Podcasts about TRIC

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  • 778EPISODES
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  • May 15, 2025LATEST

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Best podcasts about TRIC

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Latest podcast episodes about TRIC

TheValveCast
Click Valvar Academy #632 - Regurgitação Tricúspide na presença de uma ICFEp

TheValveCast

Play Episode Listen Later May 15, 2025 4:07


No Click Valvar Academy de hoje temos grandes insights sobre Regurgitação Tricúspide na presença de uma ICFEp. Ficou demais!

Dicey Stories
DS384 | Wesnoth | Echoes of Invasion: Saurian Standoff | Part 3 of 3

Dicey Stories

Play Episode Listen Later May 14, 2025 47:09


Elves, humans, and saurians recover from the assault. Scene 8 Scene 9 Scene 10 GM Notes I originally thought the campaign was going to end with a trek across the Bitter Swamp to Mal-Ravanal's fortress for a final showdown there. I was going to ambush the players with drakes along the route. However, as events in our story developed organically, that ending grew less and less likely. I still wanted to bring in drakes, though, and having them attack the saurian allies was the perfect opportunity. I don't feel like I managed to make my drakes quite as intimidating as the ones in the Battle for Wesnoth video game, but I was still glad to give Drake Gliders and Clashers some air time. You also got to hear Tric spout lore about Flamehearts. As for other units from the video game, this combat let us see the pinnacle of saurian fighting prowess, the Flanker, as well as a return of our old friend, the Mudcrawler. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS380 | Wesnoth | Echoes of Invasion: Saurian Standoff | Part 1 of 3

Dicey Stories

Play Episode Listen Later Apr 30, 2025 52:42


Tric and Heppa experience daily saurian life up close and learn more about the society. Scene 1 Scene 2 Scene 3 Scene 4 GM Notes Of all the peoples that Tric and Heppa interacted with during this campaign, the saurians have always felt to me like the most foreign. They have very short lives, they have a very rigid gender divide in their societal roles, and they are not mammalian. Those are all details drawn from their entry in the Battle for Wesnoth wiki. I decided to lean further into all that in this arc, inspired by the various fish, reptiles, and amphibians that can change sex (ref: https://www.treehugger.com/animals-can-change-their-sex-4869361). Although Salras is not transgender in the same sense as a human in the real world might be, I did talk with the transgender player in our group prior to introducing this topic, just to make sure I handled it in a way we would all be comfortable with. This arc contains spoilers for the Battle for Wesnoth campaigns Eastern Invasion and the Legend of Wesmere, as well as references to Ashen Hearts, a User-Made Content campaign. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS376 | Wesnoth | Echoes of Invasion: The Heist | Part 4 of 5

Dicey Stories

Play Episode Listen Later Apr 16, 2025 65:35


Wolf-mounted goblins pursue Tric, Heppa, and their loaded cart of recovered people and items. Scene 11 Scene 12 Note: This episode uses our Chase rules. Find them here. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

[Video] SuperToast
⚡️ Basecamp 20Xe: uma roulote de campismo totalmente elétric

[Video] SuperToast

Play Episode Listen Later Apr 8, 2025 1:32


A Basecamp 20Xe é uma roulote totalmente elétrica da Airstream, concebida para oferecer uma maior "independência energética" aos campistas e possibilitar aventuras em locais remotos sem depender de infraestruturas convencionais. Esta roulote oferece uma autonomia significativamente maior relativamente aos modelos anteriores, permitindo estadias prolongadas em locais isolados.

SuperToast by FABERNOVEL
⚡️ Basecamp 20Xe: uma roulote de campismo totalmente elétric

SuperToast by FABERNOVEL

Play Episode Listen Later Apr 8, 2025 1:32


A Basecamp 20Xe é uma roulote totalmente elétrica da Airstream, concebida para oferecer uma maior "independência energética" aos campistas e possibilitar aventuras em locais remotos sem depender de infraestruturas convencionais. Esta roulote oferece uma autonomia significativamente maior relativamente aos modelos anteriores, permitindo estadias prolongadas em locais isolados.

