Podcasts about sparing

Welcome to the first episode of the Summer Protein Sparing Modified Fasting Series on the Optimal Protein Podcast. In this episode, Vanessa introduces the science, history, and practical application of protein sparing modified fasting, or PSMF, as a powerful tool for fat loss and body recomposition. Check out the Protein-Sparing Modified Fasting Library at ketogenicgirl.com and use code VANESSA for 20% off. Vanessa explains how PSMF was originally developed to help preserve lean body mass during severe energy restriction, why it differs from water fasting or traditional low-calorie dieting, and how prioritizing protein can help support satiety, fat loss, and muscle retention. This episode also explores the origins of PSMF with Dr. George Blackburn and Dr. Bruce Bistrian, its use in bariatric and physique-prep settings, and why strategic high-protein, lower-calorie days may be especially helpful for those who want to lose fat while protecting hard-earned muscle. You'll learn what a PSMF day can look like in practice, including protein targets, calorie ranges, lean protein choices, and how to combine PSMF days with maintenance days for a more sustainable approach. In this episode, Vanessa covers: What protein sparing modified fasting is Why preserving lean mass matters during fat loss How PSMF differs from water fasting The history of PSMF and its clinical origins Why protein supports satiety and metabolic rate How PSMF may support rapid fat loss without sacrificing muscle Practical meal structure, macros, and food examples Why resistance training is key for body recomposition Who PSMF may and may not be appropriate for Summer PSMF Series Re-Release Note: This episode was previously released on the Optimal Protein Podcast and is being re-released as part of the Summer Protein Sparing Modified Fasting Series. The PSMF Library is officially live

In this episode of the PRS Global Open Keynotes Podcast, the team from the Beaumont Hospital in Dublin Ireland discuss their technique for preparing the internal mammary vessels for microsurgical breast reconstruction without removing the costal cartilage. This episode discusses the following PRS Global Open article: "Rib-preserving Approach to Efficient Internal Mammary Vessel Preparation" by Safwat Ibrahim, Robert Browne and James D. Martin Smith. Read it for free on PRSGlobalOpen.com: https://journals.lww.com/prsgo/fulltext/2026/03000/rib_preserving_approach_to_efficient_internal.11.aspx Mr. Safwat Ibrahim is a consultant plastic and reconstructive surgeon Dr. Robert Browne is plastic surgery registrar at the Beautmont Hospital in Dublin, Ireland Your host, Dr. Damian Marucci, is a board-certified plastic surgeon and Associate Professor of Plastic Surgery at the University of Sydney in Australia. #PRSGlobalOpen; #KeynotesPodcast; #PlasticSurgery; Plastic and Reconstructive Surgery- Global Open The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

We live in an era of peak accumulation, and families are inheriting more than just memories—they are inheriting mountains of unwanted belongings. This "clutter crisis" is adding unprecedented logistical stress to the grieving process, leaving families exhausted before they even reach the arrangement room. How can funeral professionals help bridge the gap between grief and garbage? In this episode of A Brush with Death, host Gabe Schauf sits down with psychologist Katarina Blom and professional organizer Ella Engström, experts from The Gentle Art of Swedish Death Cleaning. They explore the deep psychological anchors of our possessions, the cultural differences in how we handle estates, and the physical roadblocks families face when clearing out a home. Gabe, Katarina, and Ella discuss how modern funeral homes can evolve from traditional service providers into "Legacy Curators." Listeners will learn how to identify clutter burnout during the arrangement conference, the practical value of the "Legacy Box" model, and how to build a trusted referral network to act as the "General Contractor of Grief." Whether you're looking for fresh preneed talking points or innovative at-need service opportunities, this episode provides actionable strategies to offer families the ultimate final gift: peace of mind. Key Takeaways: The psychological impact of physical and digital clutter on the grieving process. Shifting the funeral director's role to include post-service transition support. How to implement the "Legacy Box" to help families curate memories for visitations. Strategies for vetting local clean-out partners and organizers. Bonus from Ella:  After recording, Ella reached out with some additional information... Here are some thoughts that can help families or individuals get started with the process.  Whether you're sorting through your own belongings or going through a loved one's things, these questions can be a gentle way in. One of the key principles of death cleaning is that it's not just about things, it's about sharing meaning and memories while you still can. That's what makes it so much more than organizing. If you're sorting through your own belongings: 1. Start with one room, one category, not everything at once. 2. Do I use it? Do I love it? Does it make my heart sing? 3. Have I used this item in the last 12 months? 4. If I didn't have this — would I buy it again today? 5. When I hesitate about something, I ask myself: do I really want to deal with this again later or can I make the decision now? 6. If I'm still not sure, can I give myself 30 or 60 days before deciding? (The Dilemma Box method) 7. What do I actually want to pass on, and to whom? 8. Is there someone in the family who would truly treasure this? 9. What would make this home easier for the people I love, if they one day had to go through it? 10. What do I want my belongings to say about the life I lived? Key reminder: if the things you own start draining your energy instead of adding value, that's a sign it's time to take action. If you're helping a family member or going through a loved one's belongings: 1. What does this object mean to me — or what did it mean to them? 2. Am I keeping this out of love, or out of guilt? 3. What would feel like truly honoring this person — keeping everything, or keeping what really matters? 4. Is there someone in the family who would treasure this more? 5. Am I in charge here? (Yes you are. You have the right to make these decisions.) Remember: the memories of a loved one live in your heart, in the stories you share, and in the love they gave you — not in the objects they left behind. And letting go isn't about forgetting the past — it's about making space for the present and for what's ahead. Dare to have conversations with each other while you still can. It's actually a beautiful thing to discover what truly matters to the people you love. You might be surprised by what you find out. And remember: sorting through your own things is one of the greatest gifts you can give the people you love. Sparing them from that burden is an act of love and that's really what döstädning is all about.  

AP correspondent Julie Walker reports a violent tornado tears through an Oklahoma town, damaging 40 homes but sparing lives.

At least six tornadoes hit Oklahoma Thursday night, including one the National Weather Service rates as an EF-4 . The AP's Jennifer King reports.

Is your dog partaking in terrier sparing?  This week, Tara and Laura dive into the known competition of terrier sparing.  They break down what this competition is, why they believe it is inappropriate, and what behaviors it can cause in terriers that can feed the stereotypes about the breed.  Many people have a negative viewpoint on the terrier breeds, and unfortunately, some of those opinions can be caused by what humans have taught these dogs to do.Sponsored by K9 WorkingmindThis episode was edited and mastered by The WillaWoman. Our song "Working Minds" was also created by The WillaWoman.Hear more of her work here: https://tinyurl.com/TheWillaWoman

Discover how intra-arterial chemotherapy is saving children's eyes and transforming retinoblastoma care in North Texas. Learn more about the retinoblastoma treatment here. 

