Podcasts about Pulmonary embolism

Podcast summary of articles from the April 2025 edition of the Journal of Emergency Medicine from the American Academy of Emergency Medicine.  Topics include ECGs in cardiac arrest, strep toxic shock syndrome, diabetic ketoacidosis, chest pain work ups, exertional heat stroke, and pulmonary embolism controversies.  Guest speaker is Dr. Matthew Carvey.

There are many nuances in the management of patients with pulmonary embolism in cardiac arrest, peri-arrest or simply in shock: We need to optimize oxygenation and airway management, hemodynamic support, acid/base management, thrombolysis and/or catheter-directed therapies that Anton dives into with guest experts Dr. Lauren Westafer, Dr. Bourke Tillmann and Dr. Justin Morgenstern... EM Cases is proudly FOAMEd - Please consider a donation: https://emergencymedicinecases.com/donation/

CardioNerds Critical Care Cardiology Council members Dr. Gurleen Kaur and Dr. Katie Vanchiere meet with Dr. Yash Patel, Dr. Akanksha, and Dr. Mohammed El Nayir from Trinity Health Ann Arbor. They discuss a case of pulmonary air embolism, RV failure, and cardiac arrest secondary to an ocular venous air embolism. Expert insights provided by Dr. Tanmay Swadia. Audio editing by CardioNerds Academy intern, Grace Qiu. A 36-year-old man with a history of multiple ocular surgeries, including a complex retinal detachment repair, suffered a post-vitrectomy collapse at home. He was found hypoxic, tachycardic, and hypotensive, later diagnosed with a pulmonary embolism from ocular venous air embolism leading to severe right heart failure. Despite a mild embolic burden, the cardiovascular response was profound, requiring advanced hemodynamic support, including an Impella RP device (Abiomed, Inc.). Multidisciplinary management, including fluid optimization, vasopressors and mechanical support to facilitate recovery. This case underscores the need for early recognition and individualized intervention in cases of ocular venous air embolism. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls- Clear Vision, Clouded Heart: Ocular Venous Air Embolism with Pulmonary Air Embolism, RV Failure, and Cardiac Arrest Hypoxia, hypotension and tachycardia in a patient following ocular instrumentation are classic findings suggestive of pulmonary embolism from possible air embolism. The diagnosis of RV failure is based on clinical presentation, echocardiographic findings (such as McConnell's sign), and invasive hemodynamic assessment via right heart catheterization. Mechanical circulatory support can be considered as a temporary measure for patients with refractory RV failure. Central Figure: Approach to Pulmonary Embolism with Acute RV Failure Notes - Clear Vision, Clouded Heart: Ocular Venous Air Embolism with Pulmonary Air Embolism, RV Failure, and Cardiac Arrest 1. What is an Ocular Venous Air Embolism (VAE), and how can it be managed in critically ill patients? An Ocular Venous Air Embolism is defined as the entry of air into the systemic venous circulation through the ocular venous circulation, often during vitrectomy procedures. Early diagnosis is key to preventing cardiovascular collapse in cases of Ocular Venous Air Embolism (VAE).  The goal is to stop further air entry. This can be done by covering the surgical site with saline-soaked dressings and checking for air entry points. Adjusting the operating table can help, especially with a reverse Trendelenburg position for lower-body procedures. The moment VAE is suspected, discontinue nitrous oxide and switch to 100% oxygen. This helps with oxygenation, speeds up nitrogen elimination, and shrinks air bubbles. Hyperbaric Oxygen Therapy can reduce bubble size and improve oxygenation, especially in cases of cerebral air embolism, when administered within 6 hours of the incident. Though delayed hyperbaric oxygen therapy can still offer benefits, the evidence is mixed. VAE increases right heart strain, so inotropic agents like dobutamine can help boost cardiac output, while norepinephrine supports ventricular function and systemic vascular resistance, but this may also worsen pulmonary resistance.  Aspiration of air via multi-orifice or Swan-Ganz catheters has limited success, with success rates ranging from 6% to 16%. In contrast, the Bunegin-Albin catheter has shown more promise, with a 30-60% success rate. Catheterization for acute VAE-induced hemodynamic compromise is controversial, and there's insufficient evidence to support its ...

Evaluation Of Long-term Key Outcomes And Safety In Pulmonary Embolism: The EKOS-PE Study

Dr. Allison Greco, pulmonary and critical care specialist at Bellevue Hospital, sits down with Dr. Emily Gutowski and discusses the initial presentation, workup, and management of a patient with a pulmonary embolism. They go through diagnostic modalities, scoring systems, and the various treatment options for patients depending on their risk profile. They discuss provoked vs. unprovoked PEs, and recommendations for longer term anticoagulation.

Deputy Editor of The Lancet Respiratory Medicine Ari Colosio discusses the critical findings of a new epidemiological study on pulmonary embolism in children and adolescents with Simon Wolf from the University Hospital of Zurich. This episode delves into the prevalence, risk factors, and clinical implications of this rare but serious condition, highlighting the need for increased awareness and further research.Read the full article:https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00412-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanresContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

How do you predict which intermediate-risk patients will suddenly deteriorate? What role do risk scores, biomarkers, imaging, and hemodynamics play in decision-making? Should these patients receive anticoagulation alone, or is thrombolysis warranted? When should you consider catheter-directed or surgical interventions? This podcast focuses us to think critically about risk stratification, early interventions and escalation in care in PE. We include an algorithm in the show notes. Not all patients fit neatly into classification boxes, making clinical judgment crucial. Join Dr. Lauren Westafer, Dr. Justin Morgenstern, Dr. Bourke Tillman and Anton as they explore the key decision points, pitfalls, and lifesaving strategies for managing intermediate-risk PE in the ED...

