Focus on Women's and Men’s Health

Host: Ayse Tuba Kendi, MD Guest: A. Oliver Sartor, MD Prostate-specific membrane antigen (PSMA) is highly expressed on prostate cancer (PC) cells and can be detected in tumors using positron emission tomography imaging. Even though clinical features predict different stages of PC progression, the application of imaging to guide treatment is still evolving but gaining substantial evidence for the targeting of PSMA. With clinical research shifting paradigms for the treatment of metastatic castration-resistant prostate cancer (mCRPC), novel treatment options require adoption and effective application into clinical practice. PSMA has become an appealing target for diagnostic agents for imaging and therapeutic agents to treat mCRPC. Radionuclide emitters are being used for both cell surface expression of PSMA and the tumor microenvironment, and research has proven the therapeutic efficacy of PSMA-directed radioligand therapy (RLT). In this educational activity, two experts will examine the role and rationale for PSMA targeted therapies and diagnostics—jointly known as theragnostics—as a revolutionary new approach to treating patients with advanced prostate cancer and will evaluate clinical trial data for PSMA-targeted RLT.

Host: Paul Doghramji, MD Guest: Megan Arnot Menopause is an inevitable transition in every woman’s life, but what if engaging in a basic physiological need like sex could delay its onset? Researching this potential connection is Megan Arnot, a Ph.D. candidate in the Department of Anthropology at the University College London. As the lead author of the study, she walks us through her findings and the range of factors they investigated, like the type of sexual activity and whether or not women lived with a partner.

Host: Jennifer Caudle, DO Guest: Frank LoVecchio, DO, MPH, FACEP The cold weather inevitably brings an increase in flu cases each year, and joining Dr. Jennifer Caudle to unveil the high-risk populations—and how we can treat the members of those vulnerable populations who do get the flu—is Dr. Frank LoVecchio, Professor of Emergency Medicine at the University of Arizona and Principal Investigator for the Infectious Disease Network.

Host: Jennifer Caudle, DO Guest: Frank LoVecchio, DO, MPH, FACEP Guest: Casey Lafferty, DO Due to the high prevalence of influenza each winter, knowing how to treat those most at risk is essential. That's why Dr. Frank LoVecchio and Dr. Casey Lafferty are here to discuss the 2019-2020 flu season activity and patterns, along with preventive tips and treatment options you can provide to your patients.

Host: Jennifer Caudle, DO Guest: Liza Kunz, MD, FACOG Amid the expanding noninvasive prenatal testing (NIPT) options, Dr. Liza Kunz joins Dr. Jennifer Caudle to discuss what differentiates genome-wide NIPT from other options, how it works, and its limitations and potential benefits. US MSA Educational Program

Guest: Sheryl A. Kingsberg, PhD Guest: Brooke M. Faught, DNP, WHNP-BC,NCMP, IF Guest: Risa Kagan, MD, FACOG, CCD, NCMP Guest: James A. Simon, MD, CCD, NCMP, IF, FACOG An average of 37.5 million menopausal women in the US between the ages of 45 and 64 experience symptoms such as hot flashes and joint pain, but there are other symptoms that we rarely talk about: symptoms like vaginal dryness and dyspareunia. Featuring a patient and a panel of experts, this discussion reviews strategies that can be used to help patients feel comfortable in bringing up their struggles with menopause along with how we can help relieve women from their pain. ©2019 NP-INR-US-00214 09/19

Host: Amy Mackey, MD Guest: Maria Trent, MD, MPH, FAAP, FSAHM Even though molecular assays are quickly becoming the standard of care for the diagnosis of Mycoplasma genitalium and other infectious conditions, there’s still much more to be shared and learned about how to rapidly identify this infection. And here to start that discussion is Dr. Maria Trent, Professor of Pediatrics in the Division of General Pediatrics and Adolescent Medicine at Johns Hopkins School of Medicine. Click here to learn more about other women's health programs in this special series.

Host: Mario R. Nacinovich, Jr., MSc Guest: Kara Rood, MD A recent study following 346 pregnant patients found that 63 percent of the women were admitted into the hospital for uncertain diagnosis or delivery—all because preeclampsia has many of the same symptoms of other diseases. The good news, however, is that there’s a new test currently underway that could make the diagnosis and treatment of preeclampsia easier in order to prevent potentially dangerous outcomes for the mother and baby, as OB/GYN Dr. Kara Rood explains.

Host: Keith Isaacson, MD Guest: Robert K. Zurawin, MD This activity will discuss approaches that enable physicians to perform hysteroscopic surgery more safely and effectively by focusing on best practices, overcoming operative difficulties, and the inclusion of pharmacologic agents that improve visualization, reduce vascularity, and lower the possibility of hyponatremia.

Host: Robert K. Zurawin, MD Guest: Malcolm G. Munro, MD This activity will discuss the numerous elements that make up the updated diagnostic and treatment algorithm to manage abnormal uterine bleeding, including using a minimally invasive surgical approach, having a better understanding of the broad umbrella of bleeding that occurs outside of normal cyclic menstruation, performing proper patient workups, and more.

Host: Brian P. McDonough, MD, FAAFP Human papillomavirus (HPV) infection remains one of the most common sexually transmitted infections in both females and males, with about 9 in 10 people contracting HPV at some point in their lives. Host Dr. Brian McDonough is joined by Samantha Gottlieb, medical anthropologist and author of Not Quite a Cancer Vaccine: Selling HPV and Cervical Cancer. They explore the history of Gardasil, a vaccine developed for HPV but marketed primarily as a cervical cancer vaccine, which became embroiled in sociopolitical debates about adolescent sexuality and pediatric vaccinations. The two discuss these precedents alongside current controversies, such as whether vaccinating both males and females will induce herd immunity, and if the benefits outweigh the risks.

Host: Brian P. McDonough, MD, FAAFP Human papillomavirus (HPV) infection remains one of the most common sexually transmitted infections in both females and males, with about 9 in 10 people contracting HPV at some point in their lives. Host Dr. Brian McDonough is joined by Samantha Gottlieb, medical anthropologist and author of Not Quite a Cancer Vaccine: Selling HPV and Cervical Cancer. They explore the history of Gardasil, a vaccine developed for HPV but marketed primarily as a cervical cancer vaccine, which became embroiled in sociopolitical debates about adolescent sexuality and pediatric vaccinations. The two discuss these precedents alongside current controversies, such as whether vaccinating both males and females will induce herd immunity, and if the benefits outweigh the risks.

Host: Matt Rosenberg, MD Guest: Aiden Harrington, ANP, CNM Current CDC Treatment Guidelines include transgender men and women as special populations. These guidelines recommend risk assessment based on current anatomy and sexual behaviors and screening for asymptomatic STIs based on the patient's history and sexual practices. At a recent live event recorded in Chicago, moderator Dr. Matt T. Rosenberg welcomes Aiden Harrington, ANP, CNM from Howard Brown Health in Chicago, Illinois. Topics covered include health risks in the LGBTQ community, STI screening and treatment, and how to discuss sexuality with your patients.

Guest: Sheryl A. Kingsberg, PhD Dr. Sheryl Kingsberg demonstrates counseling strategies clinicians can use with their patient when discussing dyspareunia in post-menopausal women. Dr. Sheryl Kingsberg is Chief of the Division of Behavioral Medicine in the Department of OB/GYN at University Hospitals Cleveland Medical Center and Professor of Reproductive Biology and Psychiatry at Case Western Reserve University School of Medicine in Cleveland, Ohio.

Guest: David J. Portman, MD Dr. David J. Portman demonstrates how clinicians can begin the conversation of dyspareunia with patients, as well as how to discuss the available treatment options for managing this condition in post-menopausal women. Dr. Portman is Director Emeritus at Columbus Center for Women’s Health Research; and, Adjunct Instructor of Obstetrics and Gynecology at The Ohio State University, Columbus, OH.

Host: Renée Simone Yolanda Allen, MD, MHSc., FACOG Guest: Heidi Faith Doulas have become an integral part of the obstetrics field. In recent years, a new, specialized type of doula, called the bereavement doula, has emerged. But what roles and duties are performed by this care provider? Host Dr. Renee Allen speaks with Heidi Faith, Founder, President and CEO of StillBirthDay, a highly specialized doula program. The two talk about the unique care roles a bereavement doula can play in the labor and delivery of stillborn babies.

Host: Brian P. McDonough, MD, FAAFP It's widely known that genetics, family history, race, and other factors all play important roles in cancer risk. But what kinds of roles do they play, specifically, and how can we leverage these understandings into better primary care? Dr. Brian McDonough is joined by Dr. Maureen Murphy, research scientist at the Wistar Institute at the University of Pennsylvania. Dr. Murphy has spent the past twenty years studying how genes affect breast cancer risk in women, particularly for African American populations. She discusses her findings on the discovery of p53 protein variants and how this advances the role for precision medicine in treating breast cancer.

Host: Brian P. McDonough, MD, FAAFP It's widely known that genetics, family history, race, and other factors all play important roles in cancer risk. But what kinds of roles do they play, specifically, and how can we leverage these understandings into better primary care? Dr. Brian McDonough is joined by Dr. Maureen Murphy, research scientist at the Wistar Institute at the University of Pennsylvania. Dr. Murphy has spent the past twenty years studying how genes affect breast cancer risk in women, particularly for African American populations. She discusses her findings on the discovery of p53 protein variants and how this advances the role for precision medicine in treating breast cancer.

FDA medical oncologists discuss the agency’s March 2017 approval of niraparib for the maintenance treatment of patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy. Released May 18, 2017

FDA medical oncologists discuss the agency’s March 2017 approval of niraparib for the maintenance treatment of patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy. Released May 18, 2017

Host: Maurice Pickard, MD Guest: Peter Dawson, MD In the male-dominated world of medicine, she dared to step forward and fight for fairness—graduating from Johns Hopkins Medical School with honors in the year 1900. But for physician Dorothy Reed Mendenhall, MD, the battle for equality was just beginning. In the name of improving the standards of care for women and infants, she faced the scorn of prejudiced doctors in an establishment marked by its unwillingness to change. Still, through the Gilded Age, two World Wars, and beyond, she kept up her fight—in the process, discovering new breakthroughs and saving lives, all while outperforming many of her male peers. Dorothy in a Man’s World is an inside look at the life and career of Dr. Mendenhall, documented by physician and pathologist Dr. Peter Dawson. This biographical tribute to one of medicine’s great female pioneers showcases the struggles women faced to make a name for themselves in the world of health care—in addition to the drastic improvements which have been made in the specific area of care for women and their infants. Dr. Dawson sits down with host Dr. Maurice Pickard as they explore Dr. Mendenhall's extraordinary life.

Host: Matt Birnholz, MD Guest: Ari Brooks, MD Guest: Brian Englander, MD Host Dr. Matt Birnholz is joined by Dr. Ari Brooks, Director of Endocrine and Oncology Surgery and Director of the Integrated Breast Center at Pennsylvania Hospital, and Dr. Brian Englander, Clinical Assistant Professor and Chair of the Department of Radiology at Pennsylvania Hospital. Drs. Brooks and Englander discuss the hot topics within breast cancer innovations. They touch upon the increase in involvement of genetics and genomic research that is impacting breast cancer treatment options, new breast imaging modalities, and continuity of care.

Host: Matt Birnholz, MD Guest: Robert H. Debbs, DO Joining Dr. Matt Birnholz to discuss counseling methods for patients who are trying to conceive is Dr. Robert Debbs, Director of the Pennsylvania Hospital Maternal Fetal Medicine Network in New Jersey and Clinical Professor of Obstetrics and Gynecology at Penn Medicine. Dr. Debbs will discuss pre-conceptual counseling on a range of topics such as obesity, congenital heart disease, depression, and conceiving after a miscarriage.

Host: Matt Birnholz, MD Guest: Paris D. Butler, MD, MPH Host Dr. Matt Birnholz welcomes Dr. Paris D. Butler, who will be discussing breast reduction surgery for women who suffer from chronic back pain and breast cancer patients undergoing reconstructive surgery following a diagnosis. Dr. Butler will go into detail about the pros and cons of taking an immediate versus a delayed reconstruction approach and the various techniques associated.

Host: Renée Simone Yolanda Allen, MD, MHSc., FACOG Guest: Carmen Brown, MD What does it take to pick up your practice and move to a foreign country? And what can be gained and lost in translation? Host Dr. Renee Allen chats with Dr. Carmen Brown,a board-certified OB/GYN practicing in New Zealand, about her experiences and perspectives transitioning a clinical practice and family home to another continent.

Host: Ana Maria Rosario Guest: Martin R. Chavez, MD, FACOG From the Women's Health Annual Visit in Chicago, host Ana Maria Rosario talks with Dr. Martin Chavez, the Director of Maternal Fetal Medicine and Fetal Surgery Program at Winthrop University Hospital, about the maternal-fetal effects of the Zika virus outbreak.

Host: Jennifer Caudle, DO Joining Dr. Jennifer Caudle to share insights about fibroid treatment updates and counseling methods is Dr. Jessica Shepherd, Assistant Professor of OB/GYN and Director of Minimally Invasive Gynecology at the University of Illinois in Chicago. Dr. Shepherd is the founder of HerViewpoint.com, an online forum for women designed to discuss all those women's health topics that are difficult to raise in doctors' offices.

Host: Alan S. Brown, MD, FNLA Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Robert Kloner, Vice President of Translation at Huntington Medical Research Institutes and Professor of Medicine in the Cardiovascular Division of Keck School of Medicine at the University of Southern California. Dr. Kloner discusses the cardiovascular risk factors associated with erectile dysfunction, safety and efficacy of erectile disfunction drugs, and benefits vs risks of supplementing with testosterone.

Host: Patrice L Basanta-Henry, MD, MHSc, FACOG Approximately just 0.5% of all births occur before the third trimester of pregnancy, yet these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. Care for infants born at the threshold of viability, less than 24 weeks of gestation and with body weights less than 1000 grams, poses many difficult clinical, social, and ethical questions among clinicians and families. Host Dr. Patrice Basanta-Henry speaks with guest Dr. Fyama Wenner, a maternal-fetal medicine specialist at Atlanta Maternal Fetal Medicine, about special care considerations for extremely preterm infants, as well as effective counseling strategies for families.

Host: Ana Maria Rosario Guest: Anita L. Nelson, MD Joining host Ana Maria Rosario at the Women's Health Annual Visit in Deerborn, MI, is Dr. Anita Nelson, professor emeritus at UCLA and professor and chair of OB/GYN at Western University in California. The two discuss patient barriers to accessing IUDs and implants in a rapidly growing contraceptive market.

Host: Brian P. McDonough, MD, FAAFP In a survey released by the American Academy of Family Physicians (AAFP), nearly half of men reported that their health was "good" or "excellent." This marked a dramatic increase in health perceptions from men over the past decade, despite the fact that more men now live with chronic conditions such as hypertension and diabetes than ever before. What does this discrepancy between perceptions and realities tell us about the state of health care for men in America? Joining Dr. Brian McDonough to discuss special considerations and primary care priorities for men is Dr. John Meigs, practicing generalist and President-Elect of the AAFP.

Host: Brian P. McDonough, MD, FAAFP Egg freezing, also known as oocyte cryopreservation, has gained rapid popularity as patient populations have broadened. Once intended almost exclusively for cancer patients undergoing aggressive chemotherapy treatments, more and more healthy women are choosing this resource to expand their reproductive options later in life. Dr. Lisa Ashe, internist and medical director for Be Well Medical Group in Alexandria, VA, speaks with Dr. Brian McDonough about her personal experience with egg freezing from three simultaneous vantage points: physician, patient, and minister.

Host: Maurice Pickard, MD STDs are widespread in all walks of life, regardless of gender, race, social status, or education. Seduced into complacency by the notion that "it can't happen to me" many sexually active teens and young adults are stunned when they are diagnosed with an STD. In Seductive Delusions: How Everyday People Catch STDs, author and physician Dr. Jill Grimes reveals the truths about sexually transmitted diseases through narrated accounts of young men and women, their exam room conversations with doctors, and both the physical symptoms and the emotional reactions that can accompany infection.

Host: Michael Krychman, MD Feminine hygiene, though an important part of daily life, is rarely discussed openly,not even in clinical settings. Host Dr. Michael Krychman sits down with Dr Alyssa Dweck, practicing gynecologist in New York and Assistant Clinical Professor at Mt. Sinai School of Medicine. They give essential tips for clinicians on how to talk to patients about feminine hygiene.

Host: Brian P. McDonough, MD, FAAFP Guest: Charles N. Walker, MD Dr. Charles Walker, Assistant Professor of Surgery in the Department of Urology at Yale University School of Medicine, shares clinical insights about penile prostheses, such as inflatable versus malleable devices, used as surgical gold standards to treat erectile dysfunction.

Host: Michael Krychman, MD The primary purpose of contraception is to separate sex from procreation. However, sexual function is rarely addressed or considered in the context of making contraceptive choices. Dr. Michael Krychman speaks with Dr. Rachel Perry, Assistant Professor of OB/GYN at the University of California-Irvine, about the various complex sexual health impacts of oral contraceptives, IUDs, condoms, and permanent sterilization procedures.

Host: Jennifer Caudle, DO There are many widely circulated myths regarding breast cancer, such as: Beliefs that this disease affects women only. Fears that mammograms can cause cancers to spread. Assumptions that most patients with breast cancer have family histories positive for this disease. Host Jennifer Caudle talks with guest Dr. Monique Gary, a fellowship-trained breast surgical oncologist at Grand View Health in Sellersville, Pennsylvania. Together, they dispel myths about breast cancer and talk about what patients can expect during a surgical oncologist appointment.

Host: Alan S. Brown, MD, FNLA Guest: Robert Wild, MD, MPH, D.Phil. Recorded live at the recent Annual National Lipid Association meeting, Dr. Alan Brown welcomes Dr. Robert Wild to discuss types of dyslipidemia that clinicans may see in women of child bearing age, particularly those using hormonal contraception. The two discuss ways for clinicians to trace the source of dyslipidemia in these women, from primary to secondary causes, and how this knowledge can guide future contraception choices. Dr. Robert Wild is Professor of OB/GYN and Adjunct Professor in Biostatistics and Epidemiology at the University of Oklahoma. He is also Adjunct Professor in Epidemiology at the University of Pittsburgh, and Adjunct Professor of Nutrition at Oklahoma State University.

Host: Shira Johnson, MD Guest: Charles N. Walker, MD Dr. Shira Johnson speaks with Dr. Charles Walker, Assistant Professor of Surgery in the Department of Urology at Yale University School of Medicine. The two focus on erectile dysfunction as a common complication for patients dealing with diabetes and heart disease, and ways that clinicians can help patients manage this problem through lifestyle modifications. Dr. Walker also introduces emerging pathophysiological understandings of ED as a potential predictor of diabetes.

Host: Michael Krychman, MD Ovarian cancer is among the most highly prevalent and deadly cancers in existence, and in the struggle to care for patients and protect their quality of life, clinical standards in diagnostic screening and treatment protocols must change frequently. Joining host Dr. Michael Krychman to discuss advances in treatment and prevention of ovarian cancer, with special focus on sexual health priorities, is guest Dr. Leslie Randall. Dr. Randall is Associate Professor of Obstetrics and Gynecology at the University of California-Irvine, and also Director of UC’s gynecologic oncology fellowship program.

Host: Renée Simone Yolanda Allen, MD, MHSc., FACOG Babies born before 37 weeks gestation face many challenges in their first weeks of life. For premature babies to thrive in the NICU, the American Academy of Pediatrics recommends all preterm babies weighing less than 1500 grams be fed human milk. However, this recommendation creates a dilemma for mothers who are unable to supply their own breast milk and must therefore turn to donation programs to feed their babies. Dr. Renee Allen chats with Scott Elster, CEO of Prolacta Bioscience, about the goals of breast milk donor programs to improve health outcomes for critically ill preemies, while also reducing NICU costs.

Host: Michael Krychman, MD Women who experience low libido often feel embarrassed, lonely, and unsure where to turn or with whom to confide. Left unaddressed, this issue can have devastating effects on relationships. Dr. Michael Krychman sits down with Amanda Parrish, nationally recognized patient advocate for women's sexual health, to talk about hypoactive sexual desire disorder (HSDD) and the need for clinicians to foster open conversations with patients about low libido.