Podcasts about clinical value

Host: Jennifer Caudle, DO Guest: Victoria A. Statler, MD, MSc Test-confirmed influenza outcomes provide a specific measure of influenza vaccine effectiveness (VE) and has helped to illustrate the potential benefit of cell-based versus egg-based vaccines.1 So what data support improved VE from cell-based flu vaccines versus egg-based vaccines? To learn more, join Dr. Jennifer Caudle as she speaks with Dr. Victoria A. Statler, Associate Professor of Pediatrics at the University of Louisville and the Director of the Pediatric Transplant and Immunocompromised Host service at Norton Children's Hospital. Reference: Stein AN, Mills C, McGovern, et al. Superior effectiveness of cell-based versus egg-based quadrivalent influenza vaccines against test-confirmed influenza over three consecutive seasons in the United States. Paper presented at: The Ninth European Scientific Working Group Influenza (ESWI) Influenza Conference; September 17-20, 2023: Valencia, Spain. USA-QIVc-23-0119 01/24

Host: Jennifer Caudle, DO Guest: Victoria A. Statler, MD, MSc Test-confirmed influenza outcomes provide a specific measure of influenza vaccine effectiveness (VE) and has helped to illustrate the potential benefit of cell-based versus egg-based vaccines.1 So what data support improved VE from cell-based flu vaccines versus egg-based vaccines? To learn more, join Dr. Jennifer Caudle as she speaks with Dr. Victoria A. Statler, Associate Professor of Pediatrics at the University of Louisville and the Director of the Pediatric Transplant and Immunocompromised Host service at Norton Children's Hospital. Reference: Stein AN, Mills C, McGovern, et al. Superior effectiveness of cell-based versus egg-based quadrivalent influenza vaccines against test-confirmed influenza over three consecutive seasons in the United States. Paper presented at: The Ninth European Scientific Working Group Influenza (ESWI) Influenza Conference; September 17-20, 2023: Valencia, Spain. USA-QIVc-23-0119 01/24

Host: Jennifer Caudle, DO Guest: Victoria A. Statler, MD, MSc Test-confirmed influenza outcomes provide a specific measure of influenza vaccine effectiveness (VE) and has helped to illustrate the potential benefit of cell-based versus egg-based vaccines.1 So what data support improved VE from cell-based flu vaccines versus egg-based vaccines? To learn more, join Dr. Jennifer Caudle as she speaks with Dr. Victoria A. Statler, Associate Professor of Pediatrics at the University of Louisville and the Director of the Pediatric Transplant and Immunocompromised Host service at Norton Children's Hospital. Reference: Stein AN, Mills C, McGovern, et al. Superior effectiveness of cell-based versus egg-based quadrivalent influenza vaccines against test-confirmed influenza over three consecutive seasons in the United States. Paper presented at: The Ninth European Scientific Working Group Influenza (ESWI) Influenza Conference; September 17-20, 2023: Valencia, Spain. USA-QIVc-23-0119 01/24

This podcast was a conversation with Rob Corley, Chief Growth Officer, from Impensa Advisors. Rob has previously been a VP of Supply Chain Services and Analytics for major GPOs and has a vast wealth of savings knowledge and experience in advanced non-salary (supplies & services) expenses. Our goal was to share with you the true potential of looking beyond contract price and thinking outside the box but with your existing data sets in order to save as much as 7% to 15% of your total non-salary budget. We packed a lot of great information and even some benchmarks into this podcast. We hope you enjoy this episode!

As we begin a new year, it is good to take a step back and take a good look in the mirror at your value analysis and cost management programs. These are especially important right now in these tough economic times where your Chief Financial Officer is looking for every dollar of revenue and savings they can muster. Plus, it is just a good time to improve the things that need to be improved and make your value analysis program more efficient, time savvy, and get better results than you have in the past.

