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Você sabe o que é uma Taenia e como ela afeta a saúde? Separe trinta minutinhos do seu dia e descubra, com a Mila Massuda, como esses parasitas se disseminam, quais riscos eles oferecem, as doenças relacionadas (teníase e cisticercose) e a importância de práticas adequadas de higiene e alimentação para a prevenção de infecções.
La paléoparasitologie est la science qui étudie les parasites dont on retrouve des traces dans un contexte archéologique ou paléontologique. Cette science pluridisciplinaire trouve des applications diverses et permet d'étudier l'état de santé, l'hygiène, la gestion des déchets, les modes de vie, l'alimentation, … des populations anciennes.Latrines du site de Saint-Germain-en-Laye (camp d'entrainement des troupes de Louis XIV)La recherche se porte principalement sur les helminthes, un groupe de vers parasites de l'être humain et de certains animaux. Le plus célèbre de ces helminthes est, sans doute, le fameux ver solitaire (principalement Taenia saginata ou Taenia solium).Céline est Docteure en archéologie, diplômée de l'Université Franche-Comté et chargée d'études au CNRS au sein de l'UMR 6249 : Chrono-Environnement. Elle fait partie de la seule équipe française de paléoparasitologie et étudie ces parasites, en particulier les helminthes, en contexte archéologique depuis sa thèse, soutenue en 2019, “Évolution des relations homme/parasite/environnement au Néolithique : approche intégrée et premiers essais de spatialisation sur les sites lacustres européens” dirigée par Hervé Richard et Matthieu Le Bailly. C'est donc une chance de recevoir, à mon micro, l'une des rares expertes françaises sur le sujet pour évoquer cette science méconnue et l'éclairage qu'elle peut apporter sur les questions liées à la santé de nos ancêtres.Retrouvez le site internet et les réseaux sociaux de l'Apothicast sur https://linktr.ee/apothicast !00:00 – Générique01:00 – Présentation de Céline Maicher et introduction02:25 – Parasitologie et parasitisme07:25 – La paléoparasitologie : définition11:29 – Quelques repères dans le temps15:04 – Le parcours de Céline Maicher16:37 – Une catégorie de parasites en particulier : les helminthes19:06 – Une mission type du paléoparasitologue23:04 – Paléoparasitologie et paléopathologies27:35 – Paléoparasitologie et régimes alimentaires30:05 – Paléoparasitologie et gestion des déchets32:53 – Paléoparasitologie et culture34:38 – Le cabinet de curiosités de l'Apothicast37:16 – Conclusion Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
We managed to make it through 2023 without a major epidemic or pandemic, and as we get into the holiday spirit and look forward to the new year, some of us took a look back and picked out one of our favorite JCM paper published in 2023, which I will tell you, was no easy task as there were many of good ones to choose from! And personally, after looking through all the issues over the last year, it never ceases to amaze me the variety of topics that we publish on in JCM – including unique things like the evaluation of a molecular assay for diagnosis of Buruli ulcers, to development of an EIA for detection of Taenia coproantigen, and then of course we have the more bread and butter things like evaluation of new assays for detection of TB resistance, to multiple studies this year on women's health diagnostics, and evaluation of new molecular assays for congenital CMV detection, and then I'm also told that there were some awesome AST-focused papers too, which is all just great. The four of us JCM editors have selected the following favorite papers of ours from the past year: Whole-Genome Subtyping Reveals Population Structure and Host Adaptation of Salmonella Typhimurium from Wild Birds | Journal of Clinical Microbiology (asm.org) Detailed β-(1→3)-D-glucan and mannan antigen kinetics in patients with candidemia | Journal of Clinical Microbiology (asm.org) Interlaboratory comparison of Pseudomonas aeruginosa phage susceptibility testing | Journal of Clinical Microbiology (asm.org) Emergence of Inducible Macrolide Resistance in Mycobacterium chelonae Due to Broad-Host-Range Plasmid and Chromosomal Variants of the Novel 23S rRNA Methylase Gene, erm(55) | Journal of Clinical Microbiology Commentary: Plasmid-mediated drug resistance in mycobacteria: the tip of the iceberg? | Journal of Clinical Microbiology Guests: Melissa Miller, Ph.D., D(ABMM), FAAM, University of North Carolina Medical Center Patricia Simner, Ph.D., D(ABMM), Johns Hopkins University School of Medicine This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. JCM is available at https://jcm.asm.org and on https://twitter.com/JClinMicro. Visit journals.asm.org/journal/jcm to read articles and/or submit a manuscript.
