Podcasts about Regurgitation

Welcome back for another monthly Akashic Forecast episode!Today we're diving into APRIL, another powerful month of death and rebirth, of purging and restoration, of highs and lows. We'll be stripping down to the bare minimum and making decisions about Who We Want To Be and discovering Who We Are. It's not a month to push or force, it's a month to become more mindful, more aware, and to make spiritual practices a daily practice! You're going to need it for what's ahead.APRIL Akashic Themes: 1) Arms of Justice 2) Regurgitation 3) Slowing Down 4) Eating, Eating, Eating 5) Life Vest.“Sometimes it feels as if you are living from a third person, and yet of course you are nestled deep inside of yourself.Part of what is taking place here is that you are coming to understand that you are so much more than a human body. In fact, you are a soul, and these two are different indeed.Yes, you have your human experience, but also you have the experience in which your soul signed up to experience through this incarnation – the dips, the valleys, the highs and lows, all that which you go through life, each and every step why it serves a purpose for you, if you choose to see it that way.Yet you have been allowing yourself to get caught up in the ramblings and shakings of that which is taking place on the planet, if not in the exterior, then certainly within your interior.But don't you understand that it is shaking you loose from that which no longer serves?”Enjoy and let me know how it resonates :))Read the transcript HERE: https://open.substack.com/pub/souldrivencollective/p/april-akashic-forecast-shaking-youCONNECT ONLINEInstagram https://www.instagram.com/ahnahendrixYouTube https://www.youtube.com/channel/UC5fsN8oqu8Ib8IcvpYZA4jQ APRIL Events & Offerings* APRIL Events:* 4/9 Akashic Guidance Circle 7pm EST* 4/24 Akashic Restoration GROUP Session: 7pm EST* LINK: https://ahnahendrix.as.me/?appointmentType=76240776* Access the Akashic Records: Self Study Course: https://ahnahendrix.com/access-the-akashic-records-self-study-course/ Get full access to The Soul Driven Collective at souldrivencollective.substack.com/subscribe

Guest: Susheel Kodali, MD Susheel Kodali, MD, director of the Structural Heart and Valve Center at NewYork-Presbyterian and Columbia, shares more about an innovative transcatheter therapy for tricuspid regurgitation (TR), which is providing a new treatment option that vastly improves quality of life. Results from the TRISCEND II trial demonstrated the safety and efficacy of a tricuspid valve replacement system, which was fast-tracked for FDA approval due to its clear benefit for the vulnerable TR patient population. © 2025 NewYork-Presbyterian

Transcatheter Aortic Valve Repair for Aortic Regurgitation with the Cusper Device

This special issue of JACC is dedicated to the essential role of cardiovascular surgery in advancing modern cardiology.

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826241300881

The Tri.Fr Randomized Clinical Trial evaluated the efficacy of Transcatheter Edge-to-Edge Repair (T-TEER) + Optimized Medical Therapy (OMT) versus OMT alone in 300 patients with severe, symptomatic tricuspid regurgitation (TR) across 24 centers in France and Belgium. At 1-year follow-up, 74.1% of patients in the T-TEER group improved, compared to 40.6% in the OMT-alone group (P < .001). T-TEER significantly reduced TR severity, improved NYHA class, patient global assessment (PGA), and Kansas City Cardiomyopathy Questionnaire (KCCQ) scores, and had a high procedural success rate (97.3%) with a low 30-day major adverse event rate (0.7%). The findings support T-TEER as an effective intervention for symptomatic severe TR, warranting long-term follow-up to assess mortality and hospitalization impact.

“Prahlada Maharaja replied: Because of their uncontrolled senses, persons too addicted to materialistic life make progress toward hellish conditions and repeatedly chew that which has already been chewed. Their inclinations toward Krishna are never aroused, either by the instructions of others, by their own efforts, or by a combination of both.” (Shrimad Bhagavatam, 7.5.30)

The Rich Zeoli Show- Hour 1: 3:05pm- Speaking from the Roosevelt Room of the White House on Tuesday night, President Donald Trump held a press conference announcing OpenAI, Oracle, SoftBank, and several other companies will invest $500 billion to build the nation's artificial intelligence infrastructure. While some are vocally expressing fear that A.I. could lead to a societal downfall, Rich expresses optimism. He notes that its necessary for the U.S. to drive advancements in the critical technological field—as the alternative would be to allow geopolitical rival China to dominate the sphere which would have catastrophic implications for national security. 3:40pm- Brianna Lyman—Elections Correspondent for The Federalist—joins The Rich Zeoli Show to discuss her latest article, “Media's Regurgitation of Baseless Hegseth Allegations Prove They Learned Nothing Post-Election.” You can read the full article here: https://thefederalist.com/2025/01/22/medias-regurgitation-of-baseless-hegseth-allegations-prove-they-learned-nothing-post-election/