What is antimicrobial resistance and how is it impacting us and our health? For more information checkout: Discovery and preclinical development of new antibiotics (PMID: 24646092), Five barriers to addressing antimicrobial resistance (Author: Rohan Kocharekar), CDC: Antibiotic Rsistance Threats in the United States 2019, National Strategy for Combating Antibioticresistant Bacteria (Obama Administration), National Action Plan for Combating Antibiotic-Resistant Bacteria 2020-2025 (ASPE), United States National Actiona Plan (CDC), Enhancing US-Japan Cooperation to Combat Antimicrobial Resistance (PMID: 25470465), A View on 20 Years of Antimicrobial Resistance in Japan by Two National Surveillance Systems: The National Epidemiological Surveillance of Infectious Diseases and Japan Nosocomial Infections Surveillance (PMID: 34680770), Estimating the Economic and Clinical Value of Reducing Antimicrobial Resistance to Three Gram-negative Pathogens in Japan (PMID: 34703834), Strategy on Antiobiotic Resistance Switzerland (StAR), Epidemiological aspects of non-human antibiotic usage and resistance: implications for the control of antibiotic resistance in Ghana (PMID: 22413809), Occurrence of Antibiotics and Antibiotic-Resistant Bacteria in Landfill Sites in Kumasi, Ghana (Article ID: 6934507), Determinants of Inappropriate Antibiotics Use in Rural Central Ghana Using a Mixed Methods Approach (PMID: 32266200), Resistance to antimicrobial drugs in Ghana (PMID: 22259250), Scoping Report on Antimicrobial Resistance in India, India's National Action Plan for antimicrobial resistance – An overview of the context, status, and way ahead (PMID: 31334140), Antimicrobial resistance in the environment: The Indian scenario (PMID: 31219076).

Frontline clinicians and the patients they support cannot afford to encounter non-functional instrumentation and equipment in the surgical workflow. So how do your Sterile Processing and Operating Room teams ensure your surgical equipment and instruments are fully functional, safe and consistently perform at the highest level -- every surgery, every time? Joining us for the latest Beyond Clean Vendor Spotlight™ is Michael Matthews, MBA, CLSSGB, Director of Customer Training and Education at Agiliti, where he discusses the tremendous resources and creative partnerships available to clinicians to solve common process breakdowns within the OR and SPD. How can data transparency and repair reports lead to less preventable instrument damage? What tools are clinicians using to audit their processes and improve their quality? Tune in to learn more!   For more information about Agiliti, you can visit agilitihealth.com or follow them on Linkedin at linkedin.com/company/agilitihealth/   #AgilitiHealth #SurgicalInstruments #FlexibleScopes #InstrumentRepair #Education #SterileProcessing #OperatingRoom #Endoscopy

Drs Vallerie McLaughlin and Richard Channick discuss the diagnosis and treatment of chronic thromboembolic pulmonary hypertension. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/968550). The topics and discussions are planned, produced, and reviewed independently of advertiser. This podcast is intended only for US healthcare professionals. Resources Pulmonary Hypertension https://www.medscape.com/answers/303098-93380/what-is-pulmonary-hypertension Chronic Thromboembolic Pulmonary Hypertension (CTEPH) https://emedicine.medscape.com/article/2500057-overview Pulmonary Embolism https://emedicine.medscape.com/article/300901-overview Determinants of Diagnostic Delay in Chronic Thromboembolic Pulmonary Hypertension: Results From the European CTEPH Registry https://erj.ersjournals.com/content/52/6/1801687 Pulmonary Embolism Response Teams: Purpose, Evidence for Efficacy, and Future Research Directions https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611377 V/Q Scan https://www.medscape.com/answers/300901-8522/how-is-vq-scanning-used-for-the-diagnosis-of-pulmonary-embolism-pe Multidetector Computed Tomography for Acute Pulmonary Embolism https://www.nejm.org/doi/10.1056/NEJMoa052367 Pulmonary Thromboendarterectomy https://www.medscape.org/viewarticle/556058_4 Dynamic Risk Stratification of Patient Long-term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort https://pubmed.ncbi.nlm.nih.gov/27052413/ Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension https://err.ersjournals.com/content/26/143/160119 Balloon Pulmonary Angioplasty as a Treatment in Chronic Thromboembolic Pulmonary Hypertension: Past, Present, and Future https://pubmed.ncbi.nlm.nih.gov/32056029/ Pulmonary Arterial Hypertension Clinical Presentation https://emedicine.medscape.com/article/303098-clinical Riociguat https://reference.medscape.com/drug/adempas-riociguat-999863 Long-term Clinical Value and Outcome of Riociguat in Chronic Thromboembolic Pulmonary Hypertension https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396196/ Riociguat Prescribing Information https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/204819s006lbl.pdf