Ingrid og Jørgen snakker (mest) løst og (litt) fast om parasitter og vertskap. Fra zombiesoppen i serien "The last of us", drar vi på vandring videre gjennom noen av verdens (ekte) parasitter. Bli med på parasittekspedisjon! Referanser:1.Backman I. “The Last of Us” Apocalypse Is Not Realistic, But Rising Threat of Fungal Pathogens Is. Yale school of medicine - webpage. 2023.2.Del Brutto OH, Garcia HH. Taenia solium Cysticercosis--The lessons of history. J Neurol Sci. 2015;359(1-2):392-5.3.Hughes DP, Andersen SB, Hywel-Jones NL, Himaman W, Billen J, Boomsma JJ. Behavioral mechanisms and morphological symptoms of zombie ants dying from fungal infection. BMC Ecol. 2011;11:13.4.Kintzen W. The Caduceus Motif and The Guinea Worm. JAMA. 1968;203(3):234-.5.Pontoppidan MB, Himaman W, Hywel-Jones NL, Boomsma JJ, Hughes DP. Graveyards on the move: the spatio-temporal distribution of dead ophiocordyceps-infected ants. PLoS One. 2009;4(3):e4835.6.Rosania K. Tricking rats into liking cats. Lab Anim (NY). 2011;40(10):288.7.Saevik BK, Krontveit RI, Eggen KP, Malmberg N, Thoresen SI, Prestrud KW. Toxoplasma gondii seroprevalence in pet cats in Norway and risk factors for seropositivity. J Feline Med Surg. 2015;17(12):1049-56.8.Webster JP. Rats, cats, people and parasites: the impact of latent toxoplasmosis on behaviour. Microbes Infect. 2001;3(12):1037-45.9.Wilcox RA, Whitham EM. The symbol of modern medicine: why one snake is more than two. Ann Intern Med. 2003;138(8):673-710 Save the guinea-worm-foundation: http://www.deadlysins.com/guinea-worm11 Ophiocordyceps unilateralis - Wikipedia Hosted on Acast. See acast.com/privacy for more information.
Neurocysticercosis - an infection of the brain by a pork tapeworm (Taenia solium) – is one of the most common causes of seizures worldwide. People with neurocysticercosis have incidentally ingested tapeworm eggs, which are found in the feces of people who have tapeworms in their digestive systems (a condition called taeniasis). The eggs can migrate to any organ and form larval cysts; the brain is one of the most common sites.Pigs are intermediate hosts, so neurocysticercosis occurs in regions where humans live in close contact with pigs and eat undercooked pork. Poor sanitation that leads to environmental fecal contamination is a major factor in transmission. Selected publications from the Cysticercosis Working Group in Peru:Quality of life in patients with symptomatic epilepsy due to neurocysticercosis (2022)New animal models of neurocysticercosis can help understand epileptogenesis in neuroinfection (2022)Geographically targeted interventions versus mass drug administration to control Taenia solium cysticercosis in Peru (2021)Current diagnostic criteria for neurocysticercosis (2021)Neurocysticercosis: A frequent cause of seizures, epilepsy, and other neurological morbidity in most of the world (2021) The International League Against Epilepsy invites you to explore the ILAE Academy: Interactive, practice based online courses for health care professionals who diagnose and treat epilepsy. Find more information at ilae-academy.org. Support the showSharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Twitter, and Instagram.
Coenurosis is a disease of the central nervous system in sheep, caused by Coenurus cerebralis, the larval stage of Taenia multiceps, a tapeworm, which infests the small intestine of carnivores.
