Podcasts about Dysbiosis

In this episode, I'll cover the root causes of reflux & share the most effective treatments. Tune in! Work with us! https://drruscio.com/virtual-clinic/ Product mentions:  Thiamega https://www.objectivenutrients.com/products/thiamega/ Vagustim https://vagustim.io/   Watch next

Rewiring Your Vagus Nerve: A Functional ApproachWhile vagus nerve exercises like cold plunges and humming are popular, this episode explores a deeper functional perspective. What if underlying factors like mineral imbalances, gut issues, mold exposure, or structural misalignments are blocking your vagal function?The Mineral ConnectionYour vagus nerve functions as your body's electrical system, with minerals as crucial conductors. Hair Tissue Mineral Analysis reveals important patterns:- Calcium/Magnesium Ratio: Excessive calcium dominance keeps you stuck in "fight or flight"- Calcium/Phosphorus Ratio: Ideally balanced at 2.3:1 for optimal function- Potassium Levels: Low levels signal insufficient nerve energy- Heavy Metal Burden: Toxic metals hijack nerve function by stealing mineral binding sites"Your vagus nerve is your digestive system's power cord. Mineral imbalances create short circuits!"The Gut-Vagus ConnectionYour gut contains the second largest neural system after the brain. Comprehensive stool testing can identify issues affecting vagal function:- Low microbial diversity correlates with reduced vagal tone- Deficiencies in butyrate-producers deprive the nerve of energy- Dysbiosis creates inflammation that dampens signalingThis creates a feedback loop: poor vagal tone worsens digestive function, increasing dysbiosis, further impairing vagal tone.Mold ExposureMold illness disrupts vagus nerve function through:- Direct neurotoxicity to vagal nuclei- Mitochondrial damage impairing energy production- Inflammatory cascades that dampen vagal toneMany experience treatment resistance because underlying mycotoxin burden continues suppressing function.Structural ConsiderationsThe vagus nerve can physically get "pinched" due to:- Cranial misalignments- Neck tension- Rib cage restrictions- Abdominal compressionThis explains why bodywork sometimes dramatically improves digestion when supplements haven't helped.Practical Support StrategiesWhile addressing root causes, try:1. Singing: Creates vibrations that stimulate the vagus2. Essential Oils: Applied diluted behind the ears3. Digestive Bitters: Trigger vagal firing4. Omega-3 Fatty Acids: Provide building blocks for nerve structureThe Holistic ApproachRather than isolated "hacks," assess your unique terrain. When we restore harmony to the entire ecosystem, vagal tone naturally improves, with benefits cascading throughout your physiology.Looking for deeper support? Visit the "Work With Me" page on my website to learn about my approach to mineral balancing and microbiome optimization – two key pillars that profoundly affect vagus nerve function and overall health. Mineral Foundations Course HERE Learn more about how you can I can work together HERE Book an initial health session HERE Join my newsletter HERE If you are interested in becoming a client and have questions, reach out by emailing me: connect@lydiajoy.me Find me on Instagram : @ Lydiajoy.me OR @ holisticmineralbalancing

In today's episode, we detail the enteric nervous system and regulation of gastrointestinal motility. We discuss factors including dysautonomia, stress, microbial overgrowth, and more, with regards to potential effects upon gastrointestinal motility. We further detail symptoms of altered GI motility. Topics:1. Introduction to Gastrointestinal Motility- Orchestrated contraction of smooth muscles that propel contents along the digestive tract.  - Roles in mixing, absorption, and preventing bacterial overgrowth.- Disruptions in motility. 2. The Enteric Nervous System (ENS) and Its Role- Myenteric and submucosal plexus.- Coordinating contractions and relaxations for effective motility. - Mucosa includes epithelium, lamina propria, and muscle.  - Submucosa houses the submucosal plexus.  - Muscularis externa. - Inner circular and outer longitudinal muscle layers with the myenteric plexus in between.   3. The Role of Interstitial Cells of Cajal (ICCs)- Specialized pacemaker cells in muscular layers  - Generate slow-wave electrical activity to synchronize smooth muscle contractions  - Critical for peristalsis.- Work with neural inputs to fine-tune gut motility   4. Dysautonomia and Its Impact on Gut Motility- Dysfunction of the autonomic nervous system (ANS)  - Motility impacts- Microbial overgrowth, SIBO 5. Gastrointestinal Dysmotility- Neurological dysregulation - Structural abnormalities and smooth muscle dysfunction  - Hormonal imbalances - Microbial overgrowth - Autoimmunity  6. The HPA Axis- Hypothalamus, pituitary gland, adrenal glands  - Central to the stress response and interlinked with gut function  - The amygdala and PVN of the hypothalamus  - CRH stimulates ACTH, leading to cortisol release from adrenal glands   7. Cortisol and Gut Barrier Function- Cortisol is a glucocorticoid that modulates immune function and gut physiology  - Chronic cortisol exposure can impair tight junction (TJ) integrity  - Increases paracellular permeability and allows passage of antigens and endotoxins   8.Stress-Induced Changes in Gut Motility- Slow gastric motility - Increased colonic motility  9. Symptoms of GI Dysmotility10. Addressing Root Cause(s)Thank you to our episode sponsor:1. Shop ⁠⁠⁠⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠⁠⁠⁠⁠⁠⁠Peach Cider Vinegar⁠⁠⁠⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Story at-a-glance Type 2 diabetes affects 10.5% of adults globally, projected to rise to 12.2% by 2045, with 90% of cases being Type 2 diabetes A study revealed that gut microbiome responses to high- and low-carbohydrate diets influence blood sugar and metabolic health Dysbiosis in the gut microbiome is linked to Type 2 diabetes, affecting carbohydrate metabolism, fat storage, inflammation and glycemic control Short-chain fatty acids (SCFAs) from gut bacteria reduce inflammation and enhance insulin sensitivity, playing a key role in preventing diabetes and metabolic imbalances Optimizing gut health through mitochondrial support, healthy carbohydrates and targeted supplementation like Akkermansia muciniphila improves glycemic control and overall metabolic function

Matters Microbial #85: The Microbiomes of Hawai'ian Seascapes April 3, 2025 Today, Dr. Rosie 'Anolani Alegado of the University of Hawai'i at Mānoa  joins the #QualityQuorum to discuss how weather, climate, and human intervention impact the microbiota to be found in human related seascapes around Hawai'i. Host: Mark O. Martin Guest: Rosie 'Anolani Alegado Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode An overview of how Hawai'i was settled from Polynesia. An essay describing indigenous Hawai'ian culture and its collaborative relationship to the land and sea. A must read book “Coral Reefs in a Microbial Sea,” by the late Merry Youle, Forest Rohwer, and Derek Vosten. Here are several links related to the work of Dr. Isabella Abbott, including this one from Pacific Science.  Again, well worth your reading. An overview of the field of ethnobotany, championed by Dr. Abbott. Dr. Alegado's previous research was with the fascinating choanoflagellates, which can tell us about the evolution of complex life.  Here is a video about these ancient relatives of us all.  Here is a article from Dr. Alegado describing a bacterial role in the development of this fascinating organism. An overview of the “One Health” concept linking human interactions, animals, plants, the land, and the ocean. A focus of Dr. Alegado's group research involving the indigenous Hawai'ian  fishponds. An overview of community restoration of these ancient structures. The role of taro in ethnobotany. A fine description of indigenous Hawai'ian mariculture. The concept of dysbiosis. Tropical storm Wali, which impacted the Hawai'ian Islands. An overview of alpha diversity and beta diversity in microbiome studies. A fine book about Dr. Barbara McClintock, “A Feeling for the Organism.” Here is a wonderful video in which Dr. Alegado describes the work of her research group and her interests in the fishponds of Hawai'i. Dr. Alegado's faculty website. Dr. Alegado's very interesting research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Chronic stress disrupts the gut microbiome by altering the HPA axis and increasing inflammation, leading to dysbiosis and reduced beneficial bacteria like Lactobacillus and Bifidobacterium. In this episode, we discuss how to mitigate these effects and restore gut health through a multifaceted approach. Key Strategies: Regulate Stress & Lower Cortisol: Practices like mindful breathing and HRV training Adaptogens (Ashwagandha, Rhodiola) Morning sun exposure to stabilize cortisol Support Gut Integrity & Reduce Inflammation: L-Glutamine and colostrum for gut repair Bone broth and butyrate to heal the gut lining Rebuild Beneficial Bacteria: Probiotics: Lactobacillus rhamnosus GG and Bifidobacterium longum Prebiotics: Resistant starch, polyphenols, and fermented foods Support Vagus Nerve Function: Cold exposure and low-intensity exercise to balance the nervous system Improve Sleep: Supplements like Magnesium Glycinate and L-Theanine to support relaxation and reduce cortisol spikes By following these strategies, you can restore microbial balance, reduce inflammation, and enhance resilience to stress. Why Work with a FDN Practitioner? When addressing stress-induced dysbiosis, it's crucial to test, not guess. Working with a Functional Diagnostic Nutrition Practitioner (FDNP) allows you to personalize your protocol through functional lab testing. This approach eliminates the cycle of trial and error, providing precise insights into your unique health needs. A personalized, evidence-based plan can help you achieve optimal results and sustainable health outcomes.

For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we've been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging? In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in microbiome innovation, to expose why most probiotics fail—and how one company's scientifically validated approach could redefine your gut, brain, immune system, and even your metabolism. You'll learn how dysbiosis may be wrecking your brain without you knowing it, why your probiotic likely died in your stomach acid, and the secret to rebooting your microbiome after antibiotics, GLP-1 drugs, or years of toxic exposure. This isn't just about digestion—your gut controls your cravings, energy, sleep, mood, and aging trajectory. So what's the one upgrade that can actually reset your gut… for good? What You'll Learn in This Episode: • Why your gut—not your brain—is making most of your decisions • How 93% of probiotics on the market fail before they reach your intestines • The “AB 10” protocol that rebuilds your gut after antibiotics or SIBO • What GLP-1 weight-loss drugs are doing to your microbiome (and how to stop it) • The shocking gut–brain–heart axis connection you've never heard of • Why inflammation, brain fog, and mood swings may start with leaky gut • Which probiotic strains are clinically proven to improve cognition and mood • What to do if you want to eat gluten again—or survive American wheat • How a fermented papaya concentrate could replace your acid reflux meds • Why optimizing your gut could extend your lifespan by 40% ***Get 20% off your next purchase by going to https://omnibioticlife.com/pages/dave-asprey/ or omnibioticlife.com/dave*** SPONSORS -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ • OMNi-BiOTiC's Instagram – https://www.instagram.com/fatty15/ • OMNi-BiOTiC's Website: https://omnibioticlife.com/ • 2025 Biohacking Conference: https://biohackingconference.com/2025 • Danger Coffee: https://dangercoffee.com • Dave Asprey's Website: https://daveasprey.com • Dave Asprey's Linktree: https://linktr.ee/daveasprey • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com Timestamps: • 00:00 – Trailer • 03:15 – Intro • 05:05 – Probiotics, Prebiotics, and Postbiotics Explained • 08:21 – The Importance of Delivery Mechanisms • 17:36 – Addressing SIBO and Gut Health Protocols • 31:55 – The Impact of GLP-1 Drugs on Gut Health • 39:26 – The Role of Gut Bacteria in Hunger and Fasting • 40:01 – Painkillers and Gut Health: A Personal Experience • 40:51 – The Dangers of Proton Pump Inhibitors • 42:00 – The Importance of Stomach Acid • 44:55 – Probiotics for Chronic Conditions • 48:38 – The Impact of Glyphosate on Gut Health • 57:04 – Alcohol and Gut Bacteria • 01:02:01 – New Solutions for Acid Reflux • 01:07:57 – The Future of Gut Health and Longevity • 01:11:33 – Conclusion and Special Offer See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Continuing our 'Got Gut Health?' Series, today's episode will dive into the topic of gut dysbiosis, the gut microbiome, and issues that arise from gut dysbiosis. ---------- ⁠⁠Join Our Gut Health 101: Demystifying Digestive Health on April 15th, 2025⁠----------Topics include:- Part 3 of Got Gut Health Series- Gut Health 101 Workshop- Gut Dysbiosis- Gut Microbiome Starts at Birth- What is Bacterial Dysbiosis?- Potential Side Effects- IBS- Autoimmune Diseases- CRONS- Tom Brady's Stool- Causes of Dysbiosis---------- ⁠⁠⁠⁠⁠⁠⁠My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.metabolismschool.com⁠⁠⁠⁠⁠⁠⁠---------- [Free] Metabolism School 101: The Video Series⁠⁠⁠⁠⁠⁠⁠http://www.metabolismschool.com/metabolism-101⁠⁠⁠⁠⁠⁠⁠----------Subscribe to My Youtube Channel: ⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1⁠⁠⁠⁠⁠⁠⁠----------⁠⁠⁠⁠⁠⁠⁠Grab a Copy of My New Book - Metabolism Made Simple⁠⁠⁠⁠⁠⁠⁠---------- Stay Connected: ⁠⁠⁠⁠⁠⁠⁠Instagram: @sammillerscience⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠Youtube: SamMillerScience⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠Facebook: The Nutrition Coaching Collaborative Community⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠TikTok: @sammillerscience⁠⁠⁠⁠⁠⁠⁠  ----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at ⁠⁠⁠⁠⁠⁠⁠operations⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@sammillerscience.com⁠⁠⁠⁠⁠⁠⁠. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."

Chronic Food Allergies and Sensitivities: What's Really Causing Them | Podcast #449

In this episode, we detail the cellular make-up of the gastric lining, highlighting hydrochloric acid (HCl) secretion and its role in digestion, micronutrient absorption, and microbial defense. We discuss potential pathophysiological consequences of hypochlorhydria, including impaired digestive signaling, bacterial overgrowth in the small intestine (SIBO), and more. Lastly, we detail upstream microbial control, focusing on the influence of the oral microbiome and oral dysbiosis.Topics: 1. Introduction- Highlighting the stomach and hypochlorhydria / low stomach acid, as well as microbial balance, dysbiosis, and overgrowth.- Discussion of intestinal microbiome and oral microbiome. 2. Gastric Anatomy and Mucosal Layers- The stomach: cardia, fundus, body, pylorus.- The gastric mucosa: epithelial lining, lamina propria, muscularis mucosae.- The epithelial layer: mucous cells, parietal cells, chief cells, enteroendocrine cells.- Beneath the mucosa: submucosa and muscular layers that contribute to gastric motility, mechanical digestion, and more. 3. Mucous Cells - The surface epithelium and gastric pits.- Secretion of thick, viscous mucus.- Protecting the epithelium.- The mucus traps bicarbonate ions: neutral microenvironment that protects against acid-induced damage. 4. Parietal Cells and Gastric Acid Secretion- Secretion of hydrochloric acid (HCl): denatures dietary proteins, sterilizes ingested food.- Parietal cells produce intrinsic factor: binds vitamin B12 to facilitate absorption in the ileum. 5. Chief Cells and Pepsinogen- Secretion of pepsinogen: activated by low pH into the proteolytic enzyme pepsin.- Pepsin and protein digestion.- Release of gastric lipase. 6. Hydrochloric Acid: Digestive and Protective Roles- Immune defense.- Pepsinogen activation.- Adequate gastric acidity essential for properly acidified chyme.- Priming release of bile and pancreatic enzymes. 7. The Small Intestine, Stomach, and Microbial Regulation- The pyloric sphincter.- The stomach supports minimal microbial diversity.- Acidic barrier aids in limiting the entry of opportunistic microbes into the small intestine. 8. Hypochlorhydria, Low Stomach Acid- Hypochlorhydria can compromise one of the body's defense mechanisms.- Colonization of the small intestine.- Insufficient pepsinogen activation and possible protein digestion impairment.- Suboptimal chyme formation and downstream digestive capacity.- Possible symptoms of hypochlorhydria.- Possible impaired absorption of micronutrients including vitamin B12, iron, calcium, magnesium.- H. pylori infection, autoimmunity, aging. 9. The Oral Microbiome, Intestinal Microbiome, and Dysbiosis- Oral and environmental microbes.- Altered gastric pH, bile, digestive enzymes, and more.- The oral cavity as the gateway to the GI tract.- Oral microbial species.- Oral hygiene and oral microbiome health. 10. Conclusion- Root-cause approach.Thank you to our episode sponsor:1. Shop ⁠⁠⁠⁠⁠⁠Fresh Press Farms⁠⁠⁠'⁠⁠⁠⁠⁠⁠Peach Cider Vinegar⁠⁠⁠ at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Vaginal dysbiosis is a state where the area of the vaginal canal and the vulva is experiencing a microbiome imbalance with amounts and types of micro-organisms out of balance.  The ph of the system changes and there can be unwanted physical impacts such as itching, burning, pain, discomfort among others. R30 is always a good combination skin remedy and remembering the body has a large skin organ and so remedies for the skin will often help for first aid, but going to a homeopath for constitutional remedies is preferred.  Looking at the narratives: 96, 99, 122 and 140 will compliment this episode to better understand many of the concepts.  If you are knew to homeopathy, I recommend narratives 2-5 to begin with before listening to any of the later episodes.  You can contact me at hownatureheals@gmail.com if you would like to further discuss homeopathic medicine and how it relates to nature. All views presented are based on credible sources, but they are explained through the individual's viewpoint.  Doing your own research while integrating new information is always important when forming your own viewpoint. The information in this podcast is not meant to address individual health needs, it is general in nature and should not be used as medical information for your health unless used in combination with your health practitioner.  