Økonom Silje Sandmæl er på besøk for å snakke om noe som angår oss alle, nemlig økonomi. Med utgangspunkt i sin egen oppvekst med begrensede ressurser, deler hun hvordan hun tidlig utviklet en forståelse for penger, og hvordan dette har formet både valgene hennes og hvem hun er i dag.Silje forteller om de første grepene hun tok for å få kontroll over egen økonomi, og gir konkrete råd til hvordan vi kan gjøre penger mindre skummelt, slik at vi blir tryggere og flinkere til å ta gode økonomiske valg. Hosted on Acast. See acast.com/privacy for more information.

Ronja er ei som har tatt økonomiske grep fra svært ung alder, noe som har gitt henne store muligheter! Hør fra denne reiseglade 24åringen som allerede har 2 boliger under sitt belte!Høres det spennende ut? Press play! Se samtalen på YouTube (kommer) Følg Ronja på instagram: @ungsparerRonjas shoutouts:Lise Vermelid (@pengesnakk)Sparing, investering, bevisst forbruk og økonomisk frihet (@sparestemning) Iren Mørk || Økonomi og sparing

Researchers have developed a magnetic device that uses spinning oscillating fields to selectively kill aggressive brain cancer cells while leaving healthy brain tissue completely unharmed. In this episode, I break down groundbreaking research showing how specific electromagnetic field patterns can target cancer's energy production systems. We explore what makes this approach so selective and what it means for the future of brain cancer treatment. In This Episode How spinning magnetic fields selectively destroy cancer cells Why healthy brain cells remain completely unaffected The mechanism targeting cancer cell energy production Featured Study Read the full study: Hambarde S, Pandey A, Baskin DS, Helekar SA See all studies at shieldyourbody.com/research

In this episode, we're diving into the hot topic of protein sparing modified fasting (PSMF) and why short, strategic “3-day sprints” can be a powerful metabolic reset. Ali shares how these brief hypocaloric phases may help accelerate body fat loss while supporting anti-inflammatory processes and increasing autophagy, the body's natural cellular cleanup system.  The literature consistently shows that most diets fail long term, with weight regain common within five years, and often much sooner with more aggressive interventions like GLP-1 medications or surgical approaches. In this conversation we explore who may benefit from protein sparing fasts, who should avoid them, where supplements fit in and how to implement this strategy. We also discuss research on autophagy. Also in this episode:  Beat the Bloat FREE Masterclass 4/7 Beat the Bloat Program starts 4/21 What is a protein sparing modified fast? A Systematic Review of Evidence on the Use of Very Low Calorie Diets in People with Diabetes - PubMed The protein-sparing modified fast for obese patients with type 2 diabetes What does a day of fasting this way look like? A protein sparing fast can be broken into 1 meal and 2 snacks or 2 meals or even 3 meals, but I typically do: Coffee with Pure Collagen and ½ scoop Whey Protect with 1 Tbsp heavy cream (26g protein, 150 cal) 1 jar FOND (15g protein 60 cal) 6oz filet of wild salmon (300 cal 33g pro) 1 jar of FOND  (15g protein 60 cal)  Naturally Nourished Teas Thoughts on dry fasting or water fasting  Does protein disrupt autophagy? A high protein meal does not change autophagy in human blood In Defense of Protein Effects Of Oral Glutamine on Inflammatory and Autophagy Responses in Cancer Patients Treated With Abdominal Radiotherapy: A Pilot Randomized Trial Bone Broth benefits Glycine Relieves Intestinal Injury by Maintaining mTOR Signaling and Suppressing AMPK, TLR4, and NOD Signaling in Weaned Piglets after Lipopolysaccharide Challenge Curcumin induces autophagy, inhibits proliferation and invasion by downregulating AKT/mTOR signaling pathway in human melanoma cells - PubMed Who should consider PSMF and who should not?  What supplements support PSMF? Detox Packs Multidefense  Relax and Regulate Berberine Boost Calm and Clear GabaCalm  

Dr. Kimberly Stevenson offers an orthopaedic surgeon's perspective on the muscle-sparing direct anterior approach (DAA) to total hip arthroscopy. DAA brings about a faster recovery than the classic posterior and lateral approaches and has the potential for a lower risk of dislocation.  Learn more about Kimberly Stevenson, MD 

