Podcasts about Aortic stenosis

In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.

In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.

In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Clonal Hematopoiesis Is Associated With Adverse Clinical Outcomes and Left Ventricular Remodeling in Aortic Stenosis

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Multiorgan Dysfunction and its Association With Congestion and Outcome in Aortic Stenosis Treated With TAVI

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826241296674

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826241296412

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826241296676

Read the article here: https://journals.sagepub.com/doi/full/10.1177/30494826241296668

Recent randomized trials, including EARLY TAVR, AVATAR, RECOVERY, and EVOLVED, suggest benefits of early aortic valve replacement (AVR) in asymptomatic severe aortic stenosis (AS). Early AVR reduces stroke, heart failure hospitalizations, and cardiovascular events, with a trend toward improved survival. The data support shifting from clinical surveillance to early intervention?

The EVOLVED trial investigated whether early aortic valve intervention could improve outcomes in asymptomatic patients with severe aortic stenosis and myocardial fibrosis. The randomized, multicenter study of 224 patients found no significant difference in all-cause mortality or unplanned aortic stenosis-related hospitalizations between early intervention and guideline-directed conservative management. However, early intervention was associated with lower rates of NYHA class II-IV symptoms and fewer unplanned hospitalizations. The trial highlights the potential symptomatic benefits of early intervention but underscores the need for further research to assess long-term outcomes.

The TCW Trial compared TAVI + FFR-guided PCI versus SAVR + CABG in patients with severe aortic stenosis and complex coronary artery disease. This multicenter, randomized controlled trial included 172 patients aged ≥70 years. At 1 year, the primary composite endpoint (death, MI, stroke, revascularization, valve reintervention, or major bleeding) was significantly lower in the TAVI + PCI group (4%) compared to SAVR + CABG (23%), meeting both noninferiority and superiority criteria. The study suggests TAVI + PCI as a safer, less invasive alternative with reduced mortality and bleeding risks in selected patients.

This episode covers paediatric aortic stenosis.Written notes can be found at https://zerotofinals.com/paediatrics/cardiology/paediatricaorticstenosis/Questions can be found at https://members.zerotofinals.com/Books can be found at https://zerotofinals.com/books/The audio in the episode was expertly edited by Harry Watchman.

EVOLVED: Early Intervention in Patients with Asymptomatic Severe Aortic Stenosis and Left Ventricular Myocardial Fibrosis