Nicole Rincon https://www.nicolerincon.comNicole's X https://x.com/NicoleRinconPARossignol Clinic https://rossignolmedicalcenter.comTACA Info: https://tacanow.org/wp-content/uploads/2019/10/F-H-2-Nicole-Rincon-Beginning-Biomed.pdfTACA Talks: https://www.nicolerincon.com/videosPublications https://rossignolmedicalcenter.com/articles-publications/#published-2024-2-articlesNicole Episode 1 https://www.youtube.com/watch?v=BBkdgwVfcZINicole Episode 2 https://www.youtube.com/watch?v=auLReV0DHkQDaylight Computer Company https://daylightcomputer.comuse "autism" in the discount code for $25 coupon.This is the future of tech.Chroma Light Therapy https://getchroma.couse "autism" for a 10% discount,***THIS IS NOT MEDICAL ADVICE***0:00 Nicole Rincon1:10 Daylight Computer Company; DC-15:33 Pre-pregnancy checks; Vitamin D8:37 MTHFR, Folate; Mitochondria; CPR, ESR, Inflammation11:12 GI; CSA; Bacteria, Fungus, Parasites, Calprotectin; Zonalin; MS & Proteus Mirabilis13:06 Organic Acid Test (OAT); Clostridia15:24 MTHFR; C677, 1298; Folinic Acid19:02 Folate's role in pregnancy and development; Critical info about types and duration22:35 Cholesterol; Maternal & Child; Speech & Communication25:06 Telepathy; Autism Rates26:40 Dysbiosis; PCOS29:30 Cholesterol ranges & symptoms; mood, irritability, cognition, aggression; Cortisol & Hormones37:02 Dysbiosis symptoms; Self-Injurious, Posturing41:08 Identifying symptoms in Non-Verbal; Self-Injurious45:08 Importance of Gut Health & Checks; Vitamin D, Electrical Efficiency & Biological Energy48:17 Autistics and pale skin; too many are pale; supplementing Vitamin D, K2; Brands51:00 Proprietary blends warning; abbreviated doses; Fungal overgrowth, Yeast55:49 "Binders;" Magnesium61:00 Fungal Overgrowth & Autism; OAT, Clostridia, C. diff, aggression, self-injurious; Antibiotics & Probiotics1:05:42 Telepathy Tapes, Autism, Water (Cytochrome C Oxidase), Coherence; Luc Montagier NOT Emilio Del Giudice; Distal Connections via Water and NOT axons; OutroX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Have antibiotics or heavy herbal antimicrobials decimated your microbiome and health? You may be missing critical species of keystone probiotics in your gut. Learn about the cutting edge keystone probiotic species offered uniquely in products developed by Systemic Formulas and Alimentum Labs, the sponsor of this podcast, and their role in regulating gut health and hormones, supporting the immune system and gut-brain axis, and keeping your skin healthy, with Dr. Shayne Morris, Ph.D., CNS, MBA. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes

Story at-a-glance Rising incidence of early-onset colorectal cancer is linked to changes in the gut microbiome, with specific bacterial strains producing mutagenic chemicals that contribute to cancer risk Global studies are underway to identify mutational signatures associated with gut bacteria, highlighting the significant role of dysbiosis in colorectal carcinogenesis Understanding the influence of gut bacteria on cancer development could lead to innovative therapeutic strategies, offering new avenues for prevention and treatment Research has identified a subtype of E. coli producing colibactin, a mutagen associated with cancer, suggesting that early exposure increases the risk of developing cancer at a younger age Dysbiosis, characterized by an imbalance in gut microbiota, is linked to colorectal cancer through mechanisms like genotoxicity, inflammation and oxidative stress, with specific bacteria such as Streptococcus bovis and Fusobacterium spp. playing a central role

On today's show: the 10 most important steps to restore your gut health after taking antibiotics. Although it's true that your microbiome will take a hit after antibiotics and may be permanently altered, it's still possible to offset some of the damage by supporting your gut during and after the antibiotic. We'd love to hear from you - send us a text!Thank you for being a part of our community! For the latest in digestive wellness go to https://gutbliss.com and follow us on https://www.instagram.com/gutbliss/ for more gut health info. Dr. Robynne Chutkan

A one-week course of antibiotics can remove up to 1/3 of your gut bacteria - and that damage can't be undone by just taking a probiotic, so you need to be absolutely certain that you really need that antibiotic. In today's episode, I'm going to share 10 critical questions to ask your health care provider if you've been prescribed an antibiotic that can help you limit the damage to your gut microbiome.We'd love to hear from you - send us a text!Thank you for being a part of our community! For the latest in digestive wellness go to https://gutbliss.com and follow us on https://www.instagram.com/gutbliss/ for more gut health info. Dr. Robynne Chutkan

In this episode, we detail the bidirectional relationship between the HPA axis and the intestinal barrier, illustrating how HPA axis dysfunction and cortisol dysregulation can impact intestinal permeability. We further discuss how intestinal dysbiosis can contribute to HPA axis overstimulation. Lastly, we detail some of the roles of short-chain fatty acids (SCFAs) and secretory IgA (sIgA) in this bidirectional relationship.Topics: 1. Overview of the HPA Axis and Gut Bidirectional Relationship- Chronic HPA activation, intestinal permeability, mucosalimmunity, and microbiome composition.   2. Components and Function of the HPA Axis- Hypothalamus, pituitary gland, and adrenal glands.  - Stress signals from the amygdala and prefrontal cortex, CRH release from the hypothalamus.  - CRH stimulates ACTH release from the pituitary.- Cortisol production and release. 3. Structure of the Intestinal Epithelial Barrier- The gut barrier consists of the intestinal lumen, microbiome, mucus layer, epithelial cells, and lamina propria.  - Specialized epithelial cells: goblet cells, enterocytes, enteroendocrine cells, and more.- The lamina propria contains immune cells, blood vessels, and lymphatics, supported by a smooth muscle layer.   4. Intestinal Permeability and Tight Junction Regulation- Transport across the intestinal epithelium: transcellular and paracellular pathways.  - Nutrient absorption and selective permeability.  - Tight junction proteins, such as occludin and claudins.   5. Cortisol's Impact on Gut Barrier Integrity- Cortisol can cross the intestinal microvascular endothelium and enter the lamina propria. - Chronic cortisol exposure and intestinal barrier function.- Increased permeability allows luminal antigens and bacterial endotoxins (e.g., LPS) to infiltrate the lamina propria.   6. Secretory IgA (sIgA) and Gut Immune Function  - Chronic cortisol exposure can reduce sIgA levels, weakening mucosal immunity.  - sIgA neutralizes pathogens, prevents microbial adhesion, and more.  - Lower sIgA levels increase susceptibility to dysbiosis and infections.   7. CRH and Its Role in Intestinal Permeability- CRH is produced in the hypothalamus and also peripherally.- CRH can stimulate mast cells, triggering histamine and inflammatory mediator release.  - Mast cell activation can increase gut permeability. 8. Microbiome's Influence on HPA Axis Regulation- Dysbiosis can disrupt HPA axis function.- IBS and sustained HPA activation.- Dysbiosis reduces SCFA production.  - SCFAs, particularly butyrate, support colonocyte health, tight junction integrity, and anti-inflammatory pathways.  - Inflammation and HPA axis dysfunction. 9. Root Cause Approach & Closing- Chronic cortisol exposure, CRH signaling, and gut barrier dysfunction.  - The microbiome influences stress response and HPA axis activity.  - Roles of SCFAs, sIgA, and tight junction proteins.- Addressing gut dysbiosis and GI-derived inflammation can support HPA axis regulation.  - Root cause approach.Thank you to our episode sponsors:1. Shop ⁠⁠⁠Fresh Press Farms⁠⁠⁠'Peach Cider Vinegar at Sprouts locations nationwide, and check out their full collection ⁠⁠⁠here⁠⁠⁠. 2. Shop the ⁠⁠Scalp Cleanser⁠⁠ and ⁠⁠Scalp Essence⁠⁠ from ⁠⁠T Stem Care. ⁠⁠3. Shop ⁠⁠⁠⁠⁠⁠⁠Ulyana Organics'⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Tallow Wild Yam Cream⁠⁠⁠⁠⁠⁠⁠, and use code ⁠⁠⁠⁠⁠⁠⁠CHLOE10⁠⁠⁠⁠⁠⁠⁠ 10% off your order.Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

TIME STAMPS:00:27 Phillip Meece was a COMBAT MEDIC who served in Afghanistan and returned with GUT DYSBIOSIS after his health was DERAILED by preservative-laden JUNK FOOD and ANTIBIOTICS. Today he no longer has any former symptoms of PTSD, DYSBIOSIS, ASTHMA, and ANXIETY! Phillip invented a PEMMICAN, HIGH FAT all-meat NATIVE AMERICAN FOOD that he remembered learning about in grade school.03:13 FLAVOR REVIEWS & INGREDIENT breakdowns: honey salted / zesty garlic / honey barbeque / salted !12:25 The SHIKIMATE PATHWAY: why consuming toxic plants high in fructose and glyphosate often leads to depression, anxiety, and withdrawing from civilization. 16:45 HYPERINSULINEMIA ( too much insulin in the blood ), the ROOT CAUSE to PCOS, ALZHEIMERS, BLINDNESS, and countless other shocking side-effects!17:58Why We Get Sickby Benjamin Bikman - Phillip's review and list of other recommended reading materials.20:03 What does “pemmican mean?!” Rendered tallow & the NATIVE AMERICAN PEMMICAN TRADITION!24:29 SUET - the raw, hardfat ofbeef,lamb ormutton found around theloins andkidneys; why it's popular!27:01 TALLOW vs. CACAO - beta oxidation and fat metabolism: why TALLOW is the most natural way we know of to directly burn visceral fat and reverse insulin resistance.33:01 COPPER & ZINC - two excellent reasons to include LIVER in your diet; cooking methods and other tips to make eating liver enjoyable!37:07 Lessons learned from eating RAW DEER BRAINS at 40 HOURS FASTED like a savage maaaaaaaaaaaaaan; HEART, TONGUE, KIDNEY, and other favorite organ meats.42:04 The value of home-made bone broth.47:11 Why we love living an ancestral lifestyle. 53:00 ARE YOU A WINNER OR A QUITTER ??? !!! Phillip's motivational business and lifestyle rant to follow your dreams even on the most discouraging days!55:06 Listener's inspiring success story (LISS) & podcast review - Andy the Scotsman-68! Carnivore life / IG @ andrew_6.8 57:02 BAD COACH CALLOUT OF THE WEEK! All about water retention and scale fluctuations, CICO, & GLYCATION.01:06:11 Friendly debate around whether fat or protein is more essential!01:12:02 CANCER-CAUSING PRESERVATIVES to stay away from in “seemingly healthy” fast foods & “grab-n-go” snacks.01:17:00 How to order Carnivore Bars! (see links below)Hungry for more??1. Check out RICHARDS KETO PRO PODCAST where Rich & Al Reeves, along with featured guests teach how to improve their health and wellbeing using a ketogenic diet.2. Stream Coach Colt's WORKOUT MOTIVATION SHOW calledThe SuperSetYourLife.Com Podcast from any platform.  ===============================================Questions for Coach Rich? Book a consultation (free and paid options available) with the UK's leading Keto nutrition expert HERE:Keto 1-to-1 Consultation – KETO PRO SHOP (theketopro.com)Questions for Coach Colt? Your first phone call is free for 15 minutes; I also offer 30 & 60 minute 1:1 consultations and monthly coaching services. Emailcolt@supersetyourlife.com or book here:https://calendly.com/ssyl/meet-greetWe PROUDLY sell KETO BRICKS™: https://supersetyourlife.com/collections/keto-brick%E2%84%A2Save 10% onCARNIVORE BARS with code COLT10

In this episode, we discuss the relationship between the intestinal mucus layer and secretory immunoglobulin A (sIgA), highlighting both as key components of the gut's first line of defense against pathogens, toxins, and environmental stressors. We detail how dysbiosis and microbial overgrowths can impact sIgA levels and can disrupt mucus integrity and function, contributing to increased intestinal permeability and inflammation. We then examine several additional factors influencing sIgA production. Topics: 1. Introduction: Importance of Secretory IgA and Intestinal Mucus     - Intestinal epithelial lining and its protective mucus layer     - Focus on intestinal dysbiosis and sIgA   2. Anatomy of the Gastrointestinal Lining     - Intestinal lumen, microbiome, mucus layer, epithelial cells, tight junctions, lamina propria, and smooth muscle     - Role of goblet cells in mucus secretion and epithelial integrity    3. Role of the Protective Mucus Layer     - Dual function of the mucus layer as a physical and biochemical barrier     - Composition of mucus: mucins, antimicrobial peptides, immunoglobulins    4. Goblet Cells and Mucin Production     - Mechanisms of mucin secretion and hydration     - Variability in goblet cell density across the intestinal tract     - Dysfunctions linked to conditions like IBD and IBS    5. Microbial Interactions with Mucins     - Glycan structures in mucins    - Roles of commensal and pathogenic bacteria in mucin degradation and mucus turnover     - Importance of regulated mucus production for gut homeostasis    6. Dysbiosis and Mucus Degradation     - Excessive mucin degradation leading to thinning of the mucus layer     - Consequences of increased intestinal permeability and inflammation     - Role of dysbiosis in disrupting the mucus layer    7. Overview of Secretory IgA     - Introduction to secretory IgA (sIgA) and its role in mucosal immunity    - Mechanisms of immune exclusion and pathogen neutralization    8. Production and Function of Secretory IgA     - sIgA production by plasma cells in the lamina propria     - Translocation of IgA through epithelial cells into the gut lumen     - sIgA binding to mucins and its immunological role in the mucus layer    9. Factors Affecting Secretory IgA Levels     - Possible contributing factors to low sIgA levels    - Implications of low and high sIgA levels for immune defense and intestinal health    10. Interactions Between Secretory IgA and Dysbiosis     - Cyclical relationship between low sIgA, dysbiosis, and infections     - Examples of overgrowths, like candida, disrupting sIgA     - Importance of addressing immune dysregulation to break the cycle    11. Bioindividual Root Cause Approach  - Factors to consider Thank you to our episode sponsors: 1. Shop ⁠⁠Fresh Press Farms⁠⁠' Peach Cider Vinegar at Sprouts locations nationwide, and check out their full collection ⁠⁠here⁠⁠. 2. Check out ⁠Spectrum Sciences⁠' Serums and The Vitamin B12 Protocol ⁠here⁠, and use code CHLOE15 for 15% off. Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

To have your question featured in a future video, please email: questions@drmdc.health Please include at least: Age, Weight and as much history as possible.

