Podcasts about Histology

In this episode, Naim Alkhouri, Mike Betel, Michelle Long and Jeff McIntyre join Jörn Schattenberg and Roger Green to look back at The Liver Meeting 2024. This conversation reviews the late-breaker presentation on efimosermin, a q4w FGF-21 agent and the "FDA Corner" session. Jörn begins the discussion by highlighting a paper from the later breaker session on efimosfermin alfa, an FGF-21 agent dosed q4w. He notes that after only six doses (24 weeks), efimosfermin alfa demonstrated significant increases in fibrosis regression and lowering NAS score. To Jörn, this result, coupled with others on efruxifermin and pegozafermin, suggest that FGF-21s are likely to play a significant role in MASH therapy once approved. After Roger and Mike note their enthusiasm about the drug class and this study, Jörn mentions a study with 96-week efruxifermin that data demonstrates prolonged efficacy. As he points out, this matters because while studies of an earlier FGF-21 candidate suggested that antibodies might develop in FGF-21 therapy, that does not appear to be an issue here. Mike asks the group why they feel placebo performs so well in clinical trials. Jörn suggests that working with a compassionate clinical care team in dealing with the patient leads to better performance on diet and exercise and, as a result, increased placebo response to what we might find in general community practice.Michelle praises the FDA Corner session, particularly the agency's transparency and willingness to engage industry and academia in finding paths to move away from biopsy. She also notes some of the practical challenges inherent of moving away from biopsy using data from earlier trials with an outmoded histology reader setup. She is optimistic about the scientific community coming together to address these issues. Jeff praises the agency for an "amazing" session. 

Epithelium is one of the four basic tissue types (the other three are muscle tissue, nerve tissue, and connective tissue). It is found throughout the body—covering it; lining organs, vessels, and cavities; and forming glands. It absorbs nutrients, transports electrolytes, secretes hormones, and regulates body temperature by producing sweat. We begin with some general principles of how epithelial tissue is organized, and then we describe its various components. After listening to this AudioBrick, you should be able to: List the two types of epithelium (covering/lining and glandular) and describe their functions. Describe the structure and histologic features of epithelial tissue. Explain how covering/lining epithelium is classified. Describe the histologic features of glandular epithelium. Describe the five types of epithelial intercellular junctions. You can also check out the original brick on the Histology of Epithelial Tissue from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks.  After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology. *** If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts.  It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/

CardioNerds (Amit Goyal) join Dr. Merna Hussien, Dr. Akhil Kallur, Dr. Abhinav Saxena, and Dr. Brody Deb from the MedStar Georgetown - Washington Hospital Center in DC for a stroll around Rock Creek Park as they discuss an unusual case of cobalt cardiomyopathy. Expert commentary is provided by Dr. Nana Afari Armah. Episode audio was edited by CardioNerds Intern Christiana Dangas. The case is of a middle-aged woman with a past medical history of hypertension, hyperlipidemia, and bilateral hip replacements, who presented with subacute progressive exertional dyspnea, orthopnea, and constitutional symptoms and was found to have SCAI Stage C cardiogenic shock. Transthoracic echocardiogram showed severely reduced left ventricular ejection fraction (LVEF, 20-25%) and a moderate pericardial effusion. Cardiac catheterization revealed biventricular failure with elevated filling pressures. A cardiac MRI showed diffuse late gadolinium enhancement (LGE) in the left ventricle. Endomyocardial biopsy showed nonspecific chronic inflammation. However, the evidence of mitochondrial heavy metal toxicity and elevated cobalt levels made the diagnosis of cobalt cardiomyopathy. The patient underwent revision of hip joint implants to ceramic implants and started chelation therapy. However, due to persistent stage D heart failure despite normalization of cobalt levels, she underwent orthotropic heart transplantation. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Case MEdia - Cobalt Cardiomyopathy Pearls - Cobalt Cardiomyopathy A good history goes a long way in diagnosing non-ischemic cardiomyopathy (NICM). Common problems can have uncommon presentations requiring a high degree of suspicion for diagnosis. Imaging features can overlap between causes of NICM. History helps in targeting further histological workup and uncovering the root cause. Multidisciplinary effort is essential in making a rare diagnosis. Taken from1 - Singh M, Krishnan M, Ghazzal A, Halushka M, Tozzi JE, Bunning RD, Rodrigo ME, Najjar SS, Molina EJ, Sheikh FH. From Hip to Heart: A Comprehensive Evaluation of an Infiltrative Cardiomyopathy. CJC Open. 2021 Nov 1;3(11):1392–5. Notes - Cobalt Cardiomyopathy How common is cobalt cardiomyopathy? When should it be suspected? Cobalt cardiomyopathy is incredibly rare, with only a handful of reported cases. 2 It is also known as beer drinkers' cardiomyopathy, as cobalt was added to beer for fortification in Quebec 3, where it was first reported. Cobalt cardiomyopathy is characterized by its rapidly progressive nature, the presence of low voltages on EKG, and diffuse infiltration. Patients also complained of a previous history of anorexia and weight loss and were found to have polycythemia and thyroid abnormalities on labs. This syndrome was very similar to wet beriberi except for the absence of a therapeutic response to thiamine. Taken from - 2 Later, this was noted in patients with total metal hip arthroplasty 4–6, especially in patients with metal-on-metal hip arthroplasty, which led to corrosion and leakage of cobalt into the bloodstream. The syndrome in these patients was similar to those in beer drinkers from Quebec. This figure, taken from 2, shows the reports of Cobalt cardiomyopathy after cobalt alloy prostheses. [HX1]  What is the pathophysiology of cobalt cardiomyopathy? Cobalt has a variety of effects on the heart, both microscopically and biochemically.Cobalt may have multiple calcium-mediated cardiac effects and may also interfere with the Krebs cycle and ATP generation by mitochondria. Histology may show modest changes with no inflammatory response o...

This conversation contains the first half of Roger Green's interview with PharmaNest Founder and CEO Mathieu Petitjean. After Matt tells the audience a little about his background and PhramaNest, the two discuss what Matt considered the key strategic takeaways for PharmaNest from the various EASL Congress presentations, abstracts and discussions. Before answering the question, Matt describes the core services his company offers: "PharmaNest specializes in digital pathology. Four years ago, we put down the hypothesis that the histological phenotype of fibrosis should be quantified in a high-resolution, sophisticated way." He goes on to state their core proposition for MASLD: "The big idea here is that fibrosis equals phenotype." He proceeds to describe his offerings in greater detail before offering the underlying value of computed histology: fibrosis is a continuous variable that is scored in discrete categories under the NASH-CRN model that drives FDA analysis. With this as context, he answers the question by describing three kinds of MASLD clinical trial designs. The first, earliest trials had a single pathologist reading histological slides. The method is not precise, but the drugs were not very good, and none were ultimately approved. The second set of trials relied on more rigorous methods for pathologists to read histology slides, with multiple readers and robust adjudication systems. Also, the drugs in this second set of trials were more efficacious, so that NASH-CRN, while a blunt instrument, could adequately assess efficacy. For the third set of trials, Matt believes non-invasive tests (NITs) are likely to suffice.