The Rich Zeoli Show- Full Episode (01/22/2025): 3:05pm- Speaking from the Roosevelt Room of the White House on Tuesday night, President Donald Trump held a press conference announcing OpenAI, Oracle, SoftBank, and several other companies will invest $500 billion to build the nation's artificial intelligence infrastructure. While some are vocally expressing fear that A.I. could lead to a societal downfall, Rich expresses optimism. He notes that its necessary for the U.S. to drive advancements in the critical technological field—as the alternative would be to allow geopolitical rival China to dominate the sphere which would have catastrophic implications for national security. 3:40pm- Brianna Lyman—Elections Correspondent for The Federalist—joins The Rich Zeoli Show to discuss her latest article, “Media's Regurgitation of Baseless Hegseth Allegations Prove They Learned Nothing Post-Election.” You can read the full article here: https://thefederalist.com/2025/01/22/medias-regurgitation-of-baseless-hegseth-allegations-prove-they-learned-nothing-post-election/ 4:05pm- Rich is still recovering from his foot surgery—and decides to take his medicine live on air…how exciting! 4:10pm- Philadelphia Mayor Cherelle Parker led a crowd in an Eagles chant following the team's big win against the Los Angeles Rams—but she somehow misspelled “Eagles.” 4:20pm- In a press conference, Canadian Prime Minister Justin Trudeau—who is the son of former Canadian Prime Minister Pierre Trudeau and definitely not former Cuban dictator Fidel Castro—warned President Donald Trump against imposing tariffs on Canada. 4:30pm- On Wednesday, President Donald Trump picked New Jersey State Senator Douglas J. Steinhardt to serve as acting U.S. Attorney for New Jersey. 4:40pm- In a series of Executive Orders signed on Monday night from the Oval Office, President Donald Trump mandated employees of the federal government work in-person, withdrew the nation from the Paris Climate Agreement, withdrew the nation from the World Health Organization (WHO) citing their willingness to cover-up China's COVID-19 transgressions, delayed enforcement of a national ban of TikTok, recognized two genders—male and female, pardoned 1,500 Americans arrested for their actions on January 6th, 2021, expanded domestic energy production, shut down the U.S. Southern border, and guaranteed free speech on social media. Trump also fulfilled a long-term campaign pledge to focus on meritocracy and pivot away from the prioritization of far-left policies like diversity, equity, and inclusion (D.E.I.) within the federal government. 4:45pm- Trump Delivers on His Promise to Dismantle DEI: Jason Riley, opinion columnist for The Wall Street Journal, writes: “It's no surprise that increasing the salience of race, and favoring some groups over others, can only harm the social cohesion necessary to sustain a multiethnic society. A Gallup poll released last week found that a plurality of Americans (39%) said that race relations had worsened under Mr. Biden, versus just 24% who said they had improved.” You can read t full article here: https://www.wsj.com/opinion/trump-delivers-on-his-promise-to-dismantle-dei-race-ethnicity-policy-f5847d0a 5:00pm- Gerald Posner—Award-Winning Investigative Journalist & Author of the book “Pharma: Greed, Lies, and the Poisoning of America”—joins The Rich Zeoli Show to discuss his latest article, “Hitler, Musk, and the Art of the Smear.” PLUS, Rich and Posner debate the Kennedy assassination. Will President Donald Trump release the JFK files, as he pledged to do on the campaign trail? You can read the full article here: https://www.justthefacts.media/p/hitler-musk-and-the-art-of-the-smear 5:20pm- Appearing on Fox News with Lawrence Jones, Trump Administration Border Czar Tom Homan revealed that since Donald Trump took office on Monday I.C.E. has arrested over 100 dangerous criminals who entered the country illegally. 5:25pm- While speaking to reporters outside o ...

