28, 2026 3:08


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Vascular Health and Early Atherosclerosis in Childhood Cancer Survivors: Reassuring Findings From Comprehensive Noninvasive Assessment.

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    Associations of Electromechanical Activation Time With Cardiac Structure and Function and Clinical Outcomes | JACC: Advances

    Play Episode Listen Later Jan 28, 2026 2:53


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Associations of Electromechanical Activation Time With Cardiac Structure and Function and Clinical Outcomes.

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    Cerebrovascular Ischemic Lesions After Pulsed Field Ablation for Atrial Fibrillation Using Variable-Loop Ablation Catheter | JACC: Clinical Electrophysiology

    Play Episode Listen Later Jan 27, 2026 15:24


    Dr. Emile Daoud, Deputy Editor of JACC Clinical Electrophysiology discusses Cerebrovascular Ischemic Lesions After Pulsed Field Ablation for Atrial Fibrillation Using Variable-Loop Ablation Catheter.

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    Transcatheter Tricuspid Valve Replacement in Patients with Cardiac Implantable Electronic Device Endocardial Leads: The TRIPLACE Registry | JACC: Clinical Electrophysiology

    Play Episode Listen Later Jan 27, 2026 11:12


    Commentary by JACC: Clinical Electrophysiology Executive Editor Emile Daoud, MD.

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    Brief Introduction - Transcatheter Electrosurgery in the Asia-Pacific: Implementation and Innovations | JACC: Asia

    Play Episode Listen Later Jan 16, 2026 0:57


    Commentary by Dr.  Jian'an Wang.

    innovation commentary wang implementation asia pacific brief introduction jian jacc transcatheter
    January 2026 Issue Summary | JACC: Asia

    Play Episode Listen Later Jan 16, 2026 12:06


    Audio Summary of the January 2026 Issue of JACC: Asia, by Dr. Jian'an Wang.

    wang jian jacc audio summary
    UNICORN for Valve-in-Valve Transcatheter Aortic Valve Replacement: UNICORN Hong Kong Registry | JACC: Asia

    Play Episode Listen Later Jan 16, 2026 1:04


    Commentary by Dr.  Jian'an Wang.

    hong kong unicorns commentary wang registry jian jacc transcatheter aortic valve replacement
    Brief Introduction - The Effect of Volume-Flow Discordance on Survival in Severe Aortic Stenosis | JACC: Asia

    Play Episode Listen Later Jan 16, 2026 0:47


    Commentary by Dr. Jian'an Wang.

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    Brief Introduction - Initial Real-World Experience of Tricuspid Transcatheter Edge-to-Edge Repair in Asia | JACC: Asia

    Play Episode Listen Later Jan 16, 2026 2:11


    Commentary by Dr.  Jian'an Wang

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    Brief Introduction - Prognostic Impact of Supranormal LVEF Following Mitral Valve TEER in Patients With Secondary Atrial MR | JACC: Asia

    Play Episode Listen Later Jan 16, 2026 1:51


    Commentary by Dr.  Jian'an Wang.

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    Brief Introduction - Antithrombotic Therapy After Percutaneous Left Atrial Appendage Closure: Results From the TERMINATOR Registry | JACC: Asia

    Play Episode Listen Later Jan 16, 2026 0:54


    Commentary by Dr. Jian'an Wang.

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    Brief Introduction - Accelerated Biological Aging, Genetic Predisposition, and Incident Valvular Heart Disease | JACC: Asia

    Play Episode Listen Later Jan 16, 2026 1:27


    Commentary by Dr. Jian'an Wang.

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    Antithrombotic Therapy After Percutaneous Left Atrial Appendage Closure: Results From the TERMINATOR Registry | JACC: Asia

    Play Episode Listen Later Jan 6, 2026 4:27


    Commentary by Dr. Sandeep Goyal.

    left commentary terminator closure registry atrial percutaneous jacc antithrombotic therapy

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