Some headbutting animals suffer brain damage from the shock; Plus Mississippi has a new most complete dinosaur; Histology can help tell a dinosaur fossil from other dinosaurs; and more.For links to every news story, all of the details we shared about Saurornithoides, and our fun fact check out https://iknowdino.com/Saurornithoides-Episode-505/Join us at www.patreon.com/iknowdino for dinosaur requests, bonus content, ad-free episodes, and more.Dinosaur of the day Saurornithoides, a troodontid from Mongolia named in 1924 by Osborn in the same paper as Velociraptor.In dinosaur news this week:Paleontologists reviewed what it means to have a dome-head and to headbutt like a pachycephalosaurid (and other prehistoric animals)Mississippi has a new most complete dinosaur, but the species is still a mysteryHistology can tell us if a fossil belonged to a dinosaur or another type of animals This episode is brought to you by Brilliant.org They have courses that can help you better understand the latest developments in paleontology. From chemistry which underlies the fossilization process to data science that is used to model dinosaur populations. Start your 30-day free trial today! Plus I Know Dino subscribers can get an extra 20% off a premium annual subscription at Brilliant.org/iknowdinoNL/You can win a large Spinosaurus tooth, fossilized leaf, and more by winning our Di-Know-It-All Challenge! Each week from episode 502 to 509 we'll read a puzzle on the show which you can enter to win by answering questions. This week you can enter at bit.ly/dinochallenge505 and if you're a patron you can answer the patron question at patreon.com/posts/108019451. All the rules for the challenge are at bit.ly/dinochallenge24See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In the cosy environment of the University Campus Library and a friendly atmosphere over coffee and breakfast, a discussion took place between Vice Dean Tomáš Kašpárek and scientists Tomáš Bárta and Aleš Hampl from the Institute of Histology and Embryology about their beginnings in their work, important moments in their scientific careers and the people who influenced them the most. The guests recalled their experiences in foreign laboratories and compared the scientific world at the beginning of their research careers with today's world.

From mysteriously losing 4 hours of time while driving, to your indoor dog somehow appearing outside when you least expect it. These disturbing stories will take you on an exploration through the world of real life glitches, and will leave you with a sense of relaxation and calm. It's equal parts unsettling, and relaxing. Maybe its the fact that Glitch in the Matrix stories are so relatable, maybe its the spooky rain ambience in the background, or it could be the narrator's calming voice. Why do YOU like these hearing these encounters? If you have a story you want to submit, email it to DarekWeberSubmissions@gmail.com

Today, you'll hear straight from a dental hygiene school professor! Everything from studying tips to managing stress while in dental hygiene school. This episode shares advice to help get you through school. We touch on finding patients, mental health, imposter syndrome and more. Even if you are half way through the program, you will still benefit from this episode. Melissa Calhoun, a 2005 graduate of Pensacola State College's dental hygiene program, is a distinguished professional with extensive experience in pediatric, implant, and general dentistry. In 2021, she earned her master's in dental hygiene with an education focus from MCPHS University. Based in Keller, TX, Melissa is an educator at Tarrant County College in their Dental Hygiene Department, where she teaches Radiology, Oral Anatomy and Histology, and Pharmacology. Melissa is also a clinician, a faculty member with Sanders Board Preparatory, a professional educator with Church and Dwight, and an SDA trainer with EMS Dental. In leadership roles, she serves as the President-Elect of the American Academy of Dental Hygiene. Melissa's dynamic contributions highlight her commitment to advancing oral health education and professional growth. The AADH (American Academy of Dental Hygiene) has not begun accepting student membership yet. I encourage students to join our emailing list (LINK HERE ) to be the first to learn when registration begins. Once they accept students, the mentorship program will be opened to them. Contact Melissa: mcalhounrdh@icloud.com Additional recommended episodes: 54. Hygiene School Advice 32. Pressure of Hygiene School 25. Navigating Hygiene School 22. Managing Hygiene School 12. Working While in Dental Hygiene School 3. Finding Patients 2. Six Tips for Starting Dental Hygiene School

In this episode of Lung Cancer Considered, host Dr. Narjust Florez moderates a discussion about adenosquamous cell carcinoma of the lung, from diagnosis, treatment, and outcomes in this group of patients.

If only Gary Glitter hadn't done that one thing that he did repeatedly.  Intro Music: Gary Glitter- Hello, Hello I'm Back Again! https://demolisten.bigcartel.com/product/a-i-d-s-maleficus-sabbatum  Submit music to demolistenpodcast@gmail.com. Become a patron at https://www.patreon.com/demolistenpodcast. Leave us a message at (260)222-8341 Queue: Take It In Blood, Seudo Youth, Dynamite, Carcinogen, Histology, The Dogs, Righteous Propaganda, Superviolet, Iron Ghost, Gangstalker https://qualitycontrolhq.bandcamp.com/album/roadmap-of-pain https://www.youtube.com/watch?v=35ByrnbMNeY https://qualitycontrolhq.bandcamp.com/album/blow-the-bloody-doors-off https://limitedhangoutrecs.bandcamp.com/album/demo https://histologist.bandcamp.com/album/histology-of-the-cardiovascular-system https://thedogspunk.bandcamp.com/album/dog-shit https://rsrhap.bandcamp.com/album/righteous-propaganda-lathe-cut-9  

Dr Shane is joined by EAGG regulars Dr Suzi, Chris KP and Dr Scarlett, Alongside them this week are 3 amazing guests. Dr Chris Freelance Biologist, Science communicator and Manager of the Melbourne Histology Platform, shares insight into Histology and the research and analysis underway examining microanatomy.Jacinda O'Connor PhD Student – Monash University, discusses the Securing Antarctica's Environmental Future (SAEF) project, and data surrounding climate change related rising sea levels.Dr Samantha Mooney Obstetrician and Gynaecologist from the Julia Argyrou Endometriosis Centre at Epworth, discusses Endometriosis and an important upcoming Endometriosis symposium.The team share other science news relating to time travel, climate change, classical music and mathematics, and the science of experience.

2023 NSH co-presenters Gabriela De la Cruz and Lauren Ralph give great advice on selecting a topic and share why they decided to co-present at the 2023 NSH Convention. 