Waspada! Cacing Pita Mengintai Kita Oleh. drh. Lailatus Sa'diyah (Kontributor Tetap NarasiPost.Com) Voice over talent: Dewi Nasjag NarasiPost.Com-Cacing adalah salah satu hewan yang sering kita temui dalam kehidupan. Bahkan, tidak jarang pula kita temui pada usus hewan ternak sebagai asal bahan pangan, ataupun pada organ lainnya. Tapi tahukah Sahabat NarasiPost.Com, bahwa ada beberapa jenis cacing pada hewan yang bisa menginfeksi tubuh kita? Iya, salah satunya adalah cacing pita. Infeksi cacing pita merupakan kondisi yang biasa disebut taeniasis. Cacing pita adalah sejenis cacing parasit yang berbentuk pipih. Beberapa dari spesies ini dapat menginfeksi manusia. Infeksi lebih sering terjadi pada suatu daerah di mana fasilitas sanitasi kurang baik atau karena adanya kontak dekat dengan hewan terinfeksi. Adanya penularan penyakit asal hewan ke manusia disebut zoonosis. Perlu digaris bawahi, bahwa tidak semua penyakit asal hewan adalah zoonosis, namun penyakit yang bisa menular dari hewan ke manusia atau sebaliknya dikategorikan sebagai penyakit zoonosis. Kepala cacing pita dilihat dari microscop Infeksi cacing pita pada manusia acapkali diakibatkan makan daging sapi, babi, atau ikan yang kurang matang atau mentah dari hewan yang terinfeksi. Spesies cacing pita yang berasal dari daging babi adalah Taenia solium dan spesies yang ditemukan pada daging sapi adalah Taenia saginata (merdeka.com, 01/03/2021) Naskah selengkapnya: https://narasipost.com/2022/05/25/waspada-cacing-pita-mengintai-kita/ Terimakasih buat kalian yang sudah mendengarkan podcast ini, Follow us on: instagram: http://instagram.com/narasipost Facebook: https://www.facebook.com/narasi.post.9 Fanpage: Https://www.facebook.com/pg/narasipostmedia/posts/ Twitter: Http://twitter.com/narasipost
**Major Trigger Warning for anyone with gross body horror and fear of parasites.** This week we're discussing parasites--mostly tapeworms-- but we'll touch on roundworms, heartworms and (not a worm) ringworms. Join us on this horrifying and truly disgusting journey if you dare. Not sponsored, but Heath and Danielle use this website to get inexpensive flea, tick, and heartworm prevention. We hope it helps you also. https://www.budgetpetcare.com/ Sources: https://www.cdc.gov/parasites/taeniasis/gen_info/faqs.html https://animaldiversity.org/accounts/Taenia_taeniaeformis/ https://en.wikipedia.org/wiki/Taenia_pisiformis https://www.sciencedirect.com/topics/immunology-and-microbiology/taenia-pisiformis https://www.britannica.com/science/polymerization https://vcahospitals.com/know-your-pet/tapeworm-infection-in-cats https://healthfacts.blog/2018/01/19/what-is-the-longest-tapeworm-ever-removed-from-a-person https://www.livescience.com/53598-tapeworms.html
Dr. Seth O'Neal, an associate professor of epidemiology at Oregon Health & Science University in Portland, Oregon, and Sarah Gregory discuss control strategies for Taenia solium cysticercosis in people and pigs in Peru.
