Podcast appearances and mentions of easton center

Angela is joined by Dr. Dale Bredesen, who discusses the prevalence of Alzheimer's disease and the difference between Alzheimer's and other forms of dementia. He emphasises the importance of early detection and treatment, as Alzheimer's is a progressive disease that can be present for many years before symptoms appear. Dr. Bredesen explains the four phases of Alzheimer's and the potential for prevention and reversal of cognitive decline through lifestyle interventions.   KEY TAKEAWAYS Alzheimer's disease is a common and devastating form of dementia that affects millions of people worldwide. Alzheimer's is characterized by a progressive decline in cognitive function, including memory loss, difficulty with language and communication, and impaired daily functioning. Early detection and intervention are crucial in managing Alzheimer's disease. The earlier the treatment is initiated, the better the chances of preventing or reversing cognitive decline. Lifestyle factors such as diet, exercise, sleep, stress management, brain training, detoxification, and targeted supplements play a significant role in preventing and managing Alzheimer's disease. Hormone therapy, specifically bioidentical hormone replacement, may be beneficial for women experiencing menopause-related cognitive decline BEST MOMENTS "Your generation is the first generation that does not have to fear Alzheimer's." "We can pretty much prevent it or do early reversals in just about everyone." "We do see people even in late stages where we get some improvement, but they don't tend to come all the way back to normal." "Sleep is one of the ways that you stay sharp, that you improve your processing speed." VALUABLE RESOURCES Get a free snapshot of your health and personalised report at www.yourtotalhealthcheck.com Join The High Performance Health CommunityFree Fasting Guide - www.angelafosterperformance.com/fastingPodcast Shownotes - www.angelafosterperformance.com/podcasts Episode 212 - https://omny.fm/shows/high-performance-health/the-science-of-manifestation-how-to-use-neuroplast ABOUT THE GUEST Dale Bredesen, MD, received his undergraduate degree from Caltech and his medical degree from Duke University. He served as resident and chief resident in neurology at the University of California, San Francisco (UCSF) and as postdoctoral fellow in the laboratory of Nobel Laureate Professor Stanley Prusiner. He was a faculty member at UCLA from 1989 to 1994 and was then recruited by the Burnham Institute to direct the Program on Aging. In 1998, he became the founding president and CEO of the Buck Institute for Research on Aging and adjunct professor at UCSF. In 2013, he returned to the University of California, Los Angeles (UCLA) as director of the Easton Center for Alzheimer's Disease Research and he is currently a professor. The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process and the translation of this knowledge into effective therapeutics for Alzheimer's disease and other neurodegenerative conditions, which has led to the publication of over 200 research papers. He is the principal investigator for the Alzheimer's Disease Research Center at UCLA. He established the ADDN (Alzheimer's Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer's disease. His group has developed a new approach to the treatment of Alzheimer's disease, the MEND protocol, and this approach has led to the first description of a reversal of symptoms in patients with mild cognitive impairment (MCI) and early Alzheimer's disease. Dr. Bredesen is the author oftwo New York Times best sellers: The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Declineand The End of Alzheimer's Program. ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. Angela's BioSyncing®️ Blueprint is currently closed. Click here to get on the waitlist. The High Performance Health Podcast is a top rated global podcast. Each week, Angela brings you a new insight, biohack or high performance habit to help you unlock optimal health, longevity and higher performance. Hit the follow button to make sure you get notified each time Angela releases a new episode. CONTACT DETAILS Instagram Facebook LinkedIn

We don't have to fear Alzheimer's and cognitive decline like generations before us. Thanks to dedicated researchers and doctors like today's guest, we know why Alzheimer's happens – and how to prevent it.Dr. Dale Bredesen received his undergraduate degree from Caltech and his medical degree from Duke University. In 2013, he returned to UCLA as the director of the Easton Center for Alzheimer's Disease Research. The Bredesen Laboratory studies the basic mechanisms underlying the neurodegenerative process and the translation of the knowledge into effective therapies for Alzheimer's disease. He has published over 230 papers and has written two New York Times bestselling books, The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline, and The End Of Alzheimer's Program. In today's episode, he fills us in on everything he knows about how to protect your brain from this disease, what Alzheimer's is, how we can reverse and prevent it, and blood tests that can indicate our odds of getting it. Dr. Bredesen is a beacon of hope for so many of us and for families that have been affected by this disease. Knowing that we have the tests to catch early signs of cognitive decline and can harness the power of the Bredesen Protocol to fight inflammation through diet and lifestyle changes in our earlier years means that we can end Alzheimer's.We also cover…(00:01:53) Preventing Alzheimer's(00:06:56) The 4 Stages of Alzheimer's(00:16:12) Understanding the Root Cause of Alzheimer's(00:22:40) Alzheimer's Testing 101(00:25:52) Addressing the Glucose Energetic Emergency(00:30:48) The Bredesen Protocol: Diet Recommendations To Prevent Alzheimer's(00:38:36) What Leads to Brain Inflammation & How To Identify It(00:47:12) Why Alzheimer's Is a Women Centric Disease(00:50:22) Best-in-Class Methods for Reducing Brain InflammationThis episode is brought to you by:BWBK Protein Powder | Get $10 off your order with PODCAST10 at bewellbykelly.com.Cozy Earth | Get 35% off site wide when you use the code BEWELL at CozyEarth.com.MasterClass | This holiday season, give one annual membership and get one free at masterclass.com/bewell. Resources:Click here for full show notesRead: The End of Alzheimer's by Dr. Dale BredesenRead: The End of Alzheimer's Program by Dr. Dale BredesenWebsite:

This episode is truly a thought-provoking conversation about Alzheimer's and its unique impact on women with none other than the legendary Dr. Dale Bredesen (who is making his fourth appearance on the show). Dale Bredesen, MD, received his undergraduate degree from Caltech and his medical degree from Duke University. He served as resident and chief resident in neurology at the University of California, San Francisco (UCSF) and as postdoctoral fellow in the laboratory of Nobel Laureate Professor Stanley Prusiner. He was a faculty member at UCLA from 1989 to 1994 and was then recruited by the Burnham Institute to direct the Program on Aging. In 1998, he became the founding president and CEO of the Buck Institute for Research on Aging and adjunct professor at UCSF. In 2013, he returned to the University of California, Los Angeles (UCLA) as director of the Easton Center for Alzheimer's Disease Research and he is currently a professor.Dr. Stephanie and Dr. Bredesen delve into the fascinating topic of Alzheimer's as a preventable condition, emphasizing that this is the first generation with the power to make Alzheimer's truly optional. They explore the shift in the common presentation of Alzheimer's, particularly in women, highlighting the rise of subjective or mild cognitive impairment in 52-year-old women.As always, Dr. Stephanie and Dr. Bredesen provide actionable solutions for preventing and managing Alzheimer's, covering diet, exercise, sleep, supplementation, and testing. They introduce innovative blood tests, discuss the importance of a "cognoscopy," and even touch on dental health's role in brain health.Resources Mentioned:Reversal of Cognitive Decline: 100 Patients - https://www.omicsonline.org/open-access/reversal-of-cognitive-decline-100-patients-2161-0460-1000450-105387.htmlTranscriptional Effects of ApoE4: Relevance to Alzheimer's Disease - Transcriptional Effects of ApoE4: Relevance to Alzheimer's DiseaseReCODE: A Personalized, Targeted, Multi-Factorial Therapeutic Program for Reversal of Cognitive Decline. - https://pubmed.ncbi.nlm.nih.gov/34680464/Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism? - https://pubmed.ncbi.nlm.nih.gov/36774227/Reversal of cognitive decline: a novel therapeutic program - https://pubmed.ncbi.nlm.nih.gov/25324467/Reversing the effects of Alzheimer's Disease: Dr. Ron Geyer on NeuroEPO - https://medicine.usask.ca/news/2023/reversing-the-effects-of-alzheimers-disease-dr.-ron-geyer-on-neuroepo.phpDr. Bredesen's TedX talk - https://youtu.be/TzJSCttlQmc?si=sEC_psvctDR0XRkzDr. Bredesen's books - https://www.apollohealthco.com/books/KetoFLEX 12/3™ - https://ketoflex.apollohealthco.comEvanthea Dementia Reversal Trial - https://www.dementiareversaltrial.comInstagram - https://www.instagram.com/drdalebredesen/Episode Overview:0:00:00 Introduction0:05:42 Welcome to Dr. Dale Bredesen0:11:59 Factors driving the shift in Alzheimer's disease onset age0:15:41 COVID-19 and Alzheimer's disease risk0:21:28 The importance of addressing chronic conditions0:24:01 The role of metabolic health in cognitive decline0:25:40 The role of diet in Alzheimer's disease0:26:54 The postmenopausal women and cognitive decline0:35:05 Alzheimer's disease and genetic factors0:36:53 How we could confuse perimenopause with Alzheimer's0:44:39 ApoE4 and the evolution of hominids0:47:42 ApoE4 and its pro-inflammatory effect0:51:23 The limitations of targeting neurofibrillary tangles and plaques0:54:23 Evaluating the efficacy of drugs for Alzheimer's treatment1:04:39 Exploring the use of supplementation in the trial1:05:45 The seven fundamentals for maintain good brain health1:13:57 Importance of sleep hygiene and nasal breathing1:18:38 Tailoring sleep habits to circadian rhythms and environmental factorsWe'd like to thank our sponsors:Go to neurohacker.com/better to try Qualia Senolytic with a 100 day money back guarantee, and code BETTER will get you 15% off your order.Right now Levels is offering you an additional two free months off of the levels annual membership when you use the link levels.link/better.If you want to try Beam Minerals for yourself, head over to beamminerals.com/better for 20% off of the entire store.

Dr Dale Bredesen has demonstrated that we have entered into the new era of Alzheimer's care, and that we are already amongst the horrible disease's first survivors. He makes an incredibly bold statement that getting Alzheimer's disease is “truly optional”. Wow! What an incredible message of self-empowerment and hope. We need this episode more than ever to provide the increasing number of people and their families impacted by Alzheimer's hope and that they can get their mind back and therefore their life back.Dale E. Bredesen, MD, received his undergraduate degree from Caltech and his medical degree from Duke University. He served as resident and chief resident in neurology at the University of California, San Francisco (UCSF) and as postdoctoral fellow in the laboratory of Nobel Laureate Professor Stanley Prusiner. He was a faculty member at UCLA from 1989 to 1994, and was then recruited by the Burnham Institute to direct the Program on Aging. In 1998, he became the founding president and CEO of the Buck Institute for Research on Aging and adjunct professor at UCSF. In 2013, he returned to the University of California, Los Angeles (UCLA) as director of the Easton Center for Alzheimer's Disease Research.The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process and the translation of this knowledge into effective therapeutics for Alzheimer's disease and other neurodegenerative conditions, which has led to the publication of over 200 research papers. He is the principal investigator for the Alzheimer's Disease Research Center at UCLA. He established the ADDN (Alzheimer's Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer's disease. His group has developed a new approach to the treatment of Alzheimer's disease, the MEND protocol, and this approach has led to the first description of a reversal of symptoms in patients with mild cognitive impairment (MCI) and early Alzheimer's disease.Join us as we explore:The forefront of both Alzheimer's disease research and treatment, and why most neurologists are stuck in the past and ineffective treatment, including stories from Dr Bredeson's new book detailing how his approach has already reversed Alzheimer's disease in his patients.The 7 fundamental pieces of Alzheimer's prevention and treatment, including treating the vicious prionic loop.Why everyone over 40 needs to do a “cognoscopy”, and don't worry it's a lot more pleasant than a colonoscopy! Dr Bredeson's research and experimentally backed theory that neurodegenerative diseases are about a gap between supply and demand in your brain's network capabilities, and if you can't reduce the demand how you can increase your brain supply, and how his approach treats the disease at the root which is NOT in the brain itself.The critically important message of hope that even though your biological systems may get dysfunctional over time, they are incredibly resilient and able to reverse themselves to good health if we implement the fundamental basics of functional and natSupport the showSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/