Dr. Trina Augustin, assistant professor of both anesthesiology and perioperative medicine as well as emergency medicine takes us on a deep dive into the care of persons with aortic stenosis. In this chapter, Alex and Venk learn about how to use ultrasound to diagnose AS, the keys to resuscitation, the pathophysiology of this condition, as well as the value of consultative services and the potential interventions that they may unlock for these patients. Kickoff season 4 with this in depth reminder that sometimes the heart has many hidden perils beyond ACS.  CONTACTS X - @AlwaysOnEM; @VenkBellamkonda YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch; @KatrinaJoyAugustin Email - AlwaysOnEM@gmail.com REFERENCES & LINKS Lichtenstein DA, Meziere GA. Relevance of Lung Ultrasound in the Diagnosis of Acute Respiratory Failure. Chest 2008; 134:117-125 Walsh MH, Smyth LM, Desy JR, Fischer EA, Goffi A, Li N, Lee M, St-Pierre J, Ma IWY. Lung Ultrasound: A Comparison of image interpretation accuracy between curvillinear and phased array transducers. Australia J Ultrasound Med, 26:150-156 Alzahrani H, Woo MY, Johnson C, Pageau P, Millington S, Thiruganasambandamoorthy V. Can severe aortic stenosis be identified by emergency physicians when interpreting a simplified two-view echocardiogram obtained by trained echocardiographers? Crit Ultrasound J. 2015 Apr 18;7:5. doi: 10.1186/s13089-015-0022-8. PMID: 25932319; PMCID: PMC4409610. Furukawa A, Abe Y, Morizane A, Miyaji T, Hosogi S, Ito H. Simple echocardiographic scoring in screening aortic stenosis with focused cardiac ultrasonography in the emergency department. J Cardiol. 2021 Jun;77(6):613-619. doi: 10.1016/j.jjcc.2020.12.006. Epub 2020 Dec 29. PMID: 33386216. Lin J, Drapkin J, Likourezos A, Giakoumatos E, Schachter M, Sarkis JP, Moskovits M, Haines L, Dickman E. Emergency physician bedside echocardiographic identification of left ventricular diastolic dysfunction. American Journal of Emergency medicine  Ehrman RR, Russell FM, Ansari AH, Margeta B, Clary JM, Christian E, Cosby KS, Bailitz J. Can emergency physicians diagnose and correctly classify diastolic dysfunction using bedside echocardiography? Am J Emerg Med. 2015 Sep;33(9):1178-83. doi: 10.1016/j.ajem.2015.05.013. Epub 2015 May 21. PMID: 26058890.2021;44:20-25 Del Rios M, Colla J, Kotini-Shah P, Briller J, Gerber B, Prendergast H. Emergency physician use of tissue Doppler bedside echocardiography in detecting diastolic dysfunction: an exploratory study. Crit Ultrasound J. 2018 Jan 25;10(1):4. doi: 10.1186/s13089-018-0084-5. PMID: 29372430; PMCID: PMC5785451. Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J, de Waha A, Richardt G, Hennersdorf M, Empen K, Fuernau G, Desch S, Eitel I, Hambrecht R, Lauer B, Böhm M, Ebelt H, Schneider S, Werdan K, Schuler G; Intraaortic Balloon Pump in cardiogenic shock II (IABP-SHOCK II) trial investigators. Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial. Lancet. 2013 Nov 16;382(9905):1638-45. doi: 10.1016/S0140-6736(13)61783-3. Epub 2013 Sep 3. PMID: 24011548. Aksoy O, Yousefzai R, Singh D, Agarwal S, O'Brien B, Griffin BP, Kapadia SR, Tuzcu ME, Penn MS, Nissen SE, Menon V. Cardiogenic shock in the setting of severe aortic stenosis: role of intra-aortic balloon pump support. Heart. 2011 May;97(10):838-43. doi: 10.1136/hrt.2010.206367. Epub 2010 Oct 20. PMID: 20962337. Karatolios K, Chatzis G, Luesebrink U, Markus B, Ahrens H, Tousoulis D, Schieffer B. Impella support following emergency percutaneous balloon aortic valvuloplasty in patients with severe aortic valve stenosis and cardiogenic shock. Hellenic J Cardiol. 2019 May-Jun;60(3):178-181. doi: 10.1016/j.hjc.2018.02.008. Epub 2018 Mar 21. PMID: 29571667. Gottlieb M, Long B, Koyfman A. Evaluation and Management of Aortic Stenosis for the Emergency Clinician: An Evidence-Based Review of the Literature. J Emerg Med. 2018 Jul;55(1):34-41. doi: 10.1016/j.jemermed.2018.01.026. Epub 2018 Mar 7. PMID: 29525246.  

Co-STAR: Colchicine in Patients with Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Double-Blind Randomized Controlled Trial

TAVR UNLOAD: Transcatheter Aortic Valve Replacement in Patients with Systolic Heart Failure and Moderate Aortic Stenosis

Commentary by Dr.  Jian'an Wang.

In this episode of Everyday Health Stories, Dr. Kota Reddy and Anna dive into the complexities of calcific aortic stenosis, a progressive heart condition that affects millions, particularly those over 65. They explore its causes, symptoms, and risk factors, while shedding light on the diagnostic tools and treatment options, including surgical aortic valve replacement and transcatheter aortic valve implantation. Discover the importance of early detection, regular monitoring, and lifestyle adjustments in managing this condition. Whether you're curious about heart health or seeking practical insights, this episode offers valuable information to keep your heart in check.