TRISCEND II: Randomized Comparison of Transcatheter Valve Replacement vs. Optimal Medical Therapy for Severe Tricuspid Regurgitation

Acute medical management of valvulopathy.  Part I talks about the pathophysiology and management of regurgitant valves: AI, MR, and TR.  Great Core Ultrasound post on POCUS assessment of valvulopathy: https://coreultrasound.com/valves-2/Additional content and educational resources at ICUedu.org

Introduction (00:00 - 03:00) Dr. Valentin Fuster introduces the focus of the January 28, 2025, issue of JACC on transcatheter tricuspid valve interventions. He emphasizes the growing importance of addressing symptomatic tricuspid regurgitation, a major predictor of morbidity and mortality, and explores potential treatments that aim to improve quality of life and decrease hospitalizations. Transcatheter Tricuspid Valve Repair (03:00 - 20:30) Fuster discusses two key studies: the TRILUMINATE randomized trial and a large European registry. While the TRILUMINATE trial demonstrated significant quality of life improvements using the TriClip device, it did not show a reduction in mortality or heart failure hospitalizations, suggesting the need for longer follow-up in future studies. Meanwhile, the European registry highlights the effectiveness of the Pascal device, showing significant symptomatic improvements and tricuspid regurgitation reduction in high-risk patients. Transcatheter Tricuspid Valve Replacement (20:30 - 35:00) Fuster moves on to discuss the TRISCEND II pivotal trial on transcatheter tricuspid valve replacement. Like the previous repair methods, it primarily improves health status without significantly reducing mortality or hospitalizations, as shown in the trial's findings. He also mentions an excellent state-of-the-art review on this intervention featured in JACC. Imaging in Transcatheter Valve Interventions (35:00 - 45:00) This section highlights the importance of imaging in transcatheter valve interventions. Fuster presents a new project under the leadership of Dr. Kalyanam Shivkumar, aimed at enhancing cardiac anatomy and function resources, supporting advancements in cardiovascular treatments. Conclusion (45:00 - 55:00) Dr. Valentin Fuster wraps up the podcast by summarizing the key takeaways: while current transcatheter interventions show promise in improving symptoms and quality of life for patients with severe tricuspid regurgitation, long-term follow-up is crucial to fully understand their impact on survival and heart failure hospitalizations.

Introduction (00:00 - 03:00) Dr. Valentin Fuster introduces the focus of the January 28, 2025, issue of JACC on transcatheter tricuspid valve interventions. He emphasizes the growing importance of addressing symptomatic tricuspid regurgitation, a major predictor of morbidity and mortality, and explores potential treatments that aim to improve quality of life and decrease hospitalizations. Transcatheter Tricuspid Valve Repair (03:00 - 20:30) Fuster discusses two key studies: the TRILUMINATE randomized trial and a large European registry. While the TRILUMINATE trial demonstrated significant quality of life improvements using the TriClip device, it did not show a reduction in mortality or heart failure hospitalizations, suggesting the need for longer follow-up in future studies. Meanwhile, the European registry highlights the effectiveness of the Pascal device, showing significant symptomatic improvements and tricuspid regurgitation reduction in high-risk patients. Transcatheter Tricuspid Valve Replacement (20:30 - 35:00) Fuster moves on to discuss the TRISCEND II pivotal trial on transcatheter tricuspid valve replacement. Like the previous repair methods, it primarily improves health status without significantly reducing mortality or hospitalizations, as shown in the trial's findings. He also mentions an excellent state-of-the-art review on this intervention featured in JACC. Imaging in Transcatheter Valve Interventions (35:00 - 45:00) This section highlights the importance of imaging in transcatheter valve interventions. Fuster presents a new project under the leadership of Dr. Kalyanam Shivkumar, aimed at enhancing cardiac anatomy and function resources, supporting advancements in cardiovascular treatments. Conclusion (45:00 - 55:00) Dr. Valentin Fuster wraps up the podcast by summarizing the key takeaways: while current transcatheter interventions show promise in improving symptoms and quality of life for patients with severe tricuspid regurgitation, long-term follow-up is crucial to fully understand their impact on survival and heart failure hospitalizations.

Introduction (00:00 - 03:00) Dr. Valentin Fuster introduces the focus of the January 28, 2025, issue of JACC on transcatheter tricuspid valve interventions. He emphasizes the growing importance of addressing symptomatic tricuspid regurgitation, a major predictor of morbidity and mortality, and explores potential treatments that aim to improve quality of life and decrease hospitalizations. Transcatheter Tricuspid Valve Repair (03:00 - 20:30) Fuster discusses two key studies: the TRILUMINATE randomized trial and a large European registry. While the TRILUMINATE trial demonstrated significant quality of life improvements using the TriClip device, it did not show a reduction in mortality or heart failure hospitalizations, suggesting the need for longer follow-up in future studies. Meanwhile, the European registry highlights the effectiveness of the Pascal device, showing significant symptomatic improvements and tricuspid regurgitation reduction in high-risk patients. Transcatheter Tricuspid Valve Replacement (20:30 - 35:00) Fuster moves on to discuss the TRISCEND II pivotal trial on transcatheter tricuspid valve replacement. Like the previous repair methods, it primarily improves health status without significantly reducing mortality or hospitalizations, as shown in the trial's findings. He also mentions an excellent state-of-the-art review on this intervention featured in JACC. Imaging in Transcatheter Valve Interventions (35:00 - 45:00) This section highlights the importance of imaging in transcatheter valve interventions. Fuster presents a new project under the leadership of Dr. Kalyanam Shivkumar, aimed at enhancing cardiac anatomy and function resources, supporting advancements in cardiovascular treatments. Conclusion (45:00 - 55:00) Dr. Valentin Fuster wraps up the podcast by summarizing the key takeaways: while current transcatheter interventions show promise in improving symptoms and quality of life for patients with severe tricuspid regurgitation, long-term follow-up is crucial to fully understand their impact on survival and heart failure hospitalizations.