CardioNerds meet with fellows from The Christ Hospital, Drs. Hanad Bashir, Hyunsoo Chung, and Dalia Aziz to discuss the following case that highlights angioleiomyoma: A 60-year-old woman with a past medical history significant for breast cancer (on tamoxifen) presented as a transfer to our facility for a clot-in-transit. She had initially presented to the outside hospital after progressive dyspnea on exertion and recent syncope. She was found on an echocardiogram to have a right atrial mass spanning into the right ventricle. CTA of the chest and abdomen/pelvis demonstrated extensive thrombus burden spanning from the IVC into the right ventricle. She was transferred to our facility for intervention. Endovascular attempts were unsuccessful, at which point she underwent surgical thrombectomy. Gross examination of the mass revealed a cylindrical shape, homogeneous tan color, rubbery soft tissue, measuring 25.5 cm in length and 2.3 cm in diameter. Histology confirmed the presence of angioleiomyoma. A second, smaller mass (5.2cm long and 4mm in diameter) was removed from under the tricuspid valve, with histology consistent with leiomyoma. Estrogen receptor and progesterone receptor staining were strongly positive, leading to the discontinuation of tamoxifen. Given the presence of uterine fibroids identified on the CT scan, there was concern about a uterine origin. A hysterectomy is planned for her in the near future. Expert commentary is provided by Dr. Wojciech Mazur. Episode audio was edited by student Dr. Adriana Mares. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscript here. CardioNerds Case Reports PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Case Media - The Tall Tail Heart: Angioleiomyoma – The Christ Hospital Pearls - The Tall Tail Heart: Angioleiomyoma – The Christ Hospital Although evaluation of cardiac mass by echocardiography can provide information such as size, location, and morphology, adjunctive cross-sectional imaging may be used depending on the need for further temporal resolution (CT) or tissue characterization via cardiac MRI (CMR). If suspicious for elevated metabolic activity, there should be consideration of FDG-PET. Tamoxifen (a selective estrogen receptor modulator) is an agent used for breast cancer therapy. However, its use has been associated with endometrial hyperplasia, uterine fibroids, endometrial and uterine malignancy. Increased risk of malignancy has been seen more often in post-menopausal women and is dose and time-dependent. Clot in transient is a mobile thrombus, typically within the right heart structures. It is estimated to occur in 4-18% of patients with pulmonary embolism and is associated with elevated morbidity and mortality. Treatment includes surgical embolectomy, endovascular embolectomy, systemic thrombolysis, catheter-directed thrombolysis, or systemic anticoagulation. Angioleiomyoma is a rare benign pericystic tumor that most commonly affects the extremities. There are case reports of other affected sites, including the uterus. Invasion into the cardiac structures is exceedingly rare. The only established treatment for angioleiomyoma is surgical resection. Show Notes - The Tall Tail Heart: Angioleiomyoma – The Christ Hospital Syncope Syncope is a transient loss of consciousness secondary to reduced blood flow to the brain. Often, certain presentations are mislabeled as syncope, such as seizure disorders, posttraumatic loss of consciousness, and cataplexy. An organized diagnostic approach should be used to reduce hospital admissions and medical costs and increase diagnostic accuracy. Syncope can be divided into five general subgroups. 1) Neurally mediated reflex syncope (carotid sinus syndro...

This is Part 10 of our series looking at the Kokoda Campaign, looking at the combat performance of the 39th Battalion. The 39th Battalion was one of Australia's best Battalions.  Formed in Victoria, it's story is similar to that of the 53rd Battalion- but with some key differences.  We look at those differences with Dr David Cameron, an expert on the Battles of the Kokoda campaign. Have a listed Dr David Cameron, an expert on the Kookoda Campaign as he discusses the history and performance of the 39th Battalion.  Check out the show notes for the podcast for all of the information that we cover in this episode as well as the images and other details that didn't make it into the podcast.   Dr David Cameron's Biography David Cameron received first class Honours in Prehistory, University of Sydney and a PhD in Palaeoanthropology, Australian National University. He has written over twenty books covering Australian Military History, Colonial History, and Evolutionary Science with over 70 internationally peer reviewed papers published in various journals and book chapters. He is a former Australian Research Council Post Doctoral Fellow, School of Archaeology, Australian National University; and an Australian Research Council QEII Fellow in the Department of Anatomy and Histology, University of Sydney. He has conducted and led several international fieldwork projects in Europe (Hungary), Asia (Vietnam, India, and Japan), and the Middle East (Turkey, Jordan, Israel, and the United Arab Emirates) and conducted extensive museum studies and conferences (United States, Europe, and Asia). Before retiring in 2023, he was a senior analyst in the Australian Intelligence Community.   Books on the Papua Campaign by Dr Cameron:   Cameron, D.W. (in preparation – December 2024.) The Battle for Milne Bay, Big Sky Publishing Cameron, D.W. (in preparation – August 2024) Sanananda, Bastard of a Place: The Battle for the Beachhead, 1942-43, Big Sky Publishing Cameron, D.W. (in press – November 2023) Bloody Buna: The Battle for the Beachhead, 1942-43, Big Sky Publishing Cameron, D.W. (2023) Gona's Gone: The Battle for the Beachhead 1942, Big Sky Publishing Cameron, D.W. (2022) Retaking Kokoda: The Australian Advance Across the Owen Stanleys, Big Sky Publishing Cameron, D.W. (2022) Saving Port Moresby: Fighting at the End of the Kokoda Track, Big Sky Publishing Cameron, D.W. (2022) The Battle for Isurava: Fighting on the Kokoda Track in the heart of the Owen Stanleys, Big Sky Publishing Cameron, D.W.  (2020) The Battles for Kokoda Plateau: Three Weeks of Hell Defending the Gateway to the Owen Stanleys, Allen & Unwin Australia

Nutraceuticals for hair - Systemic ACD to drugs - Histology of AA vs androgenetic alopecia - Isotretinoin ocular AEs - Psych meds in psychodermatology - Want to donate to the cause? Do so here! http://www.uofuhealth.org/dermasphere Check out our video content on YouTube: https://www.youtube.com/@dermaspherepodcast and VuMedi!: https://www.vumedi.com/channel/dermasphere/ The University of Utah's Dermatology ECHO: ⁠⁠https://physicians.utah.edu/echo/dermatology-primarycare - ⁠⁠Connect with us! - Web: ⁠https://dermaspherepodcast.com/⁠ - Twitter: @DermaspherePC - Instagram: dermaspherepodcast - Facebook: https://www.facebook.com/DermaspherePodcast/ - Check out Luke and Michelle's other podcast, SkinCast! ⁠https://healthcare.utah.edu/dermatology/skincast/⁠ Luke and Michelle report no significant conflicts of interest… BUT check out our friends at: - ⁠Kikoxp.com ⁠(a social platform for doctors to share knowledge) - ⁠https://www.levelex.com/games/top-derm⁠ (A free dermatology game to learn more dermatology!)

This is Part 9 of our series looking at the Kokoda Campaign, looking at the combat performance of the 39th Battalion. This episode discusses the formation of the 39th Battalion, it's preparation for combat and how it performed on the Kokoda Trail.  The 39th Battalion is one of the Australian Army's most famous Battalion, a militia battalion that bore the brunt of the Japanese attacks down the Kokoda track.  What enabled it to fight so well? Have a listed Dr David Cameron, an expert on the Kookoda Campaign as he discusses the history and performance of the 39th Battalion.  Check out the show notes for the podcast for all of the information that we cover in this episode as well as the images and other details that didn't make it into the podcast. Dr David Cameron Biography David Cameron received first class Honours in Prehistory, University of Sydney and a PhD in Palaeoanthropology, Australian National University. He has written over twenty books covering Australian Military History, Colonial History, and Evolutionary Science with over 70 internationally peer reviewed papers published in various journals and book chapters. He is a former Australian Research Council Post Doctoral Fellow, School of Archaeology, Australian National University; and an Australian Research Council QEII Fellow in the Department of Anatomy and Histology, University of Sydney. He has conducted and led several international fieldwork projects in Europe (Hungary), Asia (Vietnam, India, and Japan), and the Middle East (Turkey, Jordan, Israel, and the United Arab Emirates) and conducted extensive museum studies and conferences (United States, Europe, and Asia). Before retiring in 2023, he was a senior analyst in the Australian Intelligence Community.   Books on the Papua Campaign by Dr Cameron:   Cameron, D.W. (in preparation – December 2024.) The Battle for Milne Bay, Big Sky Publishing Cameron, D.W. (in preparation – August 2024) Sanananda, Bastard of a Place: The Battle for the Beachhead, 1942-43, Big Sky Publishing Cameron, D.W. (in press – November 2023) Bloody Buna: The Battle for the Beachhead, 1942-43, Big Sky Publishing Cameron, D.W. (2023) Gona's Gone: The Battle for the Beachhead 1942, Big Sky Publishing Cameron, D.W. (2022) Retaking Kokoda: The Australian Advance Across the Owen Stanleys, Big Sky Publishing Cameron, D.W. (2022) Saving Port Moresby: Fighting at the End of the Kokoda Track, Big Sky Publishing Cameron, D.W. (2022) The Battle for Isurava: Fighting on the Kokoda Track in the heart of the Owen Stanleys, Big Sky Publishing Cameron, D.W.  (2020) The Battles for Kokoda Plateau: Three Weeks of Hell Defending the Gateway to the Owen Stanleys, Allen & Unwin Australia

