POPULARITY
This week, we cover a range of topics: urinary vs cervical HPV collection, the benefits and harms of Tramadol, whether patients need anticoagulation after successful ablation for afib, and the ongoing value of COVID vaccines in the omicron era. Plus a quiz: is TAVR now indicated for everyone with severe aortic stenosis? Stay tuned!
A special, interactive Doc Talk event recorded live in front of an audience at The Monument in Rapid City in honor of Valve Disease Awareness Day. Joseph Tuma, M.D., FACC, FSCAI, Interventional Cardiologist at Heart and Vascular Institute leads a discussion in which guests and audience members alike share stories of their Transcatheter Aortic Valve Replacement (TAVR) procedures.Don't miss out on one of our most unique and informative Doc Talks yet. Hosted on Acast. See acast.com/privacy for more information.
EVOLUT Low Risk data, a provocative meta-analysis, DNR orders, targeted hypothermia, good news in HFpEF evidence, and GLP-1s as AF drugs are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I EVOLUT Low Risk 6-year Results and a 5-year Meta-Analysis of TAVR vs SAVR 6-Year Outcomes of TAVR vs SAVR https://www.jacc.org/doi/10.1016/j.jacc.2026.02.5063 EVOLUT Low Risk Trial at 2 years https://www.nejm.org/doi/full/10.1056/NEJMoa1816885 EVOLUT Low Risk Trial at 3 years https://www.jacc.org/doi/10.1016/j.jacc.2023.02.017 EVOLUT Low Risk Trial at 4 years https://www.jacc.org/doi/10.1016/j.jacc.2023.09.813 Nonproportional Hazards for Time-to-Event Outcomes in Clinical Trials https://www.jacc.org/doi/10.1016/j.jacc.2019.08.1034 TAVR vs SAVR 5-Year Outcomes - Systematic Review https://heart.bmj.com/content/early/2026/02/11/heartjnl-2025-327092 TAVR vs SAVR Updated Meta-Analysis of RCTs https://www.jacc.org/doi/10.1016/j.jacc.2024.12.031 UK TAVI Trial https://jamanetwork.com/journals/jama/fullarticle/2792251 Dr David Cohen on X https://x.com/djc795/status/2023556582030852172?s=46&t=zXMCUoVjSsdyemzWlzeBjA II DNR in the Hospital Inadequate Documentation of Unilateral DNR Orders https://jamanetwork.com/journals/jama/fullarticle/2829203 GeriPal Blog Unilateral DNR Orders https://geripal.org/unilateral-dnr-gina-piscitello-erin-demartino-will-parker/ III Yet another failure of Targeted Hypothermia 2-Year Follow-Up of TTM2 Trial https://jamanetwork.com/journals/jamaneurology/fullarticle/2845193 TTM2 Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2100591 IV Good news in HFpEF Evidence ALT-FLOW II Trial https://doi.org/10.1093/ejhf/xuaf016 V GLP-1 as AF drugs Semaglutide as Adjunctive Therapy in Obesity-Related PAF https://doi.org/10.1093/europace/euag018 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
Dr. Peter Fail and Dr. Shane Prejean break down structural heart and valve disease - including what it is, common warning signs, and advanced treatment options that can improve quality of life for patients, such as Transcatheter Aortic Valve Replacement (TAVR), as well as their recent milestone of completing their 1,000th TAVR.Visit www.cardio.com for more information or to schedule an appointment with one of our providers.