Medtronic has weathered the test of time as an innovative company. In this episode we have Mr. Carlton Weatherby with us. Carlton is an industry veteran and has a terrific background at Medtronic. He has experience in their business development group, and we discuss the intricacies of mergers & acquisitions. Carlton walks us through the path to the mass market and scalability. He doesn't stop there we get into the true clinical value proposition and so much more. Gurus this is an action-packed episode and you will love what Carlton brings as our Guru!

Guest: John C. Byrd, MD For patients with chronic lymphocytic leukemia, molecular analysis can provide critical information. Dr. John C. Byrd discusses the importance of IGHV and TP53 sequencing and the clinical value they provide.

With Roberto Lang & Karima Addetia, University of Chicago Medicine, Chicago - USA Link to European Heart Journal - Cardiovascular Imaging paper Link to European Heart Journal - Cardiovascular Imaging editorial

After graduating from the University of Alberta with a Bachelor of Science and M.D in 1990, Dr. Logsetty obtained his Diploma in Clinical Epidemiology from the University of Toronto in 1996 garnering many awards along the way. Dr Logsetty completed the Surgical-Scientist Program at University of Toronto in 1994-1996. He continued his training in fellowships in Acute Burn Care & Reconstructive Surgery at Ross Tilley Burn Centre in Wellesley Hospital in Toronto, Ontario (1996-1998) and in Critical Care of Burns at Harborview Medical Centre in Seattle, Washington (1998-1999). He was appointed to the position of Associate Director of the Firefighters Burn Treatment Unit at the University of Alberta Hospital in 1999. He was also the Director of Resident Research for the General Surgery Department at the University of Alberta Hospital from 2005 to 2007. During his time at the University of Alberta Hospital he was promoted from Assistant Professor to Associate Professor. In 2007 he was recruited by the University of Manitoba and the Health Sciences Centre to take on the position of Director of the brand new Burn Unit located at Health Sciences Centre in Winnipeg. He remains an Associate Professor of Surgery at the University of Manitoba and was appointed the Director of Research for the Section of Plastic Surgery. In this episode, we get all fired up about burn care. We talk about training pathways for burn surgeons, burn resuscitation, operative management of burns, and finally about Dr. Logsetty’s innovative research into burn wound management. Links: 1. Dr. Logsetty’s nature review on burns: https://pubmed.ncbi.nlm.nih.gov/32054846/ 2. Clinical Value of Debriding Enzymes as an Adjunct to Standard Early Surgical Excision in Human Burns; A Systematic Review: https://academic.oup.com/jbcr/advance-article-abstract/doi/10.1093/jbcr/iraa074/5840378?redirectedFrom=fulltext 3. Simple Derivation of the Initial Fluid Rate for the Resuscitation of Severely Burned Adult Combat Casualties: In Silico Validation of the Rule of 10. https://pubmed.ncbi.nlm.nih.gov/20622619/ 4. Mental health outcomes of burn: A longitudinal population-based study of adults hospitalized for burns. https://europepmc.org/article/med/27049068 5. Bacteria-Responsive Single and Core-Shell Nanofibrous Membranes Based on Polycaprolactone/Poly(ethylene Succinate) for On-Demand Release of Biocides. https://pubs.acs.org/doi/10.1021/acsomega.8b03137

Host: Jennifer Caudle, DO Guest: Liza Kunz, MD, FACOG Amid the expanding noninvasive prenatal testing (NIPT) options, Dr. Liza Kunz joins Dr. Jennifer Caudle to discuss what differentiates genome-wide NIPT from other options, how it works, and its limitations and potential benefits. US MSA Educational Program