In this episode, we review the high-yield topic of ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Liver Histology⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Gastrointestinal section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message

Join us for our AwardsCast series as we have short conversations with the 2023 NSH Award & Scholarship Recipients. In this episode, we talk to Program Director, Taiquanda Winbush, from Albany State University about how they will use the funds to improve their program with the funds from the scholarship.

Thank you for listening to this episode of "Health and Fitness" from the Nezpod Studios! Enjoy your night or the start of your day, spiced by our top-notch health and fitness/wellness updates coined from the best sources around the globe: made only for your utmost enjoyment and enlightenment… Click on subscribe to get more spicy episodes for free! See you again soon on the next episode of Health and Fitness Updates! Learn more about your ad choices. Visit megaphone.fm/adchoices

Thank you for listening to this episode of "Health and Fitness" from the Nezpod Studios! Enjoy your night or the start of your day, spiced by our top-notch health and fitness/wellness updates coined from the best sources around the globe: made only for your utmost enjoyment and enlightenment… Click on subscribe to get more spicy episodes for free! See you again soon on the next episode of Health and Fitness Updates! Learn more about your ad choices. Visit megaphone.fm/adchoices

Thank you for listening to this episode of "Health and Fitness" from the Nezpod Studios! Enjoy your night or the start of your day, spiced by our top-notch health and fitness/wellness updates coined from the best sources around the globe: made only for your utmost enjoyment and enlightenment… Click on subscribe to get more spicy episodes for free! See you again soon on the next episode of Health and Fitness Updates! Learn more about your ad choices. Visit megaphone.fm/adchoices

Join Drs Amelia Langston and Jonathan L. Kaufman, MD, as they discuss current CAR–T cell for B-cell lymphomas as leading researchers and practitioners in the field. Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/987069). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals. Resources Cancer Immunotherapy With Chimeric Antigen Receptor (CAR) T Cells https://emedicine.medscape.com/article/2500108-overview Multiple Myeloma https://emedicine.medscape.com/article/204369-overview CD19 https://www.ncbi.nlm.nih.gov/gene/930 BCMA in Multiple Myeloma - A Promising Key to Therapy https://pubmed.ncbi.nlm.nih.gov/34575199/ Histology, Plasma Cells https://www.ncbi.nlm.nih.gov/books/NBK556082/ Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma https://pubmed.ncbi.nlm.nih.gov/33626253/ Ciltacabtagene Autoleucel, a B-Cell Maturation Antigen-Directed Chimeric Antigen Receptor T-Cell Therapy in Patients With Relapsed or Refractory Multiple Myeloma (CARTITUDE-1): A Phase 1b/2 Open-Label Study https://pubmed.ncbi.nlm.nih.gov/34175021/ Progression-Free Survival: What Does It Mean for Psychological Well-Being or Quality of Life? [Internet] https://www.ncbi.nlm.nih.gov/books/NBK137763/ Ide-Cel or Standard Regimens in Relapsed and Refractory Multiple Myeloma https://pubmed.ncbi.nlm.nih.gov/36762851/ Clinical Management of Triple-Class Refractory Multiple Myeloma: A Review of Current Strategies and Emerging Therapies https://pubmed.ncbi.nlm.nih.gov/35877215/ Bispecific Targeting of CD20 and CD19 Increases Polyfunctionality of Chimeric Antigen Receptor T-Cell Products in B-Cell Malignancies https://pubmed.ncbi.nlm.nih.gov/35597752/ Bridging Chemotherapy: Multiple Myeloma https://www.ncbi.nlm.nih.gov/books/NBK584176/ Autologous Bone Marrow Transplant https://www.cancer.gov/publications/dictionaries/cancer-terms/def/autologous-bone-marrow-transplant Myelodysplastic Syndrome (MDS) https://emedicine.medscape.com/article/207347-overview GPRC5D-Targeted CAR T Cells for Myeloma https://pubmed.ncbi.nlm.nih.gov/36170501/ Talquetamab, a T-Cell–Redirecting GPRC5D Bispecific Antibody for Multiple Myeloma https://pubmed.ncbi.nlm.nih.gov/36507686/ Elotuzumab: The First Approved Monoclonal Antibody for Multiple Myeloma Treatment https://pubmed.ncbi.nlm.nih.gov/27493709/ Natural Killer Cells in the Malignant Niche of Multiple Myeloma https://pubmed.ncbi.nlm.nih.gov/35087536/

Cancer biopsies are scary. The patient gets tissue removed from his or her body, the sample gets sent off to the lab and then there's the agonizing wait for the results.  Dr. Stephen Boppart of the University of Illinois Urbana-Champaign, both a physician and an engineer, is working on instant biopsies that will produce results in minutes. Using laser light and artificial intelligence, Dr. Boppart and his colleagues have been able to identify cancers early and accurately. Moreover, this technique promises to identify conditions in the body that might lead to future cancers by looking at tiny vesicles, liquid-filled sacs that act as messengers.  His "Town Talk" sponsored by Telluride Science, was recorded at the Telluride Mountain Village Conference Center in Colorado.  The program was moderated by veteran broadcast journalists Judy Muller and George Lewis.

Season 4, Episode 3

NASH-TAG 2023 proved to be a watershed moment for Fatty Liver disease as exciting drug development readouts, powerful academic work on non-invasive tests and the willingness to dive into the toughest questions aligned in Deer Valley, Utah. In this weekend's conversation series, Surfing NASH reviews its diverse coverage of the conference by showcasing key excerpts across six recordings with various KOLs, patient advocates and stakeholders.This conversation with Naim Alkhouri, Amy Articolo and Jörn Schattenberg begins with Naim illustrating some of the high points of the meeting. First, he recaps the resmetirom data. He then highlights that Intercept's study of patient response to obeticholic acid (OCA) revealed improvements among the F3 population. He concludes that in the wake of these aforementioned results, there remains plenty of opportunity to improve and other biotechs “are still in the game” with the energy to back them. Jörn notes the high level of engagement from academia in supporting development through the consortia, NIMBLE and LITMUS. Amy credits the collaborative spirit of the meeting and the milestones achieved in improving the field's understanding of how best to utilize NITs to provide insight and serve patient needs. Roger Green steers conversation toward the challenges of payers and gaps in therapeutic efficacy for certain populations. He connects these ideas to slides presented by Naim on AI-driven zonal analysis developed by HistoIndex. The assessment provides a geographic vantage point that offers perspective on how to combine agent benefits and trial emerging opportunities. Amy agrees that some of the complex analytics will help pharma build its case for patients. Naim questions what we call “futility” – if patients stay the same, are they futile? He suggests that AI can help us determine whether people who do not reduce fibrosis are actually benefiting from therapy. Roger notes that Naim outlined three categories: patients whose fibrosis regressed, others who progressed and a third group somewhere in the middle yet to be defined. Naim agrees and underscores that with the non-invasive tests available, we can learn far more than what's known today. Amy responds with questions around how tests will be used practically, noting that stacked tests are pivotal to the story. As the conversation ends, Jörn notes biopsy is only one way to generate a conditional endpoint for drug approvals.