Hora 14 Catalunya
Vall d'Hebron fa el primer trasplantament simultani pediàtric de cor i fetge de l'estat

Hora 14 Catalunya

Play Episode Listen Later Mar 21, 2025 1:19


La intervenció, que es va fer a finals de 2024 ha permès  que el pacient, un noi de 16 anys que va néixer amb un sol ventricle, pugui tornar a fer vida normal

Dicey Stories
DS368 | Wesnoth | Echoes of Invasion: The Battlefield | Part 7 of 7

Dicey Stories

Play Episode Listen Later Mar 19, 2025 45:26


Each in their own way, Tric and Heppa seek to improve Kachen's situation. Scene 16 Scene 17 Scene 18 Scene 19 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS366 | Wesnoth | Echoes of Invasion: The Battlefield | Part 6 of 7

Dicey Stories

Play Episode Listen Later Mar 12, 2025 54:36


Heppa and Tric enjoy a discussion of magic theory with Cwuml, a silver mage. Scene 13 Scene 14 Scene 15 GM Notes Tric's story about using symbols to teleport between established locations was inspired by the teleportation system in the video game, Betrayal at Krondor. I've never played it myself, but Tric's player did when she was younger. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS364 | Wesnoth | Echoes of Invasion: The Battlefield | Part 5 of 7

Dicey Stories

Play Episode Listen Later Mar 5, 2025 33:46


While Heppa sees to one more patient, Tric gains one more quest. Scene 11 Scene 12 GM Notes Lots of units from the Battle for Wesnoth video game are going to come out in this epic battle, as I'm sure you can imagine. We had a Goblin Pillager and an Orcish Crossbowman menacing Heledd in her Rhaessa disguise, and we referred to Tric not being Dunefolk enough to be a Horse Archer. Endathalas was chewed on by a Ghast, and Tric encouraged him to be an Elvish Rider, which is the upgrade of the Elvish Scout. And of course, there are the Chocobones, which I always find a real challenge in the video game, as well as Terwaen's promotion from Knight to Paladin. We also finally get our first Silver Mage! Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS362 | Wesnoth | Echoes of Invasion: The Battlefield | Part 4 of 7

Dicey Stories

Play Episode Listen Later Feb 26, 2025 43:55


Terwaen secures medical treatment for Tric and Heppa, who in turn secure her a promotion. Scene 9 Scene 10 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS360 | Wesnoth | Echoes of Invasion: The Battlefield | Part 3 of 7

Dicey Stories

Play Episode Listen Later Feb 19, 2025 56:19


Vicious skeletal cavalry threaten Tric's carefully selected team. Scene 7 Scene 8 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS358 | Wesnoth | Echoes of Invasion: The Battlefield | Part 2 of 7

Dicey Stories

Play Episode Listen Later Feb 12, 2025 45:13


Tric's crack team braves the dangers of the swamps. Scene 4 Scene 5 Scene 6 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS356 | Wesnoth | Echoes of Invasion: The Battlefield | Part 1 of 7

Dicey Stories

Play Episode Listen Later Feb 5, 2025 43:59


Tric leads his special scouting task force around the edge of the battlefield. Scene 1 Scene 2 Scene 3 GM Notes This episode makes reference to birds that carry and drop burning sticks. This isn't something I made up. If you're interested in learning more about this tool usage by some Australian birds, I've linked an article here: https://altoona.psu.edu/feature/researching-firehawks. This arc contains spoilers for the Battle for Wesnoth campaign Eastern Invasion, Delfador's Memoirs, and The South Guard. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

TheValveCast
Click Valvar #600 - Dispositivos para valva tricúspide e a curva de sobrevida

TheValveCast

Play Episode Listen Later Jan 23, 2025 5:13


No Click Valvar de hoje temos grandes insights sobre dispositivos para valva tricúspide e a curva de sobrevida.

SBS Vietnamese - SBS Việt ngữ
Quyết định ngừng kiểm tra thông tin trên mạng xã hội của Meta có ảnh hưởng đến cử tri Úc không?

SBS Vietnamese - SBS Việt ngữ

Play Episode Listen Later Jan 9, 2025 10:56


Công ty truyền thông xã hội khổng lồ Meta đã quyết định, ngừng sử dụng các công cụ kiểm tra thực tế của bên thứ ba trên các nền tảng của họ tại Hoa Kỳ, trong số một loạt các biện pháp mà họ cho biết, là nhằm thúc đẩy nội dung chính trị và quyền tự do ngôn luận. Thế nhưng có những lo ngại về ý nghĩa của sự thay đổi này đối với người sử dụng Úc, đặc biệt là trước cuộc bầu cử liên bang năm nay.

Dicey Stories
DS354 | Wesnoth | Echoes of Invasion: Family Matters | Part 3 of 3

Dicey Stories

Play Episode Listen Later Jan 8, 2025 39:40


Tric's contingency plans regarding Thrandolil do not go over well with Heppa. Scene 9 Scene 10 Scene 11 Scene 12 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

TheValveCast
Click Valvar #593 - Fibrilação atrial é um fator negativo para regurgitação tricúspide funcional

TheValveCast

Play Episode Listen Later Dec 30, 2024 3:40


No Click Valvar de hoje temos grandes insights sobre a fibrilação atrial e a regurgitação tricúspide funcional.

