Podcasts about Mitigation

Reduction of something harmful or the reduction of its harmful effects

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Best podcasts about Mitigation

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Latest podcast episodes about Mitigation

Words & Numbers
Episode 486: Slavery and Capitalism

Words & Numbers

Play Episode Listen Later Jan 1, 2026 47:57


In this episode, we discuss public distrust of politicians and the realities behind presidential approval polling before turning to the math of lotteries and why people continue to play despite the odds. We examine Maryland's proposed reparations commission, including questions of eligibility, funding, legal responsibility, and the practical challenges of tying modern policy to historical injustice. We're joined by Phil Magness to explore the economic history of slavery, the claim that capitalism was built on slave labor, and why slavery is fundamentally incompatible with free markets. We cover Adam Smith's opposition to slavery, misconceptions about profit incentives, the global history of forced labor, and the moral and economic failures surrounding emancipation, closing with a broader discussion of capitalism, socialism, and historical accountability. 00:00 Introduction and Overview 00:44 Presidential Approval Ratings and Polling Reality 02:38 Why Americans Have Always Hated Politicians 03:35 Powerball, Probability, and the Math of Dreaming 06:51 Maryland's Reparations Commission Explained 08:12 Who Pays and Who Gets Reparations? 10:03 Mitigation, Law, and the Reparations Problem 14:24 Introducing Phil Magness 15:02 Was Capitalism Built on Slavery? 17:59 Slavery as an Ancient Institution 19:50 Adam Smith's Case Against Slavery 23:05 Why Slavery Is Anti-Capitalist 24:50 Pro-Slavery Economics and Feudalism 26:16 Founding Fathers, Hypocrisy, and Moral Failure 30:21 Slavery's Global History and Misconceptions 32:06 Incentives, Profit, and Economic Naivety 34:53 Would Slavery Have Ended Without the Civil War? 37:59 Gradual Emancipation and Historical Alternatives 40:47 Socialism, Capitalism, and the Plantation Model 44:01 Final Reflections and Closing Thoughts Learn more about your ad choices. Visit podcastchoices.com/adchoices

Rare Disease Discussions
AI in Medicine: Transforming the Landscape of Tissue-Based Diagnostics

Rare Disease Discussions

Play Episode Listen Later Dec 31, 2025 52:29


Behzad Najafian, MD, Professor, Department of Laboratory Medicine & Pathology, Department of Medicine at the University of Washington, Washington, USA discusses the use of artificial intelligence in identifying and managing lysosomal disorders.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees.To obtain CME/CE credit, visit https://checkrare.com/learning/p-grids2025-session1-ai-in-medicine-transforming-the-landscape-of-tissue-based-diagnostics/Learning ObjectivesDescribe recent advances in the applications of AI in lysosomal disorder diagnosis and its clinical relevanceFacultyBehzad Najafian, MD Professor, Department of Laboratory Medicine & Pathology, Department of Medicine, University of WashingtonDisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Behzad Najafian, MDDr. Najafian is on the Advisory Board/Consultant for Sanofi, Amicus, Avrobio, 4DMT,Sangamo, Freeline, AceLink, Relay, CRISPR, ELOXX, SPARK, UNIQURE. He receives grants/research support from Amicus. Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Conflicts of interest for presenting faculty with relevant financial interests were resolved through peer review of content by a non-conflicted reviewer.Accreditation and Credit DesignationPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesAffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit.Nurse PractitionersAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Genetic Counselors should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity. Participation CostsThere is no cost to participate in this activity.CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.comSend customer support requests to cds_support+ldrtc@affinityced.com

Rare Disease Discussions
Nanotechnology and Lysosomal Disorders

Rare Disease Discussions

Play Episode Listen Later Dec 31, 2025 50:18


Stephan Stern, PhD, DABT, Director of Research and Development, Nanotechnology Characterization Lab (NCL), Frederick National Laboratory for Cancer Research, Maryland, USA; and Ruben Boado, PhD, Professor of Medicine, University of California at Los Angeles, California, USA, discuss the use of nanotechnology in the treatment of lysosomal disorders.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees.To obtain CME/CE credit, visit https://checkrare.com/learning/p-grids2025-session2-nanotechnology-and-lysosomal-disorders/Learning ObjectivesDescribe recent advances in the use of nanotechnology to treat lysosomal disordersDescribe the role of nanotechnology in addressing unmet needs in lysosomal disordersFacultyStephan Stern, PhD, DABTDirector of Research and Development, Nanotechnology Characterization Lab (NCL), Frederick National Laboratory for Cancer ResearchRuben Boado, PhDProfessor of Medicine, University of California at Los AngelesDisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Stephan Stern, PhD, DABTDr. Stern has no relevant financial relationships to disclose. Ruben Boado, PhDDr. Boado has no relevant financial relationships to disclose.Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Conflicts of interest for presenting faculty with relevant financial interests were resolved through peer review of content by a non-conflicted reviewer.Accreditation and Credit DesignationPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesAffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit.Nurse PractitionersAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Genetic Counselors should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity. Participation CostsThere is no cost to participate in this activity.CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.comSend customer support requests to cds_support+ldrtc@affinityced.com

Rare Disease Discussions
Organoids and Lab-Grown Models in Lysosomal Disorders

Rare Disease Discussions

Play Episode Listen Later Dec 31, 2025 96:02


Mia Horowitz, PhD, Tel Aviv University; Aitor Aguirre, PhD, Michigan State University, Michigan, USA; and Ying Sun, PhD, University of Cincinnati, discuss the use of organoid models in lysosomal disorder research and drug development.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees.To obtain CME/CE credit, visit https://checkrare.com/learning/p-grids2025-session3-organoids-and-lab-grown-models-in-lysosomal-disorders/Learning ObjectivesDescribe the use of heart organoid models to better understand the pathophysiology of lysosomal disorders and its clinical relevanceDescribe the use and application of brain organoid models in neuropathic Gaucher disease research and treatmentFacultyMia Horowitz, PhD, Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University.Aitor Aguirre, PhD, Associate Professor of Biomedical Engineering, Institute for Quantitative Health Science and Engineering, Chief, Division of Developmental and Stem Cell Biology (IQ), Director, MSU Stem Cell Core, Michigan State University.Ying Sun, PhD, Professor, Cincinnati Children's Hospital Medical Center, University of Cincinnati.DisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Mia Horowitz, PhDDr. Horowitz has no relevant financial relationships to disclose.Aitor Aguirre, PhDDr. Aguirre has no relevant financial relationships to disclose.Ying Sun, PhDDr. Sun receives research support from Enkefalos Biosciences and Yuhan Corporation.Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Conflicts of interest for presenting faculty with relevant financial interests were resolved through peer review of content by a non-conflicted reviewer.Accreditation and Credit DesignationPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesAffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit.Nurse PractitionersAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Genetic Counselors should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity. Participation CostsThere is no cost to participate in this activity.CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.comSend customer support requests to cds_support+ldrtc@affinityced.com

Rare Disease Discussions
Expanded Applications of AI in Lysosomal Disorders

Rare Disease Discussions

Play Episode Listen Later Dec 31, 2025 121:27


Oral Alpan, MD, Immunologist, Amerimmune, Virginia, USA; Svenja Keller, PhD student, University of Zurich, Switzerland; Shoshana Revel-Vilk, MD, PhD, Director, Gaucher Unit & Pediatric Hematology/Oncology Unit, Shaare Zedek Medical Center, Jerusalem, Israel; Patrick Deegan, MD, Consultant Metabolic Physician, University of Cambridge, UK; and Ravi Kamath, MD, PhD, Head of Musculoskeletal Radiology, Inova Health System, Virginia, USA, discuss the applications of AI in the diagnosis and treatment of lysosomal disorders.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees.To obtain CME/CE credit, visit https://checkrare.com/learning/p-grids2025-session4-expanded-applications-of-ai-in-lysosomal-disorders/Learning ObjectivesDescribe how emerging AI and machine learning technologies are advancing disease modeling and biomarker development.Describe how emerging AI and machine learning technologies are advancing therapeutic target identification across lysosomal disorders.FacultyOral Alpan, MD, Immunologist, AmerimmuneSvenja Keller, PhD student, University of ZurichShoshana Revel-Vilk, MD, PhD, Director, Gaucher Unit & Pediatric Hematology/Oncology Unit, Shaare Zedek Medical CenterPatrick Deegan, MD, Consultant Metabolic Physician, University of CambridgeRavi Kamath, MD, PhD, Head of Musculoskeletal Radiology, Inova Health SystemDisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Oral Alpan, MD Dr. Alpan has no relevant financial relationships to disclose.Svenja KellerMs. Keller has no relevant financial relationships to disclose.Shoshana Revel-Vilk, MD, PhDDr. Revel-Vilk receives grant/research support from Sanofi and Takeda. She is a member of the Speakers Bureau for Sanofi and Takeda, and a member of the Advisory Board for Takeda.Patrick Deegan, MDDr. Deegan is a consultant and advisory board member with Sanofi, Takeda, and Amicus.He also receives research support from Sanofi and Amicus.Ravi Kamath, MD, PhDDr. Kamath is on an advisory board for Intrinsic Therapeutics. He is also a consultant forSanofi, Takeda, and Spur Therapeutics.Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Conflicts of interest for presenting faculty with relevant financial interests were resolved through peer review of content by a non-conflicted reviewer.Accreditation and Credit DesignationPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesAffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit.Nurse PractitionersAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Genetic Counselors should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity. Participation CostsThere is no cost to participate in this activity.CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.comSend customer support requests to cds_support+ldrtc@affinityced.com

Rare Disease Discussions
Theranostics and Lysosomal Disorders

Rare Disease Discussions

Play Episode Listen Later Dec 31, 2025 106:09


Duarte C. Barral, PhD, Associate Professor, NOVA Medical School, NOVA University of Lisbon, Portugal; Nuno Raimundo, PhD, Associate Professor, Department of Cellular and Molecular Physiology; Penn State College of Medicine, Pennsylvania, USA; Betul Celik, PhD, Postdoctoral Fellow, Nemours Children's Health, Delaware, USA; and Gregory Newby, PhD, Assistant Professor, Department of Genetic Medicine, Johns Hopkins School of Medicine, Maryland, USA,discuss the principles of theranostics and its application in lysosomal disorders.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees.To obtain CME/CE credit, please visit https://checkrare.com/learning/p-grids2025-session5-theranostics-and-lysosomal-disorders/ Learning ObjectivesDescribe lysosomal and inter-organelle mechanisms that contribute to pathology in lysosomal disorders, and how these pathways are being leveraged for diagnostic and therapeutic applications.Describe current and emerging theranostic strategies for lysosomal disorders.FacultyDuarte C. Barral, PhD, Associate Professor, NOVA Medical School, NOVA University of Lisbon, Nuno Raimundo, PhD, Associate Professor, Department of Cellular and Molecular Physiology; Penn State College of MedicineBetul Celik, PhD, Postdoctoral Fellow, Nemours Children's HealthGregory Newby, PhD, Assistant Professor, Department of Genetic Medicine, Johns Hopkins School of MedicineDisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Duarte C. Barral, PhD Dr. Barral's group receives grant support from Sea4Us.Nuno Raimundo, PhDDr. Raimundo has no relevant financial relationships to disclose.Betul Celik, PhDDr. Celik has no relevant financial relationships to disclose.Gregory Newby, PhDDr. Newby has no relevant financial relationships to disclose.Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Conflicts of interest for presenting faculty with relevant financial interests were resolved through peer review of content by a non-conflicted reviewer.Accreditation and Credit DesignationPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesAffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit.Nurse PractitionersAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Genetic Counselors should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity. Participation CostsThere is no cost to participate in this activity.CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.comSend customer support requests to cds_support+ldrtc@affinityced.com