In an exclusive interview, Co-Founder and Chief Scientific Officer of HistoIndex, Dr. Dean Tai, joins Fatty Liver Researcher Prof. Dr. Jörn Schattenberg on Surfing the NASH Tsunami podcast with host, Roger Green. The trio discuss pertinent questions stemming from data derived from Phase 2 trial results of aldafermin and resmetirom whereby liver volume reduction was achieved in a considerably abbreviated period. HistoIndex was able to subsequently investigate fibrosis reduction in these studies by conducting AI-assisted histologic assessment to gather a deeper understanding of fibrosis dynamics on a continuous scale.Jörn introduces the corresponding poster held at NASH-TAG 2023, which reviews the application and compelling results of the qFibrosis® and qSteatosis® products. Dean then elucidates how AI-assisted zonal mapping of the liver delivers a targeted and statistically-improved assessment of fibrosis reduction. Interestingly, two distinctly different fibrosis regression patterns emerged between the aldafermin and resmetirom cohorts. The implication: highly-precise assessment of liver slides is sparking a spate of new questions surrounding therapeutic possibilities. Jörn offers two cogent observations. First, these technologies can drastically improve understanding of how much change in fibrosis really occurs. He points out that while many different MOAs are trialed in comparable populations, it may be that not all drugs are affecting fibrosis regression by the same mechanism. With the technology implemented by HistoIndex, researchers can now begin to assess the nuances of how and where these drugs act.A different, but critically important idea emerges: patients deserve to have the fullest extent of utility extrapolated from their donated tissue. There is also noted to be a plethora of existing data containing what Dean describes as “a gold mine” for retrospective analysis. The group continues on to explore and compare the myriad of potential future applications of these tools. It becomes clear that advancements in AI-based digital pathology are paving a path for an entirely new, imaginative line of thinking for the Fatty Liver field. Listen to the full feature for more on this illuminating topic.

Licenses/Credentials Doctor of Chiropractic, Board of Chiropractic Examiners, State of CA DC25312 1998 Work Experience 2017 – 2018 Dean of Clinics, Life Chiropractic College West 1998 Present Chiropractor/Proprietor, Providence Chiropractic Center 1995 – 1997 Teaching Assistant: Gross Anatomy, Spinal Anatomy, Histology; Research Assistant; Palmer College of Chiropractic West 1994 Vice President/Director, Palo Alto Institute of […] The post Having a Servant’s Heart in Chiropractic with Dr Jack Bourla DC – Chiro Hustle Podcast 410 appeared first on Chiro Hustle.

Licenses/Credentials Doctor of Chiropractic, Board of Chiropractic Examiners, State of CA DC25312 1998 Work Experience 2017 – 2018 Dean of Clinics, Life Chiropractic College West 1998 Present Chiropractor/Proprietor, Providence Chiropractic Center 1995 – 1997 Teaching Assistant: Gross Anatomy, Spinal Anatomy, Histology; Research Assistant; Palmer College of Chiropractic West 1994 Vice President/Director, Palo Alto Institute of […] The post Having a Servant’s Heart in Chiropractic with Dr Jack Bourla DC – Chiro Hustle Podcast 410 appeared first on Chiro Hustle.

Dr. Tatnai L. Burnett and Dr. Adela G. Cope of the Mayo Clinic in Rochester, MN discuss their recent publication "Association between laparoscopic appearance of superficial endometriosis, positive histology, and systemic hormone use".  Learn about their groundbreaking findings in the variability in endometriosis appearance and ideas about the direction for endometriosis surgery in the future. You won't want to miss this Podcast from these endometriosis surgery experts!

Dr. Meadow Campbell, PhD is an Assistant Professor at the Center for Anatomical Science and Education at Saint Louis University School of Medicine where she teaches anatomy and histology. Dr. Campbell {or, just Meadow} also shares her passion for these subjects on her social media accounts and her blog, called AnatomyLove. Dr. Campbell holds a master's degree in Biological Anthropology and a bachelor's degree in Anthropology and History from Wichita State University  More: On Instagram: _anatomylove_ On Twitter: @_anatomylove_ On TikTok: @anatomylove  

Episode 127 is one of our winter shorts, where I replay interesting segments from previous episodes. In this one, you'll hear about the role of platelets in immunity, how the Golgi apparatus gets its weird shape, exactly how hot mitochondria get, and why we may want to consider marking assignments and tests with a green pen, rather than a red one. 00:00 | Introduction 01:07 | Mitochondria 02:29 | Platelets 07:15 | Sponsored by AAA, HAPI, and HAPS 08:49 | Golgi Apparatus 13:51 | Green Pens 16:20 | Staying Connected   ★ If you cannot see or activate the audio player, go to: theAPprofessor.org/podcast-episode-127.html

Diagnosing diseases requires understanding of how cells respond to different medical conditions. Histology is a common two-dimensional way of studying such disease abnormalities, however major diseases are associated with three-dimensional cellular and tissue architectural changes. Dr Cheng's team has created X-ray histotomography, the first 3D imaging method that allows digital cell and tissue diagnostics from entire tissue samples and small organisms.Read more in Research OutreachRead the original article: https://doi.org/10.7554/eLife.44898

Video for this podcast: https://mehlmanmedical.com/audio-qbank-hy-usmle-q-586-pathology-histology Main website: https://mehlmanmedical.com/ Instagram: https://www.instagram.com/mehlman_medical/ Telegram private group: https://mehlmanmedical.com/subscribe/ Telegram public channel: https://t.me/mehlmanmedical Facebook: https://www.facebook.com/mehlmanmedical Podcast: https://anchor.fm/mehlmanmedical Patreon: https://www.patreon.com/mehlmanmedical

Enamel formation can be tough to understand. The process is somewhat complex and “cellular”. Don't sweat the small stuff as we take a closer look at all of the little things that go on in the process of enamel formation. This episode goes great with a review of tooth development and eruption as well. Check out this website for additional resources: https://blog.feedspot.com/dental_hygiene_podcasts/    Take a look at a product line I have tried and recommend #ad: https://bit.ly/thehappyflosser Promo code: HAPPYFLOSSER --- Send in a voice message: https://anchor.fm/billie43/message