Calcific aortic stenosis affects approximately 12% of people >75 years in the US and worldwide leads to more than 100 000 deaths each year. Catherine M. Otto, MD, PhD, of the University of Washington School of Medicine, Seattle, discusses the symptoms, diagnosis, and treatment of aortic stenosis with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content: Calcific Aortic Stenosis

Author Nicolas M. Van Mieghem, MD, PhD, FACC, and JACC: Executive Associate Editor Aakriti Gupta, MD, FACC,  discuss the TAVR UNLOAD trial, which focused on patients with moderate aortic stenosis (AS) and reduced ejection fraction (HFrEF). The trial found no significant difference in the primary endpoint (composite of mortality, stroke, and hospitalizations) between the TAVR and clinical surveillance groups. However, patients who underwent TAVR showed a significant improvement in quality of life at one year. The conversation highlighted the need for individualized treatment approaches, emphasizing patient selection, while also considering trial limitations, including slow enrollment and study size.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on lipoprotein(a) levels in severe aortic stenosis referred for transcatheter aortic valve implantation compared to controls.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper about a novel echocardiographic parameter to confirm low-gradient aortic stenosis severity.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses results from the PROGRESSA Study recently published in an original research paper on sex-specific functional status decline and outcomes in mild-to-moderate aortic stenosis.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses insights from the PROGRESSA Study in a recently published original research paper on AI-enhanced prediction of aortic stenosis progression.

DISCLAMER >>>>>>    The Ditch Lab Coat podcast serves solely for general informational purposes and does not serve as a substitute for professional medical services such as medicine or nursing. It does not establish a doctor/patient relationship, and the use of information from the podcast or linked materials is at the user's own risk. The content does not aim to replace professional medical advice, diagnosis, or treatment, and users should promptly seek guidance from healthcare professionals for any medical conditions.   >>>>>> The expressed opinions belong solely to the hosts and guests, and they do not necessarily reflect the views or opinions of the Hospitals, Clinics, Universities, or any other organization associated with the host or guests.       Disclosures: Ditch The Lab Coat podcast is produced by (Podkind.co) and is independent of Dr. Bonta's teaching and research roles at McMaster University, Temerty Faculty of Medicine and Queens University. Welcome to "Ditch the Lab Coat," the podcast where we dive into pressing health issues with scientific skepticism and heartfelt curiosity. I'm your host, Dr. Mark Bonta, and in this episode we have a special guest, Dr. Spencer Nadolsky. Dr. Nadolsky is a board-certified obesity and lipid specialist known for his straightforward approach to fitness and health, and for pioneering obesity management via telemedicine. In this episode, we'll dive into various topics, including the intricacies of Lipoprotein(a) and its impact on cardiovascular health, the balance between lifestyle changes and pharmaceutical interventions, and the challenges of research funding in lifestyle modifications. We'll also explore Spencer's insights on effective weight loss strategies, sustainable diets, and his personal journey with health and fitness. So, whether you're here to glean some practical tips or to understand the latest in medical research, stay tuned—this is going to be an enlightening conversation.04:44 Sustainable weight loss requires satiating, nutritious food.08:55 Intermittent fasting, increased exercise caused weight loss.10:57 Dietary composition impacts health beyond weight loss.14:05 Appetite largely dictates body weight and thinness.17:09 Medication and bariatric surgery enhance weight loss results.20:55 Future obesity prevention: targeting genetic and socioeconomic risks.22:47 Medications reduce hypertension but overlook underlying causes.25:51 Drug trial: ~10% weight loss, possible cardiovascular benefits.29:32 Higher LDL and APOB increase long-term plaque risk.33:40 Advise family about LDL cholesterol management realistically.38:48 High school glucose test fueled sports nutrition interest.39:59 Anti-aging field's evolving, medication secondary uses explored.45:28 Biopsychosocial model emphasizes controllable and uncontrollable factors.47:31 Lifestyle changes are equally important as medications.49:49 Exciting times ahead; feedback appreciated. Stay tuned.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper about a clinical cohort study using an artificial intelligence algorithm for detection of severe aortic stenosis.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on machine learning prediction for prognosis of patients with aortic stenosis.