Dicey Stories
DS350 | Wesnoth | Echoes of Invasion: Family Matters | Part 1 of 3

Dicey Stories

Play Episode Listen Later Dec 25, 2024 48:49


Tric welcomes his sister Terwaen to Estbryn Forest while Heppa brings Alric in for his first visit. Scene 1 Scene 2 Scene 3 Scene 4 Scene 5 GM Notes I got the new alcoholic drink in this episode, Joli Rouge, from a song of that name by the Dreadnoughts. It's got a really fun video that think you should check out: https://www.youtube.com/watch?v=Yeh1S_kl8YI. This arc contains spoilers for the Battle for Wesnoth campaigns Eastern Invasion and South Guard. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS348 | Wesnoth | Echoes of Invasion: Overwintering | Part 6 of 6

Dicey Stories

Play Episode Listen Later Dec 18, 2024 61:38


Tric and Heppa pay the dwarves of Untdunben another visit. Scene 13 Scene 14 Scene 15 Scene 16 GM Notes There are no trains in the Battle for Wesnoth video game, at least not any of the campaigns I've played. So why do these dwarves have a train? Well, while contemplating this rematch with the dwarves of Untdunben, I rolled on the Mythic GM Emulator's event meaning tables for inspiration and got Develop and Vehicle. Mining tracks are well-established in the video game, so I decided they weren't all for carts—some were for trains. Oh, and if you're interested in the songs that you heard snippets of from Tric's player, one was On the Railroad by The Longest Johns (https://www.youtube.com/watch?v=udICE0keewk), and the other was an American folk song called Red Iron Ore. We like the version performed by Bob Gibson (https://www.youtube.com/watch?v=Sbt6_gmAfqE). Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

SBS Vietnamese - SBS Việt ngữ
Tân nữ Chủ Tịch đầu tiên của Cộng Đồng Người Việt Tự Do Úc Châu tiểu bang Nam Úc

SBS Vietnamese - SBS Việt ngữ

Play Episode Listen Later Dec 12, 2024 17:02


Cộng đồng Người Việt Tự do Úc Châu tiểu bang Nam Úc đã có Ban Chấp Hành mới mà tên chính thức gọi là Hội Đồng Quản Trị Cộng Đồng, được người Việt Nam Úc bầu lên với số phiếu kỷ lục. Nữ Chủ tịch đầu tiên của Nam Úc là bà Trần Thị Kim Khuyên cho biết, khái quát về bản thân và sinh hoạt Tết sắp tới của Cộng đồng.

Dicey Stories
DS346 | Wesnoth | Echoes of Invasion: Overwintering | Part 5 of 6

Dicey Stories

Play Episode Listen Later Dec 11, 2024 47:07


Tric and Heppa negotiate with saurians. Scene 10 Scene 11 Scene 12 GM Notes This arc, we used a number of video game units to help flesh out our story. Tric imagined Breda as an Elvish Captain. Quemilya's magic theory discussion was influenced by the Sorceress write-up, as Tric's training is by the one for the Elvish Lord. And some of the rapid-seeming changes in the society of our short-lived saurian allies came from the descriptions and artwork of such units as Skirmisher, Ambusher, and Soothsayer. Some cultural details are pulled from the general overview of saurians on the Wesnoth wiki, but I put my own spin on them. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS344 | Wesnoth | Echoes of Invasion: Overwintering | Part 4 of 6

Dicey Stories

Play Episode Listen Later Dec 4, 2024 48:16


Tric and Heppa return to the Foul Fen. Scene 8 Scene 9 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

VOV - Chương trình thời sự
THỜI SỰ 12H TRƯA 03/12/2024: Tổng Bí thư Tô Lâm tiếp xúc cử tri các quận Ba Đình, Hai Bà Trưng và Đống Đa, thành phố Hà Nội