Lung cancer is one of the most commonly diagnosed type of cancer and so it is fitting that we start the first of our disease-specific oncology series with this diagnosis. This week, we start our discussion on metastatic non-small cell lung cancer, focusing on NSCLC without driver mutations. * The approach to treatment of a patient with widespread metastatic NSCLC (mNSCLC) is very different than a patient without distant disease, which highlights why we do what we do:- Important to complete staging (discussed in prior episodes) to determine the extent of disease- Important to check molecular testing (looking for mutations in the cancer cells) and IHC for tumor proportion score (TPS) helps determine treatment options * Choosing a treatment is based on:- Histology - cannot use pemetrexed or bevacizumab in squamous cell - Platinum - Carboplatin is usually used (as opposed to our prior discussions about using Cisplatin because of LACE pooled analysis data)-- Why is Cisplatin not a great idea? Cisplatin should not be used if patients have (***high yield to know cisplatin eligibility criteria!!***): --- Poor performance status--- Patients with eGFR 50% can get IO monotherapy (spared chemotherapy)---- KEYNOTE 024: approval for pembrolizumab monotherapy in patient with PDL1>50%----- Study compared pembro to platinum doublet----- OS 70% vs. 50% at one year---- IMPOWER110: approval for atezolizumab monotherapy----- Study compared atezo to chemotherapy----- OS 64.9% vs 50% at 12 months--- Patients with score 50% WITHOUT SYMPTOMS: IO alone- In PDL1 >50% WITH SYMPTOMS: Chemo + IO- In PDL1

This case covers the pathophysiology, histology, and complications of Ulcerative Colitis vs. Crohn's Disease. The corresponding video and PDF notes are available on YouTube (https://youtu.be/nKaAVuvWiK8) and our website (https://www.dviacademy.com/offers/cVoy4VAN/checkout) Win a FREE 6 month membership to the DaVinci Academy video courses in Anatomy, Histology, and Biochemistry. Give DaVinci Cases a 5 star review and send a picture or screenshot to davincisupport@dviacademy.com - first 5 people to send their picture will receive the free 6 month membership. Mark Cuban Interview on The DaVinci Hour Podcast Video: https://youtu.be/BpgycKtjZJg Audio: https://www.dviacademy.com/the-davinci-hour-episode-26   20% off discount code (DC20) for video courses for anatomy, histology, and biochemistry available at https://www.dviacademy.com/ Other Podcast: The DaVinci Hour Podcast interviews attendings and residents across a variety of fields in medicine giving listeners insight into their experiences, career path, and advice for navigating one's career in medicine. Available at the links below: Podcast Website: https://www.dviacademy.com/the-davinci-hour Spotify: https://open.spotify.com/show/0llGfOXN5VBawQH9DteeQn?si=kyq4twtzTQaX-Ls0fHPk4A Apple Podcasts: https://podcasts.apple.com/us/podcast/the-davinci-hour/id1554398921 YouTube Channel: https://www.youtube.com/c/DaVinciAcademyMed/

In this episode Maxwell Cooper, M.D. interviews John Whyte, M.D., Chief Medical Officer of WebMD. Dr. Whyte gives an overview of his unique background starting with training in internal medicine and then working in roles at Medicare, the Food and Drug Administration (FDA), and as Chief Medical Expert at The Discovery Channel. Dr. Whyte continues to see patients as an internist and tells the listeners how that has benefited his other roles including his current work at WebMD. Dr. Whyte discusses how mobile apps, the internet, and multimedia have empowered patients to take control of their own health. In addition, he describes many of the latest resources that WebMD provides for patients in a variety of formats, including apps, video, audio, and print publications. Lastly, Dr. Whyte provides advice for physicians and other healthcare workers looking to become more involved in medical media. *Views expressed in this podcast are those of the individuals, not their respective institutions John Whyte, M.D. LinkedIn: https://www.linkedin.com/in/john-whyte-00092833/ Twitter: https://twitter.com/drjohnwhyte Instagram: https://www.instagram.com/drjohnwhyte/   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/ 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com Instagram: https://www.instagram.com/davinci_academy1/ Twitter: https://twitter.com/DviAcademy Facebook: https://www.facebook.com/dviacademy  

In this episode Maxwell Cooper, M.D. talks with Medical Ethicist and Emory University Professor John Banja, Ph.D. about the ethics of AI and medical errors, specifically what will happen when AI can outperform radiologists? Professor Banja has spent much of his career looking at the ethics involved in medical errors and recently has turned his focus to AI and radiology. He hosts the AI, Radiology and Ethics Podcast where he interviews leading radiologists and AI experts on ethical issues we will face with AI in the near future. The discussion during this episode looks at a number of medical error scenarios involving a future AI model that could perform at the same level as a radiologist. Specifically, Dr. Cooper and Professor Banja examine who would be liable in these scenarios, how these errors could be mitigated, and how these errors could be prevented. *Views expressed in this podcast are those of the individuals, not their respective institutions John Banja, Ph.D. https://ethics.emory.edu/who-we-are/our-people/faculty/core/banja-john.html https://twitter.com/john_banja   AI, Radiology and Ethics Podcast: https://anchor.fm/airadiologyethics   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/ 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com Instagram: https://www.instagram.com/davinci_academy1/ Twitter: https://twitter.com/DviAcademy Facebook: https://www.facebook.com/dviacademy

In this DaVinci Innovators+ episode Maxwell Cooper, M.D. interviews Gary Michelson, M.D. about his career as a physician-inventor and the invention process. Dr. Michelson practiced spine surgery for over 25 years while at the same time inventing numerous spine surgery devices, resulting in over 900 patents worldwide. In 2005 he sold his portfolio of patents to Medtronic for $1.4 billion. He went on to start a number of philanthropic organizations grouped under Michelson Philanthropies that focus on medical research, education, animal rights, and intellectual property. Dr. Michelson tells the listeners about his invention process, how he balanced being a full-time practicing surgeon and a prolific inventor, and how he commercialized his inventions. Dr. Michelson provides advice for aspiring inventors and how physicians can utilize their clinical experience to identify clinical needs and develop innovative solutions. Lastly, Dr. Michelson discusses his current philanthropic work, including how his foundations are funding young scientific investigators and a new center for immunology research in California. +DaVinci Innovators is a series of episodes of The DaVinci Hour Podcast that feature physicians, inventors, and entrepreneurs working on innovative medical technology. Guests discuss developing new medical technology, building medtech companies, and advice for anyone going through the process of medical innovation. *Views expressed in this podcast are those of the individuals, not their respective institutions Michelson Philanthropies Website: https://www.michelsonphilanthropies.org/ Twitter: https://twitter.com/MichelsonPhils Instagram: https://www.instagram.com/michelsonphilanthropies/ Michelson Medical Research Foundation Website: https://www.michelsonmedicalresearch.org/ Twitter: https://twitter.com/MichelsonMedRF Instagram: https://www.instagram.com/garymichelsonmmrf/   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/ 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com Instagram: https://www.instagram.com/davinci_academy1/ Twitter: https://twitter.com/DviAcademy Facebook: https://www.facebook.com/dviacademy

In today's clip, Dr. Paul is talking about his EXTREMELY TOUGH histology teacher in his 1st semester of medical school and what it took to pass the class... As well as go over some of the ways to build a rock-solid histology study strategy that will get you outstanding results in medical school and on your USMLE Step 1 exam.If you found this clip to be helpful, check out the FULL episode on our YouTube channel at https://youtu.be/dUygdVGdhPgDon't forget to follow us on IG for even more daily USMLE & med school tips & strategies:Dr. Paul: instagram.com/realdrpaulDr. Stavros: instagram.com/realdrstavrosThe USMLE Guys account: instagram.com/theusmleguysThanks for tuning in to the show!