Most everyone knows of a cancer survivor. But, by and large, when a person receives a diagnosis of Alzheimer's disease, it is often assumed that this is an indication of an almost certain outcome.   Alzheimer's disease is not caused by a specific flaw. While energy deficiency, inflammation, infectious agents, beta amyloid, acetylcholine deficiency, trauma, toxins, metabolic issues, and genetics are all worthy of consideration, it is clearly myopic to consider that targeting one of these popular ideas is going to solve the problem. It doesn't.   Our guest today has taken a different approach. Rather than trying to find a unique drug or technique that can help the Alzheimer's population at large, this novel approach focuses on identifying how variations in multiple parameters can be targeted with the overall goal of improving brain functionality that is compromised in the developing Alzheimer's situation. This approach, a personalized medicine approach, directly challenges the notion of a one-size-fits-all mentality as it relates to treating medical problems. And to be sure, Dr. Bredesen is demonstrating incredible success not just in stabilizing Alzheimer's patients but actually in bringing about their improvement. This is revolutionary, and I urge you to pay close attention to his message today.   Dr. Bredesen received his undergraduate degree from Caltech and his medical degree from Duke. He served as Resident and Chief Resident in Neurology at UCSF, then was postdoctoral fellow in the laboratory of Nobel laureate Prof. Stanley Prusiner. He was a faculty member at UCLA from 1989-1994, then was recruited by the Burnham Institute to direct the Program on Aging. In 1998 he became the Founding President and CEO of the Buck Institute for Research on Aging, and Adjunct Professor at UCSF; then in 2013 he returned to UCLA as the Director of the Easton Center for Alzheimer's Disease Research. The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer's disease and other neurodegenerative conditions, leading to the publication of over 220 research papers. He established the ADDN (Alzheimer's Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer's disease. He and his group developed a new approach to the treatment of Alzheimer's disease, and this approach led to the discovery of subtypes of Alzheimer's disease, followed by the first description of reversal of symptoms in patients with MCI and Alzheimer's disease, with the ReCODE (reversal of cognitive decline) protocol, published in 2014, 2016, and 2018. Dr. Bredesen is the author of the New York Times bestseller, The End of Alzheimer's, and the newly released, The End of Alzheimer's Program. His newest book, The First Survivors of Alzheimer's, chronicles how this program has virtually rewritten the lives of so many, and reveals, from the patient's perspective, what this has meant. Here's a link to his latest research paper showing improvement in an astounding 80% of Alzheimer's patients.

Elle Russ chats with Dr. Dale Bredesen, MD - he received his undergraduate degree from Caltech and his medical degree from Duke.  He served as Resident and Chief Resident in Neurology at UCSF, then was postdoctoral fellow in the laboratory of Nobel laureate Prof. Stanley Prusiner.  He was a faculty member at UCLA from 1989-1994, then was recruited by the Burnham Institute to direct the Program on Aging.  In 1998 he became the Founding President and CEO of the Buck Institute for Research on Aging, and Adjunct Professor at UCSF; then in 2013 he returned to UCLA as the Director of the Easton Center for Alzheimer’s Disease Research. The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer’s disease and other neurodegenerative conditions, leading to the publication of over 220 research papers. He established the ADDN (Alzheimer’s Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer’s disease.  He and his group developed a new approach to the treatment of Alzheimer’s disease, and this approach led to the discovery of subtypes of Alzheimer’s disease, followed by the first description of reversal of symptoms in patients with MCI and Alzheimer’s disease, with the ReCODE (reversal of cognitive decline) protocol, published in 2014, 2016, and 2018.  Dr. Bredesen is the author of the New York Times best seller, The End of Alzheimer’s, and the newly released, The End of Alzheimer’s Program.