VOV - Chương trình thời sự

Play Episode Listen Later Dec 3, 2024 56:36


- Tổng Bí thư Tô Lâm tiếp xúc cử tri các quận Ba Đình, Hai Bà Trưng và Đống Đa, thành phố Hà Nội- Chủ tịch nước Lương Cường, Trưởng Ban Chỉ đạo Cải cách tư pháp Trung ương làm việc với Viện kiểm sát nhân dân tối cao- Kiểm tra tiến độ xây dựng sân bay Long Thành và hệ thống tuyến đường kết nối sân bay với giao thông khu vực, Thủ tướng Phạm Minh Chính chỉ đạo phát động cuộc thi đua cao điểm 450 ngày đêm trên công trường, đưa dự án về đích vào ngày 31/12/2025- Chủ tịch Quốc hội Trần Thanh Mẫn hội kiến Tổng thống Singapore và tiếp lãnh đạo các tập đoàn, doanh nghiệp lớn của Singapore đang đầu tư tại Việt Nam- Tập đoàn nghiên cứu thị trường (IMARC) đánh giá, Việt Nam có tiềm năng trở thành một cường quốc thương mại điện tử ở khu vực Đông Nam Á- Hội đồng Bảo an Liên Hợp Quốc họp khẩn về tình hình Syria-Cộng hòa Czech chấm dứt sự phụ thuộc vào dầu mỏ của Nga từ ngày 5/12 này --- Support this podcast: https://podcasters.spotify.com/pod/show/vov1thoisu0/support

Dicey Stories
DS342 | Wesnoth | Echoes of Invasion: Overwintering | Part 3 of 6

Dicey Stories

Play Episode Listen Later Nov 27, 2024 44:21


Tric begins training in preparation for his future as an elvish lord. Scene 6 Scene 7 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS338 | Wesnoth | Echoes of Invasion: Overwintering | Part 1 of 6

Dicey Stories

Play Episode Listen Later Nov 13, 2024 48:14


Tric and Heppa return home with presents and news of the wider world. Scene 1 Scene 2 Scene 3 This arc contains spoilers for the Battle for Wesnoth campaigns Eastern Invasion and South Guard. There are also references to A War of Life and Death, a User-Made Content campaign. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS336 | Wesnoth | Echoes of Invasion: After Party | Part 6 of 6

Dicey Stories

Play Episode Listen Later Nov 6, 2024 44:30


Tric continues to clash with his mother but grows closer to Kachen. Scene 16 Scene 17 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Oncotarget
Behind the Study: Molecular Chaperones & Tumor Suppressor Stability

Oncotarget

Play Episode Listen Later Oct 24, 2024 6:15


Drs. Mehdi Mollapour, Jennifer Heritz, and Sarah Backe from SUNY Upstate Medical University (Syracuse, NY) discuss a review they co-authored that was published by Oncotarget in Volume 15, entitled, “Molecular chaperones: Guardians of tumor suppressor stability and function.” DOI - https://doi.org/10.18632/oncotarget.28653 Correspondence to - Mehdi Mollapour - mollapom@upstate.edu Video interview - https://www.youtube.com/watch?v=vEHmyemWgNo Video transcript - https://www.oncotarget.net/2024/10/24/behind-the-study-molecular-chaperones-tumor-suppressor-stability/ Abstract The term ‘tumor suppressor' describes a widely diverse set of genes that are generally involved in the suppression of metastasis, but lead to tumorigenesis upon loss-of-function mutations. Despite the protein products of tumor suppressors exhibiting drastically different structures and functions, many share a common regulatory mechanism—they are molecular chaperone ‘clients'. Clients of molecular chaperones depend on an intracellular network of chaperones and co-chaperones to maintain stability. Mutations of tumor suppressors that disrupt proper chaperoning prevent the cell from maintaining sufficient protein levels for physiological function. This review discusses the role of the molecular chaperones Hsp70 and Hsp90 in maintaining the stability and functional integrity of tumor suppressors. The contribution of cochaperones prefoldin, HOP, Aha1, p23, FNIP1/2 and Tsc1 as well as the chaperonin TRiC to tumor suppressor stability is also discussed. Genes implicated in renal cell carcinoma development—VHL, TSC1/2, and FLCN—will be used as examples to explore this concept, as well as how pathogenic mutations of tumor suppressors cause disease by disrupting protein chaperoning, maturation, and function. Sign up for free Altmetric alerts about this article: https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28653 Subscribe for free publication alerts from Oncotarget: https://www.oncotarget.com/subscribe/ Keywords - cancer, molecular chaperone, tumor suppressor, renal cell carcinoma, Birt-Hogg-Dubé (BHD) syndrome, TSC syndrome About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Dicey Stories
DS332 | Wesnoth | Echoes of Invasion: After Party | Part 4 of 6

Dicey Stories

Play Episode Listen Later Oct 23, 2024 48:11


Tric and Heppa clash with the Rats again. Scene 12 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Oncotarget
Molecular Chaperones: Guardians of Tumor Suppressor Stability