In this series, PathPod gathers pathologists Around The Scope to discuss their work in depth. Today, we learn about renal pathology. Our host, Dr. Sara Jiang (@Sara_Jiang) speaks with Dr. Mei Lin Bissonnette (@BCRenalPath), Director of the British Columbia Provincial Renal Pathology Laboratory, Dr. Carla Ellis (@theglasspusher), Director of Renal Pathology in the Department of Pathology at Northwestern University, Dr. Alcino Gama (@AlcinoGama), PGY2 at Northwestern Pathology, and Dr. Vighnesh Walavalkar (@vighnesh_w), Director of Histology at the University of California San Francisco.  What is new and exciting in the field of renal pathology? How is the Renal Pathology Society supporting DEI efforts? What is two-handed fly fishing? Learn about these questions as well as about our expert guests!   Renal pathology society: https://www.renalpathsoc.org/ https://www.renalpathsoc.org/Diversity-Equity-and-Inclusion https://www.facebook.com/renalpathologysociety Twitter: @Renalpathsoc   Public domain music: Main Stem by US Army Blues

In this DaVinci Innovators+ episode Maxwell Cooper, M.D. interviews Navin Goyal, M.D., Co-Founder and CEO of LOUD Capital. Dr. Goyal discusses his career path that began as an anesthesiologist working in a private practice that became involved with angel investing and advising start-ups, and eventually co-founding multiple companies. He discusses why he left clinical practice to pursue entrepreneurship and investing full time. Dr. Goyal gives an overview of how LOUD Capital aims to invest in early stage companies in a variety of industries that are making a significant impact. Dr. Goyal recently wrote a book titled Physician Underdog that describes his journey from medicine to venture capital and gives insights on how physicians can feel empowered to pursue non-clinical opportunities that are meaningful and impactful.  +DaVinci Innovators is a series of episodes of The DaVinci Hour Podcast that feature physicians, inventors, and entrepreneurs working on innovative medical technology. Guests discuss developing new medical technology, building medtech companies, and advice for anyone going through the process of medical innovation. *Views expressed in this podcast are those of the individuals, not their respective institutions Navin Goyal, M.D. LinkedIn: https://www.linkedin.com/in/navingoyalmd/ Instagram: https://www.instagram.com/navin.g.md/ LOUD Capital: https://loud.vc/ Physician Underdog Website: https://www.physicianunderdog.com/ Physician Underdog on Amazon: https://www.amazon.com/Physician-Underdog-Leveraging-underdog-mentality-ebook/dp/B09NLKL1GX Beyond Physician: https://beyondphysician.com/   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/ 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ Twitter: https://twitter.com/DviAcademy Instagram: https://www.instagram.com/davinci_academy1/ Facebook: https://www.facebook.com/dviacademy LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com  

Lung Cancer Histology and Staging*Workup for a nodule that is concerning: **Ensure there is a dedicated CT scan of the chest to evaluate **Try to obtain old imaging; the rate of change is important **Can get PET, but even if a lesion if not FDG-avid, but growing quickly we should consider biopsy anyway**Referral to pulmonary medicine, who can assist with biopsy and also regional lymph node evaluation (important – more below)**PFTs are often ordered because it provides information about lung function in anticipation of possible surgery for treatment Lung Cancer Histology: *Non-small cell lung cancer (NSCLC)**Umbrella term for a variety of cancers**Increased risk in smokers**More common types: ***Adenocarcinoma (~50% of all lung cancers)****Most common overall; cancer of the mucus producing cells****IHC: TTF-1, NapsinA, CK7 positive***Squamous Cell Carcinoma (22.7%)****More often seen in patients with a smoking history ****IHC: p63 positive and cytokeratin pearls***Remaining ~15% are the other types of lung cancer / mixed histologies**Small cell lung cancer (SCLC)***Neuroendocrine tumor with very different pathology***Much more aggressive than NSCLC***Oncologic emergency***IHC: Chromogranin and synaptophysin positive IHC pearls: TTF-1 usually means lung cancer (but can be negative in squamous cell lung cancer). This will be important in the future (we promise :])*Staging for NSCLC:**Nodal evaluation: lymph node evaluation is part of the workup for NSCLC**Single digit = central/mediastinal nodes (higher risk)**Double digit = peripheral/hilar/intrapulmonary lymph nodes (lower risk)**“R” vs. “L” is direction *Pearl: Why is this important? If there is nodal involvement, systemic therapy is going to be necessary *Putting it all together: **T: Tumor size: T1-4**N: Nodal involvement***N0: no nodal involvement ***N1: Nodes closest to the primary tumor (double digits)****Ipsilateral peribronchial, hilar, intrapulmonary ***N2: Further away (single digit)****Ipsilateral mediastinal and/or subcarinal LN***N3: Contralateral any node or supraclavicular LN **M: Metastasis – in lung cancer, patients with certain patterns of metastatic disease are still curable! ***M0: no mets***M1a: Contralateral lobe, pleural effusion or pericardial effusion à these are generally still curable!***M1b: single site of metastatic disease à these are generally still curable!***M1c: multiple sites of metastatic disease à these are generally not curable*Staging for SCLC: **Limited stage - meaning it can fit in “one radiation field”**Extensive stage - does not fit in “one radiation field”*Once lung cancer is diagnosed:**Go to NCCN to learn the flow of ongoing management**Complete staging (if not already done):***CT C/A/P (don't necessarily need if a PET scan is done)***PET Scan***MRI brain à in general this is needed, but there are some exception to this (see NCCN)**Referral to pulmonary for nodal evaluationReferences: NCCN.orghttps://doi-org.proxy.library.vanderbilt.edu/10.1016/j.semcancer.2017.11.019-Article about IHC markers for lung cancer Please visit our website (TheFellowOnCall.com) for more information Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast

In this episode Dr. Maxwell Cooper interviews Dr. Lars Svensson, a cardiothoracic surgeon and the Heart & Vascular Institute Chair at Cleveland Clinic. Dr. Svensson is an expert in aortic surgery and minimally invasive techniques, including percutaneous transcatheter aortic valve replacement (TAVR). He was a PI for the groundbreaking PARTNER clinical trials that established TAVR as a safe and effective treatment option for patients with aortic valve disease. Dr. Svensson tells the listeners about his days as surgical resident learning under giants in cardiothoracic surgery, including Dr. Christian Barnard - the first surgeon to perform a human heart transplant, and the world renowned Dr. Michael DeBakey. He gives an overview of his clinical practice as a cardiothoracic surgeon and his responsibilities as the Heart and Vascular Institute Chair at Cleveland Clinic. Additionally, he discusses how Cleveland Clinic has been able to remain the #1 ranked heart hospital in the world for the last 28 consecutive years and the future of cardiovascular healthcare. Dr. Svensson describes his innovative process that has lead to many new techniques and devices for aortic surgery and percutaneous valve replacement. Lastly, Dr. Svensson provides advice for residents and medical students on how they can make innovative contributions to medicine. *Views expressed in this podcast are those of the individuals, not their respective institutions   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/ 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ Twitter: https://twitter.com/DviAcademy Instagram: https://www.instagram.com/davinci_academy1/ Facebook: https://www.facebook.com/dviacademy LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com