Alzheimer's Disease is a leading degenerative disease in our older population, but it's one that you can prevent and even treat with early diagnosis. I'm joined by Dale E. Bredesen, MD, to talk about his tremendous work with Alzheimer's patients. Key Takeaways Minor oral concerns that can contribute to Alzheimer's Disease Root canals Mercury Periodontitis Gingivitis Leaky Gums About Dale E. Bredesen, MD Dr. Bredesen received his undergraduate degree from Caltech and his medical degree from Duke. He served as Resident and Chief Resident in Neurology at UCSF, then was a postdoctoral fellow in the laboratory of Nobel laureate Prof. Stanley Prusiner. He was a faculty member at UCLA from 1989-1994, then joined the Burnham Institute to direct the Program on Aging.  In 1998 he became the Founding President and CEO of the Buck Institute for Research on Aging, and Adjunct Professor at UCSF; then in 2013 he returned to UCLA as the Director of the Easton Center for Alzheimer's Disease Research. The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer's disease and other neurodegenerative conditions, leading to the publication of over 220 research papers.  He established the ADDN (Alzheimer's Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer's disease. He and his group developed a new approach to the treatment of Alzheimer's disease, and this approach led to the discovery of subtypes of Alzheimer's disease, followed by the first description of the reversal of symptoms in patients with MCI and Alzheimer's disease, with the ReCODE (reversal of cognitive decline) protocol, published in 2014, 2016, and 2018.  His book, The End of Alzheimer's, was on the New York Times Bestsellers List for 5 months and is available in 32 different languages. Diagnosing Alzheimer's Disease Dr. Dale E. Bredesen joins me to talk about Alzheimer's treatment, prevention, and causes. This is an enlightening conversation and one that so many of my listeners and clients have asked for. This is especially relevant for women, as statistically speaking, we're more likely to develop brain and memory-related diseases as we age. Dale provides us with some insight into why we should focus on our brain health once we turn 35. It's never too early to prepare our bodies for healthy aging. And if you're already showing signs of memory loss, Dale wholeheartedly encourages you to seek medical intervention early. This is one of the reasons it takes so long for an Alzheimer's Disease diagnosis. Because we tend to shrug off minor memory failure as just being forgetful, relying more on our long-term memory, it can be difficult to pinpoint the onset of the disease. Dale also explains how some of the different subsets of Alzheimer's Disease present and what the treatment for these should be. The Keto Diet for Alzheimer's Prevention The first step to treating and preventing Alzheimer's Disease, of course, starts in the gut. Dale recommends a Ketogenic diet that relies heavily on plant-based foods - much like my KetoGreen program. There are so many different approaches to Keto you can take, especially depending on what type of Alzheimer's subset you have. But overall, Dale recommends an overnight fast, vegetable-based, and low in fats such as bacon. Dale also encourages a low Glycemic diet. This is one that's low in sugar, even those occurring in fruits, as so many of our fruits have been genetically modified over the years to have a much higher sugar count than what's natural. Finally, Dale gives some very valuable insight into the importance of our oral health. In fact, some of our more common dental concerns, such as gingivitis and root canals, can directly contribute to your likelihood of developing Alzheimer's Disease! Have you started including a fast in your diet? How long do you fast for? What's your favorite way to break your fast? As always, you can ask me anything and let me hear your thoughts in the comments on the episode page. If you have questions, email team@drannacabeca.com. In This Episode Why women are more at risk of developing Alzheimer's Disease than men are [12:45] What you can do improve your brain health after 35 [18:00] Why you should stay on top of your brain health and function, especially if you have what you think is a minor problem [27:00] Why Alzheimer's Disease takes so long to diagnose [30:30] What kind of approach you should take to the Ketogenic diet [45:00] Quotes “This is a critical piece. You need to make sure for each person that they are getting the appropriate nutrients, blood flow, oxygenation, and hormones to the entire brain.” [19:00] “Your brain has collected so many important memories that this is one of the reasons why Alzheimer's takes so long to diagnose. You can function so well with what you've already learned that the first thing that's sacrificed, as you're now downsizing, is the ability to learn to new things.” [30:26] “The paradox is that we are constructed to eat fruits. But the problem is all the fruits that we're exposed to are extremely high in sugar because people want to sell fruit, they want to make money. They've bred these fruits to be higher in sugar. The paradox is that we're here on Earth to eat fruits, but not to eat the fruits that are currently on Earth.” [1:01:03] Resources Mentioned Know Your Risk for Cognitive Decline with Cognoscopy Find Out More About Apollo Health Check out Episode 42: Food As Medicine To Help Anxiety w/ Ali Miller Find Dale E. Bredesen, MD Online Follow Dale E. Bredesen, MD on Facebook | Twitter | LinkedIn  Join the KetoGreen Community on Facebook Buy Keto-Green 16 Check out the full episode page Find Dr. Anna Online Follow Dr. Anna on Facebook | Instagram | Twitter Related Episodes: 107: What You Need To Do To Help Prevent Alzheimer's Disease w/ Dr. Lisa Mosconi  147: How Ketosis Can Help Heal Your Body w/ Ali Miller, RD 148: Healing Your Gut Issues With Enzymes w/ Steven Wright