SÉRIE - "Minuto da Prevenção" TEMA - PARASITOSES Produzidos pelos discentes do Projeto da Escola Técnica de Saúde da UFPB.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.26.314567v1?rss=1 Authors: Van Belle, S. C., de Lange, A., Tomes, H., Lucas, R., Naidoo, V., Raimondo, J. V. Abstract: Human cysticercosis is a disease caused by larvae of the cestode Taenia solium. It is the most common cause of adult-acquired epilepsy world-wide where it exacts a debilitating toll on the health and well-being of affected communities. It is commonly assumed that the major symptoms associated with cysticercosis are a result of the direct presence of larvae in the brain. As a result, the possible effect of peripherally located larvae on the central nervous system are not well understood. To address this question, we utilised the Taenia crassiceps intra-peritoneal murine model of cysticercosis, where larvae are restricted to the peritoneal cavity. In this model, previous research has observed behavioural changes in rodents but not the development of seizures. Here we used ELISAs, immunoblotting and the Evans Blue test for blood-brain barrier permeability to explore the central effects of peripheral infection of mice with Taenia crassiceps. We identified high levels of parasite-targeting immunoglobulins in the serum of Taenia crassiceps infected mice. We show that the Taenia crassciceps larvae themselves also contain and release host immunoglobulins over time. Additionally, we describe, for the first time, significantly increased levels of IgG within the hippocampi of infected mice, which are accompanied by changes in blood-brain barrier permeability. However, these Taenia crassiceps induced changes were not accompanied by alterations to the levels of proinflammatory, pro-seizure cytokines in the hippocampus. These findings contribute to the understanding of systemic and neuroimmune responses in the Taenia crassiceps model of cysticercosis, with implications for the pathogenesis of human cysticercosis. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.12.148007v1?rss=1 Authors: de Lange, A., Prodjinotho, F., Tomes, H., Hagen, J., Jacobs, B.-A., Smith, K., Horsnell, W., Sikasunge, C., Selkirk, M. E., Prazeres da Costa, C., Raimondo, J. V. Abstract: Larvae of the cestodes Taenia solium and Taenia crassiceps infect the central nervous system of humans. Taenia solium larvae in the brain cause neurocysticercosis, the leading cause of adult-acquired epilepsy worldwide. Relatively little is understood about how cestode-derived products modulate host neural and immune signalling. Acetylcholinesterases, a class of enzyme that degrade acetylcholine, are produced by a host of parasitic worms to aid their survival in the host. Acetylcholine is an important signalling molecule in both the human nervous and immune systems, with powerful modulatory effects on the excitability of cortical networks. Therefore, it is important to establish whether cestode derived acetylcholinesterases may alter host neuronal cholinergic signalling. Here we make use of multiple techniques to profile acetylcholinesterase activity in different extracts of both Taenia crassiceps and Taenia solium larvae. We find that the larvae of both species contain substantial acetylcholinesterase activity. However, acetylcholinesterase activity is lower in Taenia solium as compared to Taenia crassiceps larvae. Further, whilst we observed acetylcholinesterase activity in all fractions of Taenia crassiceps larvae, including on the membrane surface and in the excreted/secreted extracts, we could not identify acetylcholinesterases on the membrane surface or in the excreted/secreted extracts of Taenia solium larvae. Finally, using whole-cell patch clamp recordings in rat hippocampal brain slice cultures, we demonstrate that Taenia larval derived acetylcholinesterases can modify neuronal responses to acetylcholine. Together, these findings highlight the possibility that Taenia larval acetylcholinesterases can interfere with cholinergic signalling in the host, potentially contributing to pathogenesis in neurocysticercosis. Copy rights belong to original authors. Visit the link for more info