Introduction (00:00 - 03:00) Dr. Valentin Fuster introduces the focus of the January 28, 2025, issue of JACC on transcatheter tricuspid valve interventions. He emphasizes the growing importance of addressing symptomatic tricuspid regurgitation, a major predictor of morbidity and mortality, and explores potential treatments that aim to improve quality of life and decrease hospitalizations. Transcatheter Tricuspid Valve Repair (03:00 - 20:30) Fuster discusses two key studies: the TRILUMINATE randomized trial and a large European registry. While the TRILUMINATE trial demonstrated significant quality of life improvements using the TriClip device, it did not show a reduction in mortality or heart failure hospitalizations, suggesting the need for longer follow-up in future studies. Meanwhile, the European registry highlights the effectiveness of the Pascal device, showing significant symptomatic improvements and tricuspid regurgitation reduction in high-risk patients. Transcatheter Tricuspid Valve Replacement (20:30 - 35:00) Fuster moves on to discuss the TRISCEND II pivotal trial on transcatheter tricuspid valve replacement. Like the previous repair methods, it primarily improves health status without significantly reducing mortality or hospitalizations, as shown in the trial's findings. He also mentions an excellent state-of-the-art review on this intervention featured in JACC. Imaging in Transcatheter Valve Interventions (35:00 - 45:00) This section highlights the importance of imaging in transcatheter valve interventions. Fuster presents a new project under the leadership of Dr. Kalyanam Shivkumar, aimed at enhancing cardiac anatomy and function resources, supporting advancements in cardiovascular treatments. Conclusion (45:00 - 55:00) Dr. Valentin Fuster wraps up the podcast by summarizing the key takeaways: while current transcatheter interventions show promise in improving symptoms and quality of life for patients with severe tricuspid regurgitation, long-term follow-up is crucial to fully understand their impact on survival and heart failure hospitalizations.

On this episode of The Karen Kenney Show, I discuss the importance of "slow learning" - especially in a culture that's become so focused on “fast outcomes” and “quick results”. I share about my own experiences of needing enough time to truly understand and integrate new information, rather than just quickly consuming it. I make the case that true learning, comes from first-hand experience and the process of acquiring knowledge through implementation and not just passively ingesting other people's content. I also reflect on how some learning methods have changed over time - and I contrast this modern approach with traditional apprenticeship models. I believe that true knowledge requires effort and patience - the willingness to spend time with material, think deeply about it, and allow it to percolate. Which is one of the reasons why I'm not a fan of the “TLDR” culture that we seem to find ourselves in.This is an invitation to forgo the instant gratification and superficial understanding that so often dominates today. Ultimately, I encourage people to adopt a more "vertical" approach to learning and personal growth - going deeper rather than wider, and being willing to invest the time and attention required for true learning and understanding.KEY POINTS:•​ Embracing slow, deep learning•​ Resisting cultural obsession with speed•​ True knowledge requires patience + effort•​ Regurgitation does not equal understanding•​ Cultivating long-term learning relationships•​ Prioritizing Depth over Breadth• The Nest - Group Mentoring Program BIO:Karen Kenney is a certified Spiritual Mentor, Writer, Integrative Change Worker, Coach and Hypnotist. She's known for her dynamic storytelling, her sense of humor, her Boston accent, and her no-BS, down-to-earth approach to Spirituality and transformational work. KK is a wicked curious human being, a life-long learner, and has been an entrepreneur for over 20 years! She's also a yoga teacher of 24+ years, a Certified Gateless Writing Instructor, and an author, speaker, retreat leader, and the host of The Karen Kenney Show podcast.She coaches both the conscious + unconscious mind using practical Neuroscience, Subconscious Reprogramming, Integrative Hypnosis/Change Work, and Spiritual Mentorship. These tools help clients to regulate their nervous systems, remove blocks, rewrite stories, rewire beliefs, and reimagine what's possible in their lives and business!Karen encourages people to deepen their connection to Self, Source and Spirit in down-to-earth and actionable ways and wants them to have their own lived experience with spirituality and to not just “take her word for it”.She helps people to shift their minds from fear to Love - using compassion, storytelling and humor. Her work is effective, efficient, memorable, and fun!KK's been a student of A Course in Miracles for close to 30 years, has been vegan for over 20 years, and believes that a little kindness can make a big difference.KK WEBSITE: www.karenkenney.com