Rare Disease Discussions
Current Issues in Gene Therapies for Lysosomal Disorders

Rare Disease Discussions

Play Episode Listen Later Dec 31, 2025 106:41


Shunji Tomatsu, MD, PhD, Professor and Head, Nemours Children's Health, Delaware, USA; Alessandra d'Azzo, PhD, Emerita Faculty, Genetics, St. Jude Children's Research Hospital, Tennessee, USA; Merve Emecen Sanli, MD, Associate Professor, Department of Pediatrics, University of Texas Southwestern Medical Center, Texas, USA; and Ryan Colburn, patient with Pompe disease and president of Odimm Inc, discuss new and emerging gene therapies for lysosomal disorders.This continuing education activity is provided through collaboration between the Lysosomal and Rare Disorders Research and Treatment Center (LDRTC), CheckRare CE, and AffinityCE. This activity provides continuing education credit for physicians, physician assistants, nurses, nurse practitioners, and genetic counselors. A statement of participation is available to other attendees.To obtain CME/CE credit, please visit https://checkrare.com/learning/p-grids2025-session6-current-issues-in-gene-therapies-for-lysosomal-disorders/  Learning ObjectivesDescribe current and emerging gene therapy data in lysosomal disorders and its clinical relevanceDescribe role of patients in gene therapy developmentFacultyShunji Tomatsu, MD, PhD, Professor and Head, Nemours Children's HealthAlessandra d'Azzo, PhD, Emerita Faculty, Genetics, St. Jude Children's Research HospitalMerve Emecen Sanli, MD, Associate Professor, Department of Pediatrics, University of Texas Southwestern Medical CenterRyan Colburn. Odimm, Inc.DisclosuresAffinityCE staff, LDRTC staff, planners, and reviewers, have no relevant financial relationships with ineligible companies to disclose. Faculty disclosures, listed below, will also be disclosed at the beginning of the Program.Shunji Tomatsu, MD, PhD Dr. Tomatsu has received the following grants: Morquio Foundations and families: Scarlett Grifith, Bennett, A Cure for Roberts, and Morquio Conference; MPS Societies: Japanese, National, and Austrian; NIH grants: 1-R01-HD102545, NIH, NICHD, Tomatsu (PI), 1R01HD104814-01A1, NIH, NICHD, Langan, T.J. (PI), Role: Site-PI, R43HD114328-01, NIH, ACOSTA, WALTER (PI), Role: site PI, 1R43AR084638-01, NIH, MOUNZIH, KHALID (PI); Foundation of NIH: FNIH RFP NUMBER: 2022-BGTC-005 Tomatsu (PI). Alessandra d'Azzo, PhDDr. D'Azzo has no relevant financial relationships to disclose.Merve Emecen Sanli, MDDr. Sanli has no relevant financial relationships to disclose.Ryan ColburnMr. Colburn has an advisory, consulting and/or project based relationship or stock holding with: Abeona Therapeutics, Amicus Therapeutics, Astellas Gene Therapies, Avidity Biosciences, Bayer, Catalyst Pharmaceuticals, Denali Therapeutics, M6P Therapeutics, Sangamo Therapeutics, Sanofi, Solid Biosciences.Mitigation of Relevant Financial RelationshipsAffinityCE adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CME activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Conflicts of interest for presenting faculty with relevant financial interests were resolved through peer review of content by a non-conflicted reviewer.Accreditation and Credit DesignationPhysiciansThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of AffinityCE and the LDRTC. AffinityCE is accredited by the ACCME to provide continuing medical education for physicians.AffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.Physician AssistantsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Physician Assistants should claim only the credit commensurate with the extent of their participation in the activity.NursesAffinityCE is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation (ANCC). This activity provides a maximum of 1 hours of continuing nursing education credit.Nurse PractitionersAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Nurse practitioners should claim only the credit commensurate with the extent of their participation in the activity.Genetic CounselorsAffinityCE designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credits™. Genetic Counselors should claim only the credit commensurate with the extent of their participation in the activity.Other ProfessionalsAll other health care professionals completing this continuing education activity will be issued a statement of participation indicating the number of hours of continuing education credit. This may be used for professional education CE credit. Please consult your accrediting organization or licensing board for their acceptance of this CE activity. Participation CostsThere is no cost to participate in this activity.CME InquiriesFor all CME policy-related inquiries, please contact us at ce@affinityced.comSend customer support requests to cds_support+ldrtc@affinityced.com

i want what SHE has
407 JoAnn Stevelos "The Hope Model"

i want what SHE has

Play Episode Listen Later Dec 30, 2025 110:11


Today, I get to sit down with returning guest, JoAnn Stevelos, MS, MPH. She is a writer, public health advisor, and researcher whose work sits at the intersection of survival, spiritual terror, radical repair, and relational hope. With more than twenty years' experience in nonprofits, government, public health research, bioethics, and education, she uses her training to help create a culture of health through innovative solutions that treat health as a fundamental human right. Her Robert Wood Johnson Foundation–funded work in Aotearoa New Zealand inspired her to adopt a Samoan proverb as a north star: “Solutions for the community come from the community.”JoAnn is currently the Executive Director of the Andrew Levitt Center for Social Emergency Medicine. She has served in key leadership roles including Executive Director of the Coalition for Supportive Care of Kidney Patients at George Washington University; Director of the NYS Center for the Prevention of Childhood Obesity; Director of Evaluation for the Alliance for a Healthier Generation and Michelle Obama's Let's Move! campaign; and Monitoring and Evaluation Advisor for the RWJF-funded Comprehensive Child Sexual Abuse Prevention, Treatment, and Mitigation program in New Zealand. She advises national and international nonprofits that address health disparities and inequities. A founding board member of The Hope Institute, she has served on the boards of Eat REAL and the New York State Public Health Association. She is a graduate of Columbia University and the University at Albany School of Public Health and Albany Medical College.As a writer, JoAnn's work spans memoir, fiction, poetry, and performance. A Pushcart and Best American Essays nominee, her essays have appeared in The Guardian— “This story isn't about the priest who abused me. It's about my mother.” , Chicago Story Press “How Do You Forgive the Unforgivable?”, and The DewDrop“Passersby” . She is the author of the novel Howard Be Thy Name  and the cross-genre collection Dream Alibis,, and writes the Substack The Second Silence. Her essay “Mugwort” received distinction in the 2025 Writer's Digest Personal Essay Awards, and “The Archivist,” created in collaboration with photographer Sarah Blesener, is forthcoming in North American Review. JoAnn is represented by Barbara Jones at Stuart Krichevsky Literary Agency.Today we focus our conversation on The Hope Model that JoAnn began exploring over 5 years ago. We talk about hopelessness and its many forms and how an awareness of the 4 elements of The Hope Model - Survival, Mastery, Attachment and Spirituality - can help to build hope.The Hope Institute offers Hope Assessments as well as The Oxford Compendium of Hope. Stay tuned to their work as they continue to offer resources and support to a world that sometimes feels in dire need of more hope.You can find more about JoAnn and her work below:https://linktr.ee/JoAnnStevelosChildren at the Table~Psychology Today Blog Dream AlibisToday's show was engineered by Ian Seda from Radiokingston.org.Our show music is from Shana Falana!Feel free to email me, say hello: she@iwantwhatshehas.org** Please: SUBSCRIBE to the pod and leave a REVIEW wherever you are listening, it helps other users FIND IThttp://iwantwhatshehas.org/podcastITUNES | SPOTIFYITUNES: https://itunes.apple.com/us/podcast/i-want-what-she-has/id1451648361?mt=2SPOTIFY:https://open.spotify.com/show/77pmJwS2q9vTywz7Uhiyff?si=G2eYCjLjT3KltgdfA6XXCAFollow:INSTAGRAM * https://www.instagram.com/iwantwhatshehaspodcast/FACEBOOK * https://www.facebook.com/iwantwhatshehaspodcast

America Adapts the Climate Change Podcast
Arizona's Climate Change Adaptation Playbook: Heat, Water, Wildfire

