JACC Speciality Journals

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In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including o…

American College of Cardiology


    • Jun 2, 2026 LATEST EPISODE
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    Latest episodes from JACC Speciality Journals

    Comparison of Flow Ratio Derived From IVUS With CAG in Complex Lesions: Correlation With FFR | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:31


    Sex Differences in Antiarrhythmic Effects of Empagliflozin: The EMPA-ICD Trial Subanalysis | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:30


    Association Between Cardiac Acceleration Capacity and Susceptibility to Vasovagal Syncope: Autonomic Dysregulation in Vasovagal Syncope | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:24


    Cardio-Kidney-Metabolic Phenotypes and Adverse Clinical Outcomes in Patients With Atrial Fibrillation | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:22


    Postoperative New-Onset Heart Block in Noncardiac Surgery: Model Development, Validation, and Long-Term Prognostic Analysis | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:25


    The Associations Between Heart Rate, Deformational Echocardiographic Parameters, and Outcomes in Patients With Atrial Fibrillation | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:31


    Sex Differences in Antiarrhythmic Effects of Empagliflozin: The EMPA-ICD Trial Subanalysis | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:30


    Development of a Noninvasive Prediction Score for Post-Capillary Pulmonary Hypertension in a Multi-Ethnic Asian Population | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:34


    Ambrisentan for Early-Stage Low-Risk Pulmonary Arterial Hypertension: Design of the Randomized, Double-Blind, Placebo-Controlled ALEPH Trial | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:30


    Persistent Atrial Fibrillation With Conduction System Pacing or Pulmonary Vein Isolation: A Prospective Cohort Study | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:29


    Conceptual Reconsideration of the Classification of Pulmonary Hypertension: From 5 Groups to 2 Groups | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:30


    Prognostic Value of Murray's Law–Based Quantitative Flow Ratio in Multi-Arterial Coronary Artery Bypass Grafting | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:33


    Comparison of Clinical Outcomes Between Incomplete and Complete Revascularization in NSTEMI Patients With Multivessel Disease | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:37


    Comparison of Flow Ratio Derived From IVUS With CAG in Complex Lesions: Correlation With FFR | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:31


    CRP Cutoff Value in East Asians With Coronary Heart Disease: A Systematic Review and Meta-Analysis | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:35


    Validation and Recalibration of PCE, China-PAR and PREVENT Models for Estimating ASCVD Risk in China | JACC Asia

    Play Episode Listen Later Jun 2, 2026 0:45


    Accelerometer-Measured Sedentary Behavior, Future Disease, and Cardiovascular-Kidney-Metabolic Health | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:53


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Accelerometer-Measured Sedentary Behavior, Future Disease, and Cardiovascular-Kidney-Metabolic Health.

    Differential Association Between Surrounding Greenness and Mortality in Individuals With Coronary Heart Disease | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:45


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Differential Association Between Surrounding Greenness and Mortality in Individuals With Coronary Heart Disease.

    Sex Differences in Cardiac Involvement in Adults With Myotonic Dystrophy Type 1: A Multicenter Study | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:43


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sex Differences in Cardiac Involvement in Adults With Myotonic Dystrophy Type 1: A Multicenter Study.

    Characteristics, Management, and Outcomes of Diabetes Subtypes in Patients With Cardiogenic Shock: A Nationwide Analysis | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:26


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Characteristics, Management, and Outcomes of Diabetes Subtypes in Patients With Cardiogenic Shock: A Nationwide Analysis.

    Comparison of Microcirculation in Chronic Heart Failure, Cardiogenic Shock, LVAD, and Heart Transplantation | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:48


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Comparison of Microcirculation in Chronic Heart Failure, Cardiogenic Shock, LVAD, and Heart Transplantation.

    Early Diagnosis of ATTR-CM by Age- and Carpal Tunnel Biopsy-Guided Screening | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:48


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Early Diagnosis of ATTR-CM by Age- and Carpal Tunnel Biopsy-Guided Screening.

    Generalizability of Landmark Temporary MCS Device Trials: Insights From the CSWG Registry | JACC: Advances

    Play Episode Listen Later May 27, 2026 2:39


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Generalizability of Landmark Temporary MCS Device Trials: Insights From the CSWG Registry.

    Long-Term Outcomes of Targeted Volume Overload Management in Patients With Severe Aortic Stenosis | JACC: Advances

    Play Episode Listen Later May 27, 2026 3:08


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Outcomes of Targeted Volume Overload Management in Patients With Severe Aortic Stenosis.