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning spoke with Dr. Louise Kenny, a consultant pediatric and adult congenital cardiothoracic and transplant surgeon at Freeman Hospital in Newcastle upon Tyne, England, about congenital heart transplants. Chapters 00:00 Intro 02:24 JANS 1, VECTOR Procedure 07:38 JANS 2, Combined Inflation & Cooling 08:26 JANS 3, Caring for VIP Patients 11:43 JANS 4, Country Wealth & Min Inv Correlation 12:57 Career Center 13:37 Video 1, Debranching AAV Step-by-Step 15:14 Video 2, Abramson Technique 16:59 Video 3, Min Inv Cardiac w Dr. Chitwood 18:54 Dr. Kenny, DCD-HOPE Congenital Transplant 31:58 CKD & CSA-AKI Podcast Episode 34:12 Upcoming Events 35:13 Closing They discussed the complexities surrounding congenital heart transplants, donation after brain death (DBD), and donation after circulatory death (DCD). They also explored the benefits of hypothermic oxygenated perfusion (HOPE) for children, particularly in DCD pediatrics patients, and highlighted the first case where this model was used. Additionally, they examined the future of HOPE and its potential for more complex procedures. Moreover, they discussed implanting ventricular assist devices (VAD) in children, along with what other countries are doing regarding congenital heart transplants, including ongoing studies in this field. Joel also highlights recent JANS articles on the first human VECTOR procedure for percutaneous aorto-coronary bypass graft to prevent coronary obstruction following TAVR, combined inflation and cooling method improves lung function in uncontrolled donation after circulatory death, caring for VIP patients in cardiothoracic surgery, and the national wealth and the global spread of minimally invasive thoracic surgery. In addition, Joel explores a step-by-step guide for debranching of aortic arch vessels through a cervical approach for aortic arch aneurysm, a master class with Horacio Abramson on the Abramson technique, and an episode of The Atrium podcast featuring host Dr. Alice Copperwheat speaking with Dr. Randolph Chitwood about the future of minimally invasive cardiac surgery. Before closing, Joel highlights upcoming events in CT surgery. JANS Items Mentioned 1.) Percutaneous Aorto-Coronary Bypass Graft to Prevent Coronary Obstruction Following TAVR: First Human VECTOR Procedure 2.) Combined Inflation and Cooling Method Improves Lung Function in Uncontrolled Donation After Circulatory Death 3.) Caring for VIP Patients in Cardiothoracic Surgery: Navigating Bias, Pressure, and Protocol 4.) National Wealth and the Global Spread of Minimally Invasive Thoracic Surgery: Insights From the European Society of Thoracic Surgeons Database CTSNet Content Mentioned 1.) Debranching of Aortic Arch Vessels Through a Cervical Approach for Aortic Arch Aneurysm: A Step-by-Step Guide 2.) Master Class: The Abramson Technique With Horacio Abramson and Joel Dunning 3.) The Atrium: The Future of Minimally Invasive Cardiac Surgery Other Items Mentioned 1.) HOPE for Children: Successful Pediatric DCD Heart Transplantation Using Hypothermic Oxygenated Perfusion 2.) Instructional Video Competition 3.) Career Center 4.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.
Send us a textSt. Luke's introduced TAVR – catheter-based replacement of the aortic valve – to Cedar Rapids, performing the area's first procedure in 2016. Since then, the heart team has performed nearly 800 TAVRs. Joining the podcast to talk about the procedure are Dr. Richard Kettelkamp and Katie Maybanks, ACNP, from St. Luke's structural cardiology team. To learn more about heart care services at St. Luke's, Cedar Rapids' Heart Hospital, visit unitypoint.org/cr-heart. Do you have a question about a trending medical topic? Ask Dr. Arnold! Submit your question and it may be answered by Dr. Arnold on the podcast! Submit your questions at: https://www.unitypoint.org/cedarrapids/submit-a-question-for-the-mailbag.aspxIf you have a topic you'd like Dr. Arnold to discuss with a guest on the podcast, shoot us an email at stlukescr@unitypoint.org.
Listener feedback, the value of procedural volume for TAVR and MTEER, ventricular arrhythmia in older athletes, and the Goldilocks time horizon for predicting and modifying CV risk are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Procedural Volume and Outcomes for TAVI and M-TEER Operator Procedural Volumes and Outcomes for TAVR and MTEER https://jamanetwork.com/journals/jamacardiology/fullarticle/2843740 II Ventricular Arrhythmia in Older Male Endurance Athletes Myocardial Fibrosis May Raise Arrhythmia Risk in Older Male Endurance Athletes https://www.medscape.com/viewarticle/myocardial-fibrosis-may-raise-arrhythmia-risk-older-male-2026a10001y0 Timing and Relationship of VA With Exercise Patterns in Older Male Endurance Athletes https://doi.org/10.1093/eurjpc/zwag021 III Predicting Cardiac Risk and Statin Use 30-Year ASCVD Risk Among US Adults Aged 30-59 https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.125.012348 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251386377
On this episode of the Donut of Destiny, hosts Sotirios Evangelou, MD, FSCCT and Nisha Hosadurg , MBBS speak with guest Alan Vainrib, MD on how computational fluid dynamics (CFD) is emerging as a powerful research tool for understanding blood-flow behavior in structural heart disease. Using CT/MRI-based models, CFD can simulate pressures, velocities, shear stress and even post-procedure hemodynamics — offering new possibilities for evaluating aortic stenosis, planning TAVR and guiding mitral, tricuspid and LAAO interventions.