Host: Jennifer Caudle, DO Guest: Liza Kunz, MD, FACOG Amid the expanding noninvasive prenatal testing (NIPT) options, Dr. Liza Kunz joins Dr. Jennifer Caudle to discuss what differentiates genome-wide NIPT from other options, how it works, and its limitations and potential benefits. US MSA Educational Program

Host: Jennifer Caudle, DO Guest: Liza Kunz, MD, FACOG Amid the expanding noninvasive prenatal testing (NIPT) options, Dr. Liza Kunz joins Dr. Jennifer Caudle to discuss what differentiates genome-wide NIPT from other options, how it works, and its limitations and potential benefits. US MSA Educational Program

Host: Jennifer Caudle, DO Guest: Liza Kunz, MD, FACOG Amid the expanding noninvasive prenatal testing (NIPT) options, Dr. Liza Kunz joins Dr. Jennifer Caudle to discuss what differentiates genome-wide NIPT from other options, how it works, and its limitations and potential benefits. US MSA Educational Program

Host: Jennifer Caudle, DO Guest: Liza Kunz, MD, FACOG Amid the expanding noninvasive prenatal testing (NIPT) options, Dr. Liza Kunz joins Dr. Jennifer Caudle to discuss what differentiates genome-wide NIPT from other options, how it works, and its limitations and potential benefits. US MSA Educational Program