The largest study ever done on the human microbiome was published in 2018 by the American Gut Project. The goal of the study was to better understand the composition and function of the human microbiome, and the impact of diet, lifestyle and disease. The results provide an important roadmap for what to do to cultivate a healthy microbiome.We'd love to hear from you - send us a text!Thank you for being a part of our community! For the latest in digestive wellness go to https://gutbliss.com and follow us on https://www.instagram.com/gutbliss/ for more gut health info. Dr. Robynne Chutkan

After a holiday season filled with processed foods, sugary treats, and a break from regular routines, your child's gut health might be feeling the effects. In this episode, we explore how a gut reset can help restore balance and support your child's overall wellbeing as we head into the new year. We cover:> How processed foods and sugary treats can deplete the healthy bacteria in the gut microbiome and integrity of the gut lining, and how this can impact your kid's health.> The 4 most common signs that your child might benefit from a gut reset, and the link between gut health and skin flare-ups, mood and behaviour.> How we would approach a gut reset for children in 6 simple, easy to follow steps that will rebalance your child's gut microbiome naturally.If you're worried about your child's health and wellbeing, or simply feel like your family needs a little help returning to healthier habits after the festive season, this episode is packed with insights and actionable tips! Discover how to guide your child back to better gut health for a happier, healthier start to the year.Want a more detailed guide to our approach for resetting gut health? Our new 6 Steps to Better Gut Health course is exactly that! You can access this course here.Find out more about our '6 Steps to Better Gut Health for Kids' course + Get it FREE when you join us in the Natural Super Kids KLUB. This episode is proudly sponsored by my membership, the Natural Super Kids Klub. If you would like to become a member of the Klub to get more helpful resources to help you raise a happy and healthy family click here and pop your name on the waitlist. If you loved this episode, leave me a review! I would really appreciate it. Also, let me know your biggest takeaway from this episode by sending me a direct message on Instagram @naturalsuperkids or shoot me an email at jessica@naturalsuperkids.com.

In this episode, we go through the role of histamine within the gastrointestinal tract, exploring its regulation of gastric acid secretion and impact on intestinal motility. We examine how histamine-producing enterochromaffin-like (ECL) cells, mast cells, and gut microbiota contribute to histaminergic signaling, and how enzymatic degradation via diamine oxidase (DAO) maintains homeostasis. Additionally, we discuss histamine intolerance, highlighting the impacts of dysbiosis (as well as SIBO or small intestinal bacterial overgrowth) and intestinal barrier dysfunction on DAO insufficiency and histamine accumulation. Topics: 1. Introduction to Histamine & the Gastrointestinal Tract Role in digestion and motility Impact of intestinal conditions such as SIBO 2. Histamine as a Biogenic Amine Definition and classification L-histidine and histidine decarboxylase (HDC) Presence in various tissues, including the GI tract 3. Sources of Histamine in the Gut Enterochromaffin-like (ECL) cells in the stomach Mast cells in the lamina propria Histamine-producing gut bacteria 4. Histamine's Role in Digestion & Gastric Acid Secretion Interaction with parietal cells in the stomach Activation of proton pumps via H₂ receptor binding Maintenance of acidic pH for digestion Importance of proper pH within the stomach for protecting against pathogenic microbes Impact on downstream gut microbiota balance (e.g., SIBO) 5. Histamine & Intestinal Motility Modulation of gut motility via H₁ and H₃ receptors H₁ receptor activation leading to contractions (diarrhea, cramping) H₃ receptor-mediated inhibition of neurotransmitter release (bloating, slow motility) 6. Histamine Intolerance: Definition & Mechanisms Diamine Oxidase and histamine breakdown DAO secretion by enterocytes (intestinal epithelial cells) Enzymatic breakdown of histamine before absorption 7. Factors That Can Affect DAO Activity Genetic Polymorphisms: AOC1 gene, reduced DAO expression Cofactor Deficiencies: Copper, vitamin B6, and vitamin C as essential DAO cofactors Importance of intestinal lining integrity for DAO production Conditions leading to or associated with enterocyte damage Intestinal dysbiosis and histamine accumulation Intestinal dysbiosis & epithelial/enterocyte damage Suppression of DAO production due to epithelial dysfunction Small Intestinal Bacterial Overgrowth (SIBO) & Histamine 8. Symptoms of Histamine Intolerance Gastrointestinal symptoms (bloating, gas, constipation, diarrhea, acid reflux...) Systemic symptoms (dizziness, flushing, migraines...) 9. Identifying Potential Root Causes Tools and supplements Bioindividual approach Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more!

In today's minisode, let's explore the complexities of dysbiosis, commonly known as leaky gut, wit me as I explain how this condition can lead to systemic inflammation and a range of symptoms, from shoulder pain and eczema to fibromyalgia.  Discover how the immune system reacts to substances escaping from the gut and the potential for autoimmune responses. Learn why addressing gut health could be key to managing these widespread issues. This episode delves into the critical connection between gut health and overall well-being. Key Takeaways: Dysbiosis, also known as leaky gut, occurs when the gut membrane becomes compromised, allowing harmful substances to escape and trigger inflammation. The immune system reacts to these escaped substances, often resulting in widespread inflammation and autoimmune responses. Conditions like fibromyalgia and arthritis can be linked to gut health, highlighting the importance of addressing dysbiosis. Systemic inflammation due to leaky gut can manifest as shoulder pain, headaches, eczema, and brain fog. Improving gut health may lead to a reduction in autoimmune symptoms and overall systemic inflammation. If you've been listening to this minisode, and you're ready to take a timeout and focus on just you for a whole week, then I want to invite you to join me for the Transformation in Paradise Empyrean Retreat in Costa Rica May 24-31, 2025.  This will be the most transformative week of your life at the breathtaking Osa Peninsula in Costa Rica.  This will be a small group experience with exclusive access at the Blue Osa resort..  Imagine waking to the sound of the Costa Rican rainforest musical every morning.  Start your day with a yoga practice overlooking the Pacific Ocean, joined in with howler monkeys. Daily walks on a private beach that goes on for miles. Macaws flying overhead. Spa treatment at a 5-star resort, and the best farm-to-table food - right from the Blue Osa farm.   This retreat is designed to reset your nervous system, so you stop the patterns of self-sabotage and overwhelm. Reignite your motivation, release any addictive habits, and open yourself to the health, relationships, and financial abundance you deserve.  Intrigued? Curious? Let's book a call to find out if this retreat is the right for you.  Just head on over to ⁠sherryshaban.com/retreats⁠ and you can book a time with me there. Plus if you rate and review this podcast, giving me a 5-star rating on iTunes, and then send the screenshot to ⁠sherry@sherryshaban.com⁠, so I know who you are, you'll receive the voucher to join!  Remember, the group is small so spots are limited!  Let's see if Empyrean is right for you. Connect with Sherry Shaban: Get Your Free Food Freedom Workbook: https://www.makepeacewithfood.com Download HIIT Decks App Now!: http://www.hiitdecks.com Fall In Love With Fitness Podcast: http://www.fallinlovewithfitness.com YouTube: http://www.youtube.com/@sherryshabanfitness

Stephanie Seneff introduces Deutenomics, a groundbreaking field reshaping our understanding of biology and medicine. Discover how this revolutionary science could transform health and disease management. #Deutenomics #BiologyRevolution #MedicalInnovation

In this episode, we're diving into one of the most confusing and frustrating gut health topics: SIBO (Small Intestinal Bacterial Overgrowth). What is it really? How does it differ from gut dysbiosis? And, most importantly, how do you know if it's at the root of your digestive struggles? We'll unpack the three types of SIBO—methane, hydrogen, and hydrogen sulfide—what causes it to develop, and how conditions like hypothyroidism or insulin resistance might increase your risk. Plus, I'll share my personal experience with structural gut issues and how it shaped my approach to managing symptoms. We'll also cover testing options (hint: not all tests are created equal), treatment strategies that go beyond antibiotics, and why low-FODMAP diets aren't a one-size-fits-all fix. And if SIBO keeps coming back, don't worry—we're talking about how to support your gut so you can prevent recurrence and finally move forward. If you've ever wondered whether you have SIBO or just want a clearer picture of what's happening in your gut, this episode is for you! Let's get to the root of it together, apply for coaching here & we'll book a free 45-minute discovery call to get to know each other, dive into your history, & goals: https://girlsfuelnutrition.com/inquiry-form 

This episode explores three top topics from episodes in 2024: the mucus layer's protective role in maintaining gut barrier integrity, the bidirectional relationship between the microbiota-gut-brain axis and the hypothalamic-pituitary-adrenal (HPA) axis, and the importance of methylation and the MTHFR gene. During the first topic of discussion, we detail ways to support the intestinal mucus layer; as we approach the third topic of discussion, we highlight the impact of MTHFR enzyme activity on methylation, emphasizing its importance for many cellular processes. Topics: 1. Introduction: 3 Top Topics of 2024 2. The Protective Mucus Layer Over the Intestinal Epithelial Lining The intestinal barrier: intestinal lumen, microbiome, mucus layer, epithelial cells, lamina propria, and more. The mucus layer functions as both a physical and biochemical barrier. Goblet cells secrete mucins, which form the gel-like mucus layer, critical for maintaining barrier integrity. Dysregulation of mucus turnover can lead to increased intestinal permeability and inflammation. Supporting mucus levels: SCFAs, N-acetylglucosamine (NAG). Plant-derived mucilage and sources. 3. HPA Axis and Microbiota-Gut-Brain Interactions The HPA axis and the stress response. Microbiota-gut-brain axis. SCFAs produced by gut bacteria can influence gut barrier integrity and stress resilience. Dysbiosis disrupts SCFA production, weakens the gut barrier, and triggers inflammation. Dysbiosis and HPA axis dysregulation. Chronic cortisol secretion and secretory IgA. 4. The MTHFR Gene and Methylation Methylation involves transferring methyl groups. The synthesis of SAMe, the universal methyl donor: methionine and ATP with active folate (L-methylfolate) as a precursor. MTHFR gene polymorphisms reduce enzyme efficiency, impairing methylation and affecting DNA stability, neurotransmitter synthesis, and detoxification. Strategies, supplements, and more to support methylation. Thank you to our episode sponsor: 1. Check out ⁠Ulyana Organics'⁠ ⁠Tallow Wild Yam Cream⁠ and ⁠Healing Facial Oil⁠, and use code ⁠CHLOE10⁠ 10% off your order. Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

About the Guest(s): Dr. Kristin Hieshetter is a prominent voice in the field of functional health and wellness. Known for her comprehensive understanding of the gut-brain axis, Dr. Hieshetter has dedicated years to studying the connection between microorganisms and brain health. Beyond hosting "Functional Health Radio," she contributes to Functional Health University, imparting her knowledge on neurodevelopmental disorders, gut microbiota, and integrative health solutions. Dr. Hieshetter is celebrated for her evidence-based approach and commitment to changing global health trajectories through education and research. Episode Summary: In this captivating episode of Functional Health Radio, Dr. Kristin Hieshetter dives into the profound connection between the gut microbiome and brain health, a relationship crucial for brain development, immune system function, and hormonal balance. By examining the current research, she challenges prevailing notions about ADHD, autism, and other neurodevelopmental disorders, highlighting the pivotal role of gut health in these conditions. Dr. Hieshetter praises independent researchers who pioneer studies leading us away from pharmaceuticals and government-backed data, providing invaluable insights into the human body's interconnected systems. This episode unpacks the bidirectional communication between the gut and brain. Dr. Hieshetter weaves through complex concepts such as the role of neurotransmitters, immune pathways, and short-chain fatty acids, elucidating how gut microorganisms influence systemic health. Listeners are introduced to compelling clinical examples, emphasizing the life-changing potential of a well-balanced gut microbiome for individuals suffering from chronic ailments. Through an exploration of these themes, Dr. Hieshetter reinforces the episode's core message: "fixing the gut can fix everything," urging audiences to embrace probiotics for optimal health outcomes. Key Takeaways: Understanding the gut-brain axis is essential for improving brain development, immune function, and hormonal signaling. Gut microorganisms produce neurotransmitters and anti-inflammatory compounds, crucial for neurodevelopmental health, particularly in ADHD and autism. Dysbiosis, or bacterial imbalance, can lead to leaky gut syndrome and chronic inflammation, affecting overall health and brain function. Short-chain fatty acids produced by gut microbes play a pivotal role in healing gut epithelial injuries and regulating immune responses. It is imperative to choose high-quality probiotics from reputable sources to ensure their efficacy and impact on health. Notable Quotes: "If you're an adult who struggles with ADHD and have your entire life, it may have simply been the fact that your gut was not colonized with the right microorganisms when you were born." "Fixing the gut can fix everything." "Your gut interacts with your brain through various physiological processes." "When you have the right gut microbiome, you inhibit neuroinflammation in your children." "Please, for the love of God, do not get your probiotics from Amazon." Resources: Journal Reference: Protein Cell, May 2023 - Review article by Wang, Yang, and Liu. Functional Health University Erchonia Laser Research Functional Health Mastery Listeners are encouraged to explore the full episode for an in-depth understanding of how gut health influences brain function and to discover practical advice on improving overall wellness. Stay tuned to Functional Health Radio for more expert insights and transformative health discussions.

In this episode, we go through the interplay between the oral microbiome, the intestinal microbiome, and brain health, focusing on the mechanisms through which dysbiosis in these ecosystems influences neuroinflammation and central nervous system function. We explore the molecular pathways by which bacterial metabolites and inflammatory mediators from the oral and intestinal microbiota can disrupt the blood-brain barrier, activate glial cells, and impair neuronal processes. We also go through symptoms associated with microbial imbalance as well as oral health practices. Topics: 1. Introduction Focus on neuroinflammation, oral microbiome, and intestinal microbiome Oral-gut-brain axis. 2. Neuroinflammation Overview Inflammatory response within the CNS. Key cell types: Endothelial cells, neurons, glial cells (microglia, astrocytes, oligodendrocytes). Acute vs. chronic neuroinflammation and their implications. 3. Cellular Mechanisms Microglial activation and its role in cytokine and ROS production. Astrocytic contributions to neuroinflammation. 4. Effects of Neuroinflammation on the Brain Mitochondrial dysfunction and energy deficits in neurons. Blood-brain barrier (BBB) disruption and immune cell infiltration. Impacts on synaptic function and neuronal communication. Potential contributors - environmental toxins, sleep deprivation, microbial dysbiosis, infections, and more. 5. Role of the Intestinal Microbiome in Neuroinflammation Dysbiosis and the release of LPS by Gram-negative bacteria. LPS transport across the intestinal barrier (transcellular and paracellular pathways). Systemic inflammation and its impact on BBB integrity and CNS inflammation. 6. The Oral Microbiome and Brain Health Direct effects of oral dysbiosis on systemic inflammation. Indirect effects through oral-gut communication and intestinal dysbiosis. 7. Trigeminal Nerve and Oral Dysbiosis Role of the trigeminal nerve in sensory transmission. Interaction of oral bacteria with the trigeminal nerve via TLRs and LPS recognition. 8. Symptoms and Effects of Oral Dysbiosis Common symptoms Systemic effects on the intestinal microbiome and brain health. 9. Lifestyle Practices Oral health practices. 10. Conclusion Summary of the oral-gut-brain axis and its role in neuroinflammation. Importance of oral health in reducing inflammatory burdens. Thank you to our episode sponsor: 1. Check out Ulyana Organics' Tallow Wild Yam Cream and Healing Facial Oil, and use code CHLOE10 10% off your order. Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

In this episode, I share an in-depth look at a real 1:1 client session where we address the root causes of gut health struggles and metabolic imbalances. Using detailed GI testing and blood work analysis, we explore how dysbiosis, nutrient deficiencies, and thyroid function interplay with chronic symptoms like dry skin, constipation, and bloating. This case study outlines a systematic approach to healing, offering practical steps for anyone dealing with similar challenges.   Hosted by Leanne Vogel.   Coaching and other supports available at: https://shop.healthfulpursuit.com/  Podcast Sponsors, links and offers available at: https://www.healthfulpursuit.com/podcast/

