Podcasts about PFA

Listener feedback on mechanical CPR devices, PFA and stroke, the Lindy effect in adopting new technology, and an ESC preview are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback on Mechanical Compression Devices for OHCA   Mechanical CPR Device Use and Cardiac Arrest Survival https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.126.079272 PARAMEDIC trial https://www.thelancet.com/article/S0140-6736(14)61886-9/fulltext CIRC trial https://www.resuscitationjournal.com/article/S0300-9572(14)00128-2/fulltext LINC trial https://jamanetwork.com/journals/jama/fullarticle/1774037 Cochrane Review – Mechanical vs Manual Chest Compressions for Cardiac Arrest https://pmc.ncbi.nlm.nih.gov/articles/PMC6953326/ II PFA and Stroke Risk of Stroke and TIA With PFA vs RF Ablation https://www.ahajournals.org/doi/epub/10.1161/CIRCULATIONAHA.126.081092 AVANT GUARD Trial https://www.nejm.org/do/10.1056/NEJMdo008538/full/ EMBOL-AF Registry https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehag217/8566008 III A New ICD Lead LEADR LBBAP Trial https://doi.org/10.1016/j.hrthm.2026.08.030 IV ESC Preview Mandrola's Preview of the European Society of Cardiology 2026 https://www.medscape.com/viewarticle/mandrolas-preview-european-society-cardiology-2026-2026a1000tfi You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

In recent weeks, the collective bargaining agreement between the APL and PFA has been the topic on everyone's lips as negotiations have collapsed. But what is a CBA? What purpose does it serve? And where do the parties involved go from here with the start of the new A-League seasons drawing ever closer? Join Sam Lewis as we hear from Beau Busch, Dylan Holmes, and Steve Rosich about the current state of the CBA and where to from here. We acknowledge the traditional custodians of the land on which this podcast was recorded and produced on: the Wurundjeri Woi Wurrung people of the Kulin nation and the Gadigal people of the Eora nation. Related links A-League CBA explainer: What's going on between the APL and PFA? Follow The Far Post on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, and ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Check out ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠espn.com.au⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or download the ESPN App. Learn more about your ad choices. Visit podcastchoices.com/adchoices

This week we speak with Dr. Ted O'Leary, Co-Director of Adult Congenital Heart Disease Electrophysiology at Boston Children's Hospital about a recent publication he authored on the use of pulsed field ablation (PFA) for the transcatheter ablation management of complex atrial arrhythmias in ACHD patients. How does PFA work and what are some of the potential advantages and disadvantages of this novel ablation energy technology? What are the advantages of a variable loop catheter in this setting? Is PFA going to supplant radiofrequency current for standard "SVT" ablations one day? These are amongst the questions reviewed with Dr. O'Leary this week. DOI: 10.1161/CIRCEP.125.014619

Darragh and Phil are back for a new season of The Hard Truth and we're kicking off with a Hard Truth derby! But before that we need to catch up on a busy summer at Posh, despite what certain social media accounts my tell you!Peterborough United owner Darragh MacAnthony and Bradford City fan Philip Ideson give us the 'Hard Truths' and take a weekly look inside the football industry.On this episode:- The PFA take legal action against the EFL- Posh's summer transfers explained!- What can we expect from Bradford?- Has data made signing players harder?!- and much more!

The new EFL season is back with nine months of drama to come across the Championship, League One and League Two. Aaron Paul is joined by Andy Woodman, Luke Chambers and Lyle Taylor to preview all three divisions, looking at promotion contenders, relegated giants and, dark horses. West Ham and Wolves return to the second tier, Southampton and Middlesbrough all have their eyes on promotion. Bromley manager Andy Woodman discusses the club's historic first season in the third tier, while Leicester City and Sheffield Wednesday look to bounce back after relegation. Salford City manager Peter Cklamovski joins us to discuss his journey from Australia and Asia to English football, working with Ange Postecoglou and the pressure of taking charge of one of the division's promotion favourites.And don't forget to join the official 72+ EFL Fantasy League using the code 72EFLPOD. The 72+ Podcast now has a new home, just look for the 72+ Podcast feed on BBC Sounds or wherever you get your podcasts.00:00 Intro 02:10 Championship preview 03:05 West Ham 09:40 Wolves 13:50 Burnley 17:30 Southampton 22:40 Middlesbrough 25:40 Championship dark horses 31:30 League One and Bromley 36:10 PFA open legal proceedings over the EFL 37:10 Leicester City, Sheffield Wednesday and Oxford United 39:40 Salford City boss Peter Cklamovski 46:30 York City5Live commentaries this week: Wednesday 12th August: PSG v Aston Villa Sunday 16th August: Manchester City v Arsenal

Er det godt med flere fjæsinger i havet? Hvordan er det at leve med fibromyalgi? Hvorfor anbefaler PFA at vælge deres aktivt forvaltede fond? Dagens værter: Ole Brink og August Stenbroen.

Why do breakthrough medical technologies still fail to get adopted? In this episode of Med Tech Gurus, we sit down with David Neale, Co-Founder and CEO of Argá  MedTech, to explore what it really takes to bring a differentiated cardiac technology from concept to clinical adoption. Argá is advancing next-generation pulsed field ablation (PFA) for the treatment of atrial fibrillation, with early data showing 100% procedural success, strong safety, and high lesion durability. But as David explains, great clinical data alone isn't enough. Drawing on decades of experience in cardiac rhythm management, David shares why so many promising technologies fail—not because of engineering, but because they ignore physician workflow, hospital operations, and real-world usability. From designing a single, multi-configurable catheter platform to simplifying complex EP lab environments, Argá's strategy is built around one principle: innovation must fit the workflow to win adoption. We dive into lessons from first-in-human trials, the importance of disciplined execution, and why companies must design for three critical stakeholders: clinicians, operational teams, and administrators. David also shares practical insights on site selection, physician alignment, and how to move from strong data to real-world adoption. If you're interested in cardiac electrophysiology, pulsed field ablation, MedTech commercialization, clinical trials, or healthcare innovation, this episode delivers a powerful playbook for turning technology into adoption.

In this episode, Francis Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a novel study evaluating high‑voltage pulsed field ablation (hv‑PFA) for redo ventricular tachycardia ablation in patients with nonischemic cardiomyopathy. He highlights why VT ablation remains particularly challenging in this population, the rationale for using high‑voltage PFA to achieve deeper and more durable lesion formation, and the key findings from this early clinical experience. Dr. Marchlinski also comments on the encouraging efficacy signals, important safety considerations—including device and mapping system interactions—and what these results may mean for the future evolution of VT ablation strategies.