Bugs are Coming! Safe Products for Breeding Dogs + CoronavirusDr. Marty Greer brings her pragmatic Veterinary Voice to the topic of Coronavirus and what products are safe to use for flea, tick and heartworm prevention in breeding dogs. COVID-19 is not currently believed to be communicable between humans and dogs. Coronavirus is a general term for a *shape* of a virus and encompasses a variety of viral infections in many species. For more information on recommendations regarding veterinary care during this outbreak, click https://www.foxrothschild.com/publications/coronavirus-response-plans-for-veterinary-practices/ (here). As spring brings the reemergence of various creepy, crawly parasites that affect our dogs, Greer provides in-depth information about which products are safe for use on dogs in our breeding programs, including brood bitches and stud dogs over the course of time, as well as bitches in whelp. Greer said, “I think it's really appropriate for us to stick to the EPA and FDA approved drugs that we know have been tested and safe in breeding animals. So, for instance, Bravecto says there were no clinically relevant treatment-related effects on body weights, food consumption, reproductive performance, semen analysis, litter data, gross necropsy or Histology findings in adults and puppies. So we need to be looking for that kind of language on a label before we go slapping things on or popping things into our dogs … I just want to be perfectly clear for what products have or have not been tested. "So there's three basic categories of flea and tick medications. There's the collar, there's the topical, the oil that goes over the back of the neck or down the back and there's the tablets or the chewables. So there are the three general categories and of those three there's no collar …. labeled for that use in breeding dogs … the topicals, some are definitely labeled and some are not definitely labeled. …if it says like Frontline says safe for breeding, pregnant and lactating dogs and cats, then it's safe. If it doesn't say that you shouldn't use it. It needs to be clear. And if we look at the oral there's …. three oral medications that are not labeled for use in breeding animals. Bravecto is labeled for use in breeding animals. So we need to be really, really clear that we're looking at the labels or reading the instructions and we're thinking at eight weeks of age, what is the this dog’s future, not just is she pregnant right now, but what is her future.” Product Active Ingredients Purpose/Effective Against Minimum Age/Weight Pregnant/Nursing/Male Heartworm Advantage Multi for Dogs Imidacloprid and moxidectin Flea, louse, heartworm, hookworm, whipworm, roundworm and mange. Topical every 30 days 7 weeks/3lbs Safety not established. Advantage Multi for Cats Imidacloprid and moxidectin Ear mites, flea, heartworm, hookworm and roundworm. Topical every 30 days 9 weeks/2 lbs Safety not established. Heartgard Plus Ivermectin,Pyrantel pamoate Heartworm, roundworms & hookworms Tablet every 30 days 6 weeks Safe in pregnant or breeding bitches, stud dogs Heartgard Ivermectin Dog: Heartworm. Tablet every 30 daysCat: Heartworm and hookworm. Tablet every 30 days 6 weeks Safe Interceptor Milbemycin oxime Heartworm, hookworm, whipworm, roundworm. Every 30 days Dog: 4 weeks/2 lbsCat: 6 weeks/1.5lbs Dogs: SafeCat: Not established Interceptor Plus Milbemycin oxime and praziquantel tablet Heartworm, roundworm (Toxocara canis, Toxascaris leonina), adult hookworm (Ancylostoma caninum), adult whipworm (Trichuris vulpis), and adult tapeworm (Taenia pisiformis, Echinococcus multilocularis and Echinococcus granulosus) Tablet every 30 days Dogs and puppies 2 pounds of body weight or greater and 6 weeks of age and older. SafeNot evaluated in breeding, pregnant or lactating dogs. Only milbemycin has been studied and is safe. Iverhart Max Ivermectin,Pyrantel pamoate,... Support this podcast
Taenia solium is a tapeworm that people get from eating raw or undercooked “measly pork”. The pork meat has cysticerci (the larval stage) which in the human intestine mature to an adult tapeworm. Here the tapeworm attaches to the intestine and produces thousands of eggs. Human cysticercosis occurs either by the direct transfer of Taenia solium eggs from the feces of people harboring an adult worm to their own mouth (autoinfection) or to the mouth of another individual, or indirectly by ingestion of food or water contaminated with the eggs. When the person ingests the eggs, the embryo escape from the shell and penetrates the intestinal wall, gets into the blood vessels, where they spread to muscle, or more seriously, the eyes, heart or brain. Parasitology teacher and author of the book Parasites: Tales of Humanity's Most Unwelcome Guests, Rosemary Drisdelle joins to discuss the cestode.
Taenia solium is a tapeworm that people get from eating raw or undercooked “measly pork”. The pork meat has cysticerci (the larval stage) which in the human intestine mature to an adult tapeworm. Here the tapeworm attaches to the intestine and produces thousands of eggs. Human cysticercosis occurs either by the direct transfer of Taenia […] The post Pork tapeworm and cysticercosis appeared first on Outbreak News Today.
Taeniasis is a parasitic disease due to infection with tapeworms belonging to the genus Taenia. Three tapeworm species cause taeniasis in humans, Taenia solium, Taenia saginata and Taenia asiatica. On today's show, I will be talking to my guest, Parasitology teacher, author and friend of the show, Rosemary Drisdelle about the beef tapeworm, Taenia saginata.