Order 'Build, Don't Talk' (in English) here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.eu/d/eCfijRu⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Order 'Build Don't Talk' (in Hindi) here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.eu/d/4wZISO0⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Disclaimer: This episode is intended solely for educational purposes and opinions shared by the guest are his personal views. We do not seek to defame or harm any person/brand/product mentioned in the episode. Our goal is to provide information to help audience make informed choices.

Balloon-Expandable Versus Self-Expanding Transcatheter Valves in Raphe-Type Bicuspid Aortic Stenosis

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on changes and prognostic implications of myocardial work in aortic stenosis subtypes undergoing transcatheter valve implantation

Percutaneous Versus Surgical Treatment for Patients with Aortic Stenosis and Coronary Disease

Ready to dig into the latest cardiology research? In less than 15 minutes, we'll give you the low-down on three new studies that'll help you in clinical practice. STUDY #1: First, we explore safety outcomes for carotid artery stenting and see how this could impact your clinical discussions and decision-making. And if you practice in the U.S., now that Medicare and Medicaid cover this procedure for a broader range of patients, this info will prove to be especially important.  Uchida, K, Sakakibara, F, Sakai, N, et al. 2024. Real-world outcomes of carotid artery stenting in symptomatic and asymptomatic patients with carotid artery stenosis. JACC Cardiovasc Interv. 9: 1160-1162. (https://doi.org/10.1016/j.jcin.2024.03.014) STUDY #2: Next, we tackle a common cardiology conundrum: how should we handle significant coronary artery disease lesions discovered incidentally in patients with severe aortic stenosis who are undergoing transcatheter aortic valve replacement? Is it better to treat these lesions beforehand, or is there a better strategy? We'll probe the debate, highlighting the potential implications of this new data. Colaiori, I, Paolucci, L, Mangiacapra, F, et al. 2024. Natural history of coronary atherosclerosis in patients with aortic stenosis undergoing transcatheter aortic valve replacement: The role of quantitative flow ratio. Circ Cardiovasc Interv. 0: e013705. (https://doi.org/10.1161/CIRCINTERVENTIONS.123.013705) STUDY #3: Lastly, we sip our way through the nuances of coffee consumption and its impact on blood pressure and cardiac arrhythmias. A new study lets us know whether our patients' daily caffeine fix can be left off the list of cardiac concerns. Trevano, F, Vela-Bernal, S, Facchetti, R, et al. 2024. Habitual coffee consumption and office, home, and ambulatory blood pressure: Results of a 10-year prospective study. J Hypertens. 6: 1094-1100. (https://doi.org/10.1097/HJH.0000000000003709) Join us to break down these studies, and elevate your cardiology knowledge! Learn more with these courses: Coronary Angiography Essentials (3 CME) Coronary Angiography Essentials Workshop (1 CME) Get a Basic or Pro account, or, get a Trial account. Show notes: Visit us at  https://www.medmastery.com/podcasts/cardiology-podcast.