Guest Dr. John Gore and host Dr. Davide Soldato discuss JCO article, "12-Month Results from the CISTO Study Comparing Radical Cystectomy Versus Bladder-Sparing Therapy for Recurrent Non-Muscle Invasive Bladder Cancer," which compares radical cystectomy and bladder sparing therapy for patients with recurrent high-grade non-muscle invasive bladder cancer. Dr. Gore and Dr. Soldato focus on the study's patient-centered approach, eligibility criteria, and quality of life after treatment. TRANSCRIPT The disclosures for guests on this podcast can be found in the show notes. Dr. Davide Soldato: Hello and welcome to JCO After Hours, the podcast where we sit down with authors from some of the latest articles published in the Journal of Clinical Oncology. I am your host, Dr. Davide Soldato, medical oncologist at Ospedale San Martino in Genoa, Italy. Today, we are joined by JCO author Dr. John Gore, urologist at Fred Hutch Cancer Center and professor of urology at University of Washington School of Medicine. Today, we will be discussing the article titled, "Twelve-Month Results From the CISTO Study Comparing Radical Cystectomy Versus Bladder-Sparing Therapy for Recurrent High-Grade Non-Muscle-Invasive Bladder Cancer." Thank you for speaking with us, Dr. Gore. Dr. John Gore: Thank you so much for having me. Dr. Davide Soldato: So, I just want to jump right in. We know that patients who are diagnosed with recurrent high-grade non-muscle-invasive bladder cancer can be treated with two different approaches. So, one is radical cystectomy, and the other is bladder-sparing therapy. I just wanted to understand: what was the gap that you were trying to fill with this study? In particular, one point that is very important is that this study is very centered on the preference of the patients. Why did you choose this endpoint instead of going for more solid oncology-based endpoints? Dr. John Gore: Yeah, so CISTO was a study that was derived really organically from patient engagement. I think as a clinical gap in care, making a decision about when to pursue radical cystectomy for patients with non-muscle-invasive bladder cancer is a tough decision for us as clinicians. We did some engagement work partnered with the Bladder Cancer Advocacy Network and my partner Angela Smith, and found that it is also a huge gap for patients. You know, they are very anxious about recurrences, and the decision about when to take out the bladder is a very difficult one. We did an evidence synthesis and found that evidence guiding this decision is fairly limited. The reason we chose more of a patient-reported endpoint is several-fold. One is that we, as part of our engagement work, also worked with our patient survey network to identify outcomes that were important to patients. Some of those are the same outcomes that we care about as clinicians - recurrence-free survival and metastasis-free survival - but several outcomes came out that were more patient-centered. These were patient-reported outcomes such as the burden on my finances, the burden on my caregiver or loved one, and the ability to return to physical activities that are important to them. Part of what is unique about CISTO is that this was a contract with PCORI where we knew we would only have about 12-month outcomes for the majority of our patients. That is too early to really derive a lot of the clinical outcomes, but we are able to answer that patient-centered question of, "Am I going to be able to return to physical activities that are important to me?" And that was the genesis of that as the primary endpoint. Dr. Davide Soldato: So, who were the patients that were eligible to participate in the CISTO trial? What were the key eligibility criteria? This is very particular to this study because this was actually an observational study. Why did you think that such a pragmatic approach still can inform us on what is the best treatment approach for these patients? Dr. John Gore: The intent of CISTO was not necessarily to focus on the tightly defined BCG-unresponsive patient population. That is a clearly important patient population, but every day we are all faced in our real-world practice with patients with challenging, high-grade recurrences that don't fit neatly into that BCG-unresponsive box. The reason we chose a broader inclusion was to help doctors and patients answer these same questions they have when it doesn't fit nicely into this BCG-unresponsive category. You know, maybe their BCG exposure was two years ago, but now they are having a recurrence after intravesical chemotherapy. That is no less challenging a clinical conundrum, and we wanted to be able to enroll those patients. Other key inclusions were that all of the patients in CISTO had to have BCG at some point, and they had to have recent exposure to some adjuvant instillational or intravenous therapy like pembrolizumab. We also had some exclusions that were important. They couldn't be participating in a phase 2 clinical trial, and they couldn't have had a prior upper tract urothelial cancer. The other point about the observational trial design is I think a really important one. Part of our engagement work also asked patients about their willingness to randomize. There is a ton of literature in our history of trials that failed to accrue well when they were comparing a large-scale surgical intervention with a more conservative management strategy. What we found is only about 10% of patients would be willing to randomize when the clinical comparison is between radical cystectomy and bladder-sparing therapy. So it was very clear that an observational study design was the only way we were going to get evidence to inform clinical care when one of the key comparators was radical cystectomy. And so that is why we utilized the observational trial design. Dr. Davide Soldato: Starting to go deeper into the results, you mentioned before that the endpoint you chose for this trial was really centered on what patients thought was more important to them. In particular, the primary endpoint of the study was physical function as measured by the EORTC QLQ-C30 questionnaire. I just wanted to understand: first, did you have a solid hypothesis regarding how physical function could be impacted by either radical cystectomy or bladder-sparing treatments? And second, what were the key results of the study? Dr. John Gore: We figured that at 12 months after enrollment, given the burden and morbidity of a radical cystectomy, that patients in the radical cystectomy arm would have worse self-reported physical functioning than patients in the bladder-sparing therapy arm. We did hypothesize that some of our secondary outcomes might potentially be better after radical cystectomy, such as recurrence-free survival and potentially some other cancer-specific outcomes, because it is a more definitive management strategy. For our primary endpoint, however, we hypothesized that it would be worse. What we found, and the key finding of our study, is that at 12 months after enrollment, physical functioning was not different between patients undergoing radical cystectomy and patients undergoing bladder-sparing therapy, which is just important in terms of clinical counseling because it just means that you can tell your patients, "Gosh, if we could fast-forward your life six to nine months after this procedure, your physical functioning would be similar to as if you had been able to keep your bladder." Dr. Davide Soldato: And you mentioned that there were some key secondary endpoints of the study, which included both other dimensions of quality of life and also hard clinical outcomes. We mentioned metastasis-free survival, for example. Going a little bit into the key secondary quality of life outcomes, we know that radical cystectomy can impact physical functioning, but we also know that bowel, sexual symptoms, and also genitourinary symptoms might potentially be impacted by this type of treatment. We also know that, especially in a system like the US, financial toxicity can be a significant burden for patients. Considering the two different approaches, was radical cystectomy better also in other key secondary quality of life outcomes, and was financial toxicity different between the two arms? Dr. John Gore: Thank you for highlighting some of the really important secondary outcomes that I think are really important to trying to figure out what's best for your patients. Some of the main ones were some of the bladder cancer-specific quality of life outcomes you highlight. Urinary quality of life was worse at enrollment in patients in the radical cystectomy arm but was no different 12 months after. What is unique about how we measure that is we used an instrument called the Bladder Cancer Index because we're comparing a population of patients who have lost their bladder with a population of patients who have retained their bladder, and there are different considerations by gender. And so that instrument is agnostic to urinary diversion status and gender. We found that bowel function and sexual function were worse in the radical cystectomy arm. It appeared that bowel functioning was getting better to the point of near equivalence at 12 months in the radical cystectomy arm but was still inferior to bladder-sparing therapy, and that probably relates to the fact that we use the bowel as part of the urinary diversion, and that causes some transient disruption in bowel function. Financial toxicity is an outcome we weren't initially planning on having as part of the CISTO study, but based on that patient feedback, we made that one of our key secondary outcomes. That actually demonstrated superiority in the radical cystectomy arm. I think it's important that we remember that when we do bladder-sparing therapy, those patients are predisposed to a number of visits to our office, whether they're for instillational therapies or cystoscopy surveillance visits. Sometimes that involves the patient themselves, and sometimes that