Taeniasis is a parasitic disease due to infection with tapeworms belonging to the genus Taenia. Three tapeworm species cause taeniasis in humans, Taenia solium, Taenia saginata and Taenia asiatica. On today’s show, I will be talking to my guest, Parasitology teacher, author and friend of the show, Rosemary Drisdelle about the beef tapeworm, Taenia saginata. Parasites: Tales of Humanity’s […] The post Taenia saginata: The beef tapeworm appeared first on Outbreak News Today.
In this podcast, I pulled out a radio interview from the 4th of July 2016 weekend where the discussion was on foodborne parasites found in the United States. I was joined by microbiologist and the man behind the website, Parasitology Illustrated, Wilson Vientos. We spent at least a half hour talking about the Centers for Disease Control and Prevention's (CDC) list of the top foodborne (and may are primarily waterborne) parasites in the United States– protozoa such as Cryptosporidium spp.,Giardia intestinalis, Cyclospora cayetanensis, and Toxoplasma gondii; roundworms such as Trichinella spp. and Anisakis spp.; and tapeworms such as Diphyllobothrium spp. and Taenia spp.
The TWiPtoids solve the case of the Man from India with a Neck Lump, and explore the role of a transmissible dysbiotic skin microbiome in inflammation during cutaneous leishmaniasis. Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin Become a patron of TWiP. Links for this episode: Transmissible dysbiotic skin microbiome in cutaneous leishmaniasis (Cell Host Microbe) Letters read on TWiP 137 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get 3 meals free with your first purchase – WITH FREE SHIPPING – by going to blueapron.com/twip. Case Study for TWiP 137 Little town in DR, fall of 2016, have already mentioned this patient; little boy 2-3 years old, not behaving well, warned if doesn’t behave, los gusanos will eat you! Mother asks Daniel to help son: lately is more irritable, troublesome, not well behaved; notices things in his hair. Has small poppy seed sized things on side of hair shafts. She picks them off in fingers and smashes them. What are they, what do I do? Simple dwelling, dirt floor, walls and tin roof, animals everywhere. No money for medicines, what can she do? Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin Guest: Jason Zucker The TWiP ternion solve the case of the Man from Mexico, and discuss a transgenic toxoplasma vaccine for chickens using Eimeria tenella. Links for this episode: Transgenic Eimeria as a toxoplasma vaccine (Sci Rep) Image shows cysticercus of T. solium in brain (Parasitic Diseases, 5th Ed) Letters read on TWiP 113 This episode is sponsored by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and nonfiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE. Become a patron of TWiP. Case Study for TWiP 113 22 yo female comes to clinic in Bronx, reports one week of vaginal discharge and itching. Looks bad, yellowish. Sexually active with boyfriend. He has no symptoms. Some discomfort on urination. Healthy, no prior surgeries, no allergies. Mother with diabetes, father has high bp. Takes oral contraceptive pills. Not employed, lives with mother and sisters. Substance abuse: some on occasion, marijuana and alcohol, no i.v. No pets. Diet: lot of fast food. Physical exam: slightly heavy, normal but vaginal exam: discharge, thick, slight yellow light green color, no strong odor, some redness to vaginal walls, no changes to cervix. 2 weeks from last menstrual period. Send your case diagnosis, questions and comments to twip@microbe.tv
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin The doctors TWiP solve the case of the Woman with White Worms, and explain the role of a secreted growth factor from a carcinogenic parasite in wound healing and angiogenesis. Links for this episode: Wound healing growth factor from carcinogenic parasite (PLoS Path) Opisthorchis (CDC) Opisthorchis life cycle (CDC) Image credit Letters read on TWiP 101 Listener Pick Ramon - Ancient Rome was infested with parasites Case study for TWiP 101 This week's case involves an uncommon parasite. Young girl,