It's ev.news Briefly for Tuesday 04 August 2026, only today's headlines and just the facts in just 4 minutes if you haven't got time for the full show.Patreon supporters fund this show, get the episodes ad free, as soon as they're ready and are part of the ev.news Community. You can be like them by clicking here: https://www.patreon.com/evnewsEVS TAKE THE LEAD IN IRELAND'S NEW-CAR MARKET AS JULY HITS NEW RECORDBattery electric vehicles have become Ireland's top new-car fuel type, with July setting a record of 9,682 BEV registrations, up 97.67% year on year, taking the seven-month total to 29,840 units, a 61.06% rise on 2025. EVs held 26.1% of the market over that period, ahead of petrol-electric hybrids at 24.6%, petrol at 20.4%, PHEVs at 14.5% and diesel at 12.5%, with Nevo's Derek Reilly crediting lower running costs, newer technology and models priced between €20,000 and €30,000 for reaching the tipping point.VOLVO EX50 SET FOR US IN 2027Volvo will bring the EX50 compact electric crossover to US and Canadian showrooms in autumn 2027 at a price in the high $40,000s, replacing the EX40 as its entry-level US EV and filling a gap left when the EX30 and EX30 Cross Country exit after the 2026 model year. Production starts in spring 2027 at Volvo's $1.3 billion, 250,000-unit Kosice plant in Slovakia, using the SPA3 modular platform with an 800-volt system for faster charging, better efficiency and flexible battery and motor combinations.HYUNDAI AND KIA TOP 100,000 EUROPE EVSHyundai and Kia sold a combined 131,032 EVs in Europe in H1 2026, their first half-year above 100,000, putting them on course to beat 2025's full-year 183,912, as European BEV registrations rose 33.7% to over 1.24 million and took roughly 22% of the market. The Kia EV3 led with 27,121 units from around €36,000, while cheaper models filled out the range: the Hyundai Inster sold 16,594 units, the Kia EV2 launched in Germany in March at €26,600, and the EV4 added 14,502 units during its ramp-up.FRENCH BEV SHARE HITS 35% IN JULYBattery-electric cars took 35% of French new-car registrations in July 2026, with the PFA recording 44,378 BEVs from a market of 126,808 units that grew 9% year on year, roughly double the share of two years earlier. The rise coincided with Round 3 of France's social leasing scheme, reopened on July 16, which covers 29% of purchase price up to €6,500, rising to €9,000 for EEA-built vehicles and batteries plus €500 for an EEA motor, caps payments at €200 a month with no deposit, and has drawn offers such as the Citroën ë-C3 from €94 a month and Renault Twingo from €130.NORWAY HITS 97.6% EV SHARE IN JULYNorway registered 9,609 new passenger cars in July, up 0.5% year on year, of which 9,379 were battery-electric, a 97.6% share up from 96.9% in June, while Østfold reached 99.6% with 672 of 675 registrations. Used-market data followed suit, with private ownership transfers of used EVs up 8% in July against falls of 5.7% for diesel and 6.7% for petrol, and year-to-date used EV transfers up 43.2% to 103,892, now ahead of diesel overall.ALSO STARTS TM-B DELIVERIES AFTER DELAYAlso will deliver its first Launch Edition TM-B electric bikes this week through mid-September, ending a delay caused by an industry-wide surge in demand for raw materials and electronic components that left the bike short of key parts and stalled its manufacturing ramp-up. The TM-B uses a pedal-by-wire system in which pedalling spins a generator that communicates with the motor, with no mechanical link to the wheel, alongside a slick interface, over-the-air updates and a modular frame that accepts different seats and cargo racks.NISSAN SHOWS INTERSTAR-E ELECTRIC CAMPERVANNissan and German converter Eifelland will debut the Interstar-e Relax electric campervan at the Caravan Salon in Düsseldorf this month, using a Truma Eezy parking heater powered by vehicle-to-load from the 87 kWh traction battery, removing the need for a campsite hookup, diesel generator or engine idling. The donor van is rated at up to 255 miles (410 km) WLTP unladen, though the conversion's added weight will cut that materially, with 130 kW DC and 22 kW AC charging, a fixed bed, 90-litre fridge, induction hob, sink, wood trim and portable toilet, priced at €89,900 (about $102,000).CHUNG CHECKS IONIQ 3 TURKEY LAUNCHHyundai Motor Group Executive Chair Chung Eui-sun toured the group's Izmit plant near Istanbul on July 30 to check production readiness and quality control ahead of Ioniq 3 mass production in mid-August, also visiting Hyundai Mobis's Battery System Assembly plant and urging staff to make the car one of Europe's safest. The Ioniq 3 is Hyundai's first subcompact BEV built for Europe and the first EV made at Izmit, which has built combustion compacts since 1997, and it will roll out across Europe in H2 2026 as the first Hyundai there with the next-generation Pleos Connect infotainment system.FARIZON CUTS AUSTRALIAN SV VAN PRICESFarizon has cut prices by up to A$8,500 (US$5,570) across its SV electric van range in Australia, extending EV price competition into the light commercial segment, with revised pricing now starting at A$62,990 (US$41,260) before on-road costs for the SWB. The mid-size SV, with roughly 1t to 1.2t of payload, previously came in SWB low roof, LWB low roof and LWB high roof forms with an 83 kWh LFP battery, and has been joined by an SLWB high roof variant using a 106 kWh NMC pack.MASSACHUSETTS TARGETS EVS FOR GRID PAYMENTSMassachusetts plans to add electric cars to its virtual power plant under the next phase of ConnectedSolutions, paying owners to export power at peak times and extending vehicle-to-grid from school buses and commercial fleets into private driveways. The state's 150,000-plus EVs represent a notional 11.25GWh of storage at 75kWh each, though depth-of-discharge limits, charger power and everyday driving needs reduce that considerably; eligible models at launch are the Ford F-150 Lightning, Nissan Leaf, Kia EV9, Polestar 3 and Volvo EX90, paying $275 per average kilowatt delivered during summer events, or roughly $1,375 to $2,750 a season.QUEENSLAND E-BIKE CRACKDOWN NETS 991 TICKETSQueensland police issued 991 traffic infringement notices to e-bike riders in the first month of Operation Yankee Surety, which began on 1 July, averaging 32 a day, alongside 249 impounded illegal machines and 24 people charged with drink-riding. The crackdown rests on new laws allowing roadside seizure of non-compliant devices and breath-testing, with devices capable of exceeding 25km/h (15.5mph) banned outright and motors required to be restricted to that limit.ROMANIAN POWER CRUNCH STOPS FORD AND DACIAFord and Dacia have halted production at their Romanian factories through Aug. 19 after severe electricity shortages hit the country. Ford has suspended production of the Puma Gen E in Craiova, 230 km (134 miles) west of Bucharest.TESLA MODEL 3 POWERS HANDMADE MINI JETBOATYouTuber Tyler Fever spent three years stripping a 2021 Tesla Model 3 and fitting its drivetrain into a handbuilt aluminium mini jetboat hull, machining a custom output shaft to bypass the 9:1 reduction and couple the rotor directly to the jet pump, since the motor's roughly 18,000 rpm gave around 2,000 rpm against the 6,000–8,000 rpm impellers need. He used a standard-range pack for its smaller footprint, mounting four modules of about 150 lbs (68 kg) each vertically in laser-cut enclosures, and had to replace the factory BMS and motor controller with an Orion BMS and third-party inverter after they failed to communicate, with the series covering a successful lake run and later testing in Nashville.

Novas Tecnologias para Ablação de FA: O Papel do PFA by Cardiopapers

Box2Box, with Willem van Denderen & Will Hastie!The A-Leagues seasons look set for commencement without a playing labour agreement in place, a fortnight on from the PFA announcing CBA discussions with the APL had reached exhaustion. PFA chief-executive Beau Busch returns. Beau also discusses the week’s saddening news, with much-loved Captain Socceroo Paul Wade going public with his probable CTE diagnosis.Meanwhile on the pitch, the Australia Cup has been electric. Three Cupsets within 24 hours saw Preston Lions, Sydney United and Lions FC progress at the expense of A-League opposition; 10/Paramount’s Erik Paartalu discusses the big picture topics at play in Australia’s best sporting competition.Also on the agenda: Infantino complaint outside IOC’s remit, Klopp underway at Germany, Australia Cup & Championship maturation. Follow us on X: https://twitter.com/Box2BoxNTSLike us on Facebook: https://www.facebook.com/profile.php?id=100028871306243 Enjoy our written content: https://www.box2boxnts.com.au/See omnystudio.com/listener for privacy information.

Wales icon Jonny Williams is on the lookout for a new club after being released by Gillingham. To help his search, the 32-year-old has joined the PFA training camps alongside a host of other out-of-contract players. Could a move to Oxford United to be reunited with former Wales team-mates Aaron Ramsey and Chris Gunter be on the cards?And talking of international football, we couldn't let this opportunity pass without reminiscing about the magical summer of 2016, and how his camera skills upset Wayne Rooney. He also recalls the touching gift his international team mates bought him for his 18th birthday.One man not looking for a new club is Sam. He is very much retired, and reveals how his life now seems to be revolve around going to music festivals.

Pulsed Field Ablation for Atrial Fibrillation with Left Atrial Appendage Occlusion   Guest: Ammar Killu, M.B.B.S. Host: Anthony Kashou, M.D.   In this episode of Interviews with the Expert: ECG Making Waves, host Dr. Anthony Kashou is joined by Dr. Ammar Killu to discuss the evolving role of combining pulsed field ablation (PFA) with left atrial appendage occlusion (LAAO) for patients with atrial fibrillation. Together, they explore the rationale for a combined approach, the potential advantages of PFA over conventional thermal ablation, and key procedural considerations for performing both interventions safely and effectively in a single session.   Topics Discussed: Why consider combining pulsed field ablation and left atrial appendage occlusion in the same AF patient? What does PFA add compared with conventional thermal ablation when planning a combined ablation–LAAO strategy? What are the procedural caveats when PFA and LAAO are done concomitantly?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode.   Podcast episode transcript found here.   Recorded on: 26-June-2026  

Box2Box, with Rob Gilbert and Willem van DenderenThe Australia Cup returns this week, with nine debutants among the 32 sides set to contest the national stage. Lachie Flannigan (10/Paramount+) will be behind the mic as Rochdale Rovers meet Southern Districts Raiders on Tuesday evening, and throughout the competition; he joins Box2Box for the first time to preview its commencement.Then to the never-ending political and ethical machinations of FIFA and its tournaments. What impact has the White House’s intervention had on Gianni Infantino’s presidency stronghold? What of its increasingly fawning adulation of its superstars? The Times Chief Sports Reporter Martyn Ziegler returns to run the moral compass over a madcap administration in full flow.Also on the agenda: Bellingham, Tuchel, Embolo & Vozinha’s sea slug, and CBA negotiations break down between the APL & PFA.Follow us on X: https://twitter.com/Box2BoxNTSLike us on Facebook: https://www.facebook.com/profile.php?id=100028871306243 Enjoy our written content: https://www.box2boxnts.com.au/See omnystudio.com/listener for privacy information.