In this episode Dr. Maxwell Cooper interviews Dr. Yang Yang, an integrated vascular surgery resident at MedStar Health/Georgetown University School of Medicine. Dr. Yang gives an overview of the field of vascular surgery and why she chose the specialty. Dr. Yang also describes a typical day, lifestyle, and call for a vascular surgery resident. She talks about her gap years before medical school and her vascular surgery research year between M3 and M4. Dr. Yang tells us about how she has built a large Instagram following featuring her life as a vascular surgery resident. Lastly, Dr. Yang provides advice for medical students for performing well on away rotations and putting together the best possible residency application. *Views expressed in this podcast are those of the individuals, not their respective institutions Yang Yang, M.D. Instagram: https://www.instagram.com/yangyang_md/ YouTube: https://www.youtube.com/c/YangYangMD Twitter: https://twitter.com/YangYang_MD   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/ 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ Twitter: https://twitter.com/DviAcademy Instagram: https://www.instagram.com/davinci_academy1/ Facebook: https://www.facebook.com/dviacademy LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com

In this episode Dr. Maxwell Cooper interviews Richard J. Brown, M.D., a plastic surgeon in private practice in Scottsdale, AZ. Dr. Brown gives an overview of the field of plastic surgery and the focus of his current practice. He tells the story of how he started his private practice out of training and built up a reputation and referral base in his community. Dr. Brown also discusses how he has built a massive following on social media (675k on YouTube, 100k on IG, 7M on TikTok) through aiming to inspire and educate people about plastic surgery, medicine, health, wellness, and pursuing their dreams.  He discusses the business side of private practice and some of his newest business ventures in addition to his practice. Lastly, Dr. Brown gives advice to medical students and residents considering the field of plastic surgery and how they can make themselves competitive applicants. *Views expressed in this podcast are those of the individuals, not their respective institutions Richard J. Brown, M.D. Website: https://www.richardjbrownmd.com/ YouTube: https://www.youtube.com/c/BrownPlasticSurgery/ Instagram: https://www.instagram.com/drrichardjbrown/ TikTok: https://www.tiktok.com/@therealtiktokdoc Facebook: https://www.facebook.com/DrRichardJBrown/   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/ 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ Twitter: https://twitter.com/DviAcademy Instagram: https://www.instagram.com/davinci_academy1/ Facebook: https://www.facebook.com/dviacademy LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com

In this DaVinci Innovators+ episode Dr. Maxwell Cooper interviews Pelu Tran and Kenneth Ko, Co-Founders of Ferrum Health. Pelu and Ken give an overview of how Ferrum Health provides AI Hubs for healthcare systems that consist of validated AI algorithms that improve workflow efficiency, diagnostic ability, and outcomes for a variety of clinical areas, including oncology, orthopaedics, and cardiology. The AI algorithms that are part of Ferrum's Hubs have been shown to triage radiology worklists to prioritize studies with potentially critical findings, aid radiologists with making diagnoses, and decrease error rates. The discussion also covers how AI can be can help decrease the ever growing demands on radiologists, identify potential areas of workflow improvement, and be applied to rural health systems to improve access to care. +DaVinci Innovators is a series of episodes of The DaVinci Hour Podcast that feature physicians, inventors, and entrepreneurs working on innovative medical technology. Guests discuss developing new medical technology, building medtech companies, and advice for anyone going through the process of medical innovation. *Views expressed in this podcast are those of the individuals, not their respective institutions Ferrum Health Website: https://ferrumhealth.com/ Twitter: @ferrumhealth LinkedIn: https://www.linkedin.com/company/ferrumhealth/   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/ 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ Twitter: https://twitter.com/DviAcademy Instagram: https://www.instagram.com/davinci_academy1/ Facebook: https://www.facebook.com/dviacademy LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com

In this DaVinci Innovators+ episode Dr. Maxwell Cooper interviews Mark Cuban, a serial entrepreneur, Owner of the Dallas Mavericks NBA Team, a Shark on ABC's Shark Tank Series, and Co-Founder of Mark Cuban Cost Plus Drugs. Mark outlines how Cost Plus Drugs is obtaining medications directly from manufacturers and wholesalers to provide medications at the lowest prices possible in the most transparent way. He also describes how physicians can easily send prescriptions to CostPlusDrugs.com and how patients can sign up. Mark tells the story of how his Co-Founder, Dr. Alex Oshmyansky cold emailed him about starting Cost Plus Drugs.  Lastly, Mark describes his experience working with physician-entrepreneurs and gives advice for physicians starting companies. +DaVinci Innovators is a series of episodes of The DaVinci Hour Podcast that feature physicians, inventors, and entrepreneurs working on innovative medical technology and building companies impacting healthcare.  *Views expressed in this podcast are those of the individuals, not their respective institutions Mark Cuban Cost Plus Drug Company Website: https://costplusdrugs.com/ Twitter: @costplusdrugs Instagram: @costplusdrugs   The DaVinci Hour Podcast Website: https://www.dviacademy.com/the-davinci-hour DaVinci Academy Website: https://www.dviacademy.com/   20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/store YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ Twitter: https://twitter.com/DviAcademy Instagram: https://www.instagram.com/davinci_academy1/ Facebook: https://www.facebook.com/dviacademy LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com

On this episode, Cody & Ethan chat with Heather Stevens, owner of Wildlife Analytical Laboratories. You will hear the following: -Find out what Histology is -Heathers Background -How she Acquired Wildlife Analytical Laboratories or also known as Deer Age & of course, the other rabbit holes that we go down! This episode is full of information, and you won't want to miss it! Partners and discounts Forget Genetics LLC use code: BACKCTRYPA 20% and save 20% Deer Age - Orders Use code: BACKCOUNTRYPA 10% your first order Habit Outdoors - Our gear, your adventure.

In this episode we interview Todd Hanna, M.D., D.D.S., an Oral & Maxillofacial Surgery in private practice in New York City. He has a special clinical focus in face and jaw aesthetic surgery and head and neck microvascular reconstruction. Dr. Hanna tells us the story of his training pathway toward his current practice, which involved going to medical school and dental school along with completing two fellowships in Maxillofacial Microvascular Reconstruction at Shock Trauma Hospital and Head & Neck Surgical Oncology Lenox Hill Hospital. Dr. Hanna outlines how he started and maintains his busy independent private practice, including building a popular and educational Instagram page featuring many of his cases. He also provides advice for starting a private practice and building a network of colleagues and referrals. Lastly, Dr. Hanna describes the art behind planning his complex surgeries to achieve the best outcomes for his patients. *Views expressed in this podcast are those of the individuals, not their respective institutions 20% off Discount Code (TDH20) for DaVinci Academy's online video courses for Anatomy, Histology, and Biochemistry available at https://www.dviacademy.com/ Podcast Website: https://www.dviacademy.com/the-davinci-hour eBooks for anatomy and biochemistry available on: Google Play: https://play.google.com/store/books/author?id=Maxwell+Cooper+M.D Amazon: https://www.amazon.com/M.D.-Maxwell-Cooper/e/B086XHSK3R YouTube: https://www.youtube.com/c/DaVinciAcademyMed/ Twitter: https://twitter.com/DviAcademy Instagram: https://www.instagram.com/davinci_academy1/ Facebook: https://www.facebook.com/dviacademy LinkedIn: https://www.linkedin.com/company/davinci-academy---dviacademy.com