Training and activity is your no1 option when recovering from low back pain.  This episode introduces two of the most important exercises for building up strength within your lower back and practice movement control.   Strength Training for People with Low Back Pain  Always check with your medical professional if it is save for you to exercise! This exercises are not a substitute for individual medical treatment but aim to complement and support your recovery process. Find all videos for this episode on: http://mybackrecovery.com/resources.page video episode 07   The exercises we are going to explore on this episode build up on your basic movement control skills and are both: challenging your movement control skills helping you building up strength and strength endurance within your back muscles  If you have listened to episode 06 you already have come to learn that clinical guidelines recomend therapeutic exercise and activity with strong supporting evidence for the management of chronic low back pain. A recent review concluded that: "The hypothesis of specific lumbar extensor deconditioning as being a causal factor in LBP is presently well supported." meaning: weak back muscles could cause LBP.1 It further says: "It is by no means the only causative factor and further research should more rigorously test this hypothesis (...) however specific exercise may be a worthwhile preventative and rehabilitative approach."   In this episode i will share some of my most favorite exercises for building up strength within your back extensor muscles and practice movement control. These classis exercises will give you more options with your training, and will take your training to the next level.   Training introduced on 'my Back recovery' so far: Episode 03: Easy and back specific circle training with save loading profiles in terms of exercising. A first step in starting to work on strength and strength endurance as well as stability. Also a great way of improving blood flow in your muscles. video   Episode 05: Movement control exercises - basic skills for exercising - moving your pelvis/hip influences the posture of your lower back - being able of keeping a neutral position during certain exercises. video   As you learned the basics for movement control (ep 5) and started to get familiar with a back specific circle training (ep 3) it´s time for you to take the next step!   'Good Morning' & Squat Video The good morning and the squat are static exercises for your back. This means no movement in the back while you are doing the exercises. They are more difficult to perform than the exercise-set from episode 03.  It really pays of focusing on doing the good morning and the squat with correct posture! Once you got this you can do most of other exercises in a correct way and will have more options to adjust exercises to your own needs. Remember to always adjust your exercises to your individual situation so that you are able to perform pain free and without aggravation of your symptoms. Good Morning The 'good morning' is great for building strength2 and movement control. Actually the 'good morning' is also used as a part of a validated test series used to detect impaired movement control within people with LBP.3 It works the gluteus, hamstrings and lower back.   Basically the 'good morning' is about bending forward with a straight (neutral) back. Remember the last movement control exercise from episode 05: sitting and rocking forward and backward while keeping a moderate arch of your lower back with no movement in the back. The good morning exercise is the same in a standing position.   Stay upright, bend your knees slightly. This will help you doing the movement from your hips (because your hamstrings are not that much stretched when you are bending your knees). Bend forward while you are keeping a straight back (remember straight means slightly curved, we wanna see a moderate arch (like a weightlifter) at the lower back, if your back seems to be flat, it is already flexed, we want to trigger those back extensor muscles and keep a neutral position thats why we need that arch!  This exercise should be pain free! So if you are doing it correctly and start to experience pain while leaning forward, remember the golden training principles. Adjust the exercise. Don´t go so far. Maybe you can do it leaning fwd 45 degrees out from the vertical position and will feel fine, and pain starts only if you go further. So respect your pain and adjust the exercise. Most people who hadn´t done this kind of exercise will find it difficult to perform in the beginning. Here is how i teach the 'good morning' to my clients:   First i start with all the exercises from episode 05. If you havent mastered these go back and work on them until you feel comfortable with them. video - basic movement control skills episode 05 Most of the time the problem is that people don´t know how to keep good posture in their lower back. The movement you need to do is 'push your bum out while leaning forward'. This will result in hip flexion and back extension and result in a moderate arch in your lower back. Again some people could experience discomfort when arching to much. So experiment and find a position that is comfortable and pain free. The basic movement control skills from episode 05 will help you with that!   Than i let my clients sit on a high chair or at the edge of a table with their feet standing on the ground. Now it´s like a mix of the rocking forward and backward exercise we did at the end of episode 05, and the good morning. It´s a bit easier than in the standing position. If you feel fine proceed to the standing position.   It´s natural that when leaning forward to much, you will loose the arch in your lower back. So just go as far as it is pain free and you can keep correct posture. Even when you are doing only a small movement like 10-20 degrees forward bending you still train your muscles and start to practice movement control.   One thing i experience quite often when people are doing the good morning is that they are squatting simultaneously. Although there is nothing harmful with this i suggest making two exercises out of it and not mixing the good morning and the squat. With this strategy you will gain better movement control and have more variability in you training options. So keep your knees slightly bent but try not to squat while leaning forward, and check this in a mirror from your side! You have to actively work for not bending your knees while leaning forward.   Squats Absolut classics! Squats also work your back extensor muscles. Squatting is a typical everyday activity. Besides working all major muscle groups in your body and helping you stay fit, good form/posture with squatting will help you becoming more aware of your posture in everyday activities. The squat is almost the same as the good morning but with knee-movement and less dynamic leaning forward and backward.  Starting position: Standing upright, having your weight evenly distributed to both of your feet, leaning a bit forward and squatting down. Again keep that lower back arched when leaning forward. If you can control your back already let´s check your knees. When squatting down look to your knees and feet: have your toes pointing straight forward and try to keep your medial border of your kneecap outside of your big toe. This will result in proper hip knee ankle alignment and less stress and strain on your knee. 4, 5 You can do the squat in a narrow stance or a wide stance. But keep your feet pointing forward and mind your knee position!     find more information at www.mybackrecovery.com   Literatur:  Steele J, Bruce-Low S, Smith D. A reappraisal of the deconditioning hypothesis in low back pain: review of evidence from a triumvirate of research methods on specific lumbar extensor deconditioning. Curr Med Res Opin. 2014;30(January):1-47. doi:10.1185/03007995.2013.875465. Steele J, Bruce-Low S, Smith D. A Review of the Clinical Value of Isolated Lumbar Extension Resistance Training for Chronic Low Back Pain. PM R. 2014;(OCTOBER 2014):1-18. doi:10.1016/j.pmrj.2014.10.009. Luomajoki H, Kool J, de Bruin ED, Airaksinen O. Movement control tests of the low back; evaluation of the difference between patients with low back pain and healthy controls. BMC Musculoskelet Disord. 2008;9(Mc):170. doi:10.1186/1471-2474-9-170. Lee TQ, Morris G, Csintalan RP. The influence of tibial and femoral rotation on patellofemoral contact area and pressure. J Orthop Sports Phys Ther. 2003;33(11):686-693. doi:10.2519/jospt.2003.33.11.686. Koga H, Nakamae A, Shima Y, et al. Mechanisms for noncontact anterior cruciate ligament injuries: knee joint kinematics in 10 injury situations from female team handball and basketball. Am J Sports Med. 2010;38(11):2218-2225. doi:10.1177/0363546510373570.      