Sommeren står for døren, men verden buldrer videre. Hvad kan få direktøren for Danmarks største pensionsselskab op ad liggestolen? Vi giver dig en 'holde øje med'-guide til ferien. Og apropos ferie, så er det her afsnit af Sorte tal optaget med fødderne i Hollandsk søvand, hvor vi også vender forsvarsindustrien, Sallings føretrøje og Novo Nordisks festivalsommer. Vært: Ulrik Rosenkvist Schultz, Fast gæst: Sune Aagaard. Medvirkende: Ole Krogh Petersen, direktør for PFA.

Investorerne kigger mod AI- og chipaktier - hvor det kun er gået en vej de seneste år. Sniger der sig en gang FOMO ind, hvis man ikke er med? Er det for sent at hoppe med på vognen? Og er vi der, hvor lidt for mange måske er med til festen? Vi slår også et smut forbi Novo Nordisk. Måske venter der en god nyhed rundt om hjørnet? Per Hansen mener i hvert fald, at tallene taler for en opjustering. Det er en sammenblanding af pillesalg og nye markeder. Vi får Per til at uddybe. Vært: Ulrik Rosenkvist Schultz. Fast gæst: Sune Aagaard. Medvirkende: Per Hansen, investeringsøkonom hos Nordnet og Tine Choi Danielsen, chefstrateg hos PFA.

Naptown Blues Fancast covers the full swing of emotions that is USL2 football. Wednesday brought East Coast semifinalists Lionsbridge to NMCMS, and the result — a 2-0 defeat — was hard to argue with. The Blues controlled possession and put up 6 shots, but none of them truly tested the keeper, and a quickly taken short corner early in the second half effectively ended the contest. Sam and Hiram don't sugarcoat it. We also get to know a couple of new faces: Brazilian newcomer Enzo DeAlmedia and substitute Ollie Snowden, one of the few bright spots on the night. Saturday was a different story entirely. PFA came to town and the Blues were ready — scoring inside three minutes through Rich Monath, surviving a lightning delay, and then absolutely running riot for a 7-0 final. Penalty goal from captain Tyler Gabara. A cheeky chip from Roshawn Panton. Two rockets from substitute Caleb Pritchett. And a hat trick to close it out for Rich Monath. Crabtown Blues showed up loud for a wings-and-hair-metal tailgate and never let up. Post-match audio from Gabara, Pritchett, and Monath included. Sam also previews the playoff picture and the road ahead — Wednesday at Loudon, then Christos the following Monday. For tickets and schedules: annapolisblues.com Premier League coverage DU Football Show.

Based on long-term results, “the effectiveness of that nanosecond pulse electric field begins to look as if it is a step function ahead of first generation PFA,” Pulse Biosciences CEO Paul LaViolette says, referring to the next stage of pulsed-field ablation innovation. In this Vanguards of Healthcare episode, LaViolette sits down with BI analyst Matt Henriksson for an in-depth interview about the potential benefits of nanosecond ablation technology to treat atrial fibrillation, which combines an ultrashort pulse duration with a high amplitude of voltage. LaViolette also discusses the commercial strategy behind the launch of its NANOPULSE-AF IDE pivotal study, following promising first-in-human trial results.See omnystudio.com/listener for privacy information.

(0:08:00): PFA server had massive crash, prior radio show was lost, so what now?.... (0:14:18): Major update related to The Lodge raid and shutdown.... (0:39:01): Maurice Hawkins appears on Pokernews podcast to argue with hosts about his bad debts and scamming allegations.... (1:36:15): Dylan Lynde reveals nosebleed stakes tournament player David Peters revealed to be broke and owing him $23k.... (2:12:49): Charlie Carrel and Owen "PR0DIGY" Messere in private game dispute where both accuse each other of unethical behavior.... (3:27:24): CoinPoker in more controversy as major affiliate accuses them of cheating him, plus their terms of service seems to prohibit US and UK players from the platform.... (3:39:32): All of Primm to close down on or before July 4.... (3:49:24): Vegas Megabucks tipping controversy goes viral when major X account shares VitalVegas' post on the matter.

Anna Thygesen er kommunikationsrådgiver, foredragsholder og en af Danmarks mest erfarne kriseeksperter I dagens afsnit snakker vi om kriser. De aktuelle kriser i verden, men også hvordan man helt konkret håndterer dem som offentlig person eller virksomhed. Vi kommer blandt andet forbi Sisse Sejr-sagen set fra et kommunikationsperspektiv, Trump, Iran-konflikten, Epstein-filerne og ikke mindst PFA-sagen, hvor Anna selv stod midt i det hele. Derudover snakker vi om hvordan man egentlig bør kommunikere i en krise, hvad der virker og hvad der ikke gør, og hvordan vi i 2026 ser en udvikling hvor brands gerne vil være personlige, mens personer i stigende grad bliver til brands. Gå fornøjelse, Christian. Vil du høre resten? Så find hele episoden eksklusivt på Podimo: http://podimo.dk/christian Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Time to quadruple therapy, the disappointing AVANT GUARD trial, PFA risks, the TREAT-PVC trial, and NSTEMI care in the frail elderly are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Time to Quadruple Therapy in HFrEF Time to Quadruple Therapy After Diagnosis of HFrEF https://jamanetwork.com/journals/jamacardiology/fullarticle/2846899 II AVANT GUARD PFA Bests Meds as First-Line Treatment for Persistent AF in Randomized Trial https://www.medscape.com/viewarticle/pulsed-field-ablation-bests-meds-first-line-treatment-2026a1000dsm Pulsed Field Ablation of AF Disappoints in Setup for Success: AVANT GUARD https://www.medscape.com/viewarticle/pulsed-field-ablation-af-disappoints-setup-success-avant-2026a1000ddt AVANT GUARD Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2600929 Persistent AF: Meta-analysis of Invasive Strategies 10.1016/j.ijcard.2018.11.127 External Link III Speaking of Scary News on PFA – The TIFFANY Study Abstract - The TIFFANY Study https://www.heartrhythmjournal.com/article/S1547-5271(26)01747-9/fulltext Delayed Myocardial Ischemia and Malignant Arrhythmias After PFA https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.125.077983 Alberto Alfie Comment https://x.com/ALFIEEP1/status/2050029151315189774?s=20 IV TREAT PVC Trial TREAT-PVC Trial https://doi.org/10.1016/j.jacep.2026.01.011 TREAT-AF Study 2020 https://doi.org/10.1016/j.jacep.2019.11.008 V NSTEMI In Frail Older Patients SENIOR-RITA Trial https://www.nejm.org/doi/10.1056/NEJMoa2407791 Subanalysis of Senior RITA Trial https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2847995 Timing of Invasive Strategy in Patients With Non-ST-Elevation Acute Coronary Syndrome -- Meta-analysis https://doi.org/10.1016/S0140-6736(17)31490-3 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

This is a big weekend for the equine industry. Another big show - in Minnesota. Jill Welke talks with the organizers of the show and entertainment at the MN Horse Expo.] Rainfall reports are spotty this morning around Wisconsin. Stu Muck says western Wisconsin suffered the brunt of the heavy rainfall. Drier weather for most of the weekend with rain back in the forecast on Monday. The legislative session is in the rear view mirror for agriculture right now. Stephanie Hoff gets a quick recap on some highline items from Jason Mungniani, government affairs specialist with the WI Farm Bureau Federation. Aside from noting "wins" on things like PFA's protection and road weight adjustments, Mungniani also says they've started a campaign to engage with not only existing lawmakers, but potential candidates. Dubbed "Engage with Ag", it's made up of a consortium of bipartisan groups and associations from Wisconsin agriculture, offering farm visits and personal education about today's farms and agriculture. Award winning author James Patterson will keynote graduation ceremonies for UW Madison grads. His wife, Sue, is an alumnae of the UW. In honor of the high profile couple, Babcock Dairy has created Patterson #1 Triple Chocolate. A decadent new flavor unveiled this week. Pam Jahnke explains the ingredients and availability. Speaking of graduation - how's the job market. With agriculture facing some difficult economics, what does the job market look like? Ben Jarboe gets some perspective from Mia Dauphin. She's a double major in agribusiness and dairy science. She's actually graduating early in a blazing 3 years. She's secured a job in the feed industry, but suggests current students seek out internships and real world experiences before the exit campus.See omnystudio.com/listener for privacy information.