involves a caregiver. We live in an area with a very large geographic catchment, so sometimes that involves overnight hotel stays and airfare. It can be a particular burden, as you made mention, especially in our healthcare system. Dr. Davide Soldato: Going back to the quality of life dimensions and especially considering the different treatments, 50% of the patients received radical cystectomy with robotic surgery. Did you look a little bit into whether the type of surgery that they received might potentially impact on these dimensions of quality of life? Dr. John Gore: These are some questions that a lot of urologists have asked us in the surgical arm, related to surgical approach, so robotic versus open, and urinary diversion type. We sometimes reconstruct the urinary tract with an incontinent diversion called an ileal conduit where the urine drains tonically into a bag, and we sometimes do a continent diversion where someone typically will have a neobladder, where you reconstruct a sphere reservoir out of intestines and sew it to the urethra. About 20% of patients in the radical cystectomy arm in CISTO had a neobladder. We have not yet looked at specific surgical factors and some of those outcomes. That is one of the secondary analyses that we have planned, but we have not drilled into how different surgical approach factors can affect some of our outcomes. Fortunately, we have about 200 patients in the radical cystectomy arm, so it's enough patients that hopefully we can look at some of those factors in the future. Dr. Davide Soldato: Going back to the clinical endpoints, you mentioned that several of these were measured. There was metastasis-free survival, cancer-specific survival, and progression-free survival. We now have the data at 12 months. I am just wondering if you can comment on those when comparing the radical cystectomy with the bladder-sparing techniques. Dr. John Gore: I think importantly, bladder cancer-specific survival was very high in both arms, over 95% at one year. So both patient populations do very well in terms of cancer-specific and overall survival at one year. You know, when you take out the bladder, you're taking out a big source of recurrences. Not surprisingly, there was a marked reduction in recurrences in the radical cystectomy arm, so they had better recurrence-free survival. There actually was worse progression-free survival in the radical cystectomy arm, but there is a big asterisk to that. As you noted, it is an observational study, and one of the areas of imbalance in the study is that we had higher cancer severity in the radical cystectomy arm. So there was about a 20% rate of progression at the time of radical cystectomy to muscle-invasive and node-positive disease. Of those progressions, the overwhelming majority of them were progressions at the time of radical cystectomy, which I think speaks to a couple of important factors. Number one is the challenge in staging these patients. Our staging of non-muscle-invasive bladder cancer is very reliant on our resection. And so there is this risk of understaging our patients. Number two is just the challenge of decision making, that we fear losing our window of cure in this patient population, which is why we try to steer some patients toward radical cystectomy, and that progression figure kind of speaks to that. Dr. Davide Soldato: Also, one of the factors that was most common in the patients who received radical cystectomy was the presence of other high-risk features. For example, non-urothelial histology, which I think is something that in clinical practice we tend to fear a little bit in terms of recurrence, and so it might potentially bias a little bit towards proposing more strongly radical cystectomy to the patient. Another thing that I wanted to have a comment on, so this is not really in the paper, but I think it speaks a little bit to how the data will evolve over time. Do you imagine these clinical outcomes changing over time, and do you think that with higher maturity of these endpoints, this study might be even more informative when counseling patients regarding what they are obtaining with a radical cystectomy versus the other type of treatments? Dr. John Gore: You know, I think in this cancer universe, 12-month outcomes are great, but I think we all want to see two-year and five-year outcomes. We're very fortunate to supplement the work that we've done in the initial CISTO study, we're very fortunate that we've gotten supplementary funding from the National Cancer Institute to get long-term outcomes in this patient population. So we are continuing to follow all of our CISTO study patients to get two-year and five-year outcomes. What we expect to find is the accrual of new events in the bladder-sparing therapy arm. About 7% of patients in the bladder-sparing therapy arm underwent cystectomy in the first year, but that number will probably go up either as they have recurrences or progression events. We definitely expect the recurrence-free survival to continue to have superiority in the cystectomy arm, but we probably will see the progression events equilibrate as more progression events accrue in the bladder-sparing therapy arm. Maybe by five years, we hypothesize that we'll see clinical superiority in the radical cystectomy arm. By then, we might also see mortality events that separate bladder cancer-specific survival and overall survival between the two arms potentially. But we don't know. Hypothetically, cystectomy has its own downstream risks. It is a major reconstruction with some metabolic sequelae and renal functional sequelae, and so there may be some general medical events that accrue in the cystectomy arm that are also impactful. Dr. Davide Soldato: One other thing that I think should be complimented on this study is that you also looked at several other endpoints that might be important for patients. For example, anxiety symptoms and depression symptoms. Dr. John Gore: Yeah, I think one of the other key secondary outcomes we looked at were mental health outcomes. We utilized the PROMIS domains of anxiety and depression. Not unexpectedly, our radical cystectomy arm patients exhibited higher anxiety symptoms and higher depression symptoms at enrollment. What we found is at 12 months, they actually had significantly lower anxiety and depression than patients in the bladder-sparing therapy arm. We hypothesized in this paper that that actually relates probably mostly to cancer-specific anxiety. You know, when you experience this cavalcade of recurrences, it just breeds an anxiety about adverse cancer-specific outcomes, and by taking out the bladder, you kind of eliminate this prevalent source of anxiety. We followed up the study with a qualitative piece where we interviewed 50 patients and 20 caregivers. Based on those interviews, and that's just a sample of the patient population, it did seem to be cancer-specific anxiety that was driving a lot of those responses. Dr. Davide Soldato: I would like to end with a methodological consideration on your part because we said that this was an observational study. Frequently we tend to think that observational studies come with a lot of bias, and so we tend to downgrade a little bit the results. But I think that a lot of the merit that goes in the CISTO study that was published in the JCO, and I think it also speaks to the fact that this is very high-quality data, comes with the fact that the methodology behind this study was really robust in terms of informing us. Even with this observational study that, as you said, was the only one that we could perform considering the patient population. So just a comment on your part also to speak to the solidity of the data that was published. Dr. John Gore: Importantly, you know, if you look at ClinicalTrials.gov or other sources, CISTO is the only trial that has radical cystectomy as a major comparator. In many ways, this study is our only source of evidence for radical cystectomy. So we'd rather have flawed observational evidence than no evidence at all. We all experience flaws of our RCTs as well. They tend to be these narrowly defined patient populations that may not match the patient in front of you. So I think there are unrecognized flaws on the other side as well. The way that we try to counterbalance that, and none of these techniques are perfect, but we used a strategy called 'targeted maximum likelihood estimation'. Like many methods, such as propensity scores or instrumental variable analysis, what we're trying to do theoretically is coax randomization from non-randomized data. And TMLE, which is the technique we use, tends to be pretty robust to that. So it's the best available way that we can try to counterbalance the bias based on age and clinical severity between the two patient arms. I also think what's important about this is that even when there are biases, I think we are able to infer those out and still extract meaningful details from the data. So even with the biased data, I think we all glean some really important clinical learnings from it. Dr. Davide Soldato: Absolutely, but I would also say that in terms of observational data, the work that you have done is really something that makes us quite confident about what you found in the CISTO study. So with this, I would like to thank you again for joining us today. Dr. John Gore: Thank you so much, and thank you for highlighting the CISTO study. We are very excited about the data. Dr. Davide Soldato: So Dr. Gore, we appreciate you sharing more on your JCO article titled, "Twelve-Month Results From the CISTO Study Comparing Radical Cystectomy Versus Bladder-Sparing Therapy for Recurrent High-Grade Non-Muscle-Invasive Bladder Cancer." If you enjoy our show, please leave us a rating and review and be sure to come back for another episode. You can find all ASCO shows at asco.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Guest Disclosure Dr. Gore:Consulting or Advisory Role: Astellas Pharma  