Alzheimer’s Disease is a leading degenerative disease in our older population, but it’s one that you can prevent and even treat with early diagnosis. I’m joined by Dale E. Bredesen, MD, to talk about his tremendous work with Alzheimer’s patients. Key Takeaways Minor oral concerns that can contribute to Alzheimer’s Disease Root canals Mercury Periodontitis Gingivitis Leaky Gums About Dale E. Bredesen, MD Dr. Bredesen received his undergraduate degree from Caltech and his medical degree from Duke. He served as Resident and Chief Resident in Neurology at UCSF, then was a postdoctoral fellow in the laboratory of Nobel laureate Prof. Stanley Prusiner. He was a faculty member at UCLA from 1989-1994, then joined the Burnham Institute to direct the Program on Aging.  In 1998 he became the Founding President and CEO of the Buck Institute for Research on Aging, and Adjunct Professor at UCSF; then in 2013 he returned to UCLA as the Director of the Easton Center for Alzheimer’s Disease Research. The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer’s disease and other neurodegenerative conditions, leading to the publication of over 220 research papers.  He established the ADDN (Alzheimer’s Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer’s disease. He and his group developed a new approach to the treatment of Alzheimer’s disease, and this approach led to the discovery of subtypes of Alzheimer’s disease, followed by the first description of the reversal of symptoms in patients with MCI and Alzheimer’s disease, with the ReCODE (reversal of cognitive decline) protocol, published in 2014, 2016, and 2018.  His book, The End of Alzheimer’s, was on the New York Times Bestsellers List for 5 months and is available in 32 different languages. Diagnosing Alzheimer’s Disease Dr. Dale E. Bredesen joins me to talk about Alzheimer’s treatment, prevention, and causes. This is an enlightening conversation and one that so many of my listeners and clients have asked for. This is especially relevant for women, as statistically speaking, we’re more likely to develop brain and memory-related diseases as we age. Dale provides us with some insight into why we should focus on our brain health once we turn 35. It’s never too early to prepare our bodies for healthy aging. And if you’re already showing signs of memory loss, Dale wholeheartedly encourages you to seek medical intervention early. This is one of the reasons it takes so long for an Alzheimer’s Disease diagnosis. Because we tend to shrug off minor memory failure as just being forgetful, relying more on our long-term memory, it can be difficult to pinpoint the onset of the disease. Dale also explains how some of the different subsets of Alzheimer’s Disease present and what the treatment for these should be. The Keto Diet for Alzheimer’s Prevention The first step to treating and preventing Alzheimer’s Disease, of course, starts in the gut. Dale recommends a Ketogenic diet that relies heavily on plant-based foods - much like my KetoGreen program. There are so many different approaches to Keto you can take, especially depending on what type of Alzheimer’s subset you have. But overall, Dale recommends an overnight fast, vegetable-based, and low in fats such as bacon. Dale also encourages a low Glycemic diet. This is one that’s low in sugar, even those occurring in fruits, as so many of our fruits have been genetically modified over the years to have a much higher sugar count than what’s natural. Finally, Dale gives some very valuable insight into the importance of our oral health. In fact, some of our more common dental concerns, such as gingivitis and root canals, can directly contribute to your likelihood of developing Alzheimer’s Disease! Have you started including a fast in your diet? How long do you fast for? What’s your favorite way to break your fast? As always, you can ask me anything and let me hear your thoughts in the comments on the episode page. If you have questions, email team@drannacabeca.com.   In This Episode Why women are more at risk of developing Alzheimer’s Disease than men are [12:45] What you can do improve your brain health after 35 [18:00] Why you should stay on top of your brain health and function, especially if you have what you think is a minor problem [27:00] Why Alzheimer’s Disease takes so long to diagnose [30:30] What kind of approach you should take to the Ketogenic diet [45:00]   Quotes “This is a critical piece. You need to make sure for each person that they are getting the appropriate nutrients, blood flow, oxygenation, and hormones to the entire brain.” [19:00] “Your brain has collected so many important memories that this is one of the reasons why Alzheimer’s takes so long to diagnose. You can function so well with what you’ve already learned that the first thing that’s sacrificed, as you’re now downsizing, is the ability to learn to new things.” [30:26] “The paradox is that we are constructed to eat fruits. But the problem is all the fruits that we’re exposed to are extremely high in sugar because people want to sell fruit, they want to make money. They’ve bred these fruits to be higher in sugar. The paradox is that we’re here on Earth to eat fruits, but not to eat the fruits that are currently on Earth.” [1:01:03]   Resources Mentioned Know Your Risk for Cognitive Decline with Cognoscopy Find Out More About Apollo Health Check out Episode 42: Food As Medicine To Help Anxiety w/ Ali Miller Find Dale E. Bredesen, MD Online Follow Dale E. Bredesen, MD on Facebook | Twitter | LinkedIn  Join the KetoGreen Community on Facebook Buy Keto-Green 16 Check out the full episode page Find Dr. Anna Online Follow Dr. Anna on Facebook | Instagram | Twitter   Related Episodes: 107: What You Need To Do To Help Prevent Alzheimer’s Disease w/ Dr. Lisa Mosconi  147: How Ketosis Can Help Heal Your Body w/ Ali Miller, RD 148: Healing Your Gut Issues With Enzymes w/ Steven Wright