For this episode we are joined by EBM guru, Dr. Brian Locke, who deftly breaks down all of our statistics questions. Is half dose DOAC as good as full dose DOAC for preventing VTE, and does it reduce bleeding risk? Can procalcitonin reduce duration of antibiotics for infections without compromising mortality rates? Can LLMs like GPT-4 help physicians manage patients better? Can reinforcement learning models predict when to start vasopressin in patients with septic shock? What is the risk of resuming anticoagulation in patients with atrial fibrillation and prior intracerebral hemorrhage? Is high flow nasal cannula as good as non-invasive ventilation for different types of respiratory failure? We answer all these questions and more!Half Dose DOAC for Long Term VTE Prevention (RENOVE)Biomarker-Guided Antibiotic Duration (ADAPT-Sepsis)GPT-4 Assistance for Physician PerformanceOptimal Vasopressin Initiation for Septic Shock (OVISS)DOACs for A fib after ICH (PRESTIGE-AF)High Flow Nasal Cannula vs NIV for Respiratory Failure (RENOVATE)Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R

Failure rate of D-dimer testing in patients with high clinical probability of pulmonary embolism: Ancillary analysis of three European studies by SAEM

Failure rate of D-dimer testing in patients with high clinical probability of pulmonary embolism: Ancillary analysis of three European studies by SAEM

Blood clots can be life-threatening, but understanding their causes and treatments can save lives. In Part 2 of our Hematology Series, Dr. Andrew Jenzer, DDS, dives deep into thrombosis, breaking down the three key contributing factors and the most common hypercoagulable conditions. We carefully dissect the pathophysiology of pulmonary embolisms, the most important guidelines to know and follow, the difference between provoked and unprovoked hypercoagulable conditions, and everything you need to know about the perioperative management of antithrombotic therapies. To close, Dr. Jenzer highlights the critical risk factors of preoperative anticoagulation and key takeaways from our conversation that should never be forgotten. If you're a healthcare professional or simply someone who values life-saving knowledge, this episode is packed with insights you won't want to miss. Tune in to sharpen your expertise and improve patient outcomes!Key Points From This Episode:Three contributors to thrombosis and the most common hypercoagulable conditions.Unpacking the pathophysiology of pulmonary embolisms.Wells' Criteria, CHEST, and other crucial guidelines to follow. The difference between provoked and unprovoked hypercoagulable conditions.  Anticoagulation therapies and important surgical considerations.Risk factors associated with the perioperative management of antithrombotic therapy. Recapping the key takeaways from today's conversation. Links Mentioned in Today's Episode:Dr. Andrew Jenzer Email — andrew.jenzer@gmail.com Dr. Andrew Jenzer | Duke Surgery — https://surgery.duke.edu/profile/andrew-clark-jenzer  ACOMS | Annual Winter Meeting — https://www.acoms.org/Events/Winter-Meeting/About Wells' Criteria for Pulmonary Embolism — https://www.mdcalc.com/calc/115/wells-criteria-pulmonary-embolism Wells' Criteria for DVT — https://www.mdcalc.com/calc/362/wells-criteria-dvt  American College of Chest Physicians — https://www.chestnet.org/  ‘Perioperative Management of Antithrombotic Therapy' — https://www.chestnet.org/guidelines-and-topic-collections/guidelines/pulmonary-vascular/perioperative-management-of-antithrombotic-therapy  ‘Perioperative Management of Patients with Atrial Fibrillation Receiving a Direct Oral Anticoagulant' — https://pubmed.ncbi.nlm.nih.gov/31380891/  ‘Perioperative Optimization and Management of the Oral and Maxillofacial Surgical Patient' — https://pubmed.ncbi.nlm.nih.gov/38103577/ Everyday Oral Surgery Website — https://www.everydayoralsurgery.com/ Everyday Oral Surgery on Instagram — https://www.instagram.com/everydayoralsurgery/ Everyday Oral Surgery on Facebook — https://www.facebook.com/EverydayOralSurgery/Dr. Grant Stucki Email — grantstucki@gmail.comDr. Grant Stucki Phone — 720-441-6059

Loren Ridinger changed the face of the beauty and e-commerce industries alongside her partner and husband, JR. Loren and JR went from $25 weeks to a billion dollar company! Two years ago, Loren faced her darkest day and biggest challenge yet after suddenly losing the love of her life from a Pulmonary Embolism. We tap into her new book, “Scrambled or Sunny Side Up?” and talk and love, loss and what's next for the distinguished entrepreneur.Loren's New Book!https://a.co/d/469DrocYouTubehttps://www.youtube.com/@HerestolifepodcastInstagramhttps://www.instagram.com/nickbarrotta https://www.instagram.com/lorenridingerhttps://www.instagram.com/herestolife.podApple Podcastshttps://podcasts.apple.com/us/podcast/heres-to-life-podcast/id1727965819

Venous Thromboembolism (VTE) is a condition where blood clots form in a blood vessel. As serious as heart attacks and strokes, VTE is the most common cause of preventable death in hospitalized patients. Interventional Radiologist Scott Perrin, MD, discusses the dangers of the disease and what can be done to treat deep vein thrombosis (DVT) and pulmonary embolism (PE).You can also watch the video recording on our Vimeo channel here.For more health tips & news you can use from experts you trust, sign up for Sarasota Memorial's monthly digital newsletter, Healthe-Matters.

Podcast summary of articles from the December 2024 edition of the Journal of Emergency Medicine from the American Academy of Emergency Medicine.  Topics include pulmonary embolism in COVID19 patients, intracranial bleeding, diltiazem in patients with heart failure, vital sign abnormalities, naloxone from the ED, and an interesting case report.  Guest speaker is Dr. Kinda Sweidan.

PEERLESS: Large-Bore Mechanical Thrombectomy vs Catheter-directed Thrombolysis for Treatment of Intermediate-Risk Pulmonary Embolism

Tune in now as the expert faculty dives into how the AlphaVac System is transforming pulmonary embolism treatment. In this podcast, they highlight key insights from the APEX-AV trial, explore real-world applications, and discuss the future of PE management. Don't miss this insightful discussion on bridging clinical trials to real-world impact!

This recording features audio versions of January 2025 Journal of Vascular and Interventional Radiology (JVIR) abstracts:Effectiveness of Track Cauterization in Reduction of Adverse Events for Lung Microwave Ablation ReadSelective Lymphatic Duct Embolization for Treatment of Thoracic Lymphatic Flow Disorders in Children: Technical Aspects and Comparison with Thoracic Duct Embolization ReadA Comparison of Postprocedural Hemoglobin in Catheter-Directed Thrombolysis versus Large-Bore Aspiration Thrombectomy for Acute Pulmonary Embolism ReadClinical Outcomes following Invasive Treatment of Femoropopliteal Artery Disease: A Retrospective Single-Center Cohort Study ReadOutcomes of Endovascular Treatment for Infectious Thoracic Aortic Diseases ReadThe Influence of Preablation Embolization Particle Size on the Size of the Microwave Ablation Zone in a Porcine Orthotopic Renal Tumor Model ReadJVIR and SIR thank all those who helped record this episode. To sign up to help with future episodes, please contact our outreach coordinator at millennie.chen.jvir@gmail.com.  Host:Manbir Singh Sandhu, University of California Riverside School of MedicineAudio editor:Manbir Singh Sandhu, University of California Riverside School of MedicineOutreach coordinator:Millennie Chen, University of California Riverside School of MedicineAbstract readers:Maximillion Hayama, Duke University School of MedicineSonya Choe, University of California Riverside School of MedicineSiddak Dhaliwal, University of Missouri School of MedicineAkumbir Singh Grewal, St. George's University School of MedicineBryan Torres, University of California Riverside School of MedicineJason Hoang, The Ohio State College of MedicineSIR thanks BD for its generous support of the Kinked Wire.Contact us with your ideas and questions, or read more about about interventional radiology in IR Quarterly magazine or SIR's Patient Center.(c) Society of Interventional Radiology.Support the show