Commentary by Dr. Valentin Fuster

An Interview with Ernest W. Johnson, MD, author of "Clinical Value of Motor Nerve Conduction Velocity Determination," an article appearing in JAMA 1960;172:2030-2035. Interviewed by Lawrence H. Phillips, II, MD and Gary Goldberg, MD. The participants in this Podcast had nothing to disclose.

An Interview with Ernest W. Johnson, MD, author of "Clinical Value of Motor Nerve Conduction Velocity Determination," an article appearing in JAMA 1960;172:2030-2035. Interviewed by Lawrence H. Phillips, II, MD and Gary Goldberg, MD. The participants in this Podcast had nothing to disclose.

Clinical Value of Motor Nerve Conduction Velocity Determination by Ernest W. Johnson, MD

Find Out About the New Clinical and Scientific Research on the Safety and Benefit of Intravenous Vitamin C Used Alone, and with Chemo and Radiation Therapy Kirk Hamilton interviews Jeanne Drisko, MD, MD director of the Program in Integrative Medicine at the University of Kansas Medical Center. Dr Drisko teaches medical students, practices integrative medicine, and conducts clinical research at the University on the use of intravenous vitamin C in cancer, the safety of bioidentical hormones and trials to assess chelation therapy efficacy in cardiovascular disease treatment. She is a graduate of the University of Kansas Medical School and board certified in diagnostic radiology. Dr. Drisko's was previously interviewed by Kirk Hamilton on July 24, 2009 on "Cancer and I.V. Vitamin C - Safety, Clinical Value and Protocol?" and Integrative Medicine - What Is It and Why Does Medicine Need It? Download or Open:

The Safe and Effective Use of Intravenous Vitamin C With Chemo And Radiation Therapy Kirk Hamilton interviews Jeanne Drisko, MD director of the Program in Integrative Medicine at the University of Kansas Medical Center. Dr Drisko teaches medical students, practices integrative medicine, and conducts clinical research at the University on the use of intravenous vitamin C in cancer, the safety of bioidentical hormones and trials to assess chelation therapy efficacy in cardiovascular disease treatment. She is a graduate of the University of Kansas Medical School and board certified in diagnostic radiology. Download or Open:

An Interview with Ernest W. Johnson, MD, author of "Clinical Value of Motor Nerve Conduction Velocity Determination," an article appearing in JAMA 1960;172:2030-2035. Interviewed by Lawrence H. Phillips, II, MD and Gary Goldberg, MD. The participants in this Podcast had nothing to disclose.

An Interview with Ernest W. Johnson, MD, author of "Clinical Value of Motor Nerve Conduction Velocity Determination," an article appearing in JAMA 1960;172:2030-2035. Interviewed by Lawrence H. Phillips, II, MD and Gary Goldberg, MD. The participants in this Podcast had nothing to disclose.

Clinical Value of Motor Nerve Conduction Velocity Determination by Ernest W. Johnson, MD

Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis and 101 first-degree relatives of patients with ulcerative colitis, 50 patients with infectious enterocolitis and 100 healthy controls were tested for ASCA employing the ELISA technique. When compared with the healthy controls (p < 0.0001) and patients with infectious enterocolitis (p < 0.0001) the prevalence of ASCA was significantly increased in patients with Crohn's disease and their first-degree relatives (p < 0.01). Further significant differences concerning the frequency of ASCA within the different groups of our study population were not observed. In particular, ASCA were not found in increased prevalence in infectious enterocolitis. These observations are compatible with a role of ASCA as a marker of genetic predisposition to Crohn's disease. Copyright (C) 2002 S. Karger AG, Basel.