America Adapts the Climate Change Podcast

Play Episode Listen Later Dec 29, 2025 97:44


In episode 244 of America Adapts, we adapt in the southwest! Welcome to the desert proving ground for climate adaptation. In my home state of Arizona—Phoenix, Tucson, and Flagstaff—we get right down on the ground to see how communities are beating extreme heat, planning responsibly for water in a changing climate, and living with wildfire risk without losing what makes these places home. You'll hear street-level fixes that change daily life—and travel anywhere—plus a clear playbook cities can steal now: run the hottest months smarter, put shade where people actually stand and walk, and build the partnerships that keep projects alive. We also spotlight the next wave of adaptation pros coming out of Arizona's universities and city halls—real careers, real impact. If it works in the desert, parts of it can work where you live. Made possible by generous support from the CO2 Foundation. Experts in this Episode: Dr. Ladd Keith – Associate Professor in the School of Landscape Architecture and Planning at the University of Arizona Fatima Luna – Chief Resilience Officer City of Tucson Blue Baldwin – Storm to Shade Program Manager at Tucson Water for the City of Tucson Alekzander Ryan - Heat Resilience Initiative, Southwest Integrated Field Laboratory David Hondula - Director of Heat Response and Mitigation for the City of Phoenix Ryan Stevens – Engineering manager with the City of Phoenix Nicole P. Antonopoulos  –  Sustainability Director City of Flagstaff Sustainability Office Victoria Joseph and Leona Davis - University of Arizona's Institute for Resilience This episode was generously sponsored by the CO2 Foundation. Check out the America Adapts Media Kit here! Subscribe to the America Adapts newsletter here. Donate to America Adapts Facebook, Linkedin and Twitter: https://www.facebook.com/americaadapts/ @usaadapts https://www.linkedin.com/in/doug-parsons-america-adapts/ Links in this episode: https://climateaction.tucsonaz.gov/pages/gsi https://www.awwa.org/AWWA-Articles/tucsons-storm-to-shade-program-creates-a-cooler-city/ https://www.flagstaff.az.gov/4687/Meet-the-Sustainability-Team https://www.phoenix.gov/administration/departments/heat/heat-response-programs/heat-response-plan.html https://www.abc15.com/news/local-news/phoenix-fights-urban-heat-with-expanding-cool-pavement-program-that-lowers-street-temperatures https://www.phoenix.gov/content/dam/phoenix/oepsite/documents/climate/Heat.CAPWorkshops%202025%20AllSlides.pdf https://www.coolseal.com/blog/az-family   Hiking Recommendations!  https://tucsontopia.com/tanque-verde-falls/ https://wildpathsaz.com/pusch-peak/ https://www.arizonahighways.com/cochise-trail https://adventuresofaplusk.com/bear-canyon-to-seven-falls-trail/?srsltid=AfmBOopxtf54vPgFb6XX5rSiwzwPpfIXezBijXK_ClrUyed7McDH5TFx   Doug Parsons and Speaking Opportunities: If you are interested in having Doug speak at corporate and conference events, sharing his unique, expert perspective on adaptation in an entertaining and informative way, more information can be found here! Facebook, Linkedin and Twitter: https://www.facebook.com/americaadapts/ https://bsky.app/profile/americaadapts.bsky.social https://www.linkedin.com/in/doug-parsons-america-adapts/ Donate to America Adapts Follow on Apple Podcasts Follow on Android Now on Spotify! List of Previous Guests on America Adapts Follow/listen to podcast on Apple Podcasts. Donate to America Adapts, we are now a tax deductible charitable organization! The 10 Best Sustainability Podcasts for Environmental Business Leadershttps://us.anteagroup.com/news-events/blog/10-best-sustainability-podcasts-environmental-business-leaders Join the climate change adaptation movement by supporting America Adapts!  Please consider supporting this podcast by donating through America Adapts fiscal sponsor, the Social Good Fund. All donations are now tax deductible! For more information on this podcast, visit the website at http://www.americaadapts.org and don't forget to subscribe to this podcast on Apple Podcasts.   Podcast Music produce by Richard Haitz Productions Write a review on Apple Podcasts ! America Adapts on Facebook!   Join the America Adapts Facebook Community Group. Check us out, we're also on YouTube! Subscribe to America Adapts on Apple Podcasts Doug can be contacted at americaadapts @ g mail . com

Rare Disease Discussions
Ch 3: Mitigation Strategies to Address the Challenges in the Development of Gene Therapy Programs

Rare Disease Discussions

Play Episode Listen Later Dec 22, 2025 5:40


Alan Beggs, PhDDirector of the Manton Center for Orphan Disease ResearchSir Edwin and Lady Manton Professor of Pediatrics, Boston Children's HospitalHarvard Medical School, Boston, MA, USAThe challenges that you've heard about are real. Some of them I think we could have foreseen others. There was no way to know until we actually started treating patients in clinic. But we now know that there are immune responses and also responses just to the viral load. As Julie mentioned, we're giving massive doses to these patients on the order of one times ten to the 14 viral genomes per kilogram.Think about the fact that when these capsids are manufactured, there's a certain percentage of empty capsid. The amount of protein that's being delivered to these patients can be massive. One of the approaches to mitigate some of the risk would be to lower the dose. While early studies demonstrated that in order to get adequate delivery to skeletal muscle, you need to give these very large doses. But what if we could engineer a viral capsid that would be potent at lower doses?There has been quite a bit of research in this area that's ongoing, and some new next generation vectors that are just starting to enter the clinic. In particular, there are a class of Myotropic viral vectors or capsids so-called RGD vectors. RGD refers to arginine, glycine, and aspartic acid, which are three residues which, when present at a particular point in the viral capsid proteins interact with integrin receptors that are specific for skeletal muscle. These viral capsids home to skeletal muscle and can deliver their genetic payload at much lower doses. There was one group of these developed in Germany by Theo Grimm's lab.These were the so-called AAV Myos, and simultaneously in Boston at the Broad Institute, a group of capsids was developed that were called Myo AAV. These were both based off of an AAV nine backbone. It's basically an AAV nine legacy vector with these three amino acids changed. Now Solid Biosciences also has their own independently derived vector that I believe is also an RGD vector. These vectors give us the potential then for more efficient and specific delivery to muscle cells.They may or may not target the liver depending on the particular virus. Some of them the risk to the liver is mitigated by delivering a lower dose. You can also develop these vectors in a way that will be liver targeted, that specifically less of it gets delivered to the vectors. These would be really, in my mind potentially third generation vectors.Strategies, there are a number of strategies. You heard about the immunomodulation regimens. I just talked about optimizing vector design. Also, Doctor Parsons mentioned earlier the fact that where you deliver so zolgensma is delivered Intrathecally. We get it to the place we need it, and we're less likely to have off target effects through other tissues.Then improved manufacturing is very important. I mentioned the fact that every viral preparation contains empty capsids. There are ways to minimize the production of empty capsids, and also effective ways to filter out and remove those empty capsids. This is actually a very important aspect that is being developed further by the CMO community. Then in summary, I think it's important to take a holistic approach when we're thinking about the development of AAV based gene therapies for neuromuscular disease.It starts from the fact that for any given disease we're interested in, we need to define the genetic etiology. Since these are gene directed therapies. We need to pay careful attention to the preclinical animal models. How accurately do they really reflect the human condition? Or are there potentially responses in our human patients that we haven't experienced in the animals? It's important to understand the natural history and the patient population.Recognize that there's extensive heterogeneity, not just in age and severity, but also potentially in underlying susceptibilities in our patients. We have a group of toxicities that we know about and can anticipate. But as Julie was saying, you need to be really careful and think about any potential unexpected SAEs. And then finally I mentioned the manufacturing aspect, the development of newer vectors and quality control aspects that go into making a safe and effective therapeutic.In the next part. Doctor Parsons will discuss clinical safety and efficacy observed in AAV mediated gene therapy programs in DMD, SMA, and XLMTM.

Scope of Practice
Mitigation Specialists: The Aim for Outcomes That Consider Rehabilitation and Not Just Punishment

Scope of Practice

Play Episode Listen Later Dec 19, 2025 35:53


Mitigation Specialist and President of the Connecticut Women's Consortium Dr. Jozlyn Hall joins us to talk about the scope of her work as a member of the criminal defense team and how it impacts sentencing in cases before the court Originally used solely in capital cases, it is not about excusing individuals of the responsibility of their actions, but for getting the accused the assistance they need based on a complete evaluation of their strengths, deficits and needs. Given that the needs may include SUD services, it is an important area for professionals working with justice-involved individuals to understand.

Fire Science Show
231 - BESS explosion prevention and mitigation with Lorenz Boeck and Nick Bartlett

Fire Science Show

Play Episode Listen Later Dec 17, 2025 59:50 Transcription Available


Today we cover another branch of safety of Battery Energy Storage Systems (BESS), that is explosion prevention in mitigation. I always thought you can either end with a fire or with an explosion, and boy I was wrong... but we will go back to this later. Now I bring on Dr. Lorenz Boeck (REMBE) and Nick Bartlett (Atar Fire) to unpack how gas released during thermal runaway turns a container into a deflagration hazard, and what it takes to design systems that actually manage the pressure, flame, and fallout. This is a tour through real incident learnings, rigorous lab data, and the evolving standards that now shape best practice.We start with the fundamentals: from the overview given by NFPA855, why modern BESS enclosures—with higher energy density and less free volume—see faster pressure rise, how gas composition varies by cell and manufacturer, and why stratification matters when lighter hydrogen-rich mixtures sit above heavier electrolyte vapors. From there, we translate UL 9540A outputs—gas quantity, composition, flammability limits, burning velocity—into engineering decisions. NFPA 69's prevention path typically relies on gas detection and mechanical ventilation designed to keep concentrations below 25% LFL, validated with CFD to capture obstructions, sensor placement, fan ramp, and louver timing. NFPA 68's mitigation path kicks in if ignition happens, with certified vent panels sized to the actual reactivity and geometry, relieving pressure and directing flame away from exposures.A major takeaway: the latest NFPA 855 now often pushes for both prevention and protection. Even with active ventilation, partial-volume deflagration hazards remain, especially as cell capacities rise and gas volumes scale up. We dig into venting trade-offs—roof vs sidewall, snow and hail loading, heat flux to back-to-back units—and how targeted sidewall venting can deflect flame upward while reducing weather vulnerabilities. Perhaps most critical, we talk about late deflagrations observed hours into large-scale fire tests, when changing ventilation conditions allow pockets to ignite. Active systems aren't built to operate throughout a long fire, so passive venting becomes essential during and after ignition.Whether you're a fire engineer, AHJ, insurer, or developer, this conversation connects the dots between lab data, CFD, and field realities. You'll leave with a clearer view of how to apply UL 9540A, NFPA 68, NFPA 69, and NFPA 855 in a world of stacked containers and supersized cells—plus where training can shorten your learning curve. If you are interested by the course given by colleagues in Lund in January 2026 - here it is: https://www.atarfire.com/event-details/nfpa-855-8-hour-training-lund-university----The Fire Science Show is produced by the Fire Science Media in collaboration with OFR Consultants. Thank you to the podcast sponsor for their continuous support towards our mission.

KuppingerCole Analysts
Mastering Web Scraping Defense with Qrator Labs: AI-Driven Threats & Modern Mitigation

KuppingerCole Analysts

Play Episode Listen Later Dec 17, 2025 23:43


Web scraping has entered a new era and AI is changing everything. In this videocast, Osman Celik speaks with Dmitriy Loshakov from QRator Labs to explore how automated data collection has evolved from simple crawling into highly adaptive, human-like scraping attacks that operate invisibly. You’ll learn: ✅ What web scraping actually is (and why not all scraping is malicious)✅ How AI-powered scrapers mimic real user behavior with mouse movements, delays & clicks✅ Why classic defenses like CAPTCHAs and JS challenges no longer stop modern bots✅ The industries hit hardest — from e-commerce and travel to betting, finance, and media✅ How organizations can defend themselves using behavioral analysis & intent detection✅ Why the future of cybersecurity is officially AI vs. AI

KuppingerCole Analysts Videos
Mastering Web Scraping Defense with Qrator Labs: AI-Driven Threats & Modern Mitigation

KuppingerCole Analysts Videos

Play Episode Listen Later Dec 17, 2025 23:43


Web scraping has entered a new era and AI is changing everything. In this videocast, Osman Celik speaks with Dmitriy Loshakov from QRator Labs to explore how automated data collection has evolved from simple crawling into highly adaptive, human-like scraping attacks that operate invisibly. You’ll learn: ✅ What web scraping actually is (and why not all scraping is malicious)✅ How AI-powered scrapers mimic real user behavior with mouse movements, delays & clicks✅ Why classic defenses like CAPTCHAs and JS challenges no longer stop modern bots✅ The industries hit hardest — from e-commerce and travel to betting, finance, and media✅ How organizations can defend themselves using behavioral analysis & intent detection✅ Why the future of cybersecurity is officially AI vs. AI