In this episode, we dive into the interplay between the hypothalamic-pituitary-adrenal (HPA) axis and the microbiota-gut-brain (MGB) axis, highlighting their bidirectional communication through endocrine, immune, and neural pathways. We'll explore how gut-derived metabolites like short-chain fatty acids (SCFAs) and endotoxins like LPS influence HPA axis activity; conversely, we explore how dysregulated cortisol can impact gut barrier function, immune signaling, and more. We also discuss testing including stool analysis and DUTCH tests. Topics: 1. HPA Axis and MGB Axis Interaction The HPA axis and microbiota-gut-brain (MGB) axis are bidirectionally connected. Gut microbiota influences the HPA axis via metabolites and more 2. Overview of the HPA Axis and Cortisol Secretion Stress signals activate the hypothalamus to release CRH. Stimulates the anterior pituitary to produce ACTH. ACTH signals the adrenal cortex. The adrenal cortex releases cortisol, which binds to glucocorticoid receptors (GRs). 3. Cortisol Dysregulation Impact on Intestinal Health Intestinal lining anatomy: epithelial cells Tight junction proteins regulate nutrient trafficking and prevent pathogen entry. The mucosa contains epithelial cells, connective tissue (lamina propria), and a thin muscle layer. 4. Glucocorticoid Receptors (GRs) in the Gut GRs are intracellular receptors that modulate gene expression when activated. Cortisol binding causes GRs to translocate to the nucleus and bind DNA at GREs. GRs on epithelial cells. Modified tight junction protein expression. 5. Gut Microbiome's Role in HPA Axis Activity SCFAs, including acetate, propionate, and butyrate, produced by gut bacteria fermenting dietary fiber. SCFAs support gut integrity, reduce inflammation, and act as signaling molecules. A diverse and healthy microbiome can enhances HPA regulation via SCFAs. 6. SCFA Modulation of the HPA Axis SCFAs and cortisol. Research highlights SCFAs' ability to attenuate stress-induced cortisol increases. 7. Dysbiosis - Impact on the HPA Axis Dysbiosis reduces SCFA production, impairing gut barrier integrity and immune signaling. Dysbiosis, intestinal hyperpermeability and LPS. LPS activates inflammatory pathways. 8. Inflammation and Dysregulated HPA Activity Chronic inflammation and cortisol. Inflammatory signals from the gut exacerbate systemic and neural stress responses. 9. Symptoms of HPA Axis Dysfunction Chronic fatigue, disrupted sleep, mood disturbances... 10. Identifying Root Causes Dysbiosis, chonic infection / chronic inflammation... DUTCH Test Stool analysis Thanks for tuning in! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

In this episode, we examine the bidirectional relationship between intestinal health and immune aging, emphasizing how gut barrier dysfunction and microbial imbalances accelerate systemic inflammation and diminished immune function. Furthermore, we explore the effects of aging on intestinal barrier function, focusing on the decline in tight junction integrity, reduced mucus production, and impaired epithelial renewal, all of which contribute to increased gut permeability and chronic inflammation. Thus, restoring microbial diversity, supporting mucosal defenses, and addressing gut permeability are essential strategies to break this cycle and promote healthy aging. Topics: 1. Introduction: Immune Aging - Immune aging: a decline in immune function, increasing vulnerability to infections and chronic diseases. - The intestinal microbiome influences and is shaped by immune aging. - Microbial metabolites, epithelial integrity, and immune signaling are critical. 2. Anatomical Context of the Gut and Immune Cells - Gut layers: lumen, mucus, epithelium, lamina propria, and more. - The mucus layer protects the epithelium; function can become impaired with age. - Tight junctions prevent pathogen entry, while the lamina propria houses immune cells. 3. Mucus Layer and Goblet Cells: Role and Aging Effects - Goblet cells secrete mucins that form the protective mucus layer. - Aging can reduce mucin production, weakening the mucus barrier. - A thin mucus layer increases epithelial exposure and inflammation risk. 4. Microbial Interactions with the Mucus Layer - Commensal bacteria support mucus turnover by controlled mucin degradation. - Dysbiosis can disrupt this process, thinning the mucus layer. - Reduced mucus protection increases susceptibility to pathogens. 5. Effects of Immune Aging on the Intestinal Barrier - Aging effects on T cells, B cells, and inflammatory cytokine secretion. - Cytokines disrupt tight junctions and increase permeability. - Microbial products like LPS (endotoxin) cross the barrier, fueling chronic inflammation. 6. Dysbiosis and Its Role in Immune Aging - Dysbiosis reduces SCFA production and Treg activity. - Dysbiosis promotes chronic inflammation and accelerates immune aging. 7. Microbial Translocation and Systemic Effects - A weakened barrier allows microbial products to reach immune cells. - LPS triggers inflammatory signaling, amplifying systemic inflammation. - Chronic inflammation perpetuates gut dysfunction and immune aging. 8. Conclusion - Immune aging and intestinal health are interconnected in a feedback loop. - Aging weakens the gut barrier, while dysbiosis amplifies inflammation. - Restoring microbial balance and gut integrity is vital for healthy aging. Thanks for tuning in! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

Yeast overgrowth is a real phenomenon, and one that conventional doctors are often skeptical and poorly informed about. But yeast paranoia is also a real problem, and sometimes people have to be discouraged from adopting a too severe diet that isn't nourishing to their healthy microbes, or from over-treating for something that's not actually a problem anymore. This episode tells you exactly what to do to eradicate yeast and restore your microbiome. We'd love to hear from you - send us a text!Thank you for being a part of our community! For the latest in digestive wellness go to https://gutbliss.com and follow us on https://www.instagram.com/gutbliss/ for more gut health info. Dr. Robynne Chutkan

When it comes to treatment for SIBO, It's unlikely that you are going to be able to just take a remedy like an antibiotic and be cured. You have to pay attention to what's causing the microbial imbalance in the first place. In this episode we take a deep dive into testing for SIBO as well as a comprehensive approach to treatment that provides real and lasting relief. We'd love to hear from you - send us a text!Thank you for being a part of our community! For the latest in digestive wellness go to https://gutbliss.com and follow us on https://www.instagram.com/gutbliss/ for more gut health info. Dr. Robynne Chutkan

In this episode, we explore serotonin synthesis within enterochromaffin (EC) cells in the gut, detailing how tryptophan is converted into serotonin through enzymatic processes. We examine the role of gut microbiota-derived metabolites, such as short-chain fatty acids (SCFAs), in modulating the synthesis of serotonin including impacting tryptophan hydroxylase activity. We explore serotonin's interactions with receptors on enteric neurons and vagal afferent fibers, analyzing how these signaling pathways influence gut motility. Finally, we uncover conditions and symptoms associated with low serotonin production and the importance of the intestinal microbiome. Topics: 1. Introduction to Gut-Produced Serotonin - Serotonin production within the gut. - Serotonin's role beyond mood. - Synthesis, causes of low serotonin, related GI symptoms. 2. Gut Lining Structure and Cell Types - Layers of the gut lining, focusing on the mucosa. - Description of epithelial cells, including enterocytes, goblet cells, Paneth cells, and enteroendocrine cells. - Role of enterochromaffin (EC) cells in serotonin production. 3. Serotonin Synthesis in EC Cells - Location and function of EC cells. - How EC cells synthesize serotonin from tryptophan. 4. Biochemical Pathway of Serotonin Production - Step-by-step process: conversion of tryptophan to serotonin. - Enzymes involved, including TPH1 and AADC. - Importance of tryptophan availability in serotonin synthesis. 5. Storage and Release of Serotonin in EC Cells - Role of VMAT1 in serotonin storage within vesicles. - Controlled release. 6. Triggers for Serotonin Release - Physical triggers: mechanical stretch, pressure from food intake. - Chemical triggers: microbial metabolites, bile acids. - Receptors involved (GPCRs, TGR5) and signaling pathways. 7. Release of Serotonin into Intestinal Lining Layers - Serotonin exocytosis and interaction with nearby cells. - Release of serotonin on both luminal and basolateral sides of EC cells. - How luminal and basolateral release affects gut motility and barrier function. 8. Serotonin's Role in Gut Motility - Interaction with 5-HT3 and 5-HT4 receptors on enterocytes and enteric neurons. - Activation of the enteric nervous system (ENS) in the submucosal and myenteric plexuses. - Coordination with pacemaker cells for peristaltic movement. 9. Immune Function and Serotonin in the Gut - Effect on immune cells. 10. Gut-Brain Communication via Serotonin and the Vagus Nerve - Activation of vagal afferent fibers by serotonin. 11. Contributing Factors to Low Serotonin Production - Impact of dysbiosis and reduced SCFA production. - SIBO specifically. - Intestinal inflammation in general. - Imbalanced microbiota and inflammation can disrupt EC cell function. 12. Manifestations of Low Serotonin in the Gut - Effects on motility: constipation, dysmotility... - Common GI symptoms, including bloating, discomfort, and fullness. - Association with conditions like IBS. 13. Supporting Serotonin Production in the Gut - Painting a full picture and identifying root causes. - Strategies to foster a healthy gut microbiome. - Role of sunlight and tryptophan-rich foods in serotonin production. - Stool testing for microbiome imbalances. Thanks for tuning in! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

Dysbiosis refers to an imbalance in the microbiome – the trillions of organisms that live in and on your body, mostly in your GI tract. This imbalance can lead to overgrowth of some organisms, undergrowth of others, and a change in the metabolic activity of the microorganisms. That metabolic activity determines the byproducts that your microbes are making; things like hormones, and vitamins, and neurotransmitters that are involved in virtually all of your bodily functions. And that's why dysbiosis doesn't just affect your gut – it's associated with a wide range of problems, including autoimmune disorders, skin conditions, mental health problems – and more. In this episode: how and why we get SIBO.We'd love to hear from you - send us a text!Thank you for being a part of our community! For the latest in digestive wellness go to https://gutbliss.com and follow us on https://www.instagram.com/gutbliss/ for more gut health info. Dr. Robynne Chutkan

