JACC Speciality Journals

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In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including o…

American College of Cardiology


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    Latest episodes from JACC Speciality Journals

    Integrated Hemodynamic Measures of Cardiac Function and Association With Clinical Outcomes | JACC: Advances

    Play Episode Listen Later Jun 24, 2026 2:44


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Integrated Hemodynamic Measures of Cardiac Function and Association With Clinical Outcomes.

    function advances measures integrated cardiac clinical outcomes podcast editor hemodynamics jacc
    SGLT2 Inhibitors in Cardio-Oncology: A Systematic Review and Meta-Analysis | JACC: Advances

    Play Episode Listen Later Jun 24, 2026 2:36


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on SGLT2 Inhibitors in Cardio-Oncology: A Systematic Review and Meta-Analysis.

    advances cardio oncology systematic meta analysis inhibitors sglt2 podcast editor jacc
    Sex Differences in Heart Transplantation Outcomes: A 5-Year Review of the 2018 U.S. Allocation Policy | JACC: Advances

    Play Episode Listen Later Jun 24, 2026 2:33


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sex Differences in Heart Transplantation Outcomes: A 5-Year Review of the 2018 U.S. Allocation Policy.

    policy outcomes advances allocation sex differences podcast editor year review jacc heart transplantation
    Audiovisual Distraction During Mitral Transcatheter Edge-to-Edge Repair: A Sedation-Sparing Randomized Trial | JACC: Advances

    Play Episode Listen Later Jun 24, 2026 2:44


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Audiovisual Distraction During Mitral Transcatheter Edge-to-Edge Repair: A Sedation-Sparing Randomized Trial.

    distractions repair advances audiovisual sedation sparing podcast editor randomized trial mitral jacc transcatheter
    Artificial Intelligence-Enhanced Electrocardiography and Health Records to Predict Cardiac Arrest | JACC: Advances

    Play Episode Listen Later Jun 23, 2026 2:34


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Artificial Intelligence-Enhanced Electrocardiography and Health Records to Predict Cardiac Arrest.

    artificial intelligence advances predict enhanced cardiac arrest podcast editor health records jacc
    Trends in the Co-Occurrence of Alcohol Use and Cardiovascular Disease Among U.S. Adults, 1999 to 2023 | JACC: Advances

    Play Episode Listen Later Jun 23, 2026 2:54


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Trends in the Co-Occurrence of Alcohol Use and Cardiovascular Disease Among U.S. Adults, 1999 to 2023.

    adults advances cardiovascular diseases occurrence alcohol use podcast editor jacc
    Associations of Central Adiposity With Subclinical Coronary Calcification and Disease Progression: Meta-Analysis of 68,629 Participants | JACC: Advances

    Play Episode Listen Later Jun 23, 2026 3:09


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Associations of Central Adiposity With Subclinical Coronary Calcification and Disease Progression: Meta-Analysis of 68,629 Participants.

    advances associations meta analysis coronary podcast editor subclinical disease progression calcification jacc adiposity
    Brief Introduction - Procedural Pattern, Clinical Outcomes, and Cost Analysis of Transcatheter Aortic Valve Replacement in Korea | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:30


    Commentary by Dr. Jian'an Wang.

    korea commentary pattern wang procedural brief introduction jian clinical outcomes cost analysis jacc transcatheter aortic valve replacement
    Brief Introduction - Single Versus Double Perclose Devices for TF-TAVR Access Closure: A Noninferiority Randomized Controlled Trial | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:11


    Commentary by Dr. Jian'an Wang.

    single commentary devices wang closure brief introduction randomized controlled trials jian tavr jacc
    Brief Introduction - SGLT2 Inhibition as a Novel Therapeutic Strategy in Rheumatic Heart Disease | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:01


    Commentary by Dr. Jian'an Wang.