Set For Sentencing
Year End Review (White Collar Support Presentation)

Set For Sentencing

Play Episode Listen Later Dec 15, 2025 81:46


It's the last podcast of the year, and what better way to end than with a presentation to the amazing group, White Collar Support (www.prisonist.org).  I was grateful to have the opportunity to present to this community, a brainchild of attorney Jeff Grant.    It's particularly fitting for a 2025 finale, as the hour is a recap of the effective sentencing strategies we've been discussing on this podcast, and deploying in our own cases. Please like, share and subscribe.  Have great holidays.  Drink a responsible amount of great tequila, and we will see you in 2026!!!   IN THIS EPISODE:  Doug Passon's story!  Including Mitigation Filmmaking, Sentencing Consulting, and Autism-informed criminal defense; Narrative is everything; Defense Maps; The "3Rs" of mitigation narrative; There are at least TWO SENTENCINGS that occur in every case; Mitigation development must start EARLY; Use of qualified experts to bolster sentencing narratives; Choosing your prison experts wisely – all are not created equal; Effectively using sentencing and life expectancy statistics; The nuts and bolts of sentencing mitigation films; The value (or lack thereof) of sentencing letters; The power of allocution; Tips for choosing the very best lawyer for your case.   LINKS:   White Collar Support:  https://prisonist.org/ Defense Maps:  https://www.defensemap.com/ Sentencing Statistics:  www.sentencingstats.com Dr. Not Guilty, by Muhamad Aly Rifai, MD.  The Simpsons Do Mitigation Videos!? (Clip from Season 30, ep. 15, "101 Mitigations") FREE DOWNLOADS:  CLICK HERE TO VISIT MAINPAGE  of the podcast for downloads: CHAPTER EIGHT OF DR. NOT GUILTY -- CHOSSING YOUR DEFENDER 3RS OF SENTENCING NARRATIVE (BY DOUG PASSON) SAMPLE SENTENCING LETTER REQUEST (BY DOUG PASSON)

NACE International Podcasts
Heat-Flex Coatings: Sherwin-Williams Targets CUI Mitigation

NACE International Podcasts

Play Episode Listen Later Dec 11, 2025 22:23


With an innovation known as “Heat-Flex CUI mitigation coatings,” Sherwin-Williams Protective & Marine earned industry recognition as a winner in the 2025 Materials Performance (MP) Corrosion Innovation of the Year Awards program. MP is a member magazine of the Association for Materials Protection and Performance (AMPP). Neil Wilds, global product director for corrosion under insulation (CUI) and testing at Sherwin-Williams, joins this episode alongside Kristin Leonard, energy marketing director for North America. In a conversation with AMPP Media's Ben DuBose, Wilds and Leonard explain how the Heat-Flex CUI line came to be; marketplace trends and feedback from the field; and what the future could hold in 2026 and beyond.

Robert McLean's Podcast
Climate News: Richard Denniss warns that recovery could outstrip either mitigation or adaptation; The problem with climate-induced bushfires again troubling New South Wales

Robert McLean's Podcast

Play Episode Listen Later Dec 7, 2025 11:28


The Australia Institute's joint CEO, Richard Denniss, (pictured) was one of a trio of guest speakers several weeks ago at an event organised by The Royal Society of Victoria, warning of the emerging problems of recovery from weather-related disasters arising from climate change.‘"Just heartbreak': At least a dozen homes lost in bushfires near Sydney";"‘Crippling prices': Manufacturers demand gas reservation";"The $265 million commute: How urban sprawl is costing Melbourne";"What do we know about climate change? How do we know it? And where are we headed?".

Unofficial SAP on Azure podcast
#270 - TOW Azure Central Point of Connectivity and Advanced Threat Mitigation (Evren Buyruk, Saleem Bseeu) | SAP on Azure Video Podcast

Unofficial SAP on Azure podcast

Play Episode Listen Later Dec 5, 2025 61:35


In episode 270 of our SAP on Azure video podcast we talk about Azure Network Security. In recent episodes we talked about securing your SAP systems using Entra ID, implementing MFA or using Sentinel to detect attacks. But what about the foundation, the Azure Network? So today I am glad to have Evren and Saleem with us to take a closer look at Azure Central Point of Connectivity and Advanced Threat Mitigation. Find all the links mentioned here: https://www.saponazurepodcast.de/episode270Reach out to us for any feedback / questions:* Goran Condric: https://www.linkedin.com/in/gorancondric/* Holger Bruchelt: https://www.linkedin.com/in/holger-bruchelt/ #Microsoft #SAP #Azure #SAPonAzure #Networking #Security #DDoS #ExpressRoute

The Manila Times Podcasts
OPINION: Adaptation, mitigation and resilience to climate change | Dec. 6, 2025

The Manila Times Podcasts

Play Episode Listen Later Dec 5, 2025 4:05


OPINION: Adaptation, mitigation and resilience to climate change | Dec. 6, 2025Subscribe to The Manila Times Channel - https://tmt.ph/YTSubscribe Visit our website at https://www.manilatimes.net Follow us: Facebook - https://tmt.ph/facebook Instagram - https://tmt.ph/instagram Twitter - https://tmt.ph/twitter DailyMotion - https://tmt.ph/dailymotion Subscribe to our Digital Edition - https://tmt.ph/digital Check out our Podcasts: Spotify - https://tmt.ph/spotify Apple Podcasts - https://tmt.ph/applepodcasts Amazon Music - https://tmt.ph/amazonmusic Deezer: https://tmt.ph/deezer Stitcher: https://tmt.ph/stitcherTune In: https://tmt.ph/tunein#TheManilaTimes#KeepUpWithTheTimes Hosted on Acast. See acast.com/privacy for more information.

Research To Practice | Oncology Videos
Toxicities Associated with CAR T-Cell Therapy — An Interview with Dr Matthew Lunning (Companion Faculty Lecture)

Research To Practice | Oncology Videos

Play Episode Listen Later Dec 4, 2025 34:03


Featuring a slide presentation and related discussion from Dr Matthew Lunning, including the following topics: Overview of available chimeric antigen receptor (CAR) T-cell therapies (0:00) Toxicities associated with CAR T-cell therapy (4:03) Mitigation strategies for adverse events (22:02) Novel strategies for outpatient infusion (26:34) Changes to the CAR T-cell therapy safety regulations (30:23) CME information and select publications

Drug Diversion Insights with Terri Vidals
Securing the Unsecured: A Mayo Clinic Study on Propofol Disposal and Diversion Mitigation

Drug Diversion Insights with Terri Vidals

Play Episode Listen Later Dec 3, 2025 48:05


Propofol is one of the most vulnerable medications for diversion in healthcare — not because it lacks abuse potential, but because it lacks the regulatory oversight applied to controlled substances.In this episode of Rxpert Solutions, I'm joined by Michael T. Ring and Dale M. Pfrimmer to discuss their Mayo Clinic quality-improvement study published in Critical Care Nurse:“Propofol as a Drug of Diversion: Changing Disposal Practices to Reduce Risk.”Their work uncovered a major safety gap: before intervention, 44.1% of propofol bottles found in ICU waste bins were still full and accessible for diversion. After implementing activated carbon disposal pouches and specialized bottle-opening tools, that number dropped to zero.We explore:- The methodology behind their intervention- Overcoming education and workflow challenges- How environmental stewardship intersects with diversion prevention- Why their success led to system-wide adoption across all ICUs and the EDThis episode highlights how simple, practical changes can meaningfully reduce diversion risk and protect healthcare professionals — even for medications outside DEA scheduling.More from Rxpert Solutions: https://www.rxpert.solutions/?utm_source=spotify&utm_medium=insights&utm_campaign=mike-ring

The Fractional CFO Show with Adam Cooper
Insurance Without the BS - What Founders Actually Need to Know

The Fractional CFO Show with Adam Cooper

Play Episode Listen Later Dec 3, 2025 36:30 Transcription Available


This week I'm joined by Michael Henderson, Founder of RiskBox Ltd, a man on a mission to help creative businesses understand what insurance they really need.Michael brings a refreshingly honest take on one of the more confusing of running a businesses. He shares real stories, practical guidance, and insights that could save your business time, money and headaches when things go wrong.

Cloud Security Podcast by Google
EP254 Escaping 1990s Vulnerability Management: From Unauthenticated Scans to AI-Driven Mitigation

Cloud Security Podcast by Google

Play Episode Listen Later Dec 1, 2025 31:14


Guest: Caleb Hoch, Consulting Manager on Security Transformation Team, Mandiant, Google Cloud Topics: How has vulnerability management (VM) evolved beyond basic scanning and reporting, and what are the biggest gaps between modern practices and what organizations are actually doing? Why are so many organizations stuck with 1990s VM practices? Why mitigation planning is still hard for so many? Why do many organizations, including large ones, still rely on unauthenticated scans despite the known importance of authenticated scanning for accurate results? What constitutes a "gold standard" vulnerability prioritization process in 2025 that moves beyond CVSS scores to incorporate threat intelligence, asset criticality, and other contextual factors? What are the primary human and organizational challenges in vulnerability management, and how can issues like unclear governance, lack of accountability, and fear of system crashes be overcome? How is AI impacting vulnerability management, and does the shift to cloud environments fundamentally change VM practices? Resources: EP109 How Google Does Vulnerability Management: The Not So Secret Secrets! EP246 From Scanners to AI: 25 Years of Vulnerability Management with Qualys CEO Sumedh Thakar EP248 Cloud IR Tabletop Wins: How to Stop Playing Security Theater and Start Practicing How Low Can You Go? An Analysis of 2023 Time-to-Exploit Trends Mandiant M Trends 2025 EP204 Beyond PCAST: Phil Venables on the Future of Resilience and Leading Indicators Mandiant Vulnerability Management

Afternoon Drive with John Maytham
Were there any wins for Africa at COP30

Afternoon Drive with John Maytham

Play Episode Listen Later Dec 1, 2025 10:12 Transcription Available


Olivia Rumble, director of Climate Legal, speaks to Amy MacIver about the outcomes of the COP30 which were overshadowed here in South Africa by the G20 summit. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

Tennessee Home & Farm Radio
Deer Mitigation on Farms

Tennessee Home & Farm Radio

Play Episode Listen Later Nov 24, 2025 2:03


Farmers across Tennessee are growing increasingly frustrated as rising deer populations continue to devastate their crops. In an effort to protect their livelihoods, the agricultural industry is joining forces with the TWRA to pursue meaningful, long-term solutions to the deer overpopulation crisis on farmland.