In today's episode, I interview Josh Dech. In our conversation, Josh discusses the critical role of gut health in overall well-being, emphasizing that gut health impacts not just digestion but various aspects of health, including fertility. He shares his journey from being a paramedic to a holistic health practitioner, highlighting the importance of understanding inflammation, dysbiosis, and the gut microbiome.    Josh challenges conventional medical perspectives on chronic diseases and discusses the significance of dietary choices, the role of probiotics, and the hidden threats posed by parasites. He advocates for a comprehensive approach to gut health, including the five Rs of gut health, and stresses the importance of working with health professionals for optimal results. Be sure to tune in!   Takeaways   Gut health impacts everything, not just digestion. Inflammation is a sign of the body wanting to heal. Dysbiosis is an imbalance in gut bacteria. Symptoms can indicate underlying issues. Diet plays a crucial role in gut health. Conventional medicine often overlooks root causes. All diseases have a root cause. Probiotics can be beneficial but vary in effectiveness. Parasites can significantly affect gut health. Working with a professional is essential for healing.   Guest Bio:   Josh is a Holistic Nutritionist specializing in Crohn's and Colitis, and other related gut issues. After reversing over 250 cases of bowel disease, previously thought to be impossible to fix, he's been connected to some of the world's most renowned doctors.   He's since been recruited to the Priority Health Academy as a medical lecturer, helping educate doctors on the holistic approach to gut health, and inflammatory bowel disease; and has launched a top 2.5% globally ranked podcast.   https://gutsolution.ca   https://www.instagram.com/joshdech.health/       For more information about Michelle, visit: www.michelleoravitz.com   Click here to get free access to the first chapter in The Way of Fertility Book! https://www.michelleoravitz.com/thewayoffertility   The Wholesome FertilityFacebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/   Instagram: @thewholesomelotusfertility   Facebook: https://www.facebook.com/thewholesomelotus/           Transcript:   Michelle (00:00) Welcome to the podcast, Josh.   Josh Dech - CHN (00:02) A pleasure to be here, Michelle. Thanks for having me on board.   Michelle (00:05) Yeah, I'm very excited to pick your brain. We just had a little pre -talk. I'm excited to really get into all the details of the gut nowadays we're starting to see just how impactful it is, but not just for digestion, which is like most of the time when you hear about gut, you think, okay, how's my digestion?   It's about everything. It's kind of like the center of everything. It impacts fertility.   But before we get into that, I'd love for you to share how you got into this work.   Josh Dech - CHN (00:36) I'd love to. Sure. You know, I think my entire career, I often like to describe it as a series of accidents just pushing me into one direction or another. And I used to be a paramedic and I loved it. You know, I love being in healthcare, but it wasn't very long until I realized it was actually sick care. It wasn't what I wanted to actually be doing. You know, I picked the same people up for the same things. Maybe 20 % of your calls were actually trauma, like car accidents and stuff like that. The other 80 plus percent was medical.   So we're talking people coming in for the same issues, heart issues, diabetic issues, strokes, very preventable things. Almost 99 % of them would be preventable through just simple lifestyle, nutrition and basic changes. And, you know, I ended up leaving that career after a short little stint and got into personal training in my early twenties. And that was more what I wanted to do. And I was a woman who came to see me at age 57, right at the beginning. And this is, this story is just, it'll knock your socks off because it really shows you what's possible.   So she's 57 years old. She came to see me. She was on 17 pills and a shot of insulin for breakfast. She had nine more pills and insulin for bedtime. So we're talking 26 pills a day, two shots of insulin. She had CPAP machine to sleep. She had high blood pressure. She was on disability at work as well on the list. So 27 floors up, but there was a fire. She had to stand there and wait for someone to come get her because she couldn't physically take the stairs. And that was the state of her health at 57. And so here we are two years later, she's 59 years old now.   Michelle (01:54) my God, wow.   Josh Dech - CHN (02:02) She's off all but two medications, no longer needs CPAP. She's no longer on disability, high blood pressure gone, it's totally normalized. Even her eyesight improved. She got her glasses prescription downgraded. And now he or she is 59 years old, Michelle, it gets even better. I told you, knock your socks off. We entered into her first weightlifting competition and she broke a world record in the raw power lifting federation in Canada at 59 from previously being on disability. And this is the power.   Michelle (02:14) Wow.   Yeah   Josh Dech - CHN (02:30) really truly the human body to go from 26 pills and insulin and disability to breaking world records right till she was in her mid 60s 62 63 when she retired from weightlifting but that's what the body can do it's consistently all the time it is working to heal you to improve you to rebuild you to build you stronger yet somehow we find ourselves continually going back the other way i'm getting it must be because i'm older it must be because you know i'm just getting sick it must be just genetic it must be this must be that   She was told all of her shit was genetic. None of it was. Her body was trying to heal her but it wasn't given the tools conditions and circumstances to do so until it was and then it did. And this is the power of we'll say holistic health is a super broad overarching spectrum but dealing with basics of nutrition and gut health and wellness at its root we can see that the body is so capable of healing itself and it's the most important thing you could ever do is give your body what it needs.   Michelle (03:01) Yeah.   Josh Dech - CHN (03:29) That's sort of how we got here.   Michelle (03:29) That is so powerful. Yeah, I that's so powerful because I, well, I think that the big thing that really gets in the way is kind of how we view our bodies or how we're taught to view our bodies. I want to say that we're conditioned to view our bodies because I think on an innate level, we do know that we can heal ourselves.   There's definitely like an innate knowing that you have and intelligence that you connect with with your body. But most people do not know based on how we're educated that their body can heal itself and that there is a choice outside of the 26 pills.   Josh Dech - CHN (04:02) Yes.   Yeah, right now you've been told there's nothing you can do right now you've been told your issues are genetic right now you've been told your only hope is medications to manage the symptoms there's nothing that can be done. But we need to understand as I learned throughout my career going back to school now specializing in gut diseases. Our guts really are at the epicenter of most of these things. And once you understand how it works, how it's connected, and how it's responsible for every aspect of your well being.   I argue sometimes that it well may be more important than our DNA. And once we can understand this concept, then we can start to look outside of what we think we already know, what we've been told. It unlocks a whole new, a whole new world for you. I'm singing a lot of it in my head now, a whole new world, but it opens all this stuff up for you. And then everything is possible. Everything you've been told becomes something of the past. Your whole paradigm begins to shift. And finally, you can look at yourself and go, wait a minute.   Michelle (04:37) You   Josh Dech - CHN (05:03) wait a minute, there, I don't have to be on these medications. I don't have to just deal with this. I don't have to just live with this because my body is trying to heal me. What is it trying to heal me from? And then you start unraveling. That's the thread that pulls apart the whole sweater.   Michelle (05:17) Yeah. And also inflammation is kind of at the heart of this because I know that it can impact so many things. know for fertility, it can impact your uterine lining. It can impact egg quality. it's very much linked with things like endometriosis. I mean, there's so many things and it just goes on and on and on. So let's talk about inflammation because that's really at the heart of all of this. Like when you address the gut health,   actually addressing inflammation. So talk about that. Talk about the Western approach to that and how you see inflammation occurring in the body.   Josh Dech - CHN (05:55) Yeah. Inflammation is always a reaction. Your body is healing you from something. And in the Westernized world, here's what I'll say. Imagine you're out going for a walk and you step on a nail and the nail goes right through your foot and you go into your doctor. The doctor looks at that nail and goes, wow, it is really swollen, really inflamed, but it's kind of just part of your body. Now there's nothing we can do about it. So what we're going to do is give you numbing cream for the pain. And if it gets infected, we can manage that as things get worse.   In worst case scenario, we'll just cut your foot off. That's absurd. may, you'd lose it. You slap the doctor, but here we are, we're going in and you got say a gut disease where I specialize like Crohn's, colitis and other gut disease. You go into your doctor, they go, wow, that inflammation is really bad. It's just genetic. It's part of your body. There's nothing we can do. We're going to manage it with quote numbing cream. So medication, anti -inflammatories. And when you get infected, we'll treat it as it comes up. And if worst case scenario, we'll just cut the organ out.   You should be slapping your doctor just like you would if it were your foot because it makes no sense. Inflammation, the very fundamentals of it is your body healing you from something. So let's apply this to Crohn's and colitis, right? Where I specialize is Crohn's, colitis and severe IBS. People are told it's genetic, it's autoimmune, there's nothing you can do. It is what it is. well, it will manage it or hopefully not cut out your bowels. Looking at this, it's not just genetic. It's not just autoimmune. It's not just unknown.   And I can break those down in about two minutes there, Michelle, really for you to basically, those are the three legs that Western medicine stands on to say you have to medicate it. I can break those with their own data and say it doesn't make any sense. But the idea being these inflammatory conditions we're told we're stuck with, yet we can reverse them 99 % of the time to full healing. Inflammation is your body healing you. We have to ask what is it healing you from?   So in the case of your intestines, they will, it's autoimmune and genetic, it's attacking your own body. Well, what if, what if your body is attacking something like your microbiome and your own tissues are caught in the crossfire, right? You get a nail in your foot, your body's not attacking your foot. That's not why you're inflamed. It's creating white blood cells or immune activity in response to attack the nail that's in your foot.   Michelle (07:50) Mm   Mmm.   Josh Dech - CHN (08:13) We don't question that. go, obviously it's infected. There's something that's wrong. When we get a condition like Crohn's or colitis or some other inflammatory condition, we go, it's attacking me. That doesn't make any sense at all.   Michelle (08:13) Mm   That's so interesting. So how do you see that specifically Crohn's is it the gut microbiome imbalance that's causing all of this? I think it's fascinating that you're saying this because I always talk about like symptoms being your friend. And it's actually just one of the intelligent aspects of your body to give you the alarm, to give you a heads up. Hey, pay attention.   Josh Dech - CHN (08:36) Yeah.   Mm   Michelle (08:52) So it is really fascinating to look at it that way rather than a nuisance.   Josh Dech - CHN (08:52) Yeah.   Yeah, I see it cascading down as a few different things. So number one, we all have dysbiosis now. Dysbiosis just means an imbalance in bacteria. But we know through the work of someone like Justin Sonnenberg that we can see what's called inherited dysbiosis. Our microbiomes are passed down from our mothers and her grandmother and her great, great grandmother before that. We get these dysbiotic states handed down and the more toxic our world gets them, the the dysbiosis becomes.   Michelle (09:06) Mm   Josh Dech - CHN (09:26) So think of it this way, Michelle, great, great grandmother, we'll just round number just to visualize easier. Say they have a thousand microbes. Great grandmother gives birth to your great grandmother, who's given 800, who gives birth to your grandmother, who gets six, to your mother, who gets 400, to you, who gets 200 microbes. You now have inherited dysbiosis. Of course your gut's getting worse, which explains the rise of gut disease we've seen over the last...   50 to 75 years, we've seen these numbers compounding gut disease getting worse in the 1950s, Crohn's and colitis. There was about, I think it was maybe five or 10 in 100 ,000 people had this disease. To the 1970s, you're now 25 to 40 in 100 ,000 who have the disease. 1990s, you're about 150. And now today, it's 456. Almost 5 % of people now have bowel disease in North America.   And so what we're seeing now is this continual growth from like whatever it was, 0 .0005 % to 5 % growth in bowel disease is because great great grandmother had a thousand, now you've got 200. This is inherited dysbiosis. And there's a direct correlation to the amount of pesticides we use, to the chemicals we put on our food, to everything. And now what happens, this dysbiosis, this is the moat around the castle. This keeps the bad guys out.   Michelle (10:39) Mm -hmm. Yeah.   Josh Dech - CHN (10:49) This is your defense mechanism. 90 % of your immune system is made there, or 70 to 90%, I should say, up to 90 % of your neurotransmitters, what your brain needs, all these leaks that happen in the gut when we're inflamed, it opens up the door for toxins to travel anywhere in the body through your lymphatic system or your bloodstream. And so we have our defenses lowered from 1 ,000 to 200, say. We don't have the same robustness to our body.   Michelle (10:54) Mm   Josh Dech - CHN (11:16) which means other invaders, mode is empty, invaders can enter the castle. So now we've got three big issues that really are the roots of bowel disease. Number one is going to be microbial imbalances. So this is that dysbiosis we inherited, which lets in overgrowth of fungus, which should be in our gut, but in smaller levels it overgrows. We see overgrowth of E. coli, a big one I see. Michelle has parasites. I'm talking three, four foot worms coming out of people, which yeah, which.   Michelle (11:20) Hmm.   Mm God.   Josh Dech - CHN (11:45) has never been detected and will never be seen on your blood work from your doctor. So we see microbial imbalances. We also see toxins which contribute to this number of 200. So pesticides in 1990, right, we had let's go back to the 50s. We talked about say five or 10 in 100 ,000 to 1990 where it was about 150 to today where it's almost 456 per hundred thousand people with bowel disease. In the 1950s there was a handful of pesticides for use.   1990s it was 700 to 900, today it's 18 to 20 ,000 different pesticides approved for use in North America. And so this is a direct correlation, also looking at processed foods and packaged foods and seed oil consumption, the decrease in natural foods like eggs and animal fats, the increase in these artificial foods that we're now taking in. I'm not even arguing are animal fats good or bad for your heart, what I'm saying is we've eaten less of them than ever before and have more diseases than ever before.   Michelle (12:39) Mm -hmm. Yeah.   Josh Dech - CHN (12:41) And so we have to look at these correlations and go, wait a minute, something is up. Now I'm a big fan of red meat and fatty tissues. I eat a lot of fat and a lot of meat and my body's amazing, my blood is great, right? But this is what we see, microbial imbalances, toxicity from foods, from the environment, from other places. And then we have again, a dietary nutrient deficiency. So diets, 60 to 80 % of the standard American diet is processed, refined. comes from a bag, a freezer, a box or a drive -through.   We have nutrients in our soil. Back in 2008, there was a study from the University of Texas who estimated you need eight oranges today to get the same level of nutrition that your great great grandmother would have out of one single orange due to tilling of the soil, the pesticides, right? Modern farming. So we have dysbiosis, which leads to toxins coming out or your toxins contribute to this as well. We have nutrient deficiencies because our food is more fake.   Michelle (13:22) Yeah, crazy.   Josh Dech - CHN (13:36) And then we have microbial imbalances overgrowing. No wonder your body's throwing a fit. Because since the beginning of time, whether you believe it was 5 ,000 years or 500 billion years, since the beginning of time, we've never had these issues. In fact, still today, the further away you go from the Western world, where we're eating all this food and covered in these toxins and these chemicals, the further away you go, the less disease you see. There's a direct correlation to living back naturally. Hunter gatherer tribes, they're like, what is infertility?   What do mean back pain? what are arthritis, Parkinson's, Alzheimer's, kidney disease, liver disease, diabetes. What are those? They don't skin issues, acne. These are things we call normal. They've never seen it before. And this is why this is how we get disease. Yeah.   Michelle (14:16) Yeah.   That is so crazy. I mean, it's really crazy. It's crazy to think about and it's crazy that this is acceptable and that there's no regulation and nobody's really protecting the health of the people. mean, enough is enough. Like it's just so frustrating because we, because people know that it's bad. They know it and they do it anyway. And, and in many countries, many of these pesticides are banned and they know that it can impact fertility. Now they're linking a lot of them.   Josh Dech - CHN (14:33) I hear you.   Michelle (14:50) So it's so frustrating. It's so frustrating for me to see my patients having to climb an uphill battle just so that they can protect their reproductive health. Like it's just crazy. And also it's interesting that you were talking about how the dysbiosis has passed on from situations or conditions such as Crohn's disease.   Josh Dech - CHN (15:03) Yeah.   Michelle (15:15) And it's interesting because like people would say, it's inherited, it's DNA. You would think that it's kind of the DNA, but it's actually, you're saying that it's the dysbiosis that's being passed on. I'm sure there's some level of DNA, like susceptibility as well, but that's kind of an interesting take or an understanding of it because you're like, okay, like that's not something that people thought about. And we know very well.   Josh Dech - CHN (15:33) sure.   Well, I'd love to...   Michelle (15:43) that the mother passes on her microbiome to the baby.   Josh Dech - CHN (15:48) She does. Yeah. I'd love to break those three things for you I could Michelle and just a matter of minutes. You know, we look at IBD Crohn's colitis. It's just genetic. It's autoimmune or there's no known cause. Well, we just talked about number one. These are the three pillars that stands on for your doctor to say it's meds for life or surgery. That's what they have.   Michelle (16:06) So you're saying this is the perspective of medicine, what you just said. Yeah. Yeah.   Josh Dech - CHN (16:11) Yeah, sorry, let me clarify. So if you've been diagnosed with Crohn's colitis or even IBS, you've been told it's genetic or it's an autoimmune condition or there's no known cause. That's what your doctors told you to date. And they say your best bet is medication or surgery. That's your only hope. What I'm saying is none of that makes sense. And I'll tell you why idiopathic means no known cause. We just talked about seven different causes inherited dysbiosis increase in toxins and chemicals. The last hundred years we've had   80 to 100 ,000 new chemicals added to our lives, most of them in our food. And so what you put in your gut, you're going to tell me doesn't affect my gut. That's nonsense. That's number one. So there has to be a cause because we've seen cases, even looking at the data per CDC, about 3 million cases worldwide in 1990. Today it's seven to 8 million. So cases have doubled, almost tripled in the last 30 years. So there has to be a cause. So it can't be unknown. Like they say it is number two.   Michelle (17:08) Yeah.   Josh Dech - CHN (17:11) They say that it's just genetic. Well, 50 % of those seven or eight million cases, North America is less than 5 % of the population. They have 50 to 60 % of all the world's cases of bowel diseases. So when 5 % has 50 % in the last 30 years where it's blown up, it cannot just be genetic. That would take thousands of years and most of those things weed themselves out of the gene pool. The last one is it's autoimmune.   Well, looking at the actual antibodies per studies, the ones that we see, even like P. Anka, we call it. This one, 70 % of those with ulcerative colitis will have this antibody. Well, it can be caused by mesalamine, a drug they use to treat Crohn's colitis, by stress, by fungal infections, by other bacterial overgrows, antibiotics. These antibodies, only 40 to 60 % have any antibodies at all. And the ones that do,   can be very well explained by nearly anything else that can go on inside the body, such as dysbiosis states, parasites, infections, antibiotic use, the very drugs in Miran, azathioprine, the ones they use to treat Crohn's and colitis can cause these antibodies. So it can't be autoimmune. And even if it was truly autoimmune, at least 50 % don't have any antibodies at all, but you're treating it like it's autoimmune. So the three pillars they have to stand on, Michelle, to say you need drugs for the rest of your life.   Michelle (18:23) Wow.   Josh Dech - CHN (18:34) There's no hope for you. Your life is basically ruined. It's management or we cut the organs out. None of it makes any sense by their own data. And this, this little perspective shift changes everything.   Michelle (18:41) No.   My God, this is so important. It's so important that people hear this because I think that we just take it for what it is for truth, absolute truth. When we go and I've had, I've had the same situation for my irregular periods, but you know, it could be anything. And then you're going and you get an answer that, you know, just doesn't seem to feel right. And you talk about the possibility to cure diseases. Can all diseases be cured?   Josh Dech - CHN (19:12) Yeah, it's really interesting because I like to throw that question out there because the word cure is sort of a dirty word in the Western world. It's not something they are. And most doctors are because it's a huge claim to make. I cannot legally in my practice, because I'm not a medical doctor, right? I work with doctors, I'm a physician's consultant, and that's all great, but I'm not a doctor. I cannot legally use the words cure, treat, or heal in the context of what I do. But what I can say is this.   Michelle (19:20) Yeah, people are afraid of it. Yeah. Yeah.   Josh Dech - CHN (19:43) I believe all diseases have a root. Disease is not innate to your biology or DNA. We even talk about genetics, right? Let's go back to the genetic weak link of bowel disease. Sure, you get five people in a room, Michelle, you expose everybody to mold. One gets really bad periods. One gets Crohn's or colitis. One gets asthma. One gets Parkinson's disease. Another one gets nothing. Because when your genes are exposed, say dysbiosis, it puts stress on the genetic links, the genetic chain.   When you're toxic or infected, it puts stress. There's a study called neutrogenomics, which is nutrients and genetics and their correlation and reactions together were depleted. So these genes are getting stretched and pulled on the chain. The weak link is the one that snaps first. So there's no doubt there's a genetic component to bowel disease or what you're dealing with, but there are things that are stressing that chain. If you can pull down the stress and give your body what it needs to simply function normally, you're going to be just fine.   Michelle (20:28) Mm.   Josh Dech - CHN (20:42) Your body's gonna do what it has to do. It's gonna heal itself. And these quote genetic conditions sort of just go away because they were never really genetic. It was just exploiting what may have been a weak link. You go, well, I had my gene tested. I've got the MTHFR, so I can't methylate. I can't do this. Every form of natural nutrients that comes from the soil, that comes from animal meat, that comes from the earth in any way, your body will use a methylate.   It's all the artificial or fortified versions. It's the folic acid. They spray on the grains and crops. It's not the actual nutrients from earth. It's the artificial stuff you can't use. So don't beat yourself up about it. Just grow your own food.   Michelle (21:11) Mm -hmm. Right. Correct. Yeah.   Ooh, I love that. It's so true and it's so nice to hear it put in that way for people listening to this that's a huge issue for a lot of people trying to conceive because for so long, they've been having folic acid and also if they're eating grains, even if they don't want folic acid, it's kind of like shoved in our faces. So we're forced to eat it. Yeah.   Josh Dech - CHN (21:41) Yes, and folic acid is basically poison. I mean, we know, right? Tested like MTHFR, popularized gene, there's a snip in there, changes your morphology, how your genes will activate. 44 % cannot use folic acid, but doctors give folic acid to 100 % of women who are pregnant. Why? If you can't use the folic acid, it actually can cause blood pressure issues. It can cause all kinds of issues, cognitive impairment, anxiety, depressive issues, gut issues.   Michelle (22:02) Yeah.   Josh Dech - CHN (22:10) probably fertility issues, right? I can't speak to that one specifically, but I would guess through the chain of events. Well, there you go. So you're being given a drug that almost 50 % of the population can't, I call it a drug because it's artificial, that you cannot use that can cause other health complications. Well, no wonder you have gestational diabetes. No wonder you have hypertension. No wonder you have these, you know, prenatal conditions. The Western world treats pregnancy like a disease state. You are sick. We have to treat you, but it's not.   Michelle (22:14) Yeah, yeah, it does. For some people, yeah.   Yeah.   Yeah.   Josh Dech - CHN (22:40) In the inflammatory markers you get from pregnancy, all these different things, they're actually normal and they're actually a biological beneficial process, which is also connected to your gut, oddly enough.   Michelle (22:52) Everything's connected to your gut. So talk to us. It really is. The more I do this, the more I realize this. It's kind of like just everything's the center. Even Chinese medicine, the spleen and stomach are the digestive couple. And every couple, there's like a yin and yang pair of organs. Every one of them has a different direction. The spleen and stomach is the center. It's kind of like where everything comes from.   Josh Dech - CHN (22:54) All of it.   Mm   Michelle (23:20) So it really is so important and that's, it really comes down to your gut health. So talk to us about like what people can do and really how like kind of take us through like the inflammatory process or the anti -inflammatory approach to your gut.   Josh Dech - CHN (23:38) Yeah, first thing is we just have to remove the nail. That's it. You know, your body is reacting to so much and I describe it like this. Picture your body's like a cup of water. I I got a cup of water next to me here. So picture this cup gets full and fuller and fuller. As the cup starts to fill up, you start to develop symptoms. I'm having menstrual issues. I'm having PMS. I'm having some infertility. I'm having some skin issues. I'm not sleeping. I'm having anxiety, depression, gut issues, et cetera. These are the symptoms you develop.   Michelle (23:41) Mm   Josh Dech - CHN (24:07) Now when that cup finally overflows, you now go into your doctor and they say, you have this disease. Cause they're looking at everything that's gotten wet. go, yep, this is just a condition you have. The floor is wetiosis. All right. And they go, this is just what it is. We don't look at what led to it. We don't look at what contributed instead. We go, yep, it's just part of your disease process. It's part of your body. Here's some management for your symptoms. This is numbing cream on the foot. That's what it is. Rather than taking the nail out.   Michelle (24:07) Mm   Josh Dech - CHN (24:35) And so we're looking at disease, understand something's filling your cup. And this is how we can begin reversing it. Number one, we have to look at one, what is filling the cup? So this is going to go back to your environment, back to your gut, your microbes, that when the defenses came down, the moat was empty. What came into the castle? That's number one. Number two, how do we drain the body? Cause everyone talks about detoxing. You'll hear 10 day detox, seven day detox, 24 hour detox is always something to sensationalize. But there's all these detoxes.   Michelle (25:01) Mm   Josh Dech - CHN (25:04) Yes, your body is detoxing constantly on its own and yes, sometimes it can use some support. There's a good reason for that. But something we often miss is called drainage. Detoxing is gathering the trash. Drainage is bringing it out to the curb. So yes, your liver, your kidneys, your bile ducts are one that most people miss, gallbladder and bile ducts. That's one of the most crucial parts of healing and inflammation. We have to look at your skin, your sinuses, your lungs.   Michelle (25:19) Mm   Josh Dech - CHN (25:31) Lymphatics, even your blood, these are all drainage or detox pathways. They help move and transport and organize toxins, but also get them out of the body. So sinuses, skin, lymphatics, et cetera. This is drainage. If we don't have this properly supported, I don't care how many parasite protocols you take or antifungal meds you take or how many detoxes you do. If it's not getting out of the body, it's just moving or it's still collecting. And so it's continuing to fill your glass. Right?   Michelle (25:56) Right.   Josh Dech - CHN (25:58) Your doctor looks at all the things filling up your glass. They don't use it to figure out what's happening or what's causing it. They use it, what's called diagnostic criteria. So they are looking simply to check the symptoms, do their tests in order to meet what fits this box. Once you have enough checks to color in this box, we then can give you these drugs in this order. If they don't work, snip, snip, here's your surgery. And the idea is again, disease is innate.   Michelle (26:23) Mm   Josh Dech - CHN (26:25) You just have these symptoms, therefore you just have this condition. There's nothing we can do. And here's how we'll manage. Rather than looking at your symptoms that led to the disease in reverse engineering the process, what is filling your glass and preventing it from emptying? If Western medicine did that, they'd be bankrupt, which is probably why they don't. Because you're talking the three biggest industries, Michelle, in North America are healthcare, so hospitalization, health insurance, and pharmaceuticals.   It makes up 18 % of the entire US GDP. So 18 % of the entire income of the United States of America is healthcare. Yet they are the sickest country on earth. Six out of 10 adults have some kind of chronic illness or chronic inflammatory condition. Six out of 10, it's $4 .7 trillion a year to manage disease. It'd probably be more like 50 to 100 billion. So pennies on the dollar really, if you actually cured everything.   So there is a huge financial incentive to not actually hear anybody. That's messed up.   Michelle (27:26) That's so crazy. I mean, I think it's so messed up. I mean, it's really messed up. think a lot of people know this and there's definitely a lot of money moving around between the food industry and the pharmaceuticals, which I mean, you know, like why.   Josh Dech - CHN (27:44) Yeah, yeah. You get a CEO who goes from Bayer Monsanto, who by the way, just paid out $11 billion with a B, $11 billion in lawsuits because their glyphosate product caused so many cases of cancer. There's over a hundred thousand lawsuits pending. They paid it over 11 billion with another 30 to 40 ,000 lawsuits still pending. And guess what? They're still allowed to use the product. Even though it's been proven hundreds of thousands of times to cause cancer and other dangers.   because super unethical, we live in a horribly unethical system based on lobbying. Get one more for you. There's a chemical called chlorpyrifos. It's an organophosphate. Organophosphates are nerve agents. If you've ever heard of sarin gas, for example, used in the Tokyo subway attacks in the eighties in Syria against the Halabja people, it's a nerve agent. It is a toxin, organophosphates, particularly sarin gas.   Michelle (28:15) It's so unethical.   Yeah.   Mm   Josh Dech - CHN (28:41) Well, there's 800 plus organophosphates of the same class, these nerve agents that are used on our food. One recently was re -approved for use called chlorpyrifos just back in November 23 or December 23, was re -approved for use. Well, this was being explored in the 1930s and 40s by Nazi scientists as chemical warfare on humans, but they put it in our food. Then you get people going, well, the poison makes the dose. Okay, I get that. Yeah, if it was.   Michelle (28:47) Mm   man.   Josh Dech - CHN (29:09) microns of chlorpyrifos, your body would get rid of it. But we got over a billion pounds of chemicals every year on our food that we consume. We've actually consumed now four times more pesticides per person than we used to in the 90s, because there's so many more of them. The poison that know, the dose makes the poison. Yes. But we've also 17 times our dose, of course, we're so toxic, of course, everyone's poisoned. And so these are the things we have to consider.   Michelle (29:34) Yeah.   Josh Dech - CHN (29:37) But circling back, these are the toxins contributing to your glass filling up. So you want to empty the bathtub, turn off the tap, right? So let's put a hole in the toxins. Simple as the clean 15 and dirty dozen list from the EWG, Environmental Working Group. Go organic where you can, or just don't buy it, right? There's a lot of other ways. It doesn't have to have the organic label. I don't buy all organic. There's a farmer's marketing in my house.   Michelle (29:45) Yeah.   Right.   Josh Dech - CHN (30:02) And I talked to the farmers, they do one fungicide spray at beginning of the year on the ground, and then all their crops grow. That is a risk reward ratio I'm willing to accept. It's the same price, but there's one spray instead of the average strawberry has like 12 pesticides on it. And so that's what I'm willing to accept for myself. And I will adapt to the rest. And so turn off the tap, start changing out the toxic environment, start making some of these better modifications. One of the top toxins or pollutants for humans is actually recirculated indoor air. Open your windows.   Michelle (30:03) Mm   Mm   Josh Dech - CHN (30:32) Just where you can, open them up, let some fresh air come in. And this we can start, this is turning off the tap. Then we can open our drainage and detox pathways. And then we can begin removing the invaders that came into the castle. And then we can begin repairing and rebuilding the walls and everything that was destroyed after these invaders came in. That's sort of the process affectionately typically referred to as the five Rs. There's sort of an acronym we can use in there for that, but that's the idea.   Michelle (30:33) Hmm, yeah.   Yeah. And a lot of people just say, then I'll just get probiotics. But then I, I'm learning, you know, that not are created equal. So I wanted to get your thoughts on that. Like I just, the different types of probiotics, everything comes out. Another company says, ours is special because of this, that, and the other. Then there's a spore based probiotics, which are more likely to survive our entire tract. So.   Josh Dech - CHN (31:04) Mm.   Yes.   Michelle (31:26) I'd love to pick your brain on that.   Josh Dech - CHN (31:29) I'd love to sure. So spore based probiotics, they're more like seeds, and they're typically coded to get to the large intestine. This is where 90 % of your intestinal bacteria actually live is in the large intestine right where it connects to the small intestine and that whole area there. That's where most of them live. And so the spores will get there the like seeds that plant and grow trees that bear fruit. We have other probiotics, which you're right, not all are made equally, a lot of them will come in, they're dead, but you still can get benefits. If you think about   Let's go to pro, pre and post biotics, right? The three things I think we often get mixed up. I think of it like fish in a fish bowl. Probiotics are the fish, the living organism that swim around in the bowl. Prebiotics are fish food and postbiotics are what the fish poop out. If you look at your bacteria the same, they're your fish in your fish bowl, the living organisms, the probiotics are the fish. This is what moves around and engages with your body. They do so much for you. They produce vitamins and minerals and nutrients.   Michelle (32:04) Mm -hmm. Mm -hmm.   Josh Dech - CHN (32:28) help balance hormones and detoxify and help with your immune system. They do all kinds of great things, mostly through how they signal to the body. But then your prebiotics are what they eat. So this is going to be your fibers, it's going to be your carbs and starches, some proteins, there's going to be some things that they will consume, which creates the post biotics your body likes, the short chain fatty acids and minerals or the vitamins and all these things. And so we consume probiotics, a lot of them we eat are dead.   So you're still getting the postbiotic or the bacterial poop, if you will, of all the benefits, which come in, come out in a couple of days. It might be very short term and they're kind of out the door, but along the way they can have a lot of really good beneficial signaling to the body, to the immune system. It's like a radio signal. They come in and out beep, beep, beep, beep, they send signals back and forth. Your body makes changes. On the other hand, what a lot of people don't recognize is maybe if you have a condition like SIBO, small intestinal bacterial overgrowth,   Michelle (33:00) Mm   Mm -hmm.   Josh Dech - CHN (33:25) you have a bacterial overgrowth. Sometimes adding probiotics in, there are classes of bacteriums called bacteriocins, which will kill bacteria. So they might be beneficial in SIBO. For example, lactobacillus reuteri or rooteri, call it tomato tomata. But this one can act as a bacteriocin has been shown in clinical to be beneficial in a lot of cases for SIBO to reduce the bacteria. On the other hand, some might contribute to the problem. I had a client with parasites.   Michelle (33:42) Mm   Josh Dech - CHN (33:55) And she was consuming a lot of probiotics, which were higher in histamines, which contribute to the issue because parasites also can create histamine issues. Even bone broth was bad for her gut because it's high in histamine. And so it made her issues worse. so considering we got probably a thousand, maybe 2000 species, seven to 9 ,000 strains of bacteria makes 15 to 20 million different bacteria. In fact, there's a hundred, think it's 130 times more DNA in your gut bacteria.   Michelle (34:07) Mm -hmm, right.   Josh Dech - CHN (34:25) than you actually have in the rest of your body. 23 ,000 genes or so in your human genome, 3 million genes inside of your bacteria. So you take this handful of probiotics out of 3 million different genetic strains, it's like a grain of sand on a beach. It may help, it may not. I wouldn't rely on them as a fix all. And there's a lot of ways in there where you can actually cause more problems. You could put black sand on a white beach and you're gonna notice it until it gets mixed in and disperses enough. It can create a problem. And so we have to really   Michelle (34:39) Yeah, yeah.   Josh Dech - CHN (34:54) keep an eye on what we're putting into our body. I think throwing probiotics in sort of willy -nilly can lead to a lot of issues.   Michelle (35:02) Yeah. What about a Sporebase, which are better for SIBO? What are your thoughts on that?   Josh Dech - CHN (35:07) Well, spore based, see they're better for SIBO. I've heard that as well. I think my initial thought is look, they get to the large intestine, less so the small intestine. So we're not contributing to the small intestinal issues. But one of the contributors I do see of SIBO, for example, would be parasites. They tend to hang in the bile ducts, like we talked about there, the all important drainage pathways in the liver of the appendix and what's called the ileocecal valve. So right where your small and large intestine will actually connect.   Michelle (35:16) Mm   Mm   Mm -hmm.   Josh Dech - CHN (35:37) Parasites can hang out in these issues actually messing with your valves. So even if you have spores going into the large intestine, they can still backflow because the valves will say are broken or jacked up can get into the small intestine. And a lot of SIBO conditions are fecal microbes. So large bowel microbes getting into the small intestine where they should not be. And these areas can cause a lot of problems now too. So I don't know if I'd say they're better for or maybe just less bad then, but maybe it can contribute to the problem. It's hard to say.   Michelle (35:40) Mm.   Mm -hmm.   Mm -hmm. Yeah.   Josh Dech - CHN (36:07) But ultimately, know, SIBO is a really nasty condition to have to deal with, but I've seen it as one of the roots that can develop into Crohn's or colitis as well, other bowel diseases.   Michelle (36:17) Wow. And what about parasites? So what are some of the things that you can do to, because a lot of times you won't see that in like more generic tests.   Josh Dech - CHN (36:27) Yeah, they're very difficult to detect parasites. Even some of the best testing you'll get for stool testing, you're 40 % accurate unless you're finding ovum, live worms or protozoa eggs, et cetera. You know, there's about a million different types of parasites estimated that are available on planet earth. About 1400 can infect humans and you know, it's like, well, I've taken ivermectin or I've taken babendazole or fembendazole some kind of Zol, which is supposed to be good for parasites and they can be.   Michelle (36:35) Mm   Josh Dech - CHN (36:55) But of the 1400 types, you might not be targeting more than three or four. And again, if your drainage pathways aren't open, you're not really going to be successfully clearing stuff. And so we're looking at parasites. say testing is relatively inaccurate. We have to go by symptoms and even blood, blood chemistry. It's not something I'm an expert in, but I do know people who are very proficient in what's called functional blood chemistry. Well, they'll look at your blood work and go, definitely you have a parasite and here's where I think it is or what type I think it is, which   To me is like wizardry. I just have no idea. I'm not that good at blood work, but it's really amazing art. so testing is not amazing for them. Most doctors believe parasites are a third world problem because that's what they were told 20 years ago in med school. But look what we have, the level of immigration we have, the level of import export we have, the level of accessibility for traveling all around the world that we have. Maybe if they used to be, but they're everywhere now to the point where if you've got a pulse, you probably got a parasite.   Michelle (37:32) Mm   Mm   Josh Dech - CHN (37:51) The question is, it causing you a problem right now or not? Because parasites, fungi, bacteria, viruses, they all live in harmony in a healthy gut. With great great grandmothers, 1000 microbes. But now we've got 200 microbes, this dysbiotic state, these opportunistic parasites or fungi or bacteria now overgrow because they have the room to do so. Nothing's keeping them in check. And now they're a problem. So this isn't to say parasites are all bad. Sometimes they're very, very good.   Michelle (38:19) Mm -hmm. Mm -hmm.   Josh Dech - CHN (38:21) but they're now becoming problematic because we're all so sick.   Michelle (38:24) So what do you do and what are some of the symptoms that people can have?   Josh Dech - CHN (38:28) so many. So we look at parasites, again, going through symptomatology, I like that we bring this through, because symptoms often speak louder than testing. That's something you have to keep in mind. Again, a parasite test at 40 % accuracy can come back negative 10 times in a row. So we have to look at, you know, abdominal pain. Do you have pain when you palpate or press around the liver, the gallbladder? Do you have all your organs? So looking at tonsils, appendix, gallbladder, if you've lost those, there may be a parasite route.   Michelle (38:38) Mm   Mm   Josh Dech - CHN (38:58) back pain, hip pain, like joint pains, seasonal allergies or other allergies that seem to come up. If you have gut issues and gut symptoms, for example, that may be come and go. So every couple of weeks up and then they're down or seasonally, for example, this could be parasites due to their life cycles, high cholesterol or liver enzymes that are elevated, frequent sinus infections, anemia, because parasites will actually eat iron. They can eat   like lungs, liver, kidneys, they can eat iron, they can eat lymphatic fluids if you've got lymphatic issues, mumps chronically, tonsillitis chronically, these can be parasitic issues in nature. Even infertility. Parasites love especially female reproductive organs. So PCOS can sometimes be a parasitic issue at the root or a metabolic issue which may have a parasitic component because parasites can get to these areas in your body.   actually encapsulate them in a cyst or a tumor, hence cancers, which is actually a protective mechanism or thought to be protective, where it's trying to enclose these things in rather than DNA mutating and causing a problem. We can have anxiety, depression, hair loss, early hair loss, liver enzymes are elevated, think I mentioned that, psoriasis, eczema, really classic symptoms, rashes and hives, that's just a handful. There's probably 50 or 60 symptoms that could be parasites.   but we have to go back to context. You know, have rashes and hives, okay, well could be something else. There could be parasites. Let's look at the rest of the symptoms. I'm not saying if you have one of these things or all these things, I mean, if you have all these things, probably parasites, but if you just have a few, it could be something else, but I wouldn't rule parasites out.   Michelle (40:34) Mm   And what do you usually do to treat them?   Josh Dech - CHN (40:43) Great question. This is something that can be very finicky. Again, a lot of people I talk to, you're hearing this going, I've taken a parasite protocol, I've done a cleanse, it didn't help. You're trying to evict tenants from the building. Are the doors unlocked? And so if you're trying to get rid of parasites, is your drainage open? So we have to work on drainage support. What we do with clients, it's a combination of a lot of things. There's supplementation, there's nutritional, there's lifestyle. Sometimes it's a combination of acupuncture enemas, like coffee enemas.   Michelle (40:57) Mm   Mm   Josh Dech - CHN (41:13) There's a lot of different things we can utilize the open drainage pathways, but everyone's different. And it's something that it really should be done on a supervision. I know you're hearing this right now. Go, I can do that. I can do acupuncture might help you. It might not. It is, but I don't want you putting yourself in the hospital. I have to say that because we can move too many toxins too quickly. You can actually create a commonly known Herc's Heimer reaction, Herc's H -R -X. And this Herc's Heimer reaction is just   Michelle (41:13) Mm   Mm   Yeah, that's important.   Yeah.   Josh Dech - CHN (41:41) Basically, you're taking too many toxins, you're mobilizing them and your body can't get rid of them properly and you're making yourself very ill. So this is definitely a professional supervision issue, but these are things we can do. So number one is drainage in tandem with or post actually getting rid of or reducing your toxic loads for no longer, right? Turn off the tap. We have to open the drainage pathway so things can get out. We have to begin removing very systematically the problem. I've got clients say 10 of them who are taking the exact same parasite protocol for parasites.   Michelle (41:45) Mm -hmm. Yeah. Yeah.   Josh Dech - CHN (42:11) but what they're actually doing is that they're taking them 10 different ways, right? Some of them are tapering in one day on, seven off, one day on, six off, one and five. Some are doing full moon protocol. Some are high dose, some are low. Some are cycling through. Some are consistent dosing. Everyone's different based on their presentations and going the wrong way can make people very, very sick as well. So it's a bit of a tailored and catered process, but the gist would be drainage support.   antiparasitic, supporting what your body lacks or needs, mitochondrial support, so cellular health and cellular well -being, because that's really where drainage and detoxing starts, is at the cellular level, not the macro level so much. And this is sort of a brief overview of that might look like.   Michelle (42:55) So interesting. And another question that I have, a lot of times you'll hear about the keto diet and how I'm not big on fad diets in general, because it's like everything's customized, but you hear about the benefits for some people. The thing with that is that there's barely any fiber. It's really, really low in fiber. So I just wanted to get your take on that.   Josh Dech - CHN (43:05) Sure.   Sure. It was really interesting. Look at someone like Michaela Peterson, right? Does an amazing job with the lion diet, which is basically red meat, salt and water. I am not against it. I think it's a great therapeutic diet. I'm not sold entirely. I've met with some amazing carnivore doctors and specialists, but I will say I don't believe plants are inherently bad for humans. I do believe an animal based diet tends to be better, but the question has to be asked, is it the pesticides and the chemicals on our food that makes plants the problem?   Is it plants themselves? Is it the GMOs and the crops that never existed even 100 or 500 years ago that were not accustomed to eating? The arguments can be made for dairy, where humans have only really domesticated dairy animals for 10 to 15 ,000 years. So are we really adapted to eating dairy? Have we developed or evolved these enzymes and processes to properly assimilate dairy? So the argument about plants versus animal -based   I can put it on a very macro level without getting to the nitty gritty and say this. The bigger fish in the bowl, we talked about prebiotics, they eat fiber, right? The bigger fish in the fish bowl will eat first. If you have an overgrowth of bad bacterium, we'll say, we'll say opportunistic, they're causing you problems and they eat first, they poop out problematic things. So going to the lion diet, you're not gonna get nearly as many microbes eating meat, for example, as they would fibers or starches or sugars. So if you cut those things out right away,   you've reduced the poop or the byproducts, we call them endotoxins of these microbes by simply cutting fiber. And so you may be starving some out, you may be just not getting over gross, you may be no longer contributing to poisons or toxins so much. And there's two arguments to be made. Well, the beef or the animal might filter the toxins. The other argument is what's called bio magnification, which is where it condenses all these toxins in the tissues, which you then consume. But you can't argue with the data, millions of people.   Michelle (44:49) Mm   Mm   Josh Dech - CHN (45:15) all over the world go carnivore or keto and feel better. The question is, do I believe carbs are inherently bad for you? No. Do I believe they should be more sparingly? Yes, just simply biologically. but, but, but this is the big but, we have to understand that your current state of health and how it's utilizing what you're putting into it makes all the difference. You could put gasoline into a car and it's going to drive for miles. You put gasoline into a car that's on fire and it's going to make a bigger fire.   Michelle (45:19) Mm   Mm   Mm -hmm. Yeah.   Josh Dech - CHN (45:45) So it's not the fuel source necessarily that I believe is the problem as much as the body you're putting it into and what's going on on a microbial level.   Michelle (45:51) Yes. that's so important. And I think that, yeah, a lot of what you're saying is so important, but that's really the key crux of it is that your body and your body's condition and your snapshot in time at this moment has unique needs, even unique to five years ago, the same body, which actually it's a different body because the body changes all the time. So it is really important that you work with somebody.   Josh Dech - CHN (46:04) Yeah.   Michelle (46:17) and not do this at home on your own and not self -diagnose because it could be very tempting to do. This is great information, but just hold yourself back from self -diagnosing. Reach out to people like Josh. So actually my next question, if people do want to work with you, how can they reach you? How can they find out more about your work and what you do and get help with their own gut and inflammation?   Josh Dech - CHN (46:19) Yes.   Yeah, I'd love to be able to help Michelle. The quickest way to reach me, you can find everything you need through our website, gutsolution .ca. We got clients in 26 different countries and all the concurrent time zones. So don't worry about where you're located. We can help. That's gutsolution, all singular, .ca for Canada. You can find our podcast, Reversible, where it's about the gut. It's all how all things impact the gut and vice versa. Michelle, we had you record an episode there recently and it's how our gut and our world interact. It's called Reversible.   Reverse Able, the Ultimate Gut Health podcast. And there's also one we released recently about, I'd say six or eight weeks ago, it's called Reversing Crohn's and Colitis Naturally. And it's all about just Crohn's, Colitis and the cruxes and the roots and how we actually get at the root causes of these. But all that can be found, the website, the podcast, contact, help information can all be found at gutsolution .ca.   Michelle (47:37) And how do you work with people?   Josh Dech - CHN (47:38) Yeah, contrary to what most people believe, we don't actually need to see you in person at all. Strictly through symptoms, I get photos if we need them. We'll have you take pictures of your fingernails, pictures of your tongue, for example. It's part of Chinese medicine, as you know, can give us lots of information. We look at blood work. We'll look at your symptoms. We'll look at you as an individual. And we'll spend, I'll spend 30 minutes to an hour on a first call. We get someone through the program and register. There's probably 100, 200 different questions.   Michelle (47:49) Mm   Mm   Josh Dech - CHN (48:08) Extremely thorough intake we do secondary interviews then we do programming and we actually work with you on a weekly basis for 16 weeks very hand -holding process and that's what it looks like because Dealing with bowel disease, know that things can change in an instant You can go from healthy to a flare or healthy to sick to constipation to diarrhea What your doctor does is here's a med see me in three to six months. We'll see how you're doing That doesn't help. You're barely managing and your body can be so finicky   Michelle (48:33) Mm Yeah. Yeah.   Josh Dech - CHN (48:37) And so our job is 16 weeks. And I'll tell you, Michelle, we had a lady recently came out of our program was working not with myself, actually, with Curtis, one of our other specialists. And 16 weeks, she came out after 15 years. She was diagnosed in 2013, a couple of years of bowel disease before that. Her colon was so severe, she described it as squirrels with razor blades running around on her insides. So severe, they were on the cusp of cutting her bowels out. 16 weeks, she came back, her doctors jaw on the floor is like, I've never seen anything like this.   Michelle (48:58) my God, wow. Yeah.   Josh Dech - CHN (49:06) perfect colonoscopy. had one little speck left that we're still obviously going to be fixing, but it took 16 weeks. That's it. And not everybody responds as well. Some respond quicker, but this is what's possible. And I just really want to encourage just if you're listening to this right now, you're like, I've got Crohn's colitis or even severe IBS. I've been told it's genetic autoimmune. There's no known cause. So much can be done. Just start with the website. There's podcasts on there. There's information on that. There's videos on there.   Michelle (49:14) Wow.   Yeah.   Josh Dech - CHN (49:35) There's so much about it that we just want to creak that door open for you and show you what's possible. But again, just head to gut solution .ca and do some diving.   Michelle (49:44) Awesome. Josh, this is amazing. Really, really amazing. And also so important. I can't even stress it enough. I see it a lot even in my patients that come in. and something that I think everybody listening to this, if you're trying to conceive,   you have to go check out Josh and listen to his podcast and learn more because I think it's just so valuable. So thank you so much for coming on today. This is great.   Josh Dech - CHN (50:07) Thank you.   It's been a pleasure, Michelle. And if I could leave one little nugget, if you're considering, if you're trying to conceive or have plans in the future, get ahead of the gut because you can, we talked about great grandma passing down this dysbiosis to you, you can pass down disease to your children. It'll be called genetic. I've seen babies, know, infants. I'm talking a couple of months to two, three years old with bowel disease because we just didn't know ahead of time that we need to be dealing with our gut issues before having children.   because these are the issues we can pass. All those opportunistic microbes, the fungi and parasites, they will come from you to your baby. And this goes both ways. The sperm quality has a lot more to do with it than we used to. We used to say, well, everything's up to mom. It is in development, but even the sperm quality, if mom or dad have gut issues, there's a much higher risk for your baby having some kind of issue down the road. And I just really want to encourage you, if you think there might be gut stuff where you know there's a diagnosis, start there.   long before conception, only will it help in your ability to conceive but to carry a baby to full term and have a healthy baby to give them the best possible future. That's where we start. We have to start in your guts.   Michelle (51:20) So important. Thank you so much, Josh.   Josh Dech - CHN (51:23) A pleasure, Michelle. Thank you for having me.    