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    Brief Introduction - Updated Wilkins Score Predicting Success of Balloon Mitral Valvuloplasty in Rheumatic Mitral Stenosis | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:04


    Commentary by Dr. Jian'an Wang.

    success score commentary predicting wang balloon wilkins brief introduction jian stenosis mitral rheumatic jacc
    Single Versus Double Perclose Devices for TF-TAVR Access Closure: A Noninferiority Randomized Controlled Trial | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 3:37


    Commentary by Dr. Jinho Lee.

    single commentary devices closure randomized controlled trials tavr jacc
    Updated Wilkins Score Predicting Success of Balloon Mitral Valvuloplasty in Rheumatic Mitral Stenosis | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 5:20


    Commentary by Dr. Kevin Kam.

    success score commentary predicting balloon wilkins stenosis mitral rheumatic jacc
    Transcatheter Aortic Valve Replacement in Functionally Dependent Patients: Analysis Using a Government-Adjudicated Long-Term Care Certification | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 2:46


    Commentary by Dr. Mark Tuttle.

    government patients commentary certification dependent long term care functionally jacc transcatheter aortic valve replacement
    Brief Introduction - Transcatheter Aortic Valve Replacement in Functionally Dependent Patients: Analysis Using a Government-Adjudicated Long-Term Care Certification | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:13


    Commentary by Dr. Jian'an Wang.

    government patients commentary wang certification dependent long term care brief introduction functionally jian jacc transcatheter aortic valve replacement
    Novel Allogeneic Mitochondria and Associated Organelle Complex Treatment Prevents Myocardial Ischemia-Reperfusion Injury Through Anti-Apoptotic Effects | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 3:10


    Commentary by Dr. Chrishan Ramachandra.

    treatments effects injury complex commentary prevents mitochondria ischemia allogeneic myocardial jacc reperfusion organelle apoptotic
    Brief Introduction - Novel Allogeneic Mitochondria and Associated Organelle Complex Treatment Prevents Myocardial Ischemia-Reperfusion Injury Through Anti-Apoptotic Effects | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:19


    Commentary by Dr. Jian'an Wang.

    treatments effects injury complex commentary wang prevents mitochondria brief introduction jian ischemia allogeneic myocardial jacc reperfusion organelle apoptotic
    Brief Introduction - Exercise and Exercise Stress Testing in Brugada Syndrome: Diagnostic, Prognostic, and Safety Implications | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 0:55


    Commentary by Dr. Jian'an Wang.

    safety exercise commentary implications wang diagnostic brief introduction jian stress testing prognostic jacc brugada syndrome
    Brief Introduction - Association Between Cardiovascular-Kidney-Metabolic Syndrome and Myocardial Injury After Noncardiac Surgery: A Retrospective Cohort Study | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:08


    Commentary by Dr. Jian'an Wang.

    study injury surgery commentary retrospective wang kidney cardiovascular cohorts metabolic syndrome brief introduction jian myocardial jacc
    Brief Introduction - Design of IKISS-LM Randomized Controlled Trial: Impact of Kissing Balloon Inflation on Provisional Left-Main Bifurcation PCI | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:05


    Commentary by Dr. Jian'an Wang.

    design left inflation commentary wang kissing balloon brief introduction provisional randomized controlled trials jian bifurcation jacc
    Brief Introduction - Myocardial Infarction Without Standard Modifiable Risk Factors From 2025-2040: Forecast Analysis of Multinational, Population-Based Study | JACC: Asia

    Play Episode Listen Later Jun 23, 2026 1:17


    Commentary by Dr. Jian'an Wang.

    study commentary population forecast wang risk factors multinational brief introduction jian myocardial infarction modifiable jacc
    August 2026 Full Issue Summary | JACC: CardioOncology

    Play Episode Listen Later Jun 16, 2026 20:43


    Audio summary of JACC: CardioOncology's June issue.

    jacc
    A Bleeding Risk Score for Cancer-Associated Venous Thromboembolism in Patients Receiving Direct Oral Anticoagulants | JACC: CardioOncology

    Play Episode Listen Later Jun 16, 2026 3:21


    This podcast by Dr. Larissa Araújo de Lucena discusses the development of the ONCO‑DOAC BLEED score for predicting major bleeding in patients with cancer‑associated venous thromboembolism (VTE) receiving direct oral anticoagulants. The findings support a more personalized, risk‑based approach to anticoagulation in cardio‑oncology, integrating cancer type, comorbidities, and clinical factors while highlighting the need for broader validation.