Shareholder Advocacy in 2026: A Season Defined by Upheaval and Resilience *A deeper look at the key themes and proposals in the Proxy Preview 2026 report by As You Sow and Proxy Impact* The 2026 proxy season is arriving amid one of the most turbulent regulatory environments shareholder advocates have faced in decades. Actions by the Securities and Exchange Commission (SEC) under Chair Paul Atkins have introduced a series of new barriers to shareholder participation — limiting who can file resolutions, restricting exempt solicitations on EDGAR, and signaling a broader retreat from the corporate disclosure requirements that have defined the modern era of investor oversight. Filing thresholds have been quietly tightened. The procedural goalposts have moved. And the agency that once served as a neutral referee on what does and does not belong on a proxy ballot has, in practice, stepped off the field. And yet, shareholders are not retreating. As Proxy Preview publisher Andrew Behar puts it, they are “standing shoulder to shoulder” — the early warning system that corporations have long relied on, whether they admit it or not. The proposals filed this year are, if anything, more ambitious than in seasons past. Investors are not waiting to see how the regulatory landscape settles. They are filing, litigating, and engaging on the assumption that the right to ask questions about material risk is theirs to exercise regardless of who chairs the SEC. This year’s Proxy Preview, produced by As You Sow and Proxy Impact, offers a sweeping look at the environmental, social, and governance (ESG) proposals headed to shareholder votes in 2026. The themes range from the data center buildout reshaping America’s electricity grid, to the legal liabilities mounting against Big Tech, to the quiet but consequential question of who gets to decide what counts as “proper business” at an annual meeting. Here’s what investors need to know. The Political and Legal Backdrop The story of the 2026 season cannot be told without first addressing what happened to the SEC’s no-action process. Historically, when a company wanted to exclude a shareholder proposal from its proxy statement, it would file a no-action request with the SEC, which would review the proposal on its merits and issue guidance. That process — imperfect but functional — was effectively suspended this year, triggered in part by a prolonged government shutdown that left the agency without the bandwidth to render decisions. The result was a free-for-all. Companies, sensing an opening, filed notices of intent to exclude proposals on a range of novel theories. The most aggressive of these was the so-called “Delaware Proper Business” argument, which holds that advisory shareholder proposals — the non-binding resolutions that have been the backbone of shareholder advocacy for decades — are not “proper business” for an annual meeting under Delaware corporate law. If accepted, that theory would effectively wipe out the entire category. Shareholders pushed back, hard. Lawsuits were filed against AT&T, Axon, Chubb, BJ’s Wholesale, and PepsiCo. AT&T and Pepsi settled quickly, restoring the proposals to their proxies. At Axon, a federal court ordered the parties to explore a negotiated resolution rather than rule on the merits — a signal that judges are skeptical of the broad exclusion theories companies have been advancing. The Chubb and BJ’s cases remain in active litigation as of this writing. Meanwhile, in a parallel front, a federal court struck down Texas Senate Bill 13 — the state’s anti-ESG law that restricted public pension funds from doing business with financial firms deemed to “boycott” fossil fuel companies — as unconstitutionally overbroad and vague. It is the first federal court decision to invalidate this type of statute, and it sets up a potential precedent that could unwind similar laws in roughly a dozen other states. The pattern, taken together, is clear. Where companies and state legislatures have tried to use procedural and legal tools to silence shareholder voice, the courts have so far been unwilling to go along. Climate: Data Centers, Stranded Assets, and Insurance If there is one new climate story dominating the 2026 season, it is the AI buildout. The numbers are striking. In 2025, the number of proposed fossil gas plants in the U.S. nearly tripled, driven almost entirely by soaring electricity demand from new data centers. Utilities that had been quietly retiring coal and gas capacity are now reversing course, citing grid commitments to hyperscale tech customers as the rationale. Investors are responding. Proposals at Amazon, Meta, and Alphabet request disclosure on how the companies’ growing data center operations are compatible with their previously announced climate commitments — many of which include net-zero pledges that look increasingly difficult to reconcile with multi-gigawatt computing expansion. Similar proposals target the utility side of the equation, including Dominion Energy and Southern Company, both of which are major suppliers to data center hubs in Virginia and Georgia. At the same time, the U.S. is in the middle of a climate-driven insurance crisis that is starting to attract serious investor attention. Insured natural-catastrophe losses reached $117 billion in 2024 — more than double the ten-year average. Homeowners insurance premiums rose 24% between 2021 and 2024, and entire ZIP codes in California, Florida, and Louisiana have effectively become uninsurable on the private market. As You Sow has filed a novel “subrogation” proposal at Chubb, asking the insurer to explore using subrogation claims against large emitters to offset climate-related losses. The legal theory borrows from the playbook used against tobacco and opioid manufacturers: if you can identify the parties whose conduct caused the harm, you can pursue them for the cost of paying out claims. Climate transition planning remains a critical investor concern more broadly. Proposals at Harley-Davidson and Verizon push these companies — both of which have ambitious net-zero commitments but published no sustainability reports in 2025 — to develop credible, stand-alone transition plans. The implicit argument is that a target without a plan is not a commitment; it is a press release. Biodiversity: Horseshoe Crabs and Avocado Supply Chains Two of the most distinctive proposals this season concern biodiversity, and both illustrate how shareholder advocacy can move industries that regulators have not. The pharmaceutical industry’s dependence on horseshoe crab blood for drug safety testing is under fresh scrutiny. The compound extracted from the crabs — limulus amebocyte lysate, or LAL — is used to detect bacterial endotoxins in injectable drugs and implantable medical devices. Each year, roughly 1.1 million horseshoe crabs are harvested and bled, with the industry historically claiming low post-bleeding mortality. Independent research suggests the actual mortality rate is closer to 30%, with knock-on effects for shorebirds and other species that depend on horseshoe crab eggs as a food source. Synthetic alternatives — recombinant Factor C, or rFC — have been commercially available since 2003 and are used routinely by Eli Lilly and others. The U.S. Pharmacopeia, the standards body that governs pharmaceutical testing in the U.S., updated its standards in November 2024 to place rFC on equal regulatory footing with the animal-derived test. That removes the last meaningful technical barrier to transition. Proposals at Abbott and Merck request disclosure about transition timelines. The avocado story is, in some ways, a more hopeful one — a case study in what sustained shareholder engagement can accomplish over time. Mexican avocado production has long been linked to illegal deforestation, with growers clearing protected forest in Michoacán to plant new orchards. As You Sow’s decade-long push for Pro Forest Avocado (PFA) certification — a satellite-based system that monitors orchards in real time for evidence of land-use change — has transformed the supply chain. As of March 2026, over 60 Mexican avocado packers are PFA-certified, and major U.S. retailers including Costco, Walmart, and Kroger have committed to sourcing from certified suppliers. The notable holdout is Albertsons, which has not responded to repeated engagement requests and is the focus of a 2026 proposal. Social: Human Rights, Surveillance, and Child Safety Big Tech is facing what Michael Passoff of Proxy Impact calls its “Big Tobacco moment” — the period when accumulating evidence of harm crosses the threshold from controversial to legally actionable, and the financial consequences begin to compound. The numbers from the past twelve months are difficult to dismiss. In March 2026, Meta was found guilty of violating New Mexico’s consumer protection law and penalized $375 million for its handling of minors on Instagram. Separately, a California court found Meta and Google guilty of creating addictive platform designs that harm young users’ mental health, in a verdict that is likely to be the template for similar cases in other states. Meta’s stock dropped 8% following the verdicts, suggesting the market is finally beginning to price in legal risk that shareholders have been flagging for years. On surveillance, investors at Alphabet/Google and Home Depot are pressing for oversight of customer and user data. The specific concerns are concrete. Home Depot cameras installed in parking lots have, according to public reporting, enabled ICE raids targeting day laborers. Google was hit with a $425.7 million verdict for tracking 98 million users after they had explicitly turned location tracking off. In both cases, the proposals ask not for the companies to change their business models, but for the boards to take responsibility for the data practices their products create. New this year, and likely to attract significant attention: a proposal at Palantir asking the company to conduct a Human Rights Impact Assessment related to its products and services. The proposal follows reports that Palantir’s software is being used by ICE to track and target migrants, including in operations that have separated families and detained individuals without prior criminal records. Palantir has historically resisted human rights disclosure on the grounds that its government contracts are confidential; the proposal tests whether shareholders can compel disclosure of the broader policy framework even when specific contract terms remain under seal. Political Spending and Lobbying Corporate political spending is under heightened scrutiny as the 2026 midterm elections approach. The Center for Political Accountability (CPA), which has been the leading shareholder voice on this issue for two decades, filed disclosure proposals at 29 companies this proxy season. The proposals ask for disclosure of corporate political contributions, including those made to trade associations and other intermediaries that often serve as a workaround for direct disclosure requirements. What is striking is the response. Despite the SEC’s effective invitation to exclude most shareholder proposals this year, only 7 of the 29 companies chose to do so. The other 22 let the proposals proceed to a vote — a tacit acknowledgment that the political risk of being seen to suppress shareholder voice on political spending now outweighs the cost of disclosure. The CPA proposal averaged 41.4% support over 13 votes in 2025, including five majority votes, putting it well above the threshold at which boards typically engage seriously with proponents. The lobbying disclosure campaign also continues, though with a revised proposal structure following a 2025 setback when the SEC sided with Air Products and Chemicals on a technical exclusion argument. The new, streamlined proposal — focused on direct federal and state lobbying amounts and third-party recipients — is being filed at 7 companies including Goldman Sachs, J.P. Morgan Chase, and Morgan Stanley. The narrower scope is designed to be procedurally bulletproof, leaving the substantive question — should a public company tell its owners how much it spends to influence legislation — on the table for shareholders to answer. Governance: Board Accountability and Executive Pay Several governance proposals this season cut to the question of what boards are actually responsible for. Shareholders are requesting that boards provide specific oversight of AI development, climate change, Indigenous peoples’ rights, and data protection — areas where the gap between executive decision-making and board supervision has become particularly wide. A notable Vote No campaign: NYC Pension Funds, the third-largest public pension system in the country, urged Starbucks shareholders to vote against the re-election of two directors, citing over 700 unfair labor practice charges, 60 adverse administrative law decisions, and the quiet disbanding of a labor relations oversight committee that had been formed in response to earlier shareholder pressure. The campaign is significant not only for its scale but for the specificity of its case: this is not a general grievance about management, but a documented record of regulatory findings the directors are charged with overseeing. A new executive compensation proposal at Meta links CEO and executive bonuses to improvements in child safety metrics — a direct response to the company’s mounting legal liability over platform harms to minors. The proposal is structurally interesting because it does not ask the company to take any specific action; it asks only that the compensation committee tie pay to outcomes the company itself has acknowledged as material. If child safety is, as Meta has repeatedly stated in public, a top priority, then linking executive pay to it should be uncontroversial. The vote will reveal whether the board agrees. The Bottom Line The 2026 proxy season is, more than anything, a test of whether shareholders can maintain their voice in corporate governance amid a hostile regulatory environment. The evidence so far is encouraging. When companies have tried to unilaterally exclude proposals, they have largely faced legal challenges and backed down. When state legislatures have tried to penalize ESG-aligned investing, federal courts have intervened. When boards have tried to ignore mounting legal liability, the markets have begun to do the disciplining themselves. As shareholder advocate Nell Minow writes, the likely cost-benefit analysis from executives “who thought they could keep the proposals from going to a shareholder vote was not clear to them until they faced the very real possibility that a court ruling on the legitimacy of the challenged proposal would be a much bigger problem.” In other words: the bet that the SEC’s retreat would translate into a free hand for management has not paid off. The deterrents have simply moved from the regulator to the courts and the proxy ballot itself. Fundamental ownership rights — the right to ask questions about material risks — are not granted by regulators. They are inherent to ownership itself. The 2026 season is shaping up to be the year that principle gets tested, and so far, it is holding. — *Sources: Proxy Preview 2026, published by As You Sow and Proxy Impact. Full report available at [proxypreview.org](https://www.proxypreview.org/).*