A pulmonary embolism is a condition in which vessels in the lungs are blocked by a thrombus or other material that has traveled from somewhere else in the body. This is usually a result of a venous thromboembolism, but can also be due to amniotic fluid, air or fat embolus, or tumor material in patients with cancer. A key thing to understand about pulmonary embolism is that the airway is not occluded. In pulmonary embolism, one or more blood vessels are occluded. What this means is that blood coming from the right side of the heart isn't able to pass freely through the pulmonary vasculature to participate in gas exchange, which negatively affects perfusion. In this episode you'll learn: Pulmonary embolism pathophysiology Which of your patients are at highest risk for having a PE Common signs and symptoms of PE Priority nursing assessments Tests utilized to evaluate or diagnose PE Treatments for PE, including pharmacological and surgical And more! Hit play on this episode so you can understand how to recognize PE quickly so your patient can have their best chance at recovery. ___________________ Full Transcript - Read the article and view references FREE CLASS - If all you've heard are nursing school horror stories, then you need this class! Join me in this on-demand session where I dispel all those nursing school myths and show you that YES...you can thrive in nursing school without it taking over your life! Med Surg Solution - Are you looking for a more effective way to learn Med Surg? Enroll in Med Surg Solution and get lessons on 57 key topics and out-of-this-world study guides.  Straight A Nursing App - Study on-the-go with the Straight A Nursing app! Review more than 5,000 flashcards covering a wide range of subjects including Fundamentals, Pediatrics, Med Surg, Mental Health, Maternal Newborn, and more! Available for free in the Apple App Store and Google Play Store. LATTE Method Template - Download the free LATTE Method Template so you can streamline how you study and focus on what a nurse needs to know.  20 Secrets of Successful Nursing Students – Learn key strategies that will help you be a successful nursing student with this FREE guide!

Hear from the experts about the transformative benefits of the PE Center of Excellence (PE CoE) Accreditation Program. This session highlights how this innovative program can elevate your institution's standard of care for Pulmonary Embolism. Tune in to discover the blueprint for driving excellence in PE care.

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Dyspnea After Pulmonary Embolism: Optimal Medical Therapy in Peripheral Vascular Disease   Guest: Stan Henkin, M.D. Host: Malcolm R. Bell, M.D.   Historically, majority of clinical and research focus has been on acute management of pulmonary embolism (PE). However, long-standing functional impairment after PE is common, occurring in up to 50% of individuals with history of PE. This is termed post-PE syndrome – an underrecognized, underdiagnosed, and undertreated entity. In this podcast, experts discuss epidemiology, pathophysiology, diagnosis, and treatment of post-PE syndrome.   Topics Discussed: What is Post-PE syndrome? How common is it? What is your suggested work-up of patient who presents with dyspnea after PE? When should a patient be referred to a tertiary/expert center?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.  

On this week's release, Cyrus and Nick revisit one of their favorite topics: Pulmonary Embolism! In this episode - a follow up to our two-parter from season 1 - we sit down with Dr. Rick Channick of UCLA to talk about his approach to PE management with a focus on catheter directed therapies & PE response teams. This episode is packed full of expert insights and practical clinical pearls. Give it a listen and let us know what you think!Risk Stratification MethodologiesWhat is the landscape of risk stratification in Pulmonary Embolism (PE)?Broadly, what interventions does each risk category group warrant?Rule of Thumb: The greater the risk to the patient, the more likely aggressive interventions will be considered.Most patients with PE are low risk:Typically treated with systemic anticoagulationExcellent prognosis High risk PE patients typically have hemodynamic involvement and can present in shock requiring emergent management :No contraindications + shock due to PE systemic thrombolysisAbsolute contraindications:Prior history of ICHKnown cerebrovascular lesionKnown malignant intracranial neoplasmNon-acute ischemic stroke, within the last 3 monthsSuspect aortic dissectionIntermediate risk patients:Management options exist and are tailored to each specific patient.Most, but not all, patients with PE deemed to be at intermediate risk will do well with systemic anticoagulation.Some patients are good candidates for catheter directed therapies such as thrombectomy or thrombolysis.Who? We don't really know with a high degree of certainty. Considerations should be made for those with numerous risk factors for poor PE-related outcomes OR those with significant cardiopulmonary reserve / excellent functional status who theoretically could benefit from more brisk reversal of their acute pulmonary hypertension.See more in depth show notes at criticalcaretime.com Hosted on Acast. See acast.com/privacy for more information.

In this insightful episode of JACC, Dr. Valentin Fuster summarizes groundbreaking international clinical practice guidelines for acute pulmonary embolism, authored by Dr. Marco Suin and colleagues. The discussion delves into key aspects such as diagnosis, risk stratification, immediate anticoagulation, and advanced therapies, highlighting the challenges and recommendations that can ultimately guide clinicians in managing this critical condition.