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning spoke with Dr. Randas Batista, cardiac surgeon and founder of Vilela Batista Heart Foundation, about the surgical treatment of Eisenmenger syndrome. Chapters 00:00 Intro 02:51 JANS 1, DAMSUN-HF Study 05:41 JANS 2, TAVR vs SAVR Guidelines 07:45 JANS 3, Myocardial Infarction After CABG 10:31 JANS 4, VAD Bridge-to-Transplant 12:27 New Recruitment Guide 13:54 Video 1, Anomalous Right Coronary Artery 15:27 Video 2, Beating Heart Transplant OCS 17:51 Video 3, Aortic Dissection Podcast w Marc Moon 19:26 Randas Batista Interview 37:38 Upcoming Events They explored what Eisenmenger syndrome is and outlined the most common causes of the condition. They also delved into the history of this syndrome, highlighting the significant contributions of Viktor Eisenmenger and Paul H. Wood. Furthermore, they discussed the impact of this syndrome on lung function and extracting oxygen within the pulmonary artery. Dr. Batista shared valuable technical tips for performing the surgical procedure as well as solutions for managing this syndrome. Joel also highlights recent JANS articles on the DAMSUN-HF study on AI-enabled digital auscultation for detecting heart failure with reduced ejection fraction in Sub-Saharan Africa, transcatheter or surgical aortic-valve replacement in low-risk patients at seven years, current clinical practices and future perspectives on periprocedural myocardial infarction after coronary artery bypass grafting, and an analysis of UNOS. In addition, Joel explores anomalous right coronary artery, beating heart transplantation using the Organ Care "Heart-in-a-Box" System (OCS), and an episode of The Atrium podcast featuring host Dr. Alice Copperwheat speaking with Dr. Marc Moon about aortic dissection. Before closing, Joel highlights upcoming events in CT surgery. JANS Items Mentioned 1.) AI-Enabled Digital Auscultation for Detecting Heart Failure With Reduced Ejection Fraction in Sub-Saharan Africa: The DAMSUN-HF Study 2.) Transcatheter or Surgical Aortic-Valve Replacement in Low-Risk Patients at 7 Years 3.) Periprocedural Myocardial Infarction After Coronary Artery Bypass Grafting: Current Clinical Practices and Future Perspectives 4.) Analysis of UNOS: Ventricular Assist Device as Bridge-to-Transplant in Paediatric Patients With Congenital Heart Disease CTSNet Content Mentioned 1.) Anomalous Right Coronary Artery 2.) Beating Heart Transplantation Using the Organ Care "Heart-in-a-Box" System (OCS) 3.) The Atrium: Aortic Dissection Other Items Mentioned 1.) The Cardiac Recovery Room 2.) Resident Video Competition 3.) 2025 CTSNet Recruitment Guide 4.) Career Center 5.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.
Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826251336314
For patients with aortic stenosis, is earlier intervention beneficial? Mamas Mamas, Philippe Généreux, Nicolas Van Mieghem, and Bernard Prendergast discuss.
Aaysha Cader, MD MSc, social media editor for JACC: Cardiovascular interventions and Josep Rodés-Cabau, MD, PhD discuss the Impact of Early Hemodynamic Valve Deterioration on Long-term Outcomes Following Transcatheter Aortic Valve Replacement, published in the October 27 issue of the journal.
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning explores the integration of artificial intelligence (AI) in writing medical articles. Chapters 00:00 Intro 01:56 Using AI in Medical Writing 09:07 JANS 1, AI-Writing Article 14:53 JANS 2, Kidney vs Lung Transplant Outcomes 17:04 JANS 3, Harvesting Tech on ITAG 18:56 JANS 4, Phase 2 NeoCOAST-2 Trial 23:01 Career Center 23:41 Video 1, TAVR Explant After CABG w MVR 25:28 Video 2, Updated Y-Incision AA Enlargement 27:05 Video 3, Carotid Artery Cann for CABG 28:16 Upcoming Events He reviews guidelines set by the International Committee of Journal Editors Committee regarding publication ethics and emphasizes the benefits of utilizing AI in writing processes. Joel also highlights the crucial necessity of including disclosures when employing AI tools. Additionally, he delves into other ways AI can be used, such as data analysis, and discusses taking accountability when using these technologies. Furthermore, he addresses the limitations of AI, noting that it cannot be cited as a source or used as a coauthor. Joel also highlights recent JANS articles on assisted artificial intelligence in medical writing, the impact of kidney transplantation on survival outcomes for lung transplantation, if the harvesting technique affects the production of nitric oxide and endothelin in the internal thoracic artery graft, and the platform phase 2 NeoCOAST-2 trial on perioperative durvalumab plus chemotherapy plus new agents for resectable non-small-cell lung cancer. In addition, Joel explores a TAVR explant after CABG with MVR, tips and tricks for the updated Y-incision aortic annular enlargement, and carotid artery cannulation for cardiopulmonary bypass in minimally invasive cardiac surgery. JANS Items Mentioned 1.) Assisted Artificial Intelligence in Medical Writing: A Primer for Humans 2.) The Impact of Kidney Transplantation on Survival Outcomes for Lung Transplantation 3.) The Harvesting Technique Affects the Production of Nitric Oxide and Endothelin in the Internal Thoracic Artery Graft 4.) Perioperative Durvalumab Plus Chemotherapy Plus New Agents for Resectable Non-Small-Cell Lung Cancer: The Platform Phase 2 NeoCOAST-2 Trial CTSNet Content Mentioned 1.) TAVR Explant After CABG With MVR 2.) Tips and Tricks for the Updated Y-Incision Aortic Annular Enlargement 3.) Carotid Artery Cannulation for Cardiopulmonary Bypass in Minimally Invasive Cardiac Surgery Other Items Mentioned 1.) Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly work in Medical Journals 2.) Perfecting TAVR Removal | Skills Sharpening With Vince Gaudiani 3.) Resident Video Competition 4.) Career Center 5.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with Dr. Fraser Sutherland, a consultant cardiac surgeon at Ross Hall Hospital and the Golden Jubilee National Hospital, Scotland, about the world's first transcervical robotic aortic valve replacement (AVR) procedures. Chapters 00:00 Intro 02:30 JANS 1, CABG After 60 Years 13:53 JANS 2, Endovascular Arch Repair 16:45 JANS 3, Impact of Age on ARR 18:47 JANS 4, Anterior Mediastinal Teratomas 20:28 Career Center 21:02 Video 1, RUL Without Dissecting SPV 22:58 Video 2, Replacement w Double Patch Repair 23:53 Video 3, TAVR & SAVR Removal w LVOR 24:47 Dr. Sutherland Interview 45:26 Closing They discuss the history and evolution of these cases, along with the preclinical work that led to this innovative technique. Dr. Sutherland addresses initial challenges such as the uniportal incision, the transcervical retractor system, and enhancing dexterity by incorporating a robotic system. They also detail the first clinical case, including postoperative outcomes and the importance of maintaining safety for the patient. Additionally, they explore the benefits for patients undergoing this procedure and its future potential. Furthermore, Dr. Sutherland provides insights into the procedural steps and key aspects of the procedure. Joel also highlights recent JANS articles on coronary artery bypass grafting 60 years after its debut, endograft design options and worldwide results for endovascular arch repair, the impact of age on aortic root replacement, and a multicenter retrospective study on if subxiphoid thoracoscopic surgery is safe and feasible for the treatment of anterior mediastinal teratomas. In addition, Joel explores a multiportal approach for robotic right upper lobectomy without dissecting the superior pulmonary vein, aortic and mitral replacement with double patch repair, and TAVR and SAVR removal with left ventricular outflow reconstruction. JANS Items Mentioned 1.) Coronary Artery Bypass Grafting: 60 Years After Its Debut 2.) Endovascular Arch Repair: Endograft Design Options and Worldwide Results 3.) The Impact of Age on Aortic Root Replacement 4.) Subxiphoid Thoracoscopic Surgery Is Safe and Feasible for the Treatment of Anterior Mediastinal Teratomas: A Multicentre Retrospective Study CTSNet Content Mentioned 1.) Robotic Right Upper Lobectomy Without Dissecting the Superior Pulmonary Vein: A Multiportal Approach 2.) Aortic and Mitral Replacement With Double Patch Repair 3.) TAVR and SAVR Removal With Left Ventricular Outflow Reconstruction Other Items Mentioned 1.) World's First Transcervical Robotic AVR Procedures Successfully Performed in 4 Cleveland Clinic Patients 2.) Resident Video Competition 3.) Perfecting TAVR Removal | Skills Sharpening With Vince Gaudiani 4.) Career Center 5.) CTSNet Events Calendar Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Outcomes of Telemedicine TAVR Preoperative Evaluations.
Examining the claim that cabbage family vegetables are bad for the thyroid; Walmart announces sweeping move to reformulate its products without synthetic dyes, sketchy additives; Under Congressional questioning, Google admits to censoring contrary narratives on YouTube during Covid; Children garner psychological benefits from grandparent time; J&J fined nearly $1 billion in landmark talc baby powder lawsuit; Humans are among the few animals who can't make their own vitamin C—why that may be a good thing.
In the September 22 episode of JACC This Week, Editor-in-Chief Dr. Harlan Krumholz explores the concept of "computable quality" in healthcare, advocating for real-time, data-driven improvement in clinical care. He reviews original research on pop-up cardiovascular screenings in pharmacies and sporting events, AI-driven echocardiographic automation, and anticoagulation in pulmonary arterial hypertension. The episode also features a three-part debate on transcatheter aortic valve replacement (TAVR) in low-risk patients, highlighting evolving evidence, clinical implications, and calls for guideline reassessment. Tune in for insights on innovation, equity, and the future of cardiovascular care.
Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Ideal Navitor Implant Depth for Redo-TAVR Feasibility and Coronary Access: A CT Simulation Study.