This is an interview I’ve been looking forward to for years. Dr. Dale Bredesen is shaking up the medical world by showing that Alzheimer’s actually can be prevented, treated, and sometimes even reversed. This is really important to me because my mom is the final stages of Alzherimer’s and I, of course, am doing everything I can to prevent myself from falling to the same fate. I believe the Sapien way of eating and lifestyle is doing just that - setting me up for my best chances at my longest healthspan. You can learn more about this at http://sapien.org/diet Dr. Bredesen and I agree on all the core principles. He really is describing a Sapien diet with his protocol. We’re only at odds with the ratio of plant foods to animal foods. As I’ve posted today on social media, I think people are actually more on the side of animal foods than they think. In the context of a whole foods, low carb diet without refined grains, sugar or vegetable oil, more often than not people are getting the majority of their calories from animal foods without necessarily realizing it. Only people eating Standard American Diets or Mediterranean Diets and the like are getting most of their calories from plant foods from all the empty calories coming from grains and other carbohydrates. Many health figures in this space say things like “a plant heavy diet” or “fill half your plate up with greens” and people take this as being akin to a vegetarian diet. As I showed in my post, a daily intake where about 70% of the plates are filled with plants are actually 92% animal foods by calories. I actually eat this way a lot. This is carnivore adjacent and is part of the Sapien Framework. You’re still getting a ton of flavor, variety, and nutrients from plants (even though they’re not as bioavailable), but you're really getting 90% of your calories from animal foods. So make your own decision on the ratio of plant to animal foods, but from what I’ve found, higher animal foods is more species appropriate for homo sapiens, and is actually what most people avoiding empty calorie, nutrient poor foods are already doing. As always, I didn’t want to press him on this. I don’t invite people on my podcast to tell them I don’t agree with their opinions. I’d love for this to be debated with a moderator at some point, but as long as it’s a 1 on 1 Peak Human podcast I’m letting the guest speak their minds. Here’s a bit of Dr. Bredesen’s extensive resume. He received his undergraduate degree from Caltech and his medical degree from Duke. He served as Resident and Chief Resident in Neurology at UCSF, he was the Director of the Easton Center for Alzheimer’s Disease Research, he’s a Professor in the Department of Molecular and Medical Pharmacology at UCLA School of Medicine, and the Founder of the Buck Institute for Research on Aging. The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer’s disease and other neurodegenerative conditions, leading to the publication of over 220 research papers. He and his group developed a new approach to the treatment of Alzheimer’s disease, and this approach led to the discovery of subtypes of the disease, followed by the first description of reversal of symptoms in patients with MCI and Alzheimer’s disease, with the ReCODE protocol, published in 2014, 2016, and 2018. His book, The End of Alzheimer’s, is a New York Times Bestseller and has been translated into 29 languages.   I’ll largely skip the plugs for today. Everyone listening knows about the Food Lies film on Indiegogo, the Patreon at http://patreon.com/peakhuman and my new grass fed meat company http://NoseToTail.org If you find any value in this podcast or my other content on YouTube or social media channels, please consider supporting me and my projects there. I wish I could really get across how much it means to me. It’s honestly the only way any of this is possible. Thanks so much, and I’ll most likely end season 3 with this episode and come back in a couple  weeks with an amazing season 4. Here’s the future legend, Dr. Dale Bredesen. BUY THE MEAT NosetoTail.org Preorder Food Lies: http://indiegogo.com/projects/food-lies-post Support me on Patreon! http://patreon.com/peakhuman   SHOW NOTES   Dr. Bredesen has been studying the phenomenon of Alzheimer’s Disease (AD) for 3 decades and have published over 200 papers on his research Understanding the fundamental nature of the disease is how we can design an effective treatment His protocol is different because it targets the root cause, not the symptoms like most AD drugs do Humans are extremely complicated and there is no one single therapy that will treat the complexity of AD AD is the result of the brain protecting itself from different insults The protective response in the brain causes the brain to shrink and “retreat” so that there is less for foreign substances (insults) to target Amyloids are antimicrobial, bind to toxins, and change the brain’s response to glucose but when they are overproduced and build up that’s when problems occur Some of the contributors to AD are: chronic inflammation, insulin resistance, glycation damage, toxin exposure, decrease in nutrients, hormones, trophic factors, poor vascular support He has identified and categorized 6 different types of AD: inflammatory, atrophic, glycotoxic, toxic, vascular, and traumatic Paraffin candles produce toxins that damage the brain Most damaging mycotoxins (produced from mold) are the ones you breathe - test your home for molds Go to www.survivingmold.com to learn how to test your home for mold and if you are concerned about mold exposure to learn about what to personally get tested For overall markers you should get tested, you can order tests directly from Dr. Bredesen’s site www.drbredesen.com or go to your doctor and test markers Markers for glycotoxicity: fasted insulin, HbA1c, and fasted glucose Markers for nutrients, hormones, and trophic factors: o   Vit. D, pragnenolone, progesterone, estradiol, testosterone, free T3 and free T4 (for thyroid), TSH (thyroid stimulating hormone), and reverse T3 (which is an inhibitor of the effect of your active thyroid hormone) Inflammation markers: HS-CRP, TNF-a, IL6, IL8, IL1-b Don’t wait until it’s too late to check for these things, because AD is preventable Glycotoxicity and how sugar is toxic Humans are not designed to eat sugar Overconsumption of sugar is linked to hypertension, CVD, diabetes, dementia, arthritic, leaky gut, and more Sugar is this generation’s smoking, we will get to a day when we think back to how crazy it was that we were eating this stuff We have biomarkers that will tell you whether AD is creeping up on you, so check early in life because you might not feel sick now, but that doesn’t mean it’s not on its way All these lifestyle and diet changes that you make to prevent AD, apply to so many other modern illnesses If AD runs in your family, you should be interested in prevention AD should be a rare disease APOE4 is the most common genetic risk factor If you have a single copy of APOE4 the risk is ~30% If you have a double copy of APOE4 the risk becomes greater than 50% For people with APOE4, find out early and get on prevention, and you will have a low chance of getting the disease 21st century medicine is about root cause and prevention There is no mono-therapy for AD Look out for symptoms of early cognitive decline like the lack of ability to learn new things, losing organizational skills, not being able to do simple calculations, not being able to find the right word, getting lost in familiar places Don’t shake these off as “senior moments” Basic things everyone can do: optimize insulin sensitivity, follow a low-carb, moderate protein, high (good) fat diet, exercise, get enough sleep, reduce stressors in your life, detox, avoid or fix any gut issues, go into periods of ketosis His diet plan is called “KetoFlex 12/3” “Keto” for going into periods of ketosis “Flex” because it is flexitarian, if you want to be a vegetarian or eat meat you can do either “12” because he wants people fasting for at least 12 hours between dinner and the next day’s first meal “3” because he wants people to finish eating at least 3 hours before they go to sleep The Big Four to avoid: grains, simple carbs, dairy, and lectins He has had amazing success with his patients and has been publishing results since 2014 He has never had someone at risk come in for prevention and develop even mild cognitive impairment (MCI) People who come in with subjected cognitive impairment (SCI) see improvement People who come in with MCI the majority improve People with full-blown AD, some people improve and some people don’t He has had people score zero on cognitive tests that have improved The most important point of all of this is that if you get put on a drug for AD you might get a little bump but you fall back to declining again, his approach targets what is actually causing the decline, the people who get better sustain their improvement Complexity gap between the complexity of the problem (human illness) and the data sets that traditional medical doctors are using to treat them (aka we can’t expect a simple mono-therapy to treat a complex condition) Dr. Bredesen’s daughter is a brain health coach and you can find her at www.siabrainhealth.com His protocol includes sauna for riding the body of toxins We are swimming in an Alzheimer’s soup with the amount of toxins we are exposed to in our modern world Get rid of toxins by sweating (sauna and exercise), high fiber diet, optimizing glutathione levels, filtered water, urination, each one of these gets rid of different things If you have leaky gut, fix that The importance of sleep Current research on macular degeneration His new book coming out “The First Survivors of Alzheimer’s Disease” will be about people’s first-hand stories of people told they had no hope but used his protocol and got better and have kept themselves better The future of medicine will need to look at how humans were evolutionarily designed to live You are not powerless to AD, you have control over it We can reduce the global burden of dementia, we can fight cognitive decline Find Dr. Dale Bredesen at www.drbredesen.com His Facebook page https://facebook.com/drdalebredesen/   BUY THE MEAT NosetoTail.org Support me on Patreon! http://patreon.com/peakhuman Preorder the film here: http://indiegogo.com/projects/food-lies-post   Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Sapien Movement: http://SapienMovement.com   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg   Theme music by https://kylewardmusic.com/