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Tam McManus is now in serious pain, as he believes Hearts are now looking odds-on to win the Scottish Premiership. Have Rangers blown it? Can Celtic sneak in to win the league? The PFA player of the year and young player of the year are discussed on the show.

PCSK9 inhibitors in high-risk diabetes without ASCVD, the CAAN-AF trial, conduction system pacing vs biventricular pacing, PFA and stroke, and therapeutic fashion infects expert consensus are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I VESALIUS-CV  VESALIUS-CV Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2514428 JAMA Substudy https://jamanetwork.com/journals/jama/fullarticle/2847162 II How Best to Maximize CRT Benefit in Patients with AF CAAN-AF Trial https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehag206/8654625?searchresult=1 Role of AV Node Ablation: Meta-analysis of Observational Studies https://www.jacc.org/doi/10.1016/j.jacc.2011.10.891 III Stroke Rates in PFA vs Thermal Ablation Comparative Safety of RF versus PFA for AF in a High-Volume US Medical Center https://esc365.escardio.org/Ehra-congress/sessions/18281 IV Five New CSP Studies Presented and Published HeartSync-LBBP Trial https://jamanetwork.com/journals/jamacardiology/fullarticle/2845803 PhysioSync-HF Trial https://jamanetwork.com/journals/jamacardiology/fullarticle/2845802 LEFT-BUNDLE-CRT Trial https://doi.org/10.1093/eurheartj/ehag225 Long-Term Follow-up of His-Alternative I Trial https://www.jacc.org/doi/10.1016/j.jacep.2026.02.016 LECART Trial https://esc365.escardio.org/Ehra-congress/sessions/17140 V New EP Training Document Published Advanced Training Statement on Clinical Cardiac Electrophysiology  https://www.jacc.org/doi/10.1016/j.jacc.2026.01.074 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

In this podcast, Francis Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a novel pulsed field ablation–based endocardial strategy for ventricular tachycardia in patients with arrhythmogenic right ventricular cardiomyopathy. The paper presents an early consecutive experience demonstrating the feasibility, acute effectiveness, and safety of PFA for VT without the need for epicardial access. Dr. Marchlinski highlights the clinical implications of this approach and how tissue-selective, nonthermal energy may expand treatment options for this challenging patient population.

Gordon Duncan, Hugh Keevins and Scott Allan take your calls ahead of the Scottish cup semi-finals this weekend, and debate the PFA team of the year.Plus, there's Beat the Pundit and the Full Time Teaser.

Dr. Chris Rhodes explains what fasting is actually doing in the body, where the benefits begin, and why shorter fasting windows may not deliver what many people expect. He walks us through the science behind fasting mimetics, including how his team studied a 36-hour fast and built a supplement around the molecules that arise during it. You come away with a clearer way to think about hunger control, food noise, metabolic health, and the tradeoffs between fasting, appetite-suppressing drugs, and everyday eating. He also offers a sharp take on saturated fat hype and makes the case for a more personal, evidence-based future in nutrition.Big Announcement: The Super Age Games are here! Join us November 7th in NYC for an entirely new longevity competition.Special Thanks to Our SponsorsLMNT Electrolytes: Our #1 electrolytes for optimal hydration, and their new 12oz sparkling cans are officially for sale online! Get a free Sample Pack of LMNT's most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.Fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and Fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.Our Place: The top cookware brand for beautiful, non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com. Key Moments"What most people do not realize is that they are often not getting the benefits of fasting that they think that they are getting."“From a biological perspective, it takes around 24 hours without food in order to actually activate that metabolic switch where you're going from, you know, fed metabolism, glucose metabolism, over into ketone metabolism and fasting metabolism.”"Let's find patterns that work specifically for you."Connect with Chris RhodesWebsite: mimiohealth.comLinkedIn: linkedin.com/in/chrishrhodesConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

You can only go so far when managing yourself in unprecedented times, but managing your financial future requires keeping both an eye on the news and your mind free from panic. In this episode of Dollars to Dreams, Tyler Hafford and PFA's Chief Investment Officer, Sam Chaplin, discuss the ramifications of the U.S. and Israeli conflict with Iran, and what this means for stocks, for oil, and for everyone who's trying to stay afloat through this.  YOU'LL LEARN: How much war costs consumers in the long run. How the market reacts to big news, and how it responds in the aftermath. The pillar of the oil trade, and how the world might operate in the face of a shortage. Produced by Sutherland Weston. Contact us at https://sutherlandweston.com/  

Looking for quick strategies for building sustainable fitness habits? This week, we revisit a conversation with former firefighter-turned-osteopath and author David Vaux, where he shares wisdom from a lifetime of grit and strength. We all know that muscle mass will greatly improve our healthspan, but the perfect way to build and maintain that strength can be elusive. Get the inside scoop on balancing physical challenges with proper recovery. Find key guidance on staying fit and resilient, no matter your age.Thanks to our sponsors:Timeline Nutrition — our favorite supplement for cell support and mitochondrial function. Listeners receive 20% off your first order of Mitopure with code AGEIST at TimelineNutrition.com/ageist.LMNT Electrolytes – Our #1 electrolytes for optimal hydration, and their new 12oz sparkling cans are officially for sale online! Get a free Sample Pack of LMNT's most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.Our Place – our favorite cookware brand for non-toxic, PFA-free pots and pans. Use code AGEIST for 10% off at fromourplace.comKey Quotes“Fast-twitch fibers are the currency of healthy aging.”“It's not about becoming injured or burnt out; it's about consistency.”“Strength training is like brushing your teeth: something you just do.”Connect with David VauxBook Stronger: How to Build Strength, The Secret to a Longer, Healthier LifeLinkedIn  TwitterFull TranscriptConnect with AGEISTNewsletterInstagramWebsiteSay hi to the AGEIST team!

Filmmaker David Donnelly joins us to discuss his new documentary Forever Young, an exploration of the rapidly advancing science of longevity. What began as a skeptical investigation into whether the hype around anti-aging breakthroughs was real ultimately revealed a growing body of research focused on extending healthspan and preventing disease. We examine what the science supports today, from the role of prevention and lifestyle to emerging therapies now entering human trials. Along the way, David raises larger questions about purpose, social connection, and how society must adapt as people begin to live longer and healthier lives. Special Thanks to Our SponsorsOur Place: The top cookware brand for beautiful, non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com. Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.Fatty15 – C15 is the first essential fatty acid to be discovered In 90 years. Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter code: AGEIST at checkout.Key Moments"Normal is not necessarily healthy.""The number one indicator for how long you live in the United States right now is your zip code.""We are living through a real revolution when it comes to longevity."Connect with David DonnellyWatch the Film – https://www.foreveryoung.film/?via=dSubstack — https://foreveryoungfilm.substack.com/Instagram — https://www.instagram.com/foreveryoungdocX — https://x.com/theagingdocFB — https://www.facebook.com/people/Forever-Young-Film/61572955294447/YT — https://www.youtube.com/@ForeverYoung-FilmConnect with AGEISTNewsletterInstagramWebsiteLinkedInSay hi to the AGEIST team!