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    Differential Transthyretin Stabilization in Patients With Wild-Type and Variant Transthyretin Amyloidosis | JACC: CardioOncology

    Play Episode Listen Later Jun 16, 2026 6:19


    This podcast by Dr. Ron Witteles reviews new data on transthyretin amyloid cardiomyopathy (ATTR‑CM), highlighting differences in transthyretin stabilization between acoramidis and tafamidis across wild-type and variant disease. The discussion underscores the clinical importance of TTR stabilization, emerging biomarkers such as serum transthyretin, and the expanding therapeutic landscape in cardiac amyloidosis.

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    Immune Profiling Identifies Inflammatory Signatures in Immune Checkpoint Inhibitor– Related Myocarditis | JACC: CardioOncology

    Play Episode Listen Later Jun 16, 2026 3:00


    This podcast by Dr. Dan Zlotoff reviews new research on immune checkpoint inhibitor–associated myocarditis, a rare but serious complication of cancer immunotherapy, focusing on emerging inflammatory biomarkers such as interleukin‑6 and immune cell signatures. The study highlights potential pathways for risk stratification and targeted therapies, while underscoring the need for larger trials to develop reliable diagnostic and treatment strategies in cardio‑oncology.

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    Upper Extremity Deep Vein Thrombosis in Cancer Patients: Clinical Course by Cancer Site | JACC: CardioOncology

    Play Episode Listen Later Jun 16, 2026 3:31


    This podcast by Dr. António Araújo highlights new insights from a large international registry study showing that cancer‑associated upper extremity deep vein thrombosis (UEDVT) carries increased risks of recurrent venous thromboembolism and bleeding. The findings emphasize tumor‑specific risk patterns and support more personalized anticoagulation strategies in cardio‑oncology.

    ant clinical cancer patients upper extremity deep vein thrombosis jacc
    Association Between Clonal Hematopoiesis and Cardiometabolic Disease: A Systematic Review and Meta-Analysis | JACC: CardioOncology

    Play Episode Listen Later Jun 16, 2026 3:06


    This podcast by Dr. Marie Pigeyre explores emerging evidence on clonal hematopoiesis, highlighting its role as a systemic driver of inflammation and its association with increased risk of cardiovascular disease, stroke, and type 2 diabetes. The discussion emphasizes the growing importance of clonal hematopoiesis in cardiometabolic risk, precision prevention, and aging biology, while noting that routine clinical screening is not yet recommended.

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    Comparison of Flow Ratio Derived From IVUS With CAG in Complex Lesions: Correlation With FFR | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:31


    Commentary by Dr. Jian'an Wang.

    comparison complex commentary wang ratio correlation derived lesions jian jacc ivus
    Sex Differences in Antiarrhythmic Effects of Empagliflozin: The EMPA-ICD Trial Subanalysis | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:30


    Commentary by Dr. Jian'an Wang.

    trial effects commentary wang sex differences jian jacc empagliflozin
    Association Between Cardiac Acceleration Capacity and Susceptibility to Vasovagal Syncope: Autonomic Dysregulation in Vasovagal Syncope | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:24


    Commentary by Dr. Jian'an Wang.

    commentary capacity wang acceleration cardiac dysregulation autonomic susceptibility jian syncope jacc
    Cardio-Kidney-Metabolic Phenotypes and Adverse Clinical Outcomes in Patients With Atrial Fibrillation | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:22


    Commentary by Dr. Jian'an Wang.

    patients commentary wang cardio kidney metabolic adverse atrial fibrillation jian clinical outcomes phenotypes jacc
    Postoperative New-Onset Heart Block in Noncardiac Surgery: Model Development, Validation, and Long-Term Prognostic Analysis | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:25


    Commentary by Dr. Jian'an Wang.

    development model long term surgery commentary validation wang onset jian postoperative prognostic jacc heart block
    The Associations Between Heart Rate, Deformational Echocardiographic Parameters, and Outcomes in Patients With Atrial Fibrillation | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:31