CLASP IID 2 Year: RCT and Registry: Two-Year Outcomes of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation

In this episode, Dr. Valentin Fuster delves into the latest research surrounding the use of the mitral clip for patients with severe functional mitral regurgitation, comparing the results of three major trials: the French MITRA-FR trial, the American COAPT trial, and the Reshape HF 2 trial. While the COAPT and Reshape HF 2 trials show positive outcomes, especially in reducing hospitalizations and improving heart failure symptoms, the French trial saw no benefit, prompting debate over the influence of left ventricular volume and disease severity on treatment success, with expert opinions calling for further studies and individualized meta-analyses.

In this episode, Dr. Valentin Fuster delves into the latest research surrounding the use of the mitral clip for patients with severe functional mitral regurgitation, comparing the results of three major trials: the French MITRA-FR trial, the American COAPT trial, and the Reshape HF 2 trial. While the COAPT and Reshape HF 2 trials show positive outcomes, especially in reducing hospitalizations and improving heart failure symptoms, the French trial saw no benefit, prompting debate over the influence of left ventricular volume and disease severity on treatment success, with expert opinions calling for further studies and individualized meta-analyses.

RESHAPE-HF2 – Percutaneous Repair of Moderate-to-Severe or Severe Functional Mitral Regurgitation in Patients with Symptomatic Heart Failure

In this podcast, Dr. Valentin Fuster discusses a groundbreaking study on using artificial intelligence (AI) in electrocardiograms (ECGs) to assess left ventricular diastolic function and predict outcomes in patients with significant mitral regurgitation. The study demonstrates that AI-driven ECGs can offer comparable prognostic value to traditional echocardiography, identifying high-risk patients and potentially revolutionizing cardiovascular diagnostics, though challenges around sensitivity, specificity, and patient selection remain.

Send us an inquiry through a text message here!Buy Tickets To Our LIVE Show Here: https://www.eventbrite.com/e/the-veterinary-roundtable-live-podcast-show-at-vmx-2025-tickets-948280842527?aff=oddtdtcreatorWelcome to another episode of The Veterinary Roundtable! In this episode, the ladies make a HUGE announcement that you won't want to miss, discuss what factors made them decide on a specific vet school, debate the pros and cons of outdoor cats vs indoor cats, and more!Do you have a question or inquiry for The Veterinary Roundtable? Send us a text from the link above, ask us on any social media platform, or email harrison@kingmediamarketing.com!Episodes of The Veterinary Roundtable are on all podcast services along with video form on YouTube!Instagram: https://tinyurl.com/2h27xnfuTikTok: https://tinyurl.com/m8f62ameYouTube: https://tinyurl.com/48njfywdTIMESTAMPSIntro 00:00Veterinary Themed Drinks For The 100th Episode 02:55Announcing The Veterinary Roundtable LIVE At VMX 2025 06:16Pits And Peaks 11:48Deciding What Vet School To Go To (@Lizzy) 21:56Outdoor Cats vs Indoor Cats (@Caitlin) 27:29Case Collections 34:27Advice For Dealing With Regurgitation In Pets 46:30Outro 54:30

Mirza Umair Khalid, MD, social media editor of JACC: Cardiovascular Interventions, and Thomas J. Stocker, MD, discuss a recently published original research paper reporting the long-term outcomes after mitral transcatheter edge-to-edge repair for secondary mitral regurgitation.

This episode I'm relieving my mind of some very colorful and obnoxious thoughts. You won't be encouraged, but YOU WILL LAUGH!!!