In today's episode, we are joined with James and Dahlia Marin, Integrative Registered Dietitians who specialize in SIBO, IBS, SIFO, Histamine intolerance, MCAS and Dysbiosis. They discuss the importance of integrative health practices, the rise of awareness around SIBO (Small Intestinal Bacterial Overgrowth), and the pitfalls of diagnosing and treating gut health issues. The conversation emphasizes the need for lifestyle changes and a deeper understanding of the microbiome to improve overall health. In this conversation, we dive into the complexities of gut health, particularly focusing on SIBO (Small Intestinal Bacterial Overgrowth) and how to support your body through these challenges.Topics of discussion:The importance of proper treatment protocolsWhy the animal based diet will do more harm than goodWhat is SIBO, SIFO, IBS and what they all have in commonThe challenges in diagnosing SIBO, and the significant role of diet and lifestyle in managing gut healthThe impact of the nervous system on digestionThe connection between anxiety and gut healthPractical tools for achieving balance in gut healthInsights on the relationship between food and gut healthWhy "It's not just about what you eat, but the state of your gut health that matters"and more!!Episode sponsor: KIONVisit getkion.com/guttalk for 20% off your order of Kion Aminos and their other high quality products/supplementsFollow Dahlia and James on InstagramMarried to Health WEBSITE