Medsider Radio: Learn from Medical Device and Medtech Thought Leaders
In this episode of Medsider Radio, we sat down with Ahmed Elmouelhi, CEO of TRiCares. TRiCares is developing Topaz, the first purpose-built transcatheter tricuspid valve replacement system — a technology designed specifically for the right side of the heart, where complex anatomy has made durable solutions elusive.Ahmed is a 20-year medtech veteran with leadership experience across electrophysiology, men's health, neuromodulation, and structural heart. Before joining TRiCares, he helped build multiple businesses at AtriCure and held key roles at Medtronic during the early days of TAVR. He also serves as Chairman of the American Heart Association in Minnesota.In this interview, Ahmed shares why adoption — not added complexity — is the ultimate measure of medtech innovation, how a small group of physician champions can accelerate clinical studies faster than internal resources alone, and why treating your board like collaborators in the “sandbox” leads to stronger partnerships and better outcomes.Before we dive into the discussion, I wanted to mention a few things:First, if you're into learning from medical device and health technology founders and CEOs, and want to know when new interviews are live, head over to Medsider.com and sign up for our free newsletter.Second, if you want to peek behind the curtain of the world's most successful startups, you should consider a Medsider premium membership. You'll learn the strategies and tactics that founders and CEOs use to build and grow companies like Silk Road Medical, AliveCor, Shockwave Medical, and hundreds more!We recently introduced some fantastic additions exclusively for Medsider premium members, including playbooks, which are curated collections of our top Medsider interviews on key topics like capital fundraising and risk mitigation, and 3 packages that will help you make use of our database of 750+ life science investors more efficiently for your fundraise and help you discover your next medical device or health technology investor!In addition to the entire back catalog of Medsider interviews over the past decade, premium members also get a copy of every volume of Medsider Mentors at no additional cost, including the latest Medsider Mentors Volume VII. If you're interested, go to medsider.com/subscribe to learn more.Lastly, if you'd rather read than listen, here's a link to the full interview with Ahmed Elmouelhi.
Commentary by Dr. Jian'an Wang.
The lecture will examine the pros and cons of democracy in today's world, focusing on the importance of domestic and international rule of law to maintain democratic ideals, which are fragile in times of conflict. There will be examples given, highlighting the current War in Ukraine and the political situation in the United States, the influence of other players and the legacy of the Cold War.Lastly, there will be an observation on the ways that the principal judicial organs operate, their challenges, and a prediction of their future. Sir Howard Morrison will provide some suggestions as to how things might be contained by means of persuasive soft power.This lecture was recorded by Howard Morrison on the 9th of June 2025 at Barnard's Inn Hall, London.Sir Howard Morrison KC was called to the Bar by Grays Inn in 1977. He is now a Master of the Bench. He was commissioned as a TAVR infantry officer. He practised on the Midland and Oxford Circuit until 1986 when he went to Fiji as a Resident Magistrate , later promoted Chief Magistrate and Senior Magistrate of Tuvalu. Appointed OBE for services to the judiciary following military coups. He then served as Attorney General for Anguilla before returning to UK practice at 1 King's Bench Walk. He was appointed Recorder sitting in crime, civil and family and defended at the United Nations Criminal Tribunals for the Former Yugoslavia in The Hague and the Rwanda Tribunal in Arusha in Tanzania before taking Silk in 2001 and was subsequently appointment to the Circuit Bench in 2004.In 2005 he was seconded to advise the judges of the Iraqi Higher Tribunal trying Saddam Hussein, spending a year in Baghdad after which he was appointed CBE. In 2009 he was appointed as the UK Judge for the Special Tribunal for the Lebanon and then as the UK Judge for the Yugoslavia Tribunal where he was a trial judge in the seminal case of Radovan Karadzic. In 2011 he was elected as the UK Judge at the International Criminal Court until 2021 where he served two terms as President of the Appeals Chamber being appointed KCMG in 2016. He is a Senior Fellow of the Lauterpacht Centre of Cambridge University and a visiting professor at the universities of Leicester ( appointed Hon LLD), Warwick and Northumbria. He has lectured in international criminal and humanitarian law at some 25 universities worldwide. He is currently an associate tenant at Doughty Strert chambers, the UK Independent Advisor to the Ukrainian Prosecutor General, President of the Court of Appeal of the British Indian Ocean Territories and trains counter-terrorism judges and prosecutors in Iraq.The transcript of the lecture is available from the Gresham College website: https://www.gresham.ac.uk/watch-now/grays-inn-25Gresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham College's mission, please consider making a donation: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-today Website: https://gresham.ac.ukX: https://x.com/GreshamCollegeFacebook: https://facebook.com/greshamcollegeInstagram: https://instagram.com/greshamcollegeBluesky: https://bsky.app/profile/greshamcollege.bsky.social TikTok: https://www.tiktok.com/@greshamcollegeSupport Us: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-todaySupport the show
Giuseppe Tarantini, MD, PhD and Mirza Umair Khalid, MBBS, MD, FACC discuss the Coronary Access After TAVI (CAvEAT) Study.