The Scholars' Circle Interviews
Scholars’ Circle – Book Author interview – North : Future of Post climate America – November 23, 2025

The Scholars' Circle Interviews

Play Episode Listen Later Nov 24, 2025 58:01


Climate change will lead to climate migration. There has been a renewed interest in adaptation strategies. Mitigation efforts seek to limit the amount of greenhouse gases in the environment to slow climate change. But adaptation recognizes that the climate has changed and we as a society and as a planet must adapt to these rising … Continue reading Scholars' Circle – Book Author interview – North : Future of Post climate America – November 23, 2025 →

Circular Economy Podcast
171 Dr. Patrick Schröder: circular economy policymaking – progress and barriers

Circular Economy Podcast

Play Episode Listen Later Nov 23, 2025 46:14


Dr. Patrick Schröder, a senior research fellow at Chatham House, assesses the progress and barriers for circular economy policymaking. Patrick Schröder specializes in the circular economy, climate change, resource governance, and the Sustainable Development Goals (SDGs). His work brings together science, policy, and media to help further evidence-based policies, communicate complex sustainability issues, and promote equitable governance solutions at the multilateral level. Patrick is currently the Coordinating Lead Author for one of the three working groups for the IPCC Assessment Report 7, reporting on Mitigation of Climate Change, and he is also the Coordinating Lead Author for the UN Global Environment Outlook 7. Patrick holds a PhD in Environmental Studies, and is now studying part-time for a second PhD in circular and regenerative design with the Centre for Sustainable Design. In 2024, UNIDO and Chatham House published a ground-breaking global stocktake of 75 national circular economy roadmaps featuring more than 2,800 policy actions. The first roadmap, from Japan, was published in 1999, and since 2016, as governments strive to accelerate their circular transitions, over 70 countries have published national circular economy roadmaps and strategies. The review aims to ‘bridge knowledge gaps and shed light on critical aspects of these publications', and the authors point to a ‘significant lack of focus on the need to ensure a just and inclusive' transition, warning that a ‘lack of recognition of the need to work collaboratively with the global community' risks derailing a global just transition. Patrick tells us how he currently sees the global state of play for circular economy policies and roadmaps, where progress is happening and from a policymaking perspective, what is holding it back. The team at Chatham House have created a micro-site – circulareconomy.earth – and Patrick tells us more about that, and how we can use it. Stay in touch for free insights and updates…  Read on for more on our guest and links to the people, organisations and other resources we mention. Links we mention in the episode: Links for our guest: DISCOUNT CODE for A Circular Economy Handbook: How to Build a More Resilient, Competitive and Sustainable Business https://www.koganpage.com/CircEcon3 buy direct from the publisher Kogan Page, which ships worldwide (free shipping to UK and US) and you can use discount code KOGANPAGE25 for 25% off the book. This offer also applies to Kogan Page’s bundle option (print plus e-book for the same price as the print edition).  Read more about the book and download the Introduction: circulareconomyhandbook.com Read more about Patrick Schröder: https://www.chathamhouse.org/about-us/our-people/patrick-schroder Patrick Schröder's publications on Google scholar: https://scholar.google.com/citations?user=xeaCha8AAAAJ&hl=en Patrick Schröder on Linkedin: https://www.linkedin.com/in/patrick-schr%C3%B6der-b5789119/?originalSubdomain=uk The circular economy global policy microsite: circulareconomy.earth Books, people and organisations we mentioned The Chatham House paper launched during the Summit of the Future in NY:https://www.chathamhouse.org/2024/09/how-circular-economy-can-revive-sustainable-development-goals Patrick's paper on the SDGs and Circular Economy in the Journal of Industrial Ecology: https://www.researchgate.net/profile/Patrick-Schroeder-9/publication/344220320_The_Relevance_of_Circular_Economy_Practices_to_the_Sustainable_Development_Goals/links/5f85b316458515b7cf7c9143/The-Relevance-of-Circular-Economy-Practices-to-the-Sustainable-Development-Goals.pdf Human Development and Circular Economy paper (co-authored by Patrick Shroeder with Peter Desmond and Alex Lemile): https://www.sciencedirect.com/science/article/abs/pii/S0921344920300082 The Lancet Countdown on health and plastics https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01447-3/abstract Episode 166 Circularity Gap Report 2025: insights https://www.rethinkglobal.info/166-circularity-gap-report-2025-insights/   Episode 119 Ken Webster: the circular ECONOMY https://www.rethinkglobal.info/119-ken-webster-the-circular-economy/ Episode 119 Bonus Ken Webster: the circular ECONOMY! Part 2 https://www.rethinkglobal.info/119-bonus-ken-webster-the-circular-economy-part-2/ Guest bio Patrick Schröder is a senior research fellow at Chatham House. He specializes in the circular economy, climate change, resource governance, and the Sustainable Development Goals (SDGs).  He works at the intersection of science, policy, and media to advance evidence-based policies, communicate complex sustainability issues, and promote equitable governance solutions at the multilateral level. He currently serves as Coordinating Lead Author for the IPCC Assessment Report 7 (WG III – Mitigation) and Coordinating Lead Author for the UN Global Environment Outlook 7. He holds a PhD in Environmental Studies from Victoria University of Wellington, NZ, and currently studies part-time for a second PhD in circular and regenerative design with the Centre for Sustainable Design. Chatham House – The Royal Institute of International Affairs – is a world-leading policy institute based in London, dedicated to helping governments and societies build a sustainably secure, prosperous, and just world. The Environment and Society Centre (ESC) at Chatham House examines how environmental change intersects with global economics, politics, and society. Its work focuses on advancing systemic solutions to address climate change, resource governance, and accelerate circular economy transitions — fostering dialogue and evidence-based strategies that align environmental sustainability with social equity and geopolitical realities. Please let us know what you think of the podcast – and we'd love it if you could leave us a review on iTunes, or wherever you find your podcasts.  Or send us an email… Search for previous episodes….

Better Wealth with Caleb Guilliams
The Most Overlooked End-of-Year Tax Moves for High Earners (6 Advanced Tax Strategies)

Better Wealth with Caleb Guilliams

Play Episode Listen Later Nov 21, 2025 67:22


Learn the 6 most overlooked advanced tax strategies used by the wealthy before end of the year to make sure you keep as much money from the government as legally possible before 2026. Our guest is Roger Roundy, the CEO of Strategic Associates, a team of tax professionals committed to helping high income earners only pay what their legally supposed to and not a penny more.Want to Pay Less Taxes to the Government this Year? Connect with the Strategic Associates Team:Book a Call: https://bttr.ly/strategic-associatesEmail: support@strategicag.net Join the Waitlist for the Tax and Assets Community: https://taxandassets.comWant Us to Review Your Current Tax Strategy? Click Here: https://betterwealth.com/taxIntro - 0:00 End-of-Year Tax Planning for Business Owners - 1:39 Pay as Little Taxes to The Government as Possible - 4:30 Why You Need Advanced Tax Strategies - 6:58What Everyone Needs to Know About Taxes - 10:52Understanding 77,000 Pages of the Tax Code - 12:094 Categories of Advanced Tax Strategies - 13:09How Low Should You Keep Your Income? - 18:11 What is the Risk of Being Audited by the IRS? - 22:35How Many Clients of Yours Have Been Audited? - 26:41We Can't Talk About This on Youtube - 30:156 Advanced Tax Strategies Explained - 32:45 The Carry-Forward Losses Strategy - 34:41Tax Code 704B Deferral Strategy - 39:06The Difference Between Deferral & Mitigation - 40:10The "Donation" Volume Strategy - 44:00 Depreciation, Leverage, & Trusts Strategy - 48:39Solar Energy Tax Strategies - 52:53 Tax Code 831B | Captive Insurance - 57:00How to Connect - 1:02:46______________________________________________ Learn More About BetterWealth: https://betterwealth.com====================DISCLAIMER: https://bttr.ly/aapolicy*This video is for entertainment purposes only and is not financial or legal advice.Financial Advice Disclaimer: All content on this channel is for education, discussion, and illustrative purposes only and should not be construed as professional financial advice or recommendation. Should you need such advice, consult a licensed financial or tax advisor. No guarantee is given regarding the accuracy of the information on this channel. Neither host nor guests can be held responsible for any direct or incidental loss incurred by applying any of the information offered.

Kelley Drye Legal Download
Environmental Auditing and Penalty Mitigation: Leveraging EPA's Audit Policy Under the Trump Admin

Kelley Drye Legal Download

Play Episode Listen Later Nov 20, 2025 30:36


The Trump Administration's U.S. Environmental Protection Agency (EPA) is shifting its enforcement approach from aggressive actions to more cooperative mechanisms, such as compliance assistance programs and voluntary self-disclosure. For regulated industries such as manufacturing, heavy industry, and mineral extraction, this creates an opportunity to strengthen compliance while reducing enforcement risk. EPA's long-standing Audit Policy offers significant benefits, ranging from elimination or reduction of civil penalties to tailored incentives for new owners and clearer correction timelines. Successfully leveraging the policy, however, requires careful planning, strategic decisions on disclosure, and an understanding of potential risks. Co-hosted by Kelley Drye and Fehr Graham, this podcast version of the webinar features Kelley Drye Partners Wayne D'Angelo and Joseph Green and Fehr Graham's Matt Schroeder, EHS Practice Lead. Together, they share practical guidance on how companies can use EPA's Audit Policy to manage compliance obligations, mitigate penalties, and minimize enforcement exposure. Theyvexplore: - Recent policy shifts at EPA under the Trump Administration and their implications for regulated industries - The benefits of EPA's Audit Policy and the New Owner Audit Policy - Key considerations and potential risks when undertaking audits and disclosures - Practical tips to preserve privilege and maximize penalty mitigation - Insights into EPA's coordination with state agencies and how that impacts disclosure decisions To view the slide deck, click here: https://s3.amazonaws.com/cdn.kelleydrye.com/content/uploads/Environmental-Auditing-and-Penalty-Mitigation_Leveraging-EPAs-Audit-Policy-Under-the-Trump-Administration.pdf To view the full Zoom recording of the wfebinar, click here: https://vimeo.com/1129965500/6bac9e3b70?share=copy&fl=sv&fe=ci