Aortic Stenosis explained clearly, including  pathophysiology and causes. Also features the aortic stenosis murmur sound, and treatment including TAVI vs SAVR. Consider subscribing on YouTube (if you found any of the info useful!): https://www.youtube.com/channel/UCRks8wB6vgz0E7buP0L_5RQ?sub_confirmation=1Patreon: https://www.patreon.com/rhesusmedicineBuy Us A Coffee!: https://www.buymeacoffee.com/rhesusmedicineTimestamps:0:00 What is Aortic Stenosis? 0:51 Aortic Stenosis Pathophysiology2:16 Aortic Stenosis Causes3:39 Aortic Stenosis Symptoms5:04 Aortic Stenosis Murmur 6:46 Aortic Stenosis Diagnosis7:10 Aortic Stenosis Treatment - TAVI 08:06 Aortic Stenosis Treatment - SAVRHeart sounds by:Professional Skill Builder, Copyright 2005-2015 by The Regents of the University of Michigan (https://www.med.umich.edu/lrc/psb_open/html/repo/primer_heartsound/primer_heartsound.html)License: https://creativecommons.org/licenses/by-sa/4.0/ReferencesBMJ Best Practice (2024) - “Aortic Stenosis”. Available at https://bestpractice.bmj.com/topics/en-gb/325Guy P. Armstrong*, MD -* MSD Manual Pro (2023) - “Aortic Stenosis”. Available at https://www.msdmanuals.com/professional/cardiovascular-disorders/valvular-disorders/aortic-stenosisGuillaume Marquis-Gravel, MD, Msc - AHA Journals (2016) - “Medical Management of Aortic Stenosis”. Available at https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.023997Please remember this video and all content from Rhesus Medicine is meant for educational purposes only and should not be used as a guide to diagnose or to treat. Please consult a healthcare professional for medical advice. 

Anesthesia is critical to surgical procedures, ensuring patients are comfortable and pain-free during operations. However, administering anesthesia is not without risks, especially for patients with underlying health conditions like aortic stenosis. In this episode, we are joined by Dr. Paul Rollins, Oral Surgeon at Falls Oral Surgery & Dental Implant Center, to explore some of his anesthesia near misses with patients. Learn about the basics of aortic stenosis, what the symptoms are, and how to identify it before administering anesthesia. Discover how to differentiate between aortic stenosis and Still's murmur, why you need a high-quality stethoscope, and how to identify a diastolic murmur. We also delve into the process that follows after reliably identifying aortic stenosis, the pitfalls of relying completely on advisors for clearance, and the importance of maintaining a patient's blood pressure while avoiding hypertension during anesthesia. Gain insight into other issues to consider before administering general anesthesia, the importance of asking questions, and more. Join us as we learn about some of the ways anesthesia can go wrong and how to avoid them with Dr. Paul Rollins!Key Points From This Episode:Why case reviews are so valuable for preventing problems.First case: an older male who exhibited aortic stenosis before general anesthesia.Second case: an older male with hypertension who exhibited a clear aortic stenosis.Third case: an older male diagnosed with aortic stenosis but cleared for general anesthesia.Fourth case: an anxious older female who had an obvious red flag.Fifth case: an older female who misrepresented her medical history. Dr. Rollins' final takeaways and valuable advice for listeners!Quotes:“One the most frightening things about healthcare, what we do on a daily basis, and healthcare in general is we base so much of what we do on what the patient tells us about their history.” — Dr. Paul Rollins [0:04:00]“Once a patient becomes symptomatic with aortic stenosis, the mortality rate approaches 50% within two years without any intervention.” — Dr. Paul Rollins [0:07:14]“Sometimes [aortic stenosis] murmurs are so loud that you will hear it almost anywhere on the chest.” — Dr. Paul Rollins [0:18:51]“If you hear a diastolic murmur, don't move forward with the case. Get it diagnosed and figured out first.” — Dr. Paul Rollins [0:29:00]“Never do something that you are uncomfortable doing because a patient is trying to pressure you into doing it.” — Dr. Paul Rollins [0:32:18]Links Mentioned in Today's Episode:Dr. Paul Rollins — linkedin.com/in/paul-rollins-25248848Falls Oral Surgery & Dental Implant Center — fallsoralsurgery.comShōgun — imdb.com/title/tt2788316Narcos — imdb.com/title/tt2707408The Gentlemen — imdb.com/title/tt13210838The Little Book of Common Sense Investing — amazon.com/dp/1119404509Man's Search for Meaning — amazon.com/dp/1846042844/Everyday Oral Surgery Website — everydayoralsurgery.com Dr. Grant Stucki Email — grantstucki@gmail.comDr. Grant Stucki Phone — 720-441-6059