Iben er våryr, Jens Elwyn må kanskje bade naken på Sørenga etter et veddemål, og setter i gang en diskusjon rundt «ironisk hockeysveis», mens Mar Valo vil vite om medlobbyistene hens vil smashe or passe beskrivelser av objekter (m.m.)…P.S. Vi fikk en uventet gjest i studio (vi var live på radio, noe vi nesten aldri er)! Men hvem var denne mystiske gjesten? Det finner du ut ved å lytte til denne episoden

This episode is sponsored by Timeline. Timeline - Support your cells and how you age with Mitopure® Gummies from Timeline. Visit https://timeline.com/FLIPPING50SHOW and save up to 39% off your Mitopure® Gummies. Other Episodes You Might Like: Previous Episode - Gut Health and Migraines: Your Mother's Migraines? Next Episode - GLP-1 Medications for Weight Loss: A 42-Year Fitness Professional's Honest Take More Like This: What Is Sarcopenia and How to Avoid Sarcopenia In Menopause Can You Fast and Prevent Muscle Loss in Menopause and Beyond? Resources: Don't know where to start? Book your Discovery Call with Debra. Leave this session with insight into exactly what to do right now to make small changes, smart decisions about your exercise time and energy. Use Flipping 50 Scorecard & Guide to measure what matters with an easy at-home self-assessment test you can do in minutes. Sparing muscle loss during fat loss is what every midlife woman needs to hear before trying another fasting trend.  Whether intermittent fasting truly delivers fat loss benefits — or if it quietly costs you the very muscle that protects your metabolism, we'll talk about the latest 2025 research reveals about protein-sparing modified fasting, autophagy, ketones, and why calorie deficit alone isn't the full story.  In this episode, know if fasting fits your body or not — if you're in perimenopause or postmenopause and want better body composition without wrecking recovery. Sparing muscle loss during fat loss isn't about eating less and hoping for the best — it's about using science strategically to protect strength, metabolism, and longevity. If this episode made you flip your workout routine — share it!

Can aqueductal stenosis be treated through a minimally invasive endovascular approach without transgressing brain parenchyma? In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, speaks with neuro-interventional radiologist Dr. Michal Obrzut¹ about a neurointerventional approach to the management of obstructive hydrocephalus secondary to aqueductal stenosis. The author describes the underlying concept, technical feasibility in cadaveric models, and potential implications for minimally invasive neurosurgical practice. Link to the discussed paper: "A novel neurointerventional subarachnoid aqueductoplasty technique for the treatment of aqueductal stenosis: a cadaveric feasibility study"   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.   (1) Neurosurgery, Cleveland Clinic Florida, Weston, Florida, USA          

[1 Samuel 26-27] The path of faith has a better destination than the path of fear

Arild Vikan

Soul Custody: Sparing Children from the Hidden Toll of Divorce with Pamela Henry, author of Soul Custody.  Guest Website: https://soul-custody.comEpisode Summary:Divorce doesn't just end a marriage—it reshapes the emotional world of everyone involved, especially children. In this powerful and deeply personal episode of Linda's Corner, host Linda Bjork welcomes Pamela Henry, an expert in early childhood education, family systems, and shared custody parenting. She's also the author of Soul Custody: Sparing Children from Divorce, a transformative guide for families navigating the emotional terrain of separation.Pamela shares her own story: a desperate desire to escape her marriage that eventually led to a profound revelation—she wasn't really trying to escape her husband, but the pain of her own unresolved childhood trauma. As a survivor of sexual abuse by her father, Pamela unconsciously projected her confusion, hurt, and rejection onto her relationships—ultimately impacting her marriage and her children.Now, Pamela helps others understand the deeper emotional roots that can influence the decision to divorce. She invites listeners to pause, reflect, and heal before making choices that carry lifelong consequences.In this episode, we explore:The often unseen emotional cost of divorce on childrenHow childhood trauma can shape adult relationshipsWhy healing yourself is key before trying to fix or escape a relationshipThe importance of self-compassion, transparency, and owning our mistakes as parentsHow to create a healthier future by confronting the pastThis episode is a compassionate, thought-provoking invitation to approach relationships with deeper awareness and responsibility. If you're navigating a difficult relationship or healing from your past, this conversation is for you.Resources & Links:

In this episode, I open up about the emotional close to my year, answer your questions about protein sparing fasting, and share what I've learned about metabolic health, stress, and longevity—especially for women navigating busy, high-stress lives. I also dive into my own recent health journey, including surprising bloodwork results, and break down the latest research on exercise for longevity. Join me as I reflect, share practical tips, and invite you to step into the new year with intention and self-care.Chapters:[01:28] Honoring My Pup & Emotional Updates[01:57] Listener Questions: Protein Sparing Fasting[02:26] Beyond Calories: Metabolic Health & Longevity[02:57] Coping with Stress, Hormones, and Grief[03:50] Why I Tried Protein Sparing Fasting[04:47] Reset, Not a Crash Diet[05:58] Building Muscle & Sustainable Health[07:25] Bloodwork Insights & Lean Mass Hyper Responder[13:15] Exercise, Longevity, and Intensity[16:33] Cardio, Cortisol, and Muscle Preservation[19:10] Sprint Intervals & Practical Tips[21:24] Sustainable Wellness & Program InvitationSay Hi to Ciara:Ciarafoy.com @ciarafoyinc Don't forget to leave a rate & review!

FROM WAKE MEDIA:Yuval Noah Harari tells the WEF: "Control of data might enable human elites to do something even more radical than just build digital dictatorships.""By hacking organisms, elites may gain the power to re-engineer the future of life itself.""If indeed we succeed in hacking and engineering life, this will be not just the greatest revolution in the history of humanity, this will be the greatest revolution in biology."

A father and his nine-year-old son are found shot inside a home in Ohio in what police now call a possible murder-suicide. A Tennessee death row inmate who raped and killed a college student in Chattanooga nearly four decades ago is now set to die by lethal injection after declining to choose his execution method. Drew Nelson reports.See omnystudio.com/listener for privacy information.

In this episode of HSS Presents, Dr. Josh Bram speaks with orthopedic surgeons Dr. Peter Fabricant and Dr. Daniel Green about ACL reconstruction in skeletally immature athletes. They explain why traditional techniques risk growth plate injury and discuss specialized physeal-sparing procedures, including the modified MacIntosh IT band technique and all-epiphyseal reconstructions. The conversation highlights patient selection, imaging strategies, and graft choices that reduce re-injury rates while protecting long-term knee health. With insights from large multicenter studies and decades of pediatric sports medicine experience, the experts share best practices for safely returning young athletes to play.