Treatment for atrial fibrillation (A-fib) is becoming safer and more efficient with the addition of pulsed field ablation (PFA). Cardiac electrophysiologist William Maddox, M.D., explains how PFA targets cardiac tissue while sparing nearby structures and how it can be combined with radiofrequency ablation when needed.

A superb note on CPR and DNR orders, patients' vs doctors' preferences for statins, more on GLP-1s, another LAAC story, and some closing cautionary notes on PFA are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Listener Feedback Addressing Inadequate Documentation of Unilateral DNR https://jamanetwork.com/journals/jama/fullarticle/2829203 Video: Can We Talk About CPR? https://www.youtube.com/watch?v=yTCRfY3ETvI Personal Reminiscences of CPR's Origin https://www.ajconline.org/article/S0002-9149(03)00977-9/pdf II Public Preferences for Statin Therapy Measuring Public Preferences for Statin Therapy https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2844660 III GLP-1 RA News ACHIEVE Trial https://doi.org/10.1016/S0140-6736(26)00202-3 IV New Trial in GLP-1 for Patients with AF Seminal-AF Trial https://clinicaltrials.gov/study/NCT06499857 V Relationship between Spontaneous Echo Contrast and LAAC Outcomes OCEAN-LAAC Trial https://doi.org/10.1016/j.jacep.2025.09.028 News Release on Upcoming LAAOS-4 trial  https://www.phri.ca/watchman/ Reading the "Smoke" -- Editorial on OCEAN-LAAC https://www.jacc.org/doi/10.1016/j.jacep.2025.10.029 VI Concluding Remarks on My Talk at Western AF Delayed Myocardial Ischemia and Malignant Arrhythmias After PFA https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.077983 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Nano Banana 2 is Google's best image model yet and it just dropped. It's cheaper, it's smarter, and it removed an Adidas logo from a banana in a tracksuit on the first try. But we have notes. The Door Brothers and Logan Paul made a 15-minute AI movie with Seedance 2.0 that looks like a direct-to-video action film…KIND OF. Meanwhile Seedance 2.0 is now live in CapCut, Anthropic is in a standoff with the Secretary of War over a $200M defense contract, and a sketchy music site called Sonato is generating perfect James Brown and Nirvana tracks from text prompts.  Using that, Kevin vibe coded a custom AI Spotify mash-up that looks like an iPod. During the show. While apologizing. Plus we built a whole new AI For Humans website from scratch with Claude Code, the stock market crashed because of an AI memo, and Deep Seek V4 might drop any minute now. Totally normal week. KEVIN OWES US ALL AN APOLOGY AND HE KNOWS IT. #ai #ainews #openai Come to our Discord: https://discord.gg/muD2TYgC8f Join our Patreon: https://www.patreon.com/AIForHumansShow AI For Humans Newsletter: https://aiforhumans.beehiiv.com/ Follow us for more on X @AIForHumansShow Join our TikTok @aiforhumansshow To book us for speaking, please visit our website: https://www.aiforhumans.show/   // Show Links // Nano Banana 2 Launch https://x.com/GoogleDeepMind/status/2027051577899380991?s=20 https://blog.google/innovation-and-ai/technology/ai/nano-banana-2/ Nano Banana 2 Window App:  https://x.com/sundarpichai/status/2027057726170509724?s=20 Complex Imagery:  https://x.com/emollick/status/2027051701258109306?s=20 Precise Editing of Adidas Tracksuit:  https://gemini.google.com/share/4d9ab1243d40 Failed at my Periodic Table test: https: //x.com/gavinpurcell/status/2027058092824027238?s=20 Dor Brothers / Logan Paul 15 Minute Movie https://x.com/thedorbrothers/status/2026733954942775433?s=20 Creator of Entourage Responds LOL https://x.com/mrdougellin/status/2026801159282057666?s=20 Seedance 2.0 Updates Now In CapCut? https://x.com/charliebcurran/status/2026713011805946301?s=20 Lil' Hot Dog Video I Made In CapCut https://x.com/gavinpurcell/status/2026751216139542733?s=20 Weights Leaked? Likely Fake https://x.com/taker_of_whizz/status/2026749425851253095?s=20 Tom Cruise/Brad Pitt Creator Second Video:  https://x.com/RuairiRobinson/status/2026164263547793787?s=20 My Chicken Run 90 Min Example:  https://x.com/gavinpurcell/status/2025260426519609557?s=20 Energym by AI Candy https://www.aicandy.be/giorgio-1 Citrini Piece Tanks Stock Market (Claude Code) https://www.citriniresearch.com/p/2028gic https://www.nytimes.com/2026/02/25/business/citrini-ai-stock-market.html?unlocked_article_code=1.PFA.WBh9.KPcM171X5cU2&smid=url-share Anthropic Use Growing Much Faster Than OpenAI or Gemini https://x.com/deedydas/status/2027057965862432843?s=20 New Claude Co-Work Plugins For Many Disciplines https://x.com/claudeai/status/2026305186671608315?s=20 Remote Control For Claude Code / Cowork https://x.com/noahzweben/status/2026371260805271615?s=20 Scheduled Tasks in Cowork https://x.com/claudeai/status/2026720870631354429?s=20 Fighting Vs The Pentagon Re AI Safety In War*** https://www.axios.com/2026/02/24/anthropic-pentagon-claude-hegseth-dario Theo Replicates & OpenSources Frame IO https://x.com/theo/status/2026794317197849001?s=20 Sonauto: AI Music With WAY Too Many Actual Voices https://sonauto.a Theoretically Media on Sonauto:  https://youtu.be/fK886jyF9Hw?si=DMbV4vikeD6y_jeP DeepSeek v4 Trained on Blackwell Chips https://x.com/niubi/status/2026111153617727843?s=20 New AI For Humans Website! https://www.aiforhumans.show/  

Judi Wineland, world traveler and founder of Adventure Women explains how a lifetime of extreme travel shaped her idea of “aliveness,” and why the right trip can change your relationship to your body, your confidence, and your attention. She breaks down what happens when women travel together without the labels and expectations they carry at home, and why that can unlock sharper honesty, better friendships, and a renewed sense of play. You'll hear how awe, discomfort, and laughter become practical tools for building resilience, whether you're walking an old pilgrimage route in Japan or feeling tiny on the Serengeti. If you want a clear-eyed take on how travel can support wellness, fitness, and personal momentum at any age, this episode is a blueprint. Special Thanks to Our SponsorsFatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and Fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.Puori Grass Fed Whey Protein: 21g of whey protein per serving from grass-fed cows, with 6g BCAAs and 2.4g leucine, free from hormones, GMOs, and pesticides. Use code AGEIST at puori.com/AGEIST to get 32% off Puori Grass-fed Whey Protein when you start a subscription.Our Place: The top cookware brand for beautiful, non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com.Key Moments“It's not just about travel. And we had these wonderful conversations and we laugh a lot because we also do these trips and go out and challenge ourselves a bit.”“You have to be open to it. You have to be ready and vulnerable, ready for vulnerabilities.”“Well, I would want to maybe challenge the fact that not all of us, not all people are as brave. You have to be a little bit vulnerable to allow yourself to be open, to allow others in, to allow the earth in, to allow the air in, to allow things to affect you.”Connect with JudiSuper Age x Adventure Women ImmersionsLinkedInInstagramAdventureWomen InstagramConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

Join Digital Education Committee member and podcast host Deep Chandh Raja, MBBS, MD, PhD, along with this week's guest contributors, Senthil Thambidorai, MD, FHRS  and Lee Karl Thien, MD, CCDS for this week's episode. This real-world registry study evaluated the safety, feasibility, and mid-term outcomes of pulsed field ablation (PFA) for cavotricuspid isthmus (CTI)–dependent atrial flutter. Acute bidirectional CTI block was achieved in nearly all patients, with a low complication rate and high freedom from recurrent flutter at mid-term follow-up. The findings suggest that PFA is an effective non-thermal alternative for typical atrial flutter ablation, though long-term durability and comparisons with conventional thermal energy sources require further investigation.    Learning Objectives Describe the procedural success rates and safety profile of pulsed field ablation for CTI-dependent atrial flutter. Compare pulsed field ablation with traditional thermal ablation strategies for typical atrial flutter. Discuss the role of emerging ablation technologies in the management of supraventricular tachyarrhythmias.    Article AuthorsJuan F. Rodriguez-Riascos, MD, Hema S. Vemulapalli, MBBS, Poojan Prajapati, MBBS, Padmapriya Muthu, MBBS, James Y. Kim, MD, Dan Sorajja, MD, Win-Kuang Shen, MD, Hicham El Masry, MD, Mayank Sardana, MBBS, MD, Arturo M. Valverde, MD, Thomas M. Munger, MD, and Komandoor Srivathsan, MD Podcast ContributorsSenthil Thambidorai, MD, FHRS Lee Karl Thien, MD, CCDS Deep Chandh Raja, MBBS, MD, PhD   All relevant financial relationships have been mitigated. Host and Contributor Disclosure(s): D. Raja Nothing to disclose.   S. Thambidorai Nothing to disclose.   L. K. Thien Nothing to disclose.   Staff Disclosure(s) (note: HRS staff are NOT in control of educational content. Disclosures are provided solely for full transparency to the learner): S. Sailor: No relevant financial relationships with ineligible companies to disclose.