Today we discuss aortic stenosis, atrial fibrillation, and atrial flutter.  My special guests are Professor Stephen Worthley, an interventional cardiologist, and Associate Professor Hari Raju, a cardiac electrophysiologist.  Both are with Macquarie University Hospital, part of MQ Health which sponsored this podcast.  With MJA news and online editor, Sam Hunt. 27 mins.

Commentary by Dr. Candice Silversides

Commentary by Dr. Candice Silversides

Lifetime Strategy in the Management of Aortic Stenosis Guest: Mackram F. Eleid, M.D. and Kevin L. Greason, M.D. Hosts: Patricia A. Pellikka, M.D. This topic will discuss advances in the treatment of aortic stenosis, particularly with transcatheter aortic valve replacement. Strategies to manage aortic valve disease over a patient's lifespan will be discussed, including topics of valve in valve, choice of prosthesis type, and commissural alignment.   Topics Discussed: How has treatment of aortic stenosis changed in the last 10 years? What are some of the challenging decisions physicians and patients make when deciding about treatment of aortic stenosis? Explain the concept of commisural alignment - how important is it? What is the longevity of TAVR valves and what treatments are available if they fail?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.

Commentary by Dr. Candice Silversides

Commentary by Dr. Valentin Fuster

Commentary by Dr. Valentin Fuster

Do you know the role your heart valves play? There are doors that allow blood to flow from one side of the heart to the other. There are several types of heart valve disease but the most common is aortic stenosis (AS). Early diagnosis and treatment for AS is vitally important for long-term survival. In this podcast, learn more about stenosis, the signs and symptoms and how this heart disease is diagnosed and treated.

Aortic Stenosis

Aortic Stenosis 2 of 3

Aortic Stenosis 3 of 3

TSRA Journal Club - Lifetime Management Of Aortic Stenosis by TSRA

Who should be screened for lung cancer? Find out about this and more in today's PV Roundup podcast.

Stroke is a potentially devastating TAVR complication. In this episode, CardioNerds (Drs. Amit Goyal, Nikolaos Spilias, Ahmed Ghoneem, and Chelsea Amo-Tweneboah) discuss TAVR and stroke risk, stroke prevention strategies, and future directions with Dr. Samir Kapadia, Department chair and chief, Cardiovascular Medicine at Cleveland Clinic. They also discuss device innovation and randomized controlled trial implementation for testing device safety and efficacy. Audio editing by CardioNerds Academy Intern, Dr. Chelsea Amo Tweneboah. As an adjunct to this episode and for a deeper review of cerebral embolic protection devices, read “Cerebral Embolic Protection Devices: Current State of the Art” by Agrawal, Kapadia et al., in US Cardiology Review. CardioNerds Aortic Stenosis SeriesCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! References - TAVR and Stroke Leon MB, Smith CR, Mack M, et al. Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery. New England Journal of Medicine. 2010;363(17):1597-1607. Kapadia SR, Makkar R, Leon M, et al. Cerebral Embolic Protection during Transcatheter Aortic-Valve Replacement. New England Journal of Medicine. 2022;387(14):1253-1263. Kapadia SR, Kodali S, Makkar R, et al. Protection Against Cerebral Embolism During Transcatheter Aortic Valve Replacement. Journal of the American College of Cardiology. 2017;69(4):367-377. Khan MZ, Zahid S, Khan MU, et al. Use and outcomes of cerebral embolic protection for transcatheter aortic valve replacement: A US nationwide study. Catheter Cardiovasc Interv. 2021;98(5):959-968.