JACC Speciality Journals

Commentary by Dr. Qin LU.

Commentary by Dr. Matteo Sturla

Commentary by Dr. Takeshi Aiba

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Jian'an Wang

Commentary by Dr.  Jian'an Wang

Commentary by Dr.  Jian'an Wang

Commentary by Dr.  Jian'an Wang

Commentary by Dr.  Jian'an Wang

Commentary by Dr.  Jian'an Wang

Audio Summary of the March 2026 Issue of JACC: Asia, by Dr. Jian'an Wang.

Commentary by Dr. Yunshan Cao

Candice K. Silversides, MD, FACC, Editor-in-Chief of JACC: Advances, interviews authors Sarah Godfrey MD, MPH, FACC and Caroline L. Doherty DNP, AGACNP-BC, FACC about their paper, "Identifying Palliative Care Competencies for Cardiology Fellowship Training: A National Delphi Consensus Study" published in the February 2026 issue of the Journal.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prognostic Value of CMR-Derived Left Ventricular Filling Pressure in Broad Referral Populations.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Atrial Fibrillation/Flutter in Transthyretin Cardiac Amyloidosis: Prevalence, Incidence, Clinical Predictors, and Effect of Tafamidis.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on A 4-Decade Population-Based Registry of Thoracic Aortic Dissection Causing Sudden Death in the Young.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Cardiovascular Health Trajectories Associated With Cardiovascular Disease and Mortality in Older Adults.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Risk Score Development to Predict Postpartum Cardiovascular Disease Incorporating Pregnancy and Nonpregnancy Factors: A Canada-Wide Study.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Increasing Awareness and Reducing Occupational Hazards in the Cardiac Catheterization and Electrophysiology Laboratories: Working to Eliminate Lead and Complications of Radiation in Cardiovascular Team Study.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Multisite, External Validation of an AI-Enabled ECG Algorithm for Detection of Low Ejection Fraction.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Device-Removal, Reinfection, and Mortality After Staphylococcus aureus Bacteremia in Patients With Cardiac Implantable Electronic Devices.

Commentary by JACC: Clinical Electrophysiology Deputy Editor Francis Marchlinski, MD.

Polygenic risk scores showed associations with several cardiometabolic outcomes in breast cancer survivors but did not improve prediction beyond traditional clinical factors. Their performance varied across ancestry groups and was weakened in patients exposed to cardiotoxic therapies, highlighting limits of current genetic risk tools.

This study of 801 multiple myeloma patients found that atrial fibrillation occurred in 5.5% within 90 days after autologous stem cell transplantation—nearly double previously reported rates—indicating disease‑specific risks. AF strongly predicted mortality from non‑relapse causes and may serve as a marker of physiological vulnerability, emphasizing the value of expanded pre‑transplant cardiac assessment and monitoring.

Researchers used genome‑wide CRISPR/Cas9 loss‑of‑function screens in cardiomyocytes to identify RARA and SPNS1 as key modulators of doxorubicin cardiotoxicity, highlighting pathways that influence both injury susceptibility and intracellular drug handling. Activation of RARA reduced toxicity without impairing anticancer effects, while SPNS1 loss caused harmful drug accumulation, offering new mechanistic insights and potential therapeutic targets.

This study analyzes over 2,600 transthyretin V142I variant carriers in the Million Veteran Program and finds significantly elevated risks of heart failure, cardiomyopathy, arrhythmias, neuropathy, and musculoskeletal complications compared with matched controls. Despite these risks, amyloidosis was rarely diagnosed clinically, underscoring major gaps in recognition and the need for earlier identification and multidisciplinary intervention.

JACC: CardioOncology Volume 8 Issue 1 Full Issue Summary with Introduction by Dr. Bonnie Ky, Editor-in-Chief

Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Mattio Galli, MD, PhD, discuss a recently published original research paper analyzing the role of genotype-guided escalation or de-escalation of antiplatelet therapy in acute coronary syndrome (ACS).

Mirza Umair Khalid, MD, Social Media Editor for JACC: Cardiovascular Interventions, and Rikke Sørensen, MD, PhD, discuss a recently published original research paper from DanGer Shock substudy analyzing the bleeding events in patients with infarct related cardiogenic shock.

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Jian'an Wang.

Commentary by Dr.  Thomas Zegkos.

Commentary by Dr.  Chhabi Satpathy.

Mirza Umair Khalid, MD, social media editor of JACC: Cardiovascular Interventions, and Dr. Rebecca Hahn, MD discuss a recently published study examining new onset conduction disturbances after TTVR.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Association Between Air Pollution and Monday Peak Mortality From Acute Myocardial Infarction.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Outcomes: Beta-Blocker Use and Permanent Pacing in Patients With Heart Failure Preserved Ejection Fraction.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Clinical Decision-Making of Artificial Intelligence vs Medical Professionals in Patients With Syncope.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Additive Benefit of Guideline-Directed Medical Therapies at Discharge in Reducing 30-Day Readmissions in Heart Failure.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Association of Pulmonary Artery Compliance and Adverse Cardiac Events.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on The Association Between Office, Video, and Telemanagement Encounters and GDMT Optimization in Advanced HFrEF.