Sign up to Mondays Matter Xmas Edition https://www.mikkiwilliden.com/mondays-matterMiki dives into the often-avoided topic of digestion during protein-sparing modified fasts (PSMF). If you've ever wondered why your gut behaves differently on these lean-protein days, this one's for you. Miki explains what's happening physiologically—from changes in bile flow and microbiota to electrolyte shifts—and how these can lead to constipation or, less commonly, diarrhea. She walks through practical, evidence-based strategies to get your digestion back on track, including hydration, magnesium types, vitamin C dosing, bitters, and soothing supports like slippery elm. Learn how to troubleshoot gut symptoms so your PSMF days feel as good as they look on paper.Highlights:Why constipation is common on low-fat, low-fibre, high-protein daysHow bile flow, hydration, and electrolytes affect gut motilityMagnesium, vitamin C, and bitters as tools for smoother digestionGentle fixes for diarrhea and when to adjust supplementsThe transitional nature of gut changes during PSMF Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

Topics covered:  Are oral GLP-1s as effective as injectables? What's the deal with the new report on protein powders containing lead? Should I worry about not having carbs with my protein after a workout? Are energy drinks really killing my gains in the gym and workouts? Consumer Report on protein powders Podcast with Dyllon Sanford on GLP-1-Part 1.  European Food Safety Authority

An audio summary of "Robot-assisted partial nephrectomy using the HugoTM RAS System: first multicentre study and Tetrafecta achievement" by Prata et al. Summary generated by Pub2Post. Read the full article here tnyp.me/82mBF0XA

Elliot Sweeney has been a psychiatric nurse for over two decades. Now he has written a book about his experiences: ‘We Don't Use Words Like Crazy - A Life On The Frontline Of Mental Health.' His moving, and often funny, memoir pulls back the curtain on what the job's really like, showing why we need more compassion for people who are struggling and the professionals who try to help them every day.To donate to my fundraiser for CALM's Stay Tuned Campaign, please click this link.Suicide is the biggest killer of men under 50 in the UK. Sparing a few quid for CALM helps them fund their essential service to help bring that rate down. Hosted on Acast. See acast.com/privacy for more information.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on IL-1 Pathway Inhibition in Recurrent Pericarditis Management: Real-World Adoption of Corticosteroid Sparing in RESONANCE.

A gynaecological cancer diagnosis shouldn't take away the right to plan your future. This episode delves into surgical options and fertility considerations, highlighting minimally invasive versus open surgery, fertility-sparing treatments, hormonal therapy pathways, and the emotional and reproductive impacts of surgical decisions.Through lived experience from Mina and expert guidance from Professor Alison Brand AM, we explore how surgical innovations can support both health and future family planning. Ask questions, explore your options, and take an active role in your care.

Content Note / Trigger Warning: The first two-thirds of this episode focus on Maria Emmerich's expertise in helping thousands of people who are overweight, obese, or struggling with metabolic health to lose weight and dramatically improve their health and lives. In the last third of the interview, Maria shares her very recent personal experience with struggling with restrictive dieting, and her courageous journey of weight regain. Please listen with care if these topics around disordered eating may be sensitive or triggering for you. See *RESOURCE below if you or someone you care about needs support. Unlock sharper focus and support long-term brain health with Ketone-IQ—clean brain fuel for deep work, mental clarity, and sustained energy with no crash. Get 30% off your subscription, plus a free gift with your second shipment at Ketone.com/vanessa. Today's guest is Maria Emmerich, internationally renowned nutritionist, best-selling author, and an expert in her version of integrating 1-2 Protein Sparing Modified Fast Days (PSMF Days) in a week to create a weekly caloric deficit while protecting muscle and metabolism, including re-feed days to balance out the week. In this episode, we cover: What PSMF Days are and how they differ from the sugar diet or fasting How PSMF Days preserve lean muscle while accelerating fat loss The role of stall foods like nuts, dairy, and nut flours in holding back fat loss Client strategies for satiety, electrolytes, and exercise integration The science behind metabolic adaptation, and refeeds Why higher protein intake and supplements like creatine are key for recomposition Maria's personal story of becoming too lean, regaining weight, and how it reshaped her coaching philosophy This episode is packed with practical strategies from Maria's decades of experience helping people transform their health — and also offers a very candid look into her own personal journey. IQBAR is offering my podcast listeners 20% OFF all products, plus FREE shipping! IQBARs are packed with plant protein, fiber, and brain nutrients like Lion's Mane and omega-3s, keto-friendly, low in sugar, gluten-free, dairy-free, and soy-free. To claim your discount, just text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. NEW! Support your strength and muscle goals with PUORI Creatine+ — a clean, effective creatine monohydrate supplement enhanced with magnesium and vitamin B12. Get 20% off at puori.com/VANESSA Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide  Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at https://ketogenicgirl.com with the code VANESSA Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen. *RESOURCE: If you are in the United States and you or someone you love is struggling with disordered eating, support is available. You can call the National Eating Disorders Association (NEDA) Helpline at 1-800-931-2237 or visit nationaleatingdisorders.org for resources.

HR2 New Tax on Remittance Dollars, Nancy Mace Sparing With Protesters 8-27-2 by John Rush

MOST PEOPLE HAVE HEARD OF “RAPID FAT LOSS” DIETS…BUT FEW UNDERSTAND THE SCIENCE BEHIND THEM.On this week's episode of the CHASING CLARITY HEALTH & FITNESS PODCAST, I'm joined by none other than Lyle McDonald, author of The Rapid Fat Loss Handbook and one of the greatest thought leaders in evidence-based nutrition.Together, we dig into the origins, evolution, and practical application of Protein-Sparing Modified Fasts (PSMFs) and Lyle's updated insights on RFL. HERE'S WHAT WE COVER:WHAT IS A PROTEIN-SPARING MODIFIED FAST (PSMF) & HOW DOES IT WORK?THE HISTORY OF VERY-LOW-CALORIE DIETS (VLCD) & THE ORIGINS OF PSMFWHAT INSPIRED LYLE MCDONALD TO WRITE THE RAPID FAT LOSS HANDBOOK?HOW RFL IMPROVES UPON THE CLASSIC PSMF MODELWHY PROTEIN NEEDS TO SCALE UP DURING A CALORIE DEFICITHOW A DEFICIT IMPACTS MUSCLE PROTEIN BALANCE (MPS VS. MPB)HOW TO SET PROTEIN INTAKE ON RFL BASED ON BODY FAT % & ACTIVITY LEVELESSENTIAL FATTY ACIDS ON RFL- WHY EPA & DHA ARE NON-NEGOTIABLEFOOD SOURCES VS SUPPLEMENTATION FOR OMEGA-3S DURING RAPID FAT LOSSWHY VEGETABLES MATTER ON RFLWHOLE FOODS VS LIQUID DIETS IN RAPID FAT LOSS PROTOCOLSHOW TO SCALE THE DEFICIT SIZE BASED ON BODY FAT PERCENTAGE & ACTIVITYWHO SHOULD NOT USE A RAPID FAT LOSS APPROACH (CONTRAINDICATIONS)This is an updated look at a topic Lyle originally wrote about in 2005 and last published on in 2008 so after more than 20 years of digging into Rapid Fat Loss, I'm excited to share what he has and hasn't changed about this approach.Tune in now and get clarity on the most misunderstood fat loss method in the industry.WHERE TO CONNECT WITH ME:Follow Brandon on IG: https://www.instagram.com/brandondacruz_/For Info on Brandon's Coaching Services: https://form.jotform.com/bdacruzfitness/coachinginquiryEmail: Bdacruzfitness@gmail.comBrandon's Website: https://www.brandondacruzfit.com