Suzanne and Stephanie review another maternal death situation and discuss what they think happened. Listen and decide what you think it was.The experts at Clinical Concepts in Obstetrics pool their decades of experience caring for critically ill pregnant women to discuss the challenges encountered in caring for these vulnerable women. Dr Stephanie Martin is the Medical Director for Clinical Concepts in Obstetrics and a Maternal Fetal Medicine specialist with expertise in critical care obstetrics. Suzanne McMurtry Baird, DNP, RN is the Nursing Director for Clinical Concepts in Obstetrics with many years of experience caring for critically ill pregnant women. Julie Arafeh, RN, MS is the Simulation Director for Clinical Concepts in Obstetrics and a leading expert in simulation.Follow us: Instagram: https://www.instagram.comDr Martin's LinkedIn: http://linkedin.com/in/stephanie-martin-65b07112aCCOB LinkedIn: https://www.linkedin.com/company/clinical-concepts-in-obstetrics/Twitter/X: https://twitter.com/OBCriticalCareCCOB Facebook: https://www.facebook.com/clinicalconceptsinobstetricsDr Martin's Facebook: https://www.facebook.com/profile.php?id=100024366859192

Interventional Management of Acute Pulmonary Embolism   Guest: Arashk Motiei, M.D. Hosts: Sharonne Hayes, M.D.   We will discuss the can temporary interventional management of patients with massive acute pulmonary embolism and intermediate high-risk acute pulmonary embolism.   Topics Discussed: Who are the patients with pulmonary embolism who need to be considered for interventional treatment? What do we know about risk assessment in patients with intermediate high-risk pulmonary embolism?  What are the types of interventional treatments that are currently available? Systemic thrombolysis is often used for the management of acute pulmonary embolism.  Is there any role for this with the availability of interventional approaches?   Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices. LinkedIn: Mayo Clinic Cardiovascular Services Cardiovascular Education App: The Mayo Clinic Cardiovascular CME App is an innovative educational platform that features cardiology-focused continuing medical education wherever and whenever you need it. Use this app to access other free content and browse upcoming courses. Download it for free in Apple or Google stores today! No CME credit offered for this episode. Podcast episode transcript found here.  

Host Samantha Gambles Farr, MSN, AG-ACNP, FNP-C, RNFA, is joined by Roman Melamed, MD, to discuss the comparative effectiveness of reduced-dose versus full-dose alteplase for acute pulmonary embolism, focusing on patient outcomes and complications. They will highlight study findings on significant improvements in hemodynamic and respiratory parameters in both groups, with a lower rate of hemorrhagic complications in the reduced-dose group (Melamed R, et al. Crit Care Med. 2024;52:729-742). Dr. Melamed is a critical care intensivist and director of the Pulmonary Embolism Program at Abbott Northwestern Hospital in Minneapolis, Minnesota, USA, and an adjunct associate professor at the University of Minnesota.

It's been a long time, but we are back!Apologies on the audio quality from Dr. Jenkins. Apparently he was recording from inside a cardboard box.Today we talk about important, practice changing studies in internal medicine from the last several months. What's the best anticoagulant in patients with cirrhosis and atrial fibrillation? Why do doctors use so much unfractionated heparin for acute PE? Should we still be using beta blockers in patients with acute MI? Does finerenone improve outcomes in HFpEF? Is continuous infusion of antibiotics better than intermittent? And will the cefepime vs piperacillin-tazobactam battle ever end?Apixaban, Rivaroxaban and Warfarin in Cirrhosis for AFAnticoagulation Trends for Acute PEBeta Blockers for Acute MI with Normal EF Finerenone for HFpEF FINEARTS-HFContinuous vs Intermittent Infusion of Beta-Lactams BLING IIIProlonged vs Intermittent Infusions of Beta-Lactams Meta-analysisPiperacillin-Tazobactam vs Cefepime for SepsisRecurrent SBP in Patients on Secondary Prophylaxis

This recording features audio versions of October 2024 Journal of Vascular and Interventional Radiology (JVIR) abstracts:Mortality, Safety, and Effectiveness of Paclitaxel-Containing Balloons and Stents in the Femoropopliteal Artery: Systematic Review and Meta-Analysis of Randomized Controlled Trials since 2018 ReadEffect of Filtered Blood Return on Outcomes of Pulmonary Aspiration Thrombectomy ReadThe Predictive Value of Qanadli and Miller Index Scores in Patients with Intermediate-High–Risk and High-Risk Pulmonary Emboli Undergoing Aspiration Thrombectomy ReadImageable Radioembolization Microspheres for Treatment of Unresectable Hepatocellular Carcinoma: Interim Results from a First-in-Human Trial ReadMagnetic Resonance Imaging–Guided Cryoablation of Prostate Cancer Lymph Node Metastasis ReadCorrelation of Ablation Volume with Renal Function Loss after Cryoablation in Solitary Functioning Kidneys ReadIntra-arterial Pressure-Enabled Drug Delivery Significantly Increases Penetration of Glass Microspheres in a Porcine Liver Tumor Model ReadJVIR and SIR thank all those who helped record this episode:Host:Manbir Singh Sandhu, University of California Riverside School of MedicineAudio editor:Sonya Choe, University of California Riverside School of MedicineAbstract readers:Melissa Millett, MD, Southeast HealthSonya Choe, University of California Riverside School of MedicineAlena Khalil, Nova Southeastern University Dr. Kiran Patel College of Osteopathic MedicineAndrew Brandser, Frank H. Netter MD School of MedicineMark Oliinik, Loma Linda University School of MedicineDaniel Roh, Loma Linda University School of MedicineMillennie Chen, University of California Riverside School of MedicineSupport the showSupport the show

PE's (or Pulmonary Emboli) are a key part of Emergency Care, something that many of us will consider as a differential diagnosis multiple times of a daily basis, in a similar way to acute coronary syndrome, so we need to be absolute experts on the topic! A PE normally occurs when a Deep Vein Thrombosis shoots off to the pulmonary arterial tree, occurring in 60-120 per 100,000 of the population per year The inhospital mortality is 14% and the 90 day mortality is around 20%. But this is proportional to its size, and risk stratifying PE's once we've got the diagnosis is really important. PE is a real diagnostic challenge and less than 1 in 10 who are investigated for a PE end up with the diagnosis, so knowing the risk factors, associated features and thresholds for work up are really important. There are some key concepts in risk stratification and particularly in test thresholds that we'll cover in this episode that are applicable to all of our practice…..we're excited! Getting these right helps us to avoid missing the diagnosis and equally importantly ensure we aren't ‘over testing' & ‘over diagnosing' because investigation and treatment for a PE isn't without it's own risks. In the episode we'll talk in depth about factors associated with presentation, risk factors, investigations and finally onto treatments, covering the whole spectrum from low risk PE's up to those with massive PE's and cardiac arrest. The evidence base behind the work up and treatments is truly fascinating and we hope you find this episode as eye-opening as we did to prepare for! Once again we'd love to hear any thoughts or feedback either on the website or via X @TheResusRoom! Simon, Rob & James

Beat king's sudden death scary facts about pulmonary embolism we should knowAvailable on all podcast streaming services:https://thehighestpointpodcast.buzzsprout.com/Instagram: https://www.instagram.com/thehighestpointpodcastSupport the show: https://www.cash.app/$highestpointenthttps://www.paypal.com/paypalme/highestpointpodcast#beatkingsumedh #pulmonaryembolism #thehighestpointpodcast #bloodclottingSupport the Show.