This is the second part of our interview with Monica R. Moore, MSG, and Dr Sarah Kremen, MD, of the Mary S. Easton Center for Alzheimer's Disease Research at UCLA. In this episode, Dr. Kremen discusses the work of the Easton Center in conducting clinical trials and Alzheimer's Disease research.

This is the first segment of a two-part interview with Monica R Moore, MSG, and Dr. Sarah Kremen MD. We discuss their incredibly important work within the field of Alzheimer's research, education, and resource provision at the Mary S. Easton Center for Alzheimer's Disease Research at UCLA. 

Mark and Dr. Gladden invite Dr. Dale Bredesen on the podcast to speak about the science of cognitive decline and its prevention. Dr. Bredesen is an expert on neurodegenerative diseases, and he discusses multiple risk factors for Alzheimer’s and dementia, including those both genetic and environmental. They examine crucial things you should do in your routine and environment to help reduce the risks that contribute to cognitive decline. Mark and Dr. Gladden review a number of advances in longevity research, considering the impact they might have on improved cognitive function.  About the guest: Dale E. Bredesen, M.D., UCLA and Buck Institute Professor, Department of Molecular and Medical Pharmacology David Geffen School of Medicine at UCLA, Los Angeles, CA Founding President and CEO, Professor Emeritus, Buck Institute for Research on Aging, Novato, CA Dr. Bredesen received his undergraduate degree from Caltech and his medical degree from Duke.  He served as Resident and Chief Resident in Neurology at UCSF, then was postdoctoral fellow in the laboratory of Nobel laureate Prof. Stanley Prusiner.  He was a faculty member at UCLA from 1989-1994, then was recruited by the Burnham Institute to direct the Program on Aging.  In 1998 he became the Founding President and CEO of the Buck Institute for Research on Aging, and Adjunct Professor at UCSF; then in 2013 he returned to UCLA as the Director of the Easton Center for Alzheimer’s Disease Research. The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer’s disease and other neurodegenerative conditions, leading to the publication of over 220 research papers. He established the ADDN (Alzheimer’s Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer’s disease.  He and his group developed a new approach to the treatment of Alzheimer’s disease, and this approach led to the discovery of subtypes of Alzheimer’s disease, followed by the first description of reversal of symptoms in patients with MCI and Alzheimer’s disease, with the ReCODE (reversal of cognitive decline) protocol, published in 2014, 2016, and 2018.  His book, The End of Alzheimer’s, is a New York Times Bestseller.  Visit his website, https://www.ahnphealth.com/dr-bredesen.html.  Follow him on Facebook here: https://www.facebook.com/drdalebredesen/

In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer’s Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger “downsizing” in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. Dr. Bredesen received his undergraduate degree from Caltech and his medical degree from Duke. He served as Resident and Chief Resident in Neurology at UCSF, then was postdoctoral fellow in the laboratory of Nobel laureate Prof. Stanley Prusiner. He was a faculty member at UCLA from 1989-1994, then was recruited by the Burnham Institute to direct the Program on Aging. In 1998 he became the Founding President and CEO of the Buck Institute for Research on Aging, and Adjunct Professor at UCSF; then in 2013 he returned to UCLA as the Director of the Easton Center for Alzheimer’s Disease Research. The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer’s disease and other neurodegenerative conditions, leading to the publication of over 220 research papers. He established the ADDN (Alzheimer’s Drug Development Network) with Dr. Varghese John in 2008, leading to the identification of new classes of therapeutics for Alzheimer’s disease. His group has developed a new approach to the treatment of Alzheimer’s disease, and this approach has led to the discovery of subtypes of Alzheimer’s disease, followed by the first description of reversal of symptoms in patients with MCI and early Alzheimer’s disease, with the ReCODE (reversal of cognitive decline) protocol, published in 2014 and 2016. His book, The End of Alzheimer’s, is a New York Times Bestseller. To learn more about Provocative Enlightenment Radio, go to http://www.provocativeenlightenment.com