IQBAR is offering our special podcast listeners 20% OFF all IQBAR products, plus get FREE shipping. To get your 20% off, text VANESSA to 64000. That's VANESSA to sixty-four thousand. Message and data rates may apply. See terms for details. This episode of the Optimal Protein Podcast takes a deep dive into the Protein-Sparing Modified Fast (PSMF) — a scientifically designed approach for rapid fat loss that prioritizes lean muscle preservation. Listeners will learn: What defines a PSMF and how it works in practice The latest research on fat loss outcomes and muscle retention How PSMF compares with ketogenic diets, VLCDs, and intermittent fasting Differences in results between men and women Short-term benefits and potential challenges with long-term use How to implement cycling strategies, refeed phases, and sustainable maintenance plans Evidence-based guidelines for safe and effective use Packed with research findings and practical insights, this episode provides a clear, evidence-based look at how PSMF can be used as a tool for body recomposition, fat loss, and long-term health. Connect with Vanessa on Instagram @ketogenicgirl Free High-Protein Keto Guide Get 20% off on the Tone LUX Crystal Red Light Therapy Mask or the Tone Device breath ketone analyzer at Ketogenicgirl.com with the code VANESSA Join the Community! Follow Vanessa on Instagram to see her meals, recipes, informative posts, and much more! Click here @ketogenicgirl Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast. Link to join the Facebook group for the podcast: The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.

You've seen the promotions – “Get a new Knee and walk the same day.” Sounds too good to be true – but is it? Let's learn the truth about what muscle sparing knee replacement really entails and who is truly a candidate for it.

In this episode of the NCS Podcast Masterclass series, hosts Jon Rosenberg, MD, and Stephan A. Mayer, MD, FCCM, FNCS, are joined by Carolina B. Maciel, MD, MSCR, and Katharina Busl, MD, MS, professors of neurology at the University of Florida. They explore the evolution of opioid-sparing pain management strategies in patients with subarachnoid hemorrhage and acute brain injury. The conversation highlights Dr. Maciel and Dr. Busl's work with sphenopalatine ganglion nerve blocks and the design of a phase 2 clinical trial investigating this novel technique. The guests also discuss the limitations of traditional analgesic options, the complexities of headache mechanisms in neurocritical care and how targeted interventions may improve outcomes and quality of life for patients in the neuro ICU. The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.

If you have had the privilege of ever seeing someone transform their physical appearance by doing a protein sparing modified fast, then you will be wondering, as I am. How can that be possible. I talk about why and what happens to those people.What if they were finally getting the amount of protein they required, or was it due to all the things they were no longer consuming that were bad for them and their metabolism? Kind of both ... but how is that.Facebook Group about Keto: https://www.facebook.com/groups/ketonaturopath/Website: https://ketonaturopath.com/Pinterest: https://www.pinterest.com/ketonaturopathFree Keto Food List: https://ketonaturopath.ac-page.com/keto-food-list-optinPSMF 30 day course: https://www.thebiointegrationcode.com/courses/PSMFChallengePodcast: https://www.buzzsprout.com/482971/episodesDry farm wineshttps://www.dryfarmwines.com/products/wine-membershipKeto mojohttps://shop.keto-mojo.com/?rfsn=3712430.393b9c&utm_source=refersion&utm_medium=affiliate&utm_campaign=3712430.393b9cYouTube channelhttps://www.youtube.com/channel/UCMeEev_sU0AGFYLYDjwccAw

LifeBlood: We talked about sparing children from divorce, the percentage of divorced couples with regret, the collective amnesia of the importance of commitment, the role entitlement plays in this process, and how to not start looking for the eject button from your marriage, with Pamela Henry, author and advocate for children of divorce.  Listen to learn why becoming desensitized may be why we find ourselves where we are! You can learn more about Pamela at Soul-Custody.com, and LinkedIn. Get your copy of Soul Custody here: https://amzn.to/4eWvP84  Thanks, as always for listening! If you got some value and enjoyed the show, please leave us a review here: ​​https://ratethispodcast.com/lifebloodpodcast You can learn more about us at LifeBlood.Live, Twitter, LinkedIn, Instagram, YouTube and Facebook or you'd like to be a guest on the show, contact us at contact@LifeBlood.Live.  Stay up to date by getting our monthly updates. Want to say “Thanks!” You can buy us a cup of coffee. https://www.buymeacoffee.com/lifeblood Copyright LifeBlood 2025.

D&P Highlight: Manhunt continues for man accused of killing four, sparing baby in Tennessee full 207 Mon, 04 Aug 2025 19:01:00 +0000 qjoMnT0EUnKwJu9IrrHtutTT6Xm9GqCq news The Dana & Parks Podcast news D&P Highlight: Manhunt continues for man accused of killing four, sparing baby in Tennessee You wanted it... Now here it is! Listen to each hour of the Dana & Parks Show whenever and wherever you want! © 2025 Audacy, Inc. News False h

Today's episode is going to focus on ligament reconstruction in skeletally immature patients – including various growth plate sparing ACL reconstruction techniques, MPFL reconstruction considerations and clinical outcomes.We are joined today by two outstanding guests! Dr. Mininder Kocher is a professor of orthopedic surgery at Harvard Medical School, Chief of Sports Medicine and Director of the Sports Medicine Fellowship at Boston Children's Hospital. He is the former President of PRISM and POSNA, and serves on the board of directors for AAOS and AOSSM.Dr. Lauren Redler is an assistant professor of orthopedic surgery at Columbia University Irving Medical Center and is actively involved in medical student, resident and fellow education at Columbia Ortho. She has published extensively on surgical treatment of ACL tears and patellar instability in pediatric patients, and is presenting her research on outcomes of MPFL reconstruction in skeletally immature patients at AOSSM this year!So, without further ado, let's get to the Exhibit Hall!