Kellie got her final veneers today! You can't see how white they are, but you can finally hear her talk lisp-free. Add this to the list of ailments! Kellie had a four-hour heart issue at an appearance in Fort Worth that had Allen pretty worried.  After Allen gives an update on his speeding ticket, is it Christmas already??? Everyone in their neighborhood is already putting up trees and lighting up their houses, but Allen apparently threw away all their outdoor decorations last year, which is news to Kellie. And if you're planning on getting a new puppy for Christmas, Kellie has the list of the top dog names of 2024.  Allen goes off on his Cowboys rant of the week, which leads Kellie to tell him about a new product coming next year — Crier-Ball Whiskey!  And the pool guy saved their dog Larry from drowning, which led to a shocking statement from Kellie.  Thank you to our podcast sponsors!  Spice up your fall look with Thrive Causemetics. Luxury beauty that gives back! Right now, you can get an exclusive 20% off your first order at thrivecausemetics.com/SANDWICH.  If you're ready for a great night's sleep, you're in luck! Helix is offering 25% off sitewide plus 2 FREE Dream Pillows with any mattress purchase. And if you grab one of their Luxe or Elite mattresses, you'll get a free bedding bundle — 2 dream pillows, a sheet set and mattress protector! Go to HelixSleep.com/Sandwich. Learn more about your ad choices. Visit megaphone.fm/adchoices

Interview with Barry A. Borlaug, MD, and Jwan A. Naser, MBBS, authors of Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation. Hosted by James E. Udelson, MD. Related Content: Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation

Interview with Barry A. Borlaug, MD, and Jwan A. Naser, MBBS, authors of Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation. Hosted by James E. Udelson, MD. Related Content: Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation

MATTERHORN – Transcatheter Versus Surgical Mitral Valve Repair in Patients With Heart Failure and Secondary Mitral Regurgitation

In this episode of the Saving Lives Podcast, Eddy Joe explores the TRISCEND II trial's groundbreaking findings on transcatheter tricuspid valve replacement (TTVR) for severe tricuspid regurgitation. Learn about the quality-of-life improvements, procedural risks, and future directions for this innovative therapy. The Vasopressor & Inotrope HandbookAmazon: https://amzn.to/3UvFFVf (affiliate link) Signed Copy: https://eddyjoemd.myshopify.com/products/the-vasopressor-inotrope-handbook Citation: https://www.nejm.org/doi/full/10.1056/NEJMoa2401918 --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

JACC Associate Editor Celina M. Yong, MD, FACC, and JACC: Case Reports Editor in Chief Gilbert H. L. Tang, MD, MSc, MBA, FACC, discuss this paper published in JACC and presented at TCT. TRILUMINATE Pivotal is the first randomized, controlled trial evaluating transcatheter edge-to-edge repair (T-TEER) for severe tricuspid regurgitation (TR). Adaptive design randomized 572 subjects in the primary or subsequent cohorts. Subjects were elderly with atrial fibrillation and prior HFH. Primary endpoint was met at 1 year with a larger win ratio for T-TEER driven by KCCQ improvement with no significant differences in mortality and tricuspid valve surgery or HFH.

Author Joerg Hausleiter, MD and Executive Associate Editor Aakriti Gupta, MD, FACC. discuss the TAVR UNLOAD trial, which focused on patients with moderate aortic stenosis (AS) and reduced ejection fraction (HFrEF). The trial found no significant difference in the primary endpoint (composite of mortality, stroke, and hospitalizations) between the TAVR and clinical surveillance groups. However, patients who underwent TAVR showed a significant improvement in quality of life at one year. The conversation highlighted the need for individualized treatment approaches, emphasizing patient selection, while also considering trial limitations, including slow enrollment and study size.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on mortality burden for patients with untreated aortic regurgitation.

Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.

Editor-in-Chief Eric Rubin and Deputy Editor Jane Leopold discuss research that was presented at the 2024 European Society of Cardiology annual meeting. Visit NEJM.org to read the latest research.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on a novel hemodynamic index characterizing mitral regurgitation undergoing transcatheter edge to edge repair

Abdullah Al-Abcha, MD, social media editor of JACC: Cardiovascular Interventions, and Firas Zahr, MD, discuss a recently published original research paper on a study that aimed to assess the impact of tricuspid regurgitation on outcomes of TAVR with balloon expandable valves.

Commentary by Dr. Candice Silversides

Mirza Umair Khalid, MD, social media editor of JACC: Cardiovascular Interventions, and Maria Isabel Körber, MD, discuss a recently published original research paper investigating clinical and echocardiographic outcomes in patients who underwent transcatheter TV annuloplasty for atrial and nonatrial functional tricuspid regurgitation.