Unfrozen
108. NORTH

Unfrozen

Play Episode Listen Later Nov 16, 2025 52:20


Jesse M. Keenan is the Favrot II Associate Professor of Sustainable Real Estate and Urban Planning at the School of Architecture and the Built Environment at Tulane University. In his upcoming book North: The Future of Post-Climate America, he outlines the complexities of America's handling of climate change and its effects on not only migration, mitigation, and real estate, but also our institutions and societal fabric. Simultaneous conclusions: There are no climate havens, but adapt we will. Join us for the fascinating Unfrozen interview. -- Intro/Outro: “System Error,” by The Cooper Vane --   Discussed: San Francisco Federal Reserve Bank report on reversal of the migration to the Sun Belt “What Climate Change Will Do to America by Mid-Century” - The Atlantic Climate gentrification: from theory to empiricism in Miami-Dade County, Florida Sean Becketti, Freddie Mac, April 2016: Will Markets Absorb Climate Change? A Climate Minsky Moment? Mitigation vs adaptation vs resilience Rachel Minnery's efforts at the AIA to include climate adaptation as part of architects' standards and duty of care “Climate-proof Duluth” in the New York Times There were never any climate havens: The Guardian The lesson of Asheville: The flooding was the beginning of its role as a “receiving zone,” not the end “Climate havens” = media clickbait Marketing of Buffalo as a “climate haven” by Mayor Byron R. Brown Alan Mallach's Unfrozen take on reviving legacy cities “This is about growth management and urban planning 101 at the regional and local level” For many “climate havens” rhetoric is not about recruiting new residents; climate mobility is a rhetorical arm for the existing residents for core sustainability development. “The Midwest will ultimately grow for the exact same reason the Sun Belt grew” Storming the Wall by Todd Miller The Climate Credit Score Hurricane Pass, Pinellas County, Florida “Sodom & Gorlando” Climate intelligence arms race, e.g., AlphaGeo Spencer Glendon – “The money is slow and dumb”

Ten Across Conversations
10X Convergence: The Region's Experts Convene to Address the Insurability Crisis

Ten Across Conversations

Play Episode Listen Later Nov 14, 2025 34:02


In October, stakeholders representing an unusual combination of sectors — public, private, academic, non-profit and journalism — gathered with insurance industry experts at the 10X Convergence in Jacksonville, Florida, to explore solutions to unsustainable insurance and disaster recovery costs throughout the Interstate 10 region.Insurers continue to cancel homeowners policies across California, Texas, Louisiana, and Florida as exposure to accelerating billion-dollar disasters undermines carriers' ability to pay out claims while remaining solvent. The industry crisis has begun to spread northward, where a widening Tornado Alley sees growing impacts from property-damaging storms.  This is a complex, all-hands-on-deck issue. Insurance practices and building standards have not adapted to the realities of climate change, and have neglected potential to be of powerful mutual support to one another. On the whole, 10X Convergence participants were clear that viable solutions will require a combination of applied climate and economic research with proactive governance and communications strategies, and that this must be matched by industry willingness to innovate its systems of underwriting and community development.  In this podcast, Ten Across journalists Maya Chari and Taylor Griffith take you through the problems and potential solutions discussed by the diverse group of experts at the 10X Convergence.  Relevant Articles and Resources  VIDEO: 10X Convergence Event Wrap Up  “It's harder to get home insurance. That's changing communities across the U.S.” (NPR, November 2025)  “They survived the hurricane. Their insurance company didn't.” (Grist, November 2025)  “Insurance for Physical Climate Risk Management: Lessons from History” (Carnegie Endowment for International Peace, August 2025)  “Next to Fall: The Climate-Driven Insurance Crisis is Here—And Getting Worse” (Senate Budget Committee, December 2024)  Relevant Ten Across Conversations Podcasts  The Future of Insurability: New Approaches and Mindsets Carolyn Kousky on Using Insurance Models to Drive Positive Change  Checking in with Dave Jones on California's Insurance Outlook  CreditsHosts: Maya Chari and Taylor GriffithProducer and editor: Taylor GriffithMusic by: Out To The World, Marten Moses, Lennon Hutton, and Pearce RoswellResearch and support provided by: Duke Reiter, Kate Carefoot, Rae Ulrich, and Sabine Butler  Guest Bios (in order of appearance):  Steve Bowen is the Chief Science Officer and meteorologist at Gallagher Re.  Adam Reeder is a civil-structural engineer and principal investigator at CDM Smith.  Juliet Rogers is the president of Blue Cottage at CannonDesign.  Laura Phillips-Edgecombe is the duPont Fund principal for public spaces and executive on loan to the City of Jacksonville, Florida.  Clint Noble is a member of the City of Jacksonville Environmental Protection Board and professional geologist with CDM Smith.  Dr. Quinton White is founding executive director of the Marine Science Research Institute and professor emeritus at Jacksonville University.  Alex Harris is the lead climate reporter for the Miami Herald.  Pete Nelson is the communications director for the Gulf Research Program at the National Academies of Sciences, Engineering, and Medicine.  Dave Hondula is the director of the Office of Heat Response and Mitigation at the City of Phoenix.  Casi Callaway is the founder and president of Activate Build Connect.  Eric Corey Freed is the director of sustainability at CannonDesign.  Sarina Beges is the associate director of philanthropy and social innovation at the Aspen Institute.  Ashantae Green is the sustainability manager for the City of Jacksonville, Florida.

Unlock Your Wealth Today
The 1031 Alternative for Real Estate Tax Mitigation

Unlock Your Wealth Today

Play Episode Listen Later Nov 14, 2025 3:08


Selling real estate comes with a few well-known options, but none of them are perfect. Take the 1031 exchange: you have just 45 days to identify a property and 180 days to close. The financing has to line up, and you're stuck with contingencies that can cut your buyer pool in half. No wonder 60% of 1031 exchanges end up paying some or all the taxes anyway. Your next option? Just pay the tax. Depending on your state, that could mean losing 30% or more of your sale proceeds—money that's gone forever. Another option often promoted is the DST. Sounds good on the surface, but when you peel back the layers, you'll find heavy commissions—sometimes 12 to 16%—and steep fees. Add in strict rules on how you can exit, and in the end, the net return to you is often only about 5%. That just doesn't work for most investors. And while there are plenty of other programs being pitched, most don't pass the IRS's three required tests for tax deferral. At Q companies, they've done the due diligence—almost all of them fail at least one, and many fail all three. In an audit, that means you lose.   But there is a simpler way.   And the IRS already recognizes and even provides a publication for—Publication 537. It's called an Installment Sale Trust (IST). The documents to set it up are straightforward, about 11 pages, and it's direct, easy, and more critical, it's compliant.   That's why we're hosting a Virtual Financial Summit. We'll walk you through all of these options—the 1031 exchange, paying the tax, DSTs, and others—so you can see the benefits and drawbacks for yourself. Most importantly, we'll show you how the IST can help you potentially reach a zero-tax bracket.   Comment ZERO TAX to learn how to better manage your real estate investments. I'm Heather Wagenhals showing you how to mitigate taxes, now go out and Unlock Your Wealth today.   Visit UnlockYourWealth.com for more great resources, tools, and strategies to overcome your personal and professional challenges to get out of debt, achieve financial freedom and live life on your terms today!

Law School
Property Law Lecture Five: Landlord-Tenant Law

Law School

Play Episode Listen Later Nov 14, 2025 50:47


Seven-Lecture Series on Property Law Series Roadmaphttps://drive.google.com/file/d/1ceyxXw7KilPSTUMFf_Y8r6ktEzM_gm1Q/view?usp=sharingThis conversation delves into the complexities of property law, specifically focusing on the landlord-tenant relationship and leasehold estates. It covers essential topics such as the types of leasehold estates, landlord duties, tenant rights, the Fair Housing Act, and landlord tort liability. The discussion emphasizes the importance of understanding these concepts for legal exams and real-world applications, highlighting the evolving nature of housing law and the need for fairness and security in tenant protections.Key Points SummaryI. Leasehold Estates & Property StatusFour Leasehold Types: Landlord/Tenant Law recognizes:Term of Years: Fixed period, ends automatically.Periodic Tenancy: Successive terms, renews until notice (e.g., 30-60 days).Tenancy at Will: Both parties desire, no specific term, modern law often requires notice.Tenancy at Sufferance (Holdover): Tenant remains wrongfully; landlord can evict or bind to new lease.Lease vs. License: A lease grants possessory interest; a license is revocable permission to use, not possess.Property Characterization: A lease is both a property conveyance and a contract. Tenant has present possession; landlord retains future possession.II. Landlord Duties & Tenant RemediesDuty to Deliver Possession: Landlords must deliver actual physical possession (modern English Rule, especially for residential leases).Implied Covenant of Quiet Enjoyment (ICQE): Protects tenant from landlord's substantial interference; breach leads to actual or constructive eviction.Implied Warranty of Habitability (IWH): (Residential only) Landlord must maintain habitable property, free of health/safety threats. Non-waivable.IWH Remedies: Tenant can refuse/abate rent or "repair and deduct" without vacating.III. Constructive & Self-Help EvictionConstructive Eviction (CE): Landlord's breach substantially interferes, forcing tenant to leave. Requires:Substantial Interference (landlord's fault).Notice and Cure (landlord fails to fix).Goodbye (tenant vacates reasonably quickly).Prohibition of Self-Help: Modern law almost universally bans landlord self-help eviction, requiring judicial proceedings for public peace.Exclusion of Non-Tenants: Self-help is often allowed against non-tenants (e.g., licensees), denying them due process.Advocacy for Uniform Protection: Argument exists to extend self-help prohibition to all residential occupants for housing security and dignity.IV. Transfer & Mitigation of DamagesDuty to Mitigate: Modern trend (contract law) requires landlords to make reasonable efforts to relet premises if a tenant breaches, reducing tenant's liability.Assignment vs. Sublease:Assignment: Transfers entire lease term. Assignee is directly liable to landlord; original tenant remains secondarily liable.Sublease: Transfers part of the term. Sublessee has no direct relationship with landlord; original tenant remains fully liable.Understanding the distinction between leasehold estates and licenses is crucial.There are four main types of leasehold estates: term of years, periodic tenancy, tenancy at will, and tenancy at sufferance.Landlords have specific duties, including delivering possession and ensuring habitability.Constructive eviction allows tenants to leave without penalty if their enjoyment of the property is substantially interfered with.The implied warranty of habitability ensures that residential properties meet basic living standards.Landlords must mitigate damages when a tenant abandons the property.The Fair Housing Act prohibits discrimination based on protected classes.Landlords can be liable for injuries on the property under certain conditions.Negligence per se can establish landlord liability if safety statutes are violated.The legal status of tenants versus licensees significantly impacts eviction protections.