Oncotarget

Play Episode Listen Later Oct 16, 2024 3:01


BUFFALO, NY- October 16, 2024 – A new #review was #published in Oncotarget's Volume 15 on October 1, 2024, entitled, “Molecular chaperones: Guardians of tumor suppressor stability and function.” As highlighted in the abstract of this paper, "tumor suppressor" describes a diverse set of genes typically involved in suppressing metastasis, but which can lead to tumorigenesis when loss-of-function mutations occur. Despite the varied structures and functions of tumor suppressor proteins, many share a common regulatory mechanism—they are "clients" of molecular chaperones, and they rely on an intracellular network of chaperones and co-chaperones to maintain their stability. Mutations in tumor suppressors that disrupt proper chaperoning prevent cells from maintaining sufficient protein levels for normal physiological function. In their review, researchers Jennifer A. Heritz, Sarah J. Backe, and Mehdi Mollapour from SUNY Upstate Medical University and New York VA Health Care in Syracuse, New York, discuss the role of molecular chaperones Hsp70 and Hsp90 in maintaining the stability and functional integrity of tumor suppressors. They also detail the contributions of co-chaperones prefoldin, HOP, Aha1, p23, FNIP1/2, and Tsc1, as well as the chaperonin TRiC, to tumor suppressor stability. “Overall, it is clear that oncogenesis can result from the dysregulation of tumor suppressor stabilization by chaperones.” DOI - https://doi.org/10.18632/oncotarget.28653 Correspondence to - Mehdi Mollapour - mollapom@upstate.edu Video short - https://www.youtube.com/watch?v=V5OFjeqaH3A Sign up for free Altmetric alerts about this article: https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28653 Subscribe for free publication alerts from Oncotarget: https://www.oncotarget.com/subscribe/ Keywords - cancer, molecular chaperone, tumor suppressor, renal cell carcinoma, Birt-Hogg-Dubé (BHD) syndrome, TSC syndrome About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Dicey Stories
DS328 | Wesnoth | Echoes of Invasion: After Party | Part 2 of 6

Dicey Stories

Play Episode Listen Later Oct 9, 2024 65:39


Tric and Heppa learn more about Kachen's recent activities and his past with Rhaessa. Scene 6 Scene 7 Scene 8 Scene 9 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS326 | Wesnoth | Echoes of Invasion: After Party | Part 1 of 6

Dicey Stories

Play Episode Listen Later Oct 2, 2024 63:30


Alric, Heppa, Tric, and Glammur entertain themselves at South Tower's After Harvest Festival. Scene 1 Scene 2 Scene 3 Scene 4 Scene 5 GM Notes The players really enjoyed the Full Bloom festival early in our campaign, so I decided to give them a chance to experience another. Inspiration came from a lot of places. For one, there are the youtube videos by Pupsi where he carves vegetables into ocarinas and then plays pop music. Check out his performance of Africa by Toto. Another inspiration was a renaissance faire, where Danielle and I saw a melon catapult years ago. The shoveling part of the pitchfork competition was inspired by a sand shoveling competition we saw at another fair. The throwing part was because in the Battle for Wesnoth video game the Peasant unit has a ranged attack with the pitchfork in addition to a melee attack. This arc contains spoilers for the Battle for Wesnoth campaign Eastern Invasion. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Mis Preguntas con Roberto Pombo
¿Qué tanto ha impactado la calvicie en el mundo?

Mis Preguntas con Roberto Pombo

Play Episode Listen Later Sep 29, 2024 28:42


La pérdida de pelo es un fenómeno cada vez más común. Para muchas personas esto significa un problema de autoestima y para otras es simplemente una característica física. ¿Qué tanto han aumentado las cirugías de trasplante de pelo?, ¿Se juzga más a las mujeres que a los hombres con alopecia?  Para este capítulo hablamos con Marie André Schambach, cirujana de restauración capilar y Tricóloga; con la periodista María Elvira Sámper; con el escritor Juan Esteban Constaín; con el dermatólogo Rodrigo Caicedo; y con el periodista Daniel Samper.

Dicey Stories
DS322 | Wesnoth | Echoes of Invasion: Old Haunts | Part 8 of 9

Dicey Stories

Play Episode Listen Later Sep 18, 2024 48:09


The elves and their allies clash with Godol the shadow mage and his. Scene 20 GM Notes Most of the NPCs in the fight today are units from the Battle for Wesnoth video game that we've already seen in earlier encounters, like Ruffians, Shadow Mages, and Efa the Bandit. The only new one here is Tric's merfolk friends, who are based on the Netcaster line. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS320 | Wesnoth | Echoes of Invasion: Old Haunts | Part 7 of 9