Audio Commentary by Dr. Valentin Fuster, Emeritus Editor in Chief

CardioNerds cofounder, Amit Goyal joins Dr. Belal Suleiman, Dr. Nkiru Osude, and Dr. David Elliott from Duke University. They discuss a case of severe mitral paravalvular regurgitation complicated by hemolytic anemia. Expert commentary is provided by Dr. Andrew Wang. Audio editing by CardioNerds Academy Intern, student doctor Adriana Mares. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Case Media - Severe Mitral Paravalvular Regurgitation Complicated by Hemolytic Anemia - Duke University

When to Repair vs. Replacement for Tricuspid Regurgitation

Tune in for Think on your Feet XLIV, in which the play through of The Innsmouth Conspiracy, featuring Subject 5U-21, continues.  In Think on your Feet episodes, a live play series, I endeavour not to edit much at all. Sometimes I cut some shuffling sounds or abbreviate some of my longer pauses (a chap's got to think!), but otherwise, it's uncut, unaltered and meant to feel like you're with me at the table. There may be mistakes and misplays, but hopefully some successes too. Timestamps:  0.00 intro / preamble  2.35 scenario intro 5.12 setup / vehicle rules / locations / fishing vessel 9.23 act / agenda 10.30 opening hand 12.30 gameplay begins 1.08.50 gameplay ends, resolution, wrap up Three times (19.05, 34.11, 56.07) Peter takes a 4-action turn, but then the same turn or the next turn he spends an action to play Regurgitation, so it always evens out.   At 47.20 Peter forgets to move The Thing That Follows. Here's the deck: CLICK ME Amazing logo courtesy of this guy Join Drawn to the Flame on Patreon: www.patreon.com/drawntotheflame Buy Drawn to the Flame shirts, jumpers and mugs: www.designbyhumans.com/shop/drawntotheflame Email us on drawntotheflamepodcast@gmail.com | Twitter is here and Facebook is here. Thank you for listening and subscribing.

Commentary by Dr. Valentin Fuster

ESC TV Today brings you concise analysis from the world's leading experts, so you can stay on top of what's happening in your field quickly. This episode covers: Cardiology This Week: A concise summary of recent studies All you need to know about omega-3 fatty acids Lead induced tricuspid regurgitation MythBusters: Pomegranates are heart-healthy Host: Rick Grobbee Guests: Carlos Aguiar, Martin Andreas, Deepak Bhatt Want to watch that episode? Go to: https://esc365.escardio.org/event/1150 Disclaimer This programme is intended for health care professionals only and is to be used for educational purposes. The European Society of Cardiology (ESC) does not aim to promote medicinal products nor devices. Any views or opinions expressed are the presenters' own and do not reflect the views of the ESC. Declarations of interests Stephan Achenbach, Rick Grobbee and Nicolle Kraenkel have declared to have no potential conflicts of interest to report. Carlos Aguiar has declared to have potential conflicts of interest to report: personal fees for consultancy and/or speaker fees from Abbott, AbbVie, Alnylam, Amgen, AstraZeneca, Bayer, Boehringer-Ingelheim, Daiichi-Sankyo, Ferrer, Gilead, Lilly, Novartis, Pfizer, Sanofi, Servier, Tecnimede. Martin Andreas has declared to have potential conflicts of interest to report: proctor/speaker/consultant (Edwards, Abbott, Medtronic, Boston, Braun, Zoll) and institutional Research Grants (Edwards, Abbott, Medtronic, LSI). Deepak Bhatt has declared to have potential conflicts of interest to report: research funding from Amarin paid to Brigham and Women's Hospital and the Icahn School of Medicine at Mount Sinai for my role as Principal Investigator of REDUCE-IT. Davide Capodanno has declared to have potential conflicts of interest to report: Abbott Vascular, Novo Nordisk, Sanofi. Terumo, Medtronic. Emma Svennberg has declared to have potential conflicts of interest to report: institutional research grants from Abbott, Astra Zeneca, Bayer, Bristol-Myers, Squibb-Pfizer, Boehringer-Ingelheim, Johnson & Johnson, Merck Sharp & Dohme.

Energetic Health Radio with Dr. Henry Ealy – Fact is true no matter who you ask. Faith is true only to the person who believes it. In this episode of Energetic Health Radio, Dr. H has an adult conversation about distinguishing the difference between fact and faith and the role it plays in our journey towards re-enlightenment. A journey of purpose found in the service of others. A journey of kindness and truth...

Energetic Health Radio with Dr. Henry Ealy – Fact is true no matter who you ask. Faith is true only to the person who believes it. In this episode of Energetic Health Radio, Dr. H has an adult conversation about distinguishing the difference between fact and faith and the role it plays in our journey towards re-enlightenment. A journey of purpose found in the service of others. A journey of kindness and truth...