In this episode, our hosts are joined by Sabine Bleiziffer and Augusto D'Onofrio to discuss SAVR after TAVR - exploring key decision-making factors, including valve selection, explantation techniques, and patient-specific risk profiles. The guests share experiences with challenging cases, technical tips, and thoughts on how procedural volume, planning, and shared decision-making can impact outcomes. We also consider the future of lifetime valve management and what young surgeons need to know as this field continues to evolve.
JACC's July 29 issue explores why the ACURATE neo2 valve failed in its IDE trial, with a post-hoc analysis pointing to under-expansion in heavily calcified anatomies as a potential culprit. Though the valve is off the market, the findings raise critical questions about procedural success, device design, and future innovation in TAVR. Listen to our Deep Dive narrated by JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC, as he goes into the science behind the peer review.
In this episode, Thomas Draper, Vice President of the Wellstar Center for Cardiovascular Care, joins Becker's to discuss how Transcatheter Aortic Valve Replacement (TAVR) has evolved into a cornerstone of structural heart programs. Tom shares how Wellstar built a multidisciplinary infrastructure around TAVR, leveraged data and AI to identify underserved patients, and embraced technology to maintain quality amid rapid growth. Tune in to hear how the expansion of TAVR indications, AI integration, and patient-centered strategy are shaping the future of cardiovascular care.This episode is sponsored by Edwards Lifesciences.
Supra-Annular Vs. Intra-Annular Devices For TAVR-in-TAVR: The Pandora International Registry
Evaluating Coronary Access After TAVR With The 4th And 5th -generation Self-expanding Valves - The EPROMPT-CA Study
The FDA approval of TAVR for asymptomatic AS, digital health, subcutaneous vs transvenous ICD, and cryptogenic stroke in young adults are discussed by John Mandrola, MD. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I FDA announces approval for TAVR in pts with asymptomatic AS Edwards Press Release https://www.edwards.com/newsroom/news/2025-05-01-edwards-tavr-receives-fda-approval-for-patients-with-asymptomatic-severe-aortic-stenosis Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis (EARLY TAVR) https://www.nejm.org/doi/full/10.1056/NEJMoa2405880 EARLY TAVR: A Positive Trial That Fails to Inform Clinical Decisions https://www.medscape.com/viewarticle/early-tavr-positive-trial-fails-inform-clinical-decisions-2024a1000kec Asymptomatic Aortic Stenosis: 'Time to Act' or Not So Fast? https://www.medscape.com/viewarticle/asymptomatic-aortic-stenosis-time-act-or-not-so-fast-2025a10005o9 II PPG that Can Distinguish source of Tachycardia Machine-learning guided differentiation between photoplethysmography waveforms of supraventricular and ventricular origin https://doi.org/10.1016/j.cmpb.2025.108798 III PRAETORIAN -XL trial Device-related Complications in Transvenous Versus Subcutaneous Defibrillator Therapy During Long-term Follow-up: the PRAETORIAN-XL Trial https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.074576 Subcutaneous or Transvenous Defibrillator Therapy (PRAETORIAN trial) https://www.nejm.org/doi/full/10.1056/NEJMoa1915932 Subcutaneous or Transvenous Defibrillator Therapy Letter to Editor https://www.nejm.org/doi/full/10.1056/NEJMc2034917 The PRAETORIAN Trial: Guarded Approach to Subcutaneous ICD Best https://www.medscape.com/viewarticle/937156 IV Stroke in Young People Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale https://www.ahajournals.org/doi/10.1161/STROKEAHA.124.049855 Migraine: A Key Factor in Young Adults With Unexplained Stroke https://www.medscape.com/viewarticle/migraine-key-factor-young-adults-unexplained-stroke-2025a10009jj U.S. stroke rate declining in adults 75 and older, yet rising in adults 49 and younger ASA statement https://newsroom.heart.org/news/u-s-stroke-rate-declining-in-adults-75-and-older-yet-rising-in-adults-49-and-younger Increasing stroke in the young https://doi.org/10.1016/j.ajpc.2020.100085 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