    Should Interventionalists Get an MBA? Wayne Batchelor, MD, MHS, MBA Responds | JACC: Cardiovascular Interventions

    Play Episode Listen Later May 26, 2026 20:39


    Dr. Mohamad Alkhouli speaks with Dr. Wayne Batchelor about what leadership truly means for mid‑career interventional cardiologists and whether pursuing an MBA adds value. Dr. Batchelor highlights trust, communication, and business fluency as essential skills for physician leaders navigating increasingly complex healthcare systems.

    Should Interventionalists Get an MBA? Kirk Garratt, MD, MSc Responds | JACC: Cardiovascular Interventions

    Play Episode Listen Later May 21, 2026 26:33


    Dr. Mohamad Alkhouli and Dr. Kirk Garratt discuss leadership in interventional cardiology, highlighting the importance of empathy, communication, and advocacy alongside clinical expertise. Dr. Garratt encourages physicians to intentionally develop leadership skills—through training or experience—as healthcare systems become more complex.

    Should Interventionalists Get an MBA? J. Dawn Abbott, MD Responds | JACC: Cardiovascular Interventions

    Play Episode Listen Later May 21, 2026 28:01


    In this conversation, Dr. Mohamad Alkhouli speaks with Dr. Abbott about her leadership journey in interventional cardiology, focusing on how curiosity, mentorship, and skill development organically lead to meaningful leadership roles. Dr. Abbott shares practical insights on motivating teams, navigating complex healthcare systems, and whether formal business training such as an MBA is necessary for physician leaders.

    Should Interventionalists Get an MBA? Deepak Bhatt, MD, MPH, MBA Responds | JACC: Cardiovascular Interventions

    Play Episode Listen Later May 21, 2026 24:36


    Dr. Mohamad Alkhouli and Dr. Deepak Bhatt discuss leadership development in interventional cardiology and the value of pursuing an executive MBA mid‑career. Dr. Bhatt shares insights on how business training—from finance to leadership and strategy—can help physicians navigate increasingly complex healthcare systems and become more effective stewards of patient care and resources.

    Postoperative New-Onset Heart Block in Noncardiac Surgery: Model Development, Validation, and Long-Term Prognostic Analysis | JACC: Asia

    Play Episode Listen Later May 5, 2026 4:00


    Sex-Based Differences in Clinical Outcomes With Edoxaban Therapy: A Prespecified Analysis of the EPIC-CAD Trial | JACC: Asia

    Play Episode Listen Later May 5, 2026 2:29


    Commentary by Dr. Satoshi Shizuta.

    The Associations Between Heart Rate, Deformational Echocardiographic Parameters and Outcomes in Patients With Atrial Fibrillation | JACC: Asia

    Play Episode Listen Later May 5, 2026 3:49


    Cardio-Kidney-Metabolic Phenotypes and Adverse Clinical Outcomes in Patients With Atrial Fibrillation | JACC: Asia

    Play Episode Listen Later May 5, 2026 3:03


    Long PR Interval Leads to Atrial Remodeling, Fibrosis and Inducible Atrial Fibrillation in a Swine Model | JACC: Clinical Electrophysiology

    Play Episode Listen Later Apr 23, 2026 3:06


    Deputy Editor Kenneth Ellenbogen presents an in‑depth discussion of the study "Long PR Interval Leads to Atrial Remodeling, Fibrosis and Inducible Atrial Fibrillation in a Swine Model." In this episode, Dr. Ellenbogen walks listeners through how prolonged atrioventricular conduction can drive structural and electrical remodeling in the atria, leading to fibrosis and increased susceptibility to atrial fibrillation. He highlights the significance of these findings for understanding AF pathophysiology and considers how this preclinical model may inform future prevention and treatment strategies.

    A Pulsed Field Ablation-Based Endocardial Strategy for Ventricular Tachycardia in Arrhythmogenic Right Ventricular Cardiomyopathy | JACC: Clinical Electrophysiology

    Play Episode Listen Later Apr 23, 2026 3:38


    In this podcast, Francis Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a novel pulsed field ablation–based endocardial strategy for ventricular tachycardia in patients with arrhythmogenic right ventricular cardiomyopathy. The paper presents an early consecutive experience demonstrating the feasibility, acute effectiveness, and safety of PFA for VT without the need for epicardial access. Dr. Marchlinski highlights the clinical implications of this approach and how tissue-selective, nonthermal energy may expand treatment options for this challenging patient population.