The Land Bulletin
Wildfire Mitigation 101: Protecting Your Land with Outlaw Forestry

The Land Bulletin

Play Episode Listen Later Nov 13, 2025 41:25


It's never too early to prepare for wildfire season, but it can be too late. This week, Haley is joined by Bryce Gidney of Outlaw Forestry to talk about wildfire mitigation, forest health, and what it really means to care for your land. They discuss the numerous ways you can set up your land for success - everything from selective thinning to creating defensible space and improving wildlife habitat. Doing things right the first time not only protects your land, but also your legacy and peace of mind. Change the way you think about fire, first health and the future of your ranch and tune in today. Chapters[0:00] Welcome & Introduction[4:50] What Effective Wildfire Mitigation Really Looks Like[9:10] Walkthrough of Bryce's On-Site Process[13:20] Planning for the Long-Term: Land Legacy and Access[17:30] Hunting Access & Habitat Enhancement[21:15] Where to Start: First Steps for Landowners[25:45] Rising Fire Risks and Longer Seasons[29:15] Proactive vs. Reactive Land Management[37:45] How Mastication Restores Burned Landscapes[40:00] Final Thoughts: Start Now, Protect What MattersLinksOutlaw ForestryNeed professional help finding, buying or selling a legacy ranch, contact us: Mirr Ranch Group 901 Acoma Street Denver, CO 80204 Phone: (303) 623-4545 https://www.MirrRanchGroup.com/

Tips, Tactics and Tools Podcast
063 - How ZeroEyes Uses AI to Save Lives

Tips, Tactics and Tools Podcast

Play Episode Listen Later Nov 11, 2025 49:14


In this episode, we sit down with Dustin Brooks, Co-Founder and Chief Customer Officer of ZeroEyes, to explore what inspired a mission to prevent future violence through AI-powered gun detection. A former Navy SEAL, Dustin shares how ZeroEyes combines cutting-edge technology with human verification to provide real-time situational awareness to schools, businesses, and communities. He discusses the evolution of camera security, the importance of layered protection, and the ethical standards that guide ZeroEyes' work. Tune in for an insightful look at the intersection of innovation, preparedness, and how collaboration across the industry can save lives. 02:20 – Dustin shares his background as a Navy SEAL and how ZeroEyes began. The founding question: Can existing cameras detect visible guns and give security teams real-time awareness to minimize harm? 06:20 – How ZeroEyes combines software with a managed human service 07:20 – The critical human factor: real people verifying every alert 10:15 – Why ZeroEyes invests heavily in its operations center to continually improve accuracy 18:00 – Adam explains how this software could assist Special Operators overseas 23:15  – Customer expectations: What do organizations want from AI gun detection? 25:20 – Educating customers: managing expectations and understanding limitations 28:55 – Mitigation vs. prevention 31:05 – ZeroEyes success criteria: 1) Responding quickly to an event, and 2) Tracking the situation as it unfolds 36:00 – "Everyone's got a plan until they've been punched in the face." How ZeroEyes helps teams triage and act fast. 38:15 – ZeroEyes economies of scale model 40:33 – Three arrests last weekend highlight the success of the product 44:50 – The Gun Violence Database: an educational resource on the ZeroEyes website  45:45 – "A rising tide raises all ships." Dustin's call for collaboration within the safety and security industry.

Get Outside (with Wyoming Game and Fish)
Walleye Mitigation at Buffalo Bill Reservoir

Get Outside (with Wyoming Game and Fish)

Play Episode Listen Later Nov 7, 2025 27:08


     An illegal introduction of Walleye at Buffalo Bill Reservoir sometime in the early 2000's added a new wrinkle to Wyoming Game and Fish Department management of the reservoir.  But a handful of strategies—one involving anglers—has succeeded in suppressing that fish species spread.  Wyoming Game and Fish Fisheries Biologist Jason Burckhardt joins us on the program…

WIFI & WATER
Today's Climate Adaption & Mitigation Tech Featuring Chris Gloninger | E043

WIFI & WATER

Play Episode Listen Later Oct 28, 2025 60:40


In this episode, Chris Gloninger joins Jarrett to discuss the intersection of the climate crisis and technology, focusing on climate resilience efforts, and the importance of both mitigation and adaptation strategies.They explore innovative climate technologies, the challenges faced by urban areas like Boston, and the role of community projects in enhancing climate resilience. The discussion also touches on the implications of the current climate crisis for real estate and insurance, personal actions individuals can take, and the potential of AI in addressing climate issues. Ultimately, the conversation emphasizes the need for proactive measures and community engagement in the fight against the climate crisis.CHAPTERS00:00 - Episode Intro00:21 - Chris Joins The Pod01:23 - Chris' Professional Background02:20 - Hurricane Sandy04:40 - NYC's Climate Preparedness07:41 - Can We Science Our Way Out Of The Climate Crisis?12:31 - Boston's Seaport16:04 - Climate Tech34:15 - Climate Crisis Impacting Real Estate44:53 - Audience Questions51:34 - AI's Impact On Climate58:17 - Noise & Signal TodayChris' X - https://x.com/ChrisGloningerChris' Instagram - https://www.instagram.com/chris.gloninger/Chris' LinkedIn - https://www.linkedin.com/in/chris-gloninger-cbm-ccm-83625753/Future Signal is a podcast hosted and produced by Jarrett Carpenter that explores tomorrow's tech today.All of Future Signal's content is not financial advice but rather edu-tainment. All of our episodes are available here on YT as well as wherever you listen to podcasts.Follow us on Social Media :X - https://www.twitter.com/futuresignalxyzInstagram - https://www.instagram.com/futuresignalxyz/Facebook - https://www.facebook.com/futuresignalxyzLinkedIn - https://www.linkedin.com/company/future-signal-xyz/Twitch - https://www.twitch.tv/futuresignalxyzFor more info on the podcast, please check out https://www.futuresignal.xyz/Episode's music by @Txmmy_Beats - https://www.youtube.com/c/TxmmyBeatsTo learn more about Future Signal's Host - https://www.jarrettcarpenter.com/

Wealth Formula by Buck Joffrey
530: A Tax Attorney Talks Tax Mitigation with Buck

Wealth Formula by Buck Joffrey

Play Episode Listen Later Oct 26, 2025 39:07


This week's Wealth Formula Podcast features an interview with a tax attorney. While I'm not a tax professional myself, I want to drill down on something we touched on briefly that is incredibly relevant to many of you: the so-called short-term rental loophole. If I were a high-earning W-2 wage earner, this would be at the top of my list to implement—and I know many of you are already doing it. The short-term rental loophole is one of those quirks in the tax code that most people don't even know exists, but once you do, it can be a total game-changer. Here's why. Normally, when you buy a rental property, depreciation losses can't offset your W-2 income. They're considered passive, and they stay stuck in that bucket. But short-term rentals—Airbnb, VRBO, whatever—work differently. If the average stay is seven days or less and you materially participate, the IRS doesn't classify it as passive. It becomes an active business.  That means the paper losses you generate can offset your ordinary income, even from your day job. Normally, you'd need a real estate professional status to get that benefit. This is the one situation where you don't. So let's walk through how it works. When you buy a residential property, the IRS requires you to depreciate the structure—the walls, roof, foundation—over 27½ years. On a million-dollar property, that's about $36,000 a year. It's a slow drip. A cost segregation study changes that. Instead of treating the property as one block of concrete and wood, it carves out the parts that don't last 27 years. Furniture, carpet, appliances, cabinets, and even ceiling fans—those are considered 5-year property. In other words, you can depreciate them much faster. Now add bonus depreciation. Instead of spreading those 5-year assets out over five years, the current rules let you write off most of them all at once in year one. Here's the example. You buy a $1,000,000 short-term rental and finance it at 70 percent loan-to-value. That means you put in $300,000 cash and borrow $700,000. A cost seg often shows about 30 percent of the property—roughly $300,000—is 5-year personal property. Thanks to bonus depreciation, you deduct that entire $300,000 immediately. So you put in $300,000 cash, and you got a $300,000 paper loss in the same year. In practical terms, you just deducted your entire down payment against your taxable income. This is what real estate professionals do all the time and why they often end up with no tax liability at all. In this case, it works for you as a W2 wage earner. And for that reason, I think its one of the most powerful tools out there for high paid professionals that is grossly underutilized. Remember, the biggest expense for most people is the amount of tax they pay—especially W2 wage earners. This strategy lets you use money you would otherwise pay the IRS to build a cash-flowing asset for yourself.  Listen to this week's Wealth Formula Podcast to learn other ways to legally pay less tax!

I29 Moo U Dairy
Four State Dairy Podcast: Episode 2-Mycotoxin Mitigation

I29 Moo U Dairy

Play Episode Listen Later Oct 24, 2025 28:56


Today's episode is a special edition as it's the second episode of Four State Dairy Nutrition and Management Conference's new podcast. Join Jim Salfer and Fred Hall as they sit down with Dr. Joel Pankowski and discuss mycotoxin mitigation and how it impacts dairy cattle nutrition.The Four-State Dairy Nutrition and Management Conference presents the latest research on nutrition and management of dairy cattle. This conference is a collaborative effort of Iowa State University Extension and Outreach, University of Illinois Extension, University of Minnesota Extension and University of Wisconsin-Extension.To view Dr. Pankowski's webinar recording, visit https://fourstatedairy.org/webinars.

MedicalMissions.com Podcast
Malaria mitigation project in rural Uganda health center

MedicalMissions.com Podcast

Play Episode Listen Later Oct 22, 2025


Despite great progress in eliminating malaria in the country, cases of malaria remain high in certain areas of Uganda. Understanding the epidemiology of cases and control is a vital component to a successful malaria mitigation project. Using a cloud-based electronic medical record we have created a pilot project to document and track malaria cases in a central Uganda health center. This type of technology can be utilized in other rural health centers to track malaria and other diseases. Speaker(s): Deborah Rodriguez Session webpage: https://www.medicalmissions.com/events/gmhc-2024/sessions/malaria-mitigation-project-in-rural-uganda-health-center

Firearms Radio Network (All Shows)
CloverTac Podcast 165 – Recoil Mitigation

Firearms Radio Network (All Shows)

Play Episode Listen Later Oct 16, 2025


Spartan Defense Website Podcast Powered By SDS Arms Call In Segment Powered By Gideon Optics ********** Become A YouTube Channel Member Amazon Influencer Store Visit The CloverTac Website Grab You Some Camorado Apparel

Feds At The Edge by FedInsider
Ep. 221 Building on the Zero Trust Foundation

Feds At The Edge by FedInsider

Play Episode Listen Later Oct 16, 2025 59:50


  Implementing Zero Trust in a complex federal environment includes protecting data. To reach this goal, CISA has updated its recommendations for Continuous Diagnostics and Mitigation program called the Data Model Document (DMD). It provides the audience with a mechanism to focus on the most recent relevant changes without having to review the document in its entirety.   Today, we sat down with three experts to unpack some of the expanded concepts.   The first challenge is understanding the variety of systems. For example,  Daniel Ane from the TSA shared that they had to report data from eighty different systems. The only time efficient way to collect this varying data is with specific tools.   There is also a matter of control. Mark Hadley from the PNL shares that much critical infrastructure is  owned by the private sector, which can limit what kind of data can be collected.   Finally, Brian Meyer from Axonius makes a practical observation. Let us say you have a set of tools that accomplish the job of accurate data collection. If one gets updated, it can throw the entire compliance process out the window.   It seems obvious that adhering to the strictures of the Data Model Management recommendations will assist in a move to Zero Trust, but administering DMD needs guidance and a data strategy that is practical.    