Dicey Stories

Play Episode Listen Later Sep 11, 2024 65:47


Rhaessa and Heledd join Tric and Heppa in their investigation of necromancers underneath South Tower. Scene 17 Scene 18 Scene 19 GM Notes The exploration of the space under South Tower was heavily inspired by combat maps from the Battle for Wesnoth video game. Cave terrain frequently has mushroom tiles, mining cart tracks, and old fortifications. And if you see a big stretch of water, you can be pretty sure a Tentacle of the Deep is lurking in it to attack any of your units that get too close! Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS318 | Wesnoth | Echoes of Invasion: Old Haunts | Part 6 of 9

Dicey Stories

Play Episode Listen Later Sep 4, 2024 56:56


Tric catches up some with Kachen and gets to know the new server at the Parting Glass. Scene 13 Scene 14 Scene 15 Scene 16 Note: This episode uses an adaptation of our Fight Night rules. Find them here. GM Notes In this episode, we finally get a scene that closely resembles our campaign artwork! When we commissioned the piece from Del Borovic the tableau was chosen simply to get a bunch of our major characters all together in a location that was important to us. It was six more months before I was able to orchestrate all the pieces coming together at the game table. The only inaccuracy is that Kachen has his staff in the illustration. Not too shabby, if I do say so myself. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS316 | Wesnoth | Echoes of Invasion: Old Haunts | Part 5 of 9

Dicey Stories

Play Episode Listen Later Aug 28, 2024 36:47


Tric recruits the white mage Rhaessa to help with whatever foul magics are afoot beneath South Tower. Scene 12 GM Notes In the Battle for Wesnoth video game, there are undead units whose attacks have the plague quality. Any unit killed by one of these rises again as a Walking Corpse—unless they were standing in a village when it happened. I've taken that video game mechanic and translated it into some more magical philosophy, to appease the constantly questioning Hepalonia. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS312 | Wesnoth | Echoes of Invasion: Old Haunts | Part 3 of 9

Dicey Stories

Play Episode Listen Later Aug 14, 2024 47:57


Tric and Heppa deal with a late night intruder. Scene 7 Scene 8 Scene 9 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS310 | Wesnoth | Echoes of Invasion: Old Haunts | Part 2 of 9

Dicey Stories

Play Episode Listen Later Aug 7, 2024 43:02


Tric reconnects with some of the Dunefok of South Tower, but neither his mother nor Damal are terribly impressed with him. Scene 4 Scene 5 Scene 6 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS306 | Wesnoth | Echoes of Invasion: Plains Problems | Part 7 of 7

Dicey Stories

Play Episode Listen Later Jul 24, 2024 35:36


Tric and Heppa bid farewell to Terwaen's household with several revealing conversations. Scene 15 Scene 16 Scene 17 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Ya sabes con Dermario
26 - Dra. Sara Cano, dermatóloga tricóloga . Todo sobre caída del pelo.

Ya sabes con Dermario

Play Episode Listen Later Jul 22, 2024 44:22


En este episodio hablamos con la experta colombiana en caída del cabello, causas de alopecia, el correcto aseo de la piel cabelluda, opciones de champú para caspa, mitos en el cuidado del pelo, procedimientos inyectables para estimular crecimiento capilar y muchas cosas más.

Dicey Stories
DS304 | Wesnoth | Echoes of Invasion: Plains Problems | Part 6 of 7

Dicey Stories

Play Episode Listen Later Jul 17, 2024 38:59


Tric duels Dame Merriver. Scene 14 Note: This episode uses our Fight Night rules. Find them here. GM Notes The Battle for Wesnoth video game inspired a lot of specific events and NPCs in our tabletop campaign. I leaned heavily on the closing events of the Eastern Invasion campaign, even quoting from the epilogue where Gweddry and Owaec are granted their rewards. But one specific part of the video game's lore that stood out to me was that the period after the war with Mal-Ravanal is considered Wesnoth's Silver Age—but it only lasts the length of King Konrad II's reign. Why did the Silver Age end? Why did Wesnoth fall to ruin again after that? Well, one outlandish theory from my players was that Konrad II had actually died long before history records it, and various nobles were keeping that a secret. That idea is what led to Merriver's righteous rage about the treatment of her father in court. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS302 | Wesnoth | Echoes of Invasion: Plains Problems | Part 5 of 7

Dicey Stories

Play Episode Listen Later Jul 10, 2024 49:54


Tric and Heppa talk with Dame Merriver about threats to the kingdom… and her illicit weapon shipments. Scene 13 Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Dicey Stories
DS300 | Wesnoth | Echoes of Invasion: Plains Problems | Part 4 of 7