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·       Nascentmc.com for medical writing assistance for your company.Visit nascentmc.com/podcast for full show notes Cilta-cel for Myeloma: The FDA approved ciltacabtagene autoleucel (Carvykti; cilta-cel) for adults with relapsed or refractory multiple myeloma who have tried at least one prior therapy including a proteasome inhibitor and an immunomodulatory agent, and are refractory to lenalidomide. This CAR T-cell therapy, initially approved in 2022, was confirmed effective in the phase 3 CARTITUDE-4 study, showing significant reduction in disease progression or death risk by 59% compared to standard care. Enhertu for HER2-positive Solid Tumors: Fam-trastuzumab deruxtecan-nxki (Enhertu) received FDA approval for treating unresectable or metastatic HER2-positive solid tumors in adults who have had previous systemic treatment and lack satisfactory alternative options. This therapy, a conjugate of an anti-HER2 antibody and a cytotoxic drug, was first approved in 2019 and targets HER2-expressing cancer cells to potentially minimize damage to normal tissues. Fanapt for Bipolar: Iloperidone (Fanapt) has been approved for the acute treatment of manic or mixed episodes in adults with bipolar I disorder. Previously approved for schizophrenia, iloperidone targets neurotransmitters like dopamine and serotonin. It demonstrated efficacy in a pivotal trial, showing significant improvement on the Young Mania Rating Scale. Zevtera for Multiple Bacterial Infections: Ceftobiprole medocaril sodium (Zevtera) was approved for treating adults with Staphylococcus aureus bloodstream infections, right-sided infective endocarditis, and acute bacterial skin and skin structure infections. Also approved for pediatric community-acquired bacterial pneumonia, ceftobiprole is a broad-spectrum cephalosporin that combats various bacteria including MRSA. TriClip for Tricuspid Regurgitation: The FDA approved the TriClip™ transcatheter edge-to-edge repair system for treating tricuspid regurgitation. This minimally invasive option clips the tricuspid valve leaflets to improve blood flow and prevent the need for surgery. The TRILUMINATE Pivotal trial showed significant improvements in TR severity and quality of life with a good safety profile. Revumenib for Acute Leukemia: The FDA granted priority review to revumenib (SNDX-5613) for treating adult and pediatric patients with relapsed or refractory acute leukemia with KMT2A rearrangements. As a new therapeutic agent, revumenib inhibits the menin-MLL protein interaction crucial in leukemic transformation. Early trial results show promising remission rates, with a PDUFA action date scheduled for September 26, 2024.  

Today, we're going to take a look at vitamin B1, also known as thiamine. Vitamin B1 is intimately involved with the function of the mitochondria, so if you're deficient, low energy is one of the first symptoms. The more carbs and sugar you consume, the more B1 you need. This is because vitamin B1 is necessary to burn glucose. Even on a ketogenic diet, you'll still burn glucose for certain functions of the body. Vitamin B1 is water soluble, so it isn't stored in the body for long periods. This makes it easier to become deficient. B1 is also important for the myelin sheath—the coating on your nerves. B1 is crucial for the proper function of the autonomic nervous system and specifically affects the vagus nerve. The following conditions and symptoms are related to a deficiency in vitamin B1: •Gastroparesis (slow digestive system) •GERD •Peripheral neuropathy •Regurgitation of bile •Excessive sweating or no sweating at all •Excessive tears or no tears at all •Dizziness when standing up •Irritability •Low tolerance for stress •Trouble regulating body temperature •Increased pulse rate If you have a more severe B1 deficiency, you might experience the following: •Enlarged heart •Edema •Confusion •Memory loss •Nystagmus •Ataxia •Hearing loss •Sleep apnea •Trouble breathing Avoid synthetic B1, which is sometimes made with hydrochloric acid, acetone, ammonia, and coal tar. Allithiamine and benfotiamine are the two best options for vitamin B1 supplements. Drugs can also affect the absorption of vitamin B1. Metformin, diuretics, and certain antibiotics can lead to vitamin B1 deficiency. Low magnesium can affect vitamin B1 absorption as well. Download the Summary of ALL the Functions of Vitamin B1: https://drbrg.co/3tGUuu0

Understanding the hemodynamic consequences and cardiovascular parameters in aortic regurgitation is a tough pill to swallow for many people. In this short podcast, I address this question and also make common NBME integrations with this topic (like cardiac output, pulse pressures, systemic pressures, renin-angiotensin-system, etc). I explain all the pathophysiology step by step so you … Continue reading Divine Intervention Episode 496: Aortic regurgitation and some USMLE integrations