Explore the differences between SIBO (Small Intestinal Bacterial Overgrowth), IMO (Intestinal Methanogen Overgrowth) and hydrogen sulfide SIBO, and dysbiosis, and what makes them different. Dive into their distinct causes and symptoms and what kinds of tests are appropriate in which situations. Lindsey Parsons, your host, helps clients solve gut issues and reverse autoimmune disease naturally. Take her quiz to see which stool or functional medicine test will help you find out what's wrong. She's a Certified Health Coach at High Desert Health in Tucson, Arizona. She coaches clients locally and nationwide. You can also follow Lindsey on Facebook, Tiktok, X, Instagram or Pinterest or reach her via email at lindsey@highdeserthealthcoaching.com to set up your free 30-minute Gut Healing Breakthrough Session. Show Notes

TODAY ON THE ROBERT SCOTT BELL SHOW: Health Freedom Expo Recap, Shemane Nugent, Faith & Freedom, Toxic Mold and Wellness, Aethusa Cynapium, Pfizer's ‘Hot Lots', Vaccine Injury Link, Gut Dysbiosis and Arthritis, Lower Childhood Vaccination Rates, DNA Data Concerns, and MORE! https://robertscottbell.com/health-freedom-expo-recap-shemane-nugent-faith-freedom-toxic-mold-and-wellness-aethusa-cynapium-pfizers-hot-lots-vaccine-injury-link-gut-dysbiosis-and-arthritis-lo/.

In this episode, we talk about a hot topic - the gut microbiome. A lot of information and science is coming out about the impact the gut has on overall health. The gut is the entry point to the body and there are strategies to strengthen the gut which has an impact on health and disease prevention.  This what you'll learn in this episode: Why the gut microbiome should be it's own organ The difference between prebiotics and probiotics Foods to eat that help boost the gut microbiome Here's what's on the menu: [02:02] A breakdown of the gut microbiome [05:20] Foods that help boost the gut microbiome [06:30] What is meant by symbiosis and foods that can disrupt the gut leading to dysbiosis [13:40] What happens when someone has a gut disorder or inflammatory condition that interrupts that function of the gut and how it can be challenging to treat on an individual level [18:20] Why cutting out food groups can have a negative impact on the gut microbiome [19:19] Foods that are considered "prebiotics" and why they help the gut microbiome [20:24] Foods that are considered "probiotics" and how they contribute to a thriving gut microbiome [26:55] Our thoughts about doing a gut detox [33:50] Happy Hour: The impact of a new year If you have a question you want featured om the pod, send us a message on Instagram @WTF_doIEat. And be sure to follow the podcast so you don't miss any new episodes. 