Dicey Stories

Play Episode Listen Later Jul 3, 2024 38:08


Sir Anyc shows Tric and Heppa around and presents them to Dame Merriver. Scene 11 Scene 12 GM Notes Dame Merriver is a character we've had floating around our campaign from way, way back. All the rumors and theories about her is what inspired me to give her the special ability Ominous Reputation. She also has a theme song in my campaign playlist, which I would play on repeat while pondering what makes her tick. It's Ye Jacobites, specifically as performed by the group Scocha. The energy it has—the feeling of righteous anger at a political situation—fits her quite nicely. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Staying Relevant
82: Pete's TRIC Awards Took A Turn & Sam Responds To That Pap Photo

Staying Relevant

Play Episode Listen Later Jun 30, 2024 32:00


Sam and Pete have had a mega week with The TRIC Awards and Sam making the press with that viral pap shot. However - in classic Sam and Pete style, they didn't want to dwell on that, as there are some incredible things on the horizon, including The NTAs red carpet and Pete's inevitable decline into old age.Listen by clicking 'Play' on Apple Podcasts, Spotify, or wherever it is you're listening now.Make sure to Subscribe or Follow, Rate and Review to help others find the podcast. Follow us on Instagram & TikTok @stayingrelevantpodcast. Subscribe to us on YouTube @stayingrelevantpodcast.To get in touch with the podcast, email stayingrelevant@insanityhq.comStaying Relevant®, this has been an Insanity Studios production, in association with Bauer Media. Hosted on Acast. See acast.com/privacy for more information.

Dicey Stories
DS298 | Wesnoth | Echoes of Invasion: Plains Problems | Part 3 of 7

Dicey Stories

Play Episode Listen Later Jun 26, 2024 64:58


Tric and Heppa learn of some tensions within Terwaen's household… and within her people. Scene 7 Scene 8 Scene 9 Scene 10 GM Notes There are a number of mounted units in the Battle for Wesnoth video game. In preparation for this arc, I reviewed their descriptions and artwork for inspiration. Terwaen and Anyc are Knights, and Rugg and Inyc are Paladins. While not every unit type has an NPC in our game, there are still discussions of Grand Knights, Horsemen, and Lancers to give more flavor to the culture of the Horse Plains. And for orcish forces, the mounted units are the Wolf Rider line. Those are just talked about around the dinner table here, but don't worry, we'll see them eventually. Our character art by Del Borovic and the map we refer to (by me!) can be found here. Our music is sampled from Return to Wesnoth by Matthias Westlund (aka West), licensed under CC BY-SA 4.0, part of The Battle for Wesnoth Project. Visit them at wesnoth.org. Need context? Jump to the start of the series!

Staying Relevant
73: Sam Alone Is Nominated For A TRIC Award & Pete's Doing Stand-Up

Staying Relevant

Play Episode Listen Later May 5, 2024 32:06


The boys are back to business as normal now the tour is over and the staying relevant moments are back in full force. The podcast has been nominated for a TRIC Award but there seems to have been an admin error resulting in Pete being left out. But that's not all, as Sam and Pete made a visit to an agency meeting where Sam learnt a thing or two about sales.To vote for Sam and Staying Relevant to win at The TRIC Awards, CLICK HERE.Listen by clicking 'Play' on Apple Podcasts, Spotify, or wherever it is you're listening now.Make sure to Subscribe or Follow, Rate and Review to help others find the podcast. Follow us on Instagram & TikTok @stayingrelevantpodcast. Subscribe to us on YouTube @stayingrelevantpodcast.To get in touch with the podcast, email stayingrelevant@insanityhq.comStaying Relevant®, this has been an Insanity Studios production, in association with Bauer Media. Hosted on Acast. See acast.com/privacy for more information.

Avon Lake Matters
Avon Lake Matters - Interview with Avon Lake Recreation Director Erin Fach

Avon Lake Matters

Play Episode Listen Later Apr 12, 2024 25:40


Host Jen Miller is joined by Dr. Shauna Matelski, Interim and Acting CEO of Lorain County Community Action Agency, and talks about their programs for Lorain County residents, including Head Start and Pathways HUB. Upcoming events happening in Avon Lake: April 13, 5:00 PM: North Coast Rotary Foundation's "Sip & Support" Fundraiser at Tri-C's Westshore Campus in Westlake April 15, 7:00 PM: Combined City Council & Collective Committee Meeting April 16, 7:00 PM: Environmentally Speaking: Nurturing Trees for a Sustainable Future at the Avon Lake Public Library April 18-20, 7:00 PM & April 21, 2:00 PM: Avon Lake High School Drama Club Presents Disney's The Little Mermaid at the Avon Lake High School Performing Arts Center April 20, 9:00 AM: Test Drive a School Bus at the Avon Lake City Schools Bus Garage April 20, 6:30 PM: CRS's 35th Annual Charity Ball "A Community of Love" at The Shipyard Event Center in Lorain April 22, 7:00 PM: City Council Meeting April 25, 2:00 PM: 2024 Arbor Day Proclamation, Celebration, & Tree Plantings at the Avon Lake Safety Center April 25-26, 9:00 AM: Holy Spirit Ladies Guild Garage and Bake Sale at Holy Spirit Parish's Fr. Mosovsky Hall For information about these and future events/meetings in Avon Lake, please visit www.AvonLake.org/Events.