Dr Dale Bredesen is an internationally recognized researcher in Alzheimer's.  His incredible resume includes being the Director of the Easton Center for Alzheimer's Research at UCLA as well as founding president and CEO of the Buck Institute on Aging in Novato, California.  He has worked in the lab of 2 nobel prize winners and has run his own labs for 28 years looking at neurodegenerative diseases - focusing on Alzheimer's.   Dr Bredesen's fundamental theory is that Alzheimer's is actually a protective brain response to different classes of insults.   Classes of Insults Leading to Alzheimer’s Inflammation and the brain’s response to pathogens/infections – these trigger the creation of amyloid beta, a key chemical in the brain that destroys brain cell connections and is believed to be a key factor in the development of Alzheimer’s. Amyloid Beta is a part of the Innate Immune system which seems to be over stimulated or dysregulated in most cases of Alzheimer’s. Dr. Bredesen explains the connection of immune activation in Alzheimer’s. Inadequate amounts OR withdrawal of support of brain-“growing” chemicals like B12, vitamin D, and other hormones. This results in a downsizing of the networks of brain cell connections. Sugar toxicity – damages via: advanced glycation end products (AGEs) acting to damage through inflammation as well as, loss of cell supports because of shoddy insulin signaling necessary for healthy brain activity. A protective response by amyloid that bind to things that the brain perceives as a toxin – things like: copper, iron, mercury, biotoxins, infections. People in their 50s and early 60s tend to have the more “toxic” form. Problems with blood vessels and leakiness in the protective blood-brain-barrier which result in lower support chemicals and toxicity. Trauma, e.g., from things like concussions – which also lower chemical and hormone support as well as make the brain susceptible to all the insults mentioned above. The story of “Patient Zero” (Minute 28:53) Dr. Bredesen describes the first success he had with his program. Things that induce Alzheimer’s a.k.a. “Dementogens” Biotoxins Exposures to water building and the harmful effects of mold Tick exposures Heavy Metals Exposure Aluminum, copper, mercury Water damaged building, mycotoxins Certain types of infections Concussions The effects of diabetes and poor diet Certain types of pollution Not enough time asleep or insufficient oxygen when you sleep. Not enough exercise Elements of a “Cognoscopy”Because the brain changes in Alzheimer’s can creep in 20 years or more before symptoms start prevention makes a whole lot of sense. Though a cognoscopy doesn’t really exist yet in a conventional medical setting, Dr. Bredesen’s thinks that one should probably be done around age 45 to assess the risk of developing Alzheimer’s and might include the following: Genetic markers and blood work that elucidates Dr. Bredesen’s three metabolic subtypes (see an MPICognitions.com to find a doctor trained in the protocol). Functional cognitive testing using BrainHQ, Lumosity, Cog-state, CNS vital signs to see where your brain function is in a “testing environment”. Brain MRI with volumetrics (listen to Evolving Past Alzheimer’s podcast with Dr. Cyrus Raji episode #6 for full explanation) if someone has symptoms. The Role of Sleep in Alzheimer’s Time of repair (don’t eat 3 hours before bed) Time for autophagy (brain cell “pruning”) There is a slight change in the microanatomy of the brain where some of the accumulated toxicants get “washed away” Sleep hygiene is important Who typically improves with the Bredesen Program?Dr. Bredesen mentions the “MoCA” which refers to the Montreal Cognitive Assessment. This is a screening test that won’t tell you if someone has Alzheimer’s but can give you a general indication of different levels of cognitive impairment.  Dr. Bredesen mentioned that people that score 22 or greater (out of 30) are seeing improvements with his methodology.  These are people that are typically early on in their disease. Who typically does not improve with the Bredesen Program? People that are more “frail” (less able to exercise, etc.) People that are further along with the disease and have had symptoms for longer periods of time. How much improvement do people see with the Bredesen Program?Some people seem to get just a bit better in terms of mood, outlook, and brain function. Others get much better and almost completely back to their best brain function. Too early to say how many, but more than half of the people using the methodology report some sort of improvement. A discussion of an upcoming Documentary of the impact on people’s lives using Dr. Bredesen’s program.   Resources Dr. Brdesen’s Book: The End of Alzheimer’s To find a Bredesen trained physician, visit Dr. Bredesen’s website – MPI Cognition Website: Institute for Functional Medicine

Dr Dale Bredesen a clinician and researcher, has been practicing medicine for over 30 years with a focus on neurology and ageing. His lengthy experience includes being the Founding President and CEO of the Buck Institute for Research on Aging and the Director of the Easton Center for Alzheimer’s Disease Research at UCLA. The Bredesen laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer’s disease and other similar conditions. Bredesen believes that cognitive decline is a metabolically driven process with multiple causes. His research has led to the publication of over 200 research papers and has made him an internationally recognised expert in the field of Alzheimer’s and neurodegenerative processes.

Dr Dale Bredesen a clinician and researcher, has been practicing medicine for over 30 years with a focus on neurology and ageing. His lengthy experience includes being the Founding President and CEO of the Buck Institute for Research on Aging and the Director of the Easton Center for Alzheimer’s Disease Research at UCLA. The Bredesen laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer’s disease and other similar conditions. Bredesen believes that cognitive decline is a metabolically driven process with multiple causes. His research has led to the publication of over 200 research papers and has made him an internationally recognised expert in the field of Alzheimer’s and neurodegenerative processes.

Cognitive decline in early Alzheimer’s disease patients can be slowed, and in some cases reversed, by a novel, personalized, integrative program designed by neurologist Dale E. Bredesen, MD from the Mary S. Easton Center for Alzheimer’s Disease Research, Department of Continue reading Alzheimer’s Disease and Cognitive Decline Helped by a Personalized, Integrative Approach – An Interview With Dale E. Bredesen, MD→ The post Alzheimer’s Disease and Cognitive Decline Helped by a Personalized, Integrative Approach – An Interview With Dale E. Bredesen, MD appeared first on .