Welcome to the latest episode of Medmastery's Cardiology Digest, where In less than 15 minutes we'll get you up to date on breakthrough studies and advancements in cardiology that can impact your clinical practice! STUDY #1: Brace yourself for insights into a study that evaluated rapid uptitration of evidence-based therapies for heart failure. Join us as we dissect the feasibility, resource demands, and patient implications?  Biegus, J, Mebazaa, A, Davison, B, et al. 2024. Effects of rapid uptitration of neurohormonal blockade on effective, sustainable decongestion and outcomes in STRONG-HF. J Am Coll Cardiol. 4: 323–336.  (https://doi.org/10.1016/j.jacc.2024.04.055) STUDY #2: Next, we examine a recent paper that challenges hospital-centric treatment paradigms for acute pulmonary embolism. Discover how some low-risk patients could benefit from home treatment, and what conditions are essential to ensure their safety and effective care.  Luijten, D, Douillet, D, Luijken, K, et al. 2024. Safety of treating acute pulmonary embolism at home: An individual patient data meta-analysis. Eur Heart J. 32: 2933–2950. (https://doi.org/10.1093/eurheartj/ehae378) STUDY #3: Finally, we dive into a large cohort study looking at bariatric surgery in obese patients with obstructive sleep apnea, and see whether losing weight actually had a significant impact on cardiovascular outcomes. Aminian, A, Wang, L, Al Jabri, A, et al. 2024. Adverse cardiovascular outcomes in patients with obstructive sleep apnea and obesity: Metabolic surgery vs usual care. J Am Coll Cardiol. Published online. (https://doi.org/10.1016/j.jacc.2024.06.008) This episode promises to be packed with actionable insights on this thought-provoking cardiology research. Don't miss out—press play and enrich your practice today!  Learn more with Medmastery's courses: Chest X-ray Essentials (7 CME) Chest X-ray Essentials Workshop (1 CME) Get a Basic or Pro account, or, get a Trial account. Show notes: Visit us at  https://www.medmastery.com/podcasts/cardiology-podcast.

The crew is back together to talk about Do you know what Demure is? Family Matter Hurricane Chris is mad at 50 Cent for throwing an event & allegedly not booking any Louisiana artists Lil Durk says he doesn't gang bang and reaffirms his belief as a Muslim DEADPOOL & WOLVERINE' has become the highest grossing R-rated movie of all time, passing ‘JOKER'. The movie has made over $1B in 3 weeks. T.I. Hypes Up Young Thug Prison Release as Fulton County D.A. Race Hinges YSL RICO Case Kash Doll Shares There Was a Home Invasion at Her Atlanta House That Ended in a Shootout — Calls Out Community Leader Who Told the Local News Her Home Was A “Drug House” Complex has crowned Andre 3000, Future, T.I., Gucci Mane and Jeezy as the top five best rappers from Atlanta. The full list consisted of 50 rappers Simone Biles' Birth Mom Pleads w/ Olympic Gymnast to Forgive Her Following Decades-Long Estrangement Sexyy Red Reveals She Was Going Through Postpartum While Making Hit Song ‘Get It Sexyy' Tennis Star Naomi Osaka Speaks on How Postpartum Changes Has Affected Her on The Court: ‘I Don't Feel Like I'm In My Body' BeatKing's cause of death was revealed to be Pulmonary Embolism, a condition where arteries in the lungs become blocked by a blood clot. Sukihana says she outgrew her old self and regrets getting a machine gun tattooed on her buttocks: “I wish someone stopped me” Trick Daddy opens up about his attractiveness for GloRilla on Instagram live Michael Rubin says he hates that the black community tears down Meek Mill and claims Meek doesn't have a “gay” bone in his body ScHoolboy Q Slams Michael Rubin for Criticism on The Black Community: ‘This Sh*t Outta Control' Real beef is back, Tokyo Vanity came to the internet for a victory lap after snatching rapper Amy Luciani's chain then Amy got a hold of her dog is threatening to sell it unless her Ice is returned Stunna Girl decided to call it quits with her husband Young Rich Mula as she claims he ran when she got shot. EST Gee's artist EST Lu Mike was shot & killed last night In Louisville, Kentucky. This is weeks after his manager was killed in Kentucky Boston Richey fans are mad at blogs for posting old videos of him snitching in an interrogation room. “Y'all wait for him to get a hit song to bring it back up??” Jazmine Cheaves is facing backlash after saying she does not like when her 5-month-old baby boy yells: “I don't like when he do that screaming sh*t, he's not a girl” Latto, Sexyy Red, and Flo Milli Explain the Reason They Believe Female Rappers Are Dominating in Hip-Hop: “We the ones bringing the versatility. Courtney Kramer, who is challenging Fani Willis for the position of Fulton County DA, is looking to fully dismiss the YSL trial. She claims that, if elected, her first official action would be to have the case dropped immediately, freeing Young Thug and several others. This man may have to cancel his wedding after family & friends all declined because he was charging his guest $450 each because he he spent 200,000 on it