Most people focus on how much protein they eat, but Oliver Amdrup-Chamby, founder of health and wellness supplement brand Puori, argues the bigger question is whether your protein source is potent enough to support muscle as you age, and clean enough to use daily. He explains why leucine matters for muscle protein synthesis, and why plant and animal proteins can look very different once you factor in calories, volume, and digestibility. Then the conversation turns practical: what “third-party tested” should actually mean, why powders can concentrate contaminants, how to see through BS marketing, how to avoid toxins and more. Special Thanks to Our SponsorsOur Place: The top cookware brand for beautiful, non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com. Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.Puori Grass Fed Whey Protein: 21g of whey protein per serving from grass-fed cows, with 6g BCAAs and 2.4g leucine, free from hormones, GMOs, and pesticides. Use code AGEIST at puori.com/AGEIST to get 32% off Puori Grass-fed Whey Protein when you start a subscription.Key Moments“I want to tell you right out the gate that the key is to get your proteins from food.”“We used rice protein, we had to cancel it because we couldn't, even with our system in place, find the raw ingredients that we consistently saw as clean enough to hit the standards we wanted.”“We test every single batch, that's correct. You've got it right.”Connect with OliverPuoriLinkedInConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

We're joined by Michael Green, an elite-level physio who's worked in professional football across different clubs and projects, including time with the FA and supporting players through PFA rehab pathways. We get into what actually happens after a “routine knock” turns into months out, why ACL timelines are never as simple as fans want them to be, and why hamstrings are basically their own medical universe. Michael also tackles the big Spurs talking points: pitch surfaces, fixture congestion, intensity of playing style, rotation, injections and why you sometimes need weeks to know if they've worked. Plus, the bit nobody talks about enough: how stress, sleep and mental load can quietly push players towards injury. Learn more about your ad choices. Visit podcastchoices.com/adchoices

We're joined by Michael Green, an elite-level physio who's worked in professional football across different clubs and projects, including time with the FA and supporting players through PFA rehab pathways. We get into what actually happens after a “routine knock” turns into months out, why ACL timelines are never as simple as fans want them to be, and why hamstrings are basically their own medical universe. Mike also tackles the big Spurs talking points: pitch surfaces, fixture congestion, intensity of playing style, rotation, injections and why you sometimes need weeks to know if they've worked. Plus, the bit nobody talks about enough: how stress, sleep and mental load can quietly push players towards injury. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Jennifer Walsh explains how beauty is more than pleasant—it's biologically necessary. In this episode, she breaks down neuroaesthetics, the science of how art, nature, and well-designed environments influence our nervous systems and cognitive performance. Walsh shares actionable tools for using sound, texture, and light to regulate stress and spark creativity. Her insights reveal why small shifts in our surroundings can lead to greater emotional clarity, calm, and productivity.How long will you live? Take our quiz today to find out!Special Thanks to Our SponsorsPuori Grass Fed Whey Protein: 21g of whey protein per serving from grass-fed cows, with 6g BCAAs and 2.4g leucine, free from hormones, GMOs, and pesticides. Use code AGEIST at puori.com/AGEIST to get 32% off Puori Grass-fed Whey Protein when you start a subscription.Timeline Nutrition: Our favorite supplement for cell support and mitochondrial function. Listeners can now get 20% off their first Timeline purchase by using the code “AGEIST” at checkout at TimelineNutrition.com/ageist.Our Place: The top cookware brand for beautiful, non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com. Key Moments“Beauty, nature, and art are biological needs—not just luxuries.”“If you seek beauty every single day, you will find it.”“We're optimizing and biohacking our lives to death instead of slowing down and witnessing the beauty around us.”Connect with Jennifer WalshInstagramWebsiteConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

Dr. Lynn Marie Morski returns to discuss the fast-evolving science and practical application of psychedelics, for mental health and longevity. We unpack new studies on psilocybin's potential to influence cellular aging—like preserving telomere length—and the promise of non-hallucinogenic neuroplastogens for stroke recovery and mental flexibility. Lynn Marie also gets into why “heroic doses” may be counterproductive and how personalizing your set, setting, and compound may be key to safe and effective outcomes. This conversation is a must-listen for anyone curious about cognitive reinvention, therapeutic psychedelics, and how to make informed, safe choices in this complex field.How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!Special Thanks to Our SponsorsOur Place: The top cookware brand for beautiful, non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com/ageist. Fatty15 – C15 is the first essential fatty acid to be discovered In 90 years. Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter code: AGEIST at checkout.Puori Grass Fed Whey Protein – 21g of whey protein per serving from grass-fed cows, with 6g BCAAs and 2.4g leucine, free from hormones, GMOs, and pesticides. Use code AGEIST at puori.com/AGEIST to get 32% off Puori Grass-fed Whey Protein when you start a subscription.Key Moments“There is nothing heroic about doing too many grams of psilocybin.”“We want to shake up the snow globe and have the snow come back down into a nice landscape—not shake the snow globe and break it.”“If it can preserve telomere length… now we have all these other mechanisms by which it might have beneficial actions.”Connect with Dr. Lynn-MariePsychedelic Medical Association WebsiteInstagramPsychedelic Medicine PodcastConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

We've hit the halfway point of the A-League Women's 2025-2026 season, so ESPN's The Far Post's Samantha Lewis, Anna Harrington and Angela Christian-Wilkes are checking in on the big stories so far. We mull over the big questions like: are Sydney FC not good? Are Canberra United good? What's wrong with Melbourne Victory? We also chat through the PFA's Ready For Take-Off report, give a boot, and pay tribute to some legends of the game. We acknowledge the traditional custodians of the land on which this podcast was recorded and produced on: the Wurundjeri Woi Wurrung people of the Kulin nation and the Gadigal people of the Eora nation. Follow The Far Post on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, and ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Check out ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠espn.com.au⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or download the ESPN App. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this re-airing of a favorite episode, fitness coach Michelle MacDonald challenges everything you've been told about aging, strength, and what's "normal" after 40. She explains why sarcopenia isn't inevitable and how most women are deeply underserved by the current fitness industry. With personal stories including her own mother's 70-pound weight loss transformation, Michelle offers a blueprint for building strength, health, and confidence at any age. If you've ever felt underestimated by your doctor, trainer, or even yourself, this conversation will give you the clarity and tools you've been looking for.How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!Special Thanks to Our SponsorsPuori Grass Fed Whey Protein: 21g of whey protein per serving from grass-fed cows, with 6g BCAAs and 2.4g leucine, free from hormones, GMOs, and pesticides. Use code AGEIST at puori.com/AGEIST to get 32% off Puori Grass-fed Whey Protein when you start a subscription.Fatty15” C15 is the first essential fatty acid to be discovered In 90 years. Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter code: AGEIST at checkout.Our Place: The top cookware brand for non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com.Key Moments"Getting in fabulous shape is not rocket science.""Choose your hard. One of my favorite sayings.""There's an athlete in every woman, if she decides to believe that."Connect with Michelle MacDonaldWebsite: Wonder Woman CoachingInstagram: @michellemacdonaldofficialPodcast: Stronger by Design for WomenConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