Revision Path
Kyra Wells

Revision Path

Play Episode Listen Later Jan 22, 2024 69:13


I've been a huge proponent of the Cleveland creative community since starting this podcast — seriously, go back to the early early episodes — and Kyra Wells is continuing the legacy of hard work, perseverance, and great design that only comes from the 216. Kyra is a true creative professional, whether it's through her own studio Seven Pillars Design Co., teaching at Cuyahoga Community College, leading campaigns as a creative marketing designer at American Greetings, or through her community efforts as co-president of AIGA Cleveland.We talked about both her day job and her freelance work, and she shared how both experiences have shaped her voice and find her calling as a designer. She also told her story of growing up in Cleveland, attending Tri-C before then going to Cleveland State University, and even spoke a bit about the role of AIGA for the modern designer.Kyra's enthusiasm and passion for supporting young designers and helping them overcome self-doubt is truly inspiring, so if you're looking for a little pep talk at the start of the year, then you're in the right place. Thanks to Anne H. Berry for the introduction!LinksKyra Wells' WebsiteKyra Wells on InstagramKyra Wells on LinkedInSeven Pillars Design Co.For a video of this interview, including a full transcript, visit revisionpath.com.==========Donate to Revision PathFor 10 years, Revision Path has been dedicated to showcasing Black designers and creatives from all over the world. In order to keep bringing you the content that you love, we need your support now more than ever.Click or tap here to make either a one-time or monthly donation to help keep Revision Path running strong.Thank you for your support!==========Follow and SubscribeLike this episode? Then subscribe to us on Apple Podcasts, Spotify, or wherever you find your favorite shows. Follow us, and leave us a 5-star rating and a review!==========CreditsRevision Path is brought to you by Lunch, a multidisciplinary creative studio in Atlanta, GA.Executive Producer and Host: Maurice CherryEditor and Audio Engineer: RJ BasilioIntro Voiceover: Music Man DreIntro and Outro Music: Yellow SpeakerThank you for listening!==========Sponsored by Brevity & WitBrevity & Wit is a strategy and design firm committed to designing a more inclusive and equitable world. They are always looking to expand their roster of freelance design consultants in the U.S., particularly brand strategists, copywriters, graphic designers and Web developers.If you know how to deliver excellent creative work reliably, and enjoy the autonomy of a virtual-based, freelance life (with no non-competes), check them out at brevityandwit.com.Brevity & Wit — creative excellence without the grind.==========Sponsored by the School of Visual Arts - BFA Design & BFA AdvertisingThe BFA Design program at the School of Visual Arts consistently produces innovative and acclaimed work that is rooted in a strong foundational understanding of visual communication. It encourages creativity through cutting-edge tools, visionary design techniques, and offers burgeoning creatives a space to find their voice.Students in BFA Advertising are prepared for success in the dynamic advertising industry in a program led by faculty from New York's top ad agencies. Situated at the center of the advertising capital of the world, the program inspires the next generation of creative thinkers and elite professionals to design the future.School of Visual Arts has been a leader in the education of artists, designers and creative professionals for over seven decades. Comprising 7,000 students at its Manhattan campus and more than 41,000 alumni from 128 countries, SVA also represents one of the most influential artistic communities in the world. For information about the College's 30 undergraduate and graduate degree programs, visit sva.edu.

Tricô de Pais
Uma Mensagem de Natal

Tricô de Pais

Play Episode Listen Later Dec 22, 2023 3:38


2024 está chegando ao fim, e está na hora de uma mensagem especial do Tricô!Calma, a gente não vai acabar, a gente só vai tirar férias mesmo. Menos o Queiroz, que tá lançando podcast nobo, o Pausa Pra Sentir. Depois confere lá, tá bem legal!Pausa Pra Sentir é um podcast que você encontra em todas as plataformas de podcast.Você pode contribuir para o Tricô a partir de R$10 na Orelo (orelo.cc/trico) - onde teremos conteúdos exclusivos para apoiadores!Produzido por Abrace Podcasts. Visite-nos em https://abrace.digital/