Rib-sparing DIEP flap refers to a technique used during Deep Inferior Epigastric Perforator (DIEP) flap breast reconstruction surgery where the surgeon preserves the rib and surrounding muscle when accessing the blood vessels that supply the flap.Quick Breakdown:    •    DIEP Flap Reconstruction:    •    Uses skin and fat from the lower abdomen to create a new breast after mastectomy.    •    Preserves the abdominal muscles (unlike TRAM flap).    •    Requires connection of the flap's blood vessels (deep inferior epigastric vessels) to chest vessels, usually the internal mammary vessels (IMVs).    •    Traditional DIEP:    •    Often involves removal of a portion of rib cartilage (typically the 2nd or 3rd rib) to reach the internal mammary vessels for microsurgical connection.    •    This can lead to post-op pain, risk of chest wall weakness, or delayed healing.    •    Rib-Sparing Technique:    •    Avoids rib removal by carefully dissecting around the rib or using intercostal spaces.    •    Benefits:    •    Less post-op pain.    •    Preserved chest wall integrity.    •    Potentially quicker recovery.    •    More cosmetic outcome (less chance of chest wall contour deformity).Clinical Note:    •    Rib-sparing is technically more challenging and requires a skilled microsurgeon.    •    Not all patients are candidates; it depends on anatomy, vessel quality, and other surgical considerations.Connect with Midwest Breast on Instagram: Instagram: Instagram: @MWBreastStay Connected with Dr. Deepa Halaharvi:TikTok: @breastdoctorInstagram: @drdhalaharviTBCP Instagram: @thebreastcancerpodcastWebsite: https://drdeepahalaharvi.com/YouTube: https://www.youtube.com/@deepahalaharvi5917Instagram: @thebreastcancerpodcast

This piece focuses on strategies for opioid-sparing anesthesia guided by the NOL Index, emphasizing the variability in patient responses to opioids. The importance of monitoring nociception, using advanced devices and techniques to customize opioid dosing, reduce side effects, and confirm the effectiveness of regional anesthesia. Our presenter shares personal experiences from their professional life and case studies, illustrating the benefits and challenges of implementing multimodal and opioid-free anesthesia approaches. The talk highlights the need for individualized treatment strategies in critical care and anesthesia. Presented by Esteban Salas Rezola, Specialist in Anaesthesiology, Resuscitation and Pain Therapy at Hospital General Alicante.

If your doctor is recommending that you get a mastectomy, you will likely have some choices about how the surgery is performed. Your breast cancer treatment, your body, your breast shape and your lifestyle affect not only your options, but also the pros and cons of your options. There's no one method that works best for everyone because each person is unique. Today we are going to be exploring one specific type of mastectomy – the nipple-sparing mastectomy. This is a skin-sparing mastectomy that leaves the nipple and areola intact and usually improves the overall look of the reconstructed breast. Joining us on the show today are two very special guests: Dr. Mara Piltin, a Breast and Melanoma Surgical Oncologist and Physician Assistant, Maddie Beiswanger, both from Mayo Clinic. They are going to tell us more about nipple-sparing mastectomy procedures, current research that is being conducted around the use of minimally invasive robotic surgery to assist in these procedures and the possible benefits that these innovations can provide. This episode of The Real Pink Podcast is brought to you by Intuitive Surgical. Intuitive is a global technology leader in minimally invasive care and the pioneer of robotic-assisted surgery. Intuitive has been advancing minimally invasive care since 1995 with the goal of helping physicians improve the lives of people around the world. You can learn more at www.Intuitive.com

Our biggest concern is knowing God. He reveals himself to us in our lives— always at the center—the sovereign ruler. Sparing, delivering, and carrying us throughout the traps and trials. Seating us at His table, no longer enemies, and rejoicing in the One who is the true bread of life.

In this week's episode of MedNews Week's Oncology Unplugged, host Chandler Park, MD, a medical oncologist at Norton Cancer Institute in Louisville, Kentucky, concluded a 3-part series with Vadim Koshkin, MD, an associate professor of medicine in the Division of Hematology and Oncology in the Department of Medicine at the University of California, San Francisco (UCSF) School of Medicine, as well as a genitourinary medical oncologist at the UCSF Helen Diller Comprehensive Cancer Center. In part 3 of this 3-part episode series, Drs Park and Koshkin explored the clinical implications of practice-changing data from the phase 3 NIAGARA trial (NCT03732677) of perioperative durvalumab plus neoadjuvant chemotherapy in patients with resectable bladder cancer and discussed how the evolving perioperative treatment paradigm may affect future treatment sequencing decisions for this population. Additional topics included ongoing research efforts focused on bladder-sparing strategies, the utility of circulating tumor DNA and advanced imaging to guide treatment intensity, and the role of biomarker-driven approaches to personalize therapy for patients with muscle-invasive disease.

ICYMI: Hour One of ‘Later, with Mo'Kelly' Presents – Thoughts on President Trump's global ‘Liberation Day' tariffs…PLUS – A look at some of the odd foods coming to the 2025 OC Fair, preparations for the 2025 Deltopia chaos coming to Santa Barbara AND who is to blame for the soaring gas prices in LA County – on KFI AM 640…Live everywhere on the iHeartRadio app

Sparing with world leaders, provoking trade wars, using the White House as a Tesla car showroom!? Alright, lets put a Common Folk perspective on some of this. So buckle up and Enjoy!

Welcome to cutting-edge approach to Breast Reconstruction: "The Nerve Sparing DIEP flap"A "Nerve sparing DIEP flap" refers to a surgical technique used in breast reconstruction where the surgeon carefully dissects and preserves the nerves that supply the rectus abdominis muscle when harvesting tissue from the lower abdomen using the deep inferior epigastric perforator (DIEP) flap, minimizing potential complications like abdominal weakness or bulging at the donor site by avoiding damage to these motor nerves; essentially, it prioritizes preserving the function of the abdominal muscles while taking the necessary tissue for breast reconstruction. Key points about nerve sparing DIEP flap:•Muscle preservation: Unlike older techniques like the TRAM flap, a DIEP flap aims to completely spare the rectus abdominis muscle, only taking the skin, fat, and blood vessels supplied by the perforating vessels from the deep inferior epigastric artery. •Nerve identification: During surgery, the surgeon carefully identifies and dissects around the nerves that innervate the rectus muscle to minimize their damage. •Benefits: By preserving the nerves, a nerve-sparing DIEP flap can help maintain abdominal wall strength, reduce the risk of hernias, and improve post-operative function and body contour. Connect with Midwest Breast on Instagram: Instagram: Instagram: @MWBreastStay Connected with Dr. Deepa Halaharvi:TikTok: @breastdoctorInstagram: @drdhalaharviTBCP Instagram: @thebreastcancerpodcastWebsite: https://drdeepahalaharvi.com/YouTube: https://www.youtube.com/@deepahalaharvi5917Instagram: @thebreastcancerpodcast

In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ K-Sparing Diuretics⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Renal section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

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