CloverTac Podcasts
Recoil Mitigation

CloverTac Podcasts

Play Episode Listen Later Oct 16, 2025 61:21


Spartan Defense Website Podcast Powered By SDS Arms Call In Segment Powered By Gideon Optics ********** Become A YouTube Channel Member Amazon Influencer Store Visit The CloverTac Website Grab You Some Camorado Apparel

The Florida Insurance Roundup from Lisa Miller & Associates
Episode 60: Episode 60 – Our Growing Catastrophe Risk

The Florida Insurance Roundup from Lisa Miller & Associates

Play Episode Listen Later Oct 13, 2025 34:40


A new report from Verisk predicts a “new reality” in future natural catastrophes, with unprecedented global losses to exceed $152 billion annually.  It's being driven by “frequency perils” − frequent events, such as daily afternoon summer storms and hurricanes, that are driving high-impact losses.Former Florida Deputy Insurance Commissioner Lisa Miller sits down with a Verisk modeler and a Florida property insurance company meteorologist and risk analyst, to discuss how catastrophe modeling works, how insurance companies use it to set homeowners rates, and its importance in understanding and mitigating extreme weather risks now and in the future.Show Notes  (For full Show Notes, visit https://lisamillerassociates.com/episode-60-our-growing-catastrophe-risk/) The podcast discusses the increasing frequency and severity of storms and their impact on property insurance rates, particularly in Florida.  Dr. Julia Borman is Assistant Vice President of the Regulatory and Rating Client Services Team at Verisk.  It's part of the data analytic firm's Extreme Event Solutions division, which assists clients in working with regulators and rating agencies on a variety of projects, including data calls, utilizing catastrophe modeling in rating plans, and stress tests.  Natalie Ferrari is a Meteorologist and Catastrophic Risk Analyst for American Integrity Insurance Company, based in Tampa, Florida.  She provides data-driven insights into developing storms and their potential impacts by leveraging Verisk's modeling.  Together, with host Miller, they explored the evolving landscape of catastrophic risk modeling in rate filings and regulatory processes, the intensifying impact of extreme weather, and the need for resilience and preparedness in the face of natural disasters that modeling can guide.Catastrophe Models: The Backbone of Modern InsuranceVerisk's newest report, Modeling Insured Catastrophe Losses: A Global Perspective for 2025, projects expected future global losses to exceed $152 billion annually.  That's up from the $132 billion annual average loss over the past five years.  Host Miller quoted Verisk Extreme Event Solutions President Rob Newbold's remarks on the September 2025 report, that “the modeled losses reflect a fundamental shift in the risk landscape.  Natural catastrophe losses are no longer statistical anomalies.  They are the new normal.”  Borman said the report's $152 billion figure is a particularly significant one, given that the actual global losses in 2024 were around $137 billion.  “Over half of it was what we call frequency peril loss.  You used to hear around the industry, folks were calling things like severe thunderstorms and wildfire ‘secondary perils.'  We don't call them that at Verisk anymore.  They are frequency perils based on the fact that they happen often, typically within a year and those can really aggregate up into a large proportion of an insurance company's overall loss for the year,” Borman said.The catastrophe models look at a variety of different perils, including hurricanes, earthquakes, flooding, wildfires, and winter storms.  “We were writing the report not just to understand the total amount of loss, but also the insurance gap that might exist around the world and where that was most prevalent,” she added.   (For full Show Notes, visit https://lisamillerassociates.com/episode-60-our-growing-catastrophe-risk/) 

UK Wine Show
Mireia Torres on Carbon Mitigation

UK Wine Show

Play Episode Listen Later Oct 10, 2025


Familia Torres are at the forefront of sustainability, find out what they are doing different with Mireia Torres, a fifth generation family member.

Freedomain with Stefan Molyneux
6130 THE TRUTH ABOUT MARRIAGE AND DIVORCE!

Freedomain with Stefan Molyneux

Play Episode Listen Later Oct 8, 2025 119:46


In this Sunday Morning Donors Livestream from October 5, 2025, philosopher Stefan Molyneux explores marriage complexities and government influence, challenging the belief that half of marriages end in divorce. He shares statistics, offers partner vetting and premarital counseling advice, and engages with commenters and callers on parenting and economic issues. Stefan emphasizes the societal implications of marriage and the need for open communication.Sources: https://freedomain.com/sources-the-truth-about-marriage-and-divorce/SUBSCRIBE TO ME ON X! https://x.com/StefanMolyneuxFollow me on Youtube! https://www.youtube.com/@freedomain1GET MY NEW BOOK 'PEACEFUL PARENTING', THE INTERACTIVE PEACEFUL PARENTING AI, AND THE FULL AUDIOBOOK!https://peacefulparenting.com/Join the PREMIUM philosophy community on the web for free!Subscribers get 12 HOURS on the "Truth About the French Revolution," multiple interactive multi-lingual philosophy AIs trained on thousands of hours of my material - as well as AIs for Real-Time Relationships, Bitcoin, Peaceful Parenting, and Call-In Shows!You also receive private livestreams, HUNDREDS of exclusive premium shows, early release podcasts, the 22 Part History of Philosophers series and much more!See you soon!https://freedomain.locals.com/support/promo/UPB2025

Climate 21
The Economics of Climate Risk: Gary Yohe on Abating, Adapting, and Surviving

Climate 21

Play Episode Listen Later Oct 1, 2025 41:52 Transcription Available


Send me a messageIn this week's episode of the Climate Confident Podcast, I sit down with Dr. Gary Yohe, one of the world's leading climate economists, long-time IPCC author, and a member of the Nobel Peace Prize, winning IPCC team of 2007. Gary has spent over four decades shaping how we understand climate change, not just as an environmental issue, but as a fundamental risk management challenge.We explore his powerful framework: abate, adapt, or suffer. These are, he argues, the only three choices humanity has left, and crucially, some level of suffering is now unavoidable. Mitigation slows the pace of warming, adaptation reduces impacts, but neither can eliminate all risks. The insurance crisis unfolding in California and beyond shows what happens when climate risks become uninsurable, raising the threat of financial instability on a global scale.Gary also reminds us that climate decisions must be iterative. Policies cannot be fixed for 100 years; they must evolve as science, technology, and risk tolerance change. He illustrates this with striking examples, from New York's evacuation planning after Hurricane Sandy to San Francisco's flexible approach to sea-level rise.Yet, despite the scale of the challenge, Gary insists on hope, not blind optimism, but the conviction, as Václav Havel wrote, that action makes sense regardless of outcome. It's this perspective that has kept him, and many others, working relentlessly on solutions for over 40 years.If you want to understand why climate change is ultimately a risk management problem, why insurance, finance, and resilience are inseparable, and why hope is a strategy we can't do without, this episode is essential listening.Podcast supportersI'd like to sincerely thank this podcast's amazing subscribers: Ben Gross Jerry Sweeney Andreas Werner Stephen Carroll Roger Arnold And remember you too can Subscribe to the Podcast - it is really easy and hugely important as it will enable me to continue to create more excellent Climate Confident episodes like this one, as well as give you access to the entire back catalog of Climate Confident episodes.ContactIf you have any comments/suggestions or questions for the podcast - get in touch via direct message on Twitter/LinkedIn. If you liked this show, please don't forget to rate and/or review it. It makes a big difference to help new people discover the show. CreditsMusic credits - Intro by Joseph McDade, and Outro music for this podcast was composed, played, and produced by my daughter Luna Juniper

Disaster Tough Podcast
Part 2: Charlie Kirk, Schools, & Mitigation | Jim Balthazar | Security & Law Enforcement Expert

Disaster Tough Podcast

Play Episode Listen Later Sep 25, 2025 34:46


Looking for more DTP Content? Check us our here: www.thereadinesslab.com/dtp-linksIn Part 2 of this three-part series, host John Scardena continues his conversation with Jim Balthazar, drawing on Jim's background in law enforcement, ATF Special Response Teams, and faith-based security leadership to unpack lessons from high-profile incidents and what they mean for community safety today.Topics Covered in Part 2The Charlie Kirk incident — rooftop vulnerabilities, the difference between local security resources and federal protective standards, and how evolving threats require new approaches such as counter-sniper teams, drones for observation, and protective design changes.Historical parallels — from JFK to modern-day open-air events, how notoriety and visibility create unique risks.Schools and safety drills — why “run, hide, fight” isn't always effective, the role of barricading, and why empowerment strategies can make a difference for students and staff.The role of parents and families — parents as the first line of defense, age-appropriate conversations with children, and the importance of monitoring online influences.Mitigation and risk management — balancing statistical rarity with catastrophic impact, and how organizations can prepare without creating paranoia.Key TakeawaysHigh-profile figures and open-air venues face unique risks that demand proactive security planning.Statistically rare events can still have catastrophic consequences, making risk management essential.Training and age-appropriate preparation for schools and families are more effective than fear-based approaches.Parents play a critical role in monitoring, guiding, and shaping safe environments for kids.Security must adapt as threats evolve — from rooftops to classrooms to community gatherings.Part One: Leadership in the FieldPart Three: Church SecurityMajor Endorsements: ImpulseBleeding Control Kits by Professionals for Professionalshttps://www.impulsekits.com Doberman Emergency Management Subject matter experts in assessments, planning and training https://www.dobermanemg.com The Readiness Lab Trailblazing Disaster Readiness through podcasts, outreach, marketing, and interactive eventshttps://www.thereadinesslab.com For Sponsorship Requests contact@thereadinesslab.com 314-400-8848 Ext 2#DisasterToughPodcast #EmergencyManagement #CrisisLeadership #DisasterResponse #ActiveShooterAwareness #PublicSafety #Resilience #SchoolSafety #IncidentCommand #SecurityLeadership #RiskManagement #CharlieKirk #UVU #ChurchSecurity

Universe Today Podcast
[Interview] Fighting Moon and Mars Dust with An Electric Shield

Universe Today Podcast

Play Episode Listen Later Sep 22, 2025 34:28


Dust is a big problem for Moon and Mars. It sticks to everything, breaks things, covers solar panels. So, how do you solve this problem? One possible solution is an electric shield that uses charged surfaces to repel the dust.

Opportunity Zones Podcast
Advanced Tax Mitigation Strategies: Roth Conversions & ROBS Explained (Episode 359)

Opportunity Zones Podcast

Play Episode Listen Later Sep 17, 2025 39:11


Tax attorney John Hyre joins Jimmy Atkinson to discuss advanced tax mitigation strategies for high-net-worth investors. From Puerto Rico residency to self-directed IRAs, Trump Accounts, Roth conversions, and ROBS, John shares practical insights on how investors can minimize their tax burden while avoiding costly mistakes. In this episode, you'll hear why John believes Roth conversions — when done correctly — are one of the most powerful planning tools available, and why he urges extreme caution with Rollover Business Startups (ROBS). He also explains the opportunity presented by the newly created Trump Accounts, the benefits of living and working in Puerto Rico, and the common compliance traps that can trip up investors. Show notes & summary: https://opportunityzones.com/2025/09/john-hyre-359/