Vincent, Dickson, and Daniel reveal last week's case study and introduce a new one concerning a patient who traveled to Belize. Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin Links for this episode: Neurocysticercosis (TWiP 6) Cysticercosis (CDC) Sarah Lane's neurocysticercosis Letters read on TWiP 89 Contact Send your questions and comments (email or mp3 file) to twip@twiv.tv Subscribe Subscribe to TWiP (free) in iTunes, by the RSS feed or by email
Vincent and Dick talk about the anatomy and life cycle of beef and pork tapeworms, and why House was wrong about neurocysticercosis. Host links: Vincent Racaniello and Dickson Despommier Links for this episode: Taenia saginata life cycle (jpg) Taenia saginata adult (jpg) Taenia saginata scolex (jpg) Taenia saginata gravid proglottid (jpg) Taenia solium life cycle (jpg) Taenia solium adult (jpg) Taenia solium scolex (jpg) Facial cancer in Tasmanian devils (thanks PhogDog!) Science Picks Dickson Peace through vaccine diplomacy by Peter HotezVincent Parasite Rex by Carl Zimmer
Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-4 or IL-13. In mice, peritoneal M2 macrophages, elicited during infection with the parasites Taenia crassiceps or Tryponosoma brucei brucei, expressed increased CD200R levels compared to those derived from uninfected mice. However, in vitro stimulation of mouse peritoneal macrophages and T crassiceps infection in IL-4-/- and IL-4R-/- mice showed that, in contrast to humans, induction of CD200R in mice was not IL-4 or IL-13 dependent. Our data identify CD200R as a suitable marker for alternatively activated macrophages in humans and corroborate observations of distinct species- and/or site-specific mechanisms regulating macrophage polarization in mouse and man. Copyright (C) 2009 S. Karger AG, Basel
Tierärztliche Fakultät - Digitale Hochschulschriften der LMU - Teil 03/07
Im Rahmen dieser Arbeit wurden 223 Aufbrüche von erlegten Gämsen (43 Kitze; 76 Stücke der Jugendklasse: Böcke 1-2 Jahre, Geißen 1-3 Jahre; 85 Stücke der Mittelklasse: Böcke 3-7 Jahre, Geißen 4-9 Jahre; 19 Stücke der Altenklasse: Böcke ≥ 8 Jahre, Geißen ≥ 10 Jahre; 130 Böcke, 91 Geißen, 2 Stücke ohne Angabe des Geschlechts) parasitologisch untersucht. Dabei stammten 185 Tiere aus Bayern (Bayerische Alpen) und 38 aus Baden-Württemberg (Schwarzwald). Das Untersuchungsmaterial bestand aus den kompletten Magen-Darm-Kanälen (Pansen, Labmagen, Dünndarm, Dickdarm) der Gämsen und wurde in den Jahren 2004, 2005 und 2006 gesammelt. Die Untersuchung der Enddarmkotproben (n = 223) ergab folgende Ausscheidungsextensitäten von Entwicklungsstadien von Magen-Darm-Helminthen: Strongyliden-Eier, 74%; Nematodirus/Marshallagia-Eier, 22%; Trichuris-Eier, 10,8%; Moniezia-Eier, 9,4%; Capillaria-Eier, 6,3%. Die Labmägen waren zu 100%, Dünn- und Dickdärme zu 88% bzw. 79% mit Nematoden befallen; in den Pansen waren Parasiten nicht nachweisbar. Im Labmagen sind durchschnittlich (geometrisches Mittel) 588 Nematoden/Tier gezählt worden, in Dünn- und Dickdarm betrugen die Wurmbürden 36 bzw. 8 Exemplare/Gämse. Der individuelle Wurmbefall variierte zwischen 29 und 6932 Nematoden, wobei über die Hälfte der Gämsen mit weniger als 1000 Magen-Darm-Nematoden befallen waren. Durch die parasitologische Sektion wurden insgesamt 29 Nematodenarten im Magen-Darm-Kanal der Gämsen festgestellt. Mit Prävalenzen von ≥50% sind Ostertagia (O.) circumcincta, Marshallagia marshalli, O. trifurcata, Oesophagostomum venulosum, Grosspiculagia occidentalis, Haemonchus contortus, O. pinnata, Nematodirus (N.) filicollis, mit Befallsextensitäten von ≥20 bis