    Commentary by Dr. Jian'an Wang.

    patients commentary outcomes wang associations parameters heart rate atrial fibrillation jian jacc
    Sex Differences in Antiarrhythmic Effects of Empagliflozin: The EMPA-ICD Trial Subanalysis | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:30


    Commentary by Dr. Jian'an Wang.

    trial effects commentary wang sex differences jian jacc empagliflozin
    Development of a Noninvasive Prediction Score for Post-Capillary Pulmonary Hypertension in a Multi-Ethnic Asian Population | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:34


    Commentary by Dr. Jian'an Wang.

    predictions development asian score commentary population wang ethnic jian pulmonary hypertension noninvasive capillary jacc
    Ambrisentan for Early-Stage Low-Risk Pulmonary Arterial Hypertension: Design of the Randomized, Double-Blind, Placebo-Controlled ALEPH Trial | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:30


    Commentary by Dr. Jian'an Wang.

    design trial blind commentary wang placebos early stage aleph randomized low risk jian jacc pulmonary arterial hypertension placebo controlled
    Persistent Atrial Fibrillation With Conduction System Pacing or Pulmonary Vein Isolation: A Prospective Cohort Study | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:29


    Commentary by Dr. Jian'an Wang.

    system study isolation commentary wang persistent pacing prospective cohorts pulmonary vein atrial fibrillation jian conduction jacc
    Conceptual Reconsideration of the Classification of Pulmonary Hypertension: From 5 Groups to 2 Groups | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:30


    Commentary by Dr. Jian'an Wang.

    groups commentary wang classification conceptual jian pulmonary hypertension reconsideration jacc
    Prognostic Value of Murray's Law–Based Quantitative Flow Ratio in Multi-Arterial Coronary Artery Bypass Grafting | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:33


    Commentary by Dr. Jian'an Wang.

    commentary wang ratio bypass quantitative arteries arterial coronary grafting jian jacc prognostic value
    Comparison of Clinical Outcomes Between Incomplete and Complete Revascularization in NSTEMI Patients With Multivessel Disease | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:37


    Commentary by Dr. Jian'an Wang.

    patients disease comparison commentary wang incomplete jian clinical outcomes jacc nstemi revascularization
    Comparison of Flow Ratio Derived From IVUS With CAG in Complex Lesions: Correlation With FFR | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:31


    Commentary by Dr. Jian'an Wang.

    comparison complex commentary wang ratio correlation derived lesions jian jacc ivus
    CRP Cutoff Value in East Asians With Coronary Heart Disease: A Systematic Review and Meta-Analysis | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:35


    Commentary by Dr. Jian'an Wang.

    commentary wang asians cutoff systematic east asian meta analysis jian coronary heart disease jacc
    Validation and Recalibration of PCE, China-PAR and PREVENT Models for Estimating ASCVD Risk in China | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:45


    Commentary by Dr. Jian'an Wang.

    china risk prevent commentary models validation wang estimating recalibration jian ascvd jacc
    Accelerometer-Measured Sedentary Behavior, Future Disease, and Cardiovascular-Kidney-Metabolic Health | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:53


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Accelerometer-Measured Sedentary Behavior, Future Disease, and Cardiovascular-Kidney-Metabolic Health.

    disease behavior advances kidney cardiovascular measured metabolic health sedentary podcast editor jacc accelerometer
    Differential Association Between Surrounding Greenness and Mortality in Individuals With Coronary Heart Disease | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:45


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Differential Association Between Surrounding Greenness and Mortality in Individuals With Coronary Heart Disease.

    individuals surrounding advances mortality differential podcast editor coronary heart disease jacc
    Sex Differences in Cardiac Involvement in Adults With Myotonic Dystrophy Type 1: A Multicenter Study | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:43


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sex Differences in Cardiac Involvement in Adults With Myotonic Dystrophy Type 1: A Multicenter Study.

    study adults advances involvement cardiac type1 sex differences podcast editor dystrophy jacc myotonic

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