Join Digital Education Committee Chair and podcast host Michael S. Lloyd, MD, FHRS, and his guests Kelvin C. Chua, MBBS, MD, FHRS, CEPS-A, and Rahul N Doshi, MD, FHRS, for this week's Lead episode, which was recorded live at APHRS 2025 in Kyoto, Japan. This discussion will review recent evidence on the feasibility and safety of pulsed field ablation (PFA) for coronary sinus and left atrial appendage isolation, as well as mitral isthmus ablation, focusing on both acute and chronic outcomes. Panelists will examine procedural considerations, lesion durability, and safety signals highlighted in the study, and explore how these findings may inform evolving ablation strategies for complex atrial arrhythmias.   Learning Objectives Summarize the acute and chronic feasibility and safety outcomes of pulsed field ablation (PFA) for coronary sinus isolation, left atrial appendage isolation, and mitral isthmus ablation as reported in the study. Evaluate procedural techniques and lesion durability considerations associated with using PFA in anatomically complex atrial structures. Assess the potential clinical implications of these findings for incorporating PFA into ablation strategies for complex atrial arrhythmias, including patient selection and risk mitigation.   Podcast Contributors Michael S. Lloyd, MD, FHRS Kelvin C. Chua, MBBS, MD, FHRS, CEPS-A Rahul N Doshi, MD, FHRS   Host and Contributor Disclosure(s): K.C. Chua•Nothing to disclose. R. N. Doshi•Speaking/Teaching/Consulting/Authoring: Boston Scientific, Kestra Inc., Abbott, Impulse Dynamics USA    M. S. Lloyd •Honoraria/Speaking/Consulting: Medtronic, Agra MedTech, Circa Scientific •Membership on Advisory Committees: Boston Scientific   Article for Discussion

***PLEASE READ** **CORRECTIONS** Correction 1: “Weight measurements are required for ALL SAILORS regardless of Step-1 outcome.” - From PRP Guide-4. (Dec 2025) Correction 2: “Waist measurements are to be measured at the umbilicus (belly button) from the right side of the body, keeping the tape parallel to the deck.” - From PRP Guide-4. (Dec 2025)   Troy Johnson pulled up to check the temperature after Aaron's comments about ATG. Aaron was around so the guys were able to get into a bunch of things. Why would we not open an episode out primary about fitness with recollections of “big back” activities? Is there any feeling better than getting plans cancelled on you? Time to get back on that couch and chill. Speaking of “chilling,” we have to tip our hats to ‘Stranger Things.' A 10-year run as a culturally iconic show on a streaming platform is not the easiest thing to do. The still could done our boy Caleb a little better. How much value should college have when it comes to Sailor of the Year boards? Are there any unwritten customs in the Navy that grinds your gears? Should Chiefs recite the ‘Chief's Creed' the same way we recite the ‘Sailor's Creed?' Should Sailors say the creed every day at quarters? The CNO recently held an All Hands Call and spoke about adding logic to leadership; the guys react. Are Meta Glasses authorized for wear in military uniforms? Should hardship rooms be available for Sailors who are dealing with lengthy domestic disputes? Is it time for AI to take over advancement or promotion boards? The guys finally get to these new PFA changes. Fortunately, Troy is here to make sure we don't stray too far from policy. Can't be football season without a little football talk. These and more topics are covered in this episode.     Do you have a “Do Better” that you want us to review on a future episode? Reach out at ptsfpodcast@gmail.com       Stay connected with the PTSF Podcast: https://linktr.ee/Ptsfpodcast   Follow Troy on all media outlets, buy his book, and more:   https://flow.page/fitnessleadertjay?utm_source=ig&utm_medium=social&utm_content=link_in_bio&fbclid=PAdGRleAPYgXtleHRuA2FlbQIxMQBzcnRjBmFwcF9pZA8xMjQwMjQ1NzQyODc0MTQAAac1QJ3CQMKeM-PIJROyn4w1x80mKtHqirZvMJccork19_vsREzL4yg-aT7R3w_aem_VAuRO7um5NpiowvC_Cepig       PTSF Theme Music: Produced by Lim0

After a near-fatal car crash, Jenn realized she had been living for others and it was time to live for herself. That moment launched her on a quest that made her the first woman to summit the second highest peak on every continent. In this episode, Jenn shares how raising seven kids prepared her for the logistical and emotional challenges of mountaineering, and how failure has become her teacher. Listeners will walk away with actionable insight on living intentionally, embracing discomfort, and redefining what's truly possible at any age.How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!Special Thanks to Our SponsorsOur Place: The top cookware brand for non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com. Fatty15 – C15 is the first essential fatty acid to be discovered In 90 years. Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. Get 15% off their 90-day subscription Starter Kit here or enter code: AGEIST at checkout.LMNT Electrolytes: Our #1 electrolytes for optimal hydration. Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.Key Moments"We don't get to choose when we die, but we absolutely get to choose how we live.""Accountability is love. When you put people in your life and they're accountable for you, that is a genuine act of love.""Being kind to yourself makes you stronger. Because the thing you're doing is hard enough."Connect with Jenn DrummondAll of Jenn's links: link.me/thejenndrummondConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

We had to pull up on y'all this Christmas, but please don't call this a Christmas special. Damo finds himself in yet another sticky situation, this time it's with Aaron. Before the results came out, the quotas were released, leaving many Sailors pissed about the low numbers. The guys discuss the disgust and what Billet-Based Advancement has to do with all of this. The Navy recently announced “The Trump Class,” complete with rail guns and laser beams. President Trump was feeling generous this holiday season and gave us two days off and “warrior dividends.” Oh yeah, what the hell are the Patriot Games? Why are people up in arms about the new PFA policy? Be careful what boots you're stepping in, come Jan 1st, you may be out of regs. Jake Paul took a beating, and Sailors may be fixing their own trouble calls in the barracks soon. The guys try to take a deep dive into the new Sailor of the Year grading sheet. What are your “isms?” Debra Newton was arrested last week, or was her name Sharon? One Navy Sailor was arrested for killing his two roommates, who were also Sailors, in Jacksonville, FL. In our ‘Do Better' segment, Damo wants some leaders to find some motivation, while Damon wants people to “train and explain.” The guys wrap with entertainment picks of the year. These and more topics are covered in this episode.   Pick of the Week: The War of Art (Steven Pressfield) https://stevenpressfield.com/books/the-war-of-art/       Do you have a “Do Better” that you want us to review on a future episode? Reach out at ptsfpodcast@gmail.com       Stay connected with the PTSF Podcast: https://linktr.ee/Ptsfpodcast       PTSF Theme Music: Produced by Lim0

Dr. Suzanne Gilberg is shifting the menopause conversation with science, compassion, and boldness. In this re-airing of one of our favorite episodes, she addresses common fears about hormone replacement therapy (HRT), especially the perceived connection to breast cancer, and unpacks what current data really shows. She also emphasizes the importance of keeping an open mind as science evolves and shares what excites her most about women's health and aging today. All in all, Dr. Suzanne's perspective encourages listeners to rethink how we define health, longevity, and female vitality in midlife and beyond.How long will you live? Take our quiz today to find out at ageist.com/longevity-quiz!Special Thanks to Our Sponsorsfatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.Our Place: The top cookware brand for non-toxic, PFA-free pots and pans. Make the switch today. Plus, Our Place is having their biggest sale of the year right now! Save up to 35% sitewide now through January 12th. Head to fromourplace.com/AGEIST to see why more than a million people have made the switch to Our Place kitchenware.Maui Nui: The cleanest, most nutrient-dense red meat out there—high in protein, rich in antioxidants, and ethically harvested. Their new, subscription-only ‘Ohana Reserve Aged Cuts are aged for 14 days to make for unforgettable flavor, plus their to-go venison sticks are perfect for healthy snacking. Right now, Maui Nui is offering a free 12-pack of their jerky sticks with your first order of $79 or more. Just go to mauinuivenison.com/ageist to grab yours.Key Moments“Science is not a religion. It is not a monolith, it is not unchanging and unmoving. That is not what science is. Science is a process of inquiry. Period. End of sentence.”“There's actually quite a bit of data on the potential health benefits of estrogen specifically in all of us and in breast cancer survivors.”“This is not a disease; this is a state of being alive. So you have options in terms of how you want to live and age well, whatever that means to you.”Connect with Dr. GilbergWebsiteInstagram (@askdrsuzanne)LinkedInYouTubeConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

GLP-1 use in HFrEF, left atrial posterior wall isolation during AF ablation, peri-device leaks for LAAO, new findings in post-cardiac surgery AF, and imaging before AF ablation are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Listener Feedback HYPERION trial https://www.nejm.org/doi/10.1056/NEJMoa2508170 ZENITH trial https://www.nejm.org/doi/full/10.1056/NEJMoa2415160 II GLP1 Use in HFrEF Effects of GLP-1s in Patients With HFrEF https://doi.org/10.1016/j.jchf.2025.102573 FIGHT Study https://jamanetwork.com/journals/jama/fullarticle/2540402 FIGHT Study Post-hoc Analysis https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.14862 Substudy of EXSCEL Trial https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.041659 III LA Posterior Wall Isolation Saga Failure of PW Wall Isolation by PFA with Epicardial Mapping https://doi.org/10.1016/j.jacep.2025.08.017 IV Peridevice Leaks After LAAO IMPRESSION LAAC Study https://doi.org/10.1016/j.jacep.2025.08.014 V Post Cardiac Surgery AF Monitoring of New-Onset AF After CABG https://jamanetwork.com/journals/jama/fullarticle/2839710 PACES trial https://clinicaltrials.gov/study/NCT04045665 VI TEE vs ICE Before AF ablation ICE vs TEE Study https://jamanetwork.com/journals/jamacardiology/fullarticle/2839370 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net