The FAME 3 trial 5-year results, TAVR at 5 years, pacers after TAVR, and mavacamten not a wonder drug are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I FAME 3 at Five Years Stents as Good as Surgery for Triple-Vessel Disease https://www.medscape.com/viewarticle/noninvasive-stents-good-surgery-triple-vessel-disease-2025a10007l4 Main trial NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2112299 Circulation 3-years https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.065770 5-year results Lancet 10.1016/S0140-6736(25)00505-7 https://linkinghub.elsevier.com/retrieve/pii/S0140673625005057 II TAVR in Low-Risk Patients at 5 years 5-Year TAVR, Surgery Outcomes Similar in Low-Risk Patients https://www.medscape.com/viewarticle/5-year-tavr-surgery-outcomes-similar-low-risk-patients-2025a10007zl EVOLUT Low-Risk 5 years https://www.jacc.org/doi/10.1016/j.jacc.2025.03.004 EVOLUT Editorial – We're Halfway There https://www.jacc.org/doi/10.1016/j.jacc.2025.03.428 PARTNER 3 Low-Risk https://www.nejm.org/doi/full/10.1056/NEJMoa2307447 NOTION at 5 years https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.036606 III The Matter of Pacemakers After TAVI JACC IV Study Badertscher https://www.jacc.org/doi/10.1016/j.jcin.2025.03.028 Assessing the quality of reporting of harms in randomized controlled trials published in high impact cardiovascular journals IV Mavacamten Looks to Have Specific Indications EXPLORER HCM 10.1016/S0140-6736(20)31792-X External Link VALOR HCM https://jamanetwork.com/journals/jamacardiology/fullarticle/2809050 BMS Press Release https://news.bms.com/news/details/2025/Bristol-Myers-Squibb-Provides-Update-on-Phase-3-ODYSSEY-HCM-Trial/ FINAL THOUGHTS PRAGUE 25 https://bmjopen.bmj.com/content/12/6/e056522 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
Program notes:0:33 TAVR outcomes improved1:33 Dapagliflozin 2:33 Looked at comorbidities3:00 Tolebrutinib for relapsing MS4:00 Annualized relapse rate5:00 Works in the CNS6:00 First endpoint wasn't proven6:20 Invasive group A strep7:20 Become more resistant to antibiotics8:01 Not a single type of group A strep8:25 Hearing loss and heart failure9:25 Psychological distress mediiates10:25 With hearing aids, you would think it would go down11:20 Everything looks associated12:03 End
In this podcast, Dr. Valentin Fuster reviews a pivotal study comparing the five-year outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in low-risk patients with severe aortic stenosis. The study found that both treatments yielded similar mortality and stroke rates, reinforcing TAVR's non-inferiority to surgery, though long-term outcomes in younger patients and the impact of pacemaker implantation remain areas of concern.
In this podcast, Dr. Valentin Fuster presents a comprehensive review of conduction disturbances following transcatheter aortic valve replacement (TAVR), highlighting key factors that contribute to the need for permanent pacemaker implantation. The discussion covers current management strategies, risks, and future perspectives, emphasizing the need for improved prediction methods and the evolving role of ambulatory monitoring and physiological pacing techniques.
I'm delighted to bring you Episode 4 of Season 3 of The Luke Coutinho Show, featuring Dr. Maulik Parekh—a leading Interventional Cardiologist, Head of the TAVR and Structural Heart Programme, and Consultant at the Sir H. N. Reliance Foundation Hospital and Research Centre.Tune in to discover:Dr. Maulik's journey into cardiology: From aspiring architect to pioneering cardiologist, and healing through groundbreaking structural heart interventions for all agesUnderstanding the rising incidence of heart diseases: Why India is facing an alarming rise in heart issues among the young, driven by genes, lifestyle, and stressGenetics vs. Epigenetics: How can you outsmart your family history with the right choicesPreventive heart health: Recommended screenings for all age groups and mindful use of health tracking devicesImpact of chronic stress and emotions on heart health: How stress and emotions can disrupt rhythms, weaken muscles, and turn minor plaques into major heart attacksMeditation and body awareness: Learn to deepen your connection to heart health by enhancing sensitivity to your body's pulse and cardiovascular stateVaping, stimulants, and heart health: Vaping and stimulants hijack your heart's natural rhythm, leading to long-term cardiac stress and dysfunctionAnd much more…Chapters:00:00 - Introduction and Dr. Maulik's Journey06:55 - Rise in Young Heart Attacks10:35 - Genetics vs. Epigenetics13:23 - Essential Heart Health Screenings20:09 - Health Gadgets: Helpful or Stressful?23:51 - Dr. Maulik's Personal Health Routine30:26 - How Stress Damages Your Heart34:38 - Broken Heart Syndrome Explained37:06 - Meditation and Body Awareness40:28 - Vaping, Stimulants & Heart Health44:26 - The Four C's for Heart Health
Makoto Mori, MD, JACC: Associate Editor, is joined by author John K. Forrest, MD, FACC, discussing this study from Forrest et al presented at ACC.25 and published in JACC. Patients with severe aortic stenosis who were treated with either a supraannular self-expanding TAVR or surgery showed comparable rates of all-cause mortality and disabling stroke at 5 years, strengthening TAVR as a safe, effective, and durable alternative to surgery for patients, regardless of their surgical risk.
In this podcast, Dr. Valentin Fuster presents a study evaluating the five-year outcomes of Transcatheter Aortic Valve Replacement (TAVR) versus surgical aortic valve replacement in high-risk patients. The study shows that TAVR leads to significantly better valve performance but highlights that both procedures' long-term success is hindered by bioprosthetic valve dysfunction, underscoring the need for individualized treatment strategies and longer follow-up studies.
In this episode, Dr. Valentin Fuster presents key findings from the April 8, 2025 issue of the Journal of the American College of Cardiology, covering three groundbreaking studies. Topics include the newly defined threshold for mild aortic stenosis using MRI, the relationship between heat wave exposure and cardiac mortality, and the long-term outcomes of aortic valve performance in patients undergoing TAVR versus surgery.
In this podcast highlights the growing concern over transcatheter valve failure following transcatheter aortic valve replacement (TAVR), emphasizing the need for standardized imaging protocols and frequent follow-ups. Experts discuss best practices for monitoring and managing these patients, urging collaborative international efforts to validate new imaging techniques and improve patient outcomes.
Listener feedback on asymptomatic aortic stenosis (AS), transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR), coronary artery calcium (CAC), and revascularization for patients with ischemic LV dysfunction are discussed by John Mandrola, MD, in today's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Aortic Valve Intervention for Asymptomatic AS Asymptomatic Aortic Stenosis: “Time to Act” or Not So Fast? https://www.medscape.com/viewarticle/asymptomatic-aortic-stenosis-time-act-or-not-so-fast-2025a10005o9 EARLY TAVR: A Positive Trial That Fails to Inform Clinical Decisions https://www.medscape.com/viewarticle/early-tavr-positive-trial-fails-inform-clinical-decisions-2024a1000kec Reddy et al: https://doi.org/10.1016/j.jacc.2024.12.031 Wallach editorial https://doi.org/10.1016/j.jacc.2025.01.020 Guerrero https://www.tctmd.com/slide/tavr-young-patients-current-treatment-patterns-us II CAC - Coronary Artery Calcium Coronary Artery Calcium Testing—Too Early, Too Late, Too Often https://jamanetwork.com/journals/jamacardiology/fullarticle/2830950 CAUGHT-CAD https://jamanetwork.com/journals/jama/fullarticle/2831115 III CABG, PCI or Meds for Ischemic LV Dysfunction STICH https://www.nejm.org/doi/full/10.1056/NEJMoa1100356 STICHES https://www.nejm.org/doi/full/10.1056/NEJMoa1602001 REVIVED BCIS https://www.nejm.org/doi/full/10.1056/NEJMoa2206606 EHJ paper https://doi.org/10.1093/eurheartj/ehaf080 IV Preview https://www.medscape.com/viewarticle/shed-lead-and-injuries-should-cath-labs-go-lead-free-2024a1000hnb You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net
In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.
In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.
In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.
In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.
In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.
In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.
Join us as we review recent practice-changing articles on a new triple pill for hypertension, how arm position affects blood pressure, early TAVR for asymptomatic patients with severe AS, liberal versus restrictive transfusion strategy in patients with acute brain injury, and a quick overview of the 2024 ACC/AHA perioperative medicine guidelines. Fill your brain hole with a delicious stack of tofurkey cakes! Featuring Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), Jen DeSalvo (@drjendesalvo), and Matt Watto (@doctorwatto). Claim CME for this episode at curbsiders.vcuhealth.org! Episodes | Subscribe | Spotify | Swag! |Mailing List | Contact | CME! Credits Written and Hosted by: Rahul Ganatra MD, MPH; Jen DeSalvo MD; Paul Williams, MD, FACP, Matthew Watto MD, FACP Cover Art: Matthew Watto MD, FACP Reviewer: Rahul Ganatra MD, MPH Technical Production: Pod Paste Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Show Segments Intro, disclaimer A new triple pill for hypertension How arm position affects blood pressure Early TAVR for asymptomatic patients with severe AS Liberal versus restrictive transfusion strategy in patients with acute brain injury A quick overview of the 2024 ACC/AHA perioperative medicine guidelines Outro Sponsor: Freed You can try Freed for free right now by going to freed.ai. And listeners of Curbsiders can use code CURB50 for $50 off their first month. Sponsor: AquaTru Today listeners receive 20% off any AquaTru purifier! Just go to AquaTru.com and enter code “CURB“ at checkout. Sponsor: Uncommon Goods To get 15% off your next gift, go to uncommongoods.com/curb.