Today I want to talk about another short chain fatty acid booster, which also supports long term gut healing and symptom relief, and that's partially hydrolysed guar gum. PHGG is a soluble fibre derived from the guar bean plant, it is not exactly the same as the food ingredient guar gum. PHGG is broken down by enzymes from guar gum, and dissolves in water. In contrast, guar gum is a thickening agent and too much guar gum in certain foods can cause gut problems, whereas PHGG is recognised as being a supportive, prebiotic fibre and supplement for gut health. Read more. Show notes PHGG and butyrate https://www.mdpi.com/2673-8007/4/2/49 https://www.sciencedirect.com/science/article/abs/pii/S0308814623016242 Bloating, constipation, diarrhoea, IBS and dosing https://pubmed.ncbi.nlm.nih.gov/25843197/ https://www.sciencedirect.com/science/article/abs/pii/S0899900702010328 https://www.monashfodmap.com/blog/fibre-supplements-ibs/ https://figshare.utas.edu.au/articles/conference_contribution/Does_Partially_Hydrolysed_Guar_Gum_HAVE_a_Role_to_Play_in_the_Treatment_of_Irritable_Bowel_Syndrome_A_Systematic_Review/23148182 https://www.sciencedirect.com/science/article/abs/pii/S0899900705003138 Microbiome, PHGG and SCFA https://www.mdpi.com/2072-6643/12/5/1257 https://www.sciencedirect.com/science/article/abs/pii/S0308814623016242 https://pubmed.ncbi.nlm.nih.gov/25519526/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744437/ https://www.elsevier.es/en-revista-annals-hepatology-16-articulo-notable-intestinal-dysbiosis-orchestrated-by-S1665268122001545 https://www.sciencedirect.com/science/article/abs/pii/S0008621519301302 Endo and microbiome alterations https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1363455/full https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1110824/full https://atm.amegroups.org/article/view/54025/html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9729346/ https://www.mdpi.com/1424-8247/16/12/1696 https://link.springer.com/article/10.1007/s00404-024-07631-x SIBO https://pubmed.ncbi.nlm.nih.gov/20937045/ Microbiome tests https://smartnutrition.co.uk/shop/comprehensive-stool-test-gi-map-pathogen-plus-uk-and-europe-igimap/ https://invivohealthcare.com/products/testing/vaginal-ecologix/ (My favourite for UK) https://regeneruslabs.com/products/womens-complete https://www.juno.bio (USA based fav) Free resources: This podcast!  Endometriosis Net Column Endometriosis News Column Newsletter Instagram Email me: hello@theendobellycoach.com Ways to work with me: This EndoLife, It Starts with Breakfast digital cookbook Masterclasses in endo nutrition, surgery prep and recovery and pain relief Live and Thrive with Endo: The Foundations DIY course One to one coaching info and application This episode is sponsored by BeYou Cramp Relief Patches. Soothe period cramps the natural way with these 100% natural and discreet menthol and eucalyptus oil stick on patches. Click here to find out more and to shop: https://beyouonline.co.uk/pages/how-it-works Produced by Chris Robson

In today's episode, we dive into the molecular mechanisms underlying neuroinflammation, with a particular focus on how gut-derived endotoxins, such as lipopolysaccharides (LPS), perturb the blood-brain barrier (BBB) and propagate neuroinflammatory cascades. In more detail, we'll discuss how intestinal dysbiosis and increased intestinal permeability can allow endotoxins such as LPS to enter systemic circulation and cross the blood-brain barrier (BBB), where they activate microglia via the TLR4 signaling pathway. We will explore symptoms including brain fog, memory impairment, mood disturbances, decreased concentration, and cognitive fatigue; as well as tools to support the gut-microbiota-brain axis. Topics: 1. Introduction to Neuroinflammation - Definition and general overview - Key brain cells: neurons, glial cells, and endothelial cells - Chronic neuroinflammation and microglial cells 2. Cellular Mechanisms of Neuroinflammation - Role of microglia in detecting damage or infection - Microglial activation through PRRs/TLRs - Release of pro-inflammatory cytokines and reactive oxygen species (ROS) - Impact on neurons and synaptic plasticity: memory and learning 3. Astrocytes in Neuroinflammation - Astrocytes' contribution to the inflammatory response 4. Chronic Neuroinflammation and Brain Health - Prolonged activation: oxidative stress, excitotoxicity, impaired synaptic function - Impairment of synaptic plasticity and cognitive decline - Mitochondrial dysfunction and cell death cascades - Compromised blood-brain barrier integrity 5. Contributing Factors to Neuroinflammation - Environmental toxins and pollutants, viral or bacterial infections, chronic sleep deprivation, and more 6. Intestinal Dysbiosis and Neuroinflammation - Role of Gram-negative bacteria and LPS (lipopolysaccharides) - Increased intestinal permeability and passage of LPS - LPS transport: transcellular and paracellular pathways - Impact on the blood-brain barrier (BBB) 7. LPS Activation of Microglia - LPS binding to TLR4 on immune cells - Microglial activation and cytokine release - Cognitive impairments and neurodegenerative processes 8. Intestinal Hyperpermeability - Bioindividual approaches: prebiotics, probiotics, polyphenols, bacteriophages - Support for intestinal mucus secretions and sources of mucilage - Butyrate - Glutamine 9. Beneficial Gut Microbiome-Derived Metabolites and Brain Health - Types of metabolites: SCFAs, tryptophan metabolites, polyphenol metabolites - Role of butyrate in crossing the BBB and modulating brain function - Influence on gene expression and synaptic plasticity - Contribution to gut barrier integrity and protection against endotoxins 10. Conclusion - Recap of neuroinflammation's impact on cognitive function + symptoms Thank you to our episode sponsor: 1. Check out ⁠⁠⁠⁠⁠Daily Nouri⁠⁠⁠⁠⁠ and use code ⁠⁠⁠⁠⁠CHLOE20⁠⁠⁠⁠⁠ for 20% off your order. Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠" Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

Naturopathy is a healthcare system that recognises the healing power of nature present in all living things. As a holistic system, it aims to promote and restore health by employing various natural treatment approaches that may include: naturopathic nutrition, lifestyle advice, hydrotherapy, physical therapy, naturopathic psychosocial support and other appropriate techniques. Naturopathic practitioners interpret presenting symptoms as the individual's unique response to physical, emotional, environmental or genetic stress factors which can be identified by examining family medical history and various test results. The practitioner's role is to identify underlying causes and to promote the inherent self-healing power within the individual. Naturopathy is also a way of life and the naturopath will help empower each individual through education about lifestyle, diet and exercise, and self-care. Naturopathic medicine and nutrition provide invaluable methods to identify the root causes of dysfunction in your body, the provision of essential nutrients to support life, and your ability to absorb them. Current research suggests that many of the common and chronic health conditions may be prevented and possibly reversed with a healthy diet and lifestyle, and stress management (e.g., mindfulness, gratefulness and journaling). He discusses diet, nutrition and their relationship with health both physical and mental. Website: www.nutrunity.com Youtube. https://www.youtube.com/@nutrunity Instagram: 116426497_215710006449074_4247510528091082070_n.jpg Twitter. https://x.com/NutrunityUK/ Tik tok. https://www.tiktok.com/@nutrunity.uk Link to his book Energize. https://www.amazon.co.uk/Energise-Vitality-Inflammation-Clarity-resilience/dp/B0B5Y5ZQ4J/ref=sr_1_5?crid=2M45PDPUT1HPE&keywords=energise&qid=1667928475&s=books&sprefix=energis%2Cstripbooks%2C204&sr=1-5

In this solo episode of the Balancing Chaos Podcast, Kelley focuses on the essential role of nutrition in fueling our bodies for long-term health and vitality, moving beyond the short-term goals of weight loss so that you can improve metabolic health for the long run. She emphasizes how diets that focus solely on calories and restriction fail because they eliminate key macronutrient groups or restrict calories too severely -- both of which are vital for metabolic health, hormonal balance, and disease prevention.Kelley highlights the importance of understanding nutrition as a tool for maintaining not just a healthy weight but also for long term health and lifespan; metabolic health is the greatest predictor of chronic disease. By nourishing our bodies with the right balance of nutrients, we can optimize metabolic health, support hormonal balance, and enhance digestive function. Throughout the episode, she answers listener questions on topics such as the critical role of fiber in the diet, why fruit for breakfast alone isn't a good option for weight loss and energy and  what your diet should look like for fertility and pregnancy.Kelley also touches on digestive health and how to use nutrition to improve gut health, which is foundational for immune function, cognition and energy . She provides insights into how to get more fiber into your diet since 90%+ of Americans are not getting enough for detoxification and finally offers her personal recommendations for prenatal vitamins, comparing different supplements to help listeners make informed decisions.This episode is packed with actionable advice and insights on how to nurture your metabolism through proper nutrition so that you can lose weight in a sustainable way AND elongate your lifespan by preventing chronic disease, offering listeners a holistic approach to health that goes far beyond dieting. Tune in to learn how to create sustainable, health-boosting habits that support both weight management and overall well-being.To book a lab review click HERE

I interviewed Symbiosis/Dysbiosis: Sentience co-directors Tosca Terán and Brendan Lehman at Venice Immersive 2024. See more context in the rough transcript below. Here's their artist's statement: https://www.youtube.com/watch?v=0PzZXrqncsY This is a listener-supported podcast through the Voices of VR Patreon. Music: Fatality

Why You Should Listen:  In this episode, you will learn about integrative pediatrics and how to create whole child resilience.    About My Guest: My guest for this episode is Dr. Elisa Song.  Elisa Song, MD is a Stanford, NYU, UCSF-trained integrative pediatrician, pediatric functional medicine expert, and mom to 2 thriving children - and she is on a mission to revolutionize the future of children's health.  Dr. Song is the bestselling author of the "Healthy Kids Happy Kids: An Integrative Pediatrician's Guide to Whole Child Resilience".  Dr. Song created Healthy Kids Happy Kids as an online holistic pediatric resource to help practitioners and parents bridge the gap between conventional and integrative pediatrics with an evidence-based, pediatrician-backed, mom-approved approach.  In her integrative pediatric practice, she's helped 1000s of kids get to the root causes of their health concerns and empowered parents to help their children thrive by integrating conventional pediatrics with functional medicine, homeopathy, acupuncture, herbal medicine, and essential oils.  Dr. Song is chair of A4M's pediatric education and has lectured around the world at leading integrative and functional medicine conferences and premier parenting events.   She has also been featured in hundreds of top podcasts, print and online media outlets, including the Wellness Mama podcast, BloomTV, Forbes, Healthline, MindBodyGreen, National Geographic, PopSugar, Parents, Motherly, Parade, Verywell Health, and New York Post. Key Takeaways: Can Ulcerative Colitis and Crohn's be resolved? What role do environmental toxicants play in children's health? What are the more common patterns of GI dysbiosis? Can the fingerprint of the microbiome paint the diagnosis? When does neurotransmitter testing make sense? How important is exploring SNPs in children? What are some tools to address intestinal hyperpermeability? What is the role of autoimmunity and immune modulation in persistent conditions? What increases and decreases endotoxins or LPS in the body? Is it more important to add more good guys or to reduce the bad guys? Is kombucha a health food? How do artificial food dyes and colorings impact the microbiome? Are all seed oils bad? Which artificial sweeteners support our microbiome and which harm it? How does glyphosate impact health? Is EMF hygiene in the sleep location important? Are prebiotics feeing the bad guys as much as the good guys? What are the best tools for evaluating and treating parasites? Connect With My Guest:  http://HealthyKidsHappyKids.com Related Resources: Book: Healthy Kids, Happy Kids Interview Date: August 1, 2024 Transcript: To review a transcript of this show, visit https://BetterHealthGuy.com/Episode204. Additional Information: To learn more, visit https://BetterHealthGuy.com. Disclaimer:  The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority. 

Herbalist Olivia Amitrano gives us a rundown of the best herbs for treating depression, anxiety, and stress in the gut! What's the right herb for you? Find out now!  Watch Olivia's full interview where she talks all things herbal medicine and how it can heal different conditions: These Natural Herbs Are the SECRET KEY to Better Gut Health | Olivia Amitrano: https://www.youtube.com/watch?v=Q3e2OQHSnns&t=1551s

Continuing our Got Gut Health? Series, today's episode will dive into the topic of gut dysbiosis, the gut microbiome, and issues that arise from gut dysbiosis. Topics include:   - Part 3 of Got Gut Health Series - Gut Health 101 Workshop - Gut Dysbiosis - Gut Microbiome Starts at Birth - What is Bacterial Dysbiosis? - Potential Side Effects - IBS - Autoimmune Diseases - CRONS - Tom Brady's Stool - Causes of Dysbiosis - Share, Rate, and Review ----------  Join Our Gut Health 101: Demystifying Digestive Health Live on July 30th, 2024   ----------     Grab a Copy of My New Book - Metabolism Made Simple     ----------   Stay Connected:     Instagram: @sammillerscience     Youtube: SamMillerScience     Facebook: The Nutrition Coaching Collaborative Community     TikTok: @sammillerscience       ---------- “This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at team@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."  

Wellness + Wisdom | Episode 638 How is Tiny Health helping parents and children optimize their gut health? Cheryl Sew Hoy, Founder of Tiny Health, joins Josh Trent on the Wellness + Wisdom Podcast, episode 638, to explain the correlation between parents' gut microbiome and their baby's gut health, why the first months of a baby's life define their health for the rest of their life, and how microbiome testing can prevent chronic diseases in children. "If your child has poor and imbalanced gut health in the first 6-12 months of life, we can predict if the child is at higher risk for atopic march symptoms; eczema, allergy, and asthma." - Cheryl Sew Hoy $20 Off Tiny Health Tests $20 off with code "JOSH20" Tiny Health is the first gut health test for moms and babies 0-3 years. Detect gut imbalances and course correct early on. Now offering microbiome tests for the whole family! Get to the root cause of chronic conditions: Reduce microbiome risk and relieve eczema, colic, allergies, constipation, and other gut-related issues Recover from antibiotic exposure: Get tailored recommendations to offset the negative impacts of antibiotics Track and optimize your family's health: Test proactively and take action early to support a lifetime of better health Learn the best ways to support the gut: Get the tests, tools, and insights you need to improve wellness over time In This Episode, Cheryl Sew Hoy Uncovers: [01:30] Healing The Baby Microbiome Cheryl Sew Hoy Tiny Health - Use code "JOSH20" for $20 OFF all single kits The different microbiomes in the human body. Why some microbes are beneficial to your health. You get the first microbes from your mother through the vaginal canal and then breast milk. C-section doesn't allow for the baby to acquire certain microbes. How gut microbiome imbalances show up in babies. [08:45] C-Section Affects The Baby's Gut Health The health system is made to make money. How breech birth taught Cheryl to advocate for herself. The impact of C-section birth on the baby's health. How to provide vaginal microbiomes for the baby when a mother gets a C-section. [17:50] Optimizing The Mother's Microbiome A mother should make sure her gut and vaginal microbiomes are healthy before passing them on to her baby. Testing can help you optimize microbiome health. You can take probiotics and pass them on to your baby through breastfeeding. It takes much longer for adults to correct their microbiome. [23:15] The Journey with Tiny Health Why akkermansia is an essential intestinal bacteria. The bacterias that are missing in the mother can be passed on to the baby from the father. Chewing food for your baby can help their microbiome. The infant microbiome development: mom matters How Cheryl developed Tiny Health. [30:15] Nature Heals Your Microbiome Contact with animals makes children's microbiome more diverse. We used to live 90% outdoors, but now we spend 90% of our time indoors.  You can intentionally expose your children to different microbes. How Tiny Health is helping people to go back to nature. [35:05] Asthma Prevention in Infants 236 Healing The Second Brain: Dr. Michael Ruscio Academic research takes 10 years to reach medical practice. How asthma can be prevented by healing the microbiome in early childhood. Why Tiny Health got casted for Shark Tank but decided not to take the opportunity. [39:40] The Gut-Brain Axis Connection Even successful people can be miserable. How stress impacts the gut microbiome. The mother's butyrate function affects her baby's behavior. It has been proven that the gut influences allergies, eczema, and asthma in babies. Why we're in a pediatric chronic condition crisis. [44:00] New Technology for Microbiome Testing Doctors are not taught about the importance of nutrition and the microbiome. How the modern medicine is developing. Why Tiny Health uses metagenomic sequencing to test the microbiome. Each strain of bacteria has a different purpose. 048 Nir Eyal: Breaking Bad Habits, Technology Addiction, & Emotional Triggers [49:15] How to Heal Gut Dysbiosis How Tiny Health achieved to make the test affordable. Everything changes when you have a child. Why Josh's son had gut dysbiosis. The adult gut needs different foods than the baby gut. You should test, not guess when you supplement. What type of probiotics will actually help you improve your gut. How Tiny Health is tracking strains of bacteria. [56:00] Most Supplements Don't Absorb Well 616 Alex Wolfe | Legal Psychedelic Microdosing For Anxiety + How To Take Your Sleep/Psyche to The Next Level Why the body doesn't absorb most oral supplements. Supplementation can get you back to the baseline and a good diet will maintain it. Take your health in your hands. [59:05] Antibiotics VS Gut Health How to restore a baby's microbiome if you had a C-section. The microbes you want to see in your child. Baby can regain the good bacteria within a month of taking probiotics. Most children take antibiotics within the first year of life. Ear infection doesn't need to be treated with antibiotics because it's viral, not bacterial. Understanding what supplements are going to help or hurt your child. Do your own research to advocate for your and your child's health. [01:08:30] Excuses + Fear + Stress Unconscious behavior gives people an excuse to say they don't have time and money. How the medical system is making you react out of fear. Join The Liberated Life Community - LiberatedLife.Me Stress and emotions impact your gut. 581 Healthspan Revolution: Game-Changing Biomarker Blood Testing (SiPhox) | Michael Dubrovsky [01:14:50] Healthy Microbiome = Healthy Lifestyle How Tiny Health mixes the knowledge of academic professionals and holistic practitioners. Why women should start restoring their microbiome before they start trying to get pregnant. A healthy microbiome is a lifestyle, not a one-time thing. Why Cheryl's family's gut health got worse when they moved to Austin. Why people often ask Cheryl about children's eczema and sleep. [01:23:50] Tiny Health for Wellness Why Tiny Health's reports are easy to understand for anyone. How household cleaning products can negatively impact your baby's gut health. Why Cheryl picks a different aspect of wellness to focus on during each season. The social constructs we're facing in the world. 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