    Incidence of Worsening Aortic Regurgitation After Mapping and Ablation in the Aortic Cusps | JACC: Clinical Electrophysiology

    Play Episode Listen Later Apr 23, 2026 4:12


    In this podcast, Francis Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a large multicenter study evaluating the incidence and clinical significance of aortic regurgitation following mapping and ablation of ventricular arrhythmias in the aortic cusps and commissures. Drawing on contemporary data from four high‑volume centers, the paper provides important reassurance regarding the safety of aortic cusp ablation, demonstrating that clinically significant aortic regurgitation is rare and infrequently progressive. Dr. Marchlinski highlights the key findings, procedural considerations, and implications for everyday practice in ventricular arrhythmia ablation.

    Associations of Socioeconomic Status With Cardiorenal Metabolic Multimorbidity: Evidence From the UK Biobank Cohort | JACC: Advances

    Play Episode Listen Later Apr 22, 2026 3:06


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Associations of Socioeconomic Status With Cardiorenal Metabolic Multimorbidity: Evidence From the UK Biobank Cohort.

    Dietary Sodium Intake and Risk of Incident Heart Failure in the Southern Community Cohort Study | JACC: Advances

    Play Episode Listen Later Apr 22, 2026 2:49


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Dietary Sodium Intake and Risk of Incident Heart Failure in the Southern Community Cohort Study.

    Coronary Sinus Reduction for REDUCER-I Patients With Refractory Angina and Angiographically Nonobstructive Coronary Artery Disease | JACC: Advances

    Play Episode Listen Later Apr 22, 2026 3:15


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Coronary Sinus Reduction for REDUCER-I Patients With Refractory Angina and Angiographically Nonobstructive Coronary Artery Disease.

    Remote Management of Patients With Heart Failure in Medically Underserved Areas | JACC: Advances

    Play Episode Listen Later Apr 22, 2026 2:42


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Remote Management of Patients With Heart Failure in Medically Underserved Areas.

    Development of a Predictive Tool in Patients With High Pretest Probability for Transthyretin Amyloid Cardiomyopathy | JACC: Advances

    Play Episode Listen Later Apr 22, 2026 3:24


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Development of a Predictive Tool in Patients With High Pretest Probability for Transthyretin Amyloid Cardiomyopathy.

    Valvular Heart Diseases in Swedish Males and Females: A National Cohort Study | JACC: Advances

    Play Episode Listen Later Apr 22, 2026 2:22


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Valvular Heart Diseases in Swedish Males and Females: A National Cohort Study.

    Cardiovascular-Kidney-Metabolic Syndrome and Life Expectancy in U.S. Adults | JACC: Advances

    Play Episode Listen Later Apr 22, 2026 2:48


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Cardiovascular-Kidney-Metabolic Syndrome and Life Expectancy in U.S. Adults.

    10-Year Excess Mortality After First-Time Non–ST-Segment Elevation Myocardial Infarction: The Western Denmark Heart Registry | JACC: Advances | JACC: Advances

    Play Episode Listen Later Apr 22, 2026 2:29


    Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on 10-Year Excess Mortality After First-Time Non–ST-Segment Elevation Myocardial Infarction: The Western Denmark Heart Registry.

    Cardiac Biomarker Complete Response in AL Amyloidosis | JACC: CardioOncology

    Play Episode Listen Later Apr 21, 2026 3:32


    Dr. Michel G. Khouri reviews a landmark study examining patients with AL amyloidosis who achieved a complete cardiac biomarker response, highlighting profound improvements in cardiac structure, function, and long-term survival that rival the general population. The discussion underscores the transformative impact of early diagnosis and modern plasma cell–directed therapies, while reminding clinicians that ongoing multidisciplinary cardiac care remains essential even after sustained cardiac remission.

    Cardiovascular Adverse Events Associated with Bispecific T-cell Engager Therapy | JACC: CardioOncology

    Play Episode Listen Later Apr 21, 2026 3:23


    Dr. Qun Shao discusses two multicenter studies evaluating cardiovascular adverse events associated with bispecific T‑cell engager therapies. Drawing on data from over 700 patients, the episode highlights the incidence, predictors, and clinical impact of cardiovascular complications, emphasizing the importance of baseline risk assessment, targeted monitoring, and multidisciplinary management as use of these therapies continues to expand.

    Myocardial Expression of PD-L1 as a Marker of Poor Prognosis in Immune Checkpoint Inhibitor–Associated Myocarditis | JACC: CardioOncology

    Play Episode Listen Later Apr 21, 2026 2:06


    Research fellow, Adrian Chen, discusses a multicenter study evaluating myocardial PD‑L1 expression as a prognostic biomarker in immune checkpoint inhibitor–associated myocarditis. The conversation highlights how elevated myocardial PD‑L1 identifies patients at markedly higher risk for early adverse cardiac events and explores its potential role in improving risk stratification and guiding earlier, more aggressive therapy in this high‑risk population.

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