DISCLAMER >>>>>>    The Ditch Lab Coat podcast serves solely for general informational purposes and does not serve as a substitute for professional medical services such as medicine or nursing. It does not establish a doctor/patient relationship, and the use of information from the podcast or linked materials is at the user's own risk. The content does not aim to replace professional medical advice, diagnosis, or treatment, and users should promptly seek guidance from healthcare professionals for any medical conditions.   >>>>>> The expressed opinions belong solely to the hosts and guests, and they do not necessarily reflect the views or opinions of the Hospitals, Clinics, Universities, or any other organization associated with the host or guests.       Disclosures: Ditch The Lab Coat podcast is produced by (Podkind.co) and is independent of Dr. Bonta's teaching and research roles at McMaster University, Temerty Faculty of Medicine and Queens University. Welcome back to "Ditch the Lab Coat," the podcast where we explore the fascinating world of health and medicine with a skeptical eye. I'm Dr. Mark Bonta and In today's episode, Dr. Kaplovitch dives deep into the different types of blood clots and the importance of personalized treatment. He explains that not all blood clots are created equal - some predominantly affect the veins, while others can travel to the lungs and become life-threatening. We discuss the various risk factors that can lead to blood clot formation, from genetic conditions to long plane rides, and Dr. Kaplovitch offers practical advice on managing this complex disorder.We also touch on the fascinating history behind some blood thinning medications, like warfarin, which was originally used as rat poison! Dr. Kaplovitch clarifies the distinctions between its toxic properties and medical use. Throughout our conversation, we emphasize the importance of transparently counseling patients about the risks and benefits of different treatments. Dr. Kaplovitch highlights the abundance of research in the field of thrombosis and how it informs the personalized approach he takes with his patients.So join us as we simplify these complex medical concepts and explore the latest advancements in blood clot prevention and treatment. As always, remember that this podcast is for informational purposes only and does not substitute for professional medical advice. Let's ditch the lab coat and dive in!04:24 Experienced medical student impresses with professionalism.09:02 Blood clots can travel to lungs, fatal.12:14 Prolonged sitting at desk may increase thrombosis risk.16:01 Minority with blood clots can improve naturally.18:45 Clot busters have significant risk of bleeding.20:59 Treatment options for preventing blood clot complications.25:39 Passion for vascular medicine, citing primary literature.29:26 Newer blood thinners may have advantages.31:37 Warfarin inhibits clotting by blocking vitamin K.36:09 Balancing blood thinness for health benefits is crucial.37:22 Maintain optimal blood thinness to prevent risks.42:22 Minor bleeding from gut might not require action.46:27 Consistent blood thinner use is crucial.50:05 Discussing evolving thrombosis practices, specifically genetic testing controversies.51:24 Testing for clotting disorders requires informed discussion.57:02 Advancements in personalized medicine revolutionize treatment.58:45 Hip hop slang reference and deep thrombosis.

This recording features audio versions of August 2024 Journal of Vascular and Interventional Radiology (JVIR) abstracts:Safety and Effectiveness of Endovascular Treatment of Complications Associated with Persistent Sciatic Artery: A Qualitative Systematic Review ReadA Qualitative Systematic Review of Endovascular Management of Renal Artery Aneurysms ReadHemorrhagic Adverse Events of Transthoracic Needle Biopsy of the Lung in Patients with Pulmonary Hypertension: A Systematic Review and Meta-Analysis ReadRecurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension ReadClinical, Functional, and Quality-of-Life Outcomes after Computer Assisted Vacuum Thrombectomy for Pulmonary Embolism: Interim Analysis of the STRIKE-PE Study ReadSafety and Effectiveness of Track Cauterization for Lung Cryoablation ReadComparison of Outcomes of Drug-Coated Balloons versus Plain Balloons in Secondary Interventions on Percutaneous Arteriovenous Fistulae ReadTransperineal Laser Ablation of the Prostate for Symptomatic Benign Prostatic Hyperplasia: Long-Term Follow-Up in 40 Patients ReadJVIR and SIR thank all those who helped record this episode:Host:Manbir Singh Sandhu, University of California Riverside School of MedicineAudio editor:Hannah Curtis, Loma Linda University School of MedicineAbstract readers:Vasan Jagadeesh, University of California San Diego School of MedicineDhanush Reddy, MBBS, Massachusetts General HospitalAshwin Mahendra, Florida Atlantic University Charles E. Schmidt College of MedicineTaji Kommineni, MD, JD, LLM, Emory UniversityAnna Hu, George Washington University School of Medicine and Health SciencesBrian Ng, MD, University of California Los AngelesJack Ficke, Frank H. Netter School of MedicineMark Oliinik,  Loma Linda University School of Medicine©  Society of Interventional RadiologySupport the Show.

In this episode, we review the high-yield topic of ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Pulmonary Embolism ⁠⁠⁠⁠⁠⁠⁠⁠from the Pulmonary section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets

Podcast summary of articles from the April 2024 edition of the Journal of Emergency Medicine from the American Academy of Emergency Medicine.  Topics include co-ventliation, handheld ultrasound for POCUS, naloxone, hyperkalemia, pulmonary embolisms, and multiple sclerosis.  Guest speaker is Dr. Daniel Boyes.

Emily Goldberg, known for her relationship with the late EDM DJ Avicii, has died at the young age of 34 from a pulmonary embolism after bravely battling cancer, RadarOnline.com has learned.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Pulmonary Embolism EKG by Albuquerque Fire Rescue

If you're learning about advanced Med Surg concepts or even working in the clinical setting, you've no doubt heard of pulmonary embolism. But did you know it goes beyond impaired gas exchange? Hit play on this episode to learn how a pulmonary embolism can impair cardiac function, potentially leading to devastating consequences. In this episode, you'll review foundation concepts to help you understand this connection: Cardiopulmonary circulation Pulmonary embolism pathophysiology The factors that contribute to blood pressure ___________________ Full Transcript - Read the article and view references (put the link where it says FULL TRANSCRIPT) FREE CLASS - If all you've heard are nursing school horror stories, then you need this class! Join me in this on-demand session where I dispel all those nursing school myths and show you that YES...you can thrive in nursing school without it taking over your life! Med Surg Solution - Are you looking for a more effective way to learn Med Surg? Enroll in Med Surg Solution and get lessons on 57 key topics and out-of-this-world study guides. Include if we're talking about MSS

Although we look very different from many of the other creatures on this planet, we're more connected than you might think. Our evolutionary history means we share many of the same genes and physiology, and that's not just cool to think about — it's useful. Because it means that, to learn about the things we lack or wish we could do better, we can study the exceptional abilities of other animals.In today's episode, Sam and Deboki cover two species with extreme lifestyles— brown bears and Mexican cave fish — and what they are teaching us about avoiding blood clots and fatty liver disease, and how that could unlock the potential for new treatments. In this week's Tiny Show and Tell, Sam asks "What is a species?" and Deboki ponders how a mushroom could grow out of a living frog.Links to the Tiny Show & Tell stories are here and here. Support the show by picking up a Tiny Matters mug here! All Tiny Matters transcripts are available here.

In this episode, Daniel Belkin and Mitch Belkin interview Marc Gosselin, MD about his journey to radiology, being a radiology program director, dealing with burnout, transitioning from academics to private practice, and overdiagnosis in radiology. They discuss in situ thrombosis versus pulmonary emboli, whether medical evidence should have an expiration date, and why physicians should admit fault when they are wrong.Who is Marc Gosselin?Dr. Marc Gosselin is the head of cardiopulmonary imaging at Vision radiology, a retired full professor at Oregon Health and Science University. Previously, Dr. Gosselin was a program director of the University of Utah's radiology program.References:Clinical Features of Pulmonary Embolism (1961)Sensible Medicine: Why statins do not cause diabetesSupport the showFollow us at @ExMedPod Subscribe to our Youtube channelConsider supporting us on Patreon

In this episode of the BackTable Podcast, host Dr. Aaron Fritts interviews guest Dr. Ilan Rzadkowolsky-Raoli about his experience of being diagnosed with a large saddle embolus and subsequently being treated by his best friend, Dr. Ripal Gandhi. Dr. Rzadkowolsky-Raoli is an interventional radiologist at Palmetto General Hospital in Miami, Florida. Dr. Rzadkowolsky-Raoli discusses the impact of his diagnosis on his practice, how it has changed the way he approaches and speaks to his patients, and his advice for clinicians. --- CHECK OUT OUR SPONSORS Varian, a Siemens Healthineers company https://www.varian.com/products/interventional-solutions/embolization-solutions Medtronic ClosureFast https://www.medtronic.com/closurefast6f --- SHOW NOTES 00:00 - Introduction 06:18 - Dr. Rzadkowolsky-Raoli's Personal Journey 09:41 - Diagnosis and Treatment Process 12:18 - Post-Treatment Recovery and Reflections 24:18 - Impact on Practice and Patient Care 31:45 - Final Thoughts and Appreciation --- RESOURCES Pulmonary Embolism Response Team (PERT) Consortium: https://pertconsortium.org/ Inari FlowTriever: https://www.inarimedical.com/flowtriever/

In this conversation, Danielle Jensen shares her journey of battling ovarian cancer and dealing with other health challenges. She worked for Sam and discusses her experiences during her time with him.  Danielle talks about her diagnosis, the side effects of chemotherapy, and the emotional impact of losing her hair.  She also shares her experiences with pulmonary embolism, pulmonary hypertension, and the surgery she underwent to treat her condition.  Danielle opens up about questioning her faith and the importance of having a patient advocate when dealing with medical professionals.  The conversation explores themes of trust, fear, reflection, faith, and political beliefs. It delves into the contrast between trusting Google and believing in the Bible, the fear of death and the afterlife, reflecting on life's chances, sharing personal beliefs and faith, the emasculation of men, and the importance of not looking for a political savior.TakeawaysHaving a patient advocate can be crucial when dealing with complex medical conditions.Side effects of chemotherapy can include joint pain, nausea, and hair loss.Questioning one's faith during challenging times is a natural part of the journey.Open and honest communication with medical professionals is important for understanding and managing one's condition.Googling medical conditions can provide information, but it's important to rely on reputable sources and consult with healthcare professionals. Trust in something greater than technology and popular opinion.Confront and understand the fear of death and the afterlife.Reflect on how you are using your chances and heartbeats in life.Share your beliefs and faith with others, especially during challenging times.Explore the impact of societal expectations on masculinity.Shift focus from seeking a political savior to finding solace in Jesus.Chapters00:00 Introduction03:00 Working for Sam Fischer06:00 Challenges and Diagnosis09:00 Ovarian Cancer and Treatment13:00 Side Effects of Chemotherapy16:00 Hair Loss and Coping19:00 Pulmonary Embolism and Pulmonary Hypertension22:00 CTEP and Surgery27:00 Seizure and Recovery37:00 Questioning Faith42:00 Communication with Medical Professionals45:00 Googling Medical Conditions45:47 Trust in Google vs. Belief in the Bible46:46 Fear of Death and the Afterlife48:10 Reflecting on Life's Chances49:05 Sharing Beliefs and Faith50:02 The Emasculation of Men50:55 Stop Looking for a Political SaviorSupport the showThanks for listening! SUBSCRIBE, Review, Rate, and Share. Contact us: cowboysnoteggheads@gmail.com Let us know if you want a hat ($20), tee shirt ($30), coffee cup ($25), or window decal for your truck. ($30)

Tune in for a multi-disciplinary panel discussion on the latest real-world data and advanced endovascular strategies for PE management  

In Part II of our discussion of PE, Nick & Cyrus discuss the Pillars of PE Management! We review the literature behind lytics in non-massive PEs, talk about airway management, hemodynamics and more! Make sure you listen to Part I if you missed it as it sets the stage for this fantastic, treatment focused discussion. Hosted on Acast. See acast.com/privacy for more information.

  “So much of this is just knowing what is their diagnosis, what medications are they on, what could be the root cause of this—where is their disease to begin with? There's really a lot of differential diagnosis and workup that has to be thought about, you know, when you're dealing with shortness of breath and pulmonary toxicities,” Beth Sandy, MSN, CRNP, OCN®, thoracic medical oncology nurse practitioner at the Abramson Cancer Center at the University of Pennsylvania in Philadelphia, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a discussion about just a few of the pulmonary toxicities oncology nurses may encounter in patients receiving pharmaceutical cancer treatments. This episode is part of a series on cancer symptom management basics; the rest are linked below.  You can earn free NCPD contact hours after listening to this episode and completing the evaluation linked below.   Music Credit: “Fireflies and Stardust” by Kevin MacLeod  Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD), which may be applied to the nursing practice, oncology nursing practice, symptom management, palliative care, supportive care, or treatment.ILNA categories, by listening to the full recording and completing an evaluation at myoutcomes.ons.org by January 19, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of NCPD by the American Nurses Credentialing Center's Commission on Accreditation.  Learning outcome: The learner will report an increase in knowledge of pulmonary complications from cancer treatment.   Episode Notes  Complete this evaluation for free NCPD.   Oncology Nursing Podcast Cancer Symptom Management Basics series  ONS Voice articles: Pneumonitis With Immunotherapy Treatment Hematologic Cancers Have Higher Long-Term Risk of Clots and Bleeding  Clinical Journal of Oncology Nursing articles: Durvalumab Immunotherapy: Nursing Management of Immune-Related Adverse Events During the Journey of Patients With Stage III Non-Small Cell Lung Cancer Heart and Lung Complications: Assessment and Prevention of Venous Thromboembolism and Cardiovascular Disease in Patients With Multiple Myeloma Chronic Obstructive Pulmonary Disease: Clinical Implications for Patients With Lung Cancer  Oncology Nursing Forum article: Multifactorial Model of Dyspnea in Patients With Cancer  ONS book: Understanding and Managing Oncologic Emergencies: A Resource for Nurses (third edition)  ONS Symptom Interventions and Guidelines™: Dyspnea  To discuss the information in this episode with other oncology nurses, visit the ONS Communities.    To find resources for creating an ONS Podcast Club in your chapter or nursing community, visit the ONS Podcast Library.  To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org.  Highlights From Today's Episode  “Your lungs are what is needed to have the gas exchange within your bloodstream. So, when we inhale, we're inhaling oxygen, and we need that gas exchange to occur in the alveoli, which are the tiny, little bubble-like structures within the periphery of the lungs. And they're communicating with tiny, itty-bitty little blood vessels. And that's where the gas exchange occurs, where you get rid of the carbon dioxide from the blood and you get oxygen to the blood. And what ends up happening is there is, for whatever reason it may be, that gas exchange can't occur, and that can result in so many different forms from different toxicities, whether there's an inflammation causing the alveoli not to work correctly, whether there's an obstruction where there's literally something obstructing the air getting into the lungs, or whether there's compression from an external source like a fusion or something like that that is pressing against the lungs where that gas exchange cannot occur.” TS 2:36  “Pulmonary embolism, I'll tell you, is one of the most common things that we see in cancer. As a matter of fact, often patients are diagnosed with cancer because they present with a pulmonary embolism into the E.R. (emergency room) and there's really not a lot of reasons why healthy-otherwise patients develop a PE [pulmonary embolism]. So, we start looking for cancer. So, just having cancer in general puts you in that hypercoagulable state. . . . And then, being on chemotherapy increases that risk.” TS 6:38  “I think we need to really make sure that they're compliant. We need to make sure they're not having bleeding. Are you having significant bruising anywhere? Are you having unprovoked nosebleeds? And by that, I mean, I always tell people, ‘Were you just sitting watching TV and it started dripping?' versus, ‘Oh, I blew my nose and some blood came out.' Okay, well, that is probably pretty common side effect of this and should stop quickly.” TS 12:06  “The problem is the majority of these patients have metastatic disease or an incurable cancer. So, we prefer not to stop it [PE medication] in those patients because if you think about it, their risk comes from the cancer. And we're not getting rid of that if they have metastatic disease. I think for those patients with metastatic disease, as long as they're tolerating it, they're not having bleeding events, we will typically tend to just keep them on it.” TS 13:09  “The main difference with the targeted therapies is it tends to be worse, and it's not something that you can rechallenge. And I think that's kind of one of the most important things to think about here. In immunotherapy, it's like, okay, it's T-cell mediated; we gave you corticosteroids; it calmed itself down. And a lot of times we can rechallenge, and we don't necessarily see it again. Whereas with targeted therapies, you have to be much more cautious. If you look at the package inserts for the EGFR and ALK inhibitors, most of them are going to tell you this is not something you ever rechallenge. Any kind of symptomatic pneumonitis, you're going to permanently discontinue the drug. Because if you give it again, it's going to recur in a pretty bad way, where corticosteroids may not even be helpful again even if you rechallenge them.” TS 17:52  “What can happen in cancer, typically, thoracic cancers—so lung cancer, mesothelioma for sure, thymic cancers like thymomas and thymic carcinomas—often will have pleural effusion or pleural disease as well. But when cancer cells get into that fluid, there's irritation which causes an increase in the amount of fluid there. And then what happens is when that space, that pleural space, is now enlarged with fluid or engorged with fluid, a few things occur here. Patients are short of breath because it's a pressure gradient there. So, you're trying to inhale against this fluid-filled cavity that's making it hard. So, often patients will describe it as it feels like someone's giving you a really tight hug and they won't stop.” TS 21:59  “There is another procedure called a talc pleurodesis, where you can have a procedure where you inject some powder in there that will kind of dry it up. The downside of that is that it kind of fuses the pleura to the lung, so there can be some complications there, some pain, and decreased lung function just from doing that, but it can be an easy fix that you certainly don't want to have an indwelling catheter there.” TS 25:11  “So, patients need to know, if they are short of breath at all, call us; let us know. The other thing that's important is know with their baseline vital signs are, especially their pulse ox. You know, some people, their pulse oximetry may be in the low 90s or upper 80s at baseline. We need to know that because there's a big difference if a patient has, you know, they're living at 99% versus 91% normally. Because if they come in and they live at 99 and they're 91, that's a huge drop. But if they come in and they were 91 to begin with and they're 90, that's not a big difference. So, we really do need to make sure we know what their baseline is before they're starting any treatments.” TS 29:18  “This is not something that you want to downplay. You can't sit there and say, you know, ‘Oh, they smoke a lot, so it's probably that.' Or, ‘They have this type of cancer, so it's probably that.' I think this is something that you have to take shortness of breath seriously, and you have to work up and understand and know your patient. But for the most part, this is not something you're going to just triage to the next day or to a few days later. You're going to need some kind of urgent intervention or workup to be done pretty quickly.” TS 32:54  “I think the biggest misconception is that they can't be treated even if they're severe. Most of these things can be reversed. Part of it is just diagnosing it at first and then going from there and starting the appropriate treatment strategy.” TS 33:29 

Diagnosing PE: Step 1: Consciously consider the diagnosis Step 2: Risk Stratify into low, intermediate, and high risk Step 3: Choose appropriate testing based on pre-test probability Classification of PE Treatment of PE

There are few things in medicine Nick & Cyrus enjoy talking about more than PE! Join the guys from Critical Care Time as they tackle this massive topic via a two part epic that'll prove to be the best saga since The Lord of The Rings! In part one they talk about diagnosis, clinical decision support tools and demystify the pathophysiology behind pulmonary emboli. Check it out, and be sure to catch the second half in two weeks! We promise you'll get your money's worth! Hosted on Acast. See acast.com/privacy for more information.

Welcome to our first guest episode of 2024! Season 4 is upon us and we are thrilled to have Michelle Glogovac on the show to kick us off! Michelle lost her father at 7 years old, and soon after had to deal with an absent mother for reasons she will explain! Michelle realized she had to fend for herself and worked hard through school and secured a corporate job that she continued for nearly two decades! When she was let go, now a mother of two kids (born one year apart!!), Michelle decided it was time for a pivot in her career. It was at about this time when Michelle had a pain in her back, but something was not quite right, it felt different.  Michelle explains how she fought to get seen by a doctor (they told her it wasn't and emergency and to come in 'later in the week',  so she went to the ER, where they would eventually discover blood clots on her lungs, and require immediate life saving treatment! The doctor said she would be dead of she had waited for the appointment 'later in the week'.Links for Michelle:Podcast: https://podcasts.apple.com/us/podcast/my-simplified-life/id1479782634Agency: https://themlgcollective.com/IG: https://www.instagram.com/michelleglogovac/FB: https://www.facebook